A miticidal composition and use thereof

Abstract

The application belongs to the technical field of pesticides, and relates to a kind of miticides composition and its application, the miticides composition contains active ingredient A and active ingredient B;Active ingredient A is a compound of formula (I), active ingredient B is any one of lambda-cyhalothrin and fenpropathrin, the miticides composition has strong quick-acting property, shows synergistic effect within a certain proportion range, reduces use cost, reduces dosage, prolongs effective period and delays development of drug resistance.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of pesticide miticides, and particularly relates to a miticide composition containing pyrethroid and application thereof. BACKGROUND

[0002] Pyrethroid pesticides gradually replace organochlorine and other toxic insecticides with high efficiency, wide range of action, strong stability and relatively low toxicity, and are widely used in agricultural, forestry and residential pest control. Pyrethroid insecticides grow fastest among the four major types of insecticides. Pyrethroid is widely used, but also has problems such as easy resistance, high fish toxicity and low systemicity.

[0003] Lambda-cyhalothrin is a sodium ion channel modulator that acts on the insect nervous system. It can keep the sodium ion channel unblocked and cause excessive excitement of insects. In some cases, it can also cause nerve conduction blockage. Sodium channels are involved in the conduction of action potentials along the nerve axon. Fenpropathrin belongs to pyrethroid insecticides, and its action site is the nervous system of insects. It is effective against juvenile mites, nymphs and adult mites, and can be used to control various pests and mites in various crops. It has strong contact and stomach toxicity.

[0004] Pesticides play an important role in agricultural production and are one of the important means to ensure a good harvest. The use of compound or rotation of miticides is an important measure for the management of agricultural mite resistance. The rotation of miticides with different mechanisms of action can effectively delay the development of resistance, but during the rotation process, the use of single agents cannot effectively kill individuals that have developed resistance. Mites have small individuals, fast development, strong reproductive capacity, short generation cycle, small activity range and high inbreeding rate, which makes them have more opportunities to be exposed to drugs, and the resistance problem is more prominent than other crop pests. Therefore, it is of great significance to carry out research on the compound of high-efficiency miticides for the control of mites and the management of resistance. SUMMARY

[0005] To solve the above problems in the prior art, the application provides a miticide composition, which shows a synergistic effect on phytophagous mites within a certain proportion range, has the advantages of reducing use cost, reducing drug dosage, prolonging effective period and delaying development of resistance.

[0006] To solve the above technical problems, the application provides the following technical scheme: a miticide composition, which comprises active ingredient A and active ingredient B, wherein the active ingredient A is a compound of formula (I):

[0007]

[0008] The active ingredient B is any one of the pyrethroids;

[0009] Further, the pyrethroids mentioned are s-cypermethrin, θ-cypermethrin, β-cypermethrin, abamectin, deltamethrin, DDT, cypermethrin, dichlorvos, allethrin, pyrethrin, lambda-cyhalothrin, flufenacet, flufenacet, pendiflubenzuron, imidacloprid, thiamethoxam, flufenacet, cypermethrin, delta ... The following are listed: methamidophos, cypermethrin, methoxybenzoxyfenozide, high-efficiency cyhalothrin, bifenthrin, cyhalothrin, permethrin, cypermethrin, fenvalerate, fenvalerate, fenvalerate, propargite, propargite, thiamethoxam, trifluralin, biobenzoxyfenozide, bioallethrin, high-efficiency cyhalothrin, cyclopentylpropargite, cypermethrin, tetrafluorobenzyl, tetrafluoromethrin, tetrabromopyrethrin, fenvalerate, deltamethrin, deltamethrin, cypermethrin, cypermethrin, cypermethrin, pyrethrin, pyrethroid, bromocypermethrin, or pyrethrin.

[0010] Furthermore, the active ingredient B is either lambda-cyhalothrin or cypermethrin;

[0011] Furthermore, the mass ratio of active ingredient A to active ingredient B is 1:40 to 30:1;

[0012] Furthermore, the mass ratio of the compound of formula (I) to lambda-cyhalothrin is 1:25 to 25:1;

[0013] Furthermore, the mass ratio of the compound of formula (I) to cypermethrin is 1:20 to 20:1;

[0014] Furthermore, the mass ratio of the compound of formula (I) to lambda-cyhalothrin is 1:13 to 13:1;

[0015] Furthermore, the mass ratio of the compound of formula (I) to cypermethrin is 1:16 to 25:2;

[0016] Furthermore, the mass ratio of the compound of formula (I) to lambda-cyhalothrin is 1:25, 1:13, 2:15, 1:1, 15:2, 3:1, or 25:1;

[0017] Furthermore, the mass ratio of the compound of formula (I) to cypermethrin is 1:20, 1:16, 1:6, 4:3, 6:1, 25:2, or 20:1;

[0018] Further, the sum of the content of the sex component A and the active component B in the acaricidal composition is 1-95wt% based on the total weight of the acaricidal composition being 100wt%;

[0019] Further, the sum of the content of the active component A and the active component B in the acaricidal composition is 1-80wt%;

[0020] Further, the sum of the content of the active component A and the active component B in the acaricidal composition is 2-60wt%;

[0021] Further, the acaricidal composition comprises, in addition to the active components, an agriculturally acceptable auxiliary component selected from one or more of wetting agents, dispersants, emulsifiers, thickening agents, disintegrants, antifreezing agents, antifoaming agents, solvents, preservatives, stabilizers, synergists or carriers;

[0022] The wetting agent is selected from one or more of alkyl benzene sulfonate, alkyl naphthalene sulfonate, lignin sulfonate, sodium dodecyl sulfate, dioctyl succinate sodium sulfonate, alpha olefin sulfonate, alkyl phenol polyoxyethylene ether, castor oil polyoxyethylene ether, alkyl phenol ethoxylate, fatty alcohol ethoxylate, fatty alcohol polyoxyethylene ether sodium sulfate, silkworm excrement, soap nut powder, soapberry powder, SOPA, detergent, emulsifier 2000 series and wetting penetrant F; and / or

[0023] The dispersant is selected from one or more of lignin sulfonate, alkyl naphthalene sulfonate formaldehyde condensate, naphthalene sulfonate, triphenyl styryl phenol ethoxylate phosphate, fatty alcohol ethoxylate, alkyl phenol polyoxyethylene ether, alkyl phenol polyoxyethylene ether formaldehyde condensate sulfate, fatty amine polyoxyethylene ether, glycerol fatty acid ester polyoxyethylene ether, polycarboxylate, polyacrylic acid, phosphate, EO-PO block copolymer and EO-PO graft copolymer; and / or

[0024] The emulsifier is selected from one or more of calcium dodecyl benzene sulfonate, alkyl phenol formaldehyde resin polyoxyethylene ether, phenylethyl phenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styryl phenol polyoxyethylene ether, castor oil polyoxyethylene ether and alkyl phenol ether phosphate; and / or

[0025] The thickening agent is selected from one or more of xanthan gum, organic bentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose and white carbon black; and / or

[0026] The disintegrant is selected from one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid and tartaric acid; and / or

[0027] The antifreezing agent is selected from one or more of alcohols, alcohol ethers, chlorinated hydrocarbons, and inorganic salts; and / or

[0028] The antifoaming agent is selected from one or more of C 10 -C 20 The saturated fatty acid compound, silicone oil, silicone compound, C8-C 10 alcohol; and / or

[0029] The solvent is selected from one or more of benzene, toluene, xylene, mesitylene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethyl formamide, cyclohexanone, alkylene carbonate, diesel oil, solvent oil, vegetable oil, vegetable oil derivative, and water; and / or

[0030] The preservative is selected from one or more of propionic acid, sodium propionate, sorbic acid, sodium sorbate, potassium sorbate, benzoic acid, sodium benzoate, sodium p-hydroxybenzoate, methyl p-hydroxybenzoate, carboxin, and 1,2-benzisothiazolin-3-one; and / or

[0031] The stabilizer is selected from one or more of disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-cresol, triethanolamine oleate, epoxidized vegetable oil, kaolin, bentonite, attapulgite, white carbon, talc, montmorillonite, and starch; and / or

[0032] The synergist is selected from one or more of phosphorus synergist, and ether synergist; and / or

[0033] The carrier is selected from one or more of ammonium salt, ground natural mineral, ground artificial mineral, silicate, resin, wax, solid fertilizer, water, organic solvent, mineral oil, vegetable oil, and vegetable oil derivative;

[0034] Further, the acaricidal composition can be prepared into an agriculturally permissible formulation form selected from a solid formulation and / or a liquid formulation;

[0035] The solid formulation includes a powder, a granule, a pellet, a tablet, a bar, a wettable powder, an oil dispersible powder, a milk powder, a water dispersible granule, a milk granule, a water dispersible tablet, a soluble powder, a soluble tablet, or a soluble granule;

[0036] The liquid formulation includes a soluble liquid, a soluble gel, an oil, a spreadable oil, an emulsion oil, an emulsion, a dispersible liquid, a paste, an aqueous emulsion, an oil emulsion, a microemulsion, a lipid, a suspension, a microcapsule suspension, an oil suspension, a dispersible oil suspension, a suspoemulsion, a microcapsule suspension-suspension, a microcapsule suspension-aqueous emulsion, or a microcapsule suspension-suspoemulsion;

[0037] Further, the powder is a free-flowing powdery formulation suitable for dusting or spreading containing the active ingredient;

[0038] Further, the granules are particulate preparations containing active ingredients which are free-flowing within a certain particle size range;

[0039] Further, the pellets are spherical preparations (generally greater than 6 mm in diameter) containing active ingredients;

[0040] Further, the tablets are tabular preparations (generally having two flat faces or a convex face with a face spacing less than the diameter) containing active ingredients of a certain shape and size;

[0041] Further, the strips are strip or rod preparations (generally several centimeters in length and a few millimeters in width / diameter, i.e., length greater than diameter / width) containing active ingredients;

[0042] Further, the wettable powders are powdery preparations in which active ingredients are dispersed as a suspension in water;

[0043] Further, the oil-dispersible powders are powdery preparations in which active ingredients are dispersed as a suspension in an organic solvent;

[0044] Further, the emulsifiable powders are powdery preparations in which active ingredients are dissolved in an organic solvent and coated with a soluble or insoluble inert ingredient, and which form oil-in-water emulsions when dispersed in water;

[0045] Further, the water-dispersible granules are granular preparations which disintegrate in water and disperse active ingredients as a suspension;

[0046] Further, the emulsion granules are granular preparations in which active ingredients are dissolved in an organic solvent and coated with a soluble or insoluble inert ingredient, and which form oil-in-water emulsions when dispersed in water;

[0047] Further, the water-dispersible tablets are tabular preparations which disintegrate in water and disperse active ingredients as a suspension;

[0048] Further, the soluble powders are powdery preparations in which active ingredients form true solutions in water, and which can contain water-insoluble inert ingredients;

[0049] Further, the soluble granules are granular preparations in which active ingredients form true solutions in water, and which can contain water-insoluble inert ingredients;

[0050] Further, the soluble tablets are tabular preparations in which active ingredients form true solutions in water, and which can contain water-insoluble inert ingredients;

[0051] Further, the soluble solutions are liquid preparations which, when diluted with water, become transparent or translucent liquids containing active ingredients, and which can contain water-insoluble inert ingredients;

[0052] Further, the soluble paste is a colloidal preparation containing active ingredients in true solution after dilution with water;

[0053] Further, the oil agent is a homogeneous liquid preparation containing active ingredients after dilution (or without dilution) with organic solvent;

[0054] Further, the spreading oil agent is an oil agent containing active ingredients which automatically spreads into oil film on water surface;

[0055] Further, the emulsifiable concentrate is a homogeneous liquid preparation containing active ingredients after dilution and dispersion into emulsion with water;

[0056] Further, the emulsion is an emulsion preparation containing active ingredients after dilution and dispersion into emulsion with water;

[0057] Further, the dispersible liquid agent is a homogeneous liquid preparation containing active ingredients after dilution and dispersion into suspension with water;

[0058] Further, the paste is a water-based paste preparation containing active ingredients which can form film, generally used directly;

[0059] Further, the water emulsion is a emulsion liquid preparation formed by active ingredients (or organic solution thereof) in water;

[0060] Further, the oil emulsion is a emulsion liquid preparation formed by active ingredients (or aqueous solution thereof) in oil;

[0061] Further, the microemulsion is a transparent or translucent microemulsion liquid preparation formed by active ingredients in water, used directly or after dilution with water;

[0062] Further, the lipid agent is an oil or fat-based viscous preparation containing active ingredients, generally used directly;

[0063] Further, the suspension agent is a stable suspension liquid preparation formed by active ingredients dispersed in water as solid particles, generally used after dilution with water;

[0064] Further, the microcapsule suspension agent is a stable suspension liquid preparation formed by microcapsules containing active ingredients dispersed in liquid;

[0065] Further, the oil suspension agent is a stable suspension liquid preparation formed by active ingredients dispersed in liquid as solid particles, generally used after dilution with organic solvent;

[0066] Further, the dispersible oil suspension agent is a stable suspension liquid preparation formed by active ingredients dispersed in non-water medium as solid particles, generally used after dilution with water;

[0067] Further, the emulsifiable concentrate is a non-homogeneous liquid preparation in which the active ingredient is stably dispersed in the form of solid particles and water-insoluble microdroplets in a continuous aqueous phase.

[0068] Further, the microcapsule suspension-suspension is a stable suspension liquid preparation in which the active ingredient is dispersed in water in the form of microcapsules and solid particles.

[0069] Further, the microcapsule suspension-emulsifiable concentrate is a non-homogeneous liquid preparation in which the active ingredient is stably dispersed in the form of microcapsules, solid particles and water-insoluble microdroplets in a continuous aqueous phase.

[0070] Further, the microcapsule suspension-emulsifiable concentrate is a non-homogeneous liquid preparation in which the active ingredient is stably dispersed in the form of microcapsules, solid particles and water-insoluble microdroplets in a continuous aqueous phase.

[0071] Further, the solid preparation is selected from wettable powder and water dispersible granule; the liquid preparation is selected from emulsifiable concentrate, emulsion, and suspension.

[0072] Further, the preparation method of the wettable powder is to uniformly mix the active ingredient and other adjuvants, and then to pulverize them by an air flow pulverizer to a fineness that satisfies the requirement that at least 98 wt% passes through a 45 μm test sieve.

[0073] Further, the preparation method of the water dispersible granule is to add the active ingredient into a carrier, and to mix the carrier with a surfactant and other functional adjuvants, and then to add 10-25% water, and to knead, granulate, dry and sieve to obtain the water dispersible granule product.

[0074] Further, the preparation method of the emulsifiable concentrate is to add the active ingredient into a carrier, and to mix the carrier with a surfactant and other functional adjuvants, and then to obtain the emulsifiable concentrate product by stirring and mixing in a mixing kettle.

[0075] Further, the preparation method of the emulsion is to dissolve the active ingredient into a solvent, to add an emulsifier to make the active ingredient dissolve into a uniform oil phase, to mix deionized water and an antifreezing agent to make a uniform aqueous phase, to add the aqueous phase into the oil phase, to stir and mix uniformly, to add an antifoaming agent, and to form a well-dispersed emulsion product by high-speed shearing.

[0076] Further, the preparation method of the suspension is to sequentially place the active ingredient, a surfactant and other functional adjuvants into a reaction kettle, to mix them with water, to perform high-speed shearing and wet sanding, and to finally obtain the suspension product by uniform mixing and filtration.

[0077] Use of a miticidal composition for controlling harmful mites.

[0078] Further, the mite is Tetranychus cinnabarinus, also known as red spider mite, belonging to Arachnida Tetranychidae, widely distributed on mulberry, cotton, kidney bean, Chinese rose and other 100 kinds of plants, sucking the nutrients in plant leaf cells through the mouth needle, making the damaged parts gradually lose green and die, seriously damaging the normal development of plants.

[0079] Further, the acaricidal composition and / or its preparation are applied to the mite in need of control or the medium where the mite grows in an effective dose.

[0080] The beneficial effects of the present application are:

[0081] (1) The acaricidal composition of the present application has obvious synergistic effect at a certain ratio, especially has good control effect on Tetranychus cinnabarinus;

[0082] (2) Safe and efficient, can delay the development of mite resistance, and reduce the use amount of pesticide;

[0083] (3) Long-acting, can effectively control the crops from being damaged by mites during the whole growth period, is safe to crops, non-target organisms, beneficial organisms and natural enemies, and has the effect of increasing yield and ensuring harvest. DETAILED DESCRIPTION

[0084] In order to make the technical solutions, purposes and advantages of the present application clearer and more apparent, the present application is described by the following specific examples, but the present application can be realized in various forms and should not be limited by the examples described herein.

[0085] Preparation example:

[0086] Preparation example 1:

[0087] 20% compound of formula (I)· lambda-cyhalothrin suspension concentrate (3:1)

[0088] Preparation formula: 15% compound of formula (I), 5% lambda-cyhalothrin, 1.5% fatty alcohol polyoxyethylene ether, 1.5% polycarboxylic acid sodium salt, 3% alkyl aryl polyoxyethylene polyoxypropylene ether, 1% magnesium aluminum silicate, 0.2% xanthan gum, 0.1% methyl isothiazolinone, 5% ethylene glycol, 0.4% silicone defoaming agent, and deionized water to make up the balance;

[0089] Preparation method: according to the formula proportion of the example, the effective ingredients, surfactants and other functional additives are sequentially placed in a reaction kettle, mixed uniformly with oil, sheared at high speed, wet sand ground, and finally filtered to obtain the suspension concentrate product.

[0090] Preparation example 2:

[0091] 30% compound of formula (I)· lambda-cyhalothrin suspension concentrate (2:1)

[0092] Preparation: 20% of the compound of formula (I), 10% of lambda-cyhalothrin SC, 1.5% of sodium dioctyl sulfosuccinate, 3.5% of sodium lignosulfonate, 2.5% of naphthalene sulfonate formaldehyde condensate, 0.5% of polyether, 1% of magnesium aluminum silicate, 0.2% of xanthan gum, 0.1% of methyl isothiazolinone, 5% of glycerol, 0.4% of silicone antifoaming agent, deionized water to make up the balance;

[0093] Preparation: same as Preparation Example 1.

[0094] Preparation Example 3:

[0095] 24% of the compound of formula (I) · cypermethrin SC (11:1)

[0096] Preparation: 20% of the compound of formula (I), 10% of lambda-cyhalothrin SC, 1.5% of sodium dioctyl sulfosuccinate, 3.5% of sodium lignosulfonate, 2.5% of naphthalene sulfonate formaldehyde condensate, 0.5% of polyether, 1% of magnesium aluminum silicate, 0.2% of xanthan gum, 0.1% of methyl isothiazolinone, 5% of glycerol, 0.4% of silicone antifoaming agent, deionized water to make up the balance;

[0097] Preparation: same as Preparation Example 1.

[0098] Preparation Example 4:

[0099] 28% of the compound of formula (I) · cypermethrin SC (15:13)

[0100] Preparation: 20% of the compound of formula (I), 10% of lambda-cyhalothrin SC, 1.5% of sodium dioctyl sulfosuccinate, 3.5% of sodium lignosulfonate, 2.5% of naphthalene sulfonate formaldehyde condensate, 0.5% of polyether, 1% of magnesium aluminum silicate, 0.2% of xanthan gum, 0.1% of methyl isothiazolinone, 5% of glycerol, 0.4% of silicone antifoaming agent, deionized water to make up the balance;

[0101] Preparation: same as Preparation Example 1.

[0102] Preparation Example 5:

[0103] 4.5% of the compound of formula (I) · lambda-cyhalothrin EC (5:4)

[0104] Preparation: 2.5% of the compound of formula (I), 2% of lambda-cyhalothrin, 12% of benzyl dimethyl phenol polyoxyethylene ether, 6.5% of sodium dodecyl sulfate, 15% of fatty alcohol polyoxyethylene ether, methyl oleate to make up the balance.

[0105] Preparation: the effective ingredients are put into the carrier according to the formulation proportion of the example, and the surfactants and other functional adjuvants are added therein, and then stirred and mixed uniformly in a stirring mixing kettle to obtain the EC product.

[0106] Preparation Example 6:

[0107] 7.5% Compound (I)·Cypermethrin EC (4:1)

[0108] Preparation formula: 6% compound of formula (I), 1.5% cypermethrin, 18% propylene carbonate, 5.5% sodium dodecylbenzenesulfonate, 10% fatty alcohol polyoxyethylene ether, 5.2% soybean oil, and methyl oleate to make up the balance;

[0109] Preparation method: Same as in preparation example 5.

[0110] Example 7:

[0111] 40% Formula (I) Compound·High-efficiency cyhalothrin water-dispersible granules (3:1)

[0112] Preparation formula: 30% of compound (I), 10% high-efficiency cyhalothrin, 6% sodium lignosulfonate, 10% naphthalenesulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 6% bentonite, and kaolin to make up the balance;

[0113] Preparation method: According to the formula ratio, the active ingredients are added to the carrier, and surfactants and other functional additives are added to it. After mixing, the mixture is pulverized by air jet and 10-25% water is added. Then, the mixture is kneaded, granulated, dried and sieved to obtain the water-dispersible granule product.

[0114] Example 8:

[0115] 42% Formula (I) Compound·Cypermethrin Water Dispersible Granules (4:3)

[0116] Preparation formula: 24% compound of formula (I), 18% cypermethrin, 6% sodium polycarboxylate, 10% naphthalenesulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 2% starch, 4% sodium sulfate, and kaolin to make up the balance;

[0117] Preparation method: Same as in preparation example 7.

[0118] Indoor toxicity

[0119] The examples refer to Part 7 of the Guidelines for Indoor Bioassay of Pesticides: Determination of the Combined Effect of Mixtures NY / T1154.7-2006; Part 13 of the Guidelines for Indoor Bioassay of Pesticides: Insecticides Part 13: Leaf Disc Spraying Method NY / T1154.13-2008.

[0120] Test insect source: Tetranychus carmine (bred at the R&D center), selected female adult mites kept indoors and in the same physiological state. Temperature: (25±1)℃. Relative humidity: 65%±5%, photoperiod: 16 / 8h (L / D);

[0121] Test material preparation: Select the uniform growth of Vicia faba leaves, with puncher to make leaf disc, in the culture dish placed a wet sponge block, on the filter paper, filter paper on the leaf disc, 2 leaf discs per dish, the indoor rearing of adult mites inoculated to the leaf disc, 16 heads per dish.

[0122] Formulation of the drug: Select acetone to dissolve the original drug, and then dilute with 0.1% Tween-80 aqueous solution. Prepare single agent mother liquor respectively, and design the ratio according to the purpose of mixing, the activity of the drug, and configure 5 series of mass concentration according to the method of equal ratio.

[0123] Test method: Place the culture dish at the bottom of the Potter spray tower for spraying, and the amount of spray liquid is 1ml. After 1min of liquid settlement, take it out and transfer it to the feeding condition for feeding.

[0124] Test repetition: Each treatment has not less than 4 times of repetition, and a treatment without drug (containing all organic solvents and emulsifiers) is set as blank control.

[0125] Data statistics and analysis: Check the death of test insects 48h after treatment, and record the total number of mites and dead mites (death standard; use a needle to move the mite appendages, and the immobile is dead, and the mobile is live mite) respectively.

[0126] According to the investigation data, calculate the corrected mortality of each treatment.

[0127] According to the following formula, the calculation results are kept to two decimal places:

[0128]

[0129] In the formula:

[0130] P - mortality, unit: percentage (%);

[0131] K - represents the number of dead mites, unit: head;

[0132] N - represents the total number of mites in the treatment, unit: head.

[0133]

[0134] In the formula:

[0135] P1 - corrected mortality, unit: percentage (%);

[0136] P t - treatment mortality, unit: percentage (%);

[0137] P0 - blank control mortality, unit: percentage (%).

[0138] If the control mortality is < 5%, no correction is needed; if the control mortality is between 5% and 20%, correction is needed; if the control mortality is > 20%, the test should be repeated.

[0139] The data were processed by the method of probit analysis. The LC 50 values of the regression line of toxicity and its 95% confidence limits, and B values were calculated by DPS statistical analysis system to evaluate the activity of the test agent on the biological test material.

[0140] The co-toxicity coefficient (CTC value) of the mixture was calculated according to the following formula:

[0141]

[0142] In the formula:

[0143] ATI - the measured toxicity index of the mixture;

[0144] S - the LC 50 of the standard acaricide, in milligrams per liter (mg / L);

[0145] M - the LC 50 of the mixture, in milligrams per liter (mg / L).

[0146] TTI = TI A * P A + TI B * P B

[0147] In the formula:

[0148] TTI - the theoretical toxicity index of the mixture;

[0149] TI A - the toxicity index of agent A;

[0150] P A - the percentage content of agent A in the mixture, in percentage (%);

[0151] TI B - the toxicity index of agent B;

[0152] P B - the percentage content of agent B in the mixture, in percentage (%).

[0153]

[0154] In the formula:

[0155] CTC - the co-toxicity coefficient;

[0156] ATI - the measured toxicity index of the mixture;

[0157] TTI - Theoretical Toxicity Index of the mixture.

[0158] The synergistic effect is shown when the CTC of the mixture is greater than 120, the antagonistic effect is shown when the CTC of the mixture is less than 80, and the additive effect is shown when the CTC of the mixture is between 80 and 120.

[0159] Test results:

[0160] The test results in Table 1 show that lambda-cyhalothrin has a high toxicity to T. cinnabarinus, with an LC 50 of 19.08 mg / L. The compound of formula (I) and lambda-cyhalothrin show a synergistic effect in the range of 1:25 to 25:1.

[0161] Table 1 Joint toxicity test of the compound of formula (I) and lambda-cyhalothrin in different ratios to T. cinnabarinus

[0162]

[0163] The test results in Table 2 show that fenpropathrin has a high toxicity to T. cinnabarinus, with an LC 50 of 18.244 mg / L. The compound of formula (I) and fenpropathrin show a synergistic effect in the range of 1:20 to 20:1.

[0164] Table 2 Joint toxicity test of the compound of formula (I) and fenpropathrin in different ratios to T. cinnabarinus

[0165]

[0166] Example 2 Field test for controlling T. cinnabarinus on peanuts

[0167] Test crop: peanuts, variety: Lu 8;

[0168] Test object: T. cinnabarinus;

[0169] Test site: Jining, Shandong Province, Jinxiang, peanut field, flat, previous crop was sweet potato, soil was sandy loam, and fertility was medium.

[0170] Test design: random arrangement, 4 repetitions for each treatment, plot area 20 m 2 .

[0171] Test time: May 2021, the test was carried out at the peak of T. cinnabarinus occurrence, and only one pesticide was applied during the whole test process.

[0172] Test agent:

[0173] 30% compound of formula (I) and lambda-cyhalothrin suspension concentrate (2:1);

[0174] 28% compound of formula (I) + fenpropathrin SC (15:13);

[0175] 4.5% compound of formula (I) + lambda-cyhalothrin EC (5:4);

[0176] 48% compound of formula (I) + fenpropathrin WG (4:3);

[0177] 5% lambda-cyhalothrin SC;

[0178] 16% fenpropathrin EW;

[0179] 20% compound of formula (I) SC.

[0180] Weather during the test: The weather was good on the day of the test and during the test.

[0181] Investigation method: The number of active mites was investigated before spraying and 1 day and 7 days after spraying, respectively. 10 peanuts in each treatment were randomly investigated, the whole plant was investigated, the number of active mites was recorded, and the mite population reduction rate was calculated.

[0182] Method for calculating efficacy: The efficacy was calculated according to the following formula:

[0183]

[0184]

[0185] During the test period, it was observed that the peanuts in each treatment grew well, and no phytotoxicity occurred in each treatment.

[0186] Test results:

[0187] Table 3: Field pesticide control test of Tetranychus cinnabarinus in peanut field

[0188]

[0189] Note: The control effect (%) in the above table is the average value of each repetition. Lowercase letters represent significant differences at the 5% level.

[0190] According to the field investigation, no adverse reactions of the leaves to the pesticides occurred in each treatment, indicating that each treatment is safe for peanut growth at the concentration used in the test.

[0191] Through indoor toxicity determination and tests on host in the field, the acaricidal composition of the present application shows good control effect on phytophagous spider mites. The acaricidal composition or its preparation obtained by compounding of the present application has significant control effect, and is superior to single agent in delaying the generation of resistance and prolonging the efficacy.

[0192] And no phytotoxicity of the complexing agent to crops is found in the test, which shows that the production cost and use cost can be reduced and the crops are safe in the case of the synergistic increase of the miticidal effect of the obtained miticidal composition or preparation.

[0193] Although the present application has been described in detail with general description and specific embodiments above, some modifications or improvements can be made on the basis of the present application, which is obvious to those skilled in the art, and thus, these modifications or improvements made on the basis of not deviating from the spirit of the present application, all belong to the scope of the present application.

Claims

1. A miticidal composition characterized in that: The acaricidal composition comprises active ingredient A and active ingredient B, wherein the active ingredient A is a compound of formula (I): (I), the active ingredient B is any one of lambda-cyhalothrin, cypermethrin, the mass ratio of the compound of formula (I) to lambda-cyhalothrin is 1:25-25:1; the mass ratio of the compound of formula (I) to cypermethrin is 1:20-20:

1.

2. The acaricidal composition according to claim 1, characterized by The mass ratio of the compound of formula (I) to lambda-cyhalothrin is 1:25, 1:13, 2:15, 1:1, 15:2, 3:1, 25:1; the mass ratio of the compound of formula (I) to fenpropathrin is 1:20, 1:16, 1:6, 4:3, 6:1, 25:2, 20:

1.

3. The acaricidal composition according to claim 1, characterized by The total weight of the acaricidal composition is 100wt%, the content of the active ingredient A and the active ingredient B in the acaricidal composition is 5-80wt%.

4. The acaricidal composition according to claim 1, characterized by The acaricidal composition comprises agricultural acceptable auxiliary ingredients in addition to the active ingredients, and the auxiliary ingredients are selected from one or more of wetting agents, dispersants, emulsifiers, thickening agents, disintegrating agents, antifreezing agents, antifoaming agents, solvents, preservatives, stabilizers, synergists or carriers.

5. The acaricidal composition according to claim 1, characterized by The acaricidal composition is prepared into a formulation selected from wettable powder, water dispersible granule, soluble granule, emulsifiable concentrate, water emulsion, microemulsion, suspension concentrate.

6. The acaricidal composition according to claim 5, characterized by 7. The use of the acaricidal composition according to any one of claims 1-6 for controlling the acarid, wherein the acarid is Tetranychus cinnabarinus. The acaricidal composition is applied to the acarid or the medium where the acarid grows in an effective amount.

8. Use according to claim 7, characterized in that, ​

Images