Antioxidant and anti-aging organic selenium health-care product and preparation method thereof

Abstract

The invention relates to the field of health-care products, and discloses an antioxidant and anti-aging organic selenium health-care product and a preparation method of the antioxidant and anti-aging organic selenium health-care product. Comprising the following raw materials in parts by weight: 0.1-0.3 part of organic selenium, 20-30 parts of a rehmannia root extract, 10-20 parts of a ginseng extract, 40-50 parts of a Chinese wolfberry fruit extract, 3-8 parts of vitamin E, 1-3 parts of zinc aspartate, 1-5 parts of alpha-ketoglutaric acid and 50 parts of maltodextrin. The strong free radical scavenging capacity is achieved through organic selenium, and various active ingredients in the radix rehmanniae extract, the ginseng extract and the fructus lycii extract have a synergistic effect from multiple aspects of regulating cell metabolism, enhancing cell viability and the like, so that the overall health state of an organism is improved; the vitamin E further strengthens an antioxidant defense line and blocks lipid peroxidation reaction; zinc aspartate assists the maintenance of normal physiological functions of the cells; and the alpha-ketoglutaric acid can delay the cell aging process.

Description

Technical Field

[0001] The invention relates to the technical field of health care products, in particular to an antioxidant and anti-aging organic selenium health care product and a preparation method thereof. Background Art

[0002] In the field of health care products, as people pay more attention to health, products with antioxidant and anti-aging functions are favored. As an essential substance for the human body, the trace element selenium is of great significance in maintaining the normal physiological functions of the body. Its antioxidant, anti-cancer, and heart protection effects have been widely studied and confirmed. At the same time, traditional Chinese herbal medicines are increasingly used in the field of health care due to their unique pharmacological activity. If the two can be effectively combined, it is expected that more effective health care products will be developed.

[0003] At present, there are a variety of widely used technical solutions in the research and development of antioxidant and anti-aging health products. As far as antioxidant ingredients are concerned, common vitamin substances such as vitamin C and vitamin E play an antioxidant role by neutralizing free radicals by providing hydrogen atoms. Selenium is a component of glutathione peroxidase, which can catalyze the conversion of reduced glutathione into oxidized glutathione, and at the same time reduce peroxides such as hydrogen peroxide, thereby reducing the generation of free radicals. In the market, both inorganic selenium and organic selenium are used. For anti-aging ingredients, plant extracts occupy an important position. In addition, some polysaccharides, such as shiitake polysaccharides, ganoderma polysaccharides, etc., are also used in anti-aging health products. They indirectly play a role in delaying aging by regulating the function of the immune system and enhancing the body's ability to repair damage.

[0004] However, in the actual application of traditional antioxidant and anti-aging organic selenium health products, the various antioxidant substances have different mechanisms of action and sites of action. Current products are often simply mixed without fully considering the synergistic relationship between them, resulting in the overall antioxidant effect not being optimal. Summary of the invention

[0005] In view of the deficiencies in the prior art, the present invention provides an antioxidant and anti-aging organic selenium health product and a preparation method thereof, so as to solve the problem that in the actual application of traditional antioxidant and anti-aging organic selenium health products, various antioxidant substances have different action mechanisms and action sites, and current products are often simply mixed without fully considering the synergistic enhancement relationship between them, resulting in the overall antioxidant effect failing to achieve the best.

[0006] To achieve the above objectives, the present invention is implemented through the following technical scheme: an antioxidant and anti-aging organic selenium health product, comprising the following raw materials in parts by weight: 0.1-0.3 parts of organic selenium, 20-30 parts of Rehmannia glutinosa extract, 10-20 parts of ginseng extract, 40-50 parts of wolfberry extract, 3-8 parts of vitamin E, 1-3 parts of zinc aspartate, 1-5 parts of α-ketoglutaric acid, and 50 parts of maltodextrin.

[0007] Preferably, the organic selenium is one of L-selenomethionine or L-selenomethylselenocysteine.

[0008] A method for preparing an antioxidant and anti-aging organic selenium health product comprises the following steps:

[0009] S1. Mixing the Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E in a mixer in parts by weight to obtain a mixture;

[0010] S2, adding organic selenium, vitamin E, zinc aspartate, α-ketoglutaric acid, and maltodextrin into water according to weight, stirring and dissolving, and filtering through a filter to obtain a uniform filtrate;

[0011] S3, after the mixture and the uniform filtrate are uniformly stirred by a stirrer, granulated by a granulator, and then dried, so as to obtain an antioxidant and anti-aging organic selenium health product.

[0012] Preferably, the particle sizes of the Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E in S1 are 80-150 meshes, and the weight proportion of water in S2 is 75 parts to 85 parts.

[0013] Preferably, the particle size of the antioxidant and anti-aging organic selenium health product in S3 is 0.5-1.5 mm.

[0014] Preferably, the moisture content of the antioxidant and anti-aging organic selenium health product in S3 is less than 2%.

[0015] Preferably, the antioxidant and anti-aging organic selenium health product in S3 is combined with magnesium stearate to prepare a dosage form of tablets.

[0016] Preferably, the antioxidant and anti-aging organic selenium health product in S3 is filled in capsules to prepare a dosage form of capsules.

[0017] The present invention provides an antioxidant and anti-aging organic selenium health product and a preparation method thereof.

[0018] Beneficial effects:

[0019] 1. The present invention uses organic selenium to exert a powerful free radical scavenging ability. Various active ingredients in Rehmannia root extract, ginseng extract and wolfberry extract work synergistically from multiple angles such as regulating cell metabolism and enhancing cell vitality to improve the overall health of the body; vitamin E further strengthens the antioxidant defense line and blocks lipid peroxidation reactions; zinc aspartate helps maintain the normal physiological functions of cells; α-ketoglutaric acid delays the aging process of cells, allowing them to promote each other and work synergistically in the body, greatly improving the overall antioxidant effect, thereby solving the problem of poor antioxidant effect.

[0020] 2. The present invention uses organic selenium as a key component of glutathione peroxidase, which can efficiently remove free radicals; vitamin E can block lipid peroxidation chain reactions; the active ingredients in Rehmannia glutinosa extract, ginseng extract and wolfberry extract also synergistically participate in the anti-oxidation process, so that the health product can more efficiently remove free radicals, protect cells from oxidative damage, and effectively delay the aging process caused by oxidative stress.

[0021] 3. The present invention regulates cell metabolism from multiple aspects by combining Rehmannia root extract, ginseng extract, wolfberry extract and α-ketoglutaric acid, which can promote cell repair and regeneration, enhance the function of mitochondria in cells, provide more energy for cells, and regulate related signal pathways, inhibit the expression of cell aging-related genes, make cells more capable of proliferation, and reduce the proportion of senescent cells, which helps to maintain the normal functions of various tissues and organs of the body and keep the body young.

[0022] 4. The present invention adopts L-selenomethionine or L-selenomethylselenocysteine ​​as an organic selenium source, which has extremely high bioavailability. It is stably present and efficiently absorbed in the human gastrointestinal tract, and synergistically acts with other ingredients to rapidly and stably increase the selenium content in the body. Adequate selenium content can enhance the activity of selenium-containing enzymes, further enhance the body's antioxidant, immune regulation and other functions, and maintain physical health in all aspects. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 The present invention provides a method flow chart for preparing an antioxidant and anti-aging organic selenium health product. DETAILED DESCRIPTION

[0024] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0025] The embodiment of the present invention provides an antioxidant and anti-aging organic selenium health product, comprising the following raw materials in parts by weight: 0.1-0.3 parts of organic selenium, 20-30 parts of Rehmannia glutinosa extract, 10-20 parts of ginseng extract, 40-50 parts of wolfberry extract, 3-8 parts of vitamin E, 1-3 parts of zinc aspartate, 1-5 parts of α-ketoglutaric acid, and 50 parts of maltodextrin.

[0026] Specifically, by adding organic selenium, it can be used as an important component of glutathione peroxidase to effectively remove free radicals in the body, reduce the oxidative damage of free radicals to cells, protect the structure and function of cells, and enhance the body's antioxidant capacity. At the same time, compared with inorganic selenium, organic selenium has higher bioavailability and lower toxicity, and is more conducive to human absorption and utilization.

[0027] By adding Rehmannia root extract, its effects in protecting the liver, delaying aging and anti-oxidation can be exerted, regulating related signal pathways, reversing cell aging caused by oxidative stress, promoting cell repair and regeneration, and improving the overall health of the body.

[0028] By adding ginseng extract, the various active ingredients it contains, such as ginsenosides, polysaccharides, amino acids, etc., can be used to improve the body's immunity and enhance the body's ability to resist disease; at the same time, it can play its anti-fatigue and anti-aging effects, improve the body's metabolism, increase the body's energy level, promote the regeneration of skin cells, and delay skin aging.

[0029] By adding wolfberry extract, the various biological activities of its main ingredient, wolfberry polysaccharides, can enhance immunity and immunoregulatory functions, promote hematopoietic function, lower blood lipids and resist fatty liver, while exerting its anti-tumor and anti-aging effects to maintain the body's physiological balance.

[0030] By adding vitamin E, it is possible to scavenge free radicals in the body, inhibit lipid peroxidation, and protect cells from oxidative damage, thereby delaying cell aging, maintaining normal cell function, and enhancing the body's antioxidant capacity.

[0031] By adding zinc aspartate, on the one hand, zinc can be supplemented for the human body. Zinc is a component and activator of many enzymes, participates in many physiological and biochemical processes of the human body, and is essential for maintaining normal metabolism and immune function of the body; on the other hand, aspartic acid, as a carrier, can supplement the amino acids needed by the human body, promote protein synthesis, and help maintain the normal physiological functions of the body, thereby playing an antioxidant and anti-aging role to a certain extent, and synergizing with other ingredients to enhance the overall efficacy of health products.

[0032] By adding α-ketoglutarate, mitochondrial bioenergy generation is promoted, cell vitality is improved, and the aging process is slowed down from the root; epigenetic regulation is affected, key signaling pathways that lead to aging are inhibited, and pathways that promote cell autophagy and repair are activated; inflammatory signaling pathways are regulated, the level of inflammatory factors in the body is reduced, and the risk of chronic diseases is reduced; the activity of hematopoietic stem cells and mesenchymal stem cells is enhanced, and self-repair of multiple tissues is promoted.

[0033] By adding maltodextrin, it acts as a filler and thickener to improve the physical properties of health products, allowing the raw materials to be evenly mixed to facilitate the preparation of suitable dosage forms. At the same time, it can also increase the stability and taste of the product, thereby improving the quality and acceptability of the product.

[0034] Through the coordination of various raw materials, the various ingredients can cooperate and promote each other, exerting more powerful antioxidant and anti-aging effects than single ingredients or simple mixtures; organic selenium and antioxidant ingredients such as vitamin E work together to form a more complete free radical scavenging system, effectively resisting the invasion of free radicals on cells. Zinc aspartate is a high-quality source of trace element zinc. After being absorbed by the human body, it can not only supplement the zinc that the human body lacks, but the carrier L-aspartic acid can also be used by the human body to supplement the amino acids needed by the human body. Zinc participates in the synthesis and activation of various enzymes in the body, which is essential to maintaining normal metabolism and physiological functions of cells. It cooperates with organic selenium, vitamin E and other ingredients to further strengthen the cell's antioxidant defense system and enhance the cell's ability to cope with oxidative stress.

[0035] Traditional Chinese herbal extracts such as Rehmannia extract, ginseng extract, and wolfberry extract synergize with α-ketoglutaric acid in regulating cell metabolism and delaying cell aging, affecting the cell aging process from different pathways, such as regulating signal pathways, promoting cell repair and regeneration, and enhancing cell vitality, thereby delaying the aging of the body in all aspects.

[0036] Maltodextrin ensures the stability and processability of the product, and provides a good foundation for the effective integration and presentation of other functional ingredients. Ultimately, through the synergistic cooperation of various raw materials, comprehensive and efficient antioxidant and anti-aging effects are achieved, thus solving the problem that in the actual application of traditional antioxidant and anti-aging organic selenium health products, various antioxidant substances have different action mechanisms and action sites. Current products are often simply mixed, and the synergistic enhancement relationship between them is not fully considered, resulting in the overall antioxidant effect not reaching the optimal problem.

[0037] Organic selenium is one of L-selenomethionine or L-selenomethylselenocysteine.

[0038] Specifically, L-selenomethionine and L-selenomethylselenocysteine, as typical representatives of organic selenium, have significant advantages over inorganic selenium. In terms of bioavailability, their chemical structure is similar to the body's own amino acid structure, and they are more easily absorbed and utilized by the body. After entering the human body, they can smoothly participate in the body's metabolism and be efficiently transported to tissues and cells that need selenium, so that selenium can more fully exert its physiological functions in the body. In terms of safety, these two types of organic selenium have low toxicity. Inorganic selenium may have obvious toxic side effects on the human body when taken in high doses. However, L-selenomethionine and L-selenomethylselenocysteine ​​are within the normal dosage range and have extremely low irritation and toxicity to the human body, greatly reducing the health risks caused by selenium supplementation.

[0039] From the perspective of antioxidant mechanism, as components of glutathione peroxidase and other selenium-containing enzymes, these selenium-containing enzymes play a key role in removing free radicals from the body and inhibiting lipid peroxidation. They can work synergistically with other antioxidant ingredients such as vitamin E to jointly build a more complete antioxidant defense system, more effectively reduce the damage of free radicals to cells, protect the cell's membrane structure, biological macromolecules such as proteins and DNA, and maintain the normal physiological function and activity of cells. In addition, L-selenomethionine and L-selenomethylselenocysteine ​​may also participate in regulating the human immune system, enhancing the body's immune function, and improving the body's resistance to disease, helping the body maintain a healthy state as a whole and better achieving antioxidant and anti-aging health benefits.

[0040] Please see attached Figure 1 , a method for preparing an antioxidant and anti-aging organic selenium health product, comprising the following steps:

[0041] S1. Stir and mix Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E in a mixer according to weight to obtain a mixture; the particle size of Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E in S1 is 80-150 mesh, and the weight of water in S2 is 75 parts to 85 parts.

[0042] Specifically, by mixing Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E by weight and controlling their particle size to 80-150 mesh, it is beneficial for the ingredients to be fully stirred and mixed evenly in the mixer. The appropriate particle size can increase the contact area between the ingredients, making the mixing process more efficient and uniform, ensuring that in the subsequent preparation process, each part can evenly contain various effective ingredients, laying the foundation for the consistency of the efficacy of the final product. Under this particle size, different raw materials can fully blend during mixing and exert their respective efficacy advantages. For example, the active ingredients of Rehmannia root extract can be better combined with other ingredients to jointly contribute to the antioxidant and anti-aging properties of the product.

[0043] S2, adding organic selenium, vitamin E, zinc aspartate, α-ketoglutaric acid, and maltodextrin into water according to weight, stirring and dissolving, and filtering through a filter to obtain a uniform filtrate;

[0044] Specifically, organic selenium, vitamin E, zinc aspartate, α-ketoglutaric acid and maltodextrin are added to water in parts by weight and stirred to dissolve; during this process, organic selenium (L-selenomethionine or L-selenomethylselenocysteine) can be evenly dispersed in the solution system due to its good solubility in water and fully contact with other ingredients; although vitamin E is a fat-soluble vitamin, it can also exist in the solution in a suitable dispersed state under specific formulations and stirring conditions, and cooperate with other water-soluble ingredients; after zinc aspartate is dissolved, it can provide zinc ions and L-aspartic acid to the system to participate in subsequent reactions and exert its efficacy; after α-ketoglutaric acid is dissolved, it is ready to work with other ingredients in the subsequent process of cell metabolism; the addition of maltodextrin not only helps the dissolution of other ingredients, but also adjusts the physical properties of the solution, making it easier for subsequent filtering operations; filtering by the filter can remove undissolved impurities or particles to obtain a uniform filtrate, thereby ensuring the purity and uniformity of the solution system and preparing for the next step of mixing with the mixture.

[0045] S3. After the mixture and the uniform filtrate are uniformly stirred by a stirrer, granulated by a granulator, and then dried to obtain an antioxidant and anti-aging organic selenium health product; the particle size of the antioxidant and anti-aging organic selenium health product in S3 is 0.5-1.5mm; the moisture content of the antioxidant and anti-aging organic selenium health product in S3 is less than 2%; the antioxidant and anti-aging organic selenium health product in S3 is combined with magnesium stearate to prepare a dosage form of tablets; the antioxidant and anti-aging organic selenium health product in S3 is filled in capsules to prepare a dosage form of capsules.

[0046] Specifically, the mixture obtained by S1 and the uniform filtrate obtained by S2 are stirred evenly by a stirrer, so that all the effective ingredients are fully mixed and blended. Subsequently, granulation is carried out by a granulator, and the uniformly mixed material is made into particles of a specific particle size, which is convenient for subsequent drying operations and is also beneficial to the dispersion and absorption of the product when taken. The drying process can remove moisture from the particles, so that the moisture content of the antioxidant and anti-aging organic selenium health product is less than 2%, reducing the impact of moisture on product stability and shelf life, and preventing the effective ingredients from being degraded or deteriorated due to the presence of moisture. The product can be further processed according to actual needs and combined with magnesium stearate to form tablets. Magnesium stearate, as a lubricant, can improve the formability and demolding properties of the tablets, making the tablets smooth in appearance and of appropriate hardness, which is convenient for patients to take. It can also be filled in capsules to form capsule dosage forms. The capsules can cover up the bad smell of the product, protect the effective ingredients from damage by environmental factors such as gastric acid, and ensure that the product is more effectively released and absorbed in the intestines, meeting the diverse needs of different consumers for product dosage forms, and ultimately obtaining organic selenium health products with antioxidant and anti-aging effects.

[0047] The following is further introduced in conjunction with specific embodiments:

[0048] Embodiment 1:

[0049] An antioxidant and anti-aging organic selenium health product comprises the following raw materials in parts by weight: 0.3 parts of organic selenium, 30 parts of rehmannia root extract, 20 parts of ginseng extract, 50 parts of wolfberry extract, 8 parts of vitamin E, 3 parts of zinc aspartate, 5 parts of alpha-ketoglutaric acid, and 50 parts of maltodextrin.

[0050] Organic selenium is one of L-selenomethionine or L-selenomethylselenocysteine.

[0051] A method for preparing an antioxidant and anti-aging organic selenium health product comprises the following steps:

[0052] S1. Mixing the Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E in a mixer in parts by weight to obtain a mixture;

[0053] S2, adding organic selenium, vitamin E, zinc aspartate, α-ketoglutaric acid, and maltodextrin into water according to weight, stirring and dissolving, and filtering through a filter to obtain a uniform filtrate;

[0054] S3, after the mixture and the uniform filtrate are uniformly stirred by a stirrer, granulated by a granulator, and then dried, so as to obtain an antioxidant and anti-aging organic selenium health product.

[0055] The particle sizes of the Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E in S1 are 115 meshes, and the weight portion of water in S2 is 80 parts.

[0056] The particle size of the antioxidant and anti-aging organic selenium health product in S3 is 1mm.

[0057] The moisture content of S3's antioxidant and anti-aging organic selenium health product is less than 2%.

[0058] The antioxidant and anti-aging organic selenium health product in S3 is combined with magnesium stearate to form a tablet.

[0059] The antioxidant and anti-aging organic selenium health product in S3 is filled in capsules to prepare a dosage form of capsules.

[0060] Embodiment 2:

[0061] The difference between this embodiment and the above-mentioned embodiment 1 is that:

[0062] An antioxidant and anti-aging organic selenium health product comprises the following raw materials in parts by weight: 0.1 parts of organic selenium, 20 parts of rehmannia root extract, 10 parts of ginseng extract, 40 parts of wolfberry extract, 3 parts of vitamin E, 1 part of zinc aspartate, 1 part of alpha-ketoglutaric acid, and 50 parts of maltodextrin.

[0063] Embodiment 3:

[0064] The difference between this embodiment and the above-mentioned embodiment 1 is that:

[0065] An antioxidant and anti-aging organic selenium health product comprises the following raw materials in parts by weight: 0.2 parts of organic selenium, 25 parts of rehmannia root extract, 15 parts of ginseng extract, 45 parts of wolfberry extract, 5.5 parts of vitamin E, 2 parts of zinc aspartate, 3 parts of alpha-ketoglutaric acid, and 50 parts of maltodextrin.

[0066] Table 1:

[0067]

[0068]

[0069] The above table compares traditional antioxidant and anti-aging organic selenium health products. Table 1 shows that different amounts of organic selenium, Rehmannia root extract, ginseng extract, wolfberry extract, zinc aspartate, α-ketoglutaric acid, and maltodextrin can affect the IC value of health products. 50 value, cell vitality, and selenium content in the body, thereby regulating antioxidant capacity, enhancing cell vitality, and increasing selenium content in the body, thereby optimizing and improving the antioxidant and anti-aging effects of health products, and solving the problem that traditional antioxidant and anti-aging organic selenium health products have failed to fully consider the synergistic relationship between them in actual applications, resulting in the overall antioxidant effect not being optimal.

[0070] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An antioxidant and anti-aging organic selenium health product, characterized in that: The invention comprises the following raw materials in parts by weight: 0.1-0.3 parts of organic selenium, 20-30 parts of rehmannia root extract, 10-20 parts of ginseng extract, 40-50 parts of wolfberry extract, 3-8 parts of vitamin E, 1-3 parts of zinc aspartate, 1-5 parts of alpha-ketoglutaric acid and 50 parts of maltodextrin.

2. An antioxidant and anti-aging organic selenium health product and a preparation method thereof according to claim 1, characterized in that: The organic selenium is one of L-selenomethionine or L-selenomethylselenocysteine.

3. A method for preparing an antioxidant and anti-aging organic selenium health product, characterized in that: The antioxidant and anti-aging organic selenium health product according to claim 1 or 2 comprises the following steps: S1. Mixing the Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E in a mixer in parts by weight to obtain a mixture; S2, adding organic selenium, vitamin E, zinc aspartate, α-ketoglutaric acid, and maltodextrin into water according to weight, stirring and dissolving, and filtering through a filter to obtain a uniform filtrate; S3, after the mixture and the uniform filtrate are uniformly stirred by a stirrer, granulated by a granulator, and then dried, so as to obtain an antioxidant and anti-aging organic selenium health product.

4. The method for preparing an antioxidant and anti-aging organic selenium health product according to claim 3, characterized in that: The particle sizes of the Rehmannia root extract, ginseng extract, wolfberry extract and vitamin E in S1 are 80-150 meshes, and the weight proportion of water in S2 is 75-85 parts.

5. The method for preparing an antioxidant and anti-aging organic selenium health product according to claim 1, characterized in that: The particle size of the antioxidant and anti-aging organic selenium health product in S3 is 0.5-1.5 mm.

6. The method for preparing an antioxidant and anti-aging organic selenium health product according to claim 1, characterized in that: The moisture content of the antioxidant and anti-aging organic selenium health product in S3 is less than 2%.

7. The method for preparing an antioxidant and anti-aging organic selenium health product according to claim 1, characterized in that: The antioxidant and anti-aging organic selenium health product in S3 is combined with magnesium stearate to form a tablet.

8. The method for preparing an antioxidant and anti-aging organic selenium health product according to claim 1, characterized in that: The antioxidant and anti-aging organic selenium health product in S3 is filled in capsules to prepare a dosage form of capsules.

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