Personal care composition

Abstract

Disclosed herein are personal care compositions. According to one aspect, there is provided a personal care composition comprising: (a) a surfactant system comprising at least one anionic surfactant and at least one amphoteric surfactant; and (b) at least one tear film protective agent, wherein the personal care composition has a pH ranging from about 4.0 to about 6.0.

Description

Technical Field

[0001] The present application relates to personal care compositions, and more specifically to personal care compositions comprising: (a) a surfactant system comprising at least one anionic surfactant and at least one amphoteric surfactant; and (b) at least one tear film protectant, wherein the personal care composition has a pH ranging from about 4.0 to about 6.0. Background Art

[0002] Personal care composition products such as body washes, shampoos, conditioners, and shower gels are becoming increasingly popular in the United States and around the world. A desirable personal care composition must meet many criteria. For example, in order to be accepted by consumers, a body wash composition should exhibit good cleaning properties, should exhibit good lathering properties, should be mild to the skin (not causing drying or irritation), and preferably should even provide conditioning benefits to the skin.

[0003] Shower gel (sometimes referred to as shower gel) is a generic term for describing a preparation containing a liquid surfactant for cleaning the body, while shampoo and conditioner are generic terms for describing a preparation containing a liquid surfactant for claiming and / or conditioning hair. Typically, personal care compositions can play a role in cleaning and / or conditioning the body (including both skin and hair). Although sometimes generally regarded as "soap", such personal care compositions do not typically include soap, such as sodium or potassium salts of fatty acids. Conventional personal care compositions typically include one of the multiple components including one or more surfactants, various emollients, fragrances and other personal care ingredients. When compared with common soap, conventional personal care compositions provide less skin irritation, improved foaming under hard water conditions, and leave less residue on skin and bathroom fixtures.

[0004] Typical personal care compositions are generally intended for use by adults. Young children (including infants and toddlers) may have more delicate, sensitive skin and may be more sensitive to eye irritation caused by accidental deposition of personal care compositions into the eyes due to body and / or hair washing processes. Therefore, many conventional personal care compositions may not be suitable for use by children due to irritating ingredients. Therefore, gentle, environmentally acceptable personal care compositions for young children are desired, such as products designated as "tear-free" body wash and / or shampoo formulations and / or products containing mostly natural ingredients or all-natural ingredients (including biodegradable ingredients). Summary of the invention

[0005] Summary of the invention is only intended to introduce a brief summary of some aspects of one or more embodiments of the present disclosure. According to the specific embodiments provided below, other applicable fields of the present disclosure will become apparent. Summary of the invention is not an exhaustive overview, nor is it intended to determine the key elements or important elements of this teaching, nor is it intended to delimit the scope of the present disclosure. On the contrary, its purpose is only to present one or more concepts in a simplified form as the preface of the following specific embodiments.

[0006] According to one aspect, a personal care composition is provided, comprising: (a) a surfactant system containing at least one anionic surfactant and at least one amphoteric surfactant; and (b) at least one tear film protectant, wherein the personal care composition has a pH in the range of about 4.0 to about 6.0, for example, a pH in the range of about 4.2 to about 6.8 or about 4.2 to about 5.2. In certain embodiments, the natural origin index of the personal care composition based on ISO standard 16128 can be about 90% or greater, for example, about 96% or greater or about 97% or greater.

[0007] According to certain aspects, the at least one anionic surfactant of the personal care composition disclosed herein is selected from sulfate anionic surfactants, such as sodium laureth sulfate (SLES). According to certain other aspects, the at least one anionic surfactant is selected from sulfolaurate surfactants, such as disodium 2-sulfolaurate, and in certain embodiments, the personal care composition is free or substantially free of sulfate anionic surfactants such as SLES. In certain embodiments, the at least one anionic surfactant is present in the personal care composition in an amount ranging from about 3 wt % to about 10 wt %, based on the total weight of the personal care composition.

[0008] According to certain aspects, the at least one amphoteric surfactant of the personal care composition disclosed herein is selected from betaine surfactants, such as cocamidopropyl betaine, optionally present in an amount ranging from about 5 wt % to about 20 wt % based on the total weight of the personal care composition.

[0009] According to certain aspects, the surfactant system of the personal care compositions disclosed herein further comprises at least one nonionic surfactant, such as a glucoside surfactant, preferably coco-glucoside.

[0010] According to certain aspects, the at least one tear film protectant of the personal care composition disclosed herein is selected from glycerin and glyceryl oleate, optionally present in an amount ranging from about 4 wt % to about 8 wt % based on the total weight of the personal care composition.

[0011] According to certain aspects, the surfactant system of the personal care composition disclosed herein further comprises a taurate surfactant, preferably sodium methyl oleyl taurate. In certain aspects, the personal care composition further comprises at least one preservative, such as a preservative selected from sodium benzoate and potassium sorbate, and in certain aspects, the personal care composition further comprises at least one anti-allergic agent, such as dipropylene glycol (DPG) or bisabolol. In certain aspects, the personal care composition disclosed herein does not contain a thickener, such as a thickener that is not another part of the surfactant system.

[0012] According to another aspect, a personal care composition is provided, comprising: (a) a surfactant system comprising disodium 2-sulfolaurate, a glucoside surfactant, and a betaine surfactant; and (b) at least two tear film protective agents, including glycerol and olein, wherein the personal care composition is free of sulfate anionic surfactants and has a pH ranging from about 4.0 to about 6.0. According to another aspect, a personal care composition is provided, comprising: (a) a surfactant system comprising a sulfate anionic surfactant and a betaine surfactant; and (b) at least two tear film protective agents, including glycerol and olein, wherein the personal care composition has a pH ranging from about 4.0 to about 6.0. DETAILED DESCRIPTION

[0013] For the purpose of illustration, the principle of the present disclosure is described by referring to a plurality of exemplary embodiments of the present disclosure. Although certain embodiments of the present disclosure are specifically described herein, it will be readily appreciated by those of ordinary skill in the art that the same principles are equally applicable to other compositions and methods and can be used in other compositions and methods. Before describing the disclosed embodiments of the present disclosure in detail, it should be understood that the present disclosure is not limited to the details of any particular embodiment disclosed herein in terms of its application. The terms used herein are for the purpose of description rather than limitation.

[0014] As used herein and in the appended claims, the singular forms "a", "an", and "the" include plural references unless the context dictates otherwise. The singular form of any class of components refers not only to one chemical substance within that class, but also to mixtures of these chemical substances. The terms "a" (or "a kind"), "one / kind or more / kind", and "at least one / kind" may be used interchangeably herein. The terms "comprising", "including", and "having" may be used interchangeably. The term "including" should be interpreted as "including, but not limited to". The term "comprising" should be interpreted as "including, but not limited to".

[0015] As used throughout, ranges are used as shorthand for describing the individual values ​​and each value within the range. Any value within the range can be selected as the end value of the range. Therefore, a range of 1 to 5 specifically includes 1, 2, 3, 4 and 5, and subranges such as 2 to 5, 3 to 5, 2 to 3, 2 to 4, 1 to 4, etc.

[0016] The term "about" when referring to a number means any number within 10% of the number. For example, the phrase "about 2 weight %" means a number between and including 1.8 weight % and 2.2 weight %.

[0017] All references cited herein are hereby incorporated by reference in their entirety. In the event of a conflict in a definition in the present disclosure and that of a cited reference, the present disclosure controls.

[0018] Unless otherwise indicated, abbreviations and symbols as used herein have their ordinary meanings. The abbreviation "wt%" means the percentage by weight relative to the personal care composition. The symbol "°" refers to degrees, such as temperature degrees or angle degrees. The symbols "h", "min", "mL", "nm" and "μm" refer to hours, minutes, milliliters, nanometers and micrometers, respectively. The abbreviation "rpm" means revolutions per minute.

[0019] When referring to chemical structures and names, the symbols "C", "H" and "O" mean carbon, hydrogen and oxygen, respectively. The symbols "-", "=" and "≡" mean a single bond, a double bond and a triple bond, respectively.

[0020] As used herein, "volatile" means a flash point below about 100°C. As used herein, "non-volatile" means a flash point above about 100°C.

[0021] Any member of a species list used to exemplify or define a genus may be mutually distinct from, overlap with, be a subset of, be equivalent to, be nearly identical to, or be identical to any other member of the species list. Furthermore, unless explicitly stated, such as when reciting Markush groups, a species list defining or exemplifying a genus is open-ended, given that there may be other species that define or exemplify the genus just as well as or better than any other species listed.

[0022] The phrase "a mixture thereof", "a combination thereof" or "a combination of two or more thereof" does not require that the mixture contains all of A, B, C, D, E and F (although it may contain all of A, B, C, D, E and F). Rather, it means a mixture that may include any two or more of A, B, C, D, E and F. In other words, it is equivalent to the phrase "one or more elements selected from A, B, C, D, E, F, and a mixture of any two or more of A, B, C, D, E and F". Likewise, the term "salt thereof" also relates to "salts thereof". Therefore, when the present disclosure refers to “an element selected from A, B, C, D, E, F, salts thereof, and mixtures thereof”, it means that it may include one or more of A, B, C, D and F, may include one or more of the salts of A, the salts of B, the salts of C, the salts of D, the salts of E and the salts of F, or may include a mixture of any two of A, B, C, D, E, F, the salts of A, the salts of B, the salts of C, the salts of D, the salts of E and the salts of F.

[0023] All components and elements affirmatively set forth in the present disclosure may be negatively excluded from the claims. In other words, the personal care compositions of the present disclosure may be free of or substantially free of all components and elements affirmatively recited throughout the present disclosure. In some cases, the personal care compositions of the present disclosure may be substantially free of unincidental amounts of ingredients or compounds described herein. An unincidental amount of an ingredient or compound is the amount of the ingredient or compound added alone to the personal care composition. For example, a personal care composition may be substantially free of unincidental amounts of an ingredient or compound, although such an ingredient or compound may be present as part of a raw material included in a blend of two or more compounds.

[0024] Some of the different categories of components identified may overlap. In such cases where there may be overlap and the personal care composition contains two components (or the composition contains more than two overlapping components), the overlapping compounds do not represent more than one component. For example, certain compounds may be referred to as both surfactants and emulsifiers. If a particular personal care composition contains both surfactants and emulsifiers, then a compound that may be referred to as both a surfactant and an emulsifier will only function as a surfactant or an emulsifier—not both.

[0025] For readability purposes, chemical functional groups are presented in their adjective form; for each adjective, the word "group" is assumed to be used. For example, the adjective "alkyl" without a noun following it should be read as "alkyl group."

[0026] Certain aspects of the present disclosure relate to personal care compositions, and preferably personal care compositions having a natural origin index of about 90% or greater, for example as measured in accordance with ISO Standard 16128. It has been found that personal care compositions formulated with certain surfactant systems can advantageously achieve the desired thickening while having a preferred natural origin index and / or biodegradability index, and are also mild enough for use on the delicate skin of young children or infants and do not cause undesirable eye irritation. ISO Standard 16128-1:2016 provides guidance for the definition of natural ingredients and organic cosmetic ingredients.

[0027] The personal care composition may have a Natural Origin Index of about 90% or greater, for example, as measured according to ISO Standard 16128. For example, in some embodiments, the personal care composition may have a Natural Origin Index according to ISO Standard 16128 of about 90% or greater, about 91% or greater, about 92% or greater, about 93% or greater, about 94% or greater, about 95% or greater, about 96% or greater, about 97% or greater, about 98% or greater, about 99% or greater, or about 99.5% or greater.

[0028] Additionally or alternatively, the personal care composition can achieve a biodegradability index of about 85% or greater, e.g., as measured according to ISO standard 14855-1: 2005. In some cases, the biodegradability index of the personal care composition, e.g., according to ISO standard 14855-1: 2005, can be about 85% or greater, about 87% or greater, about 88% or greater, about 89% or greater, about 90% or greater, about 91% or greater, about 92% or greater, about 93% or greater, about 94% or greater, about 95% or greater, about 96% or greater, about 97% or greater, about 98% or greater, about 99% or greater, or about 99.5% or greater.

[0029] According to one aspect, a personal care composition comprising a sulfate surfactant system or a sulfate-free surfactant system is provided. According to the personal care composition of certain embodiments, a surfactant system containing two or more surfactants may be included. The surfactant system generally includes two or more surfactants selected from a non-sulfate anionic surfactant, an amphoteric surfactant, a nonionic surfactant, and a combination of both or more thereof. For example, the surfactant system may include two, three, four, five, six, seven, eight, or nine or more surfactants. In some embodiments, the surfactant system includes two to eight, two to seven, two to six, two to five, two to four, three to seven, three to six, three to five, four to eight, four to seven, four to six, or any range or sub-range of surfactants. Preferably, the surfactant system may include two or more surfactants, wherein two or more surfactants are selected from different categories of anionic surfactants, amphoteric surfactants, and nonionic surfactants. For example, the surfactant system may include at least one non-sulfate anionic surfactant, at least one amphoteric surfactant, and at least one nonionic surfactant. In certain embodiments, the surfactant system may include at least one sulfate-based anionic surfactant and at least one amphoteric surfactant.

[0030] In certain embodiments, the personal care composition comprises a sulfate surfactant system containing at least one sulfate anion surfactant and / or its salt. The at least one sulfate anion surfactant and / or salt may, for example, include those selected from alkyl sulfate and alkyl ether sulfate. The alkyl sulfate and / or alkyl ether sulfate may have an alkyl group containing 8 to 20 carbon atoms, 8 to 16 carbon atoms, 10 to 16 carbon atoms, or 10 to 13 carbon atoms. Non-limiting examples of alkyl sulfate and alkyl ether sulfate include sodium lauryl sulfate (SLS), sodium dodecyl sulfate (SDS), sodium lauryl ether sulfate (SLES), ammonium lauryl sulfate, and ammonium laureth sulfate. In some embodiments, the sulfate anion surfactant includes sodium lauryl sulfate, sodium laureth sulfate, its salt, or a combination of both or more thereof. In certain embodiments disclosed herein, at least one sulfate anion surfactant is SLES.

[0031] In certain embodiments, the personal care composition comprises from about 1 wt. % to about 26 wt. % of a surfactant system comprising at least one sulfate anionic surfactant, wherein the percentages are based on the total weight of the personal care composition. For example, the surfactant system comprising at least one sulfate anionic surfactant can be present in the personal care composition in an amount ranging from about 1 wt % to about 23 wt %, from about 1 wt % to about 20 wt %, from about 1 wt % to about 18 wt %, from about 1 wt % to about 16 wt %, from about 1 wt % to about 14 wt %, from about 1 wt % to about 12 wt %, from about 1 wt % to about 10 wt %; from about 3 wt % to about 26 wt %, from about 3 wt % to about 23 wt %, from about 3 wt % to about 20 wt %, from about 3 wt % to about 18 wt %, from about 3 wt % to about 16 wt %, from about 3 wt % to about 14 wt %, from about 3 wt % to about 12 wt %, from about 3 wt % to about 10 wt % based on the total weight of the personal care composition. % to about 14 wt %, about 5 wt % to about 12 wt %, about 5 wt % to about 10 wt %; about 7 wt % to about 26 wt %, about 7 wt % to about 23 wt %, about 7 wt % to about 20 wt %, about 7 wt % to about 18 wt %, about 7 wt % to about 16 wt %, about 7 wt % to about 14 wt %, about 7 wt % to about 12 wt %, about 7 wt % to about 10 wt %; about 9 wt % to about 26 wt %, about 9 wt % to about 23 wt %, %, about 9 wt % to about 20 wt %, about 9 wt % to about 18 wt %, about 9 wt % to about 16 wt %, about 9 wt % to about 14 wt %, about 9 wt % to about 12 wt %; about 11 wt % to about 26 wt %, about 11 wt % to about 23 wt %, about 11 wt % to about 20 wt %, about 11 wt % to about 18 wt %, about 11 wt % to about 16 wt %, about 11 wt % to about 14 wt %, or any range or subrange thereof. In certain embodiments, the surfactant system comprising at least one sulfate anionic surfactant can be present in the personal care composition in an amount ranging from about 8 wt % to about 11 wt %, for example, from about 9 wt % to about 10 wt %, about 10 wt %, or about 9.8 wt %, based on the total weight of the personal care composition. In certain embodiments, the personal care composition comprises SLES as the sulfate anionic surfactant, and in certain embodiments, the SLES is present in the personal care composition in an amount ranging from about 8 wt % to about 11 wt %, e.g., from about 9 wt % to about 10 wt %, about 10 wt %, or about 9.8 wt %, based on the total weight of the personal care composition.

[0032] In some embodiments, the personal care composition comprises a surfactant system that is substantially free of or free of sulfate anionic surfactants. For example, the personal care composition can be formulated to have about 3 wt % or less, about 2 wt % or less, about 1 wt % or less, about 0.5 wt % or less, about 0.1 wt % or less, about 0.01 wt % or less, or about 0.001 wt % or less of sulfate anionic surfactants, such as undetectable amounts of sulfate anionic surfactants, based on the total weight of the personal care composition. In certain embodiments, the personal care composition is free of sulfate anionic surfactants, such as free of SLES.

[0033] In certain embodiments in which the personal care composition comprises a surfactant system that is substantially free of or free of sulfate-based anionic surfactants, the surfactant system may comprise at least one non-sulfate-based anionic surfactant. The non-sulfate-based anionic surfactant may be selected from sulfonate surfactants, taurate surfactants, isethionate surfactants, sarcosinate surfactants, sulfonate surfactants, sulfosuccinate surfactants, sulfoacetate surfactants, alkoxylated monoacid surfactants, salts thereof, and combinations of two or more thereof. In certain embodiments, the non-sulfate-based anionic surfactant is a long chain alkyl (e.g., C 6 To C 22 ) anionic surfactant. In certain embodiments, the non-sulfate-based anionic surfactant is disodium 2-sulfolaurate. The non-sulfate-based anionic surfactant can have an alkyl and / or acyl group containing 6 to 26 carbon atoms, 8 to 26 carbon atoms, 8 to 21 carbons, 8 to 16 carbon atoms, 10 to 16 carbon atoms, or 10 to 13 carbon atoms. In some cases, the non-sulfate-based anionic surfactant contains an alkyl and / or acyl group having more than 26 carbons.

[0034] The anionic surfactant may be selected from taurate surfactants having a structure according to the following formula:

[0035]

[0036] Where R 1 is a saturated or unsaturated, linear or branched alkyl chain having 6 to 18 carbon atoms, R 2 is H or methyl, and M + is H, sodium, or potassium (e.g., sodium methyl cocoyl taurate or sodium methyl oleoyl taurate).

[0037] Additional examples of taurate surfactants include sodium cocoyl taurate, potassium cocoyl taurate, potassium methyl cocoyl taurate, sodium caproyl methyl taurate, sodium cocoyl taurate, sodium lauroyl taurate, sodium methyl cocoyl taurate (SMCT), sodium methyl lauroyl taurate, sodium methyl myristoyl taurate, sodium methyl oleoyl taurate, sodium methyl palmitoyl taurate, sodium methyl stearoyl taurate, and combinations of two or more thereof. In some embodiments, the personal care composition comprises sodium lauroyl methyl taurate (or sodium methyl lauroyl taurate), sodium methyl cocoyl taurate (SMCT), or a combination thereof. In at least one preferred embodiment, the surfactant system comprises sodium methyl cocoyl taurate.

[0038] The limiting examples of isethionate surfactants include sodium isethionate, sodium cocoyl isethionate, sodium lauroyl methyl isethionate and sodium cocoyl methyl isethionate. Sulfonated fatty acid monoglycerides include sodium coconut oil monoglyceride sulfonate etc. The example of sarcosinate surfactants includes potassium lauroyl sarcosinate, potassium cocoyl sarcosinate, sodium cocoyl sarcosinate, sodium lauroyl sarcosinate, sodium myristoyl sarcosinate, sodium oleoyl sarcosinate, sodium palmitoyl sarcosinate, ammonium lauroyl sarcosinate and a combination of both or more thereof. The limiting examples of alkyl taurates include sodium cocoyl taurate, sodium methyl cocoyl taurate, oleoyl taurate. In at least one embodiment, the personal care composition includes one or more anionic surfactants containing oleoyl taurate and / or its salt.

[0039] Non-limiting examples of alkyl sulfosuccinates include disodium oleamido MIPA sulfosuccinate, disodium oleamido MEA sulfosuccinate, disodium lauryl sulfosuccinate, disodium laureth sulfosuccinate, diammonium lauryl sulfosuccinate, diammonium laureth sulfosuccinate, sodium dioctyl sulfosuccinate, disodium oleamido EMA sulfosuccinate, sodium dialkyl sulfosuccinates, or a combination of two or more thereof.

[0040] Non-limiting examples of alkyl sulfoacetates include, for example, alkyl sulfoacetates such as C 4 -C 18 Fatty alcohol sulfoacetate and / or its salt. The preferred sulfoacetate is sodium lauryl sulfoacetate. Useful cations for the salt include alkali metal ions such as sodium or potassium, ammonium, or alkanolammonium ions such as monoethanolammonium or triethanolammonium.

[0041] Examples of alkoxylated monobasic acids include, but are not limited to, butylphenol ether-5 carboxylic acid, butylphenol ether-19 carboxylic acid, octanol polyether-4 carboxylic acid, octanol polyether-6 carboxylic acid, octanol polyether-9 carboxylic acid, ceteareth-25 carboxylic acid, cocoeth-7 carboxylic acid, C 9-11 Pareth-6 Carboxylic Acid, C 11-15 Pareth-7 Carboxylic Acid, C 12-13 Pareth-5 Carboxylic Acid, C 12-13 Pareth-8 Carboxylic Acid, C 12-13 Alkyl polyether-12 carboxylic acid, C 12-15 Pareth-7 Carboxylic Acid, C 12-15 Pareth-8 Carboxylic Acid, C 14-15 Pareth-8 carboxylic acid, deceth-7 carboxylic acid, laureth-3 carboxylic acid, laureth-4 carboxylic acid, laureth-5 carboxylic acid, laureth-6 carboxylic acid, laureth-8 carboxylic acid, laureth-10 carboxylic acid, laureth-11 carboxylic acid, laureth-12 carboxylic acid, laureth-13 carboxylic acid, laureth-14 carboxylic acid, laureth-17 carboxylic acid, PPG-6-laureth-6 carboxylic acid, ppg-8-steareth-7 carboxylic acid, myreth-3 carboxylic acid, myreth-5 carboxylic acid, nonoxynol-5 carboxylic acid, nonoxynol-8 carboxylic acid, nonoxynol-10 carboxylic acid, octane-3 carboxylic acid, octane-2 0 carboxylic acid, oleth-3 carboxylic acid, oleth-6 carboxylic acid, oleth-10 carboxylic acid, ppg-3-deceth-2 carboxylic acid, capryleth-2 carboxylic acid, ceteth-13 carboxylic acid, decetheth-2 carboxylic acid, hexeth-4 carboxylic acid, isosteareth-6 carboxylic acid, isosteareth-11 carboxylic acid, trideceth-3 carboxylic acid, trideceth-6 carboxylic acid, trideceth-8 carboxylic acid, trideceth-12 carboxylic acid, trideceth-3 carboxylic acid, trideceth-4 carboxylic acid, trideceth-7 carboxylic acid, trideceth-15 carboxylic acid, trideceth-19 carboxylic acid, undeceth-5 carboxylic acid, and combinations of two or more thereof.

[0042] The non-sulfate-based anionic surfactant can be present in the personal care composition in an amount of about 0.3 wt % to about 10 wt %, based on the total weight of the personal care composition. For example, the personal care composition can include the non-sulfate-based anionic surfactant in an amount ranging from about 0.3 wt % to about 8 wt %, from about 0.3 wt % to about 6 wt %, from about 0.3 wt % to about 4 wt %, from about 0.3 wt % to about 3 wt %, from about 0.3 wt % to about 2 wt %; from about 0.5 wt % to about 10 wt %, from about 0.5 wt % to about 8 wt %, from about 0.5 wt % to about 6 wt %, from about 0.5 wt % to about 4 wt %, from about 0.5 wt % to about 3 wt %, from about 0.5 wt % to about 2 wt %; from about 1 wt % to about 10 wt %, from about 1 wt % to about 8 wt %, from about 1 wt % to about 6 wt %, from about 1 wt % to about 4 wt %, from about 1 wt % to about 3 wt %, from about 1 wt % to about From about 2 wt % to about 10 wt %, from about 1.5 wt % to about 8 wt %, from about 1.5 wt % to about 6 wt %, from about 1.5 wt % to about 4 wt %, from about 1.5 wt % to about 3 wt %; from about 2 wt % to about 10 wt %, from about 2 wt % to about 8 wt %, from about 2 wt % to about 6 wt %, from about 2 wt % to about 4 wt %, from about 2 wt % to about 3 wt %; from about 3 wt % to about 10 wt %, from about 3 wt % to about 8 wt %, from about 3 wt % to about 6 wt %, from about 3 wt % to about 4 wt %; from about 4 wt % to about 10 wt %, from about 4 wt % to about 8 wt %, from about 4 wt % to about 6 wt %; from about 5 wt % to about 10 wt %, from about 5 wt % to about 8 wt %, from about 5 wt % to about 6 wt %, or any range or subrange thereof. In certain embodiments, the non-sulfate based anionic surfactant may be present in the personal care composition in an amount of about 1 wt%, about 2 wt%, 3 wt%, about 4 wt%, about 5 wt%, or about 6 wt%, based on the total weight of the personal care composition.

[0043] Surfactant system can also comprise one or more amphoteric surfactants. Amphoteric surfactants are usually characterized by a combination of high surfactant activity, foam formation and mildness. Amphoteric surfactants can comprise a substituent such as an alkyl or acyl group containing 8 to 18 carbon atoms, and / or a substituent containing one or more carboxyl radicals, sulfonate radicals, sulfate radicals, phosphate radicals or phosphonate radicals. For example, amphoteric surfactants can have an alkyl radical containing 8 to 20 carbon atoms, 8 to 16 carbon atoms, 10 to 16 carbon atoms or 10 to 13 carbon atoms. Amphoteric surfactants can include but are not limited to derivatives of aliphatic secondary amines and tertiary amines, wherein aliphatic groups can be straight or branched, and wherein one of the aliphatic substituents comprises approximately 8 to approximately 18 carbon atoms, and one comprises an anionic water-soluble group, such as carboxyl, sulfonate radicals, sulfate radicals, phosphate radicals or phosphonate radicals.

[0044] Amphoteric surfactants can include amphoteric propionate surfactants, betaine surfactants, sulfobetaine surfactants, alkyl amphoteric acetate surfactants, and combinations of two or more thereof. In some cases, the personal care composition comprises one or more alkyl amphoteric propionates. Non-limiting examples of alkyl amphoteric propionate surfactants include cocoamphopropionate, cornamphopropionate, caprylamphopropionate, cornamphopropionate, caproamphopropionate, oleoamphopropionate, isostearylamphopropionate, stearoamphopropionate, lauroamphopropionate, salts thereof, and mixtures thereof. In one embodiment, the alkyl amphoteric propionate surfactant includes sodium cocoamphopropionate.

[0045] The personal care composition may include an amphoteric surfactant selected from betaine surfactants (also referred to as betaines). Examples of betaine surfactants include, but are not limited to, higher alkyl betaines such as cocodimethyl carboxymethyl betaine, lauryl dimethyl carboxy-methyl betaine, lauryl dimethyl α-carboxyethyl betaine, hexadecyl dimethyl carboxymethyl betaine, lauryl bis-(2-hydroxyethyl) carboxymethyl betaine, stearyl bis-(2-hydroxypropyl) carboxymethyl betaine, oleyl dimethyl γ-carboxypropyl betaine, and lauryl bis-(2-hydroxypropyl) α-carboxyethyl betaine; sulfobetaines such as cocodimethyl sulfopropyl betaine, stearyl dimethyl sulfopropyl betaine; amidobetaines; amidosulfobetaines; and the like. Preferably, the betaine surfactant is selected from coco betaine, cocamidopropyl betaine, lauryl betaine, lauryl hydroxysultaine, lauryl dimethyl betaine, cocamidopropyl hydroxysultaine, behenyl betaine, capryl / capramidopropyl betaine, lauryl hydroxysultaine, stearyl betaine, and a combination of two or more thereof. In some embodiments, at least one betaine surfactant is selected from coco betaine, cocamidopropyl betaine, behenyl betaine, capryl / capramidopropyl betaine, and lauryl betaine, and a combination of two or more thereof. In other embodiments, the betaine surfactant is selected from cocamidopropyl betaine, lauryl dimethyl betaine, hexadecyl dimethyl betaine, and cocoamphodiacetate (e.g., disodium cocoamphodiacetate), and a combination of two or more thereof. In at least one embodiment, the personal care composition comprises disodium cocoamphodiacetate, cocamidopropyl betaine, or a combination thereof.

[0046] In some cases, the amphoteric surfactant can be selected as sultaine (also known as sulfobetaine) and hydroxysultaine such as cocamidopropyl hydroxysultaine. The sultaine can be an alkyl sultaine having 6 to 20 carbons, 8 to 18 carbons, 8 to 16 carbons, or 10 to 16 carbons. Non-limiting examples of alkyl sultaines include hydroxysultaines having a structure according to the formula:

[0047]

[0048] wherein R is an alkyl group having 8 to 18 carbon atoms. Examples of alkyl sultaine surfactants include, but are not limited to, cocamidopropyl hydroxysultaine, lauryl hydroxysultaine, and combinations of two or more thereof.

[0049] In some embodiments, the surfactant system comprises an amphoteric surfactant selected from the group consisting of a betaine surfactant and optionally an additional amphoteric surfactant other than betaine (including those discussed above). The one or more betaine surfactants may preferably be selected from the group consisting of coco betaine, cocamidopropyl betaine, lauryl betaine, lauryl hydroxysultaine, lauryl dimethyl betaine, cocamidopropyl hydroxysultaine, behenyl betaine, capryloyl / capramidopropyl betaine, lauryl hydroxysultaine, stearyl betaine, and combinations of two or more thereof.

[0050] In certain embodiments, at least one amphoteric surfactant can be present in the personal care composition in an amount that can vary, but generally ranges from about 1 wt % to about 26 wt %, based on the total weight of the personal care composition. For example, the total amount of amphoteric surfactant in the personal care composition can be from about 1 wt % to about 20 wt %, from about 1 wt % to about 19 wt %, from about 1 wt % to about 18 wt %, from about 1 wt % to about 15 wt %, from about 1 wt % to about 12 wt %, from about 5 wt % to about 10 wt %; from about 5 wt % to about 20 wt %, from about 5 wt % to about 19 wt %, from about 1 wt % to about 18 wt %, from about 1 wt % to about 15 wt %, from about 1 wt % to about 12 wt %, from about 5 wt % to about 10 wt %; % to about 12 wt %; about 10 wt % to about 20 wt %; about 10 wt % to about 19 wt %, about 10 wt % to about 18 wt %, about 10 wt % to about 15 wt %, about 10 wt % to about 12 wt %; about 15 wt % to about 20 wt %; about 16 wt % to about 20 wt %, about 17 wt % to about 20 wt %, about 18 wt % to about 20 wt %, about 18 wt % to about 19 wt %, about 19 wt % to about 20 wt %, or any range or sub-range thereof. In certain embodiments, one or more amphoteric surfactants are present in an amount ranging from about 1 wt % to about 5 wt %, for example, from about 3 wt % to about 4 wt %, based on the total weight of the personal care composition. In certain embodiments, the one or more amphoteric surfactants are present in an amount of about 12 wt %, about 13 wt %, about 14 wt %, about 15 wt %, about 16 wt %, about 17 wt %, about 18 wt %, about 19 wt %, or about 20 wt %, based on the total weight of the personal care composition.

[0051] The surfactant system may include at least one nonionic surfactant. The at least one nonionic surfactant may be selected from glycoside surfactants, glucoside surfactants, glyceride surfactants, compounds produced by condensation of oxyalkylene groups (hydrophilic in nature) with organic hydrophobic compounds that may be aliphatic or alkyl aromatic in nature, and combinations of two or more thereof. Preferably, at least one nonionic surfactant is selected from glycoside surfactants, glucoside surfactants, glyceride surfactants, and combinations of two or more thereof. In some embodiments, the personal care composition comprises two or more (e.g., 2, 3, 4, or 5) nonionic surfactants.

[0052] The surfactant system may include at least one nonionic glyceride surfactant selected from the following: glyceryl monostearate, oleyl glyceride, linoleyl glyceride, ricinoleic acid glyceride, PEG oleic acid glyceride, PCA oleic acid glyceride, and a combination of two or more thereof. In at least one embodiment, PEG oleic acid glyceride may be PEG-18 oleic acid glyceride. Examples of glucoside surfactants include decyl glucoside, stearyl glucoside, lauryl glucoside, coconut oil glucoside, cetearyl glucoside, decyl lauryl glucoside, lauroyl ethyl glucoside, myristoyl ethyl glucoside, oleoyl ethyl glucoside, or a combination of two or more thereof. In some embodiments, the surfactant system includes one or more nonionic surfactants selected from the following: lauryl glucoside, lauroyl ethyl glucoside, myristoyl ethyl glucoside, oleoyl ethyl glucoside, and a combination of two or more thereof. Additionally or alternatively, the glucoside surfactant may be selected from polyglucosides, such as alkyl polyglycosides.

[0053] Other examples of nonionic surfactants include: poloxamers; polyethylene oxide condensates of alkylphenols; products derived from the condensation of ethylene oxide with the reaction product of propylene oxide and ethylenediamine; ethylene oxide condensates of aliphatic alcohols, acids and esters; long-chain tertiary amine oxides; long-chain tertiary phosphine oxides; long-chain dialkyl sulfoxides and mixtures of such substances. Other examples of nonionic surfactants include polyoxyethylene, polyoxyethylene sorbitan esters, polyoxyethylene 40 hydrogenated castor oil, fatty alcohol ethoxylates, polyethylene oxide condensates of alkylphenols, products derived from the condensation of ethylene oxide with the reaction product of propylene oxide and ethylenediamine, ethylene oxide condensates of aliphatic alcohols, long-chain tertiary amine oxides, long-chain tertiary phosphine oxides, long-chain dialkyl sulfoxides, or a combination of two or more thereof. In some cases, the nonionic surfactant includes amine oxides, fatty acid amides, ethoxylated fatty alcohols, block copolymers of polyethylene glycol and polypropylene glycol, glycerol alkyl esters, polyethylene glycol octylphenol ethers, sorbitan alkyl esters, polyethylene glycol sorbitan alkyl esters, or a combination of two or more thereof.

[0054] In at least one embodiment, the nonionic surfactant comprises PEG methyl glucose dioleate. The PEG methyl glucose dioleate can be PEG-120 methyl glucose dioleate. In certain embodiments, the personal care compositions disclosed herein are free or substantially free of PEG and any PEG-derived surfactants or thickeners.

[0055] At least one nonionic surfactant can be present in an amount of about 1 wt % to about 12 wt %, based on the total weight of the personal care composition. In some cases, at least one nonionic surfactant is present in the surfactant system in an amount of about 1 wt % to about 10 wt %, about 1 wt % to about 8 wt %, about 1 wt % to about 6 wt %, about 1 wt % to about 5 wt %, about 1 wt % to about 4 wt %; about 2 wt % to about 12 wt %, about 2 wt % to about 10 wt %, about 2 wt % to about 8 wt %, about 2 wt % to about 6 wt %, about 2 wt % to about 5 wt %, about 2 wt % to about 4 wt %; about 3 wt % to about 12 wt %, about 3 wt % to about 12 wt %, about 3 wt % to about 10 wt % , about 3 wt % to about 8 wt %, about 3 wt % to about 6 wt %, about 3 wt % to about 5 wt %, about 3 wt % to about 4 wt %; about 4 wt % to about 12 wt %, about 4 wt % to about 10 wt %, about 4 wt % to about 8 wt %, about 4 wt % to about 7 wt %, about 4 wt % to about 6 wt %; about 5 wt % to about 12 wt %, about 5 wt % to about 10 wt %, about 5 wt % to about 8 wt %, about 5 wt % to about 7 wt %; about 6 wt % to about 12 wt %, about 6 wt % to about 10 wt %, about 6 wt % to about 8 wt %, about 7 wt % to about 11 wt %, or any range or subrange thereof.

[0056] The personal care composition can be formulated to have a surfactant system having a total amount of nonionic surfactants and amphoteric surfactants in a specific weight ratio. For example, the surfactant system can have a total amount of nonionic surfactants and amphoteric surfactants weight ratio ranging from about 1.5: 1 to about 7: 1. In some embodiments, the personal care composition has a total amount of nonionic surfactants and amphoteric surfactants weight ratio ranging from about 1.5: 1 to about 6: 1, about 2: 1 to about 6: 1, about 3: 1 to about 6: 1, about 4: 1 to about 6: 1; about 4.5: 1 to about 6: 1, about 4: 1 to about 5: 1, about 4.5: 1, about 4.6: 1, about 4.7: 1, about 4.8: 1, about 4.9: 1, about 5: 1, about 5.5: 1, about 5.6: 1, about 5.7: 1, about 5.8: 1, or about 5.9: 1, or any range or sub-range thereof.

[0057] The personal care composition can be formulated to have a surfactant system having a specific weight ratio of the total amount of anionic surfactant to the total amount of amphoteric surfactant. For example, in some preferred embodiments, the personal care composition has a weight ratio of non-sulfate based anionic surfactant to amphoteric surfactant in the range of: from about 2:1 to about 1:9, from about 1:2 to about 1:8, from about 1:2 to about 1:7, from about 1:2 to about 1:6.5, from about 1:2 to about 1:6; from about 1:3 to about 1:9, from about 1:3 to about 1:8, from about 1:3 to about 1:7, from about 1:3 to about 1:6.5, from about 1:3 to about 1:6; from about 1:3.5 to about 1:9, from about 1:3.5 to about 1:8, from about 1:3.5 to about 1:7, from about 1:3.5 to about 1:6.5, from about 1:3.5 to about 1:6; from about 1:4 to about 1:9, from about 1:4 to about 1:8, from about 1:4 to about 1:7, from about 1:4 to about 1:6.5, from about 1:4 to about 1:6, or any range or sub-range thereof.

[0058] The personal care composition disclosed herein may also include at least one tear film protectant. As used herein, the term "tear film protectant" means an ingredient that can reduce irritation to the eyes. In certain embodiments, the at least one tear film protectant is selected from ingredients that are gentle and soft to the eyes, including all-natural ingredients. The human eye contains a thin liquid layer (called a tear film) covering the outer surface of the eye. The tear film is a fluid of about 3 μL forming a layer of about 3 μm thick. The tear film includes two layers (aqueous layer and a lipid layer). While the lipid layer is used to prevent tears from evaporating from the surface of the eye, the aqueous layer is responsible for forming most of the tears, which is used to provide oxygen and nutrients to the eyes and remove unwanted debris. In certain embodiments, the personal care composition includes at least two tear film protectants, such as at least one hydrophilic tear film protectant for protecting the aqueous layer of the tear film and at least one hydrophobic tear film protectant for protecting the lipid layer of the tear film.

[0059] In certain embodiments, at least one tear film protective agent is hydrophilic and includes a polyol. The polyol may be selected from a diol or a compound having a plurality of hydroxyl groups. In some cases, one or more polyols are selected from C 2 -C 32Polyols. One or more polyols can be liquid at ambient temperature (25°C). One or more polyols can have 2 to 32 carbon atoms, 3 to 16 carbon atoms, or 3 to 12 carbon atoms. In some cases, the polyols that can be included in the personal care composition include ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, glycerol, diglycerol, diethylene glycol and dipropylene glycol, and mixtures thereof. In some cases, the personal care composition comprises glycerol and optionally one or more polyols other than glycerol. Non-limiting examples of polyols that may be optionally included in the personal care include and / or may be selected from alkanediols such as glycerol, 1,2,6-hexanetriol, trimethylolpropane, ethylene glycol, propylene glycol, butylene glycol, pentanediol, hexanediol, diethylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol, 2-butene-1,4-diol, 2-ethyl-1,3-hexanediol, 2-methyl-2,4-pentanediol, octylene glycol, 1,2-hexanediol, 1,2-pentanediol, and 4-methyl-1,2-pentanediol; glycol ethers such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether , ethylene glycol monobutyl ether, ethylene glycol monomethyl ether acetate, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol mono-n-propyl ether, ethylene glycol monoisopropyl ether, diethylene glycol monoisopropyl ether, ethylene glycol mono-n-butyl ether, ethylene glycol mono-tert-butyl ether, diethylene glycol mono-tert-butyl ether, 1-methyl-1-methoxybutanol, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol mono-tert-butyl ether, propylene glycol mono-n-propyl ether, propylene glycol monoisopropyl ether, dipropylene glycol monomethyl ether, dipropylene glycol monoethyl ether, dipropylene glycol mono-n-propyl ether, dipropylene glycol monoisopropyl ether, sorbitol, sorbitan, glyceryl triacetate; and mixtures thereof.

[0060] In certain embodiments, at least one tear film protective agent is hydrophilic, and in certain embodiments, at least one tear film protective agent is glycerol. In certain embodiments, at least one hydrophilic tear film protective agent such as glycerol is present in the personal care composition in an amount ranging from about 1 wt % to about 30 wt %, based on the total weight of the personal care composition. For example, based on the total weight of the personal care composition, the total amount of polyols in the personal care composition can be from about 1 wt % to about 25 wt %, from about 1 wt % to about 22 wt %, from about 1 wt % to about 18 wt %, from about 1 wt % to about 12 wt %, from about 1 wt % to about 8 wt %, from about 1 wt % to about 6 wt %, from about 1 wt % to about 5 wt %, from about 1 wt % to about 4 wt %, from about 1 wt % to about 3 wt %; from about 2 wt % to about 30 wt %, from about 2 wt % to about 25 wt %, from about 2 wt % to about 22 wt %, from about 2 wt % to about 18 wt %, from about 2 wt % to about 1 ...8 wt %, from about 2 wt % to about 12 wt %, from about 2 % to about 8 wt %, about 2 wt % to about 6 wt %, about 2 wt % to about 5 wt %, about 2 wt % to about 4 wt %, about 2 wt % to about 3 wt %; about 3 wt % to about 22 wt %, about 3 wt % to about 18 wt %, about 3 wt % to about 12 wt %, about 3 wt % to about 8 wt %, about 3 wt % to about 6 wt %, about 3 wt % to about 5 wt %; about 5 wt % to about 25 wt %, about 5 wt % to about 22 wt %, about 5 wt % to about 20 wt %, about 5 wt % to about 18 wt %, about 5 wt % to about 16 wt %, about 5 wt % to about 12 wt %, about 5 wt % to about 10 wt %. % by weight, about 5 wt % to about 8 wt %; about 7 wt % to about 30 wt %, about 7 wt % to about 25 wt %, about 7 wt % to about 22 wt %, about 7 wt % to about 20 wt %, about 7 wt % to about 18 wt %, about 7 wt % to about 16 wt %; about 9 wt % to about 30 wt %, about 9 wt % to about 25 wt %, about 9 wt % to about 22 wt %, about 9 wt % to about 20 wt %, about 9 wt % to about 18 wt %, about 9 wt % to about 16 wt %; about 12 wt % to about 30 wt %, about 12 wt % to about 25 wt %, about 12 wt % to about 22 wt %, about 12 wt % to about % to about 20 weight %, about 12 weight % to about 18 weight %, about 12 weight % to about 16 weight %; about 14 weight % to about 30 weight %, about 14 weight % to about 25 weight %, about 14 weight % to about 22 weight %, about 14 weight % to about 20 weight %, about 14 weight % to about 18 weight %; about 16 weight % to about 30 weight %, about 16 weight % to about 25 weight %, about 16 weight % to about 22 weight %, about 16 weight % to about 20 weight %; about 18 weight % to about 30 weight %, about 18 weight % to about 25 weight %, about 21 weight % to about 25 weight %, or any range or sub-range thereof.

[0061] In certain embodiments, at least one tear film protective agent can be a hydrophobic agent. In certain embodiments, at least one hydrophobic tear film protective agent is selected from glyceride surfactants, such as monostearate, oleate, linoleate, ricinoleate, PEG oleate, PCA oleate, and combinations of two or more thereof. In certain embodiments, at least one tear film protective agent is oleate. In certain embodiments, oleate can be used as an additional ingredient or mixture of ingredients (e.g., in the form of glyceryl monostearate, available from BASF). A portion of the ingredients in the form of PO-65 is added to the composition together.

[0062] In certain embodiments, at least one hydrophobic tear film protective agent can be present in the personal care composition in an amount ranging from about 0.1 wt % to about 7 wt %, for example, from about 0.1 wt % to about 5 wt %, from about 0.1 wt % to about 4 wt %, from about 0.1 wt % to about 3 wt %, from about 0.1 wt % to about 2 wt %, from about 0.1 wt % to about 1 wt % based on the total weight of the personal care composition; from about 0.5 wt % to about 75 wt %, from about 0.5 wt % to about 5 wt %, from about 0.5 wt % to about 4 wt %, from about 0.5 wt % to about 3 wt %, from about 0.1 wt % to about 2 wt %, from about 0.1 wt % to about 1 wt %; % to about 3 weight %, about 0.5 weight % to about 2 weight %, about 0.5 weight % to about 1 weight %; about 1 weight % to about 7 weight %, about 1 weight % to about 5 weight %, about 1 weight % to about 4 weight %, about 1 weight % to about 3 weight %, about 1 weight % to about 2 weight %; about 2 weight % to about 7 weight %, about 2 weight % to about 5 weight %, about 2 weight % to about 4 weight %, about 2 weight % to about 3 weight %; about 3 weight % to about 7 weight %, about 3 weight % to about 5 weight %, about 3 weight % to about 4 weight %, or any range or sub-range thereof.

[0063] In certain embodiments, the personal care compositions comprise at least one hydrophilic tear film protectant (eg, glycerin) and at least one hydrophobic tear film protectant (eg, glyceryl oleate).

[0064] The personal care composition may optionally include at least one thickening agent, and in certain embodiments, the personal care composition may be substantially free of or free of at least one thickening agent, wherein the thickening agent is not part of the surfactant system. If present, the amount of thickening agent in the personal care composition may be from about 0.1% to about 7% by weight, from about 0.1% to about 5% by weight, from about 0.1% to about 4% by weight, from about 0.1% to about 3% by weight, from about 0.1% to about 2% by weight, from about 0.1% to about 1% by weight, based on the total weight of the personal care composition; from about 0.5% to about 7% by weight, from about 0.5% to about 5% by weight, from about 0.5% to about 4% by weight, from about 0.5% to about 3% by weight, from about 0.1% to about 2% by weight, from about 0.1% to about 1% by weight; from about 0.5% to about 7% by weight, from about 0.5% to about 5% by weight, from about 0.5% to about 4% by weight, from about 0.5% to about 3% by weight, from about 0. 5 wt % to about 2 wt %, about 0.5 wt % to about 1 wt %; about 1 wt % to about 7 wt %, about 1 wt % to about 5 wt %, about 1 wt % to about 4 wt %, about 1 wt % to about 3 wt %, about 1 wt % to about 2 wt %; about 2 wt % to about 7 wt %, about 2 wt % to about 5 wt %, about 2 wt % to about 4 wt %, about 2 wt % to about 3 wt %; about 3 wt % to about 7 wt %, about 3 wt % to about 5 wt %, about 3 wt % to about 4 wt %, or any range or sub-range thereof.

[0065] Without being limited to any particular theory, the personal care compositions in some embodiments achieve a preferred viscosity with a minimum amount or when substantially free of or free of thickeners (e.g., thickeners other than surfactants). For example, based on the gross weight of the personal care composition, the personal care composition may contain a thickener in an amount of about 0.1 wt%, about 0.5 wt%, about 1 wt%, about 2 wt%, about 3 wt%, or about 3.5 wt%, up to about 1 wt%, up to about 2 wt%, up to about 3 wt%, up to about 4 wt%, or up to about 5 wt% (including any range or sub-range formed thereby). In some embodiments, based on the gross weight of the personal care composition, the personal care composition may have a total amount of about 5 wt% or less, about 4 wt% or less, about 3 wt% or less, about 2 wt% or less, about 1 wt% or less, about 0.5 wt% or less, or about 0.1 wt% or less of thickener. In some preferred embodiments, the personal care composition does not contain a thickener other than the thickener constituting the surfactant.

[0066] Thickening agents may be referred to as "thickeners" or "viscosity modifiers". Thickeners are typically included to increase the viscosity of personal care compositions. Non-limiting examples of thickeners that may be incorporated into or excluded from personal care compositions include natural gums, polyacrylate cross-linked polymers or cross-linked polyacrylate polymers, cationic acrylate copolymers, anionic acrylic acid or carboxylic acid polymers, polyacrylamide polymers, polysaccharides (e.g., cellulose derivatives), cationic gums, polyquaternium salts, vinyl pyrrolidone homopolymers / copolymers, C 8-24 Hydroxyl substituted aliphatic acid, C 8-24 Conjugated aliphatic acids, sugar fatty esters, polyglycerol esters and mixtures thereof. Particular types of thickeners that may be mentioned include the following: gums (e.g. natural gums, xanthan gum), sucrose esters, polyvinylpyrrolidone (PVP) and copolymers, celluloses, polyquaternium compounds and homopolymers or copolymers based on carboxylic acids or carboxylic acid esters, which may be linear or crosslinked.

[0067] In some embodiments, the personal care composition is substantially free or free of acrylate-based thickeners. For example, the personal care composition can be formulated to have about 6 wt % or less, about 4 wt % or less, about 3 wt % or less, about 2 wt % or less, about 1 wt % or less, about 0.5 wt % or less, or about 0.1 wt % or less of acrylate-based thickeners, based on the total weight of the personal care composition. In at least one embodiment, the personal care composition is free of acrylate-based thickeners.

[0068] Additionally or alternatively, the personal care composition can be substantially free or free of polymer-based thickeners. For example, the personal care composition can be formulated to have about 6 wt % or less, about 4 wt % or less, about 3 wt % or less, about 2 wt % or less, about 1 wt % or less, about 0.5 wt % or less, or about 0.1 wt % or less of a polymer-based thickener, based on the total weight of the personal care composition. In at least one embodiment, the personal care composition is free of polymer-based thickeners.

[0069] The personal care composition can also be substantially free or free of polysaccharide-based thickeners. For example, the personal care composition can be formulated to have about 6 wt % or less, about 4 wt % or less, about 3 wt % or less, about 2 wt % or less, about 1 wt % or less, about 0.5 wt % or less, or about 0.1 wt % or less of a polysaccharide-based thickener, based on the total weight of the personal care composition. In at least one embodiment, the personal care composition is free of polysaccharide-based thickeners.

[0070] Additionally or alternatively, the personal care composition can be substantially free of or free of thickener (e.g., in addition to thickeners that constitute the surfactant). For example, the personal care composition can be formulated to have about 6 wt % or less, about 4 wt % or less, about 3 wt % or less, about 2 wt % or less, about 1 wt % or less, about 0.5 wt % or less, or about 0.1 wt % or less of thickener (e.g., in addition to thickeners that constitute the surfactant), based on the gross weight of the personal care composition. In at least one embodiment, the personal care composition is free of thickener.

[0071] In certain embodiments, the personal care composition disclosed herein may also include at least one anti-irritant and / or at least one anti-allergic agent. Exemplary anti-irritants or anti-allergic agents may include, for example, dipropylene glycol (DPG), methyl salicylate, capsaicin, eugenol, menthol, wintergreen oil, camphor, eucalyptus, eucalyptol, mustard cream, turpentine, safrole (safrol), menthyl lactate, ethoxy menthyl acetate, menthone glycerol acetal, 3-1-menthoxy propane-1,2-diol, ethyl 1-menthyl carbonate, (1S, 3S, 4R)-p-menthyl-8-ene-3-ol, menthyl pyrrolidone carboxylate, N-substituted p-menthane-3-carboxamide, ketal coolants (including, for example, 1-menthone-1d-isomenthone glycerol ketal). Other examples of agents with soothing properties that may encompass at least one anti-irritant or at least one anti-allergic agent include, but are not limited to, herbal extracts such as aloe, alpha-bisabolol, D-panthenol, allantoin, witch hazel, chamomile, yarrow; vitamins such as tocopheryl acetate (vitamin E); calendula, comfrey, witch hazel and other astringents, seaweed and oat extracts; oils such as almond oil, avocado oil and comfrey; and essential oils such as cardamone, eucalyptus, mentha piperita (peppermint), hyssop and rosemary; waxy or oily substances such as lanolin or petrolatum jelly; minerals such as zinc oxide, calamine and selenium; and combinations thereof.

[0072] At least one anti-irritant and / or at least one anti-allergic agent can be present in the personal care composition in any amount sufficient to provide an anti-irritant effect and / or an anti-allergic effect to the user, such as, for example, in an amount ranging from about 0.1% to about 5% by weight based on the total weight of the personal care composition. For example, the personal care composition can be formulated to have at least one anti-irritant and / or at least one anti-allergic agent present in an amount ranging from about 0.1% to about 4% by weight, from about 0.1% to about 3% by weight, from about 0.1% to about 2% by weight; from about 1% to about 4% by weight, from about 1% to about 3% by weight, from about 1% to about 2% by weight; from about 2% to about 4% by weight, from about 2% to about 3% by weight; from about 3% to about 4% by weight, or any range or sub-range thereof, based on the total weight of the personal care composition.

[0073] In certain embodiments, the personal care composition comprises a salt in an amount ranging from about 0.1% to about 4.5% by weight, based on the total weight of the personal care composition. For example, the personal care composition can be formulated to have a salt present in the following amounts: from about 0.1% to about 4.5% by weight, from about 0.1% to about 4% by weight, from about 0.1% to about 3.5% by weight, from about 0.1% to about 3% by weight, from about 0.1% to about 2.5% by weight, from about 0.1% to about 2% by weight; from about 0.5% to about 4.5% by weight, from about 0.5% to about 4.5% by weight, from about 0.5% to about 3.5% by weight, from about 0.1% to about 3% by weight, from about 0.1% to about 2.5% by weight, from about 0.1% to about 2% by weight; .5 wt %, about 1 wt % to about 3 wt %, about 1 wt % to about 2.5 wt %, about 1 wt % to about 2 wt %; about 1.5 wt % to about 4.5 wt %, about 1.5 wt % to about 4 wt %, about 1.5 wt % to about 3.5 wt %, about 1.5 wt % to about 3 wt %, about 1.5 wt % to about 2.5 wt %; about 2 wt % to about 4.5 wt %, about 2 wt % to about 4 wt %, about 2 wt % to about 3.5 wt %, about 2 wt % to about 3 wt %; about 2.5 wt % to about 4.5 wt %, about 2.5 wt % to about 4 wt %, about 2.5 wt % to about 3.5 wt %; about 3 wt % to about 4.5 wt %, about 3 wt % to about 4.5 wt %, or any range or sub-range thereof. The salt can be an inorganic salt, such as sodium chloride, sodium sulfate, calcium chloride, potassium chloride, or a combination thereof.

[0074] The personal care composition can be formulated to have a viscosity of from about 3,000 cP to about 15,000 cP in undiluted form using a Brookfield DV2T viscometer with a No. 5 spindle at 20 RPM and a temperature of 25°C. In some cases, the use of the personal care composition Brookfield The viscosity of the DV2T viscometer with a No. 5 spindle at 20 RPM and a temperature of 25°C is about 3,000 cP to about 15,000 cP, about 3,000 cP to about 12,000 cP, about 3,000 cP to about 10,000 cP, about 3,000 cP to about 8,000 cP, about 3,000 cP to about 7,000 cP, about 3,000 cP to about 6,000 cP; about 3,500 cP to about 15,000 cP, about 3,500 cP to about 12,000 cP, about 3,500 cP to about 10,000 cP, about 3,500 cP to about 8,000 cP, about 3,500 cP to about 7,000 cP, about 3,500 cP to about 6,000 cP; about 6,000 cP; about 4,000 cP to about 15,000 cP, about 4,000 cP to about 12,000 cP, about 4,000 cP to about 10,000 cP, about 4,000 cP to about 8,000 cP, about 4,000 cP to about 7,000 cP, about 4,000 cP to about 6,000 cP; about 4,500 cP to about 15,000 cP, about 4,500 cP to about 12,000 cP, about 4,500 cP to about 10,000 cP, about 4,500 cP to about 8,000 cP, about 4,500 cP to about 7,000 cP, about 4,500 cP to about 6,000 cP, or any range or sub-range thereof.

[0075] Personal care compositions typically include water. Water can be present in the personal care composition in an amount ranging from about 45% to about 94% by weight, based on the total weight of the personal care composition. For example, based on the total weight of the personal care composition, the personal care composition can include water in the following amounts: from about 55% to about 94% by weight, from about 65% to about 94% by weight, from about 68% to about 94% by weight, from about 71% to about 94% by weight, from about 75% to about 94% by weight, from about 78% to about 94% by weight, from about 81% to about 94% by weight, from about 84% to about 94% by weight; from about 45% to about 91% by weight, ...55% to about 94% by weight, from about 55% to about 94% by weight, from about 55% to about 94% by weight, from about 55% to about 94% by weight, from about 55% to about 94% by weight, from about 55% to about 94% by weight, from about 55% to about 94% by weight, from about 55% to about 94% by weight, from about 55% to about 94% by weight, from about % to about 91 wt %, about 65 wt % to about 91 wt %, about 68 wt % to about 91 wt %, about 71 wt % to about 91 wt %, about 75 wt % to about 91 wt %, about 78 wt % to about 91 wt %, about 81 wt % to about 91 wt %; about 45 wt % to about 88 wt %, about 55 wt % to about 88 wt %, about 65 wt % to about 88 wt %, about 68 wt % to about 8 ...88 wt %, about 7 5 wt % to about 88 wt %, about 78 wt % to about 88 wt %; about 45 wt % to about 85 wt %, about 55 wt % to about 85 wt %, about 65 wt % to about 85 wt %, about 68 wt % to about 85 wt %, about 71 wt % to about 85 wt %, about 75 wt % to about 85 wt %, about 78 wt % to about 85 wt %; about 45 wt % to about 82 wt %, about 55 wt % to about 82 wt %, about 65 wt % to about 82 wt %, From about 68 wt % to about 82 wt %, from about 71 wt % to about 82 wt %, from about 75 wt % to about 82 wt %; from about 45 wt % to about 79 wt %, from about 55 wt % to about 79 wt %, from about 65 wt % to about 79 wt %, from about 68 wt % to about 79 wt %; from about 45 wt % to about 76 wt %, from about 55 wt % to about 76 wt %, from about 65 wt % to about 76 wt %, from about 68 wt % to about 76 wt %, or any range or sub-range thereof.

[0076] The personal care compositions disclosed herein can be slightly acidic. For example, in certain embodiments, the personal care compositions disclosed herein have a pH in the range of 2 to 7, such as 3 to 6, or 4 to 5, or any range or subrange thereof. In certain embodiments, the personal care compositions disclosed herein have a pH greater than 3, such as a pH of 3.2, a pH of 3.5, a pH of 4, a pH of 4.2, a pH of 4.5, a pH of 5, a pH of 5.2, or a pH of 5.5.

[0077] The personal care composition may include one or more pH adjusting agents to increase or decrease the overall pH of the personal care composition. For example, one or more acids may be included to decrease the pH of the personal care composition. Examples of suitable acids for decreasing the pH of the personal care composition include, but are not limited to, citric acid, acetic acid, lactic acid, and the like. The personal care composition may include one or more bases such as sodium hydroxide, potassium hydroxide, and the like to increase the pH of the personal care composition. One of ordinary skill in the art will readily appreciate additional or alternative acids and bases suitable for adjusting the pH of the personal care composition.

[0078] The amount of pH adjusting agent in the personal care composition can be based on the desired pH of the final form of the personal care composition and / or product (e.g., in undiluted / concentrated form and / or in diluted / ready-to-use form). For example, the total amount of pH adjusting agent can range from about 0.05 wt % to about 20 wt % based on the gross weight of the personal care composition. In some cases, the total amount of pH adjusting agent is from about 0.05 wt % to about 15 wt %, from about 0.1 wt % to about 10 wt %, from about 0.1 wt % to about 1 wt %, from about 0.2 wt % to about 0.5 wt %, including ranges and sub-ranges therebetween, based on the gross weight of the personal care composition.

[0079] Personal care compositions generally include preservative systems. Preservative systems may include lactic acid, citric acid, sodium benzoate, potassium sorbate, salicylic acid, N,N-bis (carboxymethyl)-L-glutamate tetrasodium, its salt or a combination of two or more thereof. Preservative systems may include sodium lactate, sodium salicylate, calcium lactate and / or sodium citrate. In some embodiments, preservative systems include citric acid and / or its salt. In other embodiments, preservative systems include N,N-bis (carboxymethyl)-L-glutamate tetrasodium and at least one preservative selected from potassium sorbate, sodium benzoate, and a combination of two or more thereof. Additionally or alternatively, preservative systems may include lactic acid, N,N-bis (carboxymethyl)-L-glutamate tetrasodium and at least one preservative selected from potassium sorbate, sodium benzoate, and a combination of two or more thereof.

[0080] The personal care composition can also include one or more colorants. The colorant can be a pigment, a dye, or a mixture thereof. The non-limiting examples of pigments include titanium dioxide, zinc oxide, kaolin, mica, etc. The non-limiting examples of dyes include food dyes suitable for food, medicine and cosmetic applications, and mixtures thereof. Some pigments (colorants) are referred to as FD&C dyes. In some embodiments, based on the gross weight of the personal care composition, the colorant can be present in an amount ranging from about 0.0001 % by weight to about 0.4 % by weight (including all percentages and subranges therebetween). In other embodiments, based on the gross weight of the personal care composition, the colorant can be present in an amount ranging from about 0.0001 % by weight to about 4 % by weight (including all percentages and subranges therebetween).

[0081] The personal care compositions disclosed herein can be made using methods known in the art. Typically, the ingredients are combined and optionally heated where necessary to melt the components. The components are mixed. Desirably, volatile materials such as fragrance materials are incorporated into the composition in the later stages of the mixing cycle to prevent them from volatilizing. After mixing, the composition can be poured directly into a dispenser and the container capped to preserve the product until use.

[0082] In another aspect, the present disclosure provides a method of depositing a personal care composition as disclosed herein on the skin and / or hair, the method comprising applying an effective amount of the personal care composition disclosed herein to the skin and / or hair. The method further comprises optionally foaming the personal care composition, for example by generating foam in the presence or absence of water, and then optionally rinsing the personal care composition from the skin and / or hair (e.g., with water).

[0083] Example

[0084] Example 1

[0085] Four non-limiting exemplary personal care compositions (Example Compositions A, B, C, and D) were prepared and evaluated against a comparative formulation of a children's 3-in-1 bath gel product advertised as a "tear-free" formulation.

[0086] Composition A contained SLES and cocamidopropyl betaine surfactant system. Compositions B to D contained no SLES and contained the following surfactant systems:

[0087] Composition B: cocamidopropyl betaine, coco-glucoside, disodium cocoamphodiacetate (3.95%) and disodium 2-sulfolaurate;

[0088] Composition C: cocamidopropyl betaine, coco-glucoside, sodium methyl oleyl taurate and disodium 2-sulfolaurate; and

[0089] Composition D: Cocamidopropyl betaine, coco-glucoside, disodium cocoamphodiacetate (6.565%) and disodium 2-sulfolaurate.

[0090] The tear film protectant used in composition A was 5% glycerin, while the tear film protectants used in compositions B to C were 5% glycerin and 0.75% glyceryl oleate.

[0091] The formulations of Example Compositions A to D are shown in Table 1 below.

[0092] Table 1 - Summary of Test Compositions

[0093]

[0094] Example compositions A to D were evaluated for stability under 13 week accelerated aging conditions. The results of the stability studies are shown in Table 2 below.

[0095] Table 2 - Formulation stability studies

[0096]

[0097] Hand washing and SITA Foam Tester foam studies were conducted using a comparative product (Comparative #1) and a shower gel product (Comparative #2) as a benchmark. Comparative #1 contained the following ingredients: water; a surfactant system comprising cocamidopropyl betaine, sodium myreth sulfate, and decyl glucoside; sodium benzoate; glycerin; bisabolol; and a thickening system comprising PEG-200 hydrogenated glyceryl palmitate, guar hydroxypropyltrimonium chloride, and sodium chloride. Comparative Product #1 had a pH of about 4.5 and a viscosity of about 3700 cps (spindle 4, 20 rpm, 1 minute). Comparative Product #2 contained decyl glucoside and xanthan gum.

[0098] In the hand washing test, composition B performed best, followed by composition C, composition A, comparison #1, composition D, and comparison #2. In the SITA foam test, foam volume and bubble size were evaluated. Regarding foam volume, composition A had the highest foam volume, followed by composition B and composition C, all of which were better than composition D, comparison #1, and comparison #2. Comparison #1 showed a foam volume / mL of 835.5 and comparison #2 showed a foam volume / mL of 647.6. Compositions A, B, and C had foam volumes / mL of 873.6, 857.7, and 856.1, respectively, and composition D had a foam volume / mL of 621.5.

[0099] Example 2 - Human Eye Irritation (HEI) Test

[0100] HEI testing was performed on each of Compositions A to D and Comparative #1. Before and at the end of the HEI test, the eyes of all subjects were examined and graded by an ophthalmologist for the presence or absence of tearing, conjunctival irritation, and overall redness or hyperemia of the sclera. The parameters were evaluated on a scale of 0 to 4 as follows: (0) none; (0.5) very slight; (1) slight; (2) moderate; (3) marked; and (4) very severe. Visual acuity testing and evaluation was performed on each subject before and after the application of the drops. Additionally, the subjects were asked to rate the intensity or perceived discomfort of the drops within 10 seconds of application using the following 0 to 5 perceived discomfort scale: (0) no stinging; (1) very slight stinging; (2) weak stinging, no pain; (3) moderate stinging, with or without pain; (4) tolerable pain and stinging; and (5) severe pain and unbearable stinging.

[0101] Drops (45 μL) of the formulation were placed in the eyes of 20 subjects. For each subject, control drops were placed in one eye (left or right eye) and test drops were placed in the other eye.

[0102] For Phase I HEI testing, the control and test formulations were diluted into four different solutions ranging from 1% to 7.5% (1%, 3%, 5% and 7.5%, n=5 for all groups). Next, for Phase II HEI testing, the control and test formulations were diluted into 7.5% solutions and drops (45 μL) were applied to the subjects and the results were graded by an ophthalmologist.

[0103] In the HEI test, Composition A was associated with more perceived discomfort, conjunctival irritation, scleral redness, and tearing than Comparative # 1. However, as shown in Table 3 below, the results were not significant.

[0104] Table 3 - HEI test results for Composition A (SLES formulation)

[0105] Types of Assessment Composition A Comparison #1 p-value Discomfort / stinging 1.55 1.40 0.694 Conjunctival irritation 0.38 0.30 0.813 Redness of the sclera 0.38 0.28 0.688 Tears 0.03 0.00 1.000 Visual acuity No change No change --

[0106] The sulfate-free formulations of Compositions B to D as disclosed above containing a surfactant system containing cocamidopropyl betaine, coco-glucoside, disodium 2-sulfolaurate, and sodium methyl oleyl taurate or sodium cocoamphodiacetate were further subjected to HEI testing. The results are shown in Tables 4 to 6 below.

[0107] Table 4 - HEI test results for Composition B

[0108] Types of Assessment Composition B Comparison #1 p-value Discomfort / stinging 0.60 1.40 0.012 Conjunctival irritation 0.10 0.45 0.023 Redness of the sclera 0.10 0.45 0.023 Tears 0.00 0.00 1.000 Visual acuity No change No change --

[0109] Table 5 - HEI test results for Composition C

[0110] Types of Assessment Composition C Comparison #1 p-value Discomfort / stinging 0.65 1.30 0.014 Conjunctival irritation 0.15 0.45 0.041 Redness of the sclera 0.15 0.45 0.041 Tears 0.00 0.00 1.000 Visual acuity No change No change --

[0111] Table 6 - HEI test results for Composition D

[0112] Types of Assessment Composition D Comparison #1 p-value Discomfort / stinging 0.80 1.40 0.034 Conjunctival irritation 0.30 0.53 0.063 Redness of the sclera 0.30 0.58 0.063 Tears 0.00 0.03 1.000 Visual acuity No change No change --

[0113] As shown above, all four test compositions A to D passed the HEI test. Overall, the three sulfate-free formulations performed better than the SLES formulation. While not wishing to be bound by theory, it is believed that this may be due to a milder surfactant system, higher pH, and more tear film protectants. While not wishing to be bound by theory, the superior performance of compositions B and C relative to composition D may be due to the higher level of disodium cocoamphodiacetate in composition D.

[0114] The present disclosure has been described with reference to exemplary embodiments. Although a limited number of embodiments have been shown and described, it will be appreciated by those skilled in the art that changes may be made in these embodiments without departing from the principles and spirit of the foregoing detailed description. The present disclosure is intended to be interpreted as including all such modifications and variations as long as they fall within the scope of the appended claims or their equivalents.

Claims

1. A personal care composition comprising: (a) a surfactant system comprising at least one anionic surfactant and at least one amphoteric surfactant; and (b) at least one tear film protective agent, wherein the personal care composition has a pH ranging from about 4.0 to about 6.

0.

2. The personal care composition of claim 1, wherein the personal care composition has a Natural Origin Index based on ISO Standard 16128 of about 90% or greater.

3. The personal care composition according to claim 2, wherein said natural origin of said personal care composition based on ISO standard 16128 is about 96% or greater, preferably about 97% or greater.

4. A personal care composition according to any preceding claim, wherein the at least one anionic surfactant is selected from sulfate anionic surfactants.

5. The personal care composition of claim 4, wherein the sulfate anionic surfactant is sodium laureth sulfate (SLES).

6. A personal care composition according to any one of claims 1 to 3, wherein the at least one anionic surfactant is selected from sulfolaurate surfactants.

7. The personal care composition of claim 6, wherein the sulfolaurate surfactant is disodium 2-sulfolaurate.

8. A personal care composition according to any one of the preceding claims, wherein the at least one amphoteric surfactant is selected from betaine surfactants.

9. The personal care composition of claim 8, wherein the betaine surfactant is cocamidopropyl betaine.

10. A personal care composition according to any one of the preceding claims, wherein the surfactant system further comprises at least one nonionic surfactant.

11. A personal care composition according to claim 10, wherein the at least one nonionic surfactant is selected from glucoside surfactants, preferably coco-glucoside.

12. The personal care composition according to any one of the preceding claims, wherein the at least one tear film protectant is selected from glycerol and glyceryl oleate.

13. A personal care composition according to any one of the preceding claims, wherein the surfactant system further comprises a taurate surfactant, preferably sodium methyl oleoyl taurate.

14. A personal care composition according to any one of the preceding claims, wherein the pH ranges from about 4.2 to about 6.8, such as about 4.2 or about 5.

2.

15. The personal care composition of any preceding claim, further comprising at least one preservative selected from sodium benzoate and potassium sorbate.

16. A personal care composition according to claims 1 to 3 or claims 6 to 15, wherein the personal care composition is free of sulfate anionic surfactants.

17. A personal care composition according to any one of the preceding claims, further comprising at least one anti-allergic agent, such as dipropylene glycol (DPG) or bisabolol.

18. The personal care composition of any one of the preceding claims, wherein the at least one tear protectant is present in an amount of about 4 wt% to about 8 wt%, based on the total weight of the personal care composition.

19. The personal care composition according to any one of the preceding claims, wherein the personal care composition is free of thickeners.

20. The personal care composition according to any of the preceding claims, wherein the at least one anionic surfactant is present in an amount of about 3 wt. % to about 10 wt. %, based on the total weight of the personal care composition.

21. The personal care composition of any of the preceding claims, wherein the at least one amphoteric surfactant is present in an amount of about 5 wt. % to about 20 wt. %, based on the total weight of the personal care composition.

22. A personal care composition comprising: (a) a surfactant system comprising disodium 2-sulfolaurate, a glucoside surfactant and a betaine surfactant; and (b) at least two tear film protective agents, including glycerol and oleylglycerol, wherein the personal care composition is free of sulfate anionic surfactants and has a pH ranging from about 4.0 to about 6.

0.

23. A personal care composition comprising: (a) a surfactant system comprising a sulfate anionic surfactant and a betaine surfactant; and (b) at least two tear film protectants including glycerin and glyceryl oleate, wherein the personal care composition has a pH ranging from about 4.0 to about 6.0.

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