Electrode array and tumor electric field treatment system
By designing an electrode array, using the structure of the backbone and branch and the circuit connection method of row and column groups, the problem of excessive conductive traces in the prior art is solved, and the flexibility of the electrode sheet and effective temperature detection and treatment electric field application capabilities are achieved.
Patent Information
- Application Number
- CN202510281437.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2023-12-27
- Filing Date
- 2024-10-25
- Publication Date
- 2025-05-27
AI Technical Summary
In the existing tumor electric field treatment system, too many conductive traces of the electrode sheets make the electrode sheets not easy to bend, and the overall weight increases, affecting the application effect.
An electrode array is designed to form a backbone and branch through a plurality of electrode units and connection parts. The electrode units are divided into row groups and column groups on the circuit connection, and partition control is used to reduce the number of wires and maintain the flexibility of the electrode sheet.
Partition control of multiple electrode units is realized, the number of conductive traces is reduced, and the problems of increasing the weight of the electrode sheet and reducing the application effect are avoided, while maintaining the flexibility of the electrode sheet and effective temperature detection and treatment electric field application capabilities.
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Figure CN120037576A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to Tumor Treating Fields (TTF) technology, and in particular to an electrode array and a tumor treating field system. Background Art
[0002] Tumor electric field therapy is a method that uses low-intensity, medium- and high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, thereby inhibiting the separation of intracellular organelles during cell division and inducing cell apoptosis during mitosis, thereby achieving the purpose of treating tumors.
[0003] Compared with traditional cancer treatments, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them susceptible to TTF. TTF disrupts the normal aggregation of tubulin by exerting directional forces on polar particles (such as macromolecules and organelles) within the cell. These processes may lead to physical damage to the cell membrane and cell apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow will lead to an uneven distribution of the electric field around it. At the same time, under the influence of TTF, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move toward the cleavage furrow, which interferes with or even destroys the formation of the cell structure, and ultimately leads to cell division failure and apoptosis.
[0004] In the existing tumor electric field therapy system, an electric field generator is used to transmit the alternating current signal for tumor electric field therapy to the electrode sheet, and then the alternating electric field is applied to the patient's tumor site through the electrode sheet for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat will accumulate at the electrode sheet application site, and the temperature of the electrode sheet application site will also increase accordingly. Therefore, it is necessary to monitor the temperature of the electrode sheet application site at all times. When the monitored temperature rises to a certain preset value, it is necessary to adjust the electric field strength applied to the patient's tumor site in a timely manner to avoid excessive temperature at the electrode sheet application site, which may cause burns to the patient's skin.
[0005] The tumor electric field therapy system includes at least one pair of electrode sheets, each of which has multiple electrode units. Even if the same alternating current signal is applied to each electrode unit, the heat generated by each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the entire electrode sheet will not be completely consistent. In this way, it is possible that the temperature of some electrode units in the entire electrode sheet exceeds the preset temperature, while the temperature of other electrode units is normal. In order to ensure that the tumor electric field therapy has a sufficiently long application time while avoiding low-temperature burns on the patient's body surface, it is necessary to implement separate control on the over-temperature electrode unit. However, for existing electrode sheets, implementing separate control on the electrode units requires that a conductive trace be set for each electrode unit in the substrate of the electrode sheet, which will increase the number of conductive traces in the electrode sheet substrate so that the electrode sheet is not easy to bend, and the cable electrically connected to the electrode sheet will also be thickened, which increases the overall weight of the electrode sheet, which is not conducive to the application of the electrode sheet.
[0006] Therefore, it is necessary to provide an electrode sheet temperature detection method for performing partition control on multiple electrode units using fewer conductive traces. Summary of the invention
[0007] The purpose of the present application is to provide an electrode array and a tumor electric field treatment system to solve or eliminate the problems in the related art.
[0008] To achieve the above-mentioned purpose, the present application provides the following technical solutions: an electrode array for applying an alternating current signal to an electrode, comprising a plurality of electrode units and a plurality of connecting parts connecting two adjacent electrode units, wherein some of the connecting parts respectively connect two adjacent electrode units and together with the corresponding electrode units form at least one trunk of the electrode array, and the remaining connecting parts respectively connect two adjacent electrode units and together with the corresponding electrode units form a plurality of branches extending laterally from the trunk, and the relative positions between the electrode units at the ends of two adjacent branches can be freely adjusted, and the plurality of electrode units are divided into at least two row groups and at least two column groups in terms of circuit connection, and the grounding ends of the electrode units in each row group are grounded through their corresponding grounding wires, and the signal input ends of the electrode units in each row group are short-circuited in parallel to their corresponding dual-purpose signal lines, and the dual-purpose signal lines transmit direct current signals to the electrode units in the corresponding column groups in linkage with the grounding wires to collect temperature detection signals of the electrode units or transmit alternating current signals for tumor treatment.
[0009] Furthermore, each of the branches is connected to a corresponding electrode unit located on the trunk through a connecting portion, and the electrode units located on adjacent branches are arranged in a disconnected state.
[0010] Furthermore, the branch at least includes a connecting portion and an electrode unit electrically connected to the connecting portion.
[0011] Furthermore, the signal input ends of the electrode units in the same row group are connected in parallel through different dual-purpose signal lines, the signal input ends of the electrode units in different column groups are connected in parallel through different dual-purpose signal lines, and the ground ends of the electrode units in the same column group are connected in parallel through different ground lines.
[0012] Furthermore, the plurality of electrode units are distributed at intervals in the spatial structure to form a plurality of intervals.
[0013] Furthermore, the interval is located between adjacent branches, and the position between adjacent branches is adjustable.
[0014] Furthermore, the transmission time of the direct current signal and the transmission time of the alternating current signal by the dual-purpose signal line do not overlap each other.
[0015] Furthermore, the electrode unit includes a dielectric element for transmitting an AC signal and a temperature sensor for transmitting a DC signal. The ground terminal of the electrode unit is the ground terminal of the temperature sensor. The signal terminal of the temperature sensor is short-circuited with the dielectric element and serves as the signal input terminal of the electrode unit after short-circuiting.
[0016] Furthermore, the ground wire and the dual-purpose signal wire are both embedded in the connecting portion.
[0017] The present application also provides a tumor electric field treatment system, which includes the above-mentioned electrode array.
[0018] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 A schematic diagram of a framework of a tumor electric field treatment system according to an embodiment of the present application, wherein a schematic diagram of the structure of the electrode sheet according to the first embodiment is shown; Figure 2 For use in this application Figure 1 A schematic structural diagram of a modified embodiment of the electrode sheet of the first embodiment of the tumor electric field treatment system shown; Figure 3 For this application Figure 1 The circuit connection diagram of the tumor electric field system shown in FIG. Figure 1 The electrode sheet of the first embodiment shown or Figure 2 The electrode sheet of the modified embodiment shown in Figure 1 A circuit connection diagram of the adapter of the first embodiment shown in FIG. Figure 4 For this application Figure 3 A schematic block diagram of the internal structure of the adapter shown; Figure 5 For this application Figure 1 A schematic block diagram of the internal structure of an electric field generator of a tumor electric field treatment system is shown; Figure 6 and Figure 3 Similarly, FIG. 1 is a circuit connection diagram of the tumor electric field treatment system according to the second embodiment of the present application, which shows the electrode sheet and the second embodiment of the tumor electric field treatment system according to the present application. Figure 3 The circuit connection diagram of the adapter shown; Figure 7 and Figure 3 Similarly, FIG. 1 is a circuit connection diagram of the tumor electric field treatment system according to the third embodiment of the present application, which shows the electrode sheet and the third embodiment of the tumor electric field treatment system according to the present application. Figure 3 The circuit connection diagram of the adapter shown; Figure 8 and Figure 3 Similarly, FIG. 1 is a circuit connection diagram of the tumor electric field treatment system according to the fourth embodiment of the present application, which shows the electrode sheet and the fourth embodiment of the tumor electric field treatment system according to the present application. Figure 3 The circuit connection diagram of the adapter shown; Fig. 9 and Figure 1 Similarly, this is a schematic diagram of the framework of the tumor electric field treatment system according to the fifth embodiment of the present application, which shows a schematic diagram of the structure of the electrode sheet according to the fifth embodiment; Fig.10 (A) Fig. 9 A structural schematic diagram of a modified embodiment of the electrode sheet of the fifth embodiment of the tumor electric field treatment system of the present application is shown in FIG. Fig.10 (B) with Fig.10 (A) Similar to Fig. 9 A structural schematic diagram of another alternative embodiment of the electrode sheet of the fifth embodiment of the tumor electric field treatment system of the present application is shown in FIG. Fig.11 and Figure 3 Similar to Fig. 9 A circuit connection diagram of the tumor electric field treatment system shown in FIG. Fig. 9 The electrode sheet of the fifth embodiment shown or Fig.10 (A) Fig.10 The electrode sheet of the modified embodiment shown in (B) is Figure 3 The circuit connection diagram of the adapter shown; Fig.12 and Fig.11 Similarly, the circuit connection diagram of the tumor electric field treatment system of the sixth embodiment of the present application is shown. Fig. 9 The electrode sheet of the fifth embodiment shown or Fig.10 (A) Fig.10 The electrode sheet of the modified embodiment shown in (B) is Figure 3 Another circuit connection diagram of the adapter shown; Fig.13 and Fig.12 Similarly, the circuit connection diagram of the tumor electric field treatment system of the seventh embodiment of the present application is shown. Fig. 9 The electrode sheet of the fifth embodiment shown or Fig.10 (A) Fig.10 The electrode sheet of the modified embodiment shown in (B) is Figure 3 Another circuit connection diagram of the adapter shown; Fig.14 and Fig.12 Similarly, the circuit connection diagram of the tumor electric field treatment system of the eighth embodiment of the present application is shown. Fig. 9 The electrode sheet of the fifth embodiment shown or Fig.10 (A) Fig.10 The electrode sheet of the modified embodiment shown in (B) is Figure 3 Another circuit connection diagram of the adapter shown; Fig.15 and Figure 1 Similarly, the schematic diagram of the framework of the tumor electric field treatment system of the ninth embodiment of the present application is shown, wherein the schematic diagram of the structure of the electrode sheet of the ninth embodiment is shown; Fig.16 for Fig.15 The circuit connection diagram of the tumor electric field treatment system shown in FIG. Fig.15 The electrode sheet of the ninth embodiment shown in FIG. Figure 3 The circuit connection diagram of the adapter shown; Fig.17 and Fig.16 Similarly, the circuit connection diagram of the tumor electric field treatment system of the tenth embodiment of the present application is shown. Fig.15 The electrode sheet of the ninth embodiment shown in FIG. Figure 3 Another circuit connection diagram of the adapter shown; Fig.18 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field treatment system of the eleventh embodiment of the present application is shown. Figure 1The electrode sheet of the first embodiment shown or Figure 2 A schematic diagram of a circuit connection between the electrode sheet of the variation embodiment shown in and the adapter of the second embodiment; Fig.19 and Figure 6 Similarly, the circuit connection diagram of the tumor electric field treatment system of the twelfth embodiment of the present application is shown. Figure 6 A schematic diagram of circuit connection between another alternative embodiment of the electrode sheet shown and the adapter of the second embodiment; Fig. 20 for Fig.18 and Fig.19 Schematic block diagram of the internal structure of the adapter used in the second embodiment of the tumor electric field treatment system of the present application; Fig.21 This is a circuit connection diagram of the tumor electric field treatment system of the thirteenth embodiment of the present application, which shows a circuit connection diagram of the electrode sheet of the thirteenth embodiment of the tumor electric field treatment system of the present application and the adapter of the third embodiment; Fig. 22 This is a circuit connection diagram of the tumor electric field treatment system of the fourteenth embodiment of the present application, which shows Figure 7 A schematic diagram of circuit connection between a modified embodiment of the electrode sheet and the adapter of the third embodiment; Fig.23 for Fig.21 and Fig. 22 Schematic block diagram of the internal structure of the adapter used in the third embodiment of the tumor electric field treatment system of the present application; Fig.24 FIG. 1 is a circuit connection diagram of a tumor electric field treatment system according to another embodiment of the present application, which shows Fig.11 A schematic diagram of the circuit connection between the electrode sheet shown and the adapter of the fourth embodiment; Fig.25 Another circuit connection diagram of the tumor electric field treatment system of the present application shows Fig.12 A schematic diagram of the circuit connection between the electrode sheet shown and the adapter of the fourth embodiment; Fig.26 for Fig.24 and Fig.25 Schematic block diagram of the internal structure of the adapter used in the fourth embodiment of the tumor electric field treatment system of the present application; Fig. 27 A circuit connection diagram of a tumor electric field treatment system according to another embodiment of the present application shows Fig.13 A schematic diagram of the circuit connection between the electrode sheet shown and the adapter of the fifth embodiment; Fig.28 FIG. 1 is a circuit connection diagram of a tumor electric field treatment system according to another embodiment of the present application, which shows Fig.14 A schematic diagram of the circuit connection between the electrode sheet shown and the adapter of the fifth embodiment; Fig.29 For this application Fig. 27 and Fig.28 Schematic block diagram of the internal structure of the adapter used in the fifth embodiment of the tumor electric field treatment system of the present application; Fig.30 FIG. 1 is a circuit connection diagram of a tumor electric field treatment system according to another embodiment of the present application, which shows Fig.16 A schematic diagram of the circuit connection between the electrode sheet shown and the adapter of the sixth embodiment; Fig.31 for Fig.30 A schematic block diagram of the internal structure of the adapter used in the sixth embodiment of the tumor electric field treatment system of the present application is shown in FIG. Fig.32 FIG. 1 is a circuit connection diagram of a tumor electric field treatment system according to another embodiment of the present application, which shows Fig.17 A schematic diagram of the circuit connection between the electrode sheet shown and the adapter of the seventh embodiment; Fig.33 for Fig.32 Schematic block diagram of the internal structure of the adapter used in the seventh embodiment of the tumor electric field treatment system of the present application; Fig.34 A schematic flow chart of a temperature detection method of a tumor electric field therapy system according to an embodiment of the present application; Fig.35 A schematic flow chart of a method for controlling application of an alternating current signal for electric field therapy of tumors according to an embodiment of the present application; Fig.36 A schematic flow chart of a signal control method for tumor electric field therapy according to an embodiment of the present application; Fig.37 A schematic flow chart of an electrode sheet temperature detection method according to another embodiment of the present application; Fig.38 A schematic flow chart of a method for applying an alternating current signal for electric field therapy of tumors according to another embodiment of the present application; Fig.39 A schematic flow chart of a method for applying an alternating current signal based on a temperature detection signal according to an embodiment of the present application; Fig.40 It is a flowchart of a method for applying an alternating current signal based on a temperature detection signal according to another embodiment of the present application.
[0020] Description of reference numerals: Tumor electric field treatment system 100, 100D, 100G, electrode sheets 10, 10', 10A, 10B, 10C, 10D, 10D', 10D", 10E, 10F, 10G, 10H, 10J, 10K, 10L, 10M, 10N, flexible circuit board 11, 11A, 11B, 11C, 11D, 11E, 11F, 11G, 11H, 11J, 11K, 11L, 11M, 11N, connecting portion 111, 111', connecting portion 112, 112', bridging portion 113, 113', trunk 114, branch 115, electrode unit 12, 12-1, 12-2, 12-3, 12-4, 12-5, 12-6, 12-7, 12-8, 12-9, 12-10, 12-11, 12-12, 12-13, 12-14, 12-15, 12-16, 12-17, 12-18, 12-19, 12-20, first cable 13, 13', 13D, 13D', 13D", 13H, temperature sensor 14, ground terminal 14-1, signal terminal 14-2, dielectric element 15, diode 16, ground wire 18, first ground wire 18-1, second ground wire 18-2, third ground wire 18-3, fourth ground wire 18-4, fifth ground wire 18-5, dual-purpose signal wire 19, first dual-purpose signal wire 19-1, second dual-purpose signal wire 19-2, third dual-purpose signal wire 19-3, fourth dual-purpose signal wire 19-4, The fifth dual-purpose signal line 19-5, the sixth dual-purpose signal line 19-6, the adapter 20, 20K, 20M, 20B, 20C, 20D, 20E, the second cable 21, the first controller 22, the analog-to-digital converter 23, the voltage divider resistor 24, the grounding switch 25, the first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, the fourth grounding switch 25-4, the fifth grounding switch 25-5, the bidirectional switch 26, the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, the fifth bidirectional switch 26-5, the sixth bidirectional switch 26-6, the first communication unit 27, the AC signal line 28, the a power module 29, an electric field generator 30, a second power module 31, a second controller 32, a second communication unit 33, an AC signal generator 34, an AC signal switch 35, a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, a fourth AC signal switch 35-4, an AC signal connection 36, a first AC signal connection 36-1, a second AC signal connection 36-2, a third AC signal connection 36-3, a fourth AC signal connection 36-4, a first connector 40, 40A, 40B, 40C, 40D, 40E, 40F, 40G, 40H, 40J, 40K, 40L, 40M, 40D', 40E', 40F', 40G',40H', a first plug 41, 41', 41D, 41D', 41D", 41H, a first socket 42, a second connector 50, a second plug 51, and a second socket 52. DETAILED DESCRIPTION
[0021] The following embodiments of the technical solution of the present application are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application, and are therefore only used as examples, and cannot be used to limit the scope of protection of the present application.
[0022] Figure 1 FIG. 1 is a schematic diagram of a tumor electric field treatment system 100 according to an embodiment of the present application. Figure 1 As shown, the tumor electric field treatment system 100 includes: at least one pair of electrode sheets 10, an adapter 20 electrically connected to the electrode sheets 10, and an electric field generator 30 electrically connected to the adapter 20. The electric field generator 30 generates an alternating current signal for tumor treatment and applies the alternating current signal to the electrode sheets 10 through the adapter 20 to generate a therapeutic electric field between the electrode sheets 10 arranged in pairs. The adapter 20 is electrically connected between the electrode sheets 10 and the electric field generator 30, and is used to transmit the alternating current signal generated by the electric field generator 30 to the electrode sheets 10. In other words, the electric field generator 30 is capable of generating an alternating current signal, and the generated alternating current signal is transmitted to each electrode sheet 10 through the adapter 20, so that a therapeutic electric field for treating tumors is generated between the same pair of electrode sheets 10.
[0023] like Figure 1 As shown, in this embodiment, the number of electrode sheets 10 is 4. From the perspective of spatial structural arrangement, each electrode sheet 10 includes a plurality of electrode units 12 that are both axially symmetrically arranged and centrally symmetrically arranged and of the same number, a plurality of connecting portions 111 located between two adjacent electrode units 12, a bridging portion 113 erected between two adjacent connecting portions 111, a wiring portion 112 connected to the bridging portion 113, and a first cable 13 connected to the wiring portion 112. The bridging portion 113 and the wiring portion 112 are arranged vertically to form a "T" shape. The bridging portion 113 is erected between two adjacent connecting portions 111. Each electrode unit 12 of the electrode sheet 10 is electrically connected to the adapter 20 via the first cable 13.
[0024] Each electrode unit 12 has a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature of the patient's body surface where the electrode unit 12 is applied. It can be a thermistor element or other temperature sensors other than thermistors, and can be set at any position on the electrode unit 12. The dielectric element 15 is used to apply an alternating current signal to the patient's tumor site. The dielectric element 15 can be a dielectric ceramic sheet or a polymer dielectric layer composed of a polymer material. In this embodiment, each dielectric element 15 has a through-hole (unnumbered) arranged in the middle to accommodate a corresponding temperature sensor 14. Each electrode unit 12 can also include a diode 16 connected in series with the temperature sensor 14, which can prevent the reverse flow of current to prevent the detection signal from other electrode units 12 from affecting the temperature sensor 14. The ground terminal 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16 and is grounded through the cathode of the diode 16.
[0025] In the first mode, the electrode unit 12 applies an alternating current signal through the dielectric element 15; in the second mode, the temperature sensor 14 is used to detect or collect the temperature of the patient's body surface to which the corresponding electrode unit 12 is attached; in the third mode, the application of the alternating current signal is stopped and the temperature detection and collection are stopped. The first mode, the second mode, and the third mode do not overlap each other in time periods. That is, the time period in which the dielectric element 15 of the electrode unit 12 applies the alternating current signal is staggered and does not overlap with the time period in which the temperature sensor 14 detects the temperature. The electrode unit 12 can switch cyclically between applying an alternating current signal through its dielectric element 15 and detecting the temperature through its temperature sensor 14, that is, the electrode unit 12 can switch cyclically between the first mode and the second mode. The electrode unit 12 can also switch cyclically between the first mode, the second mode, and the third mode, that is, the electrode unit 12 switches cyclically between applying an alternating current signal through the dielectric element 15, collecting or detecting the temperature through the temperature sensor 14, and stopping applying the alternating current signal and collecting the temperature.
[0026] Each electrode sheet 10 includes an electrode array (not numbered) consisting of 20 electrode units 12. The electrode array (not numbered) also has a flexible circuit board 11 including a connecting portion 111, a wiring portion 112, and a bridging portion 113. The 20 electrode units 12 are distributed in an electrode array (not numbered) arranged in four rows and six columns in an interval shape. Specifically, four electrode units 12 are arranged in each of the first and last rows, and six electrode units 12 are arranged in each of the two middle rows. The four electrode units 12 in the first row are respectively located in each of the second to fifth columns, the six electrode units 12 in each of the two middle rows are respectively located in each of the first to sixth columns, and the four electrode units 12 in the last row are also respectively located in each of the second to fifth columns.
[0027] The connection portion 111 is only located between two adjacent electrode units 12 arranged in the column direction in each of the third and fourth columns, and between the remaining two adjacent electrode units 12 in the row direction except the two electrode units 12 in the third and fourth columns in each row. That is, the two adjacent electrode units 12 in the third and fourth columns are only connected in the column direction through the connection portion 111, and are disconnected in the row direction and not connected by the connection portion 111; the electrode units 12 in the first, second, fifth and sixth columns are only connected to the electrode units 12 adjacent to them in the row direction through the connection portion 111 arranged in the horizontal direction, and the electrode units 12 adjacent to them in the column direction are disconnected. That is to say, the two adjacent electrode units 12 in the first, second, fifth and sixth columns are disconnected.
[0028] The electrode units 12 located in the third column and the connecting portions 111 located between the electrode units 12 in the column and arranged longitudinally, and the electrode units 12 located in the fourth column and the connecting portions 111 located between the electrode units 12 in the column and also arranged longitudinally all constitute the trunk 114 of the electrode array (not numbered). The connecting portions 111 located on the opposite sides of the electrode units 12 in the third column and the fourth column and connected to the electrode units 12 in the third column and the fourth column respectively through the connecting portions 111 arranged transversely and the electrode units 12 connected to the connecting portions 111 arranged transversely all constitute the branches 115 of the electrode array (not numbered). That is, in this embodiment, the electrode array (not numbered) includes two trunks 114 and a plurality of branches 115 extending laterally from the two trunks 114. Each branch 115 has a free end away from the trunk 114, and the free ends of adjacent branches 115 are arranged in a disconnected state, and the position and distance between adjacent branches 115 can be freely adjusted according to the actual use scenario. Specifically, one trunk 114 is composed of the electrode units 12 located in the third column and the connecting portions 111 located between the adjacent electrode units 12 in the column and arranged in a longitudinal direction, and another trunk 114 is composed of the electrode units 12 located in the fourth column and the connecting portions 111 located between the adjacent electrode units 12 in the column and arranged in a longitudinal direction. The remaining electrode units 12 connected to the trunk 114 through the connecting portions 111 arranged in a transverse direction and the connecting portions 111 arranged in a transverse direction are all branches 115.
[0029] Specifically, the branches 115 are: a connecting portion 111 extending laterally to the left from the electrode unit 12 in the first row of the third column and located in the first row, and an electrode unit 12 connected to the connecting portion 111 and located in the second column of the first row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the second row of the third column and located in the second row, and two electrode units 12 located in the first column of the second row and the second column of the second row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the third row of the third column and located in the third row, and two electrode units 12 located in the first column of the third row and the second column of the third row; a connecting portion 111 extending laterally to the left from the electrode unit 12 in the fourth row of the third column and located in the fourth row, and The electrode unit 12 in the second column of the fourth row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the first row of the fourth column and located in the first row, and an electrode unit 12 located in the fifth column of the first row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the second row of the fourth column and located in the second row, and two electrode units 12 located in the fifth column of the second row and the sixth column of the second row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the third row of the fourth column and located in the third row, and two electrode units 12 located in the fifth column of the third row and the sixth column of the third row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the fourth row of the fourth column and located in the fourth row, and an electrode unit 12 located in the fifth column of the fourth row.
[0030] The electrode array (unnumbered) is divided into a symmetrical left part including three columns on the left and a right part including three columns on the right, and the left part and the right part are connected only by a bridge portion 113. The left part is composed of a trunk 114 located in the third column and a plurality of branches 115 extending laterally to the left from the trunk 114, and the right part is composed of a trunk 114 located in the fourth column and a plurality of branches 115 extending laterally to the right from the trunk 114. The two trunks 114 are connected by a bridge portion 113 arranged therebetween. Specifically, the two trunks 114 are electrically connected by a bridge portion 113 arranged between a connection portion 111 connecting an electrode unit 12 in the second row of the third column and an electrode unit 12 in the third row of the third column and a connection portion 111 connecting an electrode unit 12 in the second row of the fourth column and an electrode unit 12 in the third row of the fourth column. The connecting portion 111 connecting the electrode unit 12 in the second row of the third column and the electrode unit 12 in the third row of the third column, the connecting portion 111 connecting the electrode unit 12 in the second row of the fourth column and the electrode unit 12 in the third row of the fourth column, and the bridging portion 113 are generally arranged in an "H" shape. In other embodiments, the bridging portion 113 may also be arranged between an electrode unit 12 located in the third column and an electrode unit 12 located in the fourth column. Optionally, the bridging portion 113 is arranged between two electrode units 12 located in the third column and the fourth column and adjacent in the row direction.
[0031] Each electrode unit 12 can be divided into an electrode unit 12 located at the periphery and an electrode unit 12 located at the center according to its position in the electrode array (unnumbered). The electrode units 12 located at the periphery include four electrode units 12 located in the first row, two electrode units 12 located at opposite ends of the second row, two electrode units 12 located at opposite ends of the third row, and four electrode units 12 located in the fourth row. The electrode units 12 located at the center include four electrode units 12 located in the middle of the second row and four electrode units 12 located in the middle of the third row. Some adjacent two electrode units 12 in the plurality of electrode units 12 located at the periphery are connected by a laterally arranged connecting portion 111, and some adjacent two electrode units 12 are arranged in a disconnected state. Two adjacent electrode units 12 in the plurality of electrode units 12 located at the periphery that are connected by a connecting portion 111 are two electrode units 12 that are adjacent in some rows. Specifically, among the plurality of electrode units 12 located at the periphery, two electrode units 12 adjacent in the column direction and adjacent in the diagonal direction are all arranged in a disconnected state; some two electrode units 12 adjacent in the row direction are also arranged in a disconnected state; only some two electrode units 12 adjacent in the row direction are connected by a laterally extending connection portion 111. Among the plurality of electrode units 12 located at the center, only two electrode units 12 adjacent in the column direction located on the trunk 114 are connected by a longitudinally arranged connection portion 111, and only two electrode units 12 adjacent in the row direction located on the branch 115 are connected by a laterally arranged connection portion 111.
[0032] The electrode array (unnumbered) also has intervals (unnumbered) formed between a number of electrode units 12 distributed at intervals, which can allow moisture on the patient's body surface to escape, heat exchange between the patient's skin and the outside world, or allow the patient's skin to breathe freely, and also allow the positions and spacings between the branches 115 to be freely adjusted, and can also prevent the electrode sheet 10 from wrinkling when applied. The intervals (unnumbered) include a first interval D1 located between the two trunks 114 and a second interval D2 located between the branches 115. The first interval D1 is located between the third column of electrode units 12 and the fourth column of electrode units 12, and the second interval D2 is located between the electrode units 12 in adjacent rows. That is, along the row upward, the electrode unit 12 located in the third column is disconnected from the adjacent electrode unit 12 located in the fourth column, and no connecting portion 111 is provided, but the aforementioned first interval D1 is formed; and along the column upward, only the two adjacent electrode units 12 in the third column and the fourth column are connected by the connecting portion 111, and the two adjacent electrode units 12 in the column direction in each of the other four columns are not connected by the connecting portion 111 but form the aforementioned second interval D2. The setting of the first and second intervals D1 and D2 can also increase the degree of freedom of some electrode units 12, and can also avoid wrinkles when attaching the electrode sheet 10.
[0033] In some other embodiments, the tumor electric field therapy system 100 may also have more or fewer electrode sheets 10. In some other embodiments, each pair of electrode sheets 10 has the same number of electrode units 12, and different pairs of electrode sheets 10 may also have different numbers of electrode units 12. In some other embodiments, the 20 electrode units 12 may also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 10 may also have other numbers of electrode units 12. In short, the implementation of the present application is not limited by the number and arrangement of the electrode units 12 of the electrode sheet 10.
[0034] Figure 2 The electrode sheet 10' shown is Figure 1 A variation of the electrode sheet 10 shown in the figure has the same spatial structure as the electrode sheet 10, and also includes a plurality of electrode units 12' arranged at intervals, a plurality of connecting portions 111' located between two adjacent electrode units 12', a wiring portion 112' connected to the bridging portion 113', a first cable 13' connected to the wiring portion 112', a first interval D1 formed between the third column electrode unit 12' and the fourth column electrode unit 12', and a second interval D2' formed between adjacent rows of electrode units 12'; The only difference is that: the two electrode units 12' adjacent to each other in the column direction in the fourth column are both disconnected and not connected by the longitudinally arranged connecting portion 111', but the two electrode units 12' adjacent to each other in the column direction in the fifth column are connected by the longitudinally arranged connecting portion 111', and each electrode unit 12' in the fourth column is connected to the electrode unit 12' adjacent to each other in the row direction in the fifth column through the transversely arranged connecting portion 111'; and the bridging portion 113' is connected between the two electrode units 12' located in the third row and the third column and the third row and the fourth column.
[0035] Figure 3 for Figure 1 The diagram shows a circuit connection diagram of the first embodiment of the electrode sheet 10 or its variant embodiment of the electrode sheet 10 ' and the adapter 20 of the first embodiment. It is worth noting that: Figure 3 The arrangement of the electrode units 12 shown is to more clearly illustrate the electrical connection between an electrode sheet 10 and an adapter 20. Figure 3 The arrangement of the electrode units 12 shown does not represent the arrangement of the electrode units 12 in the spatial structure. The following describes the circuit connection by taking the electrode sheet 10 in the first embodiment as an example. Figure 1 as well as Figure 3The flexible circuit board 11 is embedded with multiple conductive traces 18, 19, including multiple grounding wires 18 and multiple dual-purpose signal wires 19. The first cable 13 has a multi-core wire (not shown) that is electrically connected to the multiple grounding wires 18 and the multiple dual-purpose signal wires 19 of the flexible circuit board 11 in a one-to-one correspondence. The total number of grounding wires 18 and dual-purpose signal wires 19 embedded in the flexible circuit board 11 does not exceed 10. Therefore, the number of wires of the first cable 13 does not exceed 10.
[0036] In this embodiment, each electrode sheet 10 is provided with 20 electrode units 12, and the 20 electrode units 12 are arranged in the order of 1 to 20 in the circuit connection, and are divided into four row groups and five column groups, that is, the 20 electrode units 12 are arranged in four rows and five columns in the circuit connection. The temperature sensor 14 of each electrode unit 12 includes a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and the temperature sensor 14 of each electrode unit 12 are soldered on the flexible circuit board 11, and each dielectric element 15 is short-circuited with the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in four rows and five columns in the circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, the multiple temperature sensors 14 are also arranged in four rows and five columns in the circuit connection, and the multiple dielectric elements 15 are also arranged in four rows and five columns in the circuit connection. It should be noted that the arrangement here is to more clearly show the electrical connection between the electrode sheet 10 and the adapter 20, and does not represent the arrangement of the electrode unit 12 in the spatial structure. Figure 1 The structure shown is roughly in the form of an array, but may also be other structures, such as petal-shaped or scattered, and may be regular or irregular. The dielectric element 15 is configured to apply an alternating electric field to the patient's tumor site. The temperature sensor 14 is configured to detect the temperature of the patient's body surface attached to the electrode sheet 10 and output a temperature detection signal to the adapter 20. In this embodiment, the multiplexed signal lines 19 of the flexible circuit board 11 are respectively arranged in one-to-one correspondence with the multiple column groups of the electrode unit 12, and are configured to transmit the alternating current signal generated by the electric field generator 30 to the dielectric elements 15 in each electrode unit 12 in the corresponding column group. That is, the dielectric elements 15 in the same column group are short-circuited by the same dual-purpose signal line 19 of the flexible circuit board 11, and the dielectric elements 15 in different column groups are connected in parallel by different dual-purpose signal lines 19 of the flexible circuit board 11. The dual-purpose signal lines 19 of the flexible circuit board 11 are electrically connected to the corresponding wires in the first cable 13 one by one, and then electrically connected to the electric field generator 30 via the adapter 20. That is, the dual-purpose signal lines 19 of the flexible circuit board 11 receive the alternating current signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.
[0037] The multiple grounding wires 18 are respectively arranged in one-to-one correspondence with the multiple row groups of the electrode units 12, and the multiple grounding wires 18 are respectively used to short-circuit the temperature sensor 14 of each electrode unit 12 corresponding to each row group to the ground. That is, the grounding ends 14-1 of the multiple temperature sensors 14 in the same row group are short-circuited through the same grounding wire 18 of the flexible circuit board 11, and the grounding ends 14-1 of the temperature sensors 14 in different row groups are respectively connected to the ground in parallel through different grounding wires 18 of the flexible circuit board 11. During the time period of temperature detection or in the second mode, only one of the multiple grounding wires 18 is turned on at the same time, and the rest are turned off.
[0038] Each of the multiplexed dual-purpose signal lines 19 is also configured to transmit a direct current signal to the temperature sensor 14 in each electrode unit 12 in the corresponding column group to collect and transmit the temperature signal obtained by the detection. The signal ends 14-2 of the multiple temperature sensors 14 located in different column groups are respectively connected in parallel through different dual-purpose signal lines 19 of the flexible circuit board 11, and the signal ends 14-2 of the multiple temperature sensors 14 located in the same column group are short-circuited to the same dual-purpose signal line 19 of the flexible circuit board 11. Specifically, each dual-purpose signal line 19 is configured to short-circuit the signal end 14-2 of the temperature sensor 14 of at most one electrode unit 12 in each row group to an external device for receiving the detection signal, wherein the signal ends 14-2 of the temperature sensors 14 connected to each of the multiplexed dual-purpose signal lines 19 are different from each other to avoid the dual-purpose signal line 19 from outputting duplicate signals later. That is, when the number of electrode units 12 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal end 14-2 of the temperature sensor 14 of a different electrode unit 12 in the row group; when the number of electrode units 12 in a row group is less than the number of dual-purpose signal lines 19, there is at least one dual-purpose signal line 19 that is not electrically connected to the signal end 14-2 of the temperature sensor 14 of the electrode unit 12, and each of the remaining dual-purpose signal lines 19 is electrically connected to the signal end 14-2 of the temperature sensor 14 of a different electrode unit 12 in the row group. In this embodiment, the external device for receiving the detection signal is an adapter 20. The dual-purpose signal line 19 of the flexible circuit board 11 receives the DC signal from the adapter 20 or the electric field generator 30 through the first cable 13, and transmits the collected or detected temperature signal to the adapter 20, and then transmits it to the electric field generator 30 through the adapter 20.
[0039] In this embodiment, when each electrode unit 12 is equipped with a temperature sensor 14 for temperature detection, the above-mentioned circuit design is used to reduce the number of wires of the first cable 13, so as to avoid the cable becoming thicker and the cable becoming harder, thereby increasing the difficulty of fixing the cable; at the same time, the increase in the number of wires of the first cable 13 is avoided to affect the adhesion effect between the electrode sheet 10 and the body surface corresponding to the tumor site of the patient. The grounding wire 18 and the dual-purpose signal wire 19 embedded in the flexible circuit board 11 are a total of 9 lines. Specifically, in this embodiment, the grounding wire 18 embedded in the flexible circuit board 11 is 4 lines, and the dual-purpose signal wire 19 is 5 lines. In other embodiments, the grounding wire 18 and the dual-purpose signal wire 19 embedded in the flexible circuit board 11 may also have other numbers according to the circuit arrangement and quantity differences of the electrode units 12 in different electrode sheets, which will be specifically explained in subsequent embodiments.
[0040] In the tumor electric field therapy system 100, the number of conductive lines electrically connected to the grounding line 18 is related to the number of row groups M of the electrode unit 12, which may be greater than or equal to the number of row groups of the electrode unit 12, and M is a positive integer. In the tumor electric field therapy system 100, the number of conductive lines electrically connected to the dual-purpose signal line 19 is related to the number of column groups N of the electrode unit 12, which may be greater than or equal to the number of column groups of the electrode unit 12, and N is a positive integer. The line L embedded in the flexible circuit board 11 of the electrode sheet 10 is equal to the sum of the number of grounding lines 18 and the number of dual-purpose signal lines 19. In the present embodiment, the number of grounding lines 18 is equal to the number of row groups M of the electrode unit 12; the dual-purpose signal line 19 is equal to the number of column groups N of the electrode unit 12.
[0041] exist Figure 3In the illustrated embodiment, the electrode sheet 10 includes four grounding wires 18, each of which is used to ground the grounding ends 14-1 of the temperature sensors 14 in the same row group. The four grounding wires 18 of the electrode sheet 10 are respectively a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. In the four row groups of the electrode sheet 10, the first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-20. Specifically, the first grounding wire 18-1 is used to ground the electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground the electrode units 12-6 to 12-10 in the second row group; the third grounding wire 18-3 is used to ground the electrode units 12-11 to 12-15 in the third row group; the fourth grounding wire 18-4 is used to ground the electrode units 12-16 to 12-20 in the fourth row group. It should be noted that these grounding wires 18 can be selectively closed or disconnected, which can be achieved by connecting each grounding wire 18 in series with a switch, which will be described in detail below. The above-mentioned "grounding the electrode unit 12" can refer to grounding the ground terminal 14-1 of the temperature sensor 14 in the electrode unit 12, or it can refer to the diode 16 being connected in series with the temperature sensor 14 of the same electrode unit 12 and grounded together. In short, each ground line 18 short-circuits the ground terminals 14 - 1 of the temperature sensors 14 of all the electrode units 12 in each row group and connects them to the ground.
[0042] Continue to refer Figure 3As shown, the electrode sheet 10 of this embodiment also includes 5 dual-purpose signal lines 19, one end of each dual-purpose signal line 19 is respectively connected to all electrode units 12 in each column group, and the other end thereof is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. That is, for each row group, each dual-purpose signal line 19 can choose to connect to one of the electrode units 12 or not connect to any electrode unit 12 in the row group to avoid the dual-purpose signal line 19 from subsequently outputting duplicate signals. Specifically, the 5 dual-purpose signal lines 19 of the electrode sheet 10 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-2, electrode unit 12-7, electrode unit 12-12, and electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the electrode unit 12-3, electrode unit 12-8, electrode unit 12-1, and electrode unit 12-2. 3. The dielectric elements 15 of the four electrode units 12 of electrode unit 12-18 and the signal end 14-2 of the temperature sensor 14 of the four electrode units 12; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the four electrode units 12 of electrode unit 12-4, electrode unit 12-9, electrode unit 12-14, and electrode unit 12-19 and the signal end 14-2 of the temperature sensor 14 of the four electrode units 12; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the four electrode units 12 of electrode unit 12-5, electrode unit 12-10, electrode unit 12-15, and electrode unit 12-20 and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 and the signal end 14-2 of the temperature sensor 14 of the same column group in parallel and is used to connect to an external device. It should be noted that these dual-purpose signal lines 19 can selectively transmit AC signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 26 and coordinating the closing or opening of the grounding line 18, which will be described in detail below.
[0043] The multiple grounding wires 18 and the multiplexed signal wires 19 are conductive traces embedded in the flexible circuit board 11. The flexible circuit board 11 is electrically connected to the first cable 13. The multiple grounding wires 18 and the multiplexed signal wires 19 embedded in the flexible circuit board 11 are electrically connected to corresponding wires (not shown) in the first cable 13 one by one.
[0044] The tumor electric field treatment system 100 of this embodiment includes at least one pair of the above-mentioned electrode sheets 10, an adapter 20 electrically connected to the electrode sheets 10, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheets 10 and the electric field generator 30. The electric field generator 30 provides an AC signal or a DC signal to the dielectric elements 15 in the multiple electrode units 12 of the electrode sheets 10 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheets 10, and is used to receive the temperature detection signal output by the temperature sensor 14 in the multiple electrode units 12. The adapter 20 is configured to transmit the AC signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheets 10, and is also configured to transmit a DC signal to the dual-purpose signal line 19 of the electrode sheets and receive the temperature detection signal output by the multiple dual-purpose signal line 19 of the electrode sheets 10.
[0045] refer to Figure 3 and Figure 4As shown, the adapter 20 includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of pressure resistors 24 corresponding to the multiple groups of analog-to-digital converters 23, multiple groups of grounding switches 25 and multiple groups of two-way switching switches 26, a first communication unit 27, multiple AC signal lines 28 connected to the multiple groups of two-way switching switches 26 in a one-to-one correspondence, and a first power module 29 connected to the first communication unit 27, the first controller 22 and the multiple groups of analog-to-digital converters 23. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered). Among them, the multiple circuit lines (unnumbered) are electrically connected to the multiple grounding lines 18 and the multiple dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheet 10 through the first cables 13 of the corresponding electrode sheet 10. The multiple circuit lines (not labeled) include multiple AC signal lines 28 that transmit AC signals to the corresponding electrode sheets 10 and are electrically connected to the multiplexed signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheets 10, multiple circuit lines (not labeled) that are electrically connected to the multiplexed signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheets 10 and are used to supply power to each temperature sensor 14 of the electrode sheets 10 or transmit the temperature detection signal of the electrode sheets 10, and multiple circuit lines (not labeled) that are electrically connected to the multiple grounding lines 18 in the flexible circuit board 11 of the corresponding electrode sheets 10. The number P of circuit lines electrically connected between the adapter 20 and one electrode sheet 10 is equal to the sum of the number of rows M and the number of columns N of the electrode units 12 of the electrode sheet 10 plus 1; the number H of circuit lines electrically connected between the adapter 20 and X electrode sheets 10 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 10, that is, H=XP=X*(M+N+1). The number of groups of the grounding switches 25 and the number of groups of the two-way switching switches 26 are both related to the number of electrode sheets 10. The number of groups of the grounding switches 25 is the same as the number of groups of the two-way switching switches 26; and is not less than the number of electrode sheets 10. Preferably, the number of groups of the grounding switches 25 and the number of groups of the two-way switching switches 26 are both the same as the number of electrode sheets 10. The following is a detailed description of the electrical connection between an electrode sheet 10 having 20 electrode units 12 and an adapter 20 as an example.
[0046] Each group of grounding switches 25 is provided with a plurality of grounding switches 25, which are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multi-path grounding lines 18 of the corresponding electrode sheet 10, and are configured to control the conduction or disconnection of the multi-path grounding lines 18. The circuit lines (not numbered) that are electrically connected to the multi-path grounding lines 18 of the electrode sheet 10 are grounded at one end close to the grounding switches 25. The number of grounding switches 25 in each group of grounding switches 25 is related to the number of grounding lines 18 of the flexible circuit board 11 of the corresponding electrode sheet 10, and the two are equal in this embodiment. Figure 3 As shown, in this embodiment, each group of grounding switches 25 is provided with a plurality of grounding switches 25, and in this embodiment, there are four grounding switches 25, namely, a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3 and a fourth grounding switch 25-4. The plurality of grounding switches 25 in each group respectively control the closing or disconnection of the corresponding grounding wire 18 of a corresponding electrode sheet 10. Specifically, the first grounding switch 25-1 is used to control the closing or disconnection of the first grounding wire 18-1 of the corresponding electrode sheet 10, and further can cooperate with the corresponding group of two-way switching switches 26 to control the power on and off of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row group of the electrode sheet 10; the second grounding switch 25-2 is used to control the closing or disconnection of the second grounding wire 18-2 of the electrode sheet 10, and further can cooperate with the corresponding group of two-way switching switches 26 to control the power on and off of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the second row group of the electrode sheet 10. The third grounding switch 25-3 is used to control the closing or disconnection of the third grounding line 18-3 of the electrode sheet 10, and can cooperate with the corresponding group of two-way switching switches 26 to control the power on and off of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-11 to electrode unit 12-15 in the third row group of the electrode sheet 10; the fourth grounding switch 25-4 is used to control the closing or disconnection of the fourth grounding line 18-4 of the electrode sheet 10, and can cooperate with the corresponding group of two-way switching switches 26 to control the power on and off of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-16 to electrode unit 12-20 in the fourth row group of the electrode sheet 10. The above-mentioned grounding switch 25 can be a mechanical switch, such as a relay. The grounding switch 25 can also be an electronic switch, and each grounding switch 25 can be opened and closed by the first controller 22 of the adapter 20.
[0047] In this embodiment, the multiple groups of grounding switches 25 are all electronic switches. The first controller 22 is connected to the multiple groups of grounding switches 25 for sequentially and cyclically controlling the opening and closing states of multiple grounding switches 25 in each group of grounding switches 25, and then sequentially and individually conducting each of the multiple grounding wires 18 of the corresponding electrode sheet 10 and cooperating with the switching of the corresponding bidirectional switch 26, so as to sequentially and time-dividedly collect the temperature of the patient's body surface detected by all temperature sensors 14 on the electrode sheet 10. The number of each group of grounding switches 25 is greater than or equal to the number of grounding wires 18 of the flexible circuit board 11 of the corresponding electrode sheet 10. In this embodiment, the number of each group of grounding switches 25 is the same as the number of grounding wires 18 of the corresponding electrode sheet 10.
[0048] Each set of two-way switches 26 is provided with a plurality of two-way switches 26. The plurality of two-way switches 26 in each set are respectively connected to the adapter 20 and are respectively electrically connected to circuit lines (not numbered) corresponding to the multiplex dual-purpose signal lines 19 of the corresponding electrode sheet 10. The number of two-way switches 26 in each set of two-way switches 26 is related to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10, and is greater than or equal to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10. Figure 3 In the embodiment shown, the two are equal. Each bidirectional switch 26 has two ends 1 and 2, and the acquisition end 1 of the plurality of bidirectional switches 26 in the same group is electrically connected to the corresponding detection channels of the plurality of detection channels of the corresponding group of analog-to-digital converters 23, and the input end 2 of each bidirectional switch 26 in the same group is electrically connected to the corresponding same AC signal line 28. Each bidirectional switch 26 is configured to control the multiplexed signal line 19 to access the corresponding AC signal line 28 to transmit the alternating current signal or to access the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.
[0049] like Figure 3As shown, taking an electrode sheet 10 electrically connected to an adapter 20 as an example, in this embodiment with 20 electrode units 12, the plurality of bidirectional switches 26 are respectively a first bidirectional switch 26-1, a second bidirectional switch 26-2, a third bidirectional switch 26-3, a fourth bidirectional switch 26-4 and a fifth bidirectional switch 26-5. The plurality of bidirectional switches 26 in the same group respectively control the switching of a corresponding one of the multiplexed dual-purpose signal lines 19 of the same electrode sheet 10 between transmitting an alternating current signal and transmitting a temperature detection signal. Specifically, the first bidirectional switch 26-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode sheet 10 between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of each dielectric element 15 of the electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16 in the first column group of the electrode sheet 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16 in the first column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the first column of electrode units 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16 transmit an alternating current signal to the patient or output the temperature collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. The second bidirectional switch 26-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode sheet 10 between transmitting the alternating current signal and transmitting the temperature detection signal, thereby controlling the conduction of each dielectric element 15 of the electrode unit 12-2, electrode unit 12-7, electrode unit 12-12, and electrode unit 12-17 in the second column group of the electrode sheet 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode unit 12-2, electrode unit 12-7, electrode unit 12-12, and electrode unit 12-17 in the second column group, and cooperating with the corresponding grounding switch 25-1, grounding switch 25-2, grounding switch 25-3, and grounding switch 25-4, so that the second column of electrode units 12-2, electrode units 12-7, electrode units 12-12, and electrode units 12-17 transmit alternating current signals to the patient or output the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23;The third bidirectional switch 26-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 10 between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of each dielectric element 15 of the electrode unit 12-3, electrode unit 12-8, electrode unit 12-13, and electrode unit 12-18 in the third column group of the electrode sheet 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode unit 12-3, electrode unit 12-8, electrode unit 12-13, and electrode unit 12-18 in the third column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the third column electrode unit 12-3, electrode unit 12-8, electrode unit 12-13, and electrode unit 12-18 transmit an alternating current signal to the patient or output the temperature detection signal collected by the temperature sensor 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. The fourth bidirectional switch 26-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 10 between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of each dielectric element 15 of the electrode unit 12-4, electrode unit 12-9, electrode unit 12-14, and electrode unit 12-19 in the fourth column group of the electrode sheet 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode unit 12-4, electrode unit 12-9, electrode unit 12-14, and electrode unit 12-19 in the fourth column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the fourth column of electrode units 12-4, electrode units 12-9, electrode units 12-14, and electrode units 12-19 transmit alternating current signals to the patient or output the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23;The fifth bidirectional switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode sheet 10 between transmitting alternating current signals and transmitting temperature detection signals, thereby controlling the conduction of the dielectric elements 15 of the electrode units 12-5, 12-10, 12-15, and 12-20 in the fifth column group of the electrode sheet 10 and the conduction of the signal ends 14-2 of the temperature sensors 14 of the electrode units 12-5, 12-10, 12-15, and 12-20 in the fifth column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the fifth column of electrode units 12-5, 12-10, 12-15, and 12-20 transmit alternating current signals to the patient or output the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. When the input end 2 of each set of two-way switching switches 26 is turned on and the collection end 1 is turned off, an AC signal can be transmitted to the dielectric element 15 of each electrode unit 12 of the corresponding electrode sheet 10. When the collection end 1 of each set of two-way switching switches 26 is turned on and the input end 2 is turned off, it can cooperate with each grounding switch 25 in the corresponding set of grounding switches 25 to transmit the temperature detection signal collected by the temperature sensor 14 of each electrode unit 12 on the electrode sheet 10 in a time-sharing manner. The above-mentioned two-way switching switch 26 can be a mechanical switch, such as a relay. The two-way switching switch 26 can also be an electronic switch, and the switching between the collection end 1 and the input end 2 of each two-way switching switch 26 can be controlled by the first controller 22 of the adapter 20. ;
[0050] In this embodiment, the plurality of sets of two-way switches 26 are all electronic switches. The first controller 22 is in communication connection with the plurality of sets of two-way switches 26, and is used to control the plurality of two-way switches 26 in each set of two-way switches 26 to switch between their respective acquisition terminals 1 and input terminals 2, and to coordinate the closing or opening of the corresponding grounding switch 25, so as to continuously monitor the temperature of the patient's body surface detected by all the temperature sensors 14 on the electrode sheet 10 or transmit an AC signal to the patient.
[0051] In this embodiment, each group of analog-to-digital converters 23 is electrically connected to the collection terminals 1 of the multiple bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26 through the multi-channel circuit lines (unnumbered) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multiplexed signal line 19 of the corresponding electrode sheet 10, and convert the temperature detection signal from an analog signal to a digital signal. Each group of analog-to-digital converters 23 includes multiple detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect a corresponding one-way dual-purpose signal line 19 in the multiplexed signal line 19 through the corresponding bidirectional switching switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switching switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of the electrode units 12 of the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switches 26 in a corresponding group of bidirectional switches 26, which is not less than the number of columns of electrode units 12 of the corresponding electrode sheet 10. Figure 3 As shown, each group of analog-to-digital converters 23 includes a total of 5 detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 through the collection end 1 of the first two-way switch 26-1, the second detection channel B is connected to the second dual-purpose signal line 19-2 through the collection end 1 of the second two-way switch 26-2, the third detection channel C is connected to the third dual-purpose signal line 19-3 through the collection end 1 of the third two-way switch 26-3, the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through the collection end 1 of the fourth two-way switch 26-4, and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 through the collection end 1 of the fifth two-way switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, E is connected to a first power module 29 for providing a detection voltage to the detection channel A, B, C, D, E via a corresponding voltage divider resistor 24 in the adapter 20, and the first power module 29 provides a DC signal.
[0052] In this embodiment, the first communication unit 27 is configured to obtain the digital signals output by the multiple analog-to-digital converters 23 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage, current or power of the AC signal provided to the multiple electrode units 12 of the electrode sheet 10 according to the received digital signals. Exemplarily, when any of the multiple digital signals received exceeds the preset threshold value, it means that the temperature of the human body surface to which the corresponding dielectric element 15 is applied detected by at least one temperature sensor 14 in the electrode sheet 10 exceeds the preset threshold temperature (for example, 41°C, 42°C, etc.), and at this time, the voltage, current or power of the AC signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode unit 12 of the electrode sheet 10 from being too high in temperature when the AC signal is applied, causing low-temperature burns to the patient's skin. The above-mentioned preset threshold temperature and preset threshold value can be determined according to the human safety threshold value. The first communication unit 27 is controlled by the first controller 22 and transmits the digital signals converted by the multiple analog-to-digital converters 23 in series. In this embodiment, the preset temperature threshold may be a value within the range of 36°C-45°C.
[0053] refer to Figure 4 as well as Figure 5 In this embodiment, the first power module 29 is electrically connected to the second power module 31 of the electric field generator 30, and is configured to supply power to the first controller 22, the multiple analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. A first connector 40 is connected between each electrode sheet 10 and the adapter 20, and the first connector 40 is suitable for connecting the corresponding electrode sheet 10 to the adapter 20. Figure 1 As shown, the first connector 40 includes a first plug 41 provided at an end of the first cable 13 away from the electrode sheet 10 and a first socket 42 provided on the adapter 20. The first plug 41 and the first socket 42 are push-type spring connectors, that is, the first connector 40 uses a connector to connect the adapter 20 with the electrode sheet 10. Each first cable 13 has five wires electrically connected to the two-way switches 26-1, 26-2, 26-3, 26-4, and 26-5 in the corresponding group of two-way switches 26, and four wires electrically connected to the grounding switches 25-1, 25-2, 25-3, and 25-4 in the corresponding group of grounding switches 25. That is, each first connector 40 is electrically connected to a corresponding group of two-way switches 26 and a corresponding group of grounding switches 25 of the adapter 20 through nine wires; and is connected to the electric field generator 30 through a corresponding AC signal line 28 of the adapter 20.
[0054] A second connector 50 is provided between the adapter 20 and the electric field generator 30, and the second connector 50 is suitable for connecting the electric field generator 30 to the adapter 20. The adapter 20 also includes a second cable 21 connected to the second connector 50. The second connector 50 includes a second plug 51 provided at an end of the second cable 21 away from the first controller 22 and a second socket 52 provided on the electric field generator 30. The second plug 51 and the second socket 52 are press-type spring connectors, that is, the second connector 50 uses a connector to connect the adapter 20 to the electric field generator 30. Each first connector 40, such as X1, Y1, X2, and Y2, is connected to the second connector 50 through a corresponding AC signal line 28. The first connectors 40, such as X1, Y1, X2, and Y2, are connected to a corresponding set of grounding switches 25 and a corresponding set of analog-to-digital converters 23. Specifically, each first connector 40 is simultaneously connected to the second connector 50 and a corresponding set of analog-to-digital converters 23 through a corresponding set of bidirectional switching switches 26. Taking four electrode sheets 10 as an example, the second cable 21 has eight conductors, which are four conductors 1 to 4 electrically connected to the corresponding AC signal lines 28 and used to transmit AC signals, a conductor 5 electrically connected to the data receiving line RX of the first communication unit 27, a conductor 6 electrically connected to the data sending line TX of the first communication unit 27, a conductor 7 electrically connected to the VCC power line of the first power module 29, and a conductor 8 electrically connected to the GND line of the first power module 29. The second connector 50 is connected to the first communication unit 27 through the data receiving line RX and the data sending line TX, the VCC pin of the second connector 50 is connected to the VVC power line of the first power module 29, the GND pin of the second connector 50 is connected to the GND line of the first power module 29 and grounded, and the VCC pin of the second connector 50 is also connected to the corresponding group of voltage dividers 24 and the corresponding group of analog-to-digital converters 23 through the VCC power line of the first power module 29.
[0055] refer to Figure 5The electric field generator 30 includes: a second power module 31, a second controller 32, an AC signal generator 34, a second communication unit 33 and a set of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected to the VCC power line of the second power module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power module 31. The second power module 31 is also connected to the second controller 32 and the AC signal generator 34 and supplies power to them. The second communication unit 33 is electrically connected to the wire 5 of the second connector 50 through its data receiving line RX and is electrically connected to the wire 6 of the second connector 50 through its data sending line TX, thereby realizing information interaction between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected to the second communication unit 33, the AC signal generator 34 and a set of AC signal switches 35 at the same time. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in a group of AC signal switches 35 and adjust the relevant parameters of the AC signal applied by the AC signal generator 34 according to the relevant digital signal received from the adapter 20 by the second communication unit 33. The AC signal generator 34 is electrically connected to the wires 1 to 4 for transmitting the AC signal of the second connector 50 through a group of AC signal switches 35. A group of AC signal switches 35 includes a plurality of AC signal switches 35, and the plurality of AC signal switches 35 are arranged in a one-to-one correspondence with the plurality of electrode sheets 10. Each AC signal switch 35 is electrically connected to a corresponding wire 1, 2, 3, 4 for transmitting the AC signal in the second connector 50 through an AC signal connection 36 and is electrically connected to the corresponding electrode sheet 10 through the corresponding wires 1, 2, 3, 4 of the second connector 50, so as to transmit the AC signal to each electrode sheet 10. The AC signal generator 34 is electrically connected to the group of AC signal switches 35 through a group of AC signal connections 36.
[0056] Specifically, the number of AC signal switches 35 of the electric field generator 30 is related to the number of electrode sheets 10. In this embodiment, the number of AC signal switches 35 is equal to the number of electrode sheets 10 and both are 4. The AC signal switch 35 includes a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, and a fourth AC signal switch 35-4, which are electrically connected to the wires 1 to 4 of the second connector 50 through the corresponding AC signal wiring 36, respectively, one by one.One end of the first AC signal switch 35-1 is electrically connected to the AC signal generator 34 through the first AC signal connection 36-1 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 1 for transmitting AC signals in the second connector 50 through the first AC signal connection 36-1 and is electrically connected to the AC signal line 28 at the port X1 of the adapter 20 through the wire 1 of the second connector 50, the AC signal line 28 at the port X1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 transmits an AC signal to the electrode sheet 10 electrically connected to the port X1 of the adapter 20; One end of the second AC signal switch 35-2 is electrically connected to the AC signal generator 34 through the second AC signal connection 36-2 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 2 for transmitting AC signals in the second connector 50 through the second AC signal connection 36-2 and is electrically connected to the AC signal line 28 at the port Y1 of the adapter 20 through the wire 2 of the second connector 50, the AC signal line 28 at the port Y1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 transmits AC signals to the electrode sheet 10 electrically connected to the port Y1 of the adapter 20; One end of the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 through the third AC signal connection 36-3 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 3 for transmitting AC signals in the second connector 50 through the third AC signal connection 36-3 and is electrically connected to the AC signal line 28 at the port X2 of the adapter 20 through the wire 3 of the second connector 50, the AC signal line 28 at the port X2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 transmits an AC signal to the electrode sheet 10 electrically connected to the port X2 of the adapter 20; One end of the fourth AC signal switch 35-4 is electrically connected to the AC signal generator 34 through the fourth AC signal connection 36-4 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 4 for transmitting AC signals in the second connector 50 through the fourth AC signal connection 36-4 and electrically connected to the AC signal line 28 at the port Y2 of the adapter 20 through the conductor 4 of the second connector 50, the AC signal line 28 at the port Y2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 transmits AC signals to the electrode sheet 10 electrically connected to the port Y1 of the adapter 20.
[0057] The following will refer to Figures 3 to 5 The working principle of the tumor electric field treatment system 100 of this embodiment is described in detail.
[0058] Specifically, when it is necessary to detect the temperature of each electrode unit 12 of a certain electrode sheet 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the collection end 1 of each of the multiple bidirectional switching switches 26 of a group of bidirectional switching switches 26 electrically connected to the electrode sheet 10 to be turned on and the input end 2 to be turned off, so as to disconnect the AC signal applied to the electrode sheet 10; at the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each of the grounding switches 25 in a group of grounding switches 25 electrically connected to the electrode sheet 10 to be turned on in sequence in a time-sharing manner. At this time, the temperature detection signals collected by each temperature sensor 14 of each electrode unit 12 of each row group of the electrode sheet 10 can be collected in a time-sharing manner in sequence through multiple detection channels A, B, C, D, and E of a group of analog-to-digital converters 23 corresponding to the electrode sheet 10. Each detection channel A, B, C, D, E of each group of analog-to-digital converters 23 only collects the temperature detection signal of the temperature sensor 14 of the corresponding electrode unit 12 in each electrode unit 12 of the electrode sheet 10 in the same row group at the same time, and the above temperature detection signal can be represented by a voltage value. Among the four grounding switches 25 in a group of grounding switches 25 corresponding to the electrode sheet 10, only one grounding switch 25 can be turned on at the same time, and the other three are turned off. All five bidirectional switching switches 26 in a group of bidirectional switching switches 26 corresponding to the group of analog-to-digital converters 23 are switched to their respective collection terminals 1 so that each dual-purpose signal line 19 of the electrode sheet 10 is electrically connected to the corresponding detection channel A, B, C, D, E of the corresponding group of analog-to-digital converters 23 in a one-to-one correspondence and turned on. In this way, the group of analog-to-digital converters 23 can collect the voltage value of the temperature sensor 14 of each electrode unit 12 in the same row group that is short-circuited with one grounding line 18 corresponding to the turned-on grounding switch 25.
[0059] Specifically, when the first grounding switch 25-1 is closed, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 are all opened, and the first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 are all switched to their respective collection terminals 1, the temperature sensors 14 of the electrode units 12-1 to 12-5 of the first row group are powered on, and the temperature sensors 14 of the electrode units 12-6 to 12-20 of the remaining row groups are powered off, and the first detection channel A in the group of analog-to-digital converters 23 short-circuits the electrode units 12-1, 12-6, 12-11 and 12-16, respectively. The signal end 14-2 of the temperature sensor 14 of the electrode unit 12-1 is connected to the ground, and the ground ends 14-1 of the temperature sensors 14 of the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16 are disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, and the remaining temperature sensors 14 located in the first row will not affect the resistance value of the temperature sensor 14 of the electrode unit 12-1. Therefore, only the temperature sensor 14 of the electrode unit 12-1 is effectively operated on the first detection channel A of the group of analog-to-digital converters 23, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-1. Similarly, the voltage value collected on the second detection channel B in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-2. The voltage value collected on the third detection channel C in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-3. The voltage value collected on the fourth detection channel D in the set of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-4. The voltage value collected on the fifth detection channel E in the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-5.
[0060] When the second grounding switch 25-2 is closed, the first grounding switch 25-1, the third grounding switch 25-3 and the fourth grounding switch 25-4 are all opened, and the first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 are all switched to their respective collection terminals 1, the temperature sensors 14 of the electrode units 12-6 to 12-10 of the second row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-5 and the electrode units 12-11 to 12-20 of the remaining row groups are powered off, and the first detection channel A in the group of analog-to-digital converters 23 short-circuits the electrode units 12-1, 12-6, 12-11, and 12-20. As for the signal end 14-2 of the temperature sensor 14 of each of the electrode unit 12-16, since only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-6 is connected to the ground, and the ground ends 14-1 of the temperature sensors 14 of the electrode unit 12-1, the electrode unit 12-11, and the electrode unit 12-16 are disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 located in the second row will not affect the resistance value of the temperature sensor 14 of the electrode unit 12-6, so only the temperature sensor 14 of the electrode unit 12-6 is effectively operated on the first detection channel A of the group of analog-to-digital converters 23, and at this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-6. Similarly, the voltage value collected on the second detection channel B in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-7. The voltage value collected on the third detection channel C in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-8. The voltage value collected on the fourth detection channel D in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-9. The voltage value collected on the fifth detection channel E in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-10.
[0061] When the third grounding switch 25-3 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the fourth grounding switch 25-4 are all opened, and the first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 are all switched to their respective collection terminals 1, the temperature sensors 14 of the electrode units 12-11 to 12-15 of the third row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-10 and the electrode units 12-16 to 12-20 of the remaining row groups are powered off, and the first detection channel A in the group of analog-to-digital converters 23 short-circuits the electrode units 12-1, 12-6, 12-11, and 12-20. As for the signal end 14-2 of the temperature sensor 14 of each of the electrode unit 12-16, since only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-11 is connected to the ground, and the ground ends 14-1 of the temperature sensors 14 of the electrode unit 12-1, the electrode unit 12-6, and the electrode unit 12-16 are disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 located in the third row will not affect the resistance value of the temperature sensor 14 of the electrode unit 12-11, so only the temperature sensor 14 of the electrode unit 12-11 is effectively operated on the first detection channel A of the group of analog-to-digital converters 23, at this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-11. Similarly, the voltage value collected on the second detection channel B in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-12. The voltage value collected on the third detection channel C in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-13. The voltage value collected on the fourth detection channel D in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-14. The voltage value collected on the fifth detection channel E in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-15.
[0062] When the fourth grounding switch 25-4 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 are all opened, and the first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 are all switched to their respective collection terminals 1, the temperature sensors 14 of the electrode units 12-16 to 12-20 of the fourth row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-15 of the remaining row groups are powered off, and the first detection channel A in the group of analog-to-digital converters 23 short-circuits the temperature sensors of the electrode units 12-1, 12-6, 12-11 and 12-16. Since only the grounding terminal 14-1 of the temperature sensor 14 of the electrode unit 12-16 is connected to the ground, and the grounding terminals 14-1 of the temperature sensors 14 of the electrode unit 12-1, the electrode unit 12-6, and the electrode unit 12-11 are disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 located in the fourth row will not affect the resistance value of the temperature sensor 14 of the electrode unit 12-16. Therefore, only the temperature sensor 14 of the electrode unit 12-16 is effectively operated on the first detection channel A of the group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-16. Similarly, the voltage value collected on the second detection channel B in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-17. The voltage value collected on the third detection channel C in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-18. The voltage value collected on the fourth detection channel D in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-19. The voltage value collected on the fifth detection channel E in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-20. Thus, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 can collect the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of a certain electrode sheet 10 by controlling a group of bidirectional switching switches 26 and a group of grounding switches 25 that are electrically connected to the electrode sheet 10. Similarly, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of other electrode sheets 10 can be obtained.
[0063] The first controller 22, the plurality of analog-to-digital converters 23, and the plurality of bidirectional switches 26 can automatically perform operations through pre-programmed program codes. For example, the first controller 22 first controls all the bidirectional switches 26 in the corresponding group of bidirectional switches 26 to switch to the collection end 1 so that the collection ends 1 of the bidirectional switches 26 are all turned on and the input ends 2 are all turned off so that the dual-purpose signal lines 19 of the corresponding electrode sheet 10 are electrically connected to the corresponding group of analog-to-digital converters 23, and then closes the first grounding switch 25-1 in the corresponding group of grounding switches 25, and disconnects the remaining second grounding switches 25-2, third grounding switches 25-3 to fourth grounding switches 25-4 in the group of grounding switches 25. During this period, the group Each detection channel A, B, C, D, E of the analog-to-digital converter 23 obtains the temperature detection signal of each temperature sensor 14 of each electrode unit 12 located in the first row group in the corresponding electrode sheet 10 and converts it into a digital signal and stores it in a separately set memory. Then, after a preset interval, the first controller 22 closes the second grounding switch 25-2 in the group of grounding switches 25 and disconnects the first grounding switch 25-1, the third grounding switch 25-3 and the fourth grounding switch 25-4 in the group of grounding switches 25. During this period, each detection channel A, B, C, D, E of the group of analog-to-digital converters 23 obtains the temperature detection signal of each temperature sensor 14 of each electrode unit 12 located in the second row group. In this way, each grounding switch 25 in the group of grounding switches 25 is turned on separately in turn, and the temperature detection signal of all the temperature sensors 14 in each row group of the electrode sheet 10 can be obtained. Similarly, the temperature detection signal of all the temperature sensors 14 on at least one pair of electrode sheets 10 is obtained through this operation.
[0064] The tumor electric field therapy system 100 of the present application can realize real-time and comprehensive monitoring of the temperature of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 or the core of the first cable 13 electrically connected to the electrode sheet 10, and then determine whether the electrode sheet 10 is qualified based on the obtained temperature detection signal; or determine whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14 obtained; or if the electrode sheet is qualified, identify the type of the electrode sheet based on the obtained temperature detection signal; or if the electrode sheet is qualified, determine whether the electrode unit 12 of the electrode sheet 10 is over-temperature based on the obtained temperature detection signal, and then control the alternating electric signal applied to the electrode sheet 10 or the electrode unit 12 of the corresponding column of the electrode sheet 10, so as to avoid low-temperature burns on the patient's body surface when the electrode sheet 10 is used for tumor treatment. In addition, the flexible circuit board 11 of the electrode sheet 10 of the present application is electrically connected to the dielectric element 15 of the same electrode unit 12 and the signal end 14-2 of the temperature sensor 14 through the same dual-purpose signal line 19. While it can transmit both AC signals and DC signals for temperature signal collection and collected temperature detection signals through the dual-purpose signal line 19, it also greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) arranged thereon, reduces the wiring difficulty of the flexible circuit board 11, simplifies the manufacturing process, reduces the weight of the flexible circuit board 11, and reduces the manufacturing cost. The electrode sheet 10 of the present application can also switch between applying AC signals for tumor treatment and transmitting DC signals for temperature collection and transmitting collected temperature detection signals through the combined control of the grounding switch 25 electrically connected to the grounding line 18 arranged thereon and the bidirectional switching switch 26 electrically connected to the dual-purpose signal line 19.
[0065] When it is necessary to apply an alternating current signal to the patient through the electrode units 12 of a certain electrode sheet 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls all the grounding switches 25 in a group of grounding switches 25 corresponding to the electrode sheet 10 to be disconnected, and at the same time controls all the bidirectional switching switches 26 in a group of bidirectional switching switches 26 corresponding to the electrode sheet 10 to be switched to their respective input ends 2, so that the collection ends 1 of the bidirectional switching switches 26 are all disconnected and the input ends 2 are all turned on, so that all the dual-purpose signal lines 19 of the electrode sheet 10 are electrically connected to an AC signal line 28 corresponding to the adapter 20 and the electrode sheet 10, thereby transmitting the alternating current signal to the electrode units 12 of the electrode sheet 10.When the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of the electrode sheet 10 are far lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32 to continue to generate an AC signal with an increased voltage or current amplitude or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 10 through a corresponding AC signal line 28 of the adapter 20, so that the pair of electrode sheets 10 continue to apply the AC signal; when the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of the electrode sheet 10 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32 to continue to generate an AC signal with an increased voltage or current amplitude or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 10 through a corresponding AC signal line 28 of the adapter 20, so that the pair of electrode sheets 10 continue to apply the AC signal. The field generator 30 can reduce the voltage or current of the alternating current signal generated by the AC signal generator 34 through the second controller 32, thereby reducing the voltage or current of the alternating current signal applied to the pair of electrode sheets 10; when it is detected that the temperature detection signal of the temperature sensor 14 of an electrode unit 12 in a certain electrode sheet 10 is greater than a preset temperature threshold, the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode sheet 10 to disconnect through the second controller 32 to stop applying the alternating current signal to the electrode sheet 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all the bidirectional switching switches in a group of bidirectional switching switches 26 electrically connected to the electrode sheet 10 26 are all switched from their input end 2 to the collection end 1, that is, the collection ends 1 of all the two-way switching switches 26 of a group of two-way switching switches 26 electrically connected to the electrode sheet 10 are all turned on and the input ends 2 are all turned off, thereby stopping the application of the alternating electric signal to the electrode sheet 10; or, when it is detected that the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode sheet 10 is greater than the preset temperature threshold, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode sheet 10 to continue to be turned on, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a two-way switching switch 14 electrically connected to the electrode unit 12 of the electrode sheet 10 to be turned on. The switch 26 is switched from its input end 2 to its collection end 1, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 simultaneously controls the input ends 2 of the remaining bidirectional switches 26 electrically connected to the electrode units 12 whose temperature detection signals of the electrode sheet 10 do not exceed the preset temperature threshold and are in different columns from the electrode units 12 whose temperature detection signals exceed the preset temperature threshold to continue to maintain electrical connection, so as to stop applying the AC signal to all the electrode units 12 in the column where the electrode units 12 whose temperature detection signals of the electrode sheet 10 exceed the preset temperature threshold are located, and continue to apply the AC signal to the electrode units 12 in the remaining columns whose temperature detection signals of the electrode sheet 10 do not exceed the preset temperature threshold. In this way, the control method of applying the AC signal of the temperature detection signal to different regions of the tumor electric field treatment system 100 is realized.When an AC signal is applied, all grounding switches 25 are opened.
[0066] In the embodiment of the present application, the grounding switch 25 electrically connected to the multi-way grounding wires 18 of the electrode sheet 10 and the bidirectional switch 26 electrically connected to the multi-way dual-purpose signal wires 19 of the electrode sheet 10 are both provided in the adapter 20. However, in other embodiments, the grounding switch 25 electrically connected to the grounding wire 18 and the bidirectional switch 26 electrically connected to the dual-purpose signal wire 19 can also be provided on the electrode sheet 10 or provided in the electric field generator 30, which will not be described in detail here. In addition, the analog-to-digital converter 23 provided in the adapter 20 can also be provided in the electric field generator 30 and directly controlled by the second controller 32.
[0067] The present application also provides other embodiments of the electrode sheet 10 , and the differences among the multiple embodiments are mainly the different numbers of electrode units 12 and / or the different electrical connection arrangements of the electrode units 12 , which will be described below.
[0068] refer to Figure 6As shown, the electrode sheet 10A of the second embodiment is provided with 19 electrode units 12, and the flexible circuit board 11A arranges the 19 electrode units 12 into four rows and five columns in terms of electrical connection, wherein each of the three rows has five electrode units 12, and the remaining row has four electrode units 12. The electrode sheet 10A includes four grounding wires 18 and five dual-purpose signal wires 19, each of which is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of the electrode sheet 10A include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-19. Specifically, the first grounding line 18-1 is used to ground the grounding end 14-1 of the temperature sensor 14 of the five electrode units 12 from the electrode unit 12-1 to the electrode unit 12-5 in the first row group; the second grounding line 18-2 is used to ground the grounding end 14-1 of the temperature sensor 14 of the five electrode units 12 from the electrode unit 12-6 to the electrode unit 12-10 in the second row group; the third grounding line 18-3 is used to ground the grounding end 14-1 of the temperature sensor 14 of the five electrode units 12 from the electrode unit 12-11 to the electrode unit 12-15 in the third row group; the fourth grounding line 18-4 is used to ground the grounding end 14-1 of the temperature sensor 14 of the four electrode units 12 from the electrode unit 12-16 to the electrode unit 12-19 in the fourth row group. In short, each grounding line 18 short-circuits the grounding end 14-1 of the temperature sensor 14 of all the electrode units 12 in each row group and grounds them.
[0069] The five dual-purpose signal lines 19 of the electrode sheet 10A include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, and the electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the electrode unit 12-3, the electrode unit 12-8, and the electrode unit 12-9, and the signal end 14-2 of the temperature sensor 14 One end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the four electrode units 12, electrode unit 12-13, electrode unit 12-18, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the four electrode units 12, electrode unit 12-4, electrode unit 12-9, electrode unit 12-14, and electrode unit 12-19, and the signal end 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the three electrode units 12, electrode unit 12-5, electrode unit 12-10, and electrode unit 12-15, and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 in the same column group and the signal end 14-2 of the temperature sensor 14 in parallel and is used to connect to the adapter 20.
[0070] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 of the adapter 20 are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3 and the fourth grounding line 18-4 of the electrode sheet 10A through the first connector 40A. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 on the adapter 20 are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 of the electrode sheet 10A through the first connector 40A. The working mode of the tumor electric field therapy system formed by the electrode sheet 10A, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each of the grounding switches 25 in turn.
[0071] refer to Figure 7As shown, the electrode sheet 10B of the third embodiment is provided with 17 electrode units 12, and the flexible circuit board 11B arranges the 17 electrode units 12 into four rows and five columns in terms of electrical connection, wherein each of the three rows has five electrode units 12, and the remaining row has two electrode units 12. The electrode sheet 10B includes four grounding wires 18 and five dual-purpose signal wires 19, each of which is used to ground the grounding end 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in each column group and the signal end 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of the electrode sheet 10B include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 and 12-17. Specifically, the first grounding line 18-1 is used to ground the grounding end 14-1 of the temperature sensor 14 of the five electrode units 12 from the electrode unit 12-1 to the electrode unit 12-5 in the first row group; the second grounding line 18-2 is used to ground the grounding end 14-1 of the temperature sensor 14 of the five electrode units 12 from the electrode unit 12-6 to the electrode unit 12-10 in the second row group; the third grounding line 18-3 is used to ground the grounding end 14-1 of the temperature sensor 14 of the five electrode units 12 from the electrode unit 12-11 to the electrode unit 12-15 in the third row group; the fourth grounding line 18-4 is used to ground the grounding end 14-1 of the temperature sensor 14 of the two electrode units 12 from the electrode unit 12-16 to the electrode unit 12-17 in the fourth row group. In short, each grounding line 18 short-circuits the grounding end 14-1 of the temperature sensor 14 of all the electrode units 12 in the corresponding row group and grounds them.
[0072] The five dual-purpose signal lines 19 of the electrode sheet 10B include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, and the electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-3, the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14 The first two-way dual-purpose signal line 19 is connected to the dielectric element 15 of the three electrode units 12, namely, the electrode unit 12-8 and the electrode unit 12-13, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric element 15 of the three electrode units 12, namely, the electrode unit 12-4, the electrode unit 12-9 and the electrode unit 12-14, and the signal end 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of the three electrode units 12, namely, the electrode unit 12-5, the electrode unit 12-10 and the electrode unit 12-15, and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 of each electrode unit 12 and the signal end 14-2 of the temperature sensor 14 in parallel and is used to connect to the adapter 20.
[0073] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 of the adapter 20 are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3 and the fourth grounding line 18-4 of the electrode sheet 10B through the first connector 40B. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 on the adapter 20 are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 of the electrode sheet 10B through the first connector 40B. The working mode of the tumor electric field therapy system formed by the electrode sheet 10B, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each grounding switch 25 in turn.
[0074] refer to Figure 8As shown, the electrode sheet 10C of the fourth embodiment is provided with 17 electrode units 12 like the electrode sheet 10B of the third embodiment, but the specific circuit connection arrangement of each electrode unit 12 is different. The flexible circuit board 11C of the electrode sheet 10C also arranges the 17 electrode units 12 into four rows and five columns in terms of electrical connection, but one row has five electrode units 12, and each of the remaining three rows has four electrode units 12. The electrode sheet 10C includes four grounding wires 18 and five dual-purpose signal wires 19, each of which is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of the electrode sheet 10C include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-9, the third row group includes electrode units 12-10 to 12-13, and the fourth row group includes electrode units 12-14 to 12-17. Specifically, the first grounding line 18-1 is used to ground the grounding end 14-1 of the temperature sensor 14 of the five electrode units 12 from the electrode unit 12-1 to the electrode unit 12-5 in the first row group; the second grounding line 18-2 is used to ground the grounding end 14-1 of the temperature sensor 14 of the four electrode units 12 from the electrode unit 12-6 to the electrode unit 12-9 in the second row group; the third grounding line 18-3 is used to ground the grounding end 14-1 of the temperature sensor 14 of the four electrode units 12 from the electrode unit 12-10 to the electrode unit 12-13 in the third row group; the fourth grounding line 18-4 is used to ground the grounding end 14-1 of the temperature sensor 14 of the four electrode units 12 from the electrode unit 12-14 to the electrode unit 12-17 in the fourth row group. In short, each grounding line 18 short-circuits the grounding end 14-1 of the temperature sensor 14 of all the electrode units 12 in the corresponding row group and grounds them.
[0075] The five dual-purpose signal lines 19 of the electrode sheet 10C include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4 and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-10 and the electrode unit 12-14, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-11 and the electrode unit 12-15, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-3, the electrode unit 12-6, the electrode unit 12-10 and the electrode unit 12-14, and the signal end 14-2 of the temperature sensor 14 The dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-8, electrode unit 12-12, and electrode unit 12-16, and the signal terminals 14-2 of the temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-4, electrode unit 12-9, electrode unit 12-13, and electrode unit 12-17, and the signal terminals 14-2 of the temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of an electrode unit 12 of electrode unit 12-5 and the signal terminal 14-2 of its temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 in the same column group and the signal terminals 14-2 of the temperature sensors 14 in parallel and is used to connect to the adapter 20.
[0076] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 of the adapter 20 are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3 and the fourth grounding line 18-4 of the electrode sheet 10C through the first connector 40C. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 of the adapter 20 are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 of the electrode sheet 10C through the first connector 40C. The working mode of the tumor electric field therapy system formed by the electrode sheet 10C, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each of the grounding switches 25.
[0077] refer to Fig. 9 FIG. 1 is a tumor electric field treatment system 100D according to a fifth embodiment of the present application. Figure 1 The difference between the tumor electric field treatment system 100 described in the embodiment is that the embodiment adopts the electrode sheet 10D of the fifth embodiment and Figure 1 The adapter 20 shown in the figure is electrically connected to the electric field generator 30. There are also four electrode sheets 10D in this embodiment, which are respectively plugged into the first socket 42 of the adapter 20 through the first plug 41D provided at the end of each first cable 13D. Each electrode sheet 10D also includes a plurality of electrode units 12D that are both axially symmetrically arranged and centrally arranged, a plurality of connecting portions 111D located between adjacent electrode units 12, and a wiring portion 112D that is electrically connected to the first cable 13D; however, the wiring portion 112D is extended from an electrode unit 12 toward the outside of the electrode array (not numbered) and is arranged perpendicularly to a connecting portion 111D. The first cable 13D has 8-core wires.
[0078] The electrode unit 12D of the electrode sheet 10D has the same structure as the electrode unit 12 in the aforementioned embodiment, the only difference being that the number of electrode units 12 in this embodiment is 13, and they are arranged in five rows and five columns in space. Specifically, two electrode units 12 are provided in each of the first row and the last row, and are located in the second column and the fourth column respectively; three electrode units 12 are provided in each of the three middle rows, and the three electrode units 12 in each row are located in the first column, the third column, and the fifth column respectively. There are three electrode units 12 located in the center of the electrode array (unnumbered), namely, three electrode units 12 located in the second row and the third column, the third row and the third column, and the third row and the third column, and the rest are electrode units 12 located at the periphery of the electrode array (unnumbered). Two adjacent electrode units 12 in the periphery are connected via the connection portion 111D. The electrode units 12 in the second row and third column are connected to the electrode units 12 in the first row and second row and adjacent thereto via the connection portion 111D. The electrode units 12 in the fourth row and third column are connected to the electrode units 12 in the fourth row and fifth row and adjacent thereto via the connection portion 111D. The electrode units 12 in the third row and third column are also connected to the electrode units 12 adjacent thereto in the row direction and in the column direction via the connection portion 111D. The electrode units 12 in the periphery are connected in pairs via the connection portion 111D to form an octagonal ring structure.
[0079] Fig.10 (A) Fig. 9 A modified embodiment of the electrode sheet 10D is shown in FIG. 1 , wherein the electrode unit 12D′ of the electrode sheet 10D′ in this embodiment is Fig. 9The electrode units 12D of the electrode sheet 10D shown in the figure are identical in spatial arrangement, and the connection portion 111D' connected to the electrode unit 12D' located in the center is also identical, with the only difference being that: in the electrode sheet 10D' in the modified embodiment, two adjacent electrode units 12D' partially located at the periphery are connected by the connection portion 111D'; and two adjacent electrode units 12D' partially located at the periphery are arranged in a disconnected state, and no connection portion 111D' is provided. Specifically, the two electrode units 12D' located in the first row are arranged in a disconnected state, the two electrode units 12D' located in the last row are arranged in a disconnected state, the two electrode units 12D' located in the first column of the second row and the two electrode units 12D' located in the second column of the first row are arranged in a disconnected state, the two electrode units 12D' located in the first column of the third row and the two electrode units 12D' located in the first column of the fourth row are arranged in a disconnected state, the two electrode units 12D' located in the fifth column of the second row and the two electrode units 12D' located in the fifth column of the third row are arranged in a disconnected state, and the two electrode units 12D' located in the fifth column of the fourth row and the two electrode units 12D' located in the fourth column of the fifth row are arranged in a disconnected state. A first gap D1' is formed between two electrode units 12D' located in adjacent columns and arranged in a disconnected state, and a second gap D2' is formed between two electrode units 12D' located in adjacent rows and arranged in a disconnected state. The first gap D1' and the second gap D2' can prevent the electrode sheet 10D' from wrinkling during application, which affects the overall attachment effect of the electrode sheet.
[0080] Fig.10 (B) with Fig.10 (A) is similar, which is also Fig. 9 A modified embodiment of the electrode sheet 10D is shown in FIG. 1 , wherein the electrode unit 12D" of the electrode sheet 10D" in this embodiment is Fig. 9 The electrode units 12D of the electrode sheet 10D shown in the figure are identical in spatial arrangement, with the only difference being that: in the electrode sheet 10D" in the variation embodiment, the two electrode units 12D" in the first row are arranged in a disconnected state, the two electrode units 12D" in the last row are arranged in a disconnected state, the two electrode units 12D" in the second row and the first column are arranged in a disconnected state with the two electrode units 12D" in the second row and the third column are arranged in a disconnected state, and the two electrode units 12D' in the fourth row and the third column are arranged in a disconnected state with the two electrode units 12D' in the fourth row and the fifth column are arranged in a disconnected state.
[0081] Fig.11 For use Fig. 9 The electrode sheet 10D of the fifth embodiment of the tumor electric field treatment system 100D or its alternative embodiments 10D', 10D" and Figure 1, which is a schematic diagram of the circuit connection of the adapter 20 of the first embodiment shown in . The following circuit description is made by taking the electrode sheet 10D in the fifth embodiment as an example. In terms of electrical connection, the flexible circuit board 11D of the electrode sheet 10D arranges the 13 electrode units 12 into three rows and five columns, wherein two rows each have five electrode units 12, and the remaining row has three electrode units 12. The electrode sheet 10D includes three grounding wires 18 and five dual-purpose signal wires 19, each of which is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric elements 15 of each electrode unit 12 in each column group and the signal terminals 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting alternating current signals.
[0082] The three grounding wires 18 of the electrode sheet 10D are respectively a first grounding wire 18-1, a second grounding wire 18-2 and a third grounding wire 18-3. In the three row groups of the electrode sheet 10D, the first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, and the third row group includes electrode units 12-11 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-6 to 12-10 in the second row group; and the third grounding wire 18-3 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-11 to 12-13 in the third row group. In short, each grounding line 18 short-circuits the grounding terminals 14 - 1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group and connects them to ground.
[0083] The five dual-purpose signal lines 19 of the electrode sheet 10D include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the three electrode units 12, the electrode unit 12-1, the electrode unit 12-6, and the electrode unit 12-11, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the three electrode units 12, the electrode unit 12-2, the electrode unit 12-7, and the electrode unit 12-12, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the electrode unit 12-3, the electrode unit 12-6, and the electrode unit 12-11, and the signal end 14-2 of the temperature sensor 14 The first two-way dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12, electrode unit 12-8, and electrode unit 12-13, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-4 and electrode unit 12-9, and the signal end 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-5 and electrode unit 12-10, and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 and the signal end 14-2 of the temperature sensor 14 in parallel and is used to connect to the adapter 20.
[0084] The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 of the adapter 20 are electrically connected to the first grounding line 18-1, the second grounding line 18-2 and the third grounding line 18-3 of the electrode sheet 10D through the first connector 40D, and the fourth grounding switch 25-4 is in an idle disconnected state. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 of the adapter 20 are electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 of the electrode sheet 10D through the first connector 40D.
[0085] The working mode of the tumor electric field treatment system formed by the electrode sheet 10D, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switching switches 26 are turned on and the collection terminals 1 are turned off, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 are connected to the AC signal. When the collection terminals 1 of all bidirectional switching switches 26 are turned on and the input terminals 2 are turned off, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of the row groups can be obtained in sequence by turning on the grounding switches 25 in sequence. Among them, no operation is required for the grounding switches 25 in the idle disconnected state.
[0086] Fig.12 Shown Fig. 9 The electrode sheet 10D of the fifth embodiment shown in FIG. Fig.10 The electrode sheets 10D', 10D" shown in FIG. Figure 1 Another circuit connection diagram of the adapter 20 of the first embodiment is shown in FIG. The flexible circuit board 11E of the electrode sheet 10E in this embodiment also arranges the 13 electrode units 12 into three rows and five columns in terms of electrical connection, but two rows each have four electrode units 12, and the remaining row has five electrode units 12. The electrode sheet 10E also includes three grounding wires 18 and five dual-purpose signal wires 19. Each grounding wire 18 is used to ground the grounding end 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in the same column group and the signal end 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode sheet 10E include a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, and the third row group includes electrode units 12-9 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-5 to 12-8 in the second row group, and the third grounding wire 18-3 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-9 to 12-13 in the third row group. In short, each grounding wire 18 short-circuits the grounding ends 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.
[0087] The five dual-purpose signal lines 19 of the electrode sheet 10E include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the three electrode units 12, the electrode unit 12-1, the electrode unit 12-5, and the electrode unit 12-9, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the three electrode units 12, the electrode unit 12-2, the electrode unit 12-6, and the electrode unit 12-10, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the three electrode units 12, the electrode unit 12-6, and the electrode unit 12-10, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12, the electrode unit 12-1, and the electrode unit 12-20, and the signal end 14-2 of the temperature sensor 14 The first two-way dual-purpose signal line 19-4 is connected to the dielectric element 15 of the three electrode units 12, electrode unit 12-3, electrode unit 12-7, and electrode unit 12-11, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric element 15 of the three electrode units 12, electrode unit 12-4, electrode unit 12-8, and electrode unit 12-12, and the signal end 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of the electrode unit 12-13 and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 of each electrode unit 12 in the same column group and the signal end 14-2 of the temperature sensor 14 in parallel and is used to connect to the adapter 20.
[0088] The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 of the adapter 20 are electrically connected to the first grounding line 18-1, the second grounding line 18-2 and the third grounding line 18-3 of the electrode sheet 10E through the first connector 40E, and the fourth grounding switch 25-4 is in an idle disconnected state. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 of the adapter 20 are electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 of the electrode sheet 10E through the first connector 40E.
[0089] The working mode of the tumor electric field treatment system formed by the electrode sheet 10E, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 are connected to the AC signal. When the collection terminals 1 of all bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of the row groups can be obtained in sequence by turning on the grounding switches 25 in sequence. Among them, no operation is required for the grounding switches 25 in the idle disconnected state.
[0090] Fig.13 and Fig.12 Similarly, it is also used for Fig. 9 The electrode sheet 10D shown in Fig.10 The electrode sheet 10D shown in the figure is a modified embodiment of Figure 1 Another circuit connection diagram of the adapter 20 shown in FIG. Fig.13As shown, the electrode sheet 10F of the tumor electric field treatment system of the seventh embodiment has 13 electrode units 12 like the electrode sheet 10D of the tumor electric field treatment system of the fifth embodiment, but the specific circuit arrangement is different. The flexible circuit board 11F of the electrode sheet 10F arranges the 13 electrode units 12 into four rows and four columns in terms of electrical connection, wherein three rows each have four electrode units 12, and the remaining row has one electrode unit 12. The electrode sheet 10F includes four grounding wires 18 and four dual-purpose signal wires 19, each of which is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in a corresponding column group and the signal terminal 14-2 of each temperature sensor 14, and is used to receive temperature detection signals or transmit AC signals. The four grounding wires 18 of the electrode sheet 10F include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3 and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, and the fourth row group includes electrode unit 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-5 to 12-8 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-9 to 12-12 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of the electrode unit 12-13 in the fourth row group. In short, each grounding wire 18 short-circuits the grounding terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group and grounds them.
[0091] The four dual-purpose signal lines 19 of the electrode sheet 10F include a first dual-purpose signal line 19 - 1 , a second dual-purpose signal line 19 - 2 , a third dual-purpose signal line 19 - 3 , and a fourth dual-purpose signal line 19 - 4 . One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-1, electrode unit 12-5, electrode unit 12-9 and electrode unit 12-13, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the three electrode units 12, namely, electrode unit 12-2, electrode unit 12-6 and electrode unit 12-10, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the three electrode units 12, namely, electrode unit 12-3, electrode unit 12-7 and electrode unit 12-11, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12, namely, electrode unit 12-4, electrode unit 12-8 and electrode unit 12-12, and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 in the same column group and the signal terminals 14 - 2 of the temperature sensors 14 in parallel and is used to connect to the adapter 20 .
[0092] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 of the adapter 20 are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3 and the fourth grounding line 18-4 of the electrode sheet 10F through the first connector 40F. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3 and the fourth two-way switch 26-4 of the adapter 20 are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3 and the fourth two-purpose signal line 19-4 through the first connector 40F, and the fifth two-way switch 26-5 is in an idle disconnected state.
[0093] The working mode of the tumor electric field treatment system formed by the electrode sheet 10F, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switching switches 26 are turned on and the collection terminals 1 are turned off, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 are connected to the AC signal. When the collection terminals 1 of all bidirectional switching switches 26 are turned on and the input terminals 2 are turned off, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of the row groups can be obtained in turn by turning on the grounding switches 25 in sequence. Among them, no operation is required for the bidirectional switching switches 26 in the idle disconnected state.
[0094] Fig.14 and Fig.13 Similarly, it is also used for Fig. 9 The electrode sheet 10D shown in Fig.10 The electrode sheet 10D shown in the figure is a modified embodiment of Figure 1 Another circuit connection diagram of the adapter 20 shown in FIG. Fig.14As shown, the electrode sheet 10G of the tumor electric field treatment system of the eighth embodiment is also provided with 13 electrode units 12, but the specific circuit arrangement is different. The flexible circuit board 11G of the electrode sheet 10G arranges the 13 electrode units 12 into four rows and four columns in terms of electrical connection, wherein each of the three rows has three electrode units 12, and the remaining row has four electrode units 12. The electrode sheet 10G includes four grounding wires 18 and four dual-purpose signal wires 19. Each grounding wire 18 is used to ground the grounding end 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in a corresponding column group and the signal end 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of the electrode sheet 10G include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-3, the second row group includes electrode units 12-4 to 12-6, the third row group includes electrode units 12-7 to 12-9, and the fourth row group includes electrode units 12-10 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-3 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-4 to 12-6 in the second row group, the third grounding wire 18-3 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-7 to 12-9 in the third row group, and the fourth grounding wire 18-4 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-10 to 12-13 in the fourth row group. In short, each grounding line 18 short-circuits the grounding terminals 14 - 1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group and connects them to ground.
[0095] The four dual-purpose signal lines 19 of the electrode sheet 10G include a first dual-purpose signal line 19 - 1 , a second dual-purpose signal line 19 - 2 , a third dual-purpose signal line 19 - 3 , and a fourth dual-purpose signal line 19 - 4 . One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-1, electrode unit 12-4, electrode unit 12-7, and electrode unit 12-10, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-2, electrode unit 12-5, electrode unit 12-8, and electrode unit 12-11, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-3, electrode unit 12-6, electrode unit 12-9, and electrode unit 12-12, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric element 15 of the electrode unit 12-13 and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 in the same column group and the signal terminals 14 - 2 of the temperature sensors 14 in parallel and is used to connect to the adapter 20 .
[0096] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 of the adapter 20 are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3 and the fourth grounding line 18-4 of the electrode sheet 10G through the first connector 40G. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3 and the fourth two-way switch 26-4 of the adapter 20 are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3 and the fourth two-purpose signal line 19-4 through the first connector 40G, and the fifth two-way switch 26-5 is in an idle disconnected state.
[0097] The working mode of the tumor electric field treatment system formed by the electrode sheet 10G, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 are connected to the AC signal. When the collection terminals 1 of all bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of the row groups can be obtained in sequence by turning on the grounding switches 25 in sequence. Among them, no operation is required for the bidirectional switching switches 26 in the idle disconnected state.
[0098] refer to Fig.15 and Fig.16 As shown, the main difference between the tumor electric field treatment system 100H in this embodiment and the tumor electric field treatment system 100 is that the electrode sheet 10H of the ninth embodiment has 9 electrode units 12. In terms of spatial arrangement, the 9 electrode units 12 are arranged in an array of three rows and three columns. In terms of electrical connection, the flexible circuit board 11H of the electrode sheet 10H arranges the 9 electrode units 12 into two rows and five columns, one row has 5 electrode units 12, and the other row has 4 electrode units 12. The electrode sheet 10H includes two grounding wires 18 and five dual-purpose signal wires 19. Each grounding wire 18 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12 in the same row group. Each dual-purpose signal wire 19 short-circuits the dielectric elements 15 of each electrode unit 12 and the signal terminals 14-2 of each temperature sensor 14 in each column group, respectively, for receiving temperature detection signals or transmitting AC signals. The two grounding wires 18 of the electrode sheet 10H are respectively a first grounding wire 18-1 and a second grounding wire 18-2. In the two row groups of the electrode sheet 10H, the first row group includes electrode units 12-1 to 12-5, and the second row group includes electrode units 12-6 to 12-9. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-6 to 12-9 in the second row group. In short, each grounding wire 18 short-circuits and grounds the grounding ends 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.
[0099] The five dual-purpose signal lines 19 of the electrode sheet 10H include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-1 and electrode unit 12-6, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-2 and electrode unit 12-7, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-3 and electrode unit 12-8, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-9, and the signal end 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of the electrode unit 12-5 and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 in the same column group and the signal terminals 14 - 2 of the temperature sensors 14 in parallel and is used to connect to the adapter 20 .
[0100] The first grounding switch 25-1 and the second grounding switch 25-2 of the adapter 20 are electrically connected to the first grounding line 18-1 and the second grounding line 18-2 of the electrode sheet 10H through the first connector 40H, and the third grounding switch 25-3 and the fourth grounding switch 25-4 are in an idle disconnected state. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 of the adapter 20 are electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 through the first connector 40H.
[0101] The working mode of the tumor electric field treatment system formed by the electrode sheet 10H, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switching switches 26 are turned on and the collection terminals 1 are turned off, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 are connected to the AC signal. When the collection terminals 1 of all bidirectional switching switches 26 are turned on and the input terminals 2 are turned off, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of the row groups can be obtained in turn by turning on the grounding switches 25 in sequence. Among them, no operation is required for the grounding switches 25 in the idle disconnected state.
[0102] refer to Fig.17 As shown, the electrode sheet 10J of the tenth embodiment is also provided with 9 electrode units 12. In terms of electrical connection, the flexible circuit board 11J of the electrode sheet 10J arranges the 9 electrode units 12 into three rows and three columns, and each row has 3 electrode units 12. The electrode sheet 10J includes 3 grounding wires 18 and 3 dual-purpose signal wires 19. Each grounding wire 18 is used to ground the grounding end 14-1 of the temperature sensor 14 of each electrode unit 12 in a corresponding row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in a corresponding column group and the signal end 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The 3 grounding wires 18 of the electrode sheet 10J are respectively the first grounding wire 18-1, the second grounding wire 18-2 and the third grounding wire 18-3. In the three row groups of the electrode sheet 10J, the first row group includes electrode units 12-1 to 12-3, the second row group includes electrode units 12-4 to 12-6, and the third row group includes electrode units 12-7 to 12-9. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-3 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-4 to 12-6 in the second row group, and the third grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-7 to 12-9 in the third row group. In short, each grounding wire 18 short-circuits the grounding ends 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.
[0103] The three dual-purpose signal lines 19 of the electrode sheet 10J include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, and a third dual-purpose signal line 19-3. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the three electrode units 12, namely, the electrode unit 12-1, the electrode unit 12-4, and the electrode unit 12-7, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the three electrode units 12, namely, the electrode unit 12-2, the electrode unit 12-5, and the electrode unit 12-8, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the three electrode units 12, namely, the electrode unit 12-3, the electrode unit 12-6, and the electrode unit 12-9, and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 in the same column group and the signal terminals 14 - 2 of the temperature sensors 14 in parallel and is used to connect to the adapter 20 .
[0104] The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 of the adapter 20 are electrically connected to the first grounding line 18-1, the second grounding line 18-2 and the third grounding line 18-3 through the first connector 40J, and the fourth grounding switch 25-4 is in an idle disconnected state. The first two-way switch 26-1, the second two-way switch 26-2 and the third two-way switch 26-3 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2 and the third dual-purpose signal line 19-3 through the first connector 40J, and the fourth two-way switch 26-4 and the fifth two-way switch 26-5 are both in an idle disconnected state.
[0105] The working mode of the tumor electric field treatment system formed by the electrode sheet 10J, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switching switches 26 are turned on and the collection terminals 1 are turned off, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 are connected to the AC signal. When the collection terminals 1 of all bidirectional switching switches 26 are turned on and the input terminals 2 are turned off, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of each row group are sequentially obtained by turning on each grounding switch 25 in sequence. Among them, no operation is required for the grounding switch 25 in the idle disconnected state and the bidirectional switching switch 26 in the idle disconnected state.
[0106] In the tumor electric field treatment system of the present application, the flexible circuit boards (11, 11A, 11B, 11C, 11D, 11E, 11F, 11G, 11H, 11J) of the electrode sheets (10, 10A, 10B, 10C, 10D, 10D', 10D", 10E, 10F, 10G, 10H, 10J) are electrically connected to divide the electrode units 12 into multiple rows and columns, and the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row are electrically connected to the same grounding wire 18, and the electrode units 12 in the same column are electrically connected to ... in the same column are electrically connected to the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row are electrically connected to the same grounding wire 18, and the electrode units in the same column are electrically connected to the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row are electrically connected to the same grounding wire 18, The dielectric elements 15 of each element 12 and the signal ends 14-2 of each temperature sensor 14 are short-circuited and electrically connected to the same dual-purpose signal line 19; the adapter 20 is provided with a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26, and each grounding line 18 of the electrode sheets (10, 10A, 10B, 10C, 10D, 10D', 10D", 10E, 10F, 10G, 10H, 10J) is electrically connected one by one to the corresponding grounding switch 25, and each dual-purpose signal line 19 is electrically connected one by one to the corresponding bidirectional switching switch 26. Among them, the number of grounding switches 25 is greater than or equal to the number of grounding wires 18, and the number of bidirectional switching switches 26 is greater than or equal to the number of dual-purpose signal lines 19. Therefore, the adapter 20 can adapt to a variety of electrode sheets (10, 10A, 10B, 10C, 10D, 10D', 10D", 10E, 10F, 10G, 10H, 10J), which has a grounding switch 25 in an idle disconnected state and / or a bidirectional switching switch 26 in an idle disconnected state.
[0107] In the previous embodiment, the number of grounding switches 25 corresponding to each electrode sheet 10 of the adapter 20 is fixed to 4, and the number of bidirectional switching switches 26 corresponding to each electrode sheet 10 is fixed to 5, which can be applicable to a variety of different electrode sheets 10, but in some usage situations, there will be idle disconnected grounding switches 25 and / or idle disconnected bidirectional switching switches 26, which will be more complicated in program control. Another way is to provide a specific adapter for the number of grounding wires 18 and the number of dual-purpose signal wires 19 of the electrode sheet to avoid the occurrence of idle disconnected grounding switches 25 and / or idle disconnected bidirectional switching switches 26, which facilitates program control. To this end, the present application also provides other embodiments of other electrode sheets and adapters, which will be described separately below.
[0108] refer to Fig.18As shown, the electrode sheet 10K of the eleventh embodiment is provided with 20 electrode units, and its flexible circuit board 11K arranges these 20 electrode units 12 into five rows and four columns in terms of electrical connection, and each row has 4 electrode units 12. The electrode sheet 10K includes 5 grounding wires 18 and 4 dual-purpose signal wires 19. Each grounding wire 18 is used to ground the grounding end 14-1 of the temperature sensor 14 of each electrode unit 12 in a corresponding row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in a corresponding column group and the signal end 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The 5 grounding wires 18 of the electrode sheet 10K include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, a fourth grounding wire 18-4, and a fifth grounding wire 18-5. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, the fourth row group includes electrode units 12-13 to 12-16, and the fifth row group includes electrode units 12-17 to 12-20. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-5 to 12-8 in the second row group; the third grounding wire 18-3 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-9 to 12-12 in the third row group; the fourth grounding wire 18-4 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-13 to 12-16 in the fourth row group; the fifth grounding wire 18-5 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-17 to 12-20 in the fourth row group. In short, each ground line 18 short-circuits the ground terminals 14 - 1 of the temperature sensors 14 of all the electrode units 12 in each row group and connects them to ground.
[0109] The four dual-purpose signal lines 19 of the electrode sheet 10K include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the five electrode units 12, namely, the electrode unit 12-1, the electrode unit 12-5, the electrode unit 12-9, the electrode unit 12-13, and the electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the five electrode units 12, namely, the electrode unit 12-2, the electrode unit 12-6, the electrode unit 12-10, the electrode unit 12-14, and the electrode unit 12-18, and the signal end 14-2 of the temperature sensor 14; One end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the five electrode units 12, namely, electrode unit 12-3, electrode unit 12-7, electrode unit 12-11, electrode unit 12-15 and electrode unit 12-19, and the signal end 14-2 of the temperature sensor 14 of each electrode unit; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the five electrode units 12, namely, electrode unit 12-4, electrode unit 12-8, electrode unit 12-12, electrode unit 12-16 and electrode unit 12-20, and the signal end 14-2 of the temperature sensor 14 of each electrode unit 12. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 and the signal end 14-2 of the temperature sensor 14 of each electrode unit 12 in a corresponding column group in parallel and is used to connect to the adapter 20.
[0110] refer to Fig.18 The present application provides an adapter 20K of the second embodiment, which can be adapted to the electrode sheet 10K of the eleventh embodiment, and combined with Fig. 20As shown, the adapter 20K also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of pressure resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23, multiple groups of bidirectional switches 26 connected to the multiple groups of analog-to-digital converters 23, a first communication unit 27, an AC signal line 28 connected to each group of bidirectional switches 26, and a first power module 29 connected to the first communication unit 27, the first controller 22 and the multiple groups of analog-to-digital converters 23. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20K. The adapter 20K also includes multiple circuit lines (not numbered). The difference between the adapter 20 and the first embodiment is that each set of grounding switches 25 of the adapter 20K is increased by a fifth grounding switch 25-5, each set of bidirectional switching switches 26 is reduced by a fifth bidirectional switching switch 26-5, and the detection channel E corresponding to the fifth bidirectional switching switch 26-5 in each set of analog-to-digital converters 23 is reduced, and the voltage-dividing resistor corresponding to the fifth bidirectional switching switch 26-5 in each set of voltage-dividing resistors 24 is reduced. For other specific structures and working principles of the adapter 20K, please refer to the specific description of the adapter 20, which will not be repeated here.
[0111] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, the fourth grounding switch 25-4 and the fifth grounding switch 25-5 of the adapter 20K are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3, the fourth grounding line 18-4 and the fifth grounding line 18-5 of the electrode sheet 10K through the first connector 40K. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3 and the fourth two-way switch 26-4 of the adapter 20K are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3 and the fourth two-purpose signal line 19-4 of the electrode sheet 10K through the first connector 40K. The working mode of the tumor electric field therapy system formed by the electrode sheet 10K, the adapter 20K and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of the row groups can be obtained in turn by turning on the grounding switches 25 in turn.
[0112] refer to Fig.19As shown, the electrode sheet 10L of the twelfth embodiment is provided with 19 electrode units 12, and the flexible circuit board 11L arranges the 19 electrode units 12 into four rows and five columns in terms of electrical connection, wherein each of the four rows has four electrode units 12, and the remaining row has three electrode units 12. The electrode sheet 10L includes five grounding wires 18 and four dual-purpose signal wires 19, each of which is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12 in a corresponding row group, and each dual-purpose signal wire 19 is respectively short-circuited with the dielectric element 15 of each electrode unit 12 in a corresponding column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The five grounding wires 18 of the electrode sheet 10L include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, a fourth grounding wire 18-4 and a fifth grounding wire 18-5. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, the fourth row group includes electrode units 12-13 to 12-16, and the fifth row group includes electrode units 12-17 to 12-19. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-5 to 12-8 in the second row group; the third grounding wire 18-3 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-9 to 12-12 in the third row group; the fourth grounding wire 18-4 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-13 to 12-16 in the fourth row group; and the fifth grounding wire 18-5 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-17 to 12-19 in the fifth row group. In short, each ground line 18 short-circuits the ground terminals 14 - 1 of the temperature sensors 14 of all the electrode units 12 in each row group and connects them to ground.
[0113] The four dual-purpose signal lines 19 of the electrode sheet 10L include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the five electrode units 12, namely, the electrode unit 12-1, the electrode unit 12-5, the electrode unit 12-9, the electrode unit 12-13, and the electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the five electrode units 12, namely, the electrode unit 12-2, the electrode unit 12-6, the electrode unit 12-10, the electrode unit 12-14, and the electrode unit 12-18, and the signal end 14-2 of the temperature sensor 14 14-2; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the five electrode units 12, namely, electrode unit 12-3, electrode unit 12-7, electrode unit 12-11, electrode unit 12-15 and electrode unit 12-19, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-4, electrode unit 12-8, electrode unit 12-12 and electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 and the signal end 14-2 of the temperature sensor 14 in parallel and connects them to the adapter 20K.
[0114] refer to Fig.19The adapter 20K of the second embodiment can also be adapted to the electrode sheet 10L of the twelfth embodiment. The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, the fourth grounding switch 25-4 and the fifth grounding switch 25-5 of the adapter 20K are respectively electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, the fourth grounding wire 18-4 and the fifth grounding wire 18-5 of the electrode sheet 10L through the first connector 40L. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3 and the fourth two-way switch 26-4 of the adapter 20K are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3 and the fourth two-purpose signal line 19-4 of the electrode sheet 10L through the first connector 40L. The working mode of the tumor electric field therapy system formed by the electrode sheet 10L, the adapter 20K and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each of the grounding switches 25 in turn.
[0115] refer to Fig.21As shown, the electrode sheet 10M of the thirteenth embodiment is provided with 18 electrode units 12. In terms of electrical connection, the flexible circuit board 11M arranges the 18 electrode units 12 into three rows and six columns, and each row has 6 electrode units 12. The electrode sheet 10M includes three grounding wires 18 and six dual-purpose signal wires 19. Each grounding wire 18 is used to ground the grounding end 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 and the signal end 14-2 of each temperature sensor 14 in the same column group, respectively, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode sheet 10M include a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. The first row group includes electrode units 12-1 to 12-6, the second row group includes electrode units 12-7 to 12-12, and the third row group includes electrode units 12-13 to 12-18. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-6 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-7 to 12-12 in the second row group; and the third grounding wire 18-3 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-13 to 12-18 in the third row group. In short, each ground line 18 short-circuits the ground terminals 14 - 1 of the temperature sensors 14 of all the electrode units 12 in each row group and connects them to ground.
[0116] The six dual-purpose signal lines 19 of the electrode sheet 10M include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, a fifth dual-purpose signal line 19-5 and a sixth dual-purpose signal line 19-6. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-1, the electrode unit 12-7 and the electrode unit 12-13, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-2, the electrode unit 12-8 and the electrode unit 12-14, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-3, the electrode unit 12-9 and the electrode unit 12-15, and the signal end 14-2 of the temperature sensor 14 -2; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12, electrode unit 12-4, electrode unit 12-10, and electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the three electrode units 12, electrode unit 12-5, electrode unit 12-11, and electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14; one end of the sixth dual-purpose signal line 19-6 is connected to the dielectric elements 15 of the three electrode units 12, electrode unit 12-12, and electrode unit 12-18, and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 and the signal end 14-2 of the temperature sensor 14 in parallel in the corresponding same column group and is used to connect to the adapter 20M.
[0117] Combination Fig.23As shown, the electrode sheet 10M of the thirteenth embodiment is adapted to the adapter 20M of the third embodiment, and the adapter 20M also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of piezoelectric resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23, a first communication unit 27, an AC signal line 28 connected to each group of bidirectional switching switches 26, and a first power module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20M. The adapter 20M also includes multiple circuit lines (unnumbered). The difference between the adapter 20 and the aforementioned adapter 20 is that: each group of grounding switches 25 of the adapter 20M reduces the setting of a fourth grounding switch 25-4, each group of two-way switching switches 26 increases the setting of a sixth two-way switching switch 26-6, and increases the setting of a detection channel F corresponding to the sixth two-way switching switch 26-6 in each group of analog-to-digital converters 23 and increases the setting of a voltage-dividing resistor corresponding to the sixth two-way switching switch 26-6 in each group of voltage-dividing resistors 24. For other specific structures and working principles of the adapter 20M, please refer to the relevant specific description of the aforementioned adapter 20, which will not be repeated here.
[0118] The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 of the adapter 20M are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2 and the third grounding line 18-3 of the electrode sheet 10M through the first connector 40M. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4, the fifth two-way switch 26-5 and the sixth two-way switch 26-6 on the adapter 20M are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4, the fifth two-purpose signal line 19-5 and the sixth two-purpose signal line 19-6 of the electrode sheet 10M through the first connector 40M. The working mode of the tumor electric field treatment system formed by the electrode sheet 10M, the adapter 20M and the electric field generator 30 is the same as that of the previous tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each grounding switch 25 in turn.
[0119] refer to Fig. 22 As shown, the electrode sheet 10N of the fourteenth embodiment is provided with 17 electrode units 12. In terms of electrical connection, the flexible circuit board 11N arranges the 17 electrode units 12 into three rows and six columns, wherein each of the two rows has six electrode units 12, and the remaining row has five electrode units 12. The electrode sheet 10N includes three grounding wires 18 and six dual-purpose signal wires 19. Each grounding wire 18 is used to ground the grounding end 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in the same column group and the signal end 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode sheet 10N include a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. The first row group includes electrode units 12-1 to 12-6, the second row group includes electrode units 12-7 to 12-12, and the third row group includes electrode units 12-13 to 12-17. Specifically, the first grounding wire 18-1 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-6 in the first row group; the second grounding wire 18-2 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-7 to 12-12 in the second row group, and the third grounding wire 18-3 is used to ground the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-13 to 12-17 in the third row group. In short, each grounding wire 18 short-circuits the grounding ends 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.
[0120] The six dual-purpose signal lines 19 of the electrode sheet 10N include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, a fifth dual-purpose signal line 19-5 and a sixth dual-purpose signal line 19-6. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-1, the electrode unit 12-7 and the electrode unit 12-13, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-2, the electrode unit 12-8 and the electrode unit 12-14, and the signal end 14-2 of the temperature sensor 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-3, the electrode unit 12-9 and the electrode unit 12-15, and the signal end 14-2 of the temperature sensor 14 One end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12, electrode unit 12-4, electrode unit 12-10, and electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the three electrode units 12, electrode unit 12-5, electrode unit 12-11, and electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14; one end of the sixth dual-purpose signal line 19-6 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-6 and electrode unit 12-12, and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 of the electrode units 12 and the signal end 14-2 of the temperature sensor 14 in parallel and is used to connect to the adapter 20M.
[0121] refer to Fig. 22The adapter 20M of the third embodiment can also be adapted to the electrode sheet 10N of the fourteenth embodiment. The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 of the adapter 20M are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2 and the third grounding line 18-3 of the electrode sheet 10N through the first connector 40N. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4, the fifth two-way switch 26-5 and the sixth two-way switch 26-6 on the adapter 20M are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4, the fifth two-purpose signal line 19-5 and the sixth two-purpose signal line 19-6 of the electrode sheet 10N through the first connector 40N. The working mode of the tumor electric field therapy system formed by the electrode sheet 10N, the adapter 20M and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each of the grounding switches 25.
[0122] refer to Fig.24 and Fig.26 As shown, an adapter 20B of the fourth embodiment is provided for the electrode sheet 10D of the fifth embodiment. The adapter 20B also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of piezoelectric resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23, a first communication unit 27, an AC signal line 28 connected to each group of bidirectional switching switches 26 in a one-to-one correspondence, and a first power module 29 connected to the first communication unit 27, the first controller 22 and the multiple groups of analog-to-digital converters 23 at the same time, and the first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20B. The adapter 20B also includes multiple circuit lines (unnumbered). The difference between it and the aforementioned adapter 20 is that each group of grounding switches 25 of the adapter 20B reduces the setting of a fourth grounding switch 25-4. For other specific structures and working principles of the adapter 20B, please refer to the specific description of the adapter 20 mentioned above, which will not be repeated here.
[0123] The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 on the adapter 20B are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2 and the third grounding line 18-3 of the electrode sheet 10D through the first connector 40D'. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 on the adapter 20B are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 of the electrode sheet 10D through the first connector 40D'. The working mode of the tumor electric field therapy system formed by the electrode sheet 10D, the adapter 20B and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of the row groups can be obtained in turn by turning on the grounding switches 25 in turn.
[0124] refer to Fig.25 As shown, the adapter 20B of the fourth embodiment can also be adapted to the electrode sheet 10E of the aforementioned sixth embodiment, and the first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 on the adapter 20B are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2 and the third grounding line 18-3 of the electrode sheet 10E through the first connector 40E'. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 on the adapter 20B are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 of the electrode sheet 10E through the first connector 40E'. The working mode of the tumor electric field therapy system formed by the electrode sheet 10E, the adapter 20B and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of the row groups can be obtained in turn by turning on the grounding switches 25 in turn.
[0125] refer to Fig. 27 and Fig.29 As shown, an adapter 20C of the fifth embodiment is provided for the electrode sheet 10F of the seventh embodiment. The adapter 20C also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of piezoelectric resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23, a first communication unit 27, an AC signal line 28 connected to each group of bidirectional switching switches 26, and a first power supply module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23. The first power supply module 29 provides a DC power supply VCC for each electronic component of the adapter 20C. The adapter 20C also includes multiple circuit lines (unnumbered). The difference between the adapter 20 and the aforementioned adapter 20 is that each set of two-way switches 26 of the adapter 20C reduces the setting of a fifth two-way switch 26-5, reduces the setting of the detection channel E corresponding to the fifth two-way switch 26-5 in each set of analog-to-digital converters 23, and reduces the setting of the voltage-dividing resistor corresponding to the fifth two-way switch 26-5 in each set of voltage-dividing resistors 24. For other specific structures and working principles of the adapter 20C, please refer to the relevant specific description of the aforementioned adapter 20, which will not be repeated here.
[0126] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 of the adapter 20C are respectively electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3 and the fourth grounding line 18-4 of the electrode sheet 10F of the third embodiment through the first connector 40F'. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3 and the fourth two-way switch 26-4 on the adapter 20C are respectively electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3 and the fourth two-purpose signal line 19-4 through the first connector 40F'. The working mode of the tumor electric field therapy system formed by the electrode sheet 10F, the adapter 20C and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each of the grounding switches 25.
[0127] refer to Fig.28 As shown, the adapter 20C of the fifth embodiment can be adapted to the electrode sheet 10G of the aforementioned eighth embodiment. The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 on the adapter 20C are electrically connected one-to-one with the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3 and the fourth grounding line 18-4 of the electrode sheet 10G through the first connector 40G'. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3 and the fourth bidirectional switching switch 26-4 on the adapter 20C are electrically connected one-to-one with the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3 and the fourth dual-purpose signal line 19-4 through the first connector 40G'. Reference Fig.29 The working mode of the tumor electric field therapy system formed by the electrode sheet 10G, the adapter 20C and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each grounding switch 25 in turn.
[0128] refer to Fig.30 and Fig.31 As shown, an adapter 20D of the sixth embodiment is provided for the electrode sheet 10H of the ninth embodiment. The adapter 20D also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of piezoelectric resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23, a first communication unit 27, an AC signal line 28 connected to each group of bidirectional switching switches 26 corresponding to each other, and a first power module 29 connected to the first communication unit 27, the first controller 22 and the multiple groups of analog-to-digital converters 23 at the same time. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20D. The adapter 20D also includes multiple circuit lines (not numbered). The difference between it and the aforementioned adapter 20 is that each group of grounding switches 25 of the adapter 20D reduces the setting of a fourth grounding switch 25-4 and a third grounding switch 25-3. For other specific structures and working principles of the adapter 20D, please refer to the specific description of the adapter 20 mentioned above, which will not be repeated here.
[0129] The first grounding switch 25-1 and the second grounding switch 25-2 on the adapter 20D are electrically connected to the first grounding line 18-1 and the second grounding line 18-2 of the electrode sheet 10H through the first connector 40H'. The first two-way switch 26-1, the second two-way switch 26-2, the third two-way switch 26-3, the fourth two-way switch 26-4 and the fifth two-way switch 26-5 on the adapter 20D are electrically connected to the first two-purpose signal line 19-1, the second two-purpose signal line 19-2, the third two-purpose signal line 19-3, the fourth two-purpose signal line 19-4 and the fifth two-purpose signal line 19-5 through the first connector 40H'. Fig.31 The working mode of the tumor electric field therapy system formed by the electrode sheet 10H, the adapter 20D and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each grounding switch 25 in turn.
[0130] refer to Fig.32As shown, an adapter 20E of the seventh embodiment is provided for the electrode sheet 10J of the tenth embodiment. The adapter 20E also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of piezoelectric resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23, a first communication unit 27, an AC signal line 28 connected to each group of bidirectional switching switches 26, and a first power supply module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23. The first power supply module 29 provides a DC power supply VCC for each electronic component of the adapter 20E. The adapter 20E also includes multiple circuit lines (unnumbered). The difference between the adapter 20 and the aforementioned adapter 20 is that each set of grounding switches 25 of the adapter 20E reduces the setting of a fourth grounding switch 25-4, each set of two-way switching switches 26 reduces the setting of a fifth two-way switching switch 26-5 and a fourth two-way switching switch 26-4, and reduces the setting of detection channels E and detection channels D corresponding to the fifth two-way switching switch 26-5 and the fourth two-way switching switch 26-4 in each set of analog-to-digital converters 23, and reduces the setting of voltage-dividing resistors corresponding to the fifth two-way switching switch 26-5 and the fourth two-way switching switch 26-4 in each set of voltage-dividing resistors 24. For other specific structures and working principles of the adapter 20E, please refer to the relevant specific description of the aforementioned adapter 20, which will not be repeated here.
[0131] The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 on the adapter 20E are electrically connected to the first grounding line 18-1, the second grounding line 18-2 and the third grounding line 18-3 through the first connector 40J'. The first two-way switch 26-1, the second two-way switch 26-2 and the third two-way switch 26-3 on the adapter 20E are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2 and the third dual-purpose signal line 19-3 through the first connector 40J'. Fig.33 The working mode of the tumor electric field therapy system formed by the electrode sheet 10J, the adapter 20E and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are turned on and the collection terminals 1 are disconnected, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the collection terminals 1 of all the bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each grounding switch 25 in turn.
[0132] The present application also provides some temperature detection methods and AC signal application control methods, which are described below using the electrode sheet 10 as an example.
[0133] The present application embodiment provides an electrode sheet temperature detection method, which is applied to the above-mentioned electrode sheet 10 or tumor electric field treatment system 100. Fig.34 As shown, it includes the following steps: Step 210: Control each bidirectional switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to disconnect the AC signal applied to the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 and connect the DC signal applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10; Step 220 : Turn on the grounding switches 25 electrically connected to the grounding terminals 14 - 1 of the temperature sensors 14 of the electrode units 12 of the electrode sheet 10 in sequence to obtain temperature detection signals from the temperature sensors 14 of the electrode units 12 of the electrode sheet 10 .
[0134] Step 210 is specifically as follows: controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch from one end electrically connected to the AC signal to one end electrically connected to the DC signal, that is, controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from its input end 2 to its collection end 1; or controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 from the on state to the off state, and at the same time switching the signal end 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 from the off state to the on state.
[0135] The electrode sheet temperature detection method of the present application can quickly and accurately obtain the temperatures of all electrode units of the electrode sheet; and based on the temperature detection signals of all the temperature sensors of the electrode sheet, it can be judged whether the temperature sensors of the electrode sheet are faulty, whether there is an abnormality, whether the electrode sheet is qualified, and whether it needs to be replaced; it is also possible to judge whether each electrode unit of the electrode sheet is over-temperature based on the temperature detection signals of all the temperature sensors of the electrode sheet when each temperature sensor of the electrode sheet is normal, and then control the alternating current signal applied to the electrode sheet or to each electrode unit of the electrode sheet; it is also possible to identify the type of electrode sheet when there is no abnormality in the temperature detection signals of each temperature sensor of the electrode sheet.
[0136] Ginseng Fig.35 As shown, the embodiment of the present application also provides a method for controlling application of an alternating current signal for tumor electric field therapy, which includes the above steps 210 and 220, and after step 220, further includes: Step 260 : When it is determined that the electrode sheet 10 does not need to be replaced, the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 is controlled or adjusted according to the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 .
[0137] Controlling or adjusting the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 in step 260 also includes: Step 261: When the temperature detection signals of the electrode units 12 of the electrode sheet 10 obtained do not exceed the preset temperature threshold, continue to apply an alternating current signal to the electrode units 12 of the electrode sheet 10; or Step 262 : when there is a temperature detection signal exceeding a preset temperature threshold among the temperature detection signals of all the electrode units 12 of the electrode sheet 10 , stop applying the alternating current signal to the electrode units 12 of the electrode sheet 10 .
[0138] Stopping the application of the AC signal to the electrode unit 12 of the electrode sheet 10 described in step 262 includes stopping applying the AC signal to all electrode units 12 of the electrode sheet 10, stopping applying the AC signal to the electrode unit 12 in the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold, and stopping applying the AC signal to all electrode units 12 in the column where the electrode unit 12 in the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold is located.
[0139] When the application of the AC signal to the electrode unit 12 in the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold is stopped, the AC signal continues to be applied to the electrode unit 12 in the electrode sheet 10 whose temperature detection signal does not exceed the preset temperature threshold.
[0140] When the application of the AC signal to all the electrode units 12 in the column where the electrode unit 12 whose temperature detection signal exceeds the preset temperature threshold in the electrode sheet 10 is located is stopped, the AC signal continues to be applied to all the electrode units 12 in the electrode sheet 10 where the temperature detection signal does not exceed the preset temperature threshold and which are in different columns from the electrode unit 12 whose temperature detection signal exceeds the preset temperature threshold.
[0141] The process of continuing to apply the alternating current signal to the electrode sheet 10 in step 261 is specifically as follows: Step 263: When the temperature detection signal is much lower than the preset temperature threshold, the AC signal is continuously applied to each electrode unit 12 of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 or the AC signal is continuously applied to each electrode unit 12 of the electrode sheet 10 in a manner of keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 unchanged; or Step 264: When the temperature detection signal approaches a preset temperature threshold, continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 unchanged, or continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner that reduces the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10.
[0142] Ginseng Fig.36 As shown, the present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned electrode sheet 10, and the method includes: Step 310: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 to apply an AC signal to each electrode unit 12 of the electrode sheet 10 and executing step 320; Step 320: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to collect the temperature detection signals of the electrode units of the electrode sheet 10 in a row and executing step 330; Step 330: Determine the combined control mode of the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 according to the collected temperature detection signal and execute step 340; Step 340 : Control the working state of each electrode unit 12 of the electrode sheet 10 according to the determined combined control mode of the grounding switch 25 and the bidirectional switch 26 .
[0143] The working states of the electrode units 12 of the electrode sheet 10 described in step 340 include: stopping applying the AC signal and continuing to collect the temperature detection signal and stopping collecting the temperature detection signal and continuing to apply the AC signal. Continuing to apply the AC signal includes continuing to apply the AC signal in a manner of increasing the voltage or current amplitude of the currently applied AC signal, continuing to apply the AC signal in a manner of keeping the voltage or current amplitude of the currently applied AC signal unchanged, and continuing to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal.
[0144] The working state of each electrode unit 12 of the electrode sheet 10 is determined by the temperature detection signal collected by the electrode unit 12. Each electrode unit 12 of the electrode sheet 10 is divided into different areas, and each electrode unit 12 in each area can be cyclically switched between applying an AC signal and collecting a temperature detection signal through the combination control of a grounding switch 25 and a bidirectional switch 26.
[0145] The present application embodiment provides another electrode temperature detection method for the tumor electric field treatment system 100, please refer to Fig.37 As shown, the temperature detection method includes: Step 510: disconnect the input of the alternating current signal of the electrode sheet 10, perform combination control on the multiple grounding switches 25 and the multiple bidirectional switching switches 26, and obtain the temperature detection signal of the temperature sensor 14 of the electrode sheet 10 corresponding to each combination in all the combinations; Step 520: sampling and converting the temperature detection signal detected by each temperature sensor 14 in the electrode sheet 10 to obtain a digital temperature signal; Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field therapy system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 12 according to the digital temperature signal.
[0146] In step 510, “combining and controlling the plurality of grounding switches 25 and the plurality of bidirectional switching switches 26” specifically includes: Step 511: placing all the bidirectional switches 26 at the acquisition end 1 to conduct the electrical connection between the signal end 14 - 2 of each temperature sensor 14 of all electrode units 12 and the corresponding analog-to-digital converter 23 ; Step 512: Sequentially and individually close one of the plurality of grounding switches 25 in a time-sharing manner to collect the temperature detection signals detected by the temperature sensors 14 of the electrode units 12 in the corresponding row group row by row.
[0147] In step 512, sequentially and individually closing one of the plurality of grounding switches 25 in a time-sharing manner can turn on the detection channel of the analog-to-digital converter 23 electrically connected to each temperature sensor 14 in the row group corresponding to the closed grounding switch 25 .
[0148] Thus, the temperature detection signals of the corresponding temperature sensors 14 in each row group can be obtained in turn, and then after being processed by the adapter 20 or the electric field generator 30, the corresponding temperatures of all the electrode units 12 on the electrode sheet 10 can be obtained; thereby making the temperature detection of the patient's body surface more comprehensive and accurate.
[0149] For the tumor electric field therapy system 100 of the embodiment of the present application, the temperature of a single electrode unit 12 can also be detected as needed. The specific process of the method for temperature detection of a certain electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the AC signal, place the bidirectional switch 26 corresponding to the column group where the electrode unit 12 that needs to be individually measured is located at the acquisition end 1, and place the remaining bidirectional switches 26 at the input end 2; at the same time, turn on and ground the grounding switch 25 corresponding to the row group where the electrode unit 12 that needs to be individually measured is located, and disconnect all the remaining grounding switches 25. In this way, the temperature detection signal of the temperature sensor 14 in the electrode unit 12 that needs to be individually measured can be sampled to obtain the temperature of the electrode unit 12. For example, the electrode unit 12 that needs to be individually measured is the electrode unit 12-1. At this time, the corresponding AC signal switch 35 of the electric field generator 30 is disconnected, and the first two-way switch 26-1 corresponding to the electrode unit 12-1 is placed at the collection end 1, and the remaining two-way switches (the second two-way switch 26-2, the second two-way switch 26-3, the third two-way switch 26-3 and the fourth two-way switch 26-4) are all placed at the input end 2; at the same time, the first grounding switch 25-1 corresponding to the electrode unit 12-1 is closed and grounded, and the remaining grounding switches (the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4) are all disconnected. In this way, the temperature of the electrode unit 12-1 can be detected.
[0150] The present application also provides another method for applying an alternating current signal for tumor electric field therapy, which is applied to the above-mentioned tumor electric field therapy system 100. Please refer to Fig.38 As shown, the AC signal application method includes: Step 610: determining the area of the electrode unit 12 in the electrode sheet 10 where the alternating current signal needs to be applied; Step 611: Combining and controlling a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26 electrically connected to the electrode sheet 10 to apply an alternating current signal.
[0151] In step 611, “combining and controlling a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26 electrically connected to the electrode sheet 10” is specifically as follows: Step 612: disconnect all grounding switches 25 electrically connected to the electrode sheet 10; Step 613: determining the column group where the electrode units 12 to which the AC signal needs to be applied are located according to the area where the electrode units 12 to which the AC signal needs to be applied are located; Step 614: determining the bidirectional switches 26 electrically connected to the electrode units 12 in the column groups according to the column groups where the electrode units 12 to which the AC signal needs to be applied are located; In step 610 , every four adjacent electrode units 12 in the electrode sheet 10 are divided into a region. The four electrode units 12 in each region correspond to a column group and are connected to a dual-purpose signal line 19 corresponding to the same bidirectional switch 26 .
[0152] Step 615: Control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which an AC signal needs to be applied so that the electrode unit 12 to which an AC signal needs to be applied is electrically connected to the AC signal line 28 to apply the AC signal; at the same time, control the remaining bidirectional switching switches 26 so that the electrical connection between each electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28 is disconnected to stop applying the AC signal.
[0153] In step 615, "the electrode units to which an AC signal needs to be applied are electrically connected to the AC signal line 28 to apply the AC signal and the electrode units 12 in the area where the AC signal does not need to be applied are electrically disconnected from the AC signal line 28 to stop applying the AC signal" is achieved by placing the bidirectional switching switch 26 electrically connected to the electrode units 12 in the column group corresponding to the area to which the AC signal is to be applied in the electrode sheet 10 at its input end 2, and placing all the bidirectional switching switches 26 electrically connected to the electrode units 12 in the remaining column groups at the collection end 1.
[0154] The first controller 22 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.
[0155] The present application also provides an AC signal application method based on a temperature detection signal, which is used in the above-mentioned tumor electric field treatment system 100. Fig.39 As shown, the application method includes: Step 710: Start the tumor therapeutic field system 100; Step 711: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 to apply an AC signal to each electrode unit 12 of the electrode sheet 10; Step 712: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10; Step 713: Determine whether there is an electrode unit 12 whose temperature exceeds the first preset temperature t1, and execute step 714 when there is no electrode unit 12 whose temperature exceeds the first preset temperature t1; and execute step 715 when there is an electrode unit 12 whose temperature exceeds the first preset temperature t1; Step 714: Continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the currently applied AC signal and return to step 712; Step 715: Determine whether there is an electrode unit 12 whose temperature exceeds the second preset temperature t2; when there is no electrode unit 12 whose temperature exceeds the second preset temperature t2, execute step 716; when there is an electrode unit 12 whose temperature exceeds the second preset temperature t2, execute step 717; Step 716: Continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the currently applied AC signal unchanged and return to step 712; Step 717: Determine whether there is an electrode unit 12 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 12 whose temperature exceeds the preset temperature threshold t0, execute step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 719; Step 718: Continue to apply the AC signal to all electrode units 12 of the electrode sheet 10 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 712; Step 719: Determine the number of over-temperature regions and execute step 720, wherein the over-temperature region is a region containing electrode units whose temperature exceeds a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperature of all electrode units does not exceed the preset temperature threshold t0; Step 720: Determine whether the number of over-temperature areas exceeds a preset number threshold, and execute step 721 when the number of over-temperature areas exceeds the preset number threshold; and execute step 724 when the number of over-temperature areas does not exceed the preset number threshold. Step 721: stop applying the AC signal to each electrode unit 12 of the electrode sheet 10 and execute step 722; Step 722: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10 and executing step 723; Step 723: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, and when the electrode sheet 10 does not have an electrode unit 12 with a temperature exceeding the first preset temperature t1, return to step 711; when the electrode sheet 10 has an electrode unit 12 with a temperature exceeding the first preset temperature t1, return to step 722; Step 724: distinguishing an over-temperature area from a non-over-temperature area according to whether there is an electrode unit 12 whose temperature exceeds a preset temperature threshold t0, and executing step 725 when the area is an over-temperature area, and executing step 726 when the area is a non-over-temperature area; Step 725: stop applying the AC signal to each electrode unit 12 in the over-temperature area and execute step 731; Step 726: Determine whether the temperature of each electrode unit 12 in the non-over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 12 in the non-over-temperature area does not exceed the first preset temperature t1, execute step 727. When the temperature of each electrode unit 12 in the non-over-temperature area exceeds the first preset temperature t1, execute step 728. Step 727: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the currently applied AC signal and execute step 731; Step 728: Determine whether the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the second preset temperature t2. When the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 729. When the temperature of each electrode unit 12 in the non-overtemperature area exceeds the second preset temperature t2, execute step 730. Step 729: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area of the electrode sheet 10 in a manner that the voltage or current amplitude of the currently applied AC signal remains unchanged and execute step 731; Step 730: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area of the electrode sheet 10 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and execute step 731; Step 731: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to reacquire the temperature of each electrode unit 12 of the electrode sheet 10 and selecting to execute step 732 or step 734, wherein the temperature of each electrode unit 12 of the electrode sheet 10 includes the temperature of each electrode unit 12 in the over-temperature area and the temperature of each electrode unit 12 in the non-over-temperature area; Step 732: Determine whether the temperature of each electrode unit 12 in the over-temperature area does not exceed the first preset temperature t1, and execute step 733 when the temperature of each electrode unit 12 in the over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 12 in the over-temperature area exceeds the first preset temperature t1, return to step 731; Step 733: re-determine the area as a non-overtemperature area and execute step 734; Step 734: Determine whether the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the first preset temperature t1. When the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the first preset temperature t1, execute step 735. When the temperatures of the electrode units 12 in the non-over-temperature area exceed the first preset temperature t1, execute step 736. Step 735: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 712; Step 736: Determine whether the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the second preset temperature t2. When the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the second preset temperature t2, execute step 737. When the temperatures of the electrode units 12 in the non-over-temperature area exceed the second preset temperature t2, execute step 738. Step 737: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area in a manner that the voltage or current amplitude of the currently applied AC signal remains unchanged and return to step 712; Step 738: Determine whether the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the preset temperature threshold t0. When the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the preset temperature threshold t0, execute step 739. When the temperatures of the electrode units 12 in the non-over-temperature area exceed the preset temperature threshold t0, return to step 719. Step 739 : Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 712 .
[0156] Among them, Fig.39 As shown, the process of combining and controlling the ground switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 in step 711 to apply an AC signal to each electrode unit 12 of the electrode sheet is specifically as follows: Disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to one end at which an AC signal is applied to each electrode unit 12; or disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to one end at which each electrode unit 12 is electrically connected to the AC signal line 28; or disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to their respective input ends 2.
[0157] The process of obtaining the temperature of each electrode unit 12 of the electrode sheet 10 in step 712, step 722, and step 731 is specifically as follows: The bidirectional switch 26 electrically connected to the electrode sheet 10 is controlled to switch from the end at which the alternating current signal is applied to each electrode unit 12 to the end at which the temperature of each electrode unit 12 is collected, and the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 is closed in sequence in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or the bidirectional switch 26 electrically connected to the electrode sheet 10 is controlled to switch from the input end 2 at which the alternating current signal is applied to each electrode unit 12 to the collection end 1, and the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 is closed in sequence in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or the bidirectional switch 26 electrically connected to the electrode sheet 10 is controlled to switch from the input end 2 at which the alternating current signal is applied to each electrode unit 12 to the collection end 1, and the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 is closed in sequence in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; 0, so that each electrode unit 12 of the electrode sheet 10 is electrically connected to the AC signal line 28 to switch to each electrode unit 12 being electrically connected to the corresponding analog-to-digital converter 23, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or the bidirectional switching switch 26 electrically connected to the electrode sheet 10 is controlled so that each electrode unit 12 of the electrode sheet 10 is switched from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode sheet 10.
[0158] The first preset temperature in step 713, step 723, step 726, step 732, and step 734 is 40°C-40.3°C, preferably 40.2°C. The second preset temperature in step 715, step 728, and step 736 is 40.4°C to 40.6°C, preferably 40.5°C; the preset temperature threshold in step 717 and step 738 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in step 720 is preferably 2.
[0159] The process of continuing to apply the AC signal in step 714, step 716, step 718, step 727, step 729, step 730, step 735, step 737, and step 739 is specifically as follows: Disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to conduct the AC signal transmission path electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, so as to continue to apply the AC signal to the electrode unit 12 to which the AC signal needs to be continuously applied; or disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to switch from their respective collection terminals 1 to their respective input terminals 2, so as to continue to apply the AC signal to the electrode unit 12 to which the AC signal needs to be continuously applied; or disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to switch from their respective collection terminals 1 to their respective input terminals 2, so as to continue to apply the AC signal to the electrode unit 12 to which the AC signal needs to be continuously applied. The input ends 2 of the bidirectional switching switches 26 electrically connected to the electrode unit 12 for applying the AC signal are electrically connected to the AC signal line 28 so that the AC signal continues to be applied to the electrode unit 12 to which the AC signal needs to be applied; or the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be applied is disconnected, and at the same time, the bidirectional switching switches 26 electrically connected to the electrode unit 12 to which the AC signal needs to be applied are controlled so that their respective input ends 2 are closed and the collection end 1 is disconnected so that the AC signal continues to be applied to the electrode unit 12 to which the AC signal needs to be applied; or the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be applied is disconnected, and at the same time, the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be applied is controlled so that the electrode unit 12 to which the AC signal needs to be applied switches from transmitting the temperature detection signal to applying the AC signal.
[0160] Increasing the voltage or current amplitude of the currently applied AC power signal in step 714, step 727, and step 735 is specifically to boost the voltage of the currently applied AC power signal in a manner of a DC voltage amplitude increment of 0.03 V per second.
[0161] Continuing to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal in step 718, step 730, and step 739 specifically means continuing to apply the AC signal in a manner of 5V less than the voltage amplitude of the currently applied AC signal and continuing for 3 minutes.
[0162] The process of stopping applying the alternating current signal to each electrode unit 12 of the electrode sheet 10 described in step 721 is specifically as follows: controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to disconnect the electrical connection between each electrode unit 12 of the electrode sheet 10 and the AC signal line 28; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the end at which each electrode unit 12 is applied with the alternating current signal to the end at which each electrode unit 12 performs temperature acquisition; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the input end 2 at which each electrode unit 12 is applied with the alternating current signal to the acquisition end 1; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the electrical connection between each electrode unit 12 and the AC signal line 28 to the electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch each electrode unit 12 of the electrode sheet 10 from transmitting the alternating current signal to transmitting the direct current signal or the temperature detection signal.
[0163] The process of stopping applying the AC signal to each electrode unit 12 in the over-temperature area described in step 725 is specifically: controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to disconnect the electrical connection between each electrode unit 12 in the over-temperature area and the AC signal line 28; or controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all ends from the end where the AC signal is applied to each electrode unit 12 in the over-temperature area to the end where the temperature of each electrode unit 12 in the over-temperature area is collected; or Control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all input ends 2 for applying alternating current signals to each electrode unit 12 in the over-temperature area to their collection ends 1; or control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch each electrode unit 12 in the over-temperature area from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch each electrode unit 12 in the over-temperature area from transmitting alternating current signals to transmitting direct current signals or temperature detection signals.
[0164] In the above application method, the tumor electric field treatment system 100 includes at least two pairs of electrode sheets 10 to alternately apply alternating electric fields with different directions, and each electrode sheet 10 can alternately switch between applying an alternating current signal and transmitting a temperature detection signal. The time periods for applying an alternating current signal and applying a direct current signal for temperature collection of the electrode unit 12 of the same electrode sheet 10 are staggered and do not overlap.
[0165] The first controller 22 or the electric field generator 30 in the adapter 20 of the tumor electric field treatment system 100 of the present embodiment of the present application is also provided with a third preset temperature t3, and the third preset temperature t3 is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The present embodiment of the present application also provides an AC signal control method based on a temperature detection signal, which is used in the above tumor electric field treatment system, Fig.40 As shown, the AC signal control method includes: Step 810: Start the tumor therapeutic field system 100; Step 811: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 to apply an AC signal to each electrode unit 12 of the electrode sheet 10; Step 812: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10; Step 813: Determine whether there is an electrode unit 12 whose temperature exceeds the first preset temperature t1, and execute step 814 when there is no electrode unit 12 whose temperature exceeds the first preset temperature t1; and execute step 815 when there is an electrode unit 12 whose temperature exceeds the first preset temperature t1; Step 814: Continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the currently applied AC signal and return to step 812; Step 815: Determine whether there is an electrode unit 12 whose temperature exceeds the second preset temperature t2; when there is no electrode unit 12 whose temperature exceeds the second preset temperature t2, execute step 816; when there is an electrode unit 12 whose temperature exceeds the second preset temperature t2, execute step 817; Step 816: Continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner that the voltage or current amplitude of the currently applied AC signal remains unchanged and return to step 812; Step 817: Determine whether there is an electrode unit 12 whose temperature exceeds the third preset temperature t3. If there is no electrode unit 12 whose temperature exceeds the third preset temperature t3, execute step 818; if there is an electrode unit whose temperature exceeds the third preset temperature t3, execute step 819; Step 818: Continue to apply the AC signal to all electrode units 12 of the electrode sheet 10 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 812; Step 819: Determine whether there is an electrode unit 12 whose temperature exceeds the preset temperature threshold t0, and execute step 820 when there is no electrode unit 12 whose temperature exceeds the preset temperature threshold t0; execute step 821 when there is an electrode unit whose temperature exceeds the preset temperature threshold t0; Step 820: Continue to apply the AC signal to all electrode units 12 of the electrode sheet 10 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 812; Step 821: Determine the number of over-temperature regions and execute step 822, wherein the over-temperature region is a region containing electrode units whose temperature exceeds a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperature of all electrode units does not exceed the preset temperature threshold t0; Step 822: Determine whether the number of over-temperature areas exceeds a preset number threshold, and execute step 823 when the number of over-temperature areas exceeds the preset number threshold; and execute step 826 when the number of over-temperature areas does not exceed the preset number threshold; Step 823: stop applying the AC signal to each electrode unit 12 of the electrode sheet 10 and execute step 824; Step 824: Combine and control the ground switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10 and execute step 825; Step 825: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. When the electrode sheet 10 does not have an electrode unit 12 with a temperature exceeding the first preset temperature t1, return to step 811. When the electrode sheet 10 has an electrode unit 12 with a temperature exceeding the first preset temperature t1, return to step 824. Step 826: Distinguish the over-temperature area and the non-over-temperature area according to whether there is an electrode unit 12 whose temperature exceeds the preset temperature threshold t0, and execute step 827 when the area is the over-temperature area, and execute step 828 when the area is the non-over-temperature area; Step 827: stop applying the AC signal to each electrode unit 12 in the over-temperature area and execute step 835; Step 828: Determine whether the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 829. When the temperature of each electrode unit 12 in the non-overtemperature area exceeds the first preset temperature t1, execute step 830. Step 829: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the currently applied AC signal and execute step 835; Step 830: Determine whether the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the second preset temperature t2. When the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 831. When the temperature of each electrode unit 12 in the non-overtemperature area exceeds the second preset temperature t2, execute step 832. Step 831: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area of the electrode sheet 10 in a manner that the voltage or current amplitude of the currently applied AC signal remains unchanged and execute step 835; Step 832: Determine whether there is an electrode unit 12 in the non-overtemperature area whose temperature exceeds the third preset temperature t3, and execute step 833 when the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the third preset temperature t3; and execute step 834 when there is a temperature exceeding the third preset temperature t3 among the temperatures of each electrode unit 12 in the non-overtemperature area; Step 833: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area of the electrode sheet 10 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and execute step 835; Step 834: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area of the electrode sheet 10 in a manner of further reducing the voltage or current amplitude of the currently applied AC signal and execute step 835; Step 835: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to reacquire the temperature of each electrode unit 12 of the electrode sheet 10 and selecting to execute step 836 or step 838, wherein the temperature of each electrode unit 12 of the electrode sheet 10 includes the temperature of each electrode unit 12 in the over-temperature area and the temperature of each electrode unit 12 in the non-over-temperature area; Step 836: Determine whether the temperature of each electrode unit 12 in the over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 12 in the over-temperature area does not exceed the first preset temperature t1, execute step 837. When the temperature of each electrode unit 12 in the over-temperature area exceeds the first preset temperature t1, return to step 835. Step 837: re-determine the area as a non-overtemperature area and execute step 838; Step 838: Determine whether the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the first preset temperature t1. When the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the first preset temperature t1, execute step 839. When the temperatures of the electrode units 12 in the non-over-temperature area exceed the first preset temperature t1, execute step 840. Step 839: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 812; Step 840: Determine whether the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the second preset temperature t2. When the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the second preset temperature t2, execute step 841. When the temperatures of the electrode units 12 in the non-over-temperature area exceed the second preset temperature t2, execute step 842. Step 841: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area in a manner that the voltage or current amplitude of the currently applied AC signal remains unchanged and return to step 812; Step 842: Determine whether the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the third preset temperature t3. When the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the third preset temperature t3, execute step 843. When the temperatures of the electrode units 12 in the non-over-temperature area exceed the third preset temperature t3, execute step 844. Step 843: Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 812; Step 844: Determine whether the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the preset temperature threshold t0. When the temperatures of the electrode units 12 in the non-over-temperature area do not exceed the preset temperature threshold t0, execute step 845. When the temperatures of the electrode units 12 in the non-over-temperature area exceed the preset temperature threshold t0, return to step 821. Step 845 : Continue to apply the AC signal to each electrode unit 12 in the non-overtemperature area in a manner of further reducing the voltage or current amplitude of the currently applied AC signal and return to step 812 .
[0166] The process of combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 in step 811 to apply an AC signal to each electrode unit 12 of the electrode sheet is specifically as follows: Disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to one end at which an AC signal is applied to each electrode unit 12; or disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to one end at which each electrode unit 12 is electrically connected to the AC signal line 28; or disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to their respective input ends 2.
[0167] The process of obtaining the temperature of each electrode unit 12 of the electrode sheet 10 in step 812, step 824, and step 835 is specifically as follows: The bidirectional switch 26 electrically connected to the electrode sheet 10 is controlled to switch from the end at which the alternating current signal is applied to each electrode unit 12 to the end at which the temperature of each electrode unit 12 is collected, and the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 is closed in sequence in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or the bidirectional switch 26 electrically connected to the electrode sheet 10 is controlled to switch from the input end 2 at which the alternating current signal is applied to each electrode unit 12 to the collection end 1, and the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 is closed in sequence in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or the bidirectional switch 26 electrically connected to the electrode sheet 10 is controlled to switch from the input end 2 at which the alternating current signal is applied to each electrode unit 12 to the collection end 1, and the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 is closed in sequence in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; 0, so that each electrode unit 12 of the electrode sheet 10 is electrically connected to the AC signal line 28 to switch to each electrode unit 12 being electrically connected to the corresponding analog-to-digital converter 23, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or the bidirectional switching switch 26 electrically connected to the electrode sheet 10 is controlled so that each electrode unit 12 of the electrode sheet 10 is switched from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode sheet 10.
[0168] The first preset temperature in step 813, step 825, step 828, step 836, and step 838 is 40°C-40.3°C, preferably 40.2°C. The second preset temperature in step 815, step 830, and step 840 is 40.4°C to 40.6°C, preferably 40.5°C; the third preset temperature in step 817, step 832, and step 842 is 40.7°C to 40.9°C, preferably 40.8°C; the preset temperature threshold in step 819 and step 844 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in step 822 is preferably 2.
[0169] The process of continuing to apply the AC signal described in step 814, step 816, step 818, step 820, step 829, step 831, step 833, step 834, step 839, step 841, step 843, and step 845 is specifically as follows: disconnecting the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and at the same time controlling the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to conduct the AC signal transmission path electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, so as to continue to apply the AC signal to the electrode unit 12 to which the AC signal needs to be continuously applied; or disconnecting the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and at the same time controlling the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to switch from their respective collection terminals 1 to their respective input terminals 2, so as to continue to apply the AC signal to the electrode unit 12 to which the AC signal needs to be continuously applied; Or disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied so that their respective input ends 2 are electrically connected to the AC signal line 28 so that the AC signal continues to be applied to the electrode unit 12 to which the AC signal needs to be continuously applied; or disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied so that their respective input ends 2 are closed and the collection end 1 is disconnected so that the AC signal continues to be applied to the electrode unit 12 to which the AC signal needs to be continuously applied; or disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied so that the electrode unit 12 to which the AC signal needs to be continuously applied switches from transmitting the temperature detection signal to applying the AC signal.
[0170] The method of increasing the voltage or current amplitude of the currently applied AC signal in step 814, step 829, and step 839 is to continue to apply the AC signal by boosting the currently applied AC signal with a DC voltage amplitude increment of 0.03V per second and then continue to apply the AC signal.
[0171] Continuing to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal as described in step 818, step 820, step 833, step 834, step 843 and step 845 specifically means continuing to apply the AC signal in a manner of 5V less than the voltage amplitude of the currently applied AC signal and continuing for 3 minutes.
[0172] The process of stopping applying the alternating current signal to each electrode unit 12 of the electrode sheet 10 described in step 823 is specifically as follows: controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to disconnect the electrical connection between each electrode unit 12 of the electrode sheet 10 and the AC signal line 28; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the end at which each electrode unit 12 is applied with the alternating current signal to the end at which each electrode unit 12 is subjected to temperature acquisition; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the input end 2 at which each electrode unit 12 is applied with the alternating current signal to the acquisition end 1; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the electrical connection between each electrode unit 12 and the AC signal line 28 to the electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch each electrode unit 12 of the electrode sheet 10 from transmitting the alternating current signal to transmitting the direct current signal or the temperature detection signal.
[0173] The process of stopping applying the AC signal to each electrode unit 12 in the over-temperature area described in step 827 is specifically: controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to disconnect the electrical connection between each electrode unit 12 in the over-temperature area and the AC signal line 28; or controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all ends from the end where the AC signal is applied to each electrode unit 12 in the over-temperature area to the end where the temperature of each electrode unit 12 in the over-temperature area is collected; or Control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all input ends 2 for applying alternating current signals to each electrode unit 12 in the over-temperature area to their collection ends 1; or control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch each electrode unit 12 in the over-temperature area from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch each electrode unit 12 in the over-temperature area from transmitting alternating current signals to transmitting direct current signals or temperature detection signals.
[0174] When the tumor electric field therapy system 100 is in a standby state before starting work, no AC signal is applied to the electrode unit 12, and the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the bidirectional switch 26 to switch to the acquisition end 1, and the grounding switches 25 are turned on in turn, and the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to each row of electrode units 12 in turn.
[0175] When the first grounding switch 25 - 1 is turned on, the other grounding switches 25 are turned off, and the bidirectional switching switches 26 are all placed at the collection end 1 , the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12 ; When the second grounding switch 25 - 2 is turned on, the other grounding switches 25 are all turned off, and the bidirectional switching switches 26 are all placed at the collection end 1 , the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12 ; When the third grounding switch 25 - 3 is turned on, the other grounding switches 25 are turned off, and the bidirectional switching switches 26 are all placed at the collection end 1 , the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12 ; When the fourth grounding switch 25 - 4 is turned on, the other grounding switches 25 are turned off, and the bidirectional switches 26 are all placed at the collection end 1 , the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12 .
[0176] The first controller 22 receives the temperature detection signal of the temperature sensor 14 corresponding to each electrode unit 12 through the analog-to-digital converter 23, and transmits it to the AC signal generator 34 of the electric field generator 30 through the first communication unit 27 and the second communication unit 33, and then controls or adjusts the alternating current signal applied to each electrode unit 12 through the second controller 32.
[0177] When the above methods are applied to the electrode sheets (10D, 10E, 10F, 10G and 10J) of other embodiments, since there are grounding switches 25 in an idle disconnected state and / or bidirectional switching switches 26 in an idle disconnected state on the adapter 20 that are not electrically connected to the corresponding electrode sheets (10D, 10E, 10F, 10G and 10J), the corresponding grounding switches 25 in an idle disconnected state and / or bidirectional switching switches 26 in an idle disconnected state do not need to be controlled accordingly.
[0178] Although various operations are depicted in the drawings as being in a particular order, this should not be understood as requiring that the operations must be performed in the particular order shown or in sequential order, nor should it be understood as requiring that all illustrated operations must be performed to achieve desirable results.
[0179] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them; although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.
Claims
1. An electrode array for applying an alternating current signal, comprising a plurality of electrode units and a plurality of connecting portions connecting two adjacent electrode units, characterized in that: The multiple connecting parts are located between the multiple electrode units and form at least one trunk and multiple branches extending laterally from the trunk with the corresponding electrode units. The relative positions of the electrode units located at the ends of two adjacent branches can be freely adjusted. The multiple electrode units are divided into at least two row groups and at least two column groups in circuit connection. The grounding ends of the electrode units in each row group are grounded through their corresponding grounding wires. The signal input ends of the electrode units in each column group are short-circuited in parallel to their corresponding dual-purpose signal lines. The dual-purpose signal lines transmit direct current signals to the electrode units in the corresponding column groups in conjunction with the grounding wires to collect temperature detection signals of the electrode units or transmit alternating current signals for tumor treatment.
2. The electrode array according to claim 1, characterized in that: Each of the branches is connected to a corresponding electrode unit located on the trunk through a connecting portion, and the electrode units located on adjacent branches are arranged in a disconnected state.
3. The electrode array according to claim 1, characterized in that: The branch at least includes a connecting portion and an electrode unit electrically connected to the connecting portion.
4. The electrode array according to claim 1, characterized in that: The signal input ends of the electrode units in the same row group are connected in parallel through different dual-purpose signal lines, the signal input ends of the electrode units in different column groups are connected in parallel through different dual-purpose signal lines, and the ground ends of the electrode units in the same column group are connected in parallel through different ground lines.
5. The electrode array according to claim 1, characterized in that: The plurality of electrode units are distributed at intervals in the spatial structure to form a plurality of intervals.
6. The electrode array according to claim 5, characterized in that: The interval is located between adjacent branches, and the position between adjacent branches is adjustable.
7. The electrode array according to claim 1, characterized in that: The dual-purpose signal line transmits direct current signals and alternating current signals without overlapping in time.
8. The electrode array according to claim 1, characterized in that: The electrode unit includes a dielectric element for transmitting an AC signal and a temperature sensor for transmitting a DC signal. The ground terminal of the electrode unit is the ground terminal of the temperature sensor. The signal terminal of the temperature sensor is short-circuited with the dielectric element and serves as the signal input terminal of the electrode unit after short-circuiting.
9. The electrode array according to claim 1, characterized in that: The grounding wire and the dual-purpose signal wire are both embedded in the connecting portion.
10. A tumor electric field treatment system, characterized in that: The electrode array comprises the electrode array according to any one of claims 1 to 9.