Water bath method and system for treating osteoporosis based on ultrasonic waves

Abstract

The invention belongs to the technical field of ultrasonic water bath treatment of osteoporosis, and particularly relates to a water bath method and system for treating osteoporosis based on ultrasonic waves. Accurate and personalized treatment of the osteoporosis part is realized by dynamically monitoring and adjusting treatment parameters of ultrasonic waves, firstly, attenuation conditions of the ultrasonic waves in water can be accurately calculated by collecting water medium parameters in real time and constructing an attenuation model, so that the emission frequency is dynamically adjusted, and the treatment accuracy of the osteoporosis part is improved; secondly, by monitoring the energy absorption rate of the osteoporosis part and combining historical treatment data of a patient, a personalized recovery gallery is constructed, the recovery state of the patient can be accurately evaluated, treatment parameters of ultrasonic waves are dynamically adjusted according to the real-time recovery state, and the recovery rate of the osteoporosis part is improved. Compared with a traditional ultrasonic treatment method, the ultrasonic treatment method has the advantages that the treatment accuracy and the individuation degree are improved, and the treatment effect is remarkably enhanced.

Description

Technical Field

[0001] The invention belongs to the technical field of ultrasonic water bath treatment of osteoporosis, and particularly relates to a water bath method and system based on ultrasonic treatment of osteoporosis. Background Art

[0002] Osteoporosis is a systemic bone metabolism disorder, and ultrasound therapy is one of the common methods. Medical ultrasound is mainly applied by direct contact, which is to directly contact the ultrasound head with the skin of the treatment area for treatment, and apply a contact agent such as gel, paraffin oil, vaseline, etc. between the skin and the ultrasound head to reduce the air gap and reduce the attenuation of ultrasound during propagation. However, there are some problems with the direct contact method. For example, the contact agent may cause allergic reactions, and long-term contact may cause skin discomfort. In addition, the direct contact method makes it difficult to ensure that the ultrasonic energy is evenly distributed in the treatment area, thus affecting the treatment effect.

[0003] In response to the above problems, the present invention proposes a water bath method for treating osteoporosis based on ultrasound. The advantage of the underwater method is that the range of ultrasound application is not limited to the area where the ultrasound probe contacts the skin. Ultrasound propagates in water, and the cross-sectional area of ​​the sound field expands with the propagation distance. The part immersed in water can receive ultrasound irradiation over a larger area, thereby expanding the effective area of ​​ultrasound action. Summary of the invention

[0004] The purpose of the present invention is to provide a water bath method and system for treating osteoporosis based on ultrasound, which can achieve effective transmission and uniform distribution of ultrasonic energy at the treatment site, improve the treatment effect, and avoid skin discomfort and allergic reactions that may be caused by direct contact methods.

[0005] The technical solution adopted by the present invention is as follows:

[0006] A water bath method for treating osteoporosis based on ultrasound, comprising:

[0007] Obtain the osteoporotic part of the patient and immerse the osteoporotic part in a water bath environment;

[0008] Apply ultrasonic energy of preset intensity in a water bath environment and monitor the ultrasonic energy absorption rate of the osteoporotic site in real time;

[0009] Deploy a multimodal sensor array in a water bath environment, and collect water medium parameters in the water bath environment in real time through the multimodal sensor;

[0010] The emission frequency of underwater ultrasound is dynamically adjusted according to the water medium parameters so that the ultrasound energy acts on the osteoporotic part of the patient.

[0011] In a preferred embodiment, the water bath temperature of the water bath environment is 37.5°C to 38.5°C, and it is a constant temperature water bath environment, and the osteoporotic part is completely immersed in water.

[0012] In a preferred embodiment, the step of applying ultrasonic energy of a preset intensity in a water bath environment and monitoring the ultrasonic energy absorption rate of the osteoporotic part in real time comprises:

[0013] An ultrasonic generator is used to generate ultrasonic energy of a preset intensity, and the ultrasonic energy is transmitted to the water bath environment through an ultrasonic transducer;

[0014] Real-time monitoring and collection of bone density parameters of osteoporotic areas;

[0015] The change in the bone density parameter is calculated using a sliding time window and recorded as the bone density change parameter, and the energy absorption rate of the osteoporotic site is then determined based on the bone density change parameter.

[0016] In a preferred embodiment, the step of determining the energy absorption rate of the osteoporotic site based on the bone density change parameter comprises:

[0017] Obtain bone density change parameters within a preset time window;

[0018] Collect the total amount of ultrasonic energy input information within a preset time window, including ultrasonic instantaneous power and action duration;

[0019] A calculation function is obtained, and the bone density change parameter, ultrasonic instantaneous power, and action duration are used as input parameters of the calculation function. The energy absorption rate of the osteoporotic part is calculated through the calculation function.

[0020] In a preferred embodiment, the step of dynamically adjusting the emission frequency of underwater ultrasonic waves according to the water medium parameters comprises:

[0021] Real-time acquisition of water medium parameters collected by multimodal sensors, where the water medium parameters include water temperature, water pressure and salinity;

[0022] Obtain the attenuation coefficient of ultrasound in water media, and construct an attenuation model based on the influence of water temperature, water pressure and salinity on ultrasound attenuation;

[0023] Calculate the initial emission frequency of the ultrasonic wave under the current water medium parameters according to the attenuation model;

[0024] Constructing a double verification time window, the double verification time window includes a first verification time window and a second verification time window, the first verification time window corresponds to the end of a previous treatment cycle adjacent to the current treatment cycle, and the second verification time window corresponds to the beginning of the current treatment cycle;

[0025] In the first verification time window, the mean of the patient's bone density change parameter is calculated, and the bone density change reference interval is determined in combination with the peak value of the bone density change parameter;

[0026] In the second verification time window, the patient's bone density change parameters are monitored in real time to obtain a real-time change value of the bone density;

[0027] The real-time change value of bone density is compared with the reference interval of bone density change, and when the real-time change value of bone density is less than the lower limit of the reference interval of bone density change, the initial transmission frequency is increased; when the real-time change value of bone density is within the reference interval of bone density change, or exceeds the reference interval of bone density change, the initial transmission frequency of underwater ultrasound is maintained as the final transmission frequency;

[0028] Among them, after the initial transmission frequency is increased, a third verification time window is constructed;

[0029] If the real-time change value of bone density in the third verification time window is lower than or equal to the real-time change value of bone density in the second verification time window, the initial transmission frequency is adjusted to the final transmission frequency. Otherwise, it stops after the real-time change value of bone density stabilizes within the reference range of bone density change.

[0030] In a preferred embodiment, the step of constructing the attenuation model includes:

[0031] Determine the ultrasonic attenuation coefficient under different combinations of water medium parameters and establish a three-dimensional parameter mapping table, where the three-dimensional parameters include water temperature, water pressure and salinity;

[0032] Real-time measurement of the three-dimensional parameters of the osteoporotic site during water bathing, and matching the corresponding baseline attenuation coefficient from the three-dimensional mapping table;

[0033] The real-time measurement values ​​of the three-dimensional parameters and the reference attenuation coefficient are input into the preset attenuation calculation formula to obtain the dynamic attenuation compensation factor, which is then combined with the reference attenuation coefficient to output the attenuation model representation.

[0034] In a preferred embodiment, after the ultrasonic energy acts on the osteoporotic part of the patient, the energy absorption rate of the osteoporotic part is monitored, and a personalized recovery gallery is constructed based on the patient's treatment data in a historical time period. The specific steps include:

[0035] Collect multi-dimensional treatment data during the patient's treatment cycle, including bone density change rate, energy absorption rate, water medium parameters and ultrasonic frequency;

[0036] Perform time series alignment on multi-dimensional treatment data and construct a correlation dataset with treatment stages as the time axis;

[0037] Vectorize the treatment data in the associated data set and record the historical recovery feature vector;

[0038] Based on the historical response feature vector, trend analysis is performed to generate a reference curve of bone density change trend for multiple treatment cycles in the future, and the physiological intervals of different recovery stages are divided to form a personalized recovery corridor for patients.

[0039] In a preferred embodiment, after the personalized recovery corridor is determined, the step of dynamically adjusting the ultrasonic treatment parameters according to the real-time recovery status of the osteoporotic part of the patient includes:

[0040] Obtain the real-time change value of the patient's bone density during the current treatment cycle and the fluctuation range of water medium parameters;

[0041] Match the real-time change value of bone density with the reference curve of bone density change trend of the corresponding recovery stage in the personalized recovery corridor, and judge whether the real-time recovery state deviates from the corresponding physiological interval;

[0042] When the real-time recovery state deviates from the lower limit of the corresponding physiological interval, the emission frequency in the current ultrasonic treatment parameters is adjusted upward;

[0043] When the real-time recovery state deviates from the upper limit of the corresponding physiological interval, the emission frequency in the current ultrasonic treatment parameter is kept unchanged.

[0044] The present invention also provides a treatment system for treating osteoporosis based on ultrasound, using the above-mentioned water bath method for treating osteoporosis based on ultrasound, comprising:

[0045] An initialization module, used for obtaining the osteoporotic part of the patient and immersing the osteoporotic part into a water bath environment;

[0046] An ultrasonic application module is used to apply ultrasonic energy of a preset intensity in a water bath environment and monitor the ultrasonic energy absorption rate of the osteoporotic part in real time;

[0047] A parameter acquisition module is used to deploy a multimodal sensor array in a water bath environment and to acquire water medium parameters in the water bath environment in real time through the multimodal sensor;

[0048] The ultrasonic adjustment module is used to dynamically adjust the emission frequency of underwater ultrasonic waves according to the water medium parameters, so that the ultrasonic energy acts on the osteoporotic part of the patient.

[0049] And, an electronic device, the electronic device comprising:

[0050] at least one processor;

[0051] and a memory communicatively coupled to the at least one processor;

[0052] The memory stores a computer program executable by the at least one processor, and the computer program is executed by the at least one processor so that the at least one processor can perform the above-mentioned water bath method for treating osteoporosis based on ultrasound.

[0053] The technical effects achieved by the present invention are:

[0054] The present invention realizes accurate and personalized treatment of osteoporotic parts by dynamically monitoring and adjusting ultrasonic treatment parameters. First, by real-time acquisition of water medium parameters and construction of an attenuation model, the attenuation of ultrasonic waves in water can be accurately calculated, thereby dynamically adjusting the transmission frequency to ensure that ultrasonic energy can be effectively transmitted to osteoporotic parts. Secondly, by monitoring the energy absorption rate of osteoporotic parts and building a personalized recovery corridor based on the patient's historical treatment data, the patient's recovery status can be accurately evaluated, and the ultrasonic treatment parameters can be dynamically adjusted according to the real-time recovery status to achieve the best treatment effect. Compared with traditional ultrasonic treatment methods, the present invention not only improves the accuracy and personalization of treatment, but also significantly enhances the treatment effect, providing patients with a more scientific and effective treatment option. BRIEF DESCRIPTION OF THE DRAWINGS

[0055] Figure 1 It is a schematic flow chart of the method of the present invention;

[0056] Figure 2 It is a schematic diagram of the system module of the present invention;

[0057] Figure 3 It is a schematic diagram of the structure of an electronic device of the present invention. DETAILED DESCRIPTION

[0058] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0059] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0060] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure or characteristic that may be included in at least one implementation of the present invention. The phrase "in a preferred embodiment" that appears in different places in this specification does not refer to the same embodiment, nor is it a separate or selective embodiment that is mutually exclusive with other embodiments.

[0061] See also Figure 1 As shown, the present invention provides a water bath method for treating osteoporosis based on ultrasound, comprising:

[0062] S1. Obtain the osteoporotic part of the patient and immerse the osteoporotic part in a water bath environment;

[0063] In step S1, when treating the osteoporotic part of the patient, the osteoporotic part needs to be immersed in a special water bath environment to ensure that the part can fully contact the water medium. The water bath temperature of the water bath environment is 37.5°C to 38.5°C, and it is a constant temperature water bath environment to ensure the stability of ultrasonic propagation. The osteoporotic part is completely immersed in water to ensure that the ultrasonic wave can act evenly on the osteoporotic part, thereby improving the treatment effect.

[0064] S2, applying ultrasonic energy of a preset intensity in a water bath environment, and monitoring the ultrasonic energy absorption rate of the osteoporotic site in real time;

[0065] In step S2, after the osteoporotic part of the patient is placed in the water bath environment, ultrasonic energy of a preset intensity is applied in the water bath environment, and the absorption rate of the ultrasonic energy by the osteoporotic part is monitored in real time to ensure the treatment effect, wherein the step of applying ultrasonic energy of a preset intensity in the water bath environment and monitoring the absorption rate of the ultrasonic energy by the osteoporotic part in real time includes:

[0066] An ultrasonic generator is used to generate ultrasonic energy of a preset intensity, and the ultrasonic energy is transmitted to the water bath environment through an ultrasonic transducer;

[0067] Real-time monitoring and collection of bone density parameters of osteoporotic areas;

[0068] The change of bone density parameters is calculated using a sliding time window and recorded as the bone density change parameter. The energy absorption rate of the osteoporotic part is then determined based on the bone density change parameter.

[0069] Specifically, when ultrasonic energy of a preset intensity is applied in a water bath environment, an ultrasonic generator is used to generate ultrasonic energy that meets the preset intensity requirement, and then the ultrasonic transducer is used to transmit the generated ultrasonic energy to the water bath environment. During the ultrasonic energy transmission process, the bone density parameters of the osteoporotic part are also monitored and accurately collected in real time. Then, a sliding time window technology is used to dynamically analyze the collected bone density parameters, calculate the change amount in different time windows, and record it as a bone density change parameter. Finally, based on the recorded bone density change parameters, the absorption rate of the osteoporotic part to the ultrasonic energy is determined;

[0070] Here, the step of determining the energy absorption rate of the osteoporotic part according to the bone density change parameter includes:

[0071] Obtain bone density change parameters within a preset time window;

[0072] Collect the total amount of ultrasonic energy input information within a preset time window, including ultrasonic instantaneous power and action duration;

[0073] A calculation function is obtained, and the bone density change parameter, ultrasonic instantaneous power, and action duration are used as input parameters of the calculation function, and the energy absorption rate of the osteoporotic part is calculated by the calculation function;

[0074] In the above, after the bone density change parameters are determined, the bone density change parameters within the preset time window are first obtained, and then the total input information of the ultrasonic energy within the same preset time window is collected. The total input information covers the instantaneous power of the ultrasonic wave and its action duration, ensuring that the input of the ultrasonic wave energy can be fully grasped. After that, the measurement function for the energy absorption rate is introduced, and the bone density change parameters, the instantaneous power of the ultrasonic wave and the action duration are used as the input parameters of the measurement function. The energy absorption rate of the osteoporotic part is finally obtained by calculation through the measurement function, wherein the expression of the measurement function is:

[0075]

[0076] Where η represents the ultrasonic energy absorption rate, ΔB represents the bone density transformation parameter within the preset time window, P represents the instantaneous power of the ultrasound, t represents the duration of the ultrasound action, and k represents the conversion coefficient between bone density change and ultrasonic energy.

[0077] S3, deploying a multimodal sensor array in a water bath environment, and collecting water medium parameters in the water bath environment in real time through the multimodal sensor, and dynamically adjusting the emission frequency of underwater ultrasonic waves according to the water medium parameters;

[0078] In step S3, when treating the osteoporotic part of the patient, a multimodal sensor array is first deployed in a water bath environment, and water medium parameters such as water temperature, water pressure, salinity, etc. in the water bath environment are collected in real time by the multimodal sensor, and the emission frequency of underwater ultrasound is dynamically adjusted according to the water medium parameters to optimize the propagation effect of ultrasound. The step of dynamically adjusting the emission frequency of underwater ultrasound according to the water medium parameters includes:

[0079] Real-time acquisition of water medium parameters collected by multimodal sensors, where the water medium parameters include water temperature, water pressure and salinity;

[0080] Obtain the attenuation coefficient of ultrasound in water media, and construct an attenuation model based on the influence of water temperature, water pressure and salinity on ultrasound attenuation;

[0081] Calculate the initial emission frequency of the ultrasonic wave under the current water medium parameters according to the attenuation model;

[0082] Constructing a double verification time window, the double verification time window includes a first verification time window and a second verification time window, the first verification time window corresponds to the end of a previous treatment cycle adjacent to the current treatment cycle, and the second verification time window corresponds to the beginning of the current treatment cycle;

[0083] In the first verification time window, the mean of the patient's bone density change parameter is calculated, and the bone density change reference interval is determined in combination with the peak value of the bone density change parameter;

[0084] In the second verification time window, the patient's bone density change parameters are monitored in real time to obtain a real-time change value of the bone density;

[0085] The real-time change value of bone density is compared with the reference interval of bone density change, and when the real-time change value of bone density is less than the lower limit of the reference interval of bone density change, the initial transmission frequency is increased; when the real-time change value of bone density is within the reference interval of bone density change, or exceeds the reference interval of bone density change, the initial transmission frequency of underwater ultrasound is maintained as the final transmission frequency;

[0086] Among them, after the initial transmission frequency is increased, a third verification time window is constructed;

[0087] If the real-time change value of bone density in the third verification time window is lower than or equal to the real-time change value of bone density in the second verification time window, the initial transmission frequency is adjusted to be the final transmission frequency. Otherwise, the control is stopped after the real-time change value of bone density is stabilized within the reference interval of bone density change.

[0088] Specifically, when dynamically adjusting the emission frequency of underwater ultrasound according to water medium parameters, it is first necessary to obtain the water medium parameters collected by the multimodal sensor in real time. The water medium parameters cover multiple key indicators such as water temperature, water pressure and salinity. Then, it is necessary to clarify the attenuation coefficient of ultrasound in the water medium, and comprehensively consider the specific influence of water temperature, water pressure and salinity on ultrasound attenuation, so as to construct a corresponding attenuation model. Then, according to the constructed attenuation model, the initial emission frequency of ultrasound under the current water medium parameter conditions is calculated. In order to ensure the accuracy and effectiveness of the adjustment process, this embodiment constructs a double verification time window, which is composed of a first verification time window and a second verification time window. The first verification time window corresponds to the end of the previous treatment cycle adjacent to the current treatment cycle, and the second verification time window corresponds to the initial stage of the current treatment cycle. In the first verification time window, the corresponding mean value of the patient's bone density change parameters is calculated, and combined with the peak value data of the bone density change parameters, a reference interval of bone density change is determined. Then, in the second verification time window, the patient The bone density change parameters are monitored in real time to obtain the real-time change value of the bone density, and then the obtained real-time change value of the bone density is compared and analyzed with the previously determined reference interval of the bone density change. When it is found that the real-time change value of the bone density is less than the lower limit of the reference interval of the bone density change, the initial transmission frequency is appropriately increased. When the real-time change value of the bone density is within the reference interval of the bone density change, or exceeds the reference interval of the bone density change, the initial transmission frequency of the underwater ultrasonic wave is maintained as the final transmission frequency. It should be noted that after the initial transmission frequency is increased, a third verification time window is constructed for further verification. If the real-time change value of the bone density is lower than or equal to the real-time change value of the bone density in the second verification time window within the third verification time window, the transmission frequency is adjusted back to the initial transmission frequency and determined as the final transmission frequency. On the contrary, if the real-time change value of the bone density can be stabilized within the reference interval of the bone density change, the further adjustment of the transmission frequency is stopped, otherwise the ultrasonic transmission frequency is continuously adjusted until the real-time change value of the bone density can be stabilized within the reference interval of the bone density change.

[0089] Secondly, the steps of constructing the attenuation model include:

[0090] Determine the ultrasonic attenuation coefficient under different combinations of water medium parameters and establish a three-dimensional parameter mapping table, where the three-dimensional parameters include water temperature, water pressure and salinity;

[0091] Real-time measurement of the three-dimensional parameters of the osteoporotic site during water bathing, and matching the corresponding baseline attenuation coefficient from the three-dimensional mapping table;

[0092] The real-time measurement value of the three-dimensional parameter and the reference attenuation coefficient are input into the preset attenuation calculation formula to obtain the dynamic attenuation compensation factor, and then the dynamic attenuation compensation factor is combined with the reference attenuation coefficient to output the attenuation model representation;

[0093] Specifically, when constructing the attenuation model, it is first necessary to measure the ultrasonic attenuation coefficient under different water medium parameter combinations. By conducting systematic combination tests on different water medium parameters, comprehensive ultrasonic attenuation data is collected, and a three-dimensional parameter mapping table is further established based on this. The three-dimensional parameter mapping table can intuitively reflect the ultrasonic attenuation characteristics under different parameter combinations. Then, when measuring the osteoporotic site in real time for water bath treatment, it is also necessary to measure the three-dimensional parameters in the current environment, namely, water temperature, water pressure and salinity, and compare the real-time measured three-dimensional parameters with the previously established three-dimensional parameter mapping table to match the corresponding benchmark attenuation coefficient (α=κ 1 ·e λT +κ 2 ·P n +κ 3 ln(S+1), where α is the reference attenuation coefficient, κ 1 , κ 2 and κ 3 Respectively represent the contribution weights of water temperature, water pressure and salinity, λ represents the exponential growth rate of water temperature to attenuation, T represents water temperature, P represents water pressure, n represents the power-law nonlinearity of water pressure, S represents salinity), and then, the real-time measured three-dimensional parameter value and the matched reference attenuation coefficient are input into the preset attenuation calculation formula together, and the dynamic attenuation compensation factor is obtained by calculation, wherein the attenuation calculation formula is expressed as: Δα=α-α′, wherein Δα represents the dynamic attenuation compensation factor, α′ represents the reference value of the ultrasonic attenuation coefficient (attenuation coefficient under standard conditions), and the attenuation model can be dynamically adjusted based on the dynamic attenuation compensation factor to adapt to changes in the actual measurement environment, and then, the dynamic attenuation compensation factor is effectively integrated with the reference attenuation coefficient, and finally a comprehensive attenuation model representation is output, wherein the attenuation model is represented as:

[0094] α final =α′+γ·Δα;

[0095] In the formula, α final represents the dynamic attenuation coefficient, and γ is the correction coefficient.

[0096] S4, monitor the energy absorption rate of osteoporotic sites and build a personalized recovery corridor based on the patient's treatment data over a historical period of time;

[0097] In step S4, since different patients have different physiques, their corresponding energy absorption rates and responses to treatment will also be different. Therefore, when monitoring the energy absorption rate of osteoporotic parts, it is necessary to fully consider the individual differences of patients. The main data source is the treatment data of the patients in the past treatment time. Based on this, a personalized recovery gallery corresponding to the patient can be constructed to record the patient's recovery process. Among them, the steps of monitoring the energy absorption rate of osteoporotic parts and constructing a personalized recovery gallery based on the treatment data of the patients in the historical time period include:

[0098] Collect multi-dimensional treatment data during the patient's treatment cycle, including bone density change rate, energy absorption rate, water medium parameters and ultrasonic frequency;

[0099] Perform time series alignment on multi-dimensional treatment data and construct a correlation dataset with treatment stages as the time axis;

[0100] Vectorize the treatment data in the associated data set and record the historical recovery feature vector;

[0101] Based on the historical response feature vector, trend analysis is performed to generate a reference curve of bone density change trend for multiple treatment cycles in the future, and the physiological intervals of different recovery stages are divided to form a personalized recovery corridor for patients;

[0102] Specifically, when constructing a personalized recovery corridor for patients, we first comprehensively collect multi-dimensional treatment data of patients during the treatment cycle. The treatment data include not only the rate of change of bone density to reflect the changes in bone structure, but also the energy absorption rate to evaluate the response of osteoporotic sites to treatment energy. In addition, water medium parameters need to be collected to analyze the water distribution between tissues, as well as ultrasonic frequency data to understand the propagation characteristics of ultrasonic waves in bone tissue. Then, the collected multi-dimensional treatment data are aligned in time series to ensure the consistency of various data on the time axis, which is convenient for subsequent analysis. On this basis, a related data set with the treatment stage as the time axis is constructed to organically integrate various treatment data at different time points, and then the related data are aligned. The centralized treatment data is vectorized and each treatment data is converted into vector form to facilitate mathematical and statistical analysis. At the same time, the historical recovery feature vector is recorded as the basic data for subsequent trend analysis. After that, the corresponding trend analysis is performed based on the historical recovery feature vector. By analyzing the changing patterns of historical data, a reference curve of bone density change trend for multiple treatment cycles in the future is generated, preferably 2 to 3 treatment cycles. Because a large prediction time span will easily lead to increased uncertainty in the prediction results, which will affect the accuracy of the prediction. On this basis, the physiological intervals of different recovery stages are further divided, and the recovery goals and expected effects of each stage are clarified, ultimately forming a personalized recovery corridor for the patient, providing a relatively accurate guidance plan for subsequent treatment.

[0103] S5. Dynamically adjust the ultrasonic treatment parameters according to the patient's personalized recovery corridor and the real-time recovery status of the patient's osteoporotic area;

[0104] In step S5, after the patient's personalized recovery corridor is determined, the ultrasonic treatment parameters, such as intensity, frequency, duration, etc., are dynamically adjusted according to the patient's personalized recovery corridor and the real-time recovery status of the patient's osteoporotic part to ensure the effectiveness and pertinence of the treatment plan. The step of dynamically adjusting the ultrasonic treatment parameters according to the patient's personalized recovery corridor and the real-time recovery status of the patient's osteoporotic part includes:

[0105] Obtain the real-time change value of the patient's bone density during the current treatment cycle and the fluctuation range of water medium parameters;

[0106] Match the real-time change value of bone density with the reference curve of bone density change trend of the corresponding recovery stage in the personalized recovery corridor, and judge whether the real-time recovery state deviates from the corresponding physiological interval;

[0107] When the real-time recovery state deviates from the lower limit of the corresponding physiological interval, the emission frequency in the current ultrasonic treatment parameters is adjusted upward;

[0108] When the real-time recovery state deviates from the upper limit of the corresponding physiological interval, the emission frequency in the current ultrasonic treatment parameter is kept unchanged;

[0109] Specifically, when dynamically adjusting the ultrasonic treatment parameters, it is first necessary to obtain the real-time change value of the patient's bone density during the current treatment cycle, and monitor the fluctuation range of the water medium parameters to ensure the accuracy and comprehensiveness of the data. Secondly, it is necessary to carefully match the acquired real-time change value of bone density with the reference curve of the bone density change trend in the corresponding recovery stage in the personalized recovery corridor. Through comparative analysis, it is determined whether the patient's real-time recovery state deviates from the corresponding physiological interval. If the real-time recovery state deviates from the lower limit of the corresponding physiological interval, the current ultrasonic treatment parameters are adjusted immediately. The specific operation is to increase the emission frequency to enhance the treatment effect. On the contrary, if the real-time recovery state deviates from the upper limit of the corresponding physiological interval, the emission frequency in the current ultrasonic treatment parameters is kept unchanged to maintain the existing treatment intensity and ensure the safety and effectiveness of the treatment.

[0110] See also Figure 2 , a treatment system based on ultrasound for treating osteoporosis, using the above-mentioned water bath method based on ultrasound for treating osteoporosis, comprising:

[0111] An initialization module, used for obtaining the osteoporotic part of the patient and immersing the osteoporotic part into a water bath environment;

[0112] An ultrasonic application module is used to apply ultrasonic energy of a preset intensity in a water bath environment and monitor the ultrasonic energy absorption rate of the osteoporotic part in real time;

[0113] A parameter acquisition module is used to deploy a multimodal sensor array in a water bath environment and to acquire water medium parameters in the water bath environment in real time through the multimodal sensor;

[0114] The ultrasonic adjustment module is used to dynamically adjust the emission frequency of underwater ultrasonic waves according to the water medium parameters, so that the ultrasonic energy acts on the osteoporotic part of the patient.

[0115] Among the above, the main function of the initialization module is to accurately obtain the osteoporotic part of the patient and safely immerse the part into a specially designed water bath environment to ensure that the initial conditions of the treatment process are effectively set. The ultrasonic application module is responsible for applying ultrasonic energy of a preset intensity in the water bath environment, while monitoring the absorption rate of ultrasonic energy by the osteoporotic part in real time to ensure the effectiveness and safety of energy transfer. The parameter acquisition module deploys a multimodal sensor array in the water bath environment, and uses the sensor to collect the water medium parameters in the water bath environment in real time to facilitate subsequent analysis and adjustment of ultrasonic treatment parameters. The ultrasonic adjustment module dynamically adjusts the emission frequency of underwater ultrasonic waves based on the real-time collected water medium parameters to ensure that the ultrasonic energy can accurately act on the osteoporotic part of the patient to achieve the best treatment effect.

[0116] See also Figure 3 , an electronic device, the electronic device comprising:

[0117] at least one processor;

[0118] and a memory communicatively coupled to the at least one processor;

[0119] The memory stores a computer program that can be executed by at least one processor, and the computer program is executed by at least one processor so that the at least one processor can execute the above-mentioned water bath method for treating osteoporosis based on ultrasound.

[0120] The processor of the above-mentioned electronic device can be a central processing unit (CPU), a graphics processing unit (GPU) or a digital signal processor (DSP), the memory can include a read-only memory (ROM), a random access memory (RAM), a flash memory (Flash) or a hard disk memory, etc. The electronic device can also include an operator, an input device and an output device. The operator can be an arithmetic logic unit (ALU) for performing various arithmetic and logical operations, the input device can be a keyboard, a mouse or a touch screen, etc., for receiving user operation instructions; the output device can be a display or a printer, etc., for displaying processing results or outputting reports.

[0121] It should be noted that, in this article, the terms "include", "comprises" or any other variations thereof are intended to cover non-exclusive inclusion, so that a process, device, article or method including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, device, article or method. In the absence of further restrictions, an element defined by the sentence "includes a ..." does not exclude the existence of other identical elements in the process, device, article or method including the element.

[0122] The above is only a preferred embodiment of the present invention. It should be noted that, for those skilled in the art, several improvements and modifications can be made without departing from the principles of the present invention, and these improvements and modifications should also be considered as the protection scope of the present invention. The structures, devices and operating methods not specifically described and explained in the present invention shall be implemented according to the conventional means in the art unless otherwise specified and limited.

Claims

1. A water bath method for treating osteoporosis based on ultrasound, characterized in that: include: Obtain the osteoporotic part of the patient and immerse the osteoporotic part in a water bath environment; Apply ultrasonic energy of preset intensity in a water bath environment and monitor the ultrasonic energy absorption rate of the osteoporotic site in real time; Deploy a multimodal sensor array in a water bath environment, and collect water medium parameters in the water bath environment in real time through the multimodal sensor; The emission frequency of underwater ultrasound is dynamically adjusted according to the water medium parameters so that the ultrasound energy acts on the osteoporotic part of the patient.

2. A water bath method for treating osteoporosis based on ultrasound according to claim 1, characterized in that: The water bath temperature of the water bath environment is 37.5° C. to 38.5° C., and it is a constant temperature water bath environment, and the osteoporotic part is completely immersed in water.

3. A water bath method for treating osteoporosis based on ultrasound according to claim 1, characterized in that: The step of applying ultrasonic energy of a preset intensity in a water bath environment and monitoring the ultrasonic energy absorption rate of the osteoporotic part in real time comprises: An ultrasonic generator is used to generate ultrasonic energy of a preset intensity, and the ultrasonic energy is transmitted to the water bath environment through an ultrasonic transducer; Real-time monitoring and collection of bone density parameters of osteoporotic areas; The change in the bone density parameter is calculated using a sliding time window and recorded as the bone density change parameter, and the energy absorption rate of the osteoporotic site is then determined based on the bone density change parameter.

4. A water bath method for treating osteoporosis based on ultrasound according to claim 3, characterized in that: The step of determining the energy absorption rate of the osteoporotic part according to the bone density change parameter comprises: Obtain bone density change parameters within a preset time window; Collect the total amount of ultrasonic energy input information within a preset time window, including ultrasonic instantaneous power and action duration; A calculation function is obtained, and the bone density change parameter, ultrasonic instantaneous power, and action duration are used as input parameters of the calculation function. The energy absorption rate of the osteoporotic part is calculated through the calculation function.

5. The water bath method for treating osteoporosis based on ultrasound according to claim 1, characterized in that: The step of dynamically adjusting the emission frequency of underwater ultrasonic waves according to the water medium parameters comprises: Real-time acquisition of water medium parameters collected by multimodal sensors, where the water medium parameters include water temperature, water pressure and salinity; Obtain the attenuation coefficient of ultrasound in water media, and construct an attenuation model based on the influence of water temperature, water pressure and salinity on ultrasound attenuation; Calculate the initial emission frequency of the ultrasonic wave under the current water medium parameters according to the attenuation model; Constructing a double verification time window, the double verification time window includes a first verification time window and a second verification time window, the first verification time window corresponds to the end of a previous treatment cycle adjacent to the current treatment cycle, and the second verification time window corresponds to the beginning of the current treatment cycle; In the first verification time window, the mean of the patient's bone density change parameter is calculated, and the bone density change reference interval is determined in combination with the peak value of the bone density change parameter; In the second verification time window, the patient's bone density change parameters are monitored in real time to obtain a real-time change value of the bone density; The real-time change value of bone density is compared with the reference interval of bone density change, and when the real-time change value of bone density is less than the lower limit of the reference interval of bone density change, the initial transmission frequency is increased; when the real-time change value of bone density is within the reference interval of bone density change, or exceeds the reference interval of bone density change, the initial transmission frequency of underwater ultrasound is maintained as the final transmission frequency; Among them, after the initial transmission frequency is increased, a third verification time window is constructed; If the real-time change value of bone density in the third verification time window is lower than or equal to the real-time change value of bone density in the second verification time window, the initial transmission frequency is adjusted to the final transmission frequency. Otherwise, it stops after the real-time change value of bone density stabilizes within the reference range of bone density change.

6. A water bath method for treating osteoporosis based on ultrasound according to claim 5, characterized in that: The step of constructing the attenuation model comprises: Determine the ultrasonic attenuation coefficient under different combinations of water medium parameters and establish a three-dimensional parameter mapping table, where the three-dimensional parameters include water temperature, water pressure and salinity; Real-time measurement of the three-dimensional parameters of the osteoporotic site during water bathing, and matching the corresponding baseline attenuation coefficient from the three-dimensional mapping table; The real-time measurement values ​​of the three-dimensional parameters and the reference attenuation coefficient are input into the preset attenuation calculation formula to obtain the dynamic attenuation compensation factor, which is then combined with the reference attenuation coefficient to output the attenuation model representation.

7. A water bath method for treating osteoporosis based on ultrasound according to claim 6, characterized in that: After the ultrasonic energy acts on the osteoporotic part of the patient, the energy absorption rate of the osteoporotic part is monitored, and a personalized recovery gallery is constructed based on the patient's treatment data in a historical time period. The specific steps include: Collect multi-dimensional treatment data during the patient's treatment cycle, including bone density change rate, energy absorption rate, water medium parameters and ultrasonic frequency; Perform time series alignment on multi-dimensional treatment data and construct a correlation dataset with treatment stages as the time axis; Vectorize the treatment data in the associated data set and record the historical recovery feature vector; Based on the historical response feature vector, trend analysis is performed to generate a reference curve of bone density change trend for multiple treatment cycles in the future, and the physiological intervals of different recovery stages are divided to form a personalized recovery corridor for patients.

8. A water bath method for treating osteoporosis based on ultrasound according to claim 7, characterized in that: After the personalized recovery corridor is determined, the step of dynamically adjusting the ultrasonic treatment parameters according to the real-time recovery status of the osteoporotic part of the patient includes: Obtain the real-time change value of the patient's bone density during the current treatment cycle and the fluctuation range of water medium parameters; Match the real-time change value of bone density with the reference curve of bone density change trend of the corresponding recovery stage in the personalized recovery corridor, and judge whether the real-time recovery state deviates from the corresponding physiological interval; When the real-time recovery state deviates from the lower limit of the corresponding physiological interval, the emission frequency in the current ultrasonic treatment parameters is adjusted upward; When the real-time recovery state deviates from the upper limit of the corresponding physiological interval, the emission frequency in the current ultrasonic treatment parameter is kept unchanged.

9. A therapeutic system for treating osteoporosis based on ultrasound, characterized in that: The water bath method for treating osteoporosis based on ultrasound according to any one of claims 1 to 8 comprises: An initialization module, used for obtaining the osteoporotic part of the patient and immersing the osteoporotic part into a water bath environment; An ultrasonic application module is used to apply ultrasonic energy of a preset intensity in a water bath environment and monitor the ultrasonic energy absorption rate of the osteoporotic part in real time; A parameter acquisition module is used to deploy a multimodal sensor array in a water bath environment and to acquire water medium parameters in the water bath environment in real time through the multimodal sensor; The ultrasonic adjustment module is used to dynamically adjust the emission frequency of underwater ultrasonic waves according to the water medium parameters, so that the ultrasonic energy acts on the osteoporotic part of the patient.

10. An electronic device, characterized in that: The electronic device comprises: at least one processor; and a memory communicatively coupled to the at least one processor; The memory stores a computer program executable by the at least one processor, and the computer program is executed by the at least one processor so that the at least one processor can execute the water bath method for treating osteoporosis based on ultrasound as described in any one of claims 1 to 8.

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