Pickering color-changing lip cream capable of intelligently sensing water content of skin and improving dryness and preparation method of Pickering color-changing lip cream

Abstract

The invention provides a Pickering color-changing lip cream capable of intelligently sensing skin moisture content and improving dryness. The Pickering color-changing lip cream is formed by compounding color-changing Pickering lip cream BSA-AN and cinnamyl aldehyde Pickering lip cream QX. The invention also provides a preparation method and application of the Pickering color-changing lip cream. According to the invention, a Pickering lip emulsion technology is utilized, water-soluble active substances and oily components are organically combined, and the water-soluble active components are ingeniously fused in the water-soluble active substances, so that more excellent active substances are used for lip products. Through the intelligent sensing technology, the lip cream can automatically recognize according to the water content of the lip skin, and reminds to improve the drying and desquamation phenomena in time. The use of a traditional emulsifier is reduced, the irritation to the skin is reduced, and the stability of the product is improved.

Description

Technical Field

[0001] The present invention relates to a Pickering color-changing lip cream that can intelligently sense skin moisture content and improve dryness. Background Art

[0002] As a lip care product, traditional lipsticks are mainly used to moisturize lip skin and improve the health of lip skin. The main ingredients of traditional lipsticks include oily substances such as beeswax and ozokerite. These ingredients give the lipstick good sealing properties, enabling it to form a protective film and reduce the evaporation of lip moisture. However, due to its formula being mainly based on oily ingredients, traditional lipsticks usually cannot add water-soluble active substances such as ergothioneine and hydroxyprogesterone. This results in a relatively single moisturizing function for traditional lipsticks, mainly focusing on providing basic moisturizing effects, while the repair function is relatively weak. In recent years, with the increasing demand for lip care among consumers, lip products have been continuously upgraded. The development from traditional moisturizing lipsticks to intelligent lip creams with multiple functions is an inevitable trend in the market.

[0003] Currently, there have been reports on Pickering lip emulsion technology. Pickering lip emulsion is an emulsion system stabilized by solid particles, which has high stability and does not require traditional emulsifiers, reducing the irritation of chemical emulsifiers to the skin. Using Pickering lip emulsion technology in lip creams can effectively improve the stability and safety of products. For example, in patent application No. 202310521755.5, invention title: A Pickering lip cream without emulsifier and its preparation method, which relates to a Pickering lip cream without emulsifier and its preparation method. The composition of this Pickering lip cream includes oils, solidifying agents, skin feel regulators, stabilizers, moisturizers, preservatives, chelating agents, pH regulators, and water. Among them, specific solidifying agents, skin feel regulators, and pH regulators play a synergistic role, enabling the entire system to form a compact and strong network-like structure, significantly improving the stability of the lip cream. Due to the absence of emulsifiers, the stability of the emulsion disclosed in this literature still has problems and is worse than that of ordinary emulsifiers.

[0004] Currently, intelligent sensing technology has also been applied to lip creams. By adding specific sensing components, lip creams can automatically adjust their colors according to changes in skin moisture content, observe the moisture content of lip skin based on lip color, and promptly improve dryness and peeling. For example, Colorkey's intelligent lip makeup: Colorkey's intelligent lip makeup family adopts the "intelligent adjustment technology", achieving an improvement in makeup feel, touch, and mildness through innovative formulas and color theories. For instance, its third-generation air velvet lip glaze and water mist lip dew enhance the smoothness and moisturizing effect of the lips through the "AiryColorTech native color film" and "β - folded silk protein encapsulation technology". Perfect Diary's biomimetic film essence lipstick: This product pioneered the lip biomimetic film Biolip TM, and has a patented pomegranate peptide complex, combining the effects of lipstick, lip essence, and lip mask. Current commercial products have defects, such as ingredient limitations: although some lip cream products add a variety of plant extracts and moisturizing ingredients, they lack intelligent sensing technology and cannot automatically sense the skin hydration status according to skin water content. Single function: Most lipsticks mainly focus on moisturizing and nourishing functions, and have limited ability to repair deep problems such as dry and peeling lips. Poor stability: As a thermodynamically unstable system, traditional emulsions usually need to add surfactants to reduce the interfacial tension between the oil and water phases to maintain the stability of the system. However, some synthetic small molecule surfactants may pose potential hazards to human health or the environment, so their applications are restricted to a certain extent. In contrast, Pickering lip emulsions achieve stability by forming interfacial films through solid particles adsorbed on the droplet surface, showing more excellent anti-flocculation and anti-coalescence characteristics than traditional emulsions.

[0005] In addition, surfactants disrupt the lip skin barrier function: Surfactants can interact with proteins and lipids in the stratum corneum of the skin, destroying the structural integrity of the stratum corneum. The stratum corneum of the lip skin is thinner, has a fast renewal rate, and lacks melanocytes and sebaceous glands. Traditional surfactants disrupt the organization of the lipid matrix by removing sebum and epidermal lipids, thereby increasing the polarity of the skin and making it easier to damage the lip skin barrier, resulting in dryness and desquamation. Summary of the Invention

[0006] The present invention provides a Pickering color-changing lip emulsion that can intelligently sense skin water content and improve dryness, and a preparation method thereof.

[0007] The present invention provides a Pickering color-changing lip emulsion that can intelligently sense skin water content and improve dryness, which is composed of a color-changing Pickering lip emulsion BSA-AN and a cinnamaldehyde Pickering lip emulsion QX compounded, and their mass ratio is:

[0008] 1-2 parts of the color-changing Pickering lip emulsion BSA-AN, 1-2 parts of the cinnamaldehyde Pickering lip emulsion QX;

[0009] Among them, the color-changing Pickering lip emulsion is prepared from anthocyanin, bovine serum albumin, oil, and sodium hyaluronate as raw materials, and the mass ratio of anthocyanin, bovine serum albumin, oil, and sodium hyaluronate is:

[0010] 0.8-1.2 parts of anthocyanin, 2.4-3.6 parts of bovine serum albumin, 16-24 parts of oil, 0.1-0.3 parts of sodium hyaluronate;

[0011] Among them, the oil is one or more mixtures of jojoba seed oil, sunflower seed oil, shea butter, tocopheryl acetate, diisostearyl malate, and ethylene glycol palmitate;

[0012] The described cinnamaldehyde Pickering lip cream is prepared from cinnamaldehyde, xanthan gum, quaternized chitosan, genipin, and sodium hyaluronate as raw materials. Among them, the mass ratio of cinnamaldehyde, xanthan gum, quaternized chitosan, genipin, and sodium hyaluronate is as follows:

[0013] 8 - 12 parts of cinnamaldehyde, 0.8 - 1.6 parts of xanthan gum, 0.08 - 0.12 parts of quaternized chitosan, 0.5 - 0.9 parts of genipin, and 0.1 - 0.3 parts of sodium hyaluronate.

[0014] Among them, the mass ratio of the raw materials anthocyanin, bovine serum albumin, oil, and sodium hyaluronate in the described color - changeable Pickering lip cream is as follows:

[0015] 1 part of anthocyanin, 3 parts of bovine serum albumin, 20 parts of oil, and 0.2 parts of sodium hyaluronate;

[0016] Among them, the mass ratio of the oil is as follows: 1.5 parts of tocopheryl acetate, 2.5 parts of jojoba seed oil, 6 parts of sunflower seed oil, 2 parts of diisostearyl malate, 2 parts of ethylene glycol palmitate, and 2 parts of shea (BUTYROSPERMUM PARKII) butter;

[0017] The mass ratio of the raw materials cinnamaldehyde, xanthan gum, quaternized chitosan, genipin, and sodium hyaluronate in the described cinnamaldehyde Pickering lip cream is as follows:

[0018] 10 parts of cinnamaldehyde, 1.2 parts of xanthan gum, 0.1 part of quaternized chitosan, 0.7 part of genipin, and 0.2 part of sodium hyaluronate.

[0019] Among them, the raw materials of the described cinnamaldehyde Pickering lip cream also contain a moisturizing component, an antioxidant component, a repair component, an anti - inflammatory component, or a light - protection component.

[0020] Among them, the moisturizing component, antioxidant component, repair component, anti - inflammatory component, or light - protection component includes one or a mixture of two or more of ectoin, hydroxyproline, and ergothioneine.

[0021] The mass ratio of the described ectoin, hydroxyproline, and ergothioneine is 0.5:0.5:0.5, and the total dosage is twice that of quaternized chitosan.

[0022] Among them, the preparation method of the described color - changeable Pickering lip cream includes the following steps:

[0023] b. Weigh the raw materials according to each weight ratio;

[0024] b. Add anthocyanin to bovine serum albumin, stir magnetically at room temperature, add oil and mix evenly, and then add sodium hyaluronate, and homogenize at a speed of 16000 r / min for 2 min to obtain it.

[0025] The preparation method of the cinnamaldehyde Pickering lip milk includes the following steps:

[0026] a. Take moisturizing ingredients, antioxidant ingredients, repair ingredients, anti-inflammatory ingredients or photoprotective ingredients, dissolve them in water, add quaternized chitosan and sodium hyaluronate, adjust the pH value to 5.5, stir at a speed of 3000 r / min for 2 - 3 h, transfer the stirred solution to an ultrasonic processor, set the power to 300 W, and perform ultrasonic treatment for 10 min to promote the formation of micelles; put the solution after ultrasonic treatment into a dialysis bag for dialysis;

[0027] b. Dissolve xanthan gum in water and stir at a speed of 3000 r / min for 20 min;

[0028] c. Mix the xanthan gum solution prepared in step b with the micelles prepared in step a, stir at a speed of 3000 r / min for 30 min to form aggregates; add cinnamaldehyde and homogenize at a speed of 25000 r / min for 10 min; then slowly dropwise add a crosslinking agent while stirring, and let it stand to obtain the product; the crosslinking agent is genipin.

[0029] Further preferably, the mass ratio of the color - changeable Pickering lip milk BSA - AN to the cinnamaldehyde Pickering lip milk is;

[0030] 1 part of the color - changeable Pickering lip milk BSA - AN and 1 part of the cinnamaldehyde Pickering lip milk QX.

[0031] The present invention also provides a method for preparing the intelligent induction Pickering color - changeable lip milk for skin water content and improving dryness, which includes the following steps:

[0032] a. Take raw materials in each weight ratio;

[0033] b. After mixing, disperse at a speed of 10000 r / min on a homogenizer for 2 min, and pause every 30 s to obtain the product.

[0034] The use of the Pickering color - changeable lip milk in the preparation of drugs or functional cosmetics for preventing cheilitis or lip desquamation.

[0035] The inventor found in the experiment that the stabilities of the single color - changeable Pickering lip milk BSA - AN and the cinnamaldehyde Pickering lip milk QX both have problems, but after compounding the two, better stability can be achieved.

[0036] The present invention utilizes Pickering lip emulsion technology to organically combine water-soluble active substances with oily components, skillfully incorporate water-soluble active ingredients into them, and enable more excellent active substances to be used in lip products. Through intelligent sensing technology, the lip cream can automatically identify according to the water content of the lip skin and remind to timely improve dryness and peeling. The use of traditional emulsifiers is reduced, the irritation to the skin is decreased, and at the same time, the stability of the product is enhanced. Description of the Drawings

[0037] Figure 1 Appearance of QX Pickering lip emulsion with different ratios;

[0038] Figure 2 Appearance of QX-BSA-AN Pickering lip emulsion with different ratios;

[0039] Figure 3 Microscopic image of QX-BSA-AN Pickering lip emulsion with different ratios;

[0040] Figure 4 Design concept diagram;

[0041] Figure 5 Average particle size distribution diagram;

[0042] Figure 6 Average particle size distribution diagram;

[0043] Figure 7 Effect diagram of using QX-BSA-AN lip cream;

[0044] Figure 8 Change in water content of using QX-BSA-AN lip cream. Detailed Description of the Invention

[0045] Example 1 Preparation of Pickering color-changing lip emulsion of the present invention for intelligent sensing of skin water content and improvement of dryness

[0046] (1) Weigh 0.5 g of ectoin, 0.5 g of hydroxyprolisilane, and 0.5 g of ergothioneine, add them to 100 g of water, stir evenly to completely dissolve each component. Then add 0.1 g of Quaternized Chitosan and 0.2 g of sodium hyaluronate, adjust the pH value to 5.5 with citric acid, stir at a speed of 3000 r / min for 2 - 3 h, transfer the stirred solution to an ultrasonic processor, set the power to 300 W, and perform ultrasonic treatment for 10 min to promote the formation of micelles. Load the ultrasonically treated solution into a dialysis bag and dialyze with ionized water for 24 h, changing the dialysis solution every 4 h to remove unself-assembled materials and improve the purity of the micelles.

[0047] (2) 1.2 g of xanthan gum was dissolved in 100 g of water, stirred at 3000 r / min for 20 min, mixed with the micelles prepared in step (1), and stirred at 3000 r / min for 30 min to form aggregates. The mixing mass ratios were 1:2, 1:1, and 2:1 respectively;

[0048] (3) Add 50 ml of 200 mg / mL cinnamaldehyde to step (2), homogenize at 25,000 r / min for 10 min, then slowly add 70 ml of genipin (1 mg / ml) dropwise while stirring, let stand for 12 h, and mark as QX emulsion.

[0049] like Figure 1 As shown, after 12 hours of placement, the 2:1 QX emulsion was the most stable, and this QX emulsion was selected to continue the experiment.

[0050] (4) Prepare 100 ml of 30 mg / mL bovine serum albumin, add 10 ml of 100 mg / ml anthocyanidins, stir magnetically at room temperature for 10 min, add 3 g of tocopherol acetate, 5 g of jojoba seed oil, 6 g of sunflower seed oil, 2 g of diisostearyl malate, 2 g of ethylene glycol palmitate, and 2 g of avocado tree (BUTYROSPERMUM PARKII) fruit fat, mix well, add 0.2 g of sodium hyaluronate, and homogenize at 16,000 r / min for 2 min. Label it as BSA-AN emulsion.

[0051] (5) BSA-AN emulsion and QX emulsion were dispersed in different proportions on a homogenizer at a speed of 10,000 r / min for 2 min, and the mixture was paused every 30 s. According to the mass ratio of QX emulsion to BSA-AN emulsion (2:1, 1:1, 1:2), the emulsions were marked as samples 1, 2, and 3, and the one without QX emulsion was marked as sample 4.

[0052] like Figure 2 , Figure 3 As shown, due to the stabilizing effect of solid particles, the oil droplets of Pickering lip lotion may present a more regular shape, such as a circle or an ellipse, rather than being randomly deformed, and the size of the oil droplets may vary due to the size and distribution of the solid particles, but it is usually relatively uniform. No. 1 has a cream-like appearance, and the microscopic morphology shows relatively dispersed oil droplets of varying sizes; No. 2 has a cream-like appearance, and the oil droplets under the microscope are densely distributed, and the oil droplets are of relatively consistent size, showing good stability; No. 3 has a cream-like appearance, and the oil droplets are sparsely distributed, and the oil droplets are of varying sizes, and the stability is weak; No. 4 has an emulsion-like appearance, with higher fluidity, denser distribution of oil droplets, and relatively consistent oil droplet size. No. 2 is selected, that is, 1:1, and QX-BSA-AN Pickering lip emulsion lip cream is selected as the final product.

[0053] The above tests prove that there are problems with the stability of the color-changing Pickering lip cream BSA-AN and the cinnamaldehyde Pickering lip cream QX when used alone. Only when the multiple emulsions are prepared in a specific ratio can the higher quality requirements be met.

[0054] (6) The design idea is as Figure 4 、 Figure 5 shown. The obtained lip cream is the QX-BSA-AN Pickering lip cream, and the average particle size is 80 μm.

[0055] Example 2 Performance test of the Pickering color-changing lip cream of the present invention

[0056] 1. Color test on skin with different humidities

[0057] The QX-BSA-AN Pickering lip cream was applied to skin models with different water contents. The results are as Figure 6 shown. When the QX-BSA-AN Pickering lip cream was applied to the skin model with a water content of 80 a.u., it presented a deep pink color; when applied to the skin model with a water content of 60 a.u., it presented a light pink color; when applied to the skin model with a water content of 40 a.u., it was similar to the original color of the model, being beige or light brown; when applied to the skin model with a water content of 60 a.u., it presented a brown or gray color. This formula can intelligently sense the water content. Anthocyanins present one color in a low-humidity environment. When the environmental humidity increases, the hydroxyl groups in the anthocyanin molecular structure interact with water molecules. At high humidity, the color is more vivid, and the combination of anthocyanin molecules and water molecules is more stable, resulting in a change in its absorption spectral characteristics and thus presenting different colors.

[0058] 2. Study on the improvement effect on lip dryness.

[0059] In this test, subjects with lip dryness meeting relevant standards were included. According to the pre-test results, the predicted sample size using PASS was 12 people. After the subjects cleaned the skin of the test area, they rested in a constant temperature and humidity rest room in the test center for 20 min, and basic data (base) were collected. Then, the QX-BSA-AN Pickering lip cream was used, and data were collected 1 h, 3 h, and 1 week after use.

[0060] The data collected included 4 aspects,

[0061] ① Safety evaluation: The doctor's score for adverse reactions on the facial skin, and the number of cases of adverse reactions was counted; ② Doctor's efficacy evaluation: dryness, fine lines, scales, chapping, elasticity, fullness, and glossiness; ③ Self-evaluation: Using the self-perception evaluation form of the subjects, dryness, fine lines, scales, chapping, elasticity, fullness, and glossiness; ④ Non-invasive instrument test of the following skin physiological parameters: TEWL, water content, and chromaticity image.

[0062] After use, no adverse reactions occurred, and doctors and self-assessments showed improvements in dryness, fine lines, scaling, chapping, elasticity, plumpness, and glossiness.

[0063] Specific images are as Figure 7 shown. After 1 hour of use, fine lines, desquamation, etc. improved rapidly. After 3 hours of use, scaling, etc. recovered compared to 1 hour, but after 1 week of use, dryness, fine lines, scaling, chapping, etc. were significantly alleviated, and elasticity, plumpness, and glossiness were all improved.

[0064] The water content is as Figure 8 shown. The baseline water content of the lip skin of people with dry lips is extremely low. After 1 hour of use, the water content increased rapidly. It decreased slightly in the initial maintenance period, but after 1 week of use, the water content of the lip skin increased significantly.

[0065] Modern life is stressful, and long-term bad living habits are important factors leading to cheilitis and dry lips. For example, behaviors such as licking lips, biting lips, and peeling skin repeatedly stimulate the lip skin, resulting in inflammation and dryness. In addition, staying up late, long-term smoking, drinking alcohol, and frequent use of cosmetics containing irritating ingredients (such as lipsticks and lip balms) also increase the risk of cheilitis. With the increasing awareness of lip care among consumers, the market size of lip care products is constantly expanding. In 2024, the global lip care market size reached 260 million US dollars and is expected to grow at a compound annual growth rate of 5.3% in the next few years. This indicates that more and more people are starting to pay attention to lip health, and the demand for products to relieve cheilitis and dry lips is also increasing. The present invention relates to a lip balm that, through intelligent sensing technology, enables the lip cream to automatically identify according to the water content of the lip skin and reminds to replenish water in a timely manner, early preventing cheilitis and lip exfoliation caused by dryness and water shortage.

Claims

1. A Pickering color-changing lip cream that intelligently senses skin moisture content and improves dryness, characterized in that: It is a compound of color-changing Pickering Lip Cream BSA-AN and cinnamaldehyde Pickering Lip Cream QX, and the mass ratio is: 1-2 parts of color-changing Pickering Lip Cream BSA-AN, 1-2 parts of cinnamaldehyde Pickering Lip Cream QX; The color-changing Pickering lip cream is prepared from anthocyanidin, bovine serum albumin, oil, and sodium hyaluronate as raw materials, and the mass ratio of anthocyanidin, bovine serum albumin, oil, and sodium hyaluronate is: 0.8-1.2 parts of anthocyanin, 2.4-3.6 parts of bovine serum albumin, 16-24 parts of oil, 0.1-0.3 parts of sodium hyaluronate; The oil is one or a mixture of two or more of jojoba seed oil, sunflower seed oil, avocado oil, tocopherol acetate, diisostearyl malate, and ethylene glycol palmitate; The cinnamaldehyde Pickering lip lotion is prepared from cinnamaldehyde, xanthan gum, quaternary ammonium chitosan, genipin, and sodium hyaluronate as raw materials, wherein the mass ratio of cinnamaldehyde, xanthan gum, quaternary ammonium chitosan, genipin, and sodium hyaluronate is: 8-12 parts of cinnamaldehyde, 0.8-1.6 parts of xanthan gum, 0.08-0.12 parts of quaternized chitosan, 0.5-0.9 parts of genipin, and 0.1-0.3 parts of sodium hyaluronate.

2. The Pickering color-changing lip cream for intelligently sensing skin moisture content and improving dryness according to claim 1, characterized in that: The mass ratio of the raw materials anthocyanin, bovine serum albumin, oil and sodium hyaluronate in the color-changing Pickering lip lotion is: 1 part of anthocyanin, 3 parts of bovine serum albumin, 20 parts of oil, 0.2 parts of sodium hyaluronate; The mass ratio of the oils and fats is: 1.5 parts of tocopherol acetate, 2.5 parts of jojoba seed oil, 6 parts of sunflower seed oil, 2 parts of diisostearyl malate, 2 parts of ethylene glycol palmitate, and 2 parts of avocado tree (BUTYROSPERMUM PARKII) fruit fat; The mass ratio of the raw materials cinnamaldehyde, xanthan gum, quaternized chitosan, genipin and sodium hyaluronate in the cinnamaldehyde Pickering lip lotion is: 10 parts of cinnamaldehyde, 1.2 parts of xanthan gum, 0.1 parts of quaternized chitosan, 0.7 parts of genipin, and 0.2 parts of sodium hyaluronate.

3. The Pickering color-changing lip cream for intelligently sensing skin moisture content and improving dryness according to claim 2, characterized in that: The raw materials of the cinnamaldehyde Pickering lip lotion also contain moisturizing ingredients, antioxidant ingredients, repairing ingredients, anti-inflammatory ingredients or light protection ingredients.

4. The Pickering color-changing lip cream for intelligently sensing skin moisture content and improving dryness according to claim 3, characterized in that: The moisturizing ingredient, antioxidant ingredient, repair ingredient, anti-inflammatory ingredient or light protection ingredient includes one or a mixture of two or more of ectoine, bosoneine and ergothioneine.

5. The Pickering color-changing lip cream for intelligently sensing skin moisture content and improving dryness according to claim 4, characterized in that: The mass ratio of ectoine, bosylamine and ergothioneine is 0.5:0.5:0.5, and the total dosage is twice that of quaternized chitosan.

6. The Pickering color-changing lip cream for intelligently sensing skin moisture content and improving dryness according to any one of claims 1 to 5, characterized in that: The preparation method of the color-changing Pickering lip cream comprises the following steps: a. Weigh the raw materials of each weight ratio; b. Add anthocyanin to bovine serum albumin, stir magnetically at room temperature, add oil and mix evenly, add sodium hyaluronate, and homogenize at a speed of 16000r / min for 2min to obtain; The preparation method of the cinnamaldehyde Pickering lip lotion comprises the following steps: a. Take moisturizing ingredients, antioxidant ingredients, repair ingredients, anti-inflammatory ingredients or light protection ingredients, add water to dissolve, add quaternized chitosan and sodium hyaluronate, adjust the pH value to 5.5, stir at a speed of 3000r / min for 2-3h, transfer the stirred solution to an ultrasonic processor, set the power to 300W, and perform ultrasonic treatment for 10min to promote the formation of micelles; put the ultrasonically treated solution into a dialysis bag for dialysis; b. Dissolve xanthan gum in water and stir at 3000r / min for 20min; c. Mix the xanthan gum solution prepared in step b with the micelles prepared in step a, and stir at a speed of 3000 r / min for 30 min to form aggregates; add cinnamaldehyde and homogenize at a speed of 25000 r / min for 10 min; then slowly add a crosslinking agent dropwise while stirring and let stand to obtain; the crosslinking agent is genipin.

7. The Pickering color-changing lip cream for intelligently sensing skin moisture content and improving dryness according to any one of claims 1 to 5, characterized in that: The mass ratio of the color-changing Pickering lip lotion BSA-AN to the cinnamaldehyde Pickering lip lotion is: 1 part of color-changing Pickering Lip Cream BSA-AN and 1 part of cinnamaldehyde Pickering Lip Cream QX.

8. A method for preparing the Pickering color-changing lip cream for intelligently sensing skin moisture content and improving dryness as described in claims 1-7, characterized in that: It includes the following steps: a. Take raw materials of various weight proportions; b. After mixing, disperse it on a homogenizer at a speed of 10000r / min for 2 minutes, and pause every 30 seconds.

9. Use of the Pickering color-changing lip cream according to any one of claims 1 to 7 in the preparation of medicines or functional cosmetics for preventing cheilitis or lip flaking.

Images