Optical detection system and sample analyzer comprising same

Abstract

The invention relates to an optical detection system and a sample analyzer comprising the same. The optical detection system comprises: a first light source assembly comprising a first light emitting unit for emitting a first light beam; the second light source assembly comprises a dichroscope and a second light emitting unit used for emitting a second light beam, the dichroscope is located on light paths of the first light beam and the second light beam, and the dichroscope can allow the first light beam to penetrate through and is used for reflecting the second light beam; the focusing lens is positioned on the light path of the first light beam and the reflected second light beam and is used for focusing the transmitted first light beam or the reflected second light beam to form a first detection light beam; the shaping module comprises a light guide part and a light uniformizing part, the light guide part and the light uniformizing part are sequentially arranged and extend in the light emitting direction of the first detection light beam, and the light guide part is used for guiding the first detection light beam to meet the requirement that the first detection light beam is coupled into the light uniformizing part at the uniformizing angle in the light uniformizing part. The optical detection system and the sample analyzer comprising the optical detection system have high detection accuracy.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and particularly to an optical detection system and a sample analyzer including the same. Background Art

[0002] Optical analysis method is one of the methods commonly used for sample analysis in the current market. Due to its excellent cost advantage and wide application range, optical analysis method has been favored by various manufacturers in recent years. In principle, optical analysis method refers to a method in which a light source irradiates a sample to be measured, and by detecting and recording the changes in scattered light or transmitted light caused by the sample to be measured, the specific properties of the substance to be analyzed in the sample to be measured are calculated and analyzed.

[0003] As a key measurement system of a sample analyzer, the number of detection channels supported by an optical detection system directly affects the detection speed, and the number of detection wavelengths supported by it directly determines the types of detection items. To meet the detection requirements, an optical detection system with multiple wavelengths and multiple detection channels has emerged. However, in the related art, the detection accuracy of the existing optical detection system with multiple wavelengths and multiple detection channels is not high, resulting in poor detection effects. Summary of the Invention

[0004] Based on this, it is necessary to provide an optical detection system and a sample analyzer including the same that can improve the detection accuracy for the above problems.

[0005] An optical detection system, the optical detection system includes:

[0006] A first light source module, including:

[0007] A first light source assembly, including a first light emitting unit for emitting a first light beam;

[0008] A second light source assembly, including a dichroic mirror and a second light emitting unit for emitting a second light beam. The dichroic mirror is located on the optical paths of the first light beam and the second light beam. The dichroic mirror can allow the first light beam to pass through and is used to reflect the second light beam. The optical axis of the first light beam is perpendicular to the optical axis of the second light beam before reflection and coincides with the optical axis of the second light beam after reflection; and

[0009] A focusing mirror, located on the optical path of the first light beam and used to focus the transmitted first light beam or the reflected second light beam to form a first detection light beam; and

[0010] A shaping module, including a light guiding member and a light homogenizing member. The light guiding member and the light homogenizing member are arranged and extended in sequence along the light emitting direction of the first detection light beam. The light guiding member is used to guide the first detection light beam to be coupled into the light homogenizing member at an angle that satisfies homogenization within the light homogenizing member.

[0011] An optical detection system, the optical detection system comprising:

[0012] A first light source module, comprising:

[0013] A first light source assembly, comprising a first light emitting unit for emitting a first light beam;

[0014] A second light source assembly, comprising a dichroic mirror and a second light emitting unit for emitting a second light beam, the dichroic mirror being located on the optical paths of the first light beam and the second light beam, the dichroic mirror being capable of allowing the first light beam to pass through and being used for reflecting the second light beam, the optical axis of the first light beam being perpendicular to the optical axis of the second light beam before reflection and coinciding with the optical axis of the reflected second light beam; and

[0015] A focusing mirror, located on the optical path of the first light beam and being used for focusing the transmitted first light beam or the reflected second light beam to form a first detection light beam; and

[0016] A shaping module, comprising a light guiding member and a light homogenizing member, the light guiding member and the light homogenizing member being arranged and extending in sequence along the light emitting direction of the first detection light beam, the light guiding member being a light guiding optical fiber, the light homogenizing member being a light homogenizing rod, the light guiding member being used for guiding the first detection light beam to be coupled into the light homogenizing member at an angle that satisfies total internal reflection and homogenization within the light homogenizing member.

[0017] In some embodiments, the first light emitting unit comprises a first light source, a first filter mirror and a first collimating mirror, the first light source being used for emitting the first light beam, the first filter mirror being used for filtering the first light beam, and the first collimating mirror being used for collimating the first light beam;

[0018] The second light emitting unit comprises a second light source, a second filter mirror and a second collimating member, the second light source being used for emitting the second light beam, the second filter mirror being used for filtering the second light beam, and the second collimating member being used for collimating the second light beam.

[0019] In some embodiments, the wavelength of the first light beam is greater than the wavelength of the second light beam;

[0020] Define the connection line between the geometric center of the dichroic mirror and the optical center of the focusing mirror as the first optical axis, the optical axis of the first light beam being offset relative to the first optical axis in the direction in which the second light beam enters the dichroic mirror, and the offset distance L1 satisfying the condition: 0.1 mm ≤ L1 ≤ 2 mm.

[0021] In some of these embodiments, there are multiple groups of the second light source components, and all the second light source components are arranged in sequence along the light-emitting direction of the first light beam. In this direction, the wavelength of the second light beam emitted by each of the second light source components gradually decreases.

[0022] In some of these embodiments, a line connecting the geometric center of the dichroic mirror and the optical center of the focusing mirror is defined as the first optical axis, and an axis passing through the geometric center of the dichroic mirror and perpendicular to the first optical axis is defined as the second optical axis;

[0023] Among the second light source components between the second light source component farthest from the first light-emitting unit and the first light source component, the optical axis of the second light beam is offset relative to the second optical axis in the light-emitting direction of the first light beam, and the offset distance L2 satisfies the condition: 0.1 mm ≤ L2 ≤ 2 mm.

[0024] In some of these embodiments, the distance between the light homogenizing member and the light guiding member is K1, and 1 mm ≤ K1 ≤ 3 mm.

[0025] In some of these embodiments, a first detection module is further included. The first detection module includes a beam splitting detection optical fiber and a plurality of first detection positions. The beam splitting end of the beam splitting detection optical fiber has a plurality of beam splitting parts, and all the beam splitting parts correspond to all the first detection positions one by one;

[0026] The beam splitting detection optical fiber is used to separate the homogenized first detection light beam through each of the beam splitting parts to the corresponding first detection positions.

[0027] In some of these embodiments, the beam splitting detection optical fiber is a multi-core optical fiber. The multi-core optical fiber includes a plurality of sub-optical cores, and each of the sub-optical cores has a relatively arranged sub-combining part and a sub-beam splitting part;

[0028] At the combining end of the beam splitting detection optical fiber, the sub-combining parts of all the sub-optical cores form a plurality of layers around; at the beam splitting end of the beam splitting detection optical fiber, the sub-beam splitting parts of all the sub-optical cores are evenly divided into a plurality of the beam splitting parts;

[0029] In each of the beam splitting parts, there is a sub-beam splitting part that is optically connected to the sub-combining parts of each of the layers.

[0030] In some of these embodiments, the distance between the light homogenizing member and the beam splitting detection optical fiber is K2, and 1 mm ≤ K2 ≤ 3 mm.

[0031] In some of these embodiments, a second light source module and a second detection module are further included;

[0032] The second detection module includes a plurality of second detection positions. The second light source module is configured to emit a second detection light beam towards the second detection positions, and the wavelength of the second detection light beam is less than the wavelength of the first detection light beam.

[0033] In some embodiments, the second light source module includes a third light source, a third filter, and a third collimator. The third light source is configured to emit a second detection light beam, the third filter is configured to filter the second detection light beam, and the third collimator is configured to collimate the second detection light beam.

[0034] A sample analyzer includes the optical detection system according to any one of the above embodiments. The optical detection system is configured to perform optical detection on a sample to be measured.

[0035] For the above optical detection system and the sample analyzer including the same, since the energy distribution of the spot formed by the first detection light beam homogenized by the homogenizing member is uniform, the energy of the subsequent first detection light beam can be evenly separated and used for detection. Consequently, the detection accuracy of the optical detection system is also improved. Description of the Drawings

[0036] Figure 1 It is a schematic structural diagram of an optical detection system in an embodiment of the present application.

[0037] Figure 2 For Figure 1 It is a schematic structural diagram of the first light source module in the optical detection system shown.

[0038] Figure 3 For Figure 1 It is a schematic structural diagram of the cooperation between the shaping module and the first detection module in the optical detection system shown.

[0039] Figure 4 For Figure 1 It is a schematic diagram of the transmission of the first detection light beam in the light homogenizing member after being adjusted by the light guiding member in the optical detection system shown.

[0040] Figure 5 For Figure 1 It is a comparison diagram of the spots formed by the first light source assembly and each second light source assembly at the beam combining end of the beam splitting detection optical fiber in the optical detection system shown.

[0041] Figure 6 For Figure 1 It is a cross-sectional view of the beam splitting end when the optical core of the beam splitting detection optical fiber shown is a single-core optical core in the optical detection system shown.

[0042] Figure 7 For the Figure 6 It is a spectrogram of the spot formed by one of the beam splitting portions after beam splitting using the beam splitting detection optical fiber shown.

[0043] Figure 8 For the spectral diagram of the light spot formed by another beam splitting part after the beam splitting of the beam splitting detection optical fiber shown in Figure 6 .

[0044] Figure 9 For the spectral diagram of the light spot formed by yet another beam splitting part after the beam splitting of the beam splitting detection optical fiber shown in Figure 6 .

[0045] Figure 10 For Figure 1 the cross-sectional view of the combined end when the optical core of the beam splitting detection optical fiber in the optical detection system shown in is a multi-core optical core.

[0046] Figure 11 This is the structural schematic diagram of the optical detection system in another embodiment of the present application.

[0047] Figure 12 For Figure 11 the structural schematic diagram of the cooperation between the second light source module and the second detection module in the optical detection system shown in.

[0048] Reference numerals in the drawings:

[0049] 1. Optical detection system;

[0050] 10. First light source module; 20. Shaping module; 30. First detection module; 40. Second light source module; 50. Second detection module; 60. Signal receiving module; 70. Light source control circuit module;

[0051] 11. Focusing mirror; 12. First light source assembly; 121. First light emitting unit; 121a. First light source; 121b. First filter; 121c. First collimating mirror; 13. Second light source assembly; 131. Second light emitting unit; 131a. Second light source; 131b. Second filter; 131c. Second collimating mirror; 132. Dichroic mirror;

[0052] 21. Light guiding member; 22. Light homogenizing member;

[0053] 31. Beam splitting detection optical fiber; 311. Optical core; 311a. Sub-optical core; 311b. Sub-combined part; 311c. Sub-beam splitting part; 312. Beam splitting part; 32. First detection position; 33. First photoelectric conversion element;

[0054] 41. Third light source; 42. Third filter; 43. Third collimating member;

[0055] 51. Second detection position; 52. Second photoelectric conversion element. Detailed implementation manners

[0056] To make the above objects, features, and advantages of the present application more apparent and understandable, the following describes the specific embodiments of the present application in detail with reference to the accompanying drawings. Many specific details are set forth in the following description to facilitate a thorough understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without departing from the spirit of the present application. Therefore, the present application is not limited by the specific embodiments disclosed below.

[0057] In the description of the present application, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. These are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation on the present application.

[0058] In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of these features. In the description of the present application, the meaning of "a plurality" is at least two, such as two, three, etc., unless otherwise specifically defined.

[0059] In the present application, unless otherwise clearly specified and limited, the terms "mounted", "connected", "coupled", "fixed", etc. should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or integrated; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the internal communication of two elements or the interaction relationship between two elements, unless otherwise clearly limited. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific circumstances.

[0060] In the present application, unless otherwise clearly specified and limited, the first feature being "on" or "under" the second feature can be that the first and second features are in direct contact, or the first and second features are indirectly in contact through an intermediate medium. Moreover, the first feature being "above", "over", and "on top of" the second feature can be that the first feature is directly above or obliquely above the second feature, or simply indicates that the first feature has a higher horizontal height than the second feature. The first feature being "under", "beneath", and "underneath" the second feature can be that the first feature is directly below or obliquely below the second feature, or simply indicates that the first feature has a lower horizontal height than the second feature.

[0061] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or there may also be an intermediate element. When an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intermediate element at the same time. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used herein are only for illustrative purposes and do not represent the only implementation.

[0062] Please refer to Figure 1 , this application provides an optical detection system 1, and the optical detection system 1 includes a first light source module 10, a shaping module 20, a first detection module 30 and a signal receiving module 60. The first light source module 10 is used to emit a first detection beam, the shaping module 20 is used to shape the first detection beam and couple it into the first detection module 30, the first detection module 30 uses the shaped first detection beam to detect a sample to be detected and generate a photoelectric signal, and the signal receiving module 60 is used to receive the photoelectric signal and obtain the result of the analysis and detection.

[0063] Please refer to Figure 2 , Figure 3 and Figure 4 , wherein, the first light source module 10 includes a first light source component 12, a second light source component 13 and a focusing mirror 11. The first light source component 12 includes a first light emitting unit 121 for emitting a first beam, the second light source component 13 includes a dichroic mirror 132 and a second light emitting unit 131 for emitting a second beam, the dichroic mirror 132 is located on the optical paths of the first beam and the second beam, and the dichroic mirror 132 can allow the first beam to pass through and is used to reflect the second beam. The optical axis of the first beam is perpendicular to the optical axis of the second beam before reflection and coincides with the optical axis of the reflected second beam. The focusing mirror 11 is located on the optical path of the first beam and is used to focus the transmitted first beam or the reflected second beam to form a first detection beam.

[0064] Optionally, the second light source component 13 can be one group or multiple groups. If there are multiple groups, all the second light source components 13 are arranged in sequence along the light emitting direction of the first beam, and the wavelengths of the second beams emitted by different second light source components 13 are all different. The wavelengths of the second beams emitted by each second light source component 13 are also different from the wavelength of the first beam emitted by the first light source component 12. Different wavelengths are used to implement different detection items.

[0065] As an example, taking Figure 2 as an example, the wavelength of the first beam is greater than the wavelength of any one of the second beams, and in the light emitting direction of the first beam, the wavelengths of the second beams emitted by each second light source component 13 gradually decrease. In the light emitting direction of the first beam (atFigure 2 In the horizontal direction (from left to right), the wavelength of the first light beam is in the range of 780 nm - 820 nm, such as 810 nm. The wavelength of the second light beam emitted by the first second light source assembly 13 is in the range of 625 nm - 680 nm, such as 660 nm. The wavelength of the second light beam emitted by the second second light source assembly 13 is in the range of 565 nm - 590 nm, such as 575 nm. The wavelength of the second light beam emitted by the third second light source assembly 13 is in the range of 385 nm - 430 nm, such as 405 nm. The wavelength of the second light beam emitted by the fourth second light source assembly 13 is in the range of 320 nm - 350 nm, such as 340 nm.

[0066] The dichroic mirror 132 is arranged at the junction of the first light beam and the second light beam in a manner that is inclined 45° relative to both the first light beam and the unreflected second light beam. The dichroic mirror 132 can transmit light beams of certain wavelengths and can reflect light beams of other wavelengths. Specifically, in the present application, the dichroic mirror 132 can reflect the second light beams emitted by the second light emitting units 131 within the same group and can transmit the first light beam and the second light beams emitted by the second light source assemblies 13 in different groups.

[0067] Within the same time period, the focusing mirror 11 can only focus the first light beam or the second light beam. In different time periods, the focusing mirror 11 can focus the first light beam and the second light beam. Among them, the first light beam emitted by the first light emitting unit 121 of the first light source assembly 12 passes through the dichroic mirrors 132 of each second light source assembly 13 in sequence and is focused by the focusing mirror 11. The second light beams emitted by the second light emitting units 131 of the second light source assemblies 13 are reflected by the dichroic mirrors 132 within the same group and then pass through the other dichroic mirrors 132 located between the dichroic mirrors 132 within the same group and the focusing mirror 11 in sequence and are focused by the focusing mirror 11.

[0068] To Figure 2For example, the first light beam emitted by the first light source component 12 is sequentially transmitted through the dichroic mirrors 132 of the first second light source component 13, the second second light source component 13, the third second light source component 13, and the fourth second light source component 13, and then focused by the focusing mirror 11. The second light beam emitted by the first second light source component 13 is reflected by the dichroic mirror 132 of the first second light source component 13, and then sequentially transmitted through the dichroic mirrors 132 of the second second light source component 13, the third second light source component 13, and the fourth second light source component 13, and then focused by the focusing mirror 11. The second light beam emitted by the second light source component is reflected by the dichroic mirror 132 of the second light source component, and then sequentially transmitted through the dichroic mirrors 132 of the third second light source component 13 and the fourth second light source component 13, and then focused by the focusing mirror 11. The second light beam emitted by the third light source component is reflected by the dichroic mirror 132 of the third light source component, and then transmitted through the dichroic mirror 132 of the fourth second light source component 13 and then focused by the focusing mirror 11. The second light beam emitted by the fourth light source component is reflected by the dichroic mirror 132 of the fourth light source component and then focused by the focusing mirror 11.

[0069] The shaping module 20 includes a light guiding member 21 and a light homogenizing member 22. The light guiding member 21 and the light homogenizing member 22 are sequentially arranged and extended along the light emitting direction of the first detection light beam. The light guiding member 21 is used to guide the first detection light beam to be coupled into the light homogenizing member 22 at an angle that satisfies homogenization within the light homogenizing member 22.

[0070] The light guiding member 21 can be an optical fiber, a lens group, etc. The light guiding member 21 is used to adjust the angle at which the first detection light beam enters the light homogenizing member 22, so that the first detection light beam can be coupled into the light homogenizing member 22 at an angle that satisfies homogenization within the light homogenizing member 22, improving the reliability of homogenization by the homogenizing member. In this way, the energy distribution of the light spot formed after the first detection light beam is homogenized within the light homogenizing member 22 is uniform. The light homogenizing member 22 can be a light homogenizing rod, a compound eye lens, etc., and can be specifically selected according to needs. Taking the light homogenizing member 22 as a light homogenizing rod as an example, the angle at which the light guiding member 21 is used to guide the first detection light beam to be coupled into the light homogenizing member 22 is in the range of 23° to 43°.

[0071] Please refer to again Figure 1, the first detection module 30 includes a beam-splitting detection optical fiber 31, a plurality of first detection positions 32, and a plurality of first photoelectric conversion components 33. The beam-splitting end of the beam-splitting detection optical fiber 31 has a plurality of beam-splitting parts 312, and all the beam-splitting parts 312 are in one-to-one correspondence with all the first detection positions 32 and all the first photoelectric conversion components 33. The beam-splitting detection optical fiber 31 is used to separate the homogenized first detection light beam to the corresponding first detection positions 32 through the respective beam-splitting parts 312, and react with the samples to be detected at each first detection position 32 to form photoelectric signals. Each first photoelectric conversion component 33 receives the optical signals of the first detection position 32 corresponding to itself and forms electrical signals to be fed back to the signal receiving module 60. The signal receiving module 60 calculates and analyzes the specific properties of the substances to be analyzed in the samples to be detected at each first detection position 32, so as to provide a judgment basis for clinical diagnosis.

[0072] The beam-splitting parts 312 form detection channels for separating the first detection light beam. Therefore, the number of beam-splitting parts 312 determines the number of detection channels. By setting a plurality of beam-splitting parts 312, the optical detection system 1 has a plurality of detection channels and can detect a plurality of samples to be detected at the same time, improving the detection speed and having a high detection efficiency. In order to increase the number of detection channels, the number of beam-splitting parts 312 at the beam-splitting end of the beam-splitting detection optical fiber 31 is generally more than 20, and can be 26, 28, 30, etc. In addition, since the first light source module 10 can also emit first detection light beams with different wavelengths at different time periods, the optical detection system 1 can also execute different detection items at different time periods, forming an optical detection system 1 with multiple detection channels and multiple detection items.

[0073] Since the spot energy distribution of the first detection light beam formed by the homogenized light emitted by the homogenizing component is uniform, the energy of the first detection light beam can be evenly separated to each beam-splitting part 312, ensuring that each subsequent first detection position 32 has a high detection accuracy. Accordingly, the detection accuracy of the optical detection system 1 is also improved.

[0074] Please refer to again Figure 3 and Figure 4 , in some embodiments of the present application, the light guiding component 21 is a light guiding optical fiber, and the light homogenizing component 22 is a light homogenizing rod. The light guiding component 21 is used to guide the first detection light beam to be coupled into the light homogenizing component 22 at an angle that satisfies total internal reflection within the light homogenizing component 22.

[0075] In this embodiment, please refer to Figure 4When the light guide 21 guides the first detection light beam to be coupled into the light homogenizer 22 at an angle that satisfies total internal reflection within the light homogenizer 22, the angle range is within 23° to 43°. The material for making the light homogenizing rod can be glass, fused quartz, etc. The length of the light homogenizing rod can be 25 mm, 50 mm, 100 mm, etc. As an example, the cross-section of the light homogenizing rod can be a square, a regular hexagon, etc. The material selection, length, and shape of the light homogenizing rod can all be adjusted according to needs and are not limited here.

[0076] When a light beam enters from a medium with a larger refractive index into a medium with a smaller refractive index, if the incident angle is greater than the critical angle, the light beam will be completely reflected back into the original medium. The light homogenizing rod utilizes this principle to achieve homogenization of the light beam by causing total internal reflection within it.

[0077] In the related art where the optical detection system 1 does not have a light guiding optical fiber, when the light homogenizing rod extends along the light output direction of the first detection light beam, the first detection light beam emitted by the focusing mirror 11 enters the light homogenizing rod parallelly, resulting in the first detection light beam not completing total internal reflection within the light homogenizing rod but basically passing through directly, rendering the light homogenizing rod ineffective; therefore, the optical detection system 1 requires a shaping component that can preferably adjust the incident angle of the first detection light beam into the light homogenizer 22 to control the angle of the first detection light beam to achieve the function of the light homogenizing rod.

[0078] To solve the above problems, the solution of using a light guiding optical fiber can achieve control of the angle of the first detection light beam. The light receiving angle of the light guiding optical fiber is large, and correspondingly, the light output angle of the light guiding optical fiber is also large. In this way, the light guiding optical fiber can shape the first detection light beam with a larger angle to be incident on the light homogenizing rod, making the first detection light beam more compatible with the light homogenization mechanism of the light homogenizing rod and improving the reliability of light homogenization. At the same time, because the light receiving angle of the light guiding optical fiber is large, the energy of the first detection light beam emitted by the condenser lens can basically be captured by the light guiding optical fiber, with small energy loss and high detection accuracy.

[0079] To reduce the volume of the optical detection system 1, a light guiding optical fiber with a shorter length can also be set, for example, 100 mm. In this way, the light guiding optical fiber does not occupy too much space, and the volume of the entire optical detection system 1 is reduced.

[0080] Please refer to again Figure 3 In some embodiments of the present application, the distance between the light homogenizer 22 and the light guide 21 is K1, where 1 mm ≤ K1 ≤ 3 mm, and the distance between the light homogenizer 22 and the beam splitting detection optical fiber 31 is K2, where 1 mm ≤ K2 ≤ 3 mm.

[0081] The distance between the light homogenizer 22 and the beam splitting detection optical fiber 31 specifically refers to the distance between the light homogenizer 22 and the end face of the combined end of the beam splitting detection optical fiber 31.

[0082] Generally, to improve the optical coupling efficiency and reduce the influence of stray light, an antireflection film is further coated outside the light homogenizing member 22 to improve the transmittance of the first detection light beam for detection. The distance between the light homogenizing member 22 and the light guiding member 21 and the distance between the light homogenizing member 22 and the beam splitting detection optical fiber 31 are too close. During the installation process, both the light guiding member 21 and the beam splitting detection optical fiber 31 are likely to scratch the antireflection film on the surface of the light homogenizing member 22, affecting the subsequent detection effect. If the distance between the light homogenizing member 22 and the light guiding member 21 and the beam splitting detection optical fiber 31 is too far, it is likely to cause a reduction in the optical coupling efficiency between the light homogenizing member 22 and the light guiding member 21, as well as between the light homogenizing member 22 and the beam splitting detection optical fiber 31, thereby resulting in a lower detection accuracy.

[0083] In this application, by designing the distance between the light homogenizing member 22 and the light guiding member 21 as K1, where 1 mm ≤ K1 ≤ 3 mm, and the distance between the light homogenizing member 22 and the beam splitting detection optical fiber 31 as K2, where 1 mm ≤ K2 ≤ 3 mm, a suitable distance is reserved between the light homogenizing member 22 and the light guiding member 21 and between the light homogenizing member 22 and the beam splitting detection optical fiber 31 for installation and optical coupling, reducing the probability of damaging the antireflection film on the surface of the light homogenizing member 22 during the installation process and improving the optical coupling efficiency. Moreover, 1 mm ≤ K1 ≤ 3 mm and 1 mm ≤ K2 ≤ 3 mm also make the structure between the light homogenizing member 22 and the light guiding member 21, as well as between the light homogenizing member 22 and the beam splitting detection optical fiber 31, compact, which is beneficial to reducing the size of the entire optical detection system 1.

[0084] Please refer to again Figure 2 , further, in some embodiments of the present application, the first light emitting unit 121 includes a first light source 121a, a first filter 121b, and a first collimating mirror 121c. The first light source 121a is used to emit a first light beam, the first filter 121b is used to filter the first light beam, and the first collimating mirror 121c is used to collimate the first light beam and form a first light beam.

[0085] The second light emitting unit 131 includes a second light source 131a, a second filter 131b, and a second collimating member. The second light source 131a is used to emit a second light beam, the second filter 131b is used to filter the second light beam, and the second collimating member is used to collimate the second light beam and form a second light beam.

[0086] Among them, the first light source 121a and each second light source 131a can both be light emitting diodes (LEDs).

[0087] The first light source 121a and all the second light sources 131a operate in sequence according to a stroboscopic driving method with a certain cycle. The lighting duration can be 20 ms - 50 ms, such as 25 ms. The so-called stroboscopic driving method with a certain cycle in sequence means that among the first light source 121a and all the second light sources 131a, if one light source operates, the other light sources are extinguished. After a lighting duration, this light source is extinguished, the next light source is lit, and all the other light sources are extinguished. Then, the other unlit light sources are lit in sequence. When all the light sources have completed the lighting and extinguishing actions, one stroboscopic cycle is completed.

[0088] Taking Figure 2 as an example, if the second light source 131a of the fourth second light source assembly 13 is lit, the other light sources are extinguished. After a lighting duration, the second light source 131a of the fourth second light source assembly 13 is extinguished, the second light source 131a of the third second light source assembly 13 is lit, and all the other light sources are extinguished. Then, the second light source 131a of the second second light source assembly 13, the second light source 131a of the first second light source assembly 13, and the first light source 121a of the first light source assembly 12 are lit in sequence. When the first light source 121a has completed the lighting and extinguishing steps, one stroboscopic cycle is completed.

[0089] The first filter 121b is used to purify the first light beam, and the second filter 131b is used to purify the second light beam emitted by the second light source 131a within the same group.

[0090] Taking Figure 2 as an example, the first filter 121b can transmit light beams with a wavelength of 810 ± 10 nm, the second filter 131b in the first second light source assembly 13 can transmit light beams with a wavelength of 660 ± 10 nm, the second filter 131b in the second second light source assembly 13 can transmit light beams with a wavelength of 575 ± 10 nm, the second filter 131b in the third second light source assembly 13 can transmit light beams with a wavelength of 405 ± 10 nm, and the second filter 131b in the fourth second light source assembly 13 can transmit light beams with a wavelength of 340 ± 10 nm.

[0091] The first collimating mirror 121c is used to collimate the first light beam, and the second collimating mirror 131c is used to collimate the second light beam purified by the second filter within the same group, in preparation for the focusing of the subsequent focusing mirror 11.

[0092] When the light beam passes through the collimating mirror, a refraction phenomenon occurs, enabling the light beam to be focused into a parallel light beam. Taking Figure 2For example, the first light beam formed after being collimated by the first collimating mirror 121c is irradiated horizontally and parallelly onto the focusing mirror 11, and the second light beam formed after being collimated by the second collimating mirror 131c is irradiated vertically onto the dichroic mirror 132, and is horizontally reflected onto the focusing mirror 11 under the reflection of the dichroic mirror 132.

[0093] By setting the first light source 121a, the first filter 121b and the first collimating mirror 121c, the first light beam formed has high purity and good parallelism. Similarly, by setting the second light source 131a, the second filter 131b and the second collimating mirror 131c, the second light beam formed has high purity and good parallelism. The light beam with high purity can be free from the influence of other stray light during the detection process, and the detection accuracy is high. The light beam with good parallelism has a large spot energy after focusing, and has high detection sensitivity during subsequent beam splitting and detection.

[0094] Please refer to Figure 2 and Figure 5 , in some embodiments of the present application, the wavelength of the first light beam is greater than the wavelength of the second light beam; define the connection line between the geometric center of the dichroic mirror 132 and the optical center of the focusing mirror 11 as the first optical axis (as shown by X in Figure 2 ), the optical axis of the first light beam is offset relative to the first optical axis in the direction in which the second light beam enters the dichroic mirror 132, and the offset distance L1 satisfies the condition: 0.1 mm ≤ L1 ≤ 2 mm. Define the axis passing through the geometric center of the dichroic mirror 132 and perpendicular to the first optical axis as the second optical axis (as shown by Y in Figure 2 ); in the second light source assembly 13 between the second light source assembly 13 which is the farthest from the first light emitting unit 121 and the first light source assembly 12, the optical axis of the second light beam is offset relative to the second optical axis in the light emitting direction of the first light beam, and the offset distance L2 satisfies the condition: 0.1 mm ≤ L2 ≤ 2 mm.

[0095] Due to the certain thickness and refractive index of the dichroic mirror 132, the light beam will have different degrees of offset when passing through. Different light sources pass through different numbers of dichroic mirrors 132, and the positions of the focusing mirror 11, the light guiding member 21, the light homogenizing member 22 and the beam splitting and detecting optical fiber 31 are fixed, which will cause different degrees of offset in the positions of the spots of light beams with different wavelengths finally reaching the combining end of the beam splitting and detecting optical fiber 31. If the offset of the offset spot is not adjusted, the coupling efficiency into the beam splitting and detecting optical fiber 31 will be reduced, resulting in a decrease in the optical power of each beam splitting part 312.

[0096] To solve the above problems, this solution fine-tunes the optical paths of each wavelength to make the positions of the spots incident on the beam splitting and detecting optical fiber 31 basically consistent. Specifically, with Figure 2 and Figure 4For example, according to the refraction theory, the optical path of the light beam after passing through the dichroic mirror 132 will shift upward, and finally the spot incident on the beam splitting detection optical fiber 31 will also shift upward. Therefore, to overlap the spots, it is necessary to adjust the optical path.

[0097] The more the number of light beams passing through the dichroic mirror 132, the greater the upward shift of the spot incident on the combined beam end of the beam splitting detection optical fiber 31. Taking Figure 2 and Figure 5 as examples, the second light beam emitted by the second light emitting unit 131 in the fourth second light source assembly 13 is directly reflected by the dichroic mirror 132. Since the second light beam emitted by the second light emitting unit 131 in the fourth second light source assembly 13 does not pass through the dichroic mirror 132 during transmission, therefore, the spot position formed by the second light beam emitted by the second light emitting unit 131 in the fourth second light source assembly 13 at the beam splitting detection optical fiber 31 is the most accurate, and it has a high optical coupling efficiency with the beam splitting detection optical fiber 31. The second light beams emitted by the second light emitting units 131 of the second second light source assembly 13, the third second light source assembly 13, and the fourth second light source assembly 13, and the first light beam emitted by the first light source assembly 12 pass through an increasing number of dichroic mirrors 132. Therefore, the upward shift amounts of the spots formed by the four different wavelength light beams at the beam splitting detection optical fiber 31 also gradually increase.

[0098] Specifically, reference can be made to Figure 5 , in Figure 5 , spot A is the spot formed by the first light beam emitted by the first light source assembly 12 at the combined beam end of the beam splitting detection optical fiber 31. Spot B is the spot formed by the second light beam emitted by the second light emitting unit 131 of the first second light source assembly 13 at the combined beam end of the beam splitting detection optical fiber 31, spot C is the spot formed by the second light beam emitted by the second light emitting unit 131 of the second second light source assembly 13 at the combined beam end of the beam splitting detection optical fiber 31, spot D is the spot formed by the second light beam emitted by the third second light source assembly 13 at the combined beam end of the beam splitting detection optical fiber 31, spot E is the spot formed by the second light beam emitted by the second light emitting unit 131 of the fourth second light source assembly 13 at the combined beam end of the beam splitting detection optical fiber 31. In Figure 5 , the upward shift amounts of spots D, C, B, and A relative to spot E gradually increase.

[0099] Please refer to again Figure 3, in the present application, by setting the optical axis of the first light-emitting unit 121 to be offset relative to the first optical axis in the light-emitting direction of the second light beam, and the offset distance L1 satisfying the condition: 0.1 mm ≤ L1 ≤ 2 mm, moreover, the optical axis of the second light-emitting unit 131 is offset relative to the second optical axis in the light-emitting direction of the first light beam, and the offset distance L2 satisfies the condition: 0.1 mm ≤ L2 ≤ 2 mm. In this way, the offset light spots move downward, so that the light spots overlap. That is to say, the light spots formed by the first detection light beams of different wavelengths overlap at the combining end of the beam-splitting detection optical fiber 31. Under this design, the first detection light beams of different wavelengths and the beam-splitting detection optical fiber 31 both have a high coupling efficiency. Consequently, the detection sensitivity and detection accuracy of the optical detection system 1 are also improved.

[0100] In some embodiments of the present application, the beam-splitting detection optical fiber 31 is a multi-core optical fiber and includes a plurality of optical cores 311. Each optical core 311 has a combining portion and a beam-splitting portion 312 arranged opposite to each other. All the combining portions are located at the combining end of the beam-splitting detection optical fiber 31, and all the beam-splitting portions 312 are located at the beam-splitting end of the beam-splitting detection optical fiber 31.

[0101] Please refer to Figure 6 、 Figure 7 and Figure 8 , in some embodiments, each optical core 311 is a single-core optical core. In this embodiment, the total number of beam-splitting portions 312 of all the optical cores 311 is the same as the number of detection channels.

[0102] Specifically, as shown in Figure 6 、 Figure 7 、 Figure 8 and Figure 9 , in Figure 6 , the multi-core optical fiber has 23 optical cores 311. Each optical core 311 has a beam-splitting portion 312, and the 23 optical cores 311 form 23 detection channels. In this embodiment, the energy magnitude and energy distribution of the first detection light beam emitted from the beam-splitting portion 312 of each optical core 311 are the same, and it has a high detection accuracy. Specifically, as shown in Figure 7 、 Figure 8 and Figure 9 . As shown in Figure 7 、 Figure 8 and Figure 9 , Figure 7 、 Figure 8 and Figure 9 are spectrograms of the light spots formed by the first detection light beams emitted from any 3 beam-splitting portions 312 after the beam-splitting of the beam-splitting detection optical fiber 31. In Figure 7 、 Figure 8 and Figure 9 , the abscissa represents the diameter size of the light spot formed by the light beam emitted from the beam-splitting portion 312 hitting the first detection position 32, and the ordinate represents the energy magnitude distribution on the diameter of the light spot. From Figure 7 、 Figure 8 and​​​​​​​​​​​​Figure 9 It can be seen that the diameter of the light spot formed by each beam splitting part 312 hitting the first detection position 32 is basically in the span range of -80 to +80. That is to say, the diameter is basically 160 units, and the sizes of the light spots are basically the same. The energy of the light spot is also basically concentrated in the range of -70 to +70, and the energy value of the light spot is basically about 50. That is to say, the sizes of the light spots formed by the light beams emitted by each beam splitting part 312 hitting the first detection position 32 are basically the same, the energy distributions are the same, and the energy sizes are also basically the same. Both the energy size and the energy distribution are relatively uniform.

[0103] Please refer to Figure 10 , in some other embodiments, the optical core 311 includes a plurality of sub-optical cores 311a. Each sub-optical core 311a has a relatively arranged sub-combining part 311b and a sub-beam splitting part 311c; at the combining end of the beam splitting detection optical fiber 31, the sub-combining parts 311b of all the sub-optical cores 311a form a plurality of circles; at the beam splitting end of the beam splitting detection optical fiber 31, the sub-beam splitting parts 311c of all the sub-optical cores 311a are evenly divided into a plurality of beam splitting parts 312; in each beam splitting part 312, there is a sub-beam splitting part 311c that is optically connected to the sub-combining part 311b of each circle.

[0104] That is to say, in this embodiment, each optical core 311 is a multi-core optical core 311. Each optical core 311 includes a plurality of sub-optical cores 311a. Each sub-optical core 311a is a single-core optical core, and the number of sub-optical cores 311a included in each optical core 311 can be set as needed. For example, when the number of detection channels is 23, there are 23 optical cores 311, and each optical core 311 includes 10 sub-optical cores 311a. In this way, the entire multi-core optical fiber has 230 sub-optical cores 311a.

[0105] In the related art, the beam splitting detection optical cores 311 with multi-core optical cores 311 all adopt manual beam splitting. Taking the number of detection channels being 23 and each optical core 311 including 10 sub-optical cores 311a as an example, there are 230 sub-optical fibers in the beam splitting detection optical core 311. During manual beam splitting, 10 sub-optical cores 311a are randomly picked up as a bundle to form an optical core 311.

[0106] When the optical detection system 1 fails and the homogenization effect of the light homogenizing member 22 is poor, at the combining end of the beam splitting detection optical fiber 31, the closer the sub-combining part 311b in the circle is to the central axis of the beam splitting detection optical fiber 31 in the radial direction of the beam splitting detection optical fiber 31, the higher the energy of the first detection light beam obtained by the sub-combining part 311b; the farther the sub-combining part 311b in the circle is from the central axis of the beam splitting detection optical fiber 31 in the radial direction of the beam splitting detection optical fiber 31, the lower the energy of the first detection light beam obtained by the sub-combining part 311b.

[0107] Taking Figure 10For example, all the sub-combining parts 311b at the combining end are roughly divided into 6 layers. In the radial direction of the beam splitting detection optical fiber 31, the 6 layers are layer R1, layer R2, layer R3, layer R4, layer R5, and layer R6, and the energy of the sub-combining parts 311b in layer R1, layer R2, layer R3, layer R4, layer R5, and layer R6 gradually decreases.

[0108] In this way, if the sub-combining parts 311b of any 10 sub-optical cores 311a are all located in the layer closer to the central axis of the beam splitting detection optical fiber 31 in the radial direction of the beam splitting detection optical fiber 31, the energy of the formed optical core 311 is large. If the sub-combining parts 311b of any 10 sub-optical cores 311a are all located in the layer farther from the central axis of the beam splitting detection optical fiber 31 in the radial direction of the beam splitting detection optical fiber 31, the energy of the formed optical core 311 is small. Due to the uncertainty of manual beam splitting, the energy size distribution of each optical core 311 is uneven, and the detection accuracy is reduced.

[0109] In the present application, in each beam splitting part 312, there is a sub-beam splitting part 311c that is optically connected to the sub-combining parts 311b of each layer. That is to say, each optical core 311 is composed of the sub-optical cores 311a where the sub-combining parts 311b of each layer are located. During actual operation, at least one sub-optical core 311a is extracted from each layer and combined to form an optical core 311. In this way, the energy size distribution of each optical core 311 is relatively uniform, which is beneficial to improving the detection accuracy.

[0110] Please refer to Figure 11 and Figure 12 , in some embodiments of the present application, the optical detection system 1 further includes a second light source module 40 and a second detection module 50; the second detection module 50 includes a plurality of second detection positions 51, the second light source module 40 is used to emit a second detection beam to the second detection positions 51, and the wavelength of the second detection beam is less than the wavelength of the first detection beam.

[0111] The first light source module 10 and the second light source module 40 are used in different time periods. That is to say, when either the first light source module 10 or the second light source module 40 is working, the other is turned off.

[0112] Preferably, the wavelength of the second detection beam is in the range of 100 nm to 380 nm.

[0113] The optical power of the second detection beam with a smaller wavelength is small. After being split by multiple beam splitting parts 312, the energy of the second detection beam is greatly reduced and the anti-interference ability is poor, resulting in a reduced reception sensitivity of the first optoelectronic conversion component 33.

[0114] Therefore, directly isolating the second detection beam with a shorter wavelength and directly guiding the second detection beam to the second detection station can improve the light intensity and anti-interference ability during the detection of the second detection beam with a short wavelength, ensuring the detection accuracy of the detection items corresponding to the second detection beam.

[0115] For Figure 2 example, the optical detection system 1 includes a first light source module 10 and a second light source module 40. The first light source module 10 is used to emit the first detection beam in four wavelength ranges, which are the ranges of 780nm - 820nm, 625nm - 680nm, 565nm - 590nm, and 385nm - 430nm respectively. The second light source module 40 is used to emit the second detection beam with a wavelength in the range of 320nm - 350nm.

[0116] In some embodiments of the present application, the second light source module 40 includes a third light source 41, a third filter 42, and a third collimator 43. The third light source 41 is used to emit the second detection beam, the third filter 42 is used to filter the second detection beam, and the third collimator 43 is used to collimate the second detection beam.

[0117] The third filter 42 is used to purify the second detection beam. For Figure 2 example, the third filter 42 can transmit the second detection beam with a wavelength of 340 ± 10nm. The third collimator is used to collimate the second detection beam. After the second detection beam is collimated, it is directly injected into the third detection position and reacts with the sample to be measured.

[0118] By setting the third light source 41, the third filter 42, and the third collimator, the formed second detection beam has high purity and good parallelism. The second detection beam with high purity can be free from the influence of other stray light during the detection process, and the detection accuracy is high. The second detection beam with good parallelism can be concentrated and injected into the second detection position 51, which is beneficial to improving the sensitivity of subsequent detection.

[0119] In addition, during the process of the light beam passing through the dichroic mirror 132, there will be losses in the light beam. In the second light source module 40, due to the reduction of the setting of the dichroic mirror 132, the total light transmittance of the second detection beam increases, the power is enhanced, and the detection effect is better.

[0120] In the present application, the optical detection system 1 further includes a light source control circuit module 70. The light source control circuit module 70 is electrically connected to the first light source module 10 and the second light source module 40. The light source control circuit module 70 is used to control the first light source module 10 and the second light source module 40 to perform the detection of corresponding detection items.

[0121] The optical detection system 1 in the present application has the following advantages:

[0122] 1. The function of multi-detection channel detection is realized, greatly improving the detection speed and significantly reducing the detection pressure.

[0123] 2. The difference in uneven channel energy distribution caused by multi-detection channel detection is effectively solved, improving the accuracy and repeatability of detection.

[0124] 3. The detection of multiple wavelengths is realized, and multi-item detection can be supported.

[0125] This application also includes a sample analyzer, which includes the optical detection system 1 described in any of the above embodiments. The optical detection system 1 is used to perform optical detection on the sample to be tested.

[0126] Among them, the sample analyzer can be a coagulation analyzer, an excrement analyzer, etc.

[0127] The sample analyzer in this application has the effects brought by any of the above embodiments, so it will not be elaborated here.

[0128] The technical features of the above embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the technical features in the above embodiments are described. However, as long as these technical feature combinations do not conflict, they should be considered as the scope described in this specification.

[0129] The above embodiments only represent several implementation manners of this application. Their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the patent application. It should be noted that for those of ordinary skill in the art, without departing from the concept of this application, several modifications and improvements can still be made, and these all belong to the protection scope of this application. Therefore, the protection scope of the patent of this application should be subject to the appended claims.

Claims

1. An optical detection system, characterized in that, the optical detection system includes: A first light source module (10), including: A first light source assembly (12), including a first light emitting unit (121) for emitting a first light beam; A second light source assembly (13), including a dichroic mirror (132) and a second light emitting unit (131) for emitting a second light beam, the dichroic mirror (132) is located on the optical paths of the first light beam and the second light beam, the dichroic mirror (132) can allow the first light beam to pass through and is used for reflecting the second light beam, the optical axis of the first light beam is perpendicular to the optical axis of the second light beam before reflection and coincides with the optical axis of the second light beam after reflection; and A focusing mirror (11), located on the optical path of the first light beam and used for focusing the first light beam passing through or the reflected second light beam to form a first detection light beam; and A shaping module (20), including a light guiding member (21) and a light homogenizing member (22), the light guiding member (21) and the light homogenizing member (22) are arranged and extended in sequence along the light emitting direction of the first detection light beam, the light guiding member (21) is used for guiding the first detection light beam to be coupled into the light homogenizing member (22) at an angle that satisfies homogenization within the light homogenizing member (22).

2. An optical detection system, characterized in that, the optical detection system includes: A first light source module (10), including: A first light source assembly (12), including a first light emitting unit (121) for emitting a first light beam; A second light source assembly (13), including a dichroic mirror (132) and a second light emitting unit (131) for emitting a second light beam, the dichroic mirror (132) is located on the optical paths of the first light beam and the second light beam, the dichroic mirror (132) can allow the first light beam to pass through and is used for reflecting the second light beam, the optical axis of the first light beam is perpendicular to the optical axis of the second light beam before reflection and coincides with the optical axis of the second light beam after reflection; and A focusing mirror (11), located on the optical path of the first light beam and used for focusing the passed first light beam or the reflected second light beam to form a first detection light beam; and A shaping module (20), including a light guiding member (21) and a light homogenizing member (22), the light guiding member (21) is a light guiding optical fiber, the light homogenizing member (22) is a light homogenizing rod, the light guiding member (21) is used for guiding the first detection light beam to be coupled into the light homogenizing member (22) at an angle that satisfies total reflection and homogenization within the light homogenizing member (22).

3. The optical detection system according to claim 1 or 2, characterized in that, The first light-emitting unit (121) includes a first light source (121a), a first filter (121b), and a first collimator (121c). The first light source (121a) is configured to emit the first light beam, the first filter (121b) is configured to filter the first light beam, and the first collimator (121c) is configured to collimate the first light beam; The second light-emitting unit (131) includes a second light source (131a), a second filter (131b), and a second collimating member (131c). The second light source (131a) is configured to emit the second light beam, the second filter (131b) is configured to filter the second light beam, and the second collimating member (131c) is configured to collimate the second light beam.

4. The optical detection system according to claim 1 or 2, characterized in that the wavelength of the first light beam is greater than the wavelength of the second light beam; Define the line connecting the geometric center of the dichroic mirror (132) and the optical center of the focusing mirror (11) as the first optical axis. The optical axis of the first light beam is offset relative to the first optical axis in the direction in which the second light beam enters the dichroic mirror (132), and the offset distance L1 satisfies the condition: 0.1 mm ≤ L1 ≤ 2 mm.

5. The optical detection system according to claim 1 or 2, characterized in that The second light source assembly (13) is in multiple groups, and all the second light source assemblies (13) are arranged in sequence along the light-emitting direction of the first light beam. And in this direction, the wavelengths of the second light beams emitted by each of the second light source assemblies (13) gradually decrease.

6. The optical detection system according to claim 5, characterized in that Define the line connecting the geometric center of the dichroic mirror (132) and the optical center of the focusing mirror (11) as the first optical axis, and the axis passing through the geometric center of the dichroic mirror (132) and perpendicular to the first optical axis as the second optical axis; Among the second light source assemblies (13) between the second light source assembly (13) farthest from the first light-emitting unit (121) and the first light source assembly (12), the optical axis of the second light beam is offset relative to the second optical axis in the light-emitting direction of the first light beam, and the offset distance L2 satisfies the condition: 0.1 mm ≤ L2 ≤ 2 mm.

7. The optical detection system according to claim 1 or 2, characterized in that The distance between the light homogenizing member (22) and the light guiding member (21) is K1, and 1 mm ≤ K1 ≤ 3 mm.

8. The optical detection system according to claim 1 or 2, characterized in that It further includes a first detection module (30). The first detection module (30) includes a beam splitting detection optical fiber (31) and a plurality of first detection positions (32). The beam splitting end of the beam splitting detection optical fiber (31) has a plurality of beam splitting portions (312), and all the beam splitting portions (312) correspond to all the first detection positions (32) one by one; The beam splitting detection optical fiber (31) is configured to separate the homogenized first detection light beam to the corresponding first detection positions (32) through the respective beam splitting portions (312).

9. The optical detection system according to claim 8, wherein, the beam splitting detection optical fiber (31) is a multi-core optical fiber, the multi-core optical fiber includes a plurality of sub-optical cores (311a), and each of the sub-optical cores (311a) has a relatively arranged sub-combining portion (311b) and a sub-beam splitting portion (311c); at the combining end of the beam splitting detection optical fiber (31), the sub-combining portions (311b) of all the sub-optical cores (311a) form a plurality of layers around; at the beam splitting end of the beam splitting detection optical fiber (31), the sub-beam splitting portions (311c) of all the sub-optical cores (311a) are evenly divided into a plurality of beam splitting portions (312); in each of the beam splitting portions (312), there are sub-beam splitting portions (311c) that are optically connected to the sub-combining portions (311b) of each of the layers.

10. The optical detection system according to claim 8, wherein, the distance between the light homogenizing member (22) and the beam splitting detection optical fiber (31) is K2, and 1 mm ≤ K2 ≤ 3 mm.

11. The optical detection system according to claim 1 or 2, wherein, it further includes a second light source module (40) and a second detection module (50); the second detection module (50) includes a plurality of second detection positions (51), the second light source module (40) is configured to emit a second detection light beam to the second detection positions (51), and the wavelength of the second detection light beam is less than the wavelength of the first detection light beam.

12. The optical detection system according to claim 11, wherein, the second light source module (40) includes a third light source (41), a third filter (42) and a third collimating member (43), the third light source (41) is configured to emit a second detection light beam, the third filter (42) is configured to filter the second detection light beam, and the third collimating member (43) is configured to collimate the second detection light beam.

13. A sample analyzer, wherein, it includes the optical detection system according to any one of claims 1 to 12 above, and the optical detection system is configured to perform optical detection on a sample to be measured.

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