Preparation of dihydroquercetin selenium-added yeast tablet

Abstract

The invention relates to the technical field of yeast tablet processing, in particular to a preparation method of a dihydroquercetin selenium-added yeast tablet, which comprises the following steps: step 1, mixing selenium yeast, dihydroquercetin, corn starch, cane sugar and low-substituted hydroxypropyl cellulose, sieving with a 60-mesh sieve to obtain auxiliary material powder, then checking the weight of the auxiliary material powder by two persons, and finally respectively loading into packaging bags for later use; the preparation method comprises the following steps: 1, preparing a yeast tablet, preparing a 30% ethanol solution, and 2, putting auxiliary material powder into a groove-shaped mixer according to the amount of 40kg per pot. According to the preparation method disclosed by the invention, inflammation, malignant tumor and microbial infection can be resisted by arranging dihydroquercetin, and body inflammation can be reduced in the digestion promoting process of the yeast tablet by adding dihydroquercetin into the yeast tablet; meanwhile, selenium is added into the yeast tablet, so that the dihydroquercetin selenium-added yeast tablet can further strengthen physique and protect heart and cerebral vessels and livers, and in the reproduction process, granular sensation of a finished product is reduced through multiple times of screening, so that the finished product is better in appearance.

Description

Technical Field

[0001] The present application relates to the technical field of yeast tablet processing, and specifically to the preparation of a dihydroquercetin-selenium-added yeast tablet. Background Art

[0002] Yeast tablets are also called mother yeast, which are commonly used in clinical treatment of indigestion. This medicine is rich in B vitamins, amino acids and trace elements chromium. It is a nutritional supplement. Adequate vitamin B2 and B6 can enhance the body's immune function, which is essential for maintaining normal immune function during pregnancy and after the birth of the baby. The niacin in yeast tablets can dilate blood vessels and lower blood lipids, so it is very beneficial to the blood circulation of the fetus and pregnant women. Traditional yeast tablets are usually composed of vitamins B1 and B2, trace elements chromium, niacin and some amino acids. They are mainly used to enhance appetite and supplement nutrition. They are mostly taken by pregnant women and diabetic patients, and their scope of application is relatively small. Therefore, in order to solve the above problems, a preparation method of dihydroquercetin plus selenium yeast tablets is proposed. Summary of the invention

[0003] The purpose of the present application is to provide a preparation method of dihydroquercetin-selenium-added yeast tablets to solve the problem that the application range of yeast tablets is relatively small.

[0004] To achieve the above objectives, this application provides the following technical solutions: A preparation method of a dihydroquercetin-selenium-enriched yeast tablet comprises the following steps: Step 1: Selenium yeast, dihydroquercetin, corn starch, sucrose and low-substituted hydroxypropyl cellulose are mixed and passed through a 60-mesh sieve to obtain auxiliary material powder, and then the auxiliary material powder is weighed and checked by two persons, and finally packed into packaging bags for later use; Step 2: Prepare 30% ethanol solution; Step 3: Put the auxiliary material powder into the trough mixer, close the cover, and mix it through the trough mixer; Step 4: Add 30% ethanol, cover the machine, and stir to make a soft material. The quality of the soft material is based on the condition that it can be squeezed into a ball and falls apart when pressed lightly. Step 5: Install the 18-mesh nylon mesh on the pellet machine. It should be tight and flat. Check the nylon mesh to ensure that there is no damage. Then start the pellet machine and add the soft material into the pellet machine hopper with a stainless steel scoop for pelleting. Step 6: Place the particles in a circulating oven for drying, and take samples to check the particle status at any time during the drying process; Step 7: Granulate the dried granules together with the powdered sugar. After granulation, ensure that the granules have a consistent appearance and fluidity. After granulation, collect the materials in a stainless steel bucket for later use; Step 8: Add the whole granules and magnesium stearate into the mixer, close the feed port, and then start the mixer to mix for 30 minutes. After the granules meet the requirements, take out the granules and weigh them for later use; Step nine: test and adjust the tablet press. After the adjustment is completed, put the granules into the tablet press, start the tablet press to perform tableting, and obtain dihydroquercetin and selenium yeast tablets; Step 10: Screen the prepared dihydroquercetin and selenium yeast tablets to remove all the subdivided particles and granules, and put the qualified tablets into a stainless steel barrel. Then, package the prepared dihydroquercetin and selenium yeast tablets, and collect and treat the waste materials in a unified manner.

[0005] Preferably, the dosage of auxiliary powder in step 1 is 17.5% of selenium yeast, 12.5% ​​of dihydroquercetin, 10% of corn starch, 50% of sucrose and 7.5% of low-substituted hydroxypropyl cellulose.

[0006] Preferably, in step 3, the auxiliary materials in the trough mixer are 40 kg per pot, and the mixing time is 20 minutes.

[0007] Preferably, the stirring time in step 4 is 15 to 20 minutes, at which time the quality of the soft material is such that it can be formed into a ball by lightly holding and can be dispersed by lightly pressing.

[0008] Preferably, in step six, the oven temperature is not higher than 70° C., and the moisture content of the particles is controlled to be between 2.0% and 5.5%.

[0009] Preferably, during debugging in step nine, the tablet friability is controlled to lose weight by no more than 0.8%, and there shall be no breakage, cracking or fragmentation. At the same time, the appearance quality and weight difference of the tablets are checked, requiring no cracks, prying lids, burrs, rough surfaces or sticking, and the weight difference shall not exceed ±5%.

[0010] Compared with the prior art, the beneficial effects of this application are: In the present application, dihydroquercetin can resist inflammation, malignant tumors and microbial infections, and yeast tablets are rich in B vitamins, amino acids and trace elements chromium. Adding dihydroquercetin to yeast tablets can reduce body inflammation and enhance consumer physique in the process of yeast tablets promoting digestion. At the same time, selenium is added to the yeast tablets. Under the effects of selenium on antioxidant, immune regulation, cardiovascular protection and liver protection, dihydroquercetin plus selenium yeast tablets can further enhance physical fitness, protect cardiovascular and cerebrovascular and liver, making it applicable to a wider range of people. In the reproduction process, multiple screenings are used to reduce the granularity of the finished product, making the finished product look better. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 This is a schematic diagram of the formula of the dihydroquercetin plus selenium yeast tablets of this application; Figure 2This is a schematic diagram of the production process of dihydroquercetin plus selenium yeast tablets for this application. DETAILED DESCRIPTION

[0012] See also Figure 1-2 , this application provides a technical solution: A preparation method of a dihydroquercetin-selenium-enriched yeast tablet comprises the following steps: Step 1: 17.5% of selenium yeast, 12.5% ​​of dihydroquercetin, 10% of corn starch, 50% of sucrose and 7.5% of low-substituted hydroxypropyl cellulose are mixed and passed through a 60-mesh sieve to obtain auxiliary material powder, which is then weighed and checked by two persons, and finally packed into packaging bags for later use; Step 2: Prepare 30% ethanol solution; Step 3: Put the auxiliary material powder into the trough mixer according to the amount of 40kg per pot, close the cover, and mix it in the trough mixer for 20 minutes; Step 4: Add 30% ethanol, cover the machine, and stir for 15 to 20 minutes to make a soft material. The quality of the soft material is based on the fact that it can be squeezed into a ball and falls apart when pressed lightly. Step 5: Install the 18-mesh nylon mesh on the pellet machine. It should be tight and flat. Check the nylon mesh to ensure that there is no damage. Then start the pellet machine and add the soft material into the pellet machine hopper with a stainless steel scoop for pelleting. Step 6: Place the pellets in a circulating oven and keep the oven temperature below 70°C for drying. Take samples at any time during the drying process to check the pellet state and control the moisture content of the pellets to be between 2.0% and 5.5%; Step 7: Granulate the dried granules together with the powdered sugar. After granulation, ensure that the granules have a consistent appearance and fluidity. After granulation, collect the materials in a stainless steel bucket for later use; Step 8: Add the whole granules and magnesium stearate into the mixer, close the feed port, and then start the mixer to mix for 30 minutes. After the granules meet the requirements, take out the granules and weigh them for later use; Step 9: Test and adjust the tablet press. After the adjustment is completed, put the granules into the tablet press and start the tablet press to press the tablets. The tablet friability is controlled to reduce the weight loss by no more than 0.8%, and there should be no breakage, cracking or fragmentation. At the same time, check the appearance quality and weight difference of the tablets. It is required that there should be no cracks, prying lids, burrs, pitting, and sticking. The weight difference should not exceed ±5%, and the dihydroquercetin selenium yeast tablets are obtained. Step 10: Screen the prepared dihydroquercetin and selenium yeast tablets to remove all the subdivided particles and granules, and put the qualified tablets into a stainless steel barrel. Then, package the prepared dihydroquercetin and selenium yeast tablets, and collect and treat the waste materials in a unified manner.

[0013] Dihydroquercetin can resist inflammation, malignant tumors and microbial infections, while yeast tablets are rich in B vitamins, amino acids and trace element chromium. Adding dihydroquercetin to yeast tablets can reduce inflammation in the body and enhance consumers' physical fitness in the process of promoting digestion. At the same time, selenium is added to the yeast tablets. Under the effects of selenium's antioxidant, immune regulating, cardiovascular and liver protection, dihydroquercetin plus selenium yeast tablets can further enhance physical fitness and protect cardiovascular and cerebrovascular systems and the liver. During the reproduction process, multiple screenings are used to reduce the granularity of the finished product, making the finished product look better.

[0014] This article uses specific examples to illustrate the principles and implementation methods of this application. The above examples are only used to help understand the method and its core ideas of this application. The above is only the preferred implementation method of this application. It should be pointed out that due to the limitations of textual expression and the objective existence of infinite specific structures, ordinary technicians in this technical field can make several improvements, modifications or changes without departing from the principles of this application, and can also combine the above technical features in an appropriate manner; these improvements, modifications, changes or combinations, or the direct application of the inventive concept and technical solution to other occasions without improvement, should be regarded as the scope of protection of this application.

Claims

1. A preparation method of a dihydroquercetin-selenium-yeast tablet, characterized in that: The following steps are involved: Step 1: Selenium yeast, dihydroquercetin, corn starch, sucrose and low-substituted hydroxypropyl cellulose are mixed and passed through a 60-mesh sieve to obtain auxiliary material powder, and then the auxiliary material powder is weighed and checked by two persons, and finally packed into packaging bags for later use; Step 2: Prepare 30% ethanol solution; Step 3: Put the auxiliary material powder into the trough mixer, close the cover, and mix it through the trough mixer; Step 4: Add 30% ethanol, cover the machine, and stir to make a soft material. The quality of the soft material is based on the condition that it can be squeezed into a ball and falls apart when pressed lightly. Step 5: Install the 18-mesh nylon mesh on the pellet machine. It should be tight and flat. Check the nylon mesh to ensure that there is no damage. Then start the pellet machine and add the soft material into the pellet machine hopper with a stainless steel scoop for pelleting. Step 6: Place the particles in a circulating oven for drying, and take samples to check the particle status at any time during the drying process; Step 7: Granulate the dried granules together with the powdered sugar. After granulation, ensure that the granules have a consistent appearance and fluidity. After granulation, collect the materials in a stainless steel bucket for later use; Step 8: Add the whole granules and magnesium stearate into the mixer, close the feed port, and then start the mixer to mix for 30 minutes. After the granules meet the requirements, take out the granules and weigh them for later use; Step nine: test and adjust the tablet press. After the adjustment is completed, put the granules into the tablet press, start the tablet press to perform tableting, and obtain dihydroquercetin and selenium yeast tablets; Step 10: Screen the prepared dihydroquercetin and selenium yeast tablets to remove all the subdivided particles and granules, and put the qualified tablets into a stainless steel barrel. Then, package the prepared dihydroquercetin and selenium yeast tablets, and collect and treat the waste materials in a unified manner.

2. The preparation method of a dihydroquercetin-selenium-enriched yeast tablet according to claim 1, characterized in that: The dosage of auxiliary powder in step 1 is 17.5% of selenium yeast, 12.5% ​​of dihydroquercetin, 10% of corn starch, 50% of sucrose and 7.5% of low-substituted hydroxypropyl cellulose.

3. The preparation method of a dihydroquercetin-selenium-enriched yeast tablet according to claim 1, characterized in that: In step 3, the auxiliary materials in the trough mixer are 40 kg per pot, and the mixing time is 20 minutes.

4. The preparation method of a dihydroquercetin-selenium-yeast tablet according to claim 1, characterized in that: The stirring time in step 4 is 15 to 20 minutes. At this time, the quality of the soft material is such that it can be formed into a ball when lightly squeezed and will fall apart when lightly pressed.

5. The preparation method of a dihydroquercetin-selenium-yeast tablet according to claim 1, characterized in that: In step six, the oven temperature is not higher than 70° C., and the moisture content of the particles is controlled to be between 2.0% and 5.5%.

6. The preparation method of a dihydroquercetin-selenium-yeast tablet according to claim 1, characterized in that: During debugging in step nine, control the tablet friability to a weight loss of no more than 0.8%, and there must be no breakage, cracking or fragmentation. At the same time, check the tablet's appearance quality and weight difference. There must be no splits, prying lids, burrs, rough surfaces, or sticking. The weight difference must not exceed ±5%.

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