Animal serum sample separation and collection device and method

By designing an animal serum sample separation and collection device, batch jetting of serum in the syringe is achieved using support frames and down-pressure frames, and combining positioning frames and contact limit sensors to realize batch quantitative separation and collection, solving the problems of low efficiency and increased consumables in the prior art, improving collection efficiency and reducing workload.

CN120094249APending Publication Date: 2025-06-06崇左市水产畜牧技术服务中心
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Patent Information

Application Number
CN202510171057.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-02-17
Publication Date
2025-06-06

AI Technical Summary

Technical Problem

The prior art has low efficiency and high workload in the collection and separation of animal serum samples, and requires technical personnel to have strong skills to control the stability and amount of dumping, which can easily lead to misoperation and increase in consumables.

Method used

An animal serum sample separation and collection device was designed. By setting up a support frame and a down-pressure bracket, the serum in the syringe is batch sprayed into the EP tube, improving efficiency, reducing consumables, and batch quantitative separation and collection is achieved through positioning brackets and contact limit sensors.

Benefits of technology

It realizes batch separation and collection of serum samples, improves efficiency, reduces workload, and reduces consumables, and has high application promotion value.

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Abstract

The invention belongs to the technical field of animal serum sample collection, and discloses an animal serum sample separation and collection device and method. The supporting frame comprises a first rectangular bottom plate, a second rectangular bottom plate and four supporting columns, the four supporting columns are perpendicularly and fixedly arranged at the four corners of the upper surface of the first bottom plate correspondingly to define a rectangular frame structure, and a plurality of push rods are perpendicularly arranged on the upper surface of the first bottom plate; the first bottom plate can turn over relative to the second bottom plate; the downward pressing support is located above the first bottom plate and can be connected in a sliding mode in the axial direction of the four supporting columns; a gland is arranged in the middle of each second supporting rod of the pressing support, a through hole is formed in the center of each gland in a penetrating mode, and a through hole for the connecting part to penetrate through is formed in the center of each gland in a penetrating mode. Pipe clamps are arranged on the pressing support, the pipe clamps and the push rods are in one-to-one correspondence with the glands, and the push rods coincide with the center axes of the through holes of the corresponding glands. The serum separating and collecting device can separate and collect serum in batches, improve efficiency, reduce workload and reduce consumables.
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Description

Technical Field

[0001] The present invention relates to the technical field of animal serum sample collection, and more specifically, to an animal serum sample separation and collection device and method. Background Art

[0002] Animal serum testing is one of the commonly used auxiliary inspection methods in the process of animal field epidemiological investigation. It can be used to perform biochemical, immune, and hormone tests. When extracting animal serum, the existing technology usually uses a blood collector dedicated to animal husbandry to collect blood from animals, centrifuge and precipitate, and then pour the upper layer of serum into an EP tube or drain it into an EP tube with a diversion tube. The existing technology blood collector (such as Figure 8 As shown in the figure, it includes a syringe 24, a piston 23, a core rod 37, and a needle 38. The piston 23 can be slidably sealed and arranged in the syringe 24. The lower end of the piston 23 is detachably connected to one end of the core rod 37, and the other end of the core rod 37 passes through the through hole at the bottom end of the syringe 24. The connecting part at the top end of the syringe 24 is detachably connected to the needle 38, and scale lines are arranged on the side wall of the syringe 24.

[0003] In order to better investigate and prevent animal diseases, animal serum testing requires sampling and testing of a certain batch. For example, if there are more than 100 pigs in a farm, technicians need to randomly collect blood samples from dozens of pigs to obtain a batch of pig blood samples (one syringe per pig), and then transport the batch of blood samples to the laboratory and centrifuge them under the action of a centrifuge to separate them into layers, and collect the upper serum one tube at a time. Although the existing blood collector can be easily transported to the laboratory by removing the needle and the core rod of the syringe 24, it can be directly placed in the centrifuge for centrifugation. The blood clots or blood cell sediments of the blood sample after centrifugation and separation are condensed at the bottom of the syringe of the blood collector, and the serum is precipitated (such as Fig. 9 , Fig.10 However, for serum testing, technicians are required to pour the serum in the syringes of batch blood collectors into the EP tubes one by one according to the prescribed amount, which is a large workload and requires strong skills of the technicians to control the pouring stability, tilt angle and pouring amount, and has low efficiency. When the sampling end cover at the upper end of the syringe is opened, the serum is easily spilled and the pouring amount is difficult to control. Although the use of a guide tube for drainage can avoid the defect of dumping, it increases consumables and is in urgent need of improvement. Summary of the invention

[0004] One object of the present invention is to provide an animal serum sample separation and collection device, which supports batches of syringes after centrifugal stratification by arranging a support frame, squeezes the batches of syringes along the axial direction of the syringes by pressing the support frame down, so that the connecting part at the top of the syringe passes through the through hole of the corresponding gland, and the lower surface of the gland of the pressing support frame abuts against the syringe sampling end cover, so as to further support and fix the syringe batches, and makes the syringes on the first bottom plate horizontal or tilted downward by flipping the first bottom plate relative to the second bottom plate by 90°~135°, and then controls the pressing support frame to squeeze the batches of syringes along the axial direction of the syringe, so as to facilitate the serum in the syringe to be sprayed from the connecting part into the EP tube on the pressing support frame, which can not only separate and collect serum in batches, improve efficiency, reduce workload, but also reduce consumables, and has high application and promotion value.

[0005] In order to achieve these purposes and other advantages according to the present invention, the present invention provides an animal serum sample separation and collection device, which includes a blood collector, the top end of the syringe of the blood collector is provided with a connecting portion that passes through the syringe, and also includes: A support frame, comprising a rectangular first bottom plate, a rectangular second bottom plate and four pillars, the four pillars are respectively and vertically fixed at four corners of the upper surface of the first bottom plate, so that the four pillars surround a rectangular frame structure on the first bottom plate, a plurality of push rods adapted to the through holes at the bottom end of the syringe of the blood collector are vertically arranged on the upper surface of the first bottom plate, the push rods are used to penetrate the through holes at the bottom end of the syringe and the upper end surfaces of the push rods are pressed against the central groove at the bottom of the piston in the syringe, one side of the first bottom plate is hinged to one side of the second bottom plate, and the first bottom plate can be flipped relative to the second bottom plate by 0°~135° around the hinge shaft above the second bottom plate; a driving member for driving the first bottom plate to flip is arranged on the opposite side where the first bottom plate and the second bottom plate are hinged; A downward pressing bracket, which is located above the first bottom plate and can be slidably connected along the axial direction of the four pillars; the downward pressing bracket includes two second cross bars, a plurality of pressure covers and a plurality of second support rods, the two second cross bars are respectively arranged on opposite sides of the rectangular frame structure, the plurality of second support rods are parallel to each other and span between the two second cross bars in the same plane, one or two pressure covers are arranged in the middle of each second support rod, a through hole is penetrated in the center of the pressure cover, the aperture of the through hole is greater than or equal to the root outer diameter of the top connecting part of the syringe, and smaller than the inner diameter of the syringe, and the through hole is used to supply pressure directly below the pressure cover The top connecting part of the syringe passes through; the second support rod or the upper surface of the gland is provided with a tube clamp for clamping the EP tube, the central axis of the tube clamp and the central axis of the through hole of the gland are in the same plane, and the plane is perpendicular to the hinge shaft, the angle between the extension line of the central axis of the tube clamp and the gland is 10°~45°, so that when the tube clamp clamps the EP tube, the opening of the EP tube is tilted and covered above the through hole in a vertical state, the tube clamp is arranged close to the hinge shaft side, each of the tube clamps and each of the push rods corresponds to each of the glands one by one, and the push rods coincide with the central axis of the through hole of the corresponding gland.

[0006] Preferably, the pressing down bracket can be connected in an axial sliding manner along the four pillars as follows: two second cross bars are parallel to each other and in the same plane as the first base plate, a square second slider is fixed at both ends of each second cross bar, and a second slide groove matching the second slider is provided on the opposite sides of the two pillars on the corresponding sides of the rectangular frame structure; it also includes a driving mechanism for driving the pressing down bracket to slide axially along the four pillars, the driving mechanism includes a ball screw and a stepper motor, the ball screw is arranged in the second slide groove along the axial direction of the pillar, one end of the ball screw is rotatably connected to the upper wall of the second slide groove through a bearing, and the other end is connected to the output end of the stepper motor, the stepper motor base is fixedly connected to the first base plate, and the second slider is fixedly connected to the nut of the ball screw.

[0007] Preferably, the through hole of the gland is a tapered through hole that is larger at the bottom and smaller at the top, the inner diameter of the upper opening of the tapered through hole is equal to or slightly larger than the outer diameter of the root of the top connection of the syringe, and the inner diameter of the lower opening of the tapered through hole is equal to or slightly larger than the inner diameter of the syringe.

[0008] Preferably, it also includes a positioning bracket, which is located between the pressing down bracket and the first bottom plate and can be slidably connected along the axial direction of the four pillars, and the positioning bracket, the pressing down bracket and the first bottom plate are parallel to each other; the positioning bracket includes two first cross bars, a plurality of spacer bars and a first support rod, the two first cross bars are respectively arranged on the other opposite sides of the rectangular frame structure, the first support rod spans between the two first cross bars, the plurality of spacer bars are respectively equidistant and vertically arranged on one side or both sides of the first support rod, the plurality of spacer bars are parallel to each other and are in the same plane as the first support rod and the first cross bar, the distance between two adjacent spacer bars is equal to or slightly larger than the outer diameter of the syringe, the rectangular space between two adjacent spacer bars corresponds one to one with each of the pressure caps, and the rectangular median line of the rectangular space intersects perpendicularly with the central axis of the corresponding pressure cap through hole, and the rectangular median line is parallel to the spacer bars.

[0009] Preferably, the positioning bracket can be slidably connected along the axial direction of the four pillars as follows: the two first cross bars are parallel to each other and the plane in the same plane is parallel to the first bottom plate, a square first slider is fixed at both ends of each first cross bar, and first slide grooves matching the first slider are opened on the opposite side surfaces of the two pillars on the corresponding sides of the rectangular frame structure; a locking mechanism for clamping and releasing the first slider is arranged on the pillar where the first slide groove is opened; the locking mechanism includes a plurality of limiting holes and a plurality of limiting bolts, the plurality of limiting holes are arranged in sequence along the axial direction of the pillars of the first slide groove, the plurality of limiting holes all pass through the side walls of the first slide groove, the plurality of limiting bolts are correspondingly screwed to the plurality of limiting holes, and can pass through the side walls of the first slide groove to press against the first slider.

[0010] Preferably, it also includes a contact limit sensor and a controller, wherein the contact limit sensor is arranged on the upper surface of the first support rod of the positioning bracket and is located directly below the second support rod, and the contact limit sensor and the stepper motor are electrically connected to the controller.

[0011] Preferably, the two second cross bars are located on the long side frames of the rectangular frame structure on both sides, and the two first cross bars are located on the wide side frames of the rectangular frame structure on both sides.

[0012] Preferably, the plurality of glands and the plurality of spacers are made of transparent material, the lower edge of the gland is provided with a conspicuous edge line, and the upper edge of the spacer is provided with a conspicuous edge line. Preferably, it also includes two support members, which are respectively arranged on the outside of two pillars close to the hinge shaft side, each of the support members includes two third sliders, a triangular prism body and two third sliding grooves, the two bottom surfaces of the triangular prism body are right-angled triangle bottom surfaces, the edges of the triangular prism body are transitioned into arc surfaces on two adjacent side surfaces, the side of the triangular prism body is provided with a rubber layer, the two third sliding grooves are provided on the oblique side surface of the triangular prism body, and the two third sliding grooves are parallel to the oblique sides, the two third sliders are respectively slidably matched and connected with the two third sliding grooves, the two third sliders are commonly provided with a rotating shaft, the rotating shaft can rotate relative to the third slider, and the two ends of the rotating shaft are fixedly connected to the outer upper ends of the pillars.

[0013] The present invention also discloses a method for separating and collecting animal serum samples, which uses the above-mentioned animal serum sample separation and collection device to separate and collect animal serum samples in batches from animal blood samples that are centrifuged to separate serum in batches.

[0014] The present invention has at least the following beneficial effects: First, the present invention supports batches of syringes after centrifugal stratification by providing a support frame, and squeezes batches of syringes along the axial direction of the syringes through the downward pressing support, so that the connecting part at the top of the syringe passes through the through hole of the corresponding gland, and the lower surface of the gland of the downward pressing support contacts with the syringe sampling end cover, so as to further support and fix the syringe batches, and the first bottom plate is flipped 90°~135° relative to the second bottom plate, so that the syringes on the first bottom plate are horizontal or tilted downward, and then the downward pressing support is controlled to squeeze the batches of syringes along the axial direction of the syringe, which is conducive to the serum in the syringe being sprayed from the connecting part into the EP tube on the downward pressing support, which can not only collect serum in batches, improve efficiency, reduce workload, but also reduce consumables, and has high application and promotion value.

[0015] Second, the positioning bracket designed in the present invention has a guiding function and can limit the moving distance of the downward-pressing bracket toward the syringe, control the extrusion amount, realize batch quantitative separation and collection, and meet the needs of collecting multiple items for testing, effectively improving the efficiency of separating and collecting serum.

[0016] Third, the present invention provides conspicuous edge lines on the lower edge of the pressure cover and the upper edge of the spacer strip, which is conducive to observation, control and adjustment of batch quantitative collection.

[0017] Fourthly, the support member designed in the present invention provides buffering and supporting functions for the support frame during the flipping process, thereby laying a stable foundation for the flipping operation and the collection process.

[0018] Other advantages, objectives and features of the present invention will be embodied in part through the following description, and in part will be understood by those skilled in the art through study and practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the three-dimensional structure of one implementation form of the animal serum sample separation and collection device of the present invention; Figure 2 It is a schematic diagram of the internal structure of a front view of an implementation form of the animal serum sample separation and collection device of the present invention in which a syringe is placed; Figure 3 It is a schematic diagram of the internal structure of a main view of an implementation form of the animal serum sample separation and collection device of the present invention; Figure 4 A schematic diagram of the internal structure of a device for separating and collecting animal serum samples according to the present invention, viewed from above; Figure 5 It is a schematic structural diagram of the animal serum sample separation and collection device of the present invention when the syringe on the first bottom plate is turned horizontally; Figure 6 It is a schematic structural diagram of the animal serum sample separation and collection device of the present invention when the syringe on the first bottom plate is turned over and tilted downward; Figure 7 A schematic diagram of the internal structure of another embodiment of the animal serum sample separation and collection device of the present invention from above; Figure 8 A schematic diagram of the structure of a blood sampling device specially used for blood sampling of livestock is provided in the prior art; Fig. 9 A diagram showing the centrifugal stratification of a needle barrel of a blood collection device in the prior art; Fig.10 This is a diagram showing the prior art of the blood collection device with the serum in the syringe pouring downwards; Among them, the first base plate 1; the second base plate 2; the limit hole 3; the limit bolt 4; the pillar 5; the first slide 6; the first cross bar 7; the spacer 8; the contact limit sensor 9; the first support rod 10; the second cross bar 11; the second support rod 12; the pressure cover 13; the through hole 14; the second slide 15; the stepping motor 16; the second slider 17; the ball screw 18; the first slider 19; the connecting part 20; the serum 21; the blood clot or the blood cell sediment 22; the piston 23; the syringe 24; the push rod 25; the pressing bracket 26; the positioning bracket 27; the tube clamp 28; the EP tube 29; the third slider 30; the triangular prism body 31; the third slide 32; the support member 33; the hinge shaft 34; the electric telescopic rod 35; the laboratory table 36; the core rod 37; the needle 38. DETAILED DESCRIPTION

[0021] The present invention is further described in detail below in conjunction with the accompanying drawings and specific embodiments so that those skilled in the art can implement the invention with reference to the description.

[0022] It should be understood that the terms such as “having”, “including” and “comprising” used herein do not exclude the existence or addition of one or more other elements or combinations thereof.

[0023] It should be noted that the experimental methods described in the following embodiments are conventional methods unless otherwise specified, and the structures and components can be obtained from commercial sources unless otherwise specified; in the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "set" should be understood in a broad sense, for example, they can be fixedly connected, set, or detachably connected, set, or connected and set in one piece. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood in specific circumstances. The orientation or position relationship indicated by the terms "lateral", "longitudinal", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc. is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention.

[0024] Figures 1 to 6 The embodiment of the animal serum sample separation and collection device is shown, which includes: a blood collector, a connection portion 20 penetrating the syringe 24 is provided at the top of the syringe 24, and further includes: A support frame, comprising a rectangular first bottom plate 1, a rectangular second bottom plate 2 and four pillars 5, the four pillars 5 are respectively fixedly arranged vertically at the four corners of the upper surface of the first bottom plate 1, so that the four pillars 5 are surrounded by a rectangular frame structure on the first bottom plate 1, a plurality of push rods 25 adapted to the through hole at the bottom end of the syringe 24 of the blood collector are vertically arranged on the upper surface of the first bottom plate 1, the push rods 25 are used to penetrate the through hole at the bottom end of the syringe 24 and the upper end surface of the push rods 25 is pressed against the central groove at the bottom of the piston 23 in the syringe 24, one side of the first bottom plate 1 is hinged to one side of the second bottom plate 2, the first bottom plate 1 can be flipped relative to the second bottom plate 2 by 0°~135° around the hinge shaft 34 above the second bottom plate 2; a driving member for driving the first bottom plate 1 to flip is arranged on the opposite side where the first bottom plate 1 and the second bottom plate 2 are hinged; A downward pressing bracket 26 is located above the first bottom plate 1 and can be slidably connected along the axial direction of the four pillars 5; the downward pressing bracket 26 includes two second cross bars 11, a plurality of pressure covers 13 and a plurality of second support rods 12, the two second cross bars 11 are respectively arranged on opposite sides of the rectangular frame structure, the plurality of second support rods 12 are parallel to each other and span between the two second cross bars 11 in the same plane, one or two pressure covers 13 are arranged in the middle of each second support rod 12, a through hole 14 is penetrated in the center of the pressure cover 13, the aperture of the through hole 14 is greater than or equal to the root outer diameter of the top connecting part 20 of the syringe 24, and is smaller than the inner diameter of the syringe 24, and the through hole 14 is used to provide pressure to the top of the syringe 24 directly below the pressure cover 13 The end connection part 20 passes through; the upper surface of the second support rod 12 or the pressure cover 13 is provided with a tube clamp 28 for clamping the EP tube 29, the central axis of the tube clamp 28 and the central axis of the through hole 14 of the pressure cover 13 are in the same plane, and the plane is perpendicular to the hinge shaft 34, the angle between the extension line of the central axis of the tube clamp 28 and the pressure cover 13 is 10°~45°, so that when the tube clamp 28 clamps the EP tube 29, the opening of the EP tube 29 is inclined to cover above the through hole 14 in a vertical state, and the tube clamp 28 is arranged near the hinge shaft 34 side, each of the tube clamps 28 and each of the push rods 25 corresponds to each of the pressure covers 13 one by one, and the push rods 25 coincide with the central axis of the through hole 14 of the corresponding pressure cover 13.

[0025] When in use, when the through hole at the bottom end of the syringe 24 of the blood collector is penetrated by the push rod 25, and the upper end surface of the push rod 25 presses against the central groove at the bottom of the piston 23 in the syringe 24, the central axis of the through hole 14 of the gland 13 and the central axis of the syringe 24 coincide with the central axis of the push rod 25, and the pressing bracket 26 is controlled to approach the syringe 24 along the axial direction of the four pillars 5, so that the connecting portion 20 at the top end of the syringe 24 can pass through the through hole 14 of the corresponding gland 13, and when the lower surface of the gland 13 of the pressing bracket 26 contacts the top end of the syringe 24, the pressing bracket 26 reaches the set position, which further supports and fixes the batch of syringes 24; then, the first bottom plate 1 is driven on the second bottom plate 2 by the driving member. The syringes 24 and the EP tubes 29 on the tube clamps 28 are synchronously flipped at a preset angle relative to the second bottom plate 2, so that the syringes 24 on the first bottom plate 1 are horizontally or tilted downward, and the EP tubes 29 are opened upward, and then the downward pressure bracket 26 is controlled to continue to move toward the syringe 24 along the axial direction of the four pillars 5, and pressure is applied to the syringe 24 along the axial direction of the push rod 25, so that the push rod 25 pushes the piston 23 to move toward the top of the syringe 24 by a preset displacement, so that the serum in the syringe 24 can be sprayed out from the through hole of the connecting part 20 of the syringe 24, and is received by the EP tube 29 clamped on the downward pressure bracket 26, so as to realize batch collection and improve efficiency, without consuming a guide tube and reducing consumables.

[0026] In the above technical solution, the animal serum sample separation and collection device includes a blood collector, a support frame and a downward support 26. The top of the syringe 24 of the blood collector is provided with a connecting portion 20 that passes through the syringe 24. The blood collector can adopt an existing blood collector dedicated to animal husbandry blood collection, such as Figure 8 As shown, the blood collector includes a syringe 24, a piston 23, a core rod 37, and a needle 38. The piston 23 can be slidably sealed and arranged in the syringe 24. The central groove at the bottom of the piston 23 can be detachably connected to one end of the core rod 37. The other end of the core rod 37 passes through the through hole at the bottom of the syringe 24. There are scale lines on the side wall of the syringe 24. The connecting part 20 at the top of the syringe 24 is a conical tube structure or a cylindrical structure with a larger bottom and a smaller top. When blood is collected, the connecting part 20 is connected to the needle 38. When collecting serum, the needle 38 is removed; The support frame includes a rectangular first bottom plate 1, a rectangular second bottom plate 2 and four pillars 5. The four pillars 5 are respectively fixed vertically at the four corners of the upper surface of the first bottom plate 1, so that the four pillars 5 surround a rectangular frame structure on the first bottom plate 1. A plurality of push rods 25 adapted to the through holes at the bottom end of the syringe 24 of the blood collector are vertically arranged on the upper surface of the first bottom plate 1. The push rods 25 are used to penetrate the through holes at the bottom end of the syringe 24 and the upper end surface of the push rods 25 is pressed against the central groove at the bottom of the piston 23 in the syringe 24. When in use, the push rod 25 can slide into the syringe 24 through the through holes at the bottom end of the syringe 24, and the upper end surface of the push rod 25 can be pressed against the central groove at the bottom of the piston 23 in the syringe 24; the second bottom plate 21 is provided with a plurality of push rods 25 adapted to the through holes at the bottom end of the syringe 24 and the upper end surface of the push rods 25 can be pressed against the central groove at the bottom of the piston 23 in the syringe 24. A bottom plate 1 is located above a second bottom plate 2, one side of the first bottom plate 1 is hinged to one side of the second bottom plate 2, the first bottom plate 1 can be flipped 0°~135° relative to the second bottom plate 2 around a hinge shaft 34 above the second bottom plate 2, the hinged parts can be realized by hinge connection, for example, one leaf of a pair of hinges is installed on the end surface of one side of the first bottom plate 1, and the other leaf is installed on the end surface of one side of the second bottom plate 2, the hinge shaft 34 is parallel to the hinged side of the first bottom plate 1 and the second bottom plate 2, so that the first bottom plate 1 can be flipped 0°~135° relative to the second bottom plate 2, and other hinged parts can also be used to realize it; a driving member for driving the first bottom plate 1 to flip is provided on the opposite side where the first bottom plate 1 and the second bottom plate 2 are hinged; A downward pressing bracket 26, which is located above the first bottom plate 1 and can be slidably connected along the axial direction of the four pillars 5; the downward pressing bracket 26 includes two second cross bars 11, a plurality of pressure covers 13 and a plurality of second support rods 12, the two second cross bars 11 are respectively arranged on opposite sides of the rectangular frame structure, the plurality of second support rods 12 are parallel to each other and span between the two second cross bars 11 in the same plane, one or two pressure covers 13 are arranged in the middle of each second support rod 12, a through hole 14 is penetrated in the center of the pressure cover 13, the aperture of the through hole 14 is greater than or equal to the root outer diameter of the top connecting part 20 of the syringe 24, and is smaller than the inner diameter of the syringe 24, and the through hole 14 is used for the top connecting part 20 of the syringe 24 directly below the pressure cover 13 to pass through; the upper surface of the second support rod 12 or the pressure cover 13 is provided with A tube clamp 28 for clamping the EP tube 29 is provided. The tube clamp 28 can be an elastic U-shaped tube clamp, a tiger's mouth tube clamp, an arc-shaped tube clamp, or other tube clamps 28 that are conducive to clamping and removing the EP tube. The central axis of the tube clamp 28 is in the same plane as the central axis of the through hole 14 of the gland 13, and the plane is perpendicular to the hinge shaft 34. The angle between the extension line of the central axis of the tube clamp 28 and the gland 13 is 10°~45°, so that when the tube clamp 28 clamps the EP tube 29, the opening of the EP tube 29 is inclined to cover the through hole 14 in a vertical state. The tube clamp 28 is located near the hinge shaft 34. Each tube clamp 28 and each push rod 25 correspond to each gland 13 one by one, and the push rod 25 coincides with the central axis of the through hole 14 of the corresponding gland 13.

[0027] When in use, the technician first collects blood on site, connects the connection part 20 of the blood collection device syringe 24 with the needle 38, and after the batch blood collection is completed, the syringe 24 with the needle 38 and the core rod 37 removed is placed in the centrifuge for batch centrifugation. The blood sample in the syringe 24 of the blood collection device is centrifuged and layered by the centrifuge, and the blood clot or blood cell sediment 22 coagulates at the bottom of the syringe 24, and the serum 21 precipitates on the upper layer. After the centrifugation is completed, the second bottom plate 2 of the separation and collection device is fixed on the laboratory table 36, the first bottom plate 1 is overlapped on the second bottom plate 2 (at this time, the angle between the first bottom plate 1 and the second bottom plate 2 is 0°), and the lower support 26 is slid upward to a preset height, which is the first set height for placing the syringe 24 in the support frame. The first set height is greater than the height of the push rod 25 plus the height of the syringe 24. Then, the batch of centrifuged and layered blood collection syringes 24 are taken out of the centrifuge without removing the sampling end cap at the upper end of the syringe 24. The batch of syringes 24 are directly inserted into the push rods 25 through the through holes at the bottom ends thereof, and the upper end surfaces of the push rods 25 are pressed against the central groove at the bottom of the piston 23 in the syringe 24. Then, the pressing bracket 26 is controlled to approach the syringe 24 along the axial direction of the four pillars 5, so that the connecting portion 20 at the top of the syringe 24 passes through the through hole 14 of the corresponding pressing cap 13, and when the lower surface of the pressing cap 13 of the pressing bracket 26 contacts the sampling end cap of the syringe 24, the pressing bracket 26 reaches the second set height, and the pressing bracket 26 is controlled to remain motionless, so as to achieve batch support for the syringes 24. Then, the tube clamp 28 on each gland 13 through which the syringe 24 connection part 20 is penetrated clamps the EP tube 29 with the corresponding number, and each EP tube 29 corresponds to each syringe 24, and the opening of the EP tube 29 is tilted and covered above the through hole 14 in the vertical state and above the upper port of the syringe 24 connection part 20, see Figure 3 As shown; then, the driving member drives the first bottom plate 1 to flip over the second bottom plate 2 at a preset angle above the second bottom plate 2, and the batch of syringes 24 and the batch of EP tubes 29 on the tube clamp 28 are flipped synchronously, so that the syringes 24 on the first bottom plate 1 are horizontally or tilted downward, and the EP tubes 29 are opened upward. After maintaining a stable state, the downward pressure bracket 26 is controlled to continue to move toward the syringe 24 along the axial direction of the four pillars 5, and pressure is applied to the syringe 24 along the axial direction of the push rod 25, so that the push rod 25 pushes the piston 23 to move toward the top of the syringe 24 by a preset displacement, so that the serum in the syringe 24 can be sprayed out from the through hole of the connecting part 20 of the syringe 24, and is received by the EP tube 29 clamped on the downward pressure bracket 26, so as to realize batch collection, improve efficiency, and do not consume a guide tube, reducing consumables.

[0028] On the basis of the above implementation, the driving member includes an electric telescopic rod 35, the base of the electric telescopic rod 35 is hinged to the second base plate 2, and the telescopic end of the electric telescopic rod 35 is hinged to the first base plate 1. By controlling the telescopic length of the electric telescopic rod 35, the first base plate 1 can be flipped 0°~135° relative to the second base plate 2 and the first base plate 1 and the second base plate 2 can be kept at an angle of 90°~135° to remain stable. The preset flip angle is used to control the serum in the syringe 24 to spray from the through hole of the syringe 24 connecting part 20 to the EP tube 29 at this position, so as to realize batch collection, improve efficiency and reduce consumables.

[0029] On the basis of the above implementation method, the pressing bracket 26 can be slidably connected along the axial direction of the four pillars 5 as follows: the two second cross bars 11 are parallel to each other and are parallel to the first base plate 1 in the same plane, and square second sliders 17 are fixed at both ends of each second cross bar 11, and second slide grooves 15 matching the second sliders 17 are provided on the opposite sides of the two pillars 5 on the corresponding sides of the rectangular frame structure; so that the two second cross bars 11 that are parallel to each other and on the same plane can slide synchronously along the axial direction of the four pillars 5, thereby driving the multiple pressure covers 13 of the pressing bracket 26 to slide synchronously along the axial direction of the four pillars 5, and realizing the control of the multiple pressure covers 13 to move away from, approach, and push the top ends of the batch syringes 24 inserted on the support frame, so as to realize the batch separation and collection of serum samples. It also includes a driving mechanism for driving the pressing bracket 26 to slide along the axial direction of the four pillars 5, the driving mechanism includes a ball screw 18 and a stepper motor 16, the ball screw 18 is arranged in the second slide groove 15 along the axial direction of the pillar 5, one end of the ball screw 18 is rotatably connected to the upper wall of the second slide groove 15 through a bearing, and the other end is connected to the output end of the stepper motor 16, the base of the stepper motor 16 is fixedly connected to the first base plate 1, and the second slider 17 is fixedly connected to the nut of the ball screw 18. According to needs, a ball screw 18 and a stepper motor 16 can be correspondingly set for each second slider 17 for control, or a ball screw 18 and a corresponding stepper motor 16 can be set for one, two or three of the four second sliders 17 for control, both of which can realize the control of the sliding distance of the pressing bracket 26, and both belong to the protection scope of the present invention.

[0030] The upper end of the syringe 24 of the blood collector is detachably equipped with a sampling end cap, and the connecting portion 20 and the sampling end cap are integrally formed. When blood is collected, the connecting portion 20 is connected to the needle 38 to facilitate blood collection. The sampling end cap and the upper end of the syringe 24 are arranged in a detachable manner, which can facilitate the removal of the sampling end cap as needed to meet other needs. For example, in the prior art, the serum in the syringe 24 can be poured out by removing the sampling end cap.

[0031] Based on the above implementation, the through hole 14 of the gland 13 is a tapered through hole that is larger at the bottom and smaller at the top. The inner diameter of the upper opening of the tapered through hole is equal to or slightly larger than the root outer diameter of the connection part 20 at the top end of the syringe barrel 24, and the inner diameter of the lower opening of the tapered through hole is equal to or slightly larger than the inner diameter of the syringe barrel 24, so that the tapered through hole of the gland 13 is properly matched with the tapered sampling end cap, or properly matched with the tapered top end of the syringe barrel 24.

[0032] Based on the above implementation, the positioning bracket 27 is located between the lower pressing bracket 26 and the first bottom plate 1, and can be slidably connected along the axial direction of the four support columns 5. The positioning bracket 27, the lower pressing bracket 26 and the first bottom plate 1 are parallel to each other; the positioning bracket 27 includes two first cross bars 7, a plurality of spacer bars 8 and a first support rod 10. The two first cross bars 7 are respectively arranged on the other two opposite sides of the rectangular frame structure. The first support rod 10 spans between the two first cross bars 7. The plurality of spacer bars 8 are respectively arranged at equal intervals and perpendicular to one side or both sides of the first support rod 10. The plurality of spacer bars 8 are parallel to each other and are in the same plane as the first support rod 10 and the first cross bars 7. The distance between two adjacent spacer bars 8 is equal to or slightly larger than the outer diameter of the syringe barrel 24. The rectangular space between two adjacent spacer bars 8 corresponds to each gland 13 one by one, and the rectangular median line of the rectangular space is perpendicular to the central axis of the through hole 14 of the corresponding gland 13. The rectangular median line is parallel to the spacer bars 8. This design has a rectangular space in the shape of "匚" formed by two adjacent spacer bars 8 and the first support rod 10 with one side open, which is conducive to placing the syringe barrel 24 at the position corresponding to the push rod 25 and the gland 13 one by one. The design of the positioning bracket 27 not only has a guiding effect, but also can limit the moving distance of the lower pressing bracket 26 towards the syringe barrel 24, control the extrusion amount, realize batch quantitative collection, and effectively improve the efficiency of separating and collecting serum. For the convenience of showing individual structures, Figures 1 to 6 The rectangular space shown between two adjacent spacer bars 8 is such that one gland 13 and one push rod 25 are shown corresponding to every other rectangular space. The structure shown in this view can also achieve the effect of batch separation and collection, but the number of batch collection positions is relatively small. As Figure 7 One implementation form shown is that the rectangular space between two adjacent spacer bars 8 corresponds to each gland 13 one by one, and is arranged on both sides of the first support rod 10, increasing the number of batch collection positions and further improving the batch collection effect.

[0033] On the basis of the above implementation, the positioning bracket 27 can be slidably connected along the axial direction of the four pillars 5 as follows: the two first cross bars 7 are parallel to each other and parallel to the first base plate 1 in the same plane, and a square first slider 19 is fixedly provided at both ends of each first cross bar 7, and a first slide groove 6 matching the first slider 19 is provided on the opposite sides of the two pillars 5 on the corresponding side of the rectangular frame structure; a locking mechanism for clamping and releasing the first slider 19 is provided on the pillar 5 with the first slide groove 6, and the locking mechanism is used to lock and unlock the positioning bracket 27. When the locking mechanism clamps the first slider 19, the positioning bracket 27 can The positioning bracket 27 is locked in a preset position and does not slide. When the locking mechanism releases the first slider 19, the positioning bracket 27 can slide along the axial direction of the pillar 5 to adjust the height of the positioning bracket 27 as needed. In this design, two first cross bars 7 that are parallel to each other and on the same plane slide synchronously along the axial direction of the four pillars 5, thereby driving the multiple rectangular spaces of the positioning bracket 27 to slide synchronously along the axial direction of the four pillars 5. By locking the positioning bracket 27 at a preset height, it is convenient to control the displacement of the pressing bracket 26 toward the syringe 24, control the extrusion amount, and realize the control of the multiple glands 13 to achieve batch quantitative separation and collection of serum samples in the batch syringes 24 inserted on the support frame. The locking mechanism includes multiple limiting holes 3 and multiple limiting bolts 4. The multiple limiting holes 3 are arranged in sequence along the axial direction of the pillar 5 of the first slide 6. The multiple limiting holes 3 all penetrate the side wall of the first slide 6. The multiple limiting bolts 4 are correspondingly screwed with the multiple limiting holes 3 and can pass through the side wall of the first slide 6 to press the first slider 19. When in use, the first slider 19 is clamped by rotating the limit bolt 4 into the corresponding limit hole 3 to press against the first slider 19 in the first slide groove 6, so that the positioning bracket 27 is locked at a preset height and does not slide. If the positioning bracket 27 needs to slide to adjust the height, the limit bolt 4 is rotated in the opposite direction to loosen the first slider 19.

[0034] According to needs, a locking mechanism can be provided for the side wall of each first slide groove 6, or a locking mechanism can be provided for the side wall of one, two or three of the four first slide grooves 6, both of which can realize the control of the sliding and positioning of the positioning bracket 27, and both belong to the scope of the concept of the present invention.

[0035] On the basis of the above implementation, it also includes a contact limit sensor 9 and a controller. The contact limit sensor 9 is arranged on the upper surface of the first support rod 10 of the positioning bracket 27 and is located directly below the second support rod 12. The contact limit sensor 9 and the stepper motor 16 are electrically connected to the controller. When the second support rod 12 approaches the first support rod 10, the second support rod 12 can contact the contact limit sensor 9. The contact limit sensor 9 senses the contact signal and transmits it to the controller. The controller controls the stepper motor 16 to pause according to the signal information and controls the moving distance of the pressing bracket 26, which is conducive to controlling the extrusion amount.

[0036] Based on the above implementation, the two second cross bars 11 are located on the long sides of the rectangular frame structure, and the two first cross bars 7 are located on the wide sides of the rectangular frame structure, which is beneficial to increase the number of batch collection positions.

[0037] Based on the above implementation, the plurality of pressure caps 13 and the plurality of spacing bars 8 are made of transparent materials, the lower edge of the pressure cap 13 is provided with a conspicuous edge line, and the upper edge of the spacing bar 8 is provided with a conspicuous edge line, which is more conducive to observation. The conspicuous edge line is, for example, a black, yellow or red line.

[0038] On the basis of the above implementation, it also includes two support members 33, which are respectively arranged on the outer sides of the two pillars 5 near the side of the hinge shaft 34, each of the support members 33 includes two third sliders 30, a triangular prism body 31 and two third sliding grooves 32, the two bottom surfaces of the triangular prism body 31 are right-angled triangle bottom surfaces, the triangular prism body 31 of this structure is also called a ditch, the edges of the triangular prism body 31 are in arc transition with the adjacent side surfaces, a rubber layer is arranged on the side of the triangular prism body 31, the two third sliding grooves 32 are arranged on the oblique side surface of the triangular prism body 31, and the two third sliding grooves 32 are parallel to the oblique side, the two third sliders 30 are respectively slidably matched and connected with the two third sliding grooves 32, so that the third slider 30 can slide along the third sliding groove 32, a rotating shaft is commonly passed through the two third sliders 30, the rotating shaft can rotate relative to the third slider 30, and the two ends of the rotating shaft are fixedly connected to the upper end of the outer side of the pillar 5. A connecting rod can also be arranged between the two supporting members 33 to facilitate synchronous operation. When in use, when the first bottom plate 1 and the second bottom plate overlap, are parallel to each other and placed horizontally, the third slider 30 slides to the upper end of the third slide groove 32 and is suspended on the upper end of the outer side of the support 5, see Figure 3As shown; when the first bottom plate 1 is flipped 90° relative to the second bottom plate 2, the third slider 30 is at the upper end of the third chute 32. At the same time, one side of the triangular prism body 31 abuts against the surface of the test bench 36. Then, pull the two triangular prism bodies 31 in a direction away from the support frame, so that the third slider 30 is located in the middle of the third chute 32. Continue to drive the electric telescopic rod 35 to extend, so that one side of the triangular prism body 31 abuts against and presses the surface of the test bench 36 again, and pause the electric telescopic rod 35 to provide a basis for collection.

[0039] Using the above animal serum sample separation and collection device of the present invention, the method for batch separating and collecting animal serum samples from batch centrifuged animal blood samples for separating serum is as follows: The technician first collects blood on-site, connects the connecting part 20 of the blood collection syringe 24 with the needle 38. After batch blood collection is completed, the syringe 24 after the needle 38 and the plunger 37 are disassembled is placed in the centrifuge for batch centrifugation operation. After centrifugation is completed, the second bottom plate 2 of the separation and collection device is fixed on the test bench 36, and the first bottom plate 1 is stacked above the second bottom plate 2 (at this time, the included angle between the first bottom plate 1 and the second bottom plate 2 is 0°). Start the stepping motor 16 to rotate forward to slide the pressing support 26 upward to a preset height, pause the stepping motor 16, and the pressing support 26 is stationary. At this time, it is the first set height for placing the syringe 24 into the support frame, and the first set height is greater than the height of the push rod 25 plus the height of the syringe 24. Then take out the batch centrifuged and stratified blood collection syringes 24. Without disassembling the sampling end cap at the upper end of the syringe 24, directly put the batch of syringes 24 into the separation through one opening on one side of the rectangular space in the shape of "匚", and pass the through hole at the bottom end of the syringe 24 through the push rod 25, and make the upper end surface of the push rod 25 press against the central groove at the bottom of the piston 23 in the syringe 24.

[0040] Then rotate the limit bolt 4 to loosen the first slider 19 of the positioning support 27, so that the positioning support 27 can slide along the axial direction of the pillar 5. Slide the upper edge of the positioning support 27 to be flush with the lower edge of the conical sampling end cap, or flush with the lower edge of the conical top of the syringe 24, or flush with the root of the connecting part 20 of the syringe 24. Then, through the limit bolt 4 at this position, press and clamp the first slider 19 of the positioning support 27 to lock and fix the positioning support 27 at this position.

[0041] Then the stepper motor 16 is started to reverse, and the pressing bracket 26 approaches the syringe 24 along the axial direction of the four pillars 5, and the connecting portion 20 at the top of the syringe 24 passes through the through hole 14 of the corresponding pressure cover 13, and the lower surface of the pressure cover 13 of the pressing bracket 26 contacts the sampling end cover of the syringe 24, and at the same time, the second support rod 12 approaches or contacts the first support rod 10, and the second support rod 12 contacts the contact limit sensor 9 of the first support rod 10, and the contact limit sensor 9 senses the contact signal and transmits it to the controller, and the controller controls the stepper motor 16 to pause according to the signal information, and the pressing bracket 26 stops, and at this time, the pressing bracket 26 reaches the second set height, so that the syringes 24 are supported in batches.

[0042] Then, the tube clamp 28 on each gland 13 through which the syringe 24 connection part 20 is penetrated clamps the EP tube 29 with the corresponding number, and each EP tube 29 corresponds to each syringe 24, and the opening of the EP tube 29 is tilted and covered above the through hole 14 in the vertical state and above the upper port of the syringe 24 connection part 20, see Figure 3 As shown; Then, the first bottom plate 1 is driven to flip relative to the second bottom plate 2 at a preset angle above the second bottom plate 2 by the driving member, and the batch of syringes 24 and the batch of EP tubes 29 on the tube clamp 28 are flipped synchronously, so that the syringes 24 on the first bottom plate 1 are horizontally or tilted downward, the serum closes the opening of the connecting part 20 of the syringe 24 or gathers toward the connecting part 20 of the syringe 24, and the EP tube 29 opens upward to maintain a stable state. Figure 5 , Figure 6 shown.

[0043] Then collect the amount of serum sample as needed (usually collect 1-2 ml into the EP tube), and slide the upper edge of the positioning bracket 27 to the scale line with a distance of 1-2 ml from the lower edge of the pressing bracket 26 by the limit bolt 4 of the above-mentioned operation locking mechanism, and fix it; Then the stepper motor 16 is started to reverse, and the pressing bracket 26 continues to move toward the syringe 24 along the axial direction of the four pillars 5, and pressure is applied to the syringe 24 along the axial direction of the push rod 25, so that the push rod 25 pushes the piston 23 to move a preset displacement toward the top of the syringe 24. At the same time, the second support rod 12 approaches or contacts the first support rod 10, and the second support rod 12 contacts the contact limit sensor 9 of the first support rod 10. The contact limit sensor 9 senses the contact signal and transmits it to the controller. The controller controls the stepper motor 16 to pause according to the signal information, and the pressing bracket 26 is stationary, so that the serum in the syringe 24 can be ejected from the through hole of the connecting part 20 of the syringe 24 to the EP tube 29 with a set amount of serum, so as to realize batch collection and effectively improve the efficiency of separating and collecting serum. It does not need to rely on the skilled skills of technicians in pouring control, tilting position and pouring amount, and the operation is fast and easy to operate.

[0044] The number of devices and processing scales described here are used to simplify the description of the present invention. Applications, modifications and variations of the present invention will be obvious to those skilled in the art.

[0045] Although the embodiments of the present invention have been disclosed as above, they are not limited to the applications listed in the specification and the implementation modes, and they can be fully applied to various fields suitable for the present invention. For those familiar with the art, additional modifications can be easily implemented. Therefore, without departing from the general concept defined by the claims and the scope of equivalents, the present invention is not limited to the specific details and the examples shown and described herein.

Claims

1. An animal serum sample separation and collection device, comprising a blood collector, wherein the top of the syringe of the blood collector is provided with a connecting portion that passes through the syringe, characterized in that: Also includes: A support frame, comprising a rectangular first bottom plate, a rectangular second bottom plate and four pillars, the four pillars are respectively and vertically fixed at four corners of the upper surface of the first bottom plate, so that the four pillars surround a rectangular frame structure on the first bottom plate, a plurality of push rods adapted to the through holes at the bottom end of the syringe of the blood collector are vertically arranged on the upper surface of the first bottom plate, the push rods are used to penetrate the through holes at the bottom end of the syringe and the upper end surfaces of the push rods are pressed against the central groove at the bottom of the piston in the syringe, one side of the first bottom plate is hinged to one side of the second bottom plate, and the first bottom plate can be flipped relative to the second bottom plate by 0°~135° around the hinge shaft above the second bottom plate; a driving member for driving the first bottom plate to flip is arranged on the opposite side where the first bottom plate and the second bottom plate are hinged; A downward pressing bracket, which is located above the first bottom plate and can be slidably connected along the axial direction of the four pillars; the downward pressing bracket includes two second cross bars, a plurality of pressure covers and a plurality of second support rods, the two second cross bars are respectively arranged on opposite sides of the rectangular frame structure, the plurality of second support rods are parallel to each other and span between the two second cross bars in the same plane, one or two pressure covers are arranged in the middle of each second support rod, a through hole is penetrated in the center of the pressure cover, the aperture of the through hole is greater than or equal to the root outer diameter of the top connecting part of the syringe, and smaller than the inner diameter of the syringe, and the through hole is used to supply pressure directly below the pressure cover The top connecting part of the syringe passes through; the second support rod or the upper surface of the gland is provided with a tube clamp for clamping the EP tube, the central axis of the tube clamp and the central axis of the through hole of the gland are in the same plane, and the plane is perpendicular to the hinge shaft, the angle between the extension line of the central axis of the tube clamp and the gland is 10°~45°, so that when the tube clamp clamps the EP tube, the opening of the EP tube is tilted and covered above the through hole in a vertical state, the tube clamp is arranged close to the hinge shaft side, each of the tube clamps and each of the push rods corresponds to each of the glands one by one, and the push rods coincide with the central axis of the through hole of the corresponding gland.

2. The animal serum sample separation and collection device according to claim 1, characterized in that: The pressing down bracket can be slidably connected along the axial direction of the four pillars as follows: two second cross bars are parallel to each other and are parallel to the first base plate in the same plane, and a square second slider is fixed at both ends of each second cross bar, and a second slide groove matching the second slider is arranged on the opposite sides of the two pillars on the corresponding sides of the rectangular frame structure; it also includes a driving mechanism for driving the pressing down bracket to slide axially along the four pillars, and the driving mechanism includes a ball screw and a stepper motor, and the ball screw is arranged in the second slide groove along the axial direction of the pillar, one end of the ball screw is rotatably connected to the upper wall of the second slide groove through a bearing, and the other end is connected to the output end of the stepper motor, the stepper motor base is fixedly connected to the first base plate, and the second slider is fixedly connected to the nut of the ball screw.

3. The animal serum sample separation and collection device according to claim 2, characterized in that: The through hole of the gland is a tapered through hole that is larger at the bottom and smaller at the top. The inner diameter of the upper opening of the tapered through hole is equal to or slightly larger than the outer diameter of the root of the top connecting part of the syringe, and the inner diameter of the lower opening of the tapered through hole is equal to or slightly larger than the inner diameter of the syringe.

4. The animal serum sample separation and collection device according to any one of claims 1 to 3, characterized in that: It also includes a positioning bracket, which is located between the pressing down bracket and the first bottom plate and can be slidably connected along the axial direction of the four pillars, and the positioning bracket, the pressing down bracket and the first bottom plate are parallel to each other; the positioning bracket includes two first cross bars, a plurality of spacer bars and a first support rod, the two first cross bars are respectively arranged on the other opposite sides of the rectangular frame structure, the first support rod spans between the two first cross bars, the plurality of spacer bars are respectively equidistant and vertically arranged on one side or both sides of the first support rod, the plurality of spacer bars are parallel to each other and are in the same plane as the first support rod and the first cross bar, the distance between two adjacent spacer bars is equal to or slightly larger than the outer diameter of the syringe, the rectangular space between two adjacent spacer bars corresponds one to one with each of the pressure caps, and the rectangular median line of the rectangular space intersects perpendicularly with the central axis of the corresponding pressure cap through hole, and the rectangular median line is parallel to the spacer bars.

5. The animal serum sample separation and collection device according to claim 4, characterized in that: The positioning bracket can be slidably connected along the axial direction of the four pillars as follows: two first cross bars are parallel to each other and the plane in the same plane is parallel to the first bottom plate, a square first sliding block is fixed at both ends of each first cross bar, and first sliding grooves matching the first sliding blocks are provided on the opposite side surfaces of the two pillars on the corresponding sides of the rectangular frame structure; a locking mechanism for clamping and releasing the first sliding block is provided on the pillars with the first sliding grooves; the locking mechanism includes a plurality of limiting holes and a plurality of limiting bolts, the plurality of limiting holes are arranged in sequence along the axial direction of the pillars of the first sliding groove, the plurality of limiting holes all penetrate the side walls of the first sliding groove, the plurality of limiting bolts are correspondingly screwed to the plurality of limiting holes, and can pass through the side walls of the first sliding groove to press the first sliding block.

6. The animal serum sample separation and collection device according to claim 5, characterized in that: It also includes a contact limit sensor and a controller. The contact limit sensor is arranged on the upper surface of the first support rod of the positioning bracket and is located directly below the second support rod. The contact limit sensor and the stepper motor are electrically connected to the controller.

7. The animal serum sample separation and collection device according to any one of claims 1 to 3 or 5 to 6, characterized in that: The two second cross bars are located on the long frames on both sides of the rectangular frame structure, and the two first cross bars are located on the wide frames on both sides of the rectangular frame structure.

8. The animal serum sample separation and collection device according to claim 7, characterized in that: The plurality of pressure covers and the plurality of spacer bars are all made of transparent material; a conspicuous edge line is arranged at the lower edge of the pressure covers, and a conspicuous edge line is arranged at the upper edge of the spacer bars.

9. The animal serum sample separation and collection device according to claim 8, characterized in that: It also includes two support members, which are respectively arranged on the outside of two pillars close to the hinge shaft side, each of the support members includes two third sliders, a triangular prism body and two third sliding grooves, the two bottom surfaces of the triangular prism body are right-angled triangle bottom surfaces, the edges of the triangular prism body are transitioned into arc surfaces on two adjacent side surfaces, a rubber layer is arranged on the side of the triangular prism body, the two third sliding grooves are arranged on the oblique side surface of the triangular prism body, and the two third sliding grooves are parallel to the oblique sides, the two third sliders are respectively slidably matched and connected with the two third sliding grooves, a rotating shaft is commonly passed through the two third sliders, the rotating shaft can rotate relative to the third slider, and the two ends of the rotating shaft are fixedly connected to the upper ends of the outer sides of the pillars.

10. A method for separating and collecting animal serum samples, characterized in that: The animal serum sample separation and collection device as described in any one of claims 1-3 or 5-6 or 8-9 is used to separate and collect animal serum samples from animal blood samples that are centrifuged to separate serum in batches.