Hydrogel stretching device and method for infrared spectrum detection
By designing a hydrogel stretching device for infrared spectral detection, using an electric rotary wheel structure and an electric rotary table, the problems of insufficient structure of traditional hydrogel materials and space limitations of infrared spectroscopy technology are solved, effective stretching and real-time stress monitoring of hydrogel samples are achieved, and molecular interaction information is obtained.
Patent Information
- Application Number
- CN202510274506.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-10
- Publication Date
- 2025-06-06
AI Technical Summary
Due to the simple structure, lack of strength and ductility, traditional hydrogel materials are very prone to fracture and their application range is limited; while infrared spectroscopy technology is sensitive to air humidity, and samples need to be placed in a dry and sealed sample chamber during spectral collection. Conventional stretching devices cannot adapt to the space limitations of the sample chamber.
A hydrogel stretching device for infrared spectral detection is designed, and an electric rotor structure is adopted to ensure that the space volume occupied by the device itself remains unchanged during the sample stretching process, and is adapted to the sample chamber space limitations of the steady-state and transient infrared spectroscopy system. The device includes a frame assembly, a connecting assembly, a tensile assembly and a two-dimensional infrared spectrometer, which enables longitudinal stretching and real-time stress monitoring of the hydrogel through an electric rotary table and a tensile sensor.
The effective stretching of hydrogel samples during infrared spectral detection is achieved, the sample chamber space is avoided, the stress condition of the sample can be monitored in real time, and the molecular interaction information of the hydrogel during the stretching process is obtained through synchronous spectral measurement.
Smart Images
Figure CN120102288A_ABST
Abstract
Description
Technical Field
[0001] The invention belongs to the field of spectrum detection technology assistance, relates to a detection device for biochemical samples, and specifically relates to a hydrogel stretching device for infrared spectrum detection. Background Art
[0002] Hydrogel materials are formed by cross-linking of hydrophilic polymer chains in water, and have important applications in tissue engineering, drug release, soft electronics and other fields. Traditional hydrogel materials are very easy to break due to their simple structure, lack of strength and ductility, and their application range is severely limited. Research and development of high-strength and good tensile hydrogels, and their application in biomaterials, wearable devices and other fields, has very good prospects. Understanding the formation and interaction mechanism of hydrogels at the molecular level has become the key to improving the strength and tensile properties of hydrogels. The complex processes involved include electrostatic interactions, hydrogen bonds, hydrophobic interactions, and host-guest interactions. Infrared spectroscopy technology is the mainstream means to study this type of process, including Fourier infrared spectroscopy, two-dimensional infrared spectroscopy, transient infrared spectroscopy and other technologies, which reflect the molecular interactions of materials during deformation through changes in the frequency shift, coupling and intensity of infrared characteristic peaks. Infrared spectroscopy is extremely sensitive to air humidity. During the spectrum acquisition process, the sample must be placed in a dry and sealed sample chamber to avoid spectral noise caused by air humidity fluctuations. However, the modified hydrogel material can be stretched to several to dozens of times its original length, and conventional stretching devices cannot adapt to the space limitations of the sample chamber. Summary of the invention
[0003] The purpose of the present invention is to provide a hydrogel stretching device for infrared spectroscopy detection, which adopts an electric rotary wheel structure to ensure that the volume of the space occupied by the device itself remains unchanged during the sample stretching process, and is adapted to the sample chamber space limitations of steady-state and transient infrared spectroscopy systems.
[0004] The technical solution adopted by the present invention is:
[0005] A hydrogel stretching device for infrared spectrum detection includes a frame component, a connection component, a stretching component and a two-dimensional infrared spectrometer; the frame component includes a support plate 2, a groove 5, and a double-layer aluminum plate 6; the connection component includes an end effector 7 and a tension sensor 8; the stretching component includes an electric rotating table 9, a fixing plate 10, and a three-dimensional optical moving table 11.
[0006] The fixing plate 10 is fixedly arranged on the side of the electric rotating table 9, and the electric rotating table 9 is fixed on the supporting plate 2 by screws; the tension sensor 8 is fixedly arranged in the empty groove below the front aluminum plate in the double-layer aluminum plate 6, and the end effector 7 is fixed above the tension sensor 8, and the rear aluminum plate in the double-layer aluminum plate 6 is fixed on the groove 5 by the bottom screws, and the front and rear aluminum plates are fixed in parallel, and the groove 5 is fixed on the three-dimensional optical moving table 11; the two ends of the hydrogel are fixed by the end effector 7 and the fixing plate 10 respectively.
[0007] Furthermore, in the frame assembly, support columns 1 are fixed to the lower ends of both sides of the support plate 2, and fork-type pressing plates 4 are provided at the lower ends of the support columns 1 through double-layer threaded bases 3.
[0008] Furthermore, the electric rotating table 9 includes two threaded holes, which are arranged at positions corresponding to the threaded holes of the support plate 2, and the electric rotating table 9 is installed on the support plate 2 by screws;
[0009] Furthermore, through holes are provided on the two top corners of the support plate 2, corresponding to the threaded holes on the two support columns 1 for fixed support;
[0010] Furthermore, a fixing plate 10 is arranged around the side of the electric rotating table 9, and two threaded holes are respectively arranged at both ends of the fixing plate 10. The fixing plate 10 is fixed to the side of the electric rotating table 9 with screws, and galvanized iron wire is wound around the thread of the screw. As the screw rotates, the iron wire is tightened to fix the fixing plate 10 on the electric rotating table 9.
[0011] Furthermore, the rear aluminum plate in the double-layer aluminum plate 6 is provided with threaded holes corresponding to the threaded holes on the groove 5, and the double-layer aluminum plate 6 can be fixed to the groove 5 by screws. The bottom plate under the groove 5 is provided with threaded holes and can be fixed to the three-dimensional optical moving platform 11 by screws.
[0012] Furthermore, a circular light-transmitting hole is provided in the middle of the double-layer aluminum plate 6 , and a square empty groove is provided at the bottom of the front aluminum plate in the double-layer aluminum plate 6 for fixing the tension sensor 8 .
[0013] Furthermore, the aluminum plate behind the double-layer aluminum plate 6 slides into the groove 5 through the slide grooves on both sides of the groove 5 to position the end surface.
[0014] Furthermore, the tension sensor 8 has a threaded hole on it, which can be connected to the end effector 7. The end effector 7 has a toothed structure on it for clamping and fixing the hydrogel. The tension sensor 8 has two threaded holes at the bottom, which can be connected and fixed to the two threaded holes at the bottom of the groove 5.
[0015] Furthermore, a threaded hole is provided at the bottom of the support column 1, which corresponds to the threaded hole on the double-layer threaded base 3, and can be fixed to the double-layer threaded base 3 by screws, and then the double-layer threaded base 3 is fixed by a fork-type pressure plate 4.
[0016] Furthermore, the fork-type pressing plate 4 is provided with a long strip through hole, and the fork-type pressing plate 4 can be fixed on the table by screws through the long strip through hole.
[0017] Furthermore, the entire double-layer aluminum plate 6 and the groove 5 are fixed on the three-dimensional optical moving stage 11 .
[0018] A hydrogel stretching method for infrared spectroscopy detection, the specific process is as follows:
[0019] Connect the terminal of the tension sensor 8 to the control instrument, turn on the power supply, connect the power supply to the control instrument, so that the control instrument is in a measuring state, and then connect the electric rotating platform 9 to the motor motion controller, and then connect the end effector 7 to the power supply, and then adjust the position of the end effector 7 and the fixed plate 10 on the electric rotating platform 9 so that they are on the same horizontal plane, place the hydrogel between the fixed plate 10 on the electric rotating platform 9 and the end effector 7 below and clamp it, use the motor motion controller to rotate the electric rotating platform 9 to perform longitudinal stretching measurement, and when stretched to a certain extent, record the stretching distance of the hydrogel and the corresponding value of the tension sensor 8 through the motor motion controller; after the hydrogel is stretched, use a two-dimensional infrared spectrometer to transmit the light in the two-dimensional infrared spectrometer through the hydrogel material and the light-transmitting hole, and then measure the two-dimensional infrared spectrum of the hydrogel, and then analyze the changes in the length and thickness, the vibration mode of the group and chemical bond and other properties of the hydrogel during the stretching process.
[0020] The beneficial effects of the present invention are:
[0021] 1. The present invention can stretch the sample to any length by fixing a section of the sample on the electric rotating table 9, and the stretching range is not limited by the space of the sample chamber.
[0022] 2. The present invention adopts a tension sensor 8, which can monitor the stress condition of the sample in real time during the sample stretching process.
[0023] 3. The present invention can realize synchronous spectral measurement of the set stretching range through macro program (commercial spectrometer) or Labview coding (conventional transient spectroscopy system). When the program is running, the rotation angle range and rotation step of the electric rotating table need to be set. The electric rotating table records the spectrum and tensile meter coefficient once every rotation angle, and finally converts the angle, rotating table diameter and sample starting length into the sample stretching multiple. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] Figure 1 It is a front schematic diagram of the three-dimensional structure of the present invention;
[0025] Figure 2 It is a side schematic diagram of the three-dimensional structure of the present invention;
[0026] Figure 3 It is a schematic diagram of the three-dimensional structure of the electric rotating platform stretching assembly of the present invention;
[0027] Figure 4 Schematic diagram of the three-dimensional structure of the double-layer aluminum plate, groove, and end effector connection assembly of the present invention, wherein (a) is a schematic diagram of the three-dimensional structure of the double-layer aluminum plate, (b) is a schematic diagram of the three-dimensional structure of the groove, and (c) is a schematic diagram of the three-dimensional structure of the end effector;
[0028] Figure 5 Schematic diagram of the tension sensor of the present invention, wherein (a) is a bottom view, (b) is a top view, (c) is a main view, and (d) is a side view.
[0029] Figure 6 It is a schematic diagram of the screw thread of the present invention being wound around the iron wire and rotating;
[0030] In the figure: 1 support column, 2 support plate, 3 double-layer threaded base, 4 fork-type pressure plate, 5 groove, 6 double-layer aluminum plate, 7 end effector, 8 tension sensor, 9 electric rotating table, 10 fixing plate, 11 three-dimensional optical moving table. DETAILED DESCRIPTION
[0031] The present invention is further described in detail below in conjunction with the accompanying drawings:
[0032] See also Figure 1As shown, the present invention is a longitudinal stretching device for a two-dimensional infrared transient sample pool, comprising a frame component, a connecting component, a stretching component and a two-dimensional infrared spectrometer; the frame component comprises a support column 1, a support plate 2, a double-layer threaded base 3, a fork-type pressure plate 4, a groove 5, and a double-layer aluminum plate 6, and the connecting component comprises an end effector 7 and a tension sensor 8; the stretching component comprises an electric rotating table 9, a fixing plate 10, and a three-dimensional optical moving table 11, wherein the fixing plate 10 is fixedly arranged on the electric rotating table 9, the tension sensor 8 is fixedly arranged in an empty groove below the front aluminum plate in the double-layer aluminum plate 6, the end effector 7 is fixed above the tension sensor 8, and the rear aluminum plate in the double-layer aluminum plate 6 is fixed to the groove 5 by a bottom screw, and the front and rear aluminum plates are fixed in parallel; the electric rotating table 9 is fixed by screws It is fixed on the support plate 2; two M4 threaded holes are provided on the electric rotating table 9, and the threaded holes are arranged at positions corresponding to the M4 threaded holes on the support plate. The electric rotating table 9 can be fixed on the support plate 2 by using screws. Four M3 threaded holes are provided on the fixing plate 10, and the fixing plate 10 is fixed to the cylindrical side of the electric rotating table 9 by screws. At the same time, galvanized iron wire is wrapped around the thread of the screw. As the screw rotates, the iron wire is tightened to fix the fixing plate 10 on the cylindrical side of the electric rotating table 9; M6 threaded holes and M3 threaded holes are provided on the groove 5, among which the two M6 threaded holes on the bottom plate below the groove 5 can fix the groove 5 on the three-dimensional optical moving table 11 by screws, and the M3 threaded holes on both sides of the groove 5 can correspond to the threaded holes on the rear aluminum plate in the double-layer aluminum plate 6. The aluminum plate behind the double-layer aluminum plate 6 can slide into the groove 5 through the slide grooves on both sides of the groove 5. At the same time, the aluminum plate behind the double-layer aluminum plate 6 is provided with an M3 threaded hole, and the double-layer aluminum plate 6 can be fixed to the groove 5 by screws. After the double-layer aluminum plate 6 and the groove 5 are fixed, they cannot slide relative to each other. A circular light-transmitting hole is provided in the middle of the double-layer aluminum plate 6. After the two ends of a single hydrogel are vertically clamped by the fixing plate 10 and the end effector 7, light can be transmitted through the hydrogel material and the light-transmitting hole. The double-layer aluminum plate 6 is welded together by two iron sheets, and a square hole is provided at the bottom of the front aluminum plate for fixing the tension sensor 8. The tension sensor 8 is provided with an M3 threaded hole which can be connected with the end effector 7. The end effector 7 has a toothed structure which can be used to clamp and fix the hydrogel. The tension sensor 8 has two M2 threaded holes at the bottom which can be connected and fixed with the two threaded holes at the bottom of the groove 5. Before stretching, one side of the single hydrogel should be clamped between the inner side of the fixing plate 10 and the side of the cylindrical turntable of the electric rotating table 9, and the other side of the hydrogel should be clamped on the end effector 7. Then, the two ends of the single hydrogel should be in the same vertical plane before the stretching measurement can be performed.
[0033] See also Figure 2As shown, the support plate 2 mainly includes two M6 through holes and two M4 through holes. The M6 through holes are arranged at two top corners of the support plate 2, and the middle M4 through hole is arranged at the middle position of the support plate 2. An M6 threaded hole is arranged at the top and bottom of the two support columns 1, respectively. The through holes at the top corners correspond to the M6 threaded holes on the two support columns 1, so as to be fixed and supported by screws. The threaded holes at the middle position correspond to the threaded holes on the electric rotating table 9 and are fixed by screws. The two double-layer threaded bases 3 are respectively provided with M6 threaded holes and fixed by screws corresponding to the two threaded holes at the bottom of the support column 1, and then the double-layer threaded bases 3 are fixed by a fork-type pressing plate 4. The fork-type pressing plate 4 is provided with a long strip-shaped through hole, and the fork-type pressing plate 4 can be fixed on the table through the long strip-shaped through hole by screws.
[0034] The working method of the present invention is as follows: first, the bottom of the two support columns 1 is connected to the double-layer screw hole base 3, and then the base and the support column 1 are fixed with a fork-type pressure plate 4, and then the support plate 2 is connected to the top of the two support columns 1, and an electric rotating platform 9 with a motor is connected to the middle position of the support plate 2, and a fixing plate 10 is placed on the rotating platform, and then the plate behind the double-layer aluminum plate 6 is connected to the groove 5 through a slide groove, and then the double-layer aluminum plate 6 is fixed on the groove 5 with screws, and a tension sensor 8 is placed at the bottom of the aluminum plate in front of the double-layer aluminum plate 6. The tension sensor 8 is fixed between the aluminum plate and the base of the groove 5 through the hole at the bottom of the aluminum plate and the threaded hole below the tension sensor 8, and then an end effector 7 with screws is connected to the top of the tension sensor 8 through the threaded hole for clamping the hydrogel, and then the tension sensor 8 terminal is connected to the control instrument, and the entire double-layer aluminum plate 6 and the groove 5 are fixed on the three-dimensional optical moving table 11, and then the 24V adjustable power supply is turned on, and the adjustable power is turned on. The source is connected to the control instrument to put the instrument in a measuring state, and then the electric rotating platform 9 is connected to the motor motion controller, and then the end effector 7 is connected to the power supply. Next, the position of the end effector 7 and the fixed plate 10 on the electric rotating platform 9 is adjusted to be on the same horizontal plane. The hydrogel is placed between the fixed plate 10 on the electric rotating platform 9 and the end effector 7 below and clamped. The electric rotating platform 9 is rotated by the motor motion controller to perform longitudinal stretching measurement. When stretched to a certain extent, the motor motion controller records the stretching distance of the hydrogel and the corresponding value of the tension sensor 8. The two ends of a single hydrogel are measured by using a two-dimensional infrared spectrometer. After being vertically clamped by the fixed plate 10 and the end effector 7 and stretched, the light in the two-dimensional infrared spectrometer can be transmitted through the hydrogel material and the light-transmitting hole to measure the two-dimensional infrared spectrum of the hydrogel, and then the changes in the length and thickness, the vibration mode of the group and chemical bond and other properties of the hydrogel during the stretching process can be analyzed.
Claims
1. A hydrogel stretching device for infrared spectroscopy detection, characterized in that: The invention comprises a frame component, a connection component, a stretching component and a two-dimensional infrared spectrometer; the frame component comprises a support plate (2), a groove (5) and a double-layer aluminum plate (6); the connection component comprises an end effector (7) and a tension sensor (8); the stretching component comprises an electric rotating table (9), a fixing plate (10) and a three-dimensional optical moving table (11); The fixing plate (10) is fixedly arranged on the side of the electric rotating platform (9), and the electric rotating platform (9) is fixed on the support plate (2) by screws; the tension sensor (8) is fixedly arranged in the empty groove below the front aluminum plate in the double-layer aluminum plate (6), the end effector (7) is fixed above the tension sensor (8), the rear aluminum plate in the double-layer aluminum plate (6) is fixed on the groove (5) by bottom screws, the front and rear aluminum plates are fixed in parallel, and the groove (5) is fixed on the three-dimensional optical moving platform (11); the two ends of the hydrogel are fixed by the end effector (7) and the fixing plate (10) respectively.
2. The hydrogel stretching device for infrared spectrum detection according to claim 1, characterized in that: In the frame assembly, support columns (1) are fixed to the lower ends of both sides of the support plate (2), and fork-type pressing plates (4) are arranged at the lower ends of the support columns (1) via double-layer threaded bases (3).
3. The hydrogel stretching device for infrared spectrum detection according to claim 1, characterized in that: The electric rotating platform (9) includes two threaded holes, which are arranged at positions corresponding to the threaded holes of the support plate (2), and the electric rotating platform (9) is installed on the support plate (2) by means of screws; through holes are arranged at two top corners of the support plate (2), corresponding to the threaded holes on the two support columns (1), so as to provide fixed support.
4. The hydrogel stretching device for infrared spectrum detection according to claim 1, characterized in that: A fixing plate (10) is arranged around the side of the electric rotating platform (9), and two threaded holes are arranged at the two ends of the fixing plate (10). The fixing plate (10) is fixed to the side of the electric rotating platform (9) by screws, and a galvanized iron wire is wound around the screw thread. As the screw rotates, the iron wire is tightened so that the fixing plate (10) is fixed to the electric rotating platform (9).
5. The hydrogel stretching device for infrared spectrum detection according to claim 1, characterized in that: The rear aluminum plate in the double-layer aluminum plate (6) is provided with a threaded hole corresponding to the threaded hole on the groove (5), and the double-layer aluminum plate (6) can be fixed to the groove (5) by screws. The bottom plate below the groove (5) is provided with a threaded hole, and can be fixed to the three-dimensional optical moving platform (11) by screws. A circular light-transmitting hole is provided in the middle of the double-layer aluminum plate (6), and a square empty groove is provided at the bottom of the front aluminum plate in the double-layer aluminum plate (6) for fixing the tension sensor (8).
6. The hydrogel stretching device for infrared spectrum detection according to claim 1, characterized in that: The aluminum plate behind the double-layer aluminum plate (6) slides into the groove (5) through the slide grooves on both sides of the groove (5) to position the end surface.
7. The hydrogel stretching device for infrared spectrum detection according to claim 1, characterized in that: The tension sensor (8) has a threaded hole on it and can be connected to the end effector (7); the end effector (7) has a toothed structure on it and can be used to clamp and fix the hydrogel; the tension sensor (8) has two threaded holes on its bottom and can be connected and fixed to the two threaded holes on the bottom of the groove (5) in a corresponding manner.
8. The hydrogel stretching device for infrared spectrum detection according to claim 1, characterized in that: The support column (1) has a threaded hole at the bottom thereof, which corresponds to the threaded hole on the double-layer threaded base (3). The support column (1) can be fixed to the double-layer threaded base (3) by screws, and then the double-layer threaded base (3) is fixed by a fork-type pressing plate (4); the fork-type pressing plate (4) has a long strip through hole, and the fork-type pressing plate (4) can be fixed to the table by screws through the long strip through hole.
9. The hydrogel stretching device for infrared spectrum detection according to claim 1, characterized in that: The entire double-layer aluminum plate (6) and the groove (5) are fixed on a three-dimensional optical moving platform (11).
10. A hydrogel stretching method for infrared spectroscopy detection is carried out using a hydrogel stretching device for infrared spectroscopy detection according to any one of claims 1 to 9, characterized in that: The specific process is as follows: connecting the tension sensor (8) terminal to the control instrument, turning on the power supply, connecting the power supply to the control instrument, so that the control instrument is in a measuring state, and then connecting the electric rotating table (9) to the motor motion controller, and then connecting the end effector (7) to the power supply, and then adjusting the end effector (7) and the fixed plate (10) on the electric rotating table (9) so that they are on the same horizontal plane, placing the hydrogel between the fixed plate (10) on the electric rotating table (9) and the end effector (7) below and clamping, using the motor motion controller to rotate the electric rotating table (9) to perform longitudinal stretching measurement, when stretched to a certain extent, recording the stretching distance of the hydrogel and the corresponding value of the tension sensor (8) through the motor motion controller; after the hydrogel is stretched, using a two-dimensional infrared spectrometer, the light in the two-dimensional infrared spectrometer is transmitted through the hydrogel material and the light-transmitting hole, and then measuring the two-dimensional infrared spectrum of the hydrogel, and then analyzing the changes in the length and thickness of the hydrogel, the vibration mode of the group and chemical bond and other properties during the stretching process.