Disinfection wet tissue with monitoring and indicating functions and preparation method thereof

Abstract

The invention discloses a disinfection wet tissue with monitoring and indicating functions and a preparation method of the disinfection wet tissue. The disinfection wet tissue comprises the following components: 60-80% of a disinfectant and 20-40% of a disinfectant carrier. Wherein the disinfectant is composed of the following components: 0.1-1.0% of quaternary ammonium salt; 20-60% of a synergist; 0.005% to 0.05% of an indicator; 0.1 to 1.0 percent of a nonionic surfactant; 0.05 to 0.5 percent of pH (Potential of Hydrogen) regulator; 0.05 to 0.5 percent of a complexing agent; and the balance of purified water. The disinfectant carrier is mainly composed of non-woven fabric. The invention further discloses a preparation method of the disinfection wet tissue with the monitoring and indicating functions. The prepared wet tissue has cleaning and disinfecting functions and has a monitoring and indicating function; the disinfection area and the disinfection time can be monitored. The device is suitable for daily cleaning and disinfection and use compliance monitoring of medical institutions.

Description

Technical Field

[0001] The present invention relates to the field of surface cleaning and disinfection, and discloses a disinfection wet wipe with a monitoring and indicating function and a preparation method thereof. Background Art

[0002] For traditional surface cleaning and disinfection, first, a carrier such as a cotton towel is used to soak an aqueous solution containing a surfactant or an organic solvent and the like to wipe the surface of an object until it is clean, and then a disinfectant such as a chlorine-containing disinfectant or a quaternary ammonium salt disinfectant is used for spraying disinfection or wiping disinfection. This cleaning and disinfection method is not only time-consuming but also has the risks of cross-contamination and infection.

[0003] In recent years, disposable wet wipe products with cleaning and disinfection functions have made great progress. They have the advantage of completing cleaning and disinfection in one step, greatly saving time costs. At the same time, the wet wipes are disposable and can be discarded after use, avoiding the risks of cross-contamination and infection. However, due to the limited liquid content of disposable wet wipes, the wipeable area is limited, and there is a risk that the wiping range and the cleaning and disinfection effect are unknown during use. Summary of the Invention

[0004] In view of the above deficiencies of the prior art, the present invention provides a visual evaluation scheme during the cleaning and disinfection process, including a disinfection wet wipe with a monitoring and indicating function and a preparation method thereof. It can be used for visual monitoring and evaluation of the range and effect of surface cleaning and disinfection, aiming to solve the problem that it is difficult to directly confirm the cleaning range and disinfection effect when using disposable wet wipes for cleaning and disinfection.

[0005] According to an embodiment of the present invention, it is desired to provide a disinfection wet wipe that can effectively clean, achieve a medium-level disinfection effect, and has a monitoring and indicating function, and provide a preparation method for the aforementioned wet wipe.

[0006] According to the embodiment, a disinfection wet wipe with a monitoring and indicating function provided by the present invention is composed of the following weight components:

[0007] Disinfectant solution: 60 - 80%;

[0008] Disinfectant solution carrier: 20 - 40%;

[0009] Further, for the aforementioned disinfection wet wipe with a monitoring and indicating function, the disinfectant solution is composed of the following components in weight percentage:

[0010] Quaternary ammonium salt: 0.1 - 1.0%;

[0011] Synergist: 20 - 60%;

[0012] Indicator: 0.005 - 0.05%;

[0013] Surfactant: 0.1 - 1.0%;

[0014] pH regulator 0.05–0.5%;

[0015] Complexing agent 0.05–0.5%;

[0016] The balance is purified water.

[0017] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the quaternary ammonium salt in the disinfectant solution is one or a combination of didecyldimethylammonium chloride, benzalkonium chloride, cetyltrimethylammonium bromide, benzalkonium bromide.

[0018] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the synergist in the disinfectant solution is one or a combination of ethanol, isopropanol, and n-propanol.

[0019] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the indicator in the disinfectant solution is one or a combination of methylene blue, indigo, phenolphthalein, bromothymol blue, and bromocresol purple.

[0020] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the non-ionic surfactant in the disinfectant solution is an alkynol surfactant.

[0021] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the pH regulator in the disinfectant solution is one or a combination of sodium (potassium) hydroxide, triethanolamine, sodium (potassium) carbonate, sodium (potassium) bicarbonate, disodium (potassium) hydrogen phosphate, and borax.

[0022] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the pH of the disinfectant solution is 8.0 - 10.0.

[0023] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the complexing agent in the disinfectant solution is one or a combination of sodium salt of ethylenediaminetetraacetic acid, citrate, sodium salt of iminodisuccinic acid, and sodium salt of glutamic acid diacetic acid.

[0024] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the manufacturing steps of the disinfectant solution are as follows: sequentially add purified water, quaternary ammonium salt, synergist, indicator, surfactant, and complexing agent into a container, stir and dissolve them, and then add the pH regulator to obtain the disinfectant solution.

[0025] Furthermore, for the above-mentioned disinfection wet wipes with monitoring and indicating functions, the carrier of the disinfectant solution is one of non-woven fabrics.

[0026] Furthermore, for the preparation method of the above-mentioned disinfection wet wipes with monitoring and indicating functions, it is characterized by including the following steps:

[0027] In the present invention, the purified water is prepared according to the requirements of the Chinese Pharmacopoeia.

[0028] According to an embodiment, a method for preparing a disinfected wet wipe with a monitoring and indicating function provided by the present invention includes the following steps: a disinfected wet wipe with a monitoring and indicating function is obtained by soaking a disinfectant carrier with a disinfectant.

[0029] Compared with the prior art, subsequent test examples will prove that the present invention has the following advantages:

[0030] In the present invention, quaternary ammonium salts can react with molecules such as methylene blue, indigo, phenolphthalein, bromothymol blue, bromocresol purple in a specific ratio to form a quaternary ammonium salt-indicator conjugate. This conjugate breaks the property that quaternary ammonium salts lose their bactericidal ability due to anion antagonism in the system of the present invention. It has the ability to not affect the bactericidal effect of quaternary ammonium salts, and at the same time can immediately develop color after spraying a specific color developer. After developing color, it immediately starts to degrade and fade after reacting with oxygen in the air, etc. This degradation and fading is related to the quaternary ammonium salt-indicator conjugate remaining on the surface of the object. Therefore, within a certain period of time, the quaternary ammonium salt can be monitored by spraying the specific color developer again. It is found through experiments that this property is particularly suitable for monitoring the continuous action time of quaternary ammonium salts and does not interfere with or affect the actual application of the product.

[0031] The present invention discovers that after adding 20%-60% synergist, such as isopropyl alcohol, on the one hand, it can greatly improve the disinfection effect of quaternary ammonium salts. After acting for 1 minute, the killing logarithm of Mycobacterium chelonae can be >4.00, achieving medium-level disinfection. On the other hand, when the synergist is used in combination with a surfactant, it can enhance the overall cleaning effect, inhibit the generation of foam and accelerate the dissipation rate of foam. At the same time, the synergist has rapid volatility, making the product have the characteristic of quick drying after cleaning. Generally, adding the synergist can enhance the disinfection ability, significantly improve the cleaning effect, and reduce the waiting time after cleaning and disinfection.

[0032] In the present invention, 0.10%-1.0% alkynol surfactants in non-ionic surfactants are added. On the one hand, while improving the cleaning effect, it has the advantages of low foam, foam inhibition, and defoaming. On the other hand, because alkynol surfactants also have a corrosion inhibition effect, they can replace conventional corrosion inhibitors to reduce the erosion of quaternary ammonium salts and the like on metals, expanding the use range of wet wipes. As described above, this corrosion inhibition effect has significant technological progress and economic benefits. Description of the Drawings

[0033] Figure 1 It is a control chart for the color development ability test of the present invention. Detailed Embodiments

[0034] The present invention will be further described below in conjunction with specific embodiments.

[0035] Example 1

[0036] In a reaction vessel, 49.5 kg of purified water, 0.3 kg of benzalkonium chloride, 50 kg of isopropanol, 0.01 kg of methylene blue, 0.02 kg of phenolphthalein, 0.5 kg of methylbutynol, and 0.05 kg of sodium ethylenediaminetetraacetate were added in sequence. After stirring evenly, the pH was adjusted to 9.0 with sodium hydroxide to prepare 100 kg of a disinfectant solution with a monitoring and indicating function. Then, the disinfectant solution was infiltrated into non-woven fabric to obtain a disinfected wet wipe with a monitoring and indicating function.

[0037] Example 2

[0038] In a reaction vessel, 65 kg of purified water, 0.6 kg of cetyltrimethylammonium bromide, 0.3 kg of benzalkonium bromide, 15 kg of isopropanol, 18 kg of ethanol, 0.01 kg of bromothymol blue, 0.02 kg of bromocresol purple, 1.0 kg of methylbutynol, and 0.10 kg of glutamate diacetate sodium salt were added in sequence. After stirring evenly, the pH was adjusted to 9.5 with sodium carbonate to prepare 100 kg of a disinfectant solution with a monitoring and indicating function. Then, the disinfectant solution was infiltrated into non-woven fabric to obtain a disinfected wet wipe with a monitoring and indicating function.

[0039] Test Example 1 Testing the bactericidal ability of a disinfected wet wipe with a monitoring and indicating function

[0040] The bactericidal test was carried out according to the relevant provisions of the "Disinfection Technical Specification" (2002 edition). The original solution of the extruded liquid of the disinfected wet wipe was taken for testing, and the test results are shown in Table 1:

[0041] Table 1. Testing the bactericidal ability of a disinfected wet wipe with a monitoring and indicating function

[0042]

[0043] Conclusion: The original solution of the extruded liquid of the disinfected wet wipe prepared in Examples 1-2 of the present invention achieved intermediate water disinfection in 1 minute.

[0044] Test Example 2 Color development test of a disinfected wet wipe with a monitoring and indicating function

[0045] See Figure 1 , the upper left is the partition description, and the upper right shows: Take a wet wipe and clean and wipe it on a grayish-white melamine tabletop. As shown in the lower left, spray the color development spray ( Surface disinfection monitoring color developer) on the tabletop, and conduct color development tests at 0 minutes, 1 hour, 4 hours, 8 hours, and 12 hours after wiping. The test results are shown in Table 2:

[0046] Table 2

[0047]

[0048] Tests show that the disinfection wipes with monitoring and indicating functions prepared in Examples 1-2 have a color-developing monitoring effect and can achieve the monitoring function. Figure 1 The lower right shows the results of the color-developing experiment conducted 8 hours after wiping was completed.

[0049] Test Example 3 Metal Corrosion Test of Disinfection Wipes with Monitoring and Indicating Functions

[0050] According to GB / T 38498—2020 or the "Disinfection Technical Specification" (2002 Edition), disinfectant was taken for the metal corrosion test. The test results show that the disinfection wipes with monitoring and indicating functions prepared in Examples 1-2 have basically no corrosion effect on stainless steel, carbon steel, copper, and aluminum.

[0051] The above tests prove that the disinfection wipes with monitoring and indicating functions of the present invention can achieve medium-level disinfection in 1 minute, the prepared wipes have a color-developing effect, and have low metal corrosion, and are suitable for rapid cleaning, disinfection, and monitoring of the use effect of object surfaces.

[0052] Those skilled in the art should know that the above embodiments should be understood as only for illustrating the present invention rather than limiting the protection scope of the present invention. After reading the content recorded in the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalent changes and modifications also fall within the scope defined by the claims of the present invention.

Claims

1. A disinfectant wet wipe with monitoring and indicating function and a preparation method thereof, characterized in that: It is composed of the following components by weight: Disinfectant 60-80%; Disinfectant carrier 20-40%.

2. The disinfecting wet wipes with monitoring and indicating function according to claim 1, characterized in that: The disinfectant solution is composed of the following components in percentage by weight: Quaternary ammonium salt 0.1–1.0%; Synergist 20-60%; Indicator 0.005-0.05%; Nonionic surfactant 0.1-1.0%; pH adjuster 0.05– 0.5%; Complexing agent 0.05–0.5%; The balance is purified water.

3. The disinfecting wet wipes with monitoring and indicating function according to claim 2, characterized in that: The quaternary ammonium salt is didecyldimethylammonium chloride, benzalkonium chloride, hexadecyltrimethylammonium bromide, benzalkonium bromide, or one or a combination thereof.

4. The disinfecting wet wipes with monitoring and indicating function according to claim 2, characterized in that: The synergist is ethanol, isopropanol, n-propanol or a combination of several of them.

5. The disinfecting wet wipes with monitoring and indicating function according to claim 2, characterized in that: The indicator is one or a combination of methylene blue, indigo, phenolphthalein, bromothymol blue and bromocresol purple.

6. The disinfecting wet wipes with monitoring and indicating function according to claim 2, characterized in that: The nonionic surfactant is an acetylenic alcohol surfactant.

7. The disinfecting wet wipes with monitoring and indicating function according to claim 2, characterized in that: The pH regulator is one or more combinations of sodium (potassium) hydroxide, triethanolamine, sodium (potassium) carbonate, sodium (potassium) bicarbonate, disodium (potassium) hydrogen phosphate, and borax.

8. The disinfecting wet wipes with monitoring and indicating function according to claim 2, characterized in that: Its pH = 8.0-10.

0.

9. The disinfecting wet wipes with monitoring and indicating function according to claim 2, characterized in that: The complexing agent is one or more combinations of ethylenediaminetetraacetic acid sodium salt, citrate, iminodisuccinic acid sodium salt, and glutamic acid diacetic acid sodium salt.

10. The disinfectant wet wipes with monitoring and indicating functions according to claim 2, wherein the disinfectant preparation steps are as follows: adding purified water, quaternary ammonium salt, synergist, indicator, surfactant, and chelating agent into a container in sequence, stirring and dissolving, and then adding a pH adjuster to prepare the disinfectant.

11. The disinfecting wet wipes with monitoring and indicating function according to claim 1, characterized in that: The disinfectant carrier is a kind of non-woven fabric.

12. A method for preparing a disinfecting wet wipe with a monitoring and indicating function, characterized in that: The method comprises the following steps: soaking a disinfectant carrier in the disinfectant to obtain a disinfectant wet wipe with a monitoring and indicating function.

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