Oral liquid capable of clearing heat and diminishing inflammation

By using 7:2:1 heat-clearing and anti-inflammatory oral liquid with a ratio of dandelion, isatis root and mint, the problem of limited effectiveness of existing traditional Chinese medicine treatment products in the treatment of upper respiratory tract infections, pharyngitis and tonsillitis is solved, and rapid and effective treatment effects are achieved, and new treatment methods are provided for wind-heat viral keratitis of the liver meridian.

CN120168544APending Publication Date: 2025-06-20SHANGHAI PURUI EYE HOSPITAL CO LTD
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Patent Information

Application Number
CN202510553712.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-29
Publication Date
2025-06-20

AI Technical Summary

Technical Problem

The existing traditional Chinese medicine treatment products have limited effectiveness in treating diseases such as upper respiratory tract infections, pharyngitis and tonsillitis, especially in terms of rapid improvement of pharyngeal symptoms.

Method used

The ratio of the three drugs, dandelion, isatis root and mint is 7:2:1. The oral liquid for clearing and anti-inflammatory treatment is prepared by decoction, filtration and centrifugation, which is used to treat colds, sore throat, throat, tonsillitis, and wind-heat viral or bacterial keratitis or conjunctivitis of the liver meridian.

Benefits of technology

This oral liquid has a variety of effects such as clearing heat and detoxifying, clearing the liver and improving eyesight, antiviral, antibacterial, regulating immunity, evacuating wind-heat, and promoting pharyngeal palpitations. It can quickly and effectively treat the above diseases, and has developed the treatment function of wind-heat viral keratitis in the liver meridian for the first time.

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Abstract

The invention relates to the technical field of traditional Chinese medicine treatment, and discloses a heat-clearing and inflammation-diminishing oral liquid, which is characterized by comprising the following three medicines: dandelion, isatis root and mint, the ratio of dandelion to isatis root to mint is 7: 2: 1, and the heat-clearing and inflammation-diminishing oral liquid is obtained by decocting dandelion, isatis root and mint according to the ratio. The traditional Chinese medicine composition is mainly used for cold, swollen sore throat, sphagitis, tonsillitis and liver channel wind-heat type viral or bacterial keratitis or conjunctivitis, and has the effects of clearing away heat and toxic materials, clearing liver and improving eyesight, resisting viruses and bacteria, regulating immunity, dispelling wind and heat, relieving sore throat and the like; the traditional Chinese medicine composition can be used for scientifically and reasonably reducing therapeutic formula medicines, reducing the cost and fully exerting the synergistic effect between a single dose and the medicines, so that the purpose of rapid and effective treatment is achieved, and the function of treating the liver channel wind-heat type viral keratitis is developed for the first time.
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Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine treatment, and particularly relates to a Qingre Xiaoyan Oral Liquid. Background Art

[0002] The existing products with the effects of clearing heat and detoxifying, clearing the liver and improving eyesight, antiviral, antibacterial, regulating immunity, dispersing wind-heat, and relieving sore throat include: (1) Dandelion traditional Chinese medicine pieces, which belong to single-agent tea drinks. (2) Compound Gongying Tablets, a traditional Chinese medicine preparation composed of dandelion and isatis root, used for upper respiratory tract infections. (3) Isatis Root Granules, a single-agent preparation of Isatis tinctoria, used for febrile diseases with heat syndrome, maculae, wind-heat colds, swollen and festering throats, epidemic encephalitis B, hepatitis, mumps. (4) Pudilan Xiaoyan Oral Liquid, composed of dandelion, Patrinia scabiosaefolia, isatis root, and Scutellaria baicalensis, used for boils, mumps, pharyngitis, and tonsillitis.

[0003] Among the above products, dandelion traditional Chinese medicine pieces and similar products belong to health-care single-agent tea drinks, with weak targeted clinical treatment effects, and their effects are only limited to daily prevention. Compound Gongying Tablets are formulated with dandelion and isatis root. Theoretically, from the perspective of the efficacy of traditional Chinese medicine, they can be used for upper respiratory tract infections. However, this dosage form of medicine must be completely absorbed through the gastrointestinal tract and then circulated throughout the body to exert its effects, with no retention effect in the oral cavity and pharynx, and has limited effects on local inflammations such as pharyngitis and tonsillitis caused by upper respiratory tract infections, and is not conducive to the rapid improvement of pharyngeal symptoms. Isatis Root Granules, as a single-agent product, although theoretically can play a therapeutic role in various diseases such as febrile diseases with heat syndrome, maculae, wind-heat colds, swollen and festering throats, epidemic encephalitis B, hepatitis, and mumps, in clinical practice, the drug potency is limited and it is difficult to exert the expected therapeutic effect. Pudilan Xiaoyan Oral Liquid, with a multi-drug formulation, is used for the treatment of boils, mumps, pharyngitis, and tonsillitis, has a narrow treatment range, and there are still deficiencies in the improvement of pharyngeal symptoms and signs. Summary of the Invention

[0004] The present invention provides a Qingre Xiaoyan Oral Liquid, which is mainly used for colds, sore throats, pharyngitis, tonsillitis, and viral or bacterial keratitis or conjunctivitis of the liver meridian wind-heat type, and has the effects of clearing heat and detoxifying, clearing the liver and improving eyesight, antiviral, antibacterial, regulating immunity, dispersing wind-heat, and relieving sore throat; it can scientifically and reasonably reduce the therapeutic prescription drugs, reduce costs, give full play to the synergistic effect between single agents and drugs, so as to achieve a rapid and effective treatment purpose, and for the first time develop the treatment function of viral keratitis of the liver meridian wind-heat type.

[0005] The present invention provides a Qingre Xiaoyan Oral Liquid, which includes three drugs, namely: dandelion, isatis root, and mint. The ratio of dandelion, isatis root, and mint is 7:2:1. The dandelion, isatis root, and mint in this ratio are processed through the processes of decocting, filtering, and centrifuging to obtain the Qingre Xiaoyan Oral Liquid.

[0006] The present invention also provides a preparation method of the heat-clearing and anti-inflammatory oral liquid. Based on the above-mentioned heat-clearing and anti-inflammatory oral liquid, it includes the following steps:

[0007] S1. Clean the three kinds of medicines, namely dandelion, isatis root, and mint, with a proportion ratio of 7:2:1 respectively, and soak them in cold water for the first set time period;

[0008] S2. Decoct the dandelion and isatis root according to the set decocting ratio of water. After boiling, continue to decoct with slow fire for the second set time period;

[0009] S3. Put the mint in and decoct together for the third set time period, and the decocting ends;

[0010] S4. Filter and centrifuge the medicinal liquid to remove impurities and dandelion fibrils, and after sterilization and disinfection, it is sub-packed into oral liquid medicine bottles.

[0011] Further, in the step S1, the first set time period is 30 minutes.

[0012] Further, in the step S2, the set decocting ratio of water is 100 ml of water for every 20 grams of medicine.

[0013] Further, in the step S2, the second set time period is 15 minutes.

[0014] Further, in the step S3, the third set time period is 5 minutes.

[0015] The beneficial effects of the present invention are as follows:

[0016] The present invention uses three kinds of medicines, namely: dandelion, isatis root, and mint. Among them,

[0017] (1) Dandelion is cold in nature and has the effects of clearing heat and detoxifying and stimulating the body's immune function. It can be used to improve symptoms such as sores in the mouth and on the tongue, red and swollen eyes, and heartburn in the stomach.

[0018] (2) Isatis root has various pharmacological effects such as antibacterial, antiviral, anti-endotoxin, antipyretic, and anti-inflammatory. It clears heat and detoxifies, cools blood and relieves sore throat. The total alkaloids and amino acids in isatis root have obvious anti-inflammatory effects. It is a commonly used traditional Chinese medicine in clinical practice. Its chemical components include alkaloids, lignans, flavonoids, and nucleoside compounds, etc. It is mainly used for epidemic febrile disease with maculae, fever and sore throat, pestilence, carbuncle, erysipelas, etc. Currently, it is commonly used in clinical practice for the treatment of influenza, upper respiratory tract infection, mumps, acute and chronic hepatitis, etc.

[0019] (3) Peppermint has various pharmacological effects such as diaphoresis, antipyretic, analgesic, sedative, anti-pathogen, antispasmodic, inhibiting gastrointestinal smooth muscle contraction, cholagogic, lithagogue, and promoting transdermal absorption. Peppermint disperses wind-heat, clears the head and eyes, soothes the throat, promotes eruption, and soothes the liver and regulates qi, which endows it with the therapeutic value for eye diseases. Clinically, it is often used to treat influenza, headache, red eyes, fever, sore throat, gum swelling and pain, etc.

[0020] The combined application of these three herbs exerts a synergistic effect from three aspects: antiviral, antibacterial, and immunomodulatory. Dandelion is bitter in taste, sweet, and cold in nature, and belongs to the liver and stomach meridians; peppermint is pungent and cool, and belongs to the liver and lung meridians; isatis root is cold and bitter, and belongs to the heart and lung meridians. However, since isatis root is the root of Isatis indigotica Fort. of the Brassicaceae family and Baphicacanthus cusia (Nees) Bremek. of the Acanthaceae family, it also enters the liver meridian. The combined use of these three herbs disperses wind-heat and clears the head and eyes. From this perspective, it also has a good therapeutic effect on viral keratitis or conjunctivitis of the wind-heat type in the liver meridian. This obviously provides a new means for the treatment of viral keratitis on the basis of a simple, effective, abundant, and inexpensive prescription. Detailed implementation mode

[0021] It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0022] The present invention relates to the antiviral, antibacterial, and heat-clearing and detoxifying effects on various diseases.

[0023] The present invention provides a heat-clearing and anti-inflammatory oral liquid, which includes three herbs, namely: dandelion, isatis root, and peppermint. In terms of proportion, dandelion is used in a large amount, that is, the proportion of dandelion, isatis root, and peppermint is 7:2:1. The dandelion, isatis root, and peppermint in this proportion are processed through processes such as decocting, filtering, and centrifuging to obtain the heat-clearing and anti-inflammatory oral liquid; the Chinese medicine product name is: Helam Heat-Clearing and Anti-Inflammatory Oral Liquid.

[0024] Helam Heat-Clearing and Anti-Inflammatory Oral Liquid, "Helam" is transliterated from the Latin prefixes of the three main herbs in the oral liquid: dandelion (Herba taraxaci), isatis root (Radix isatidis), and peppermint (Mentha canadensis). Helam Heat-Clearing and Anti-Inflammatory Oral Liquid has the effects of clearing heat and detoxifying, clearing the liver and improving eyesight, antiviral, antibacterial, regulating immunity, dispersing wind-heat, soothing the throat, etc., and is mainly used for colds, sore throats, pharyngitis, tonsillitis, and viral or bacterial keratitis or conjunctivitis of the wind-heat type in the liver meridian.

[0025] The present invention has the effects of clearing heat and detoxifying, clearing the liver and improving eyesight, antiviral, antibacterial, regulating immunity, dispersing wind-heat, relieving sore throat, etc. It is mainly used for colds, sore throats, pharyngitis, tonsillitis, and viral or bacterial keratitis or conjunctivitis of the liver meridian wind-heat type. It aims to scientifically and reasonably reduce the therapeutic formula drugs, reduce costs, and give full play to the synergistic effects between single agents and drugs, so as to achieve a rapid and effective treatment purpose, and for the first time develop the treatment function of viral keratitis of the liver meridian wind-heat type.

[0026] The present invention also provides a preparation method of the Qingre Xiaoyan Oral Liquid, which is a production process link of the Qingre Xiaoyan Oral Liquid, including the following steps:

[0027] S1. Clean the three drugs of dandelion, isatis root, and mint with a ratio of 7:2:1 respectively, and soak them in cold water for the first set time period (30 minutes, which can be adjusted according to specific needs and is not limited here);

[0028] S2. Decoct dandelion and isatis root according to the set decocting ratio of water (100 ml of water for every 20 grams of drugs, which can be adjusted according to specific needs and is not limited here), and continue to decoct with slow fire for the second set time period (15 minutes, which can be adjusted according to specific needs and is not limited here) after boiling;

[0029] S3. Put mint in and decoct together for the third set time period (5 minutes, which can be adjusted according to specific needs and is not limited here), and the decocting ends;

[0030] S4. Filter and centrifuge the medicinal liquid, filter out impurities and dandelion hairs, sterilize and disinfect, and then divide and pack it into 10 ml oral liquid medicine bottles.

[0031] Among the three drugs of the Qingre Xiaoyan Oral Liquid of the present invention:

[0032] (1) Dandelion is cold in nature and has the effect of clearing heat and detoxifying and stimulating the body's immune function. It can be used to improve symptoms such as sores in the mouth and tongue, red and swollen eyes, and heartburn in the stomach.

[0033] (2) Isatis root has various pharmacological effects such as antibacterial, antiviral, anti-endotoxin, antipyretic, and anti-inflammatory. It clears heat and detoxifies, cools the blood and relieves sore throat. The total alkaloids and amino acids in isatis root have obvious anti-inflammatory effects. It is a commonly used traditional Chinese medicine in clinical practice, and its chemical components include alkaloids, lignans, flavonoids, and nucleoside compounds, etc. It is mainly used for epidemic febrile disease with maculae, fever and sore throat, pestilence, carbuncle, erysipelas, etc. Currently, it is commonly used in clinical treatment of influenza, upper respiratory tract infection, epidemic parotitis, acute and chronic hepatitis, etc.

[0034] (3) Peppermint has a variety of pharmacological effects, such as diaphoresis, antipyretic, analgesic, sedative, anti-pathogen, antispasmodic, inhibiting gastrointestinal smooth muscle contraction, cholagogic, lithagogue, and promoting transdermal absorption. Peppermint disperses wind-heat, clears the head and eyes, relieves sore throat, promotes eruption, soothes the liver and regulates qi, which endows it with the therapeutic value for eye diseases. Clinically, it is often used to treat influenza, headache, red eyes, fever, sore throat, gum swelling and pain, etc.

[0035] Combining the three drugs and applying them together synergistically exerts its effects from three aspects: antiviral, antibacterial and immune.

[0036] Dandelion is bitter in taste, sweet and cold in nature, and belongs to the liver and stomach meridians; peppermint is pungent and cool, and belongs to the liver and lung meridians; isatis root is cold and bitter, and belongs to the heart and lung meridians. However, since isatis root is the root of Isatis indigotica Fort. of the Cruciferae family and Baphicacanthus cusia (Nees) Bremek. of the Acanthaceae family, it also enters the liver meridian. The three herbs used together disperse wind-heat and clear the head and eyes. From this perspective, it also has a good therapeutic effect on viral keratitis or conjunctivitis of the pattern of wind-heat in the liver meridian. Obviously, on the basis of a simple, effective, abundant and inexpensive prescription, it provides a new means for the treatment of viral keratitis.

[0037] It should be noted that in this article, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, device, article or method comprising a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, device, article or method. Without further limitation, an element defined by the statement "comprising a..." does not exclude the existence of additional identical elements in the process, device, article or method comprising that element.

[0038] The above are only the preferred embodiments of the present invention, and do not limit the patent scope of the present invention accordingly. Any equivalent structural or equivalent process transformation made by using the content of the specification of the present invention, or directly or indirectly applied in other related technical fields, shall be similarly included in the patent protection scope of the present invention.

Claims

1. An oral liquid for clearing away heat and reducing inflammation, characterized in that: The invention comprises three medicines, namely: dandelion, isatis root and mint, wherein the ratio of dandelion, isatis root and mint is 7:2:1, and the dandelion, isatis root and mint in the ratio are subjected to a decoction, filtration and centrifugation process to obtain the heat-clearing and anti-inflammatory oral liquid.

2. A method for preparing a heat-clearing and anti-inflammatory oral liquid, characterized in that: The heat-clearing and anti-inflammatory oral liquid according to claim 1 comprises the following steps: S1, washing three kinds of medicines, namely dandelion, isatis root and mint, in a ratio of 7:2:1, respectively, and soaking them in cold water for a first set period of time; S2, boiling dandelion and isatis root according to the set decoction ratio, and continuing to boil over low heat for a second set time period after boiling; S3, adding mint and decocting together for a third set time period, and the decocting is finished; S4. Filter the liquid medicine to remove impurities and dandelion cilia, centrifuge, sterilize and then pack the oral liquid into medicine bottles.

3. The method for preparing the heat-clearing and anti-inflammatory oral liquid according to claim 1, characterized in that: In step S1, the first set time period is 30 minutes.

4. The method for preparing the heat-clearing and anti-inflammatory oral liquid according to claim 1, characterized in that: In step S2, the decoction ratio is set to 100 ml of water for every 20 grams of medicine.

5. The method for preparing the heat-clearing and anti-inflammatory oral liquid according to claim 1, characterized in that: In step S2, the second set time period is 15 minutes.

6. The method for preparing the heat-clearing and anti-inflammatory oral liquid according to claim 1, characterized in that: In step S3, the third set time period is 5 minutes.