A 3D printing device for orthopedic materials based on stem cells

Abstract

The present application relates to a 3D printing device for orthopedic materials based on stem cells, which belongs to the field of 3D printing and includes a base, a support plate mounted on the base, a Y-axis slide mounted on the support plate, a fixed frame fixedly connected between two adjacent bases, a Z-axis slide mounted on the fixed frame, an X-axis slide mounted on the Z-axis slide, a nozzle fixedly provided on the X-axis slide, a feed port provided above the nozzle, a first connecting plate mounted on the Y-axis slide, a hot bed provided on the first connecting plate, a pressure rod provided on the base, a fixed block welded to the pressure rod, a pressure block welded to the fixed block, and a connecting plate fixedly provided on the rear side of the X-axis slide. The present application solves the problem that the hot bed of existing 3D printers is usually a fixed plate structure, and it is not possible to use a multi-stage adjustable hot bed to quickly remove the support or printed material, and it is not possible to keep the material tray always following the nozzle.

Description

Technical Field

[0001] The present invention relates to a 3D printing device for orthopedic materials based on stem cells, belonging to the field of 3D printing. Background Art

[0002] 3D printing is a manufacturing technology that creates three-dimensional objects by adding materials layer by layer. Unlike traditional subtractive manufacturing methods such as cutting and milling, 3D printing uses computer control to build the final object layer by layer based on a digital model file. The core advantage of 3D printing lies in its ability to create complex geometric shapes, and it is widely used in various fields such as industry, medicine, architecture, aerospace, and education. 3D printing can reproduce complex bone structures and achieve precise bone tissue repair, but existing 3D printing equipment still has some limitations.

[0003] The invention patent with publication number CN105345001B discloses a 3D printer with a built-in titanium alloy nail plate for orthopedics, including a print head, a fixed plate at the bottom of the cross bar, a first motor and a second motor on the fixed plate, the bottom of the fixed plate is hinged to the print head, a first fixed shaft and a second fixed shaft are provided on the print head, a first wire is wound around the output shaft of the first motor, a second wire is wound around the output shaft of the second motor, and the first motor and the second motor are electrically connected to the PLC; a fan is provided in the workbench, and a fixing device is provided on both sides of the fan, the fixing device includes a cylinder and a piston, an end cover is provided at one end of the cylinder, and a bottom cover is provided at the other end, the piston is connected to the fixing rod, and a first spring is provided between the bottom cover and the piston. The printer's print head angle is easy to adjust and the printed products can be quickly cooled and formed. However, the hot bed of existing 3D printers is usually a fixed plate structure, which is not convenient for subsequent removal of low-height supports. It is not possible to use a multi-section adjustable hot bed to quickly remove supports or printed materials. In addition, existing 3D printing equipment cannot keep the material tray always following the nozzle during use and ensure that changes in the nozzle height do not affect the position of the material tray.

[0004] Therefore, we made improvements to this and proposed a 3D printing device for orthopedic materials based on stem cells. Summary of the Invention

[0005] (1) The technical problem to be solved by the present invention is that the heated bed of existing 3D printers is usually a fixed plate structure, which is not convenient for the subsequent removal of low-height supports, and it is not possible to use a multi-stage adjustable heated bed to quickly remove supports or printed materials. In addition, existing 3D printing equipment is unable to keep the material tray always following the nozzle during use and ensure that changes in the nozzle height do not affect the position of the material tray.

[0006] (2) Technical solution

[0007] In order to achieve the above-mentioned purpose of the invention, the present invention provides a 3D printing device for orthopedic materials based on stem cells, comprising a base, a support plate installed on the base, a Y-axis slide installed on the support plate, a fixed frame fixedly connected between two adjacent bases, a Z-axis slide installed on the fixed frame, an X-axis slide installed on the Z-axis slide, a nozzle fixedly provided on the X-axis slide, a feed port provided above the nozzle, a first connecting plate installed on the Y-axis slide, a hot bed provided on the first connecting plate, a pressure rod provided on the base, and the pressure rod A fixed block is welded on it, a pressure block is welded on the fixed block, a connecting plate is fixedly provided on the rear side of the X-axis slide, a side plate is fixedly connected to the connecting plate, a connecting block is fixedly provided above the side plate, a second connecting plate is provided above the connecting block, a buffer assembly is installed between the second connecting plate and the connecting block, a connecting plate and an adjustment assembly are respectively installed on both sides of the second connecting plate, a rotating assembly is provided in the middle of the connecting plate, a bracket is installed on the rotating assembly, a material tray is rotatably connected to the bracket, and a docking assembly is provided between the bracket and the material tray.

[0008] The bases are symmetrically distributed on both sides of the support plate, and the pressure rods are slidably connected to the bases.

[0009] The hot bed includes a fixed plate fixedly connected to the first connecting plate, a connecting shaft is rotatably mounted on the fixed plate, a rotating plate is fixedly connected to the connecting shaft, an extension rod is fixedly provided on the rotating plate, and a convex plate is fixedly provided on the first connecting plate.

[0010] Wherein, a chamfered surface is provided on a side of the extension rod close to the pressing block, the length of the extension rod is greater than the width of the first connecting plate, and the extension rods are distributed at equal intervals on the rotating plate.

[0011] Among them, the pressure block is fixedly connected to a fixing rod, and the fixing rod is fixedly provided with a push plate. The rotating plate is suitable for rotating counterclockwise when the extension rod abuts the pressure block. The pressure rod, fixed block, pressure block, fixing rod and push plate are fixedly connected to form an integral structure.

[0012] The connecting plate and the connecting block are not connected to each other, the connecting block and the fixing frame are slidably connected, a guide rod is slidably installed in the connecting block, and the guide rod and the side plate are fixedly connected.

[0013] The buffer assembly includes a slider slidably mounted in the connecting block, the slider and the second connecting plate are fixedly connected, and both sides of the slider are connected to the connecting block via a first spring and a second spring respectively.

[0014] Among them, the adjustment component includes a sliding rod slidably installed in the second connecting plate, the sliding rod and the connecting plate are fixedly connected, a stop block is fixedly provided above the second connecting plate, a third connecting plate is fixedly provided on the sliding rod, and an electric push rod is installed between the third connecting plate and the second connecting plate.

[0015] Among them, the rotating assembly includes a turntable rotatably installed in the middle of the connecting disk, the turntable and the bracket are fixedly connected, a first protrusion is fixedly provided on the turntable, a second protrusion is fixedly provided on the connecting disk, and an elastic rope is fixedly connected between the first protrusion and the second protrusion.

[0016] The docking assembly includes a first groove provided in the bracket, a rubber damping block is fixedly arranged in the first groove, a rubber ring is fixedly connected to the bracket, and a second groove for docking with the rubber damping block is provided on the material tray.

[0017] (3) Beneficial effects

[0018] The present invention provides a 3D printing device for orthopedic materials based on stem cells, which has the following beneficial effects:

[0019] 1. The first connecting plate and the hot bed are provided to realize the function of quickly removing the support. By pushing the pressing block, the inclined surface of the pressing block abuts against the extension rod on the hot bed, and the extension rods distributed alternately with the convex plates will be lifted as a whole, thereby separating the extension rods on the hot bed from the convex plates, thereby making it possible to quickly remove the printing materials stuck to the extension plates and the convex plates and the supports with lower heights, thereby enhancing the convenience of using the device. The device uses a detachable hot bed to solve the problem that existing 3D printing equipment cannot use a multi-section adjustable hot bed to quickly remove supports or materials.

[0020] 2. The function of material tray following printing is realized by setting the connecting plate, side plate and connecting block. As the X-axis slide slides on the Z-axis slide, the connecting plate will drive the side plate to move synchronously, and the connecting block will slide on the fixed frame, thereby driving the connecting plate and the material tray to move through the second connecting plate, so that the device will move left and right following the print head during printing, and because the side plate and the connecting block are connected for sliding in the vertical direction, the material tray will remain stationary when the printing nozzle moves up and down, ensuring that the feeding consumables can remain stable during printing, enhancing the stability of the device during operation, and solving the problem that the existing 3D printing equipment cannot keep the material tray always following the nozzle during use and ensure that the change in nozzle height does not affect the position of the material tray.

[0021] 3. The buffer component is set to ensure that the material tray has a certain buffer function in the process of following the nozzle, ensuring that when printing materials with complex shapes in the future, the material tray will not shake too much when following the printing, thereby enhancing the stability of the device during printing. The device is provided with an adjustment component and a rotation component. The elastic rope on the rotating component cooperates with the turntable to enable the angle of the material tray to automatically reset after deviation. The adjustment component can adjust the initial position of the material tray according to the number of rolls of consumables on the material tray, thereby ensuring that the consumables always remain vertical during discharge.

[0022] 4. Through the docking assembly, the material tray can be quickly docked with the bracket. By squeezing the rubber damping block, the material tray can be installed into the inside of the bracket, and the rubber damping block is docked with the second groove, so that the material tray can be stably docked with the bracket. The rubber ring creates a certain resistance when the material tray rotates, thereby ensuring that the consumables remain taut when the device is in use. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0024] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0025] Figure 2 for Figure 1 A magnified schematic diagram of the structure at center A;

[0026] Figure 3 for Figure 1 A magnified schematic diagram of the structure at B in the middle;

[0027] Figure 4 This is a schematic diagram of the connection structure between the base and the support plate of the present invention;

[0028] Figure 5 This is a schematic diagram of the connection structure between the connecting plate and the side plate of the present invention;

[0029] Figure 6 for Figure 5 A magnified schematic diagram of the structure at position C in the middle;

[0030] Figure 7 This is a schematic diagram of the split structure of the connecting block and the second connecting plate of the present invention;

[0031] Figure 8 for Figure 7 A magnified schematic diagram of the structure at D in the middle;

[0032] Figure 9This is a schematic diagram of the structure of the bracket and the tray of the present invention;

[0033] Figure 10 for Figure 9 A magnified schematic diagram of the structure at E in the middle;

[0034] Figure 11 This is a schematic diagram of the connection structure between the bracket and the docking assembly of the present invention;

[0035] Figure 12 This is a schematic diagram of the cross-sectional structure of the material tray of the present invention;

[0036] Figure 13 This is a schematic diagram of the connection structure between the first connecting plate and the hot bed of the present invention.

[0037] Figure numerals: 1, base; 2, support plate; 3, Y-axis slide; 4, fixed frame; 5, Z-axis slide; 6, X-axis slide; 7, nozzle; 8, first connecting plate; 9, hot bed; 901, fixed plate; 902, connecting shaft; 903, rotating plate; 904, extension rod; 905, chamfered surface; 906, convex plate; 10, pressure rod; 11, fixed block; 12, pressure block; 13, fixed rod; 14, push plate; 15, connecting plate; 16, side plate; 17, connecting block; 18, buffer assembly; 1801, slider; 1802, first spring; 1803, Second spring; 19. Guide rod; 20. Second connecting plate; 21. Connecting disk; 22. Adjusting assembly; 2201. Sliding rod; 2202. Stop block; 2203. Third connecting plate; 2204. Electric push rod; 23. Rotating assembly; 2301. Turntable; 2302. First protrusion; 2303. Second protrusion; 2304. Elastic rope; 24. Bracket; 25. Feed tray; 26. Feed port; 27. Docking assembly; 2701. First groove; 2702. Rubber damping block; 2703. Rubber ring; 2704. Second groove; 28. Magnetic plate. DETAILED DESCRIPTION

[0038] The following embodiments of the present invention are described in further detail in conjunction with the accompanying drawings and examples. The following embodiments are only used to illustrate the present invention and are not intended to limit the scope of the present invention.

[0039] Example 1:

[0040] like Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 、 Figure 6 、 Figure 7 、 Figure 8 、 Figure 9 、 Figure 10 、 Figure 11 、 Figure 12 and Figure 13As shown, this embodiment proposes a 3D printing device for orthopedic materials based on stem cells, including a base 1, a support plate 2 is installed on the base 1, a Y-axis slide 3 is installed on the support plate 2, a fixing frame 4 is fixedly connected between two adjacent bases 1, a Z-axis slide 5 is installed on the fixing frame 4, an X-axis slide 6 is installed on the Z-axis slide 5, a nozzle 7 is fixedly provided on the X-axis slide 6, the X-axis slide 6 is used to adjust the left and right positions of the nozzle 7, a feed port 26 is provided above the nozzle 7, the Z-axis slide 5 is used to adjust the up and down positions of the nozzle 7, a first connecting plate 8 is installed on the Y-axis slide 3, a hot bed 9 is provided on the first connecting plate 8, the Y-axis slide 3 is used to adjust the front and rear positions of the first connecting plate 8 and the hot bed 9, and the hot bed 9 can be unfolded in sections so that the bonded materials or supports can be quickly removed later. A pressure rod 10 is provided on the base 1, a fixed block 11 is welded on the pressure rod 10, a pressure block 12 is welded on the fixed block 11, the pressure block 12 can abut the hot bed 9, so that the hot bed 9 can be easily unfolded, a connecting plate 15 is fixedly provided on the rear side of the X-axis slide 6, a side plate 16 is fixedly connected to the connecting plate 15, a connecting block 17 is fixedly provided above the side plate 16, a second connecting plate 20 is provided above the connecting block 17, a buffer assembly 18 is installed between the second connecting plate 20 and the connecting block 17, the second A connecting disc 21 and an adjustment assembly 22 are respectively installed on both sides of the connecting plate 20. A rotating assembly 23 is provided in the middle of the connecting disc 21. A bracket 24 is installed on the rotating assembly 23. A material tray 25 is rotatably connected to the bracket 24. The adjusting assembly 22 is used to adjust the front and rear position of the material tray 25 to ensure that the consumables on the subsequent material tray 25 remain vertical during feeding. A docking assembly 27 is provided between the bracket 24 and the material tray 25. The docking assembly 27 allows the material tray 25 to be quickly docked or separated with the bracket 24. When the X-axis slide 6 slides left and right, the side plate 16 on the connecting plate 15 can abut the connecting block 17. The buffer assembly 18 on the connecting block 17 allows the second connecting plate 20 to slide left and right following the nozzle 7. When the nozzle 7 moves up and down, the side plate 16 can slide on the connecting block 17 and keep the height of the connecting block 17 unchanged, so that the material tray 25 on the device can follow the nozzle 7 to move left and right for printing, and the buffer assembly 18 can play a buffering function when following, ensuring the overall stability of the device.

[0041] Example 2:

[0042] The solution in Example 1 is further introduced below in conjunction with a specific working method, as described below:

[0043] like Figure 1 As a preferred embodiment, on the basis of the above method, the base 1 is further symmetrically distributed on both sides of the support plate 2, and the pressure rod 10 is slidably connected to the base 1. The sliding connection of the pressure rod 10 on the two bases 1 facilitates the subsequent rapid removal of the support with a lower height, thereby enhancing the convenience of the device when used.

[0044] like Figure 1 and Figure 13 As shown, as a preferred embodiment, on the basis of the above method, the hot bed 9 further includes a fixed plate 901 fixedly connected to the first connecting plate 8, a connecting shaft 902 is rotatably mounted on the fixed plate 901, a rotating plate 903 is fixedly connected to the connecting shaft 902, an extension rod 904 is fixedly provided on the rotating plate 903, and a convex plate 906 is fixedly provided on the first connecting plate 8. Figure 13 As can be seen in the figure, when the extension rod 904 is pushed upward, the extension rod 904 will rotate on the fixed plate 901 through the rotating plate 903, thereby removing the bonded material or support and the protruding plate 906, so as to facilitate the subsequent removal of the support or the printed orthopedic material.

[0045] like Figure 1 and Figure 13 As shown, as a preferred embodiment, on the basis of the above method, further, an inclined surface 905 is provided on the side of the extension rod 904 close to the pressing block 12, the length of the extension rod 904 is greater than the width of the first connecting plate 8, and the extension rods 904 are evenly spaced on the rotating plate 903. The evenly spaced extension rods 904 ensure the supporting effect of the device on the orthopedic material. After the inclined surface 905 of the extension rod 904 abuts against the pressing block 12, the extension rod 904 will be lifted. When removing the support or orthopedic material, there is no need to use tools such as a spatula to achieve the function of quick removal, thereby enhancing the convenience of using the device.

[0046] like Figure 1 and Figure 13 As shown, as a preferred embodiment, on the basis of the above method, further, a fixing rod 13 is fixedly connected to the pressure block 12, and a push plate 14 is fixedly provided on the fixing rod 13. The rotating plate 903 is suitable for rotating counterclockwise when the extension rod 904 abuts against the pressure block 12. The pressure rod 10, the fixed block 11, the pressure block 12, the fixed rod 13 and the push plate 14 are fixedly connected to form an integral structure. When the extension rod 904 is pushed by the pressure block 12, the extension rod 904 will be pushed upward, thereby causing the rotating plate 903 to rotate counterclockwise, so that the printed material can be quickly removed.

[0047] like Figure 13 As shown, as a preferred embodiment, on the basis of the above method, further, the bottom of the extension rod 904 is fixedly connected with a magnetic plate 28, and the first connecting plate 8 is made of magnetic metal. The magnetic plate 28 can stably adsorb the first connecting plate 8, so that the device can keep the extension rod 904 in a stable state during the printing process, ensuring the printing quality of the device while not affecting the subsequent deployment of the extension rod 904 from the first connecting plate 8.

[0048] like Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 、 Figure 6 and Figure 7 As shown, as a preferred embodiment, on the basis of the above-mentioned manner, further, the connecting plate 15 and the connecting block 17 are not connected to each other, the connecting block 17 and the fixing frame 4 are slidably connected, a guide rod 19 is slidably installed in the connecting block 17, and the guide rod 19 and the side plate 16 are fixedly connected. Figure 7 As can be seen in the figure, when the connecting plate 15 moves downward, the side plate 16 will slide on the connecting block 17, and the guide rod 19 ensures that the side plate 16 can move stably on the connecting block 17 and will not fall off.

[0049] like Figure 8 As shown, as a preferred embodiment, on the basis of the above method, the buffer assembly 18 further includes a slider 1801 slidably installed in the connecting block 17, the slider 1801 and the second connecting plate 20 are fixedly connected, and the two sides of the slider 1801 are respectively connected to the connecting block 17 through a first spring 1802 and a second spring 1803. The first spring 1802 and the second spring 1803 enable the slider 1801 to have a buffering effect while following the movement when the connecting block 17 moves left and right.

[0050] like Figure 1 、 Figure 3 、 Figure 5 、 Figure 6 and Figure 7 As shown, as a preferred embodiment, on the basis of the above method, further, the adjustment component 22 includes a slide rod 2201 slidably installed in the second connecting plate 20, the slide rod 2201 and the connecting disk 21 are fixedly connected, a stop block 2202 is fixedly provided above the second connecting plate 20, a third connecting plate 2203 is fixedly provided on the slide rod 2201, and an electric push rod 2204 is installed between the third connecting plate 2203 and the second connecting plate 20. The slide rod 2201 can drive the connecting disk 21 to slide on the second connecting plate 20 when the electric push rod 2204 on the third connecting plate 2203 is shortened, so that the device can change the initial position of the consumables according to the number of rolls of consumables used, to ensure that the consumables always maintain vertical feeding.

[0051] like Figure 6As shown, as a preferred embodiment, on the basis of the above method, further, the rotating component 23 includes a turntable 2301 rotatably installed in the middle of the connecting disk 21, the turntable 2301 and the bracket 24 are fixedly connected, a first protrusion 2302 is fixedly provided on the turntable 2301, a second protrusion 2303 is fixedly provided on the connecting disk 21, and an elastic rope 2304 is fixedly connected between the first protrusion 2302 and the second protrusion 2303. When the turntable 2301 on the device moves with the printing position, as the number of turns of the consumables used and the position of the consumables change, the turntable 2301 can rotate on the connecting disk 21, and the elastic rope 2304 resets the turntable 2301 by pulling the first protrusion 2302 and the second protrusion 2303.

[0052] like Figure 9 、 Figure 10 、 Figure 11 and Figure 12 As shown, as a preferred embodiment, on the basis of the above method, further, the docking component 27 includes a first groove 2701 opened in the bracket 24, a rubber damping block 2702 is fixedly arranged in the first groove 2701, a rubber ring 2703 is fixedly connected to the bracket 24, and a second groove 2704 for docking with the rubber damping block 2702 is opened on the material tray 25. The material tray 25 can squeeze the rubber damping block 2702, and the material tray 25 is installed on the bracket 24 so that the rubber damping block 2702 in the first groove 2701 is docked with the second groove 2704 on the material tray 25, so that the material tray 25 can be quickly disassembled and assembled. The rubber ring 2703 creates a certain resistance for the material tray 25 when it rotates, thereby ensuring that the consumables can remain in a straightened state when feeding, which not only ensures printing accuracy but also reduces the probability of blockage.

[0053] Example 3:

[0054] The solutions in Example 1 and Example 2 are further introduced below in conjunction with specific working methods, as described below:

[0055] Specifically, when using the stem cell-based orthopedic material 3D printing device: Figure 1 、 Figure 2 、 Figure 3 and Figure 4 As shown, the base 1 and the support plate 2 are used to support the entire device, the X-axis slide 6 is used to adjust the left and right position of the nozzle 7, the Z-axis slide 5 is used to adjust the up and down position of the nozzle 7, and the Y-axis slide 3 is used to adjust the front and back position of the first connecting plate 8 and the hot bed 9. The extension rod 904 and the protruding plate 906 on the hot bed 9 can be expanded in sections to quickly remove the bonded materials or supports. Figure 9 、 Figure 10 、 Figure 11 and Figure 12As shown, when the device is in use, the material tray 25 is installed on the bracket 24. When installed, the material tray 25 can squeeze the rubber damping block 2702. The rubber damping block 2702 in the first groove 2701 is docked with the second groove 2704 on the material tray 25. The rubber ring 2703 creates a certain resistance when the material tray 25 rotates, thereby ensuring that the consumables can remain in a straight state during feeding. Vertical feeding can ensure printing accuracy while reducing the probability of clogging of the nozzle 7. The first spring 1802 and the second spring 1803 ensure that when the connecting block 17 moves left and right, the slider 1801 and the second connecting plate 20 have a buffering effect while following the movement. When the X-axis slide 6 slides left and right on the Z-axis slide 5, the side plate 16 on the connecting plate 15 can abut the connecting block 17, and the buffer assembly 18 on the connecting block 17 allows the second connecting plate 20 to slide left and right with the nozzle 7. When the nozzle 7 moves vertically on the fixed frame 4 through the Z-axis slide 5, the side plate 16 can slide on the connecting block 17 and keep the height of the connecting block 17 unchanged, so that the material tray 25 on the device can move left and right with the nozzle 7 for printing, and when the nozzle 7 moves up and down, the material tray 25 is not affected.

[0056] Figure 13 As can be seen in the figure, since the pressure rod 10, the fixed block 11, the pressure block 12, the fixed rod 13 and the push plate 14 are a whole, when the push plate 14 is pushed, the inclined surface of the pressure block 12 can be used to abut the bevel 905 on the extension rod 904, so that the extension rod 904 is lifted, and the rotating plate 903 rotates counterclockwise on the fixed plate 901 through the connecting shaft 902, so that the material or support adhered to the protruding plate 906 is removed. When the device is removing the support or orthopedic material, there is no need to use tools such as a scraper. When the device is using the printing function, the consumables can be kept fed vertically, such as Figure 5 、 Figure 6 and Figure 7 As shown, the electric push rod 2204 between the third connecting plate 2203 and the second connecting plate 20 can change the initial position of the material tray 25. The slide bar 2201 can drive the connecting plate 21 to slide on the second connecting plate 20 when the electric push rod 2204 on the third connecting plate 2203 is shortened. This allows the device to change the initial position of the consumables according to the number of consumables used, ensuring that the consumables are always fed vertically. As the turntable 2301 on the device moves with the printing position, it can rotate on the connecting plate 21 as the number of consumables used and the position of the consumables change, ensuring stable feeding. The elastic cord 2304 pulls the first protrusion 2302 and the second protrusion 2303 to subsequently reset the turntable 2301.

[0057] It should be noted that stem cells are extracted from the patient or a healthy donor, cultured and expanded in vitro. The cultured stem cells are mixed with a biocompatible hydrogel material to create a 3D-printed orthopedic implant. Based on the three-dimensional data of the patient's bone defect, an implant matching the shape of the defect is printed. The printed implant is then cultured in vitro under specific culture conditions to promote the differentiation of stem cells into osteoblasts. Mature bone tissue implants are implanted into the patient's body to repair and regenerate bone tissue. This device utilizes the patient's own stem cells to reduce immune rejection reactions. The mechanical properties of the implant can be optimized by adjusting the material and structure. Implants are customized according to the patient's actual condition to improve the treatment effect. The use of stem cells helps accelerate the repair and regeneration of bone tissue.

[0058] The above embodiments are intended to illustrate the present invention only and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the embodiments, it should be understood by those skilled in the art that various combinations, modifications, or equivalent substitutions of the technical solutions of the present invention do not depart from the spirit and scope of the technical solutions of the present invention and should be encompassed by the scope of the claims of the present invention.

Claims

1. A 3D printing device for orthopedic materials based on stem cells, comprising a base, characterized in that: The support plate is fixedly provided with the Y-axis slide, and a fixing frame is fixed between two adjacent bases, and the fixing frame is installed. The Z-axis slide is installed, and the X-axis slide is fixedly provided with a nozzle, and a feed inlet is provided above the nozzle. The first connecting plate is installed on the first connecting plate, and a hot bed is provided on the base. The base is provided with a pressure rod, and a fixing block is welded on the pressure rod, and a pressure block is welded on the fixed block. A connecting plate is fixedly provided on the rear side of the X-axis slide, and a side plate is fixedly connected to the connecting plate, and a connecting block is fixedly provided above the side plate, and a second connecting plate is provided above the connecting block. A buffer assembly is installed between the second connecting plate and the connecting block, and a connecting disk and an adjusting assembly are respectively installed on both sides of the second connecting plate. A rotating assembly is provided in the middle of the connecting disk. A bracket is installed on the rotating assembly, and a material tray is rotatably connected to the bracket, and a docking assembly is provided between the bracket and the material tray. The hot bed includes a fixed plate fixedly connected to the first connecting plate, a connecting shaft is rotatably mounted on the fixed plate, a rotating plate is fixedly connected to the connecting shaft, an extension rod is fixedly provided on the rotating plate, and a convex plate is fixedly provided on the first connecting plate.

2. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The bases are symmetrically distributed on both sides of the support plate, and the pressure rods are slidably connected to the bases.

3. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: A chamfered surface is provided on one side of the extension rod close to the pressing block. The length of the extension rod is greater than the width of the first connecting plate. The extension rods are distributed on the rotating plate at equal intervals.

4. The stem cell-based orthopedic material 3D printing device according to claim 3, characterized in that: The pressing block is fixedly connected with a fixing rod, and the fixing rod is fixedly provided with a push plate. The rotating plate is suitable for rotating counterclockwise when the extension rod abuts against the pressing block. The pressing rod, fixing block, pressing block, fixing rod and push plate are fixedly connected to form an integral structure.

5. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The connecting plate and the connecting block are not connected to each other, the connecting block and the fixing frame are slidably connected, a guide rod is slidably installed in the connecting block, and the guide rod and the side plate are fixedly connected.

6. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The buffer assembly includes a slider slidably mounted in the connecting block, the slider is fixedly connected to the second connecting plate, and both sides of the slider are connected to the connecting block via a first spring and a second spring respectively.

7. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The adjustment assembly includes a sliding rod slidably installed in the second connecting plate, the sliding rod and the connecting plate are fixedly connected, a stop block is fixedly provided above the second connecting plate, a third connecting plate is fixedly provided on the sliding rod, and an electric push rod is installed between the third connecting plate and the second connecting plate.

8. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The rotating assembly includes a turntable rotatably installed in the middle of the connecting disk, the turntable and the bracket are fixedly connected, a first protrusion is fixedly provided on the turntable, a second protrusion is fixedly provided on the connecting disk, and an elastic rope is fixedly connected between the first protrusion and the second protrusion.

9. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The docking assembly includes a first groove opened in the bracket, a rubber damping block is fixedly arranged in the first groove, a rubber ring is fixedly connected to the bracket, and a second groove for docking with the rubber damping block is opened on the material tray.

Images