Preservation device for multiple pathogen detection, control system and control method
By designing a storage device for multiple pathogen detection, using the control unit to determine the storage plan and control each component of the storage device, the problem that the existing device cannot adjust the storage conditions according to different liquid needs is solved, and efficient and flexible storage of multiple liquids is achieved.
Patent Information
- Application Number
- CN202510609955.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-13
- Publication Date
- 2025-06-20
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing liquid storage devices cannot flexibly adjust the temperature and use of preservation agents according to the storage needs of different liquids, resulting in the inability to effectively store multiple liquids, especially in multiple pathogen detection.
A storage device for detection of multiple pathogens is designed, including an outer box, storage tube, power support, communication hose, a preservation agent release unit, a temperature control unit, a control unit, a monitoring unit and an interactive unit. The target storage plan is determined through the control unit, and the operation of the preservation agent release, temperature control and power support are controlled to achieve personalized preservation of different liquids.
It realizes flexible storage of multiple liquids, improves the storage effect and efficiency, avoids liquid deterioration and condensation, and meets the needs of multiple pathogen detection.
Smart Images

Figure CN120171929A_ABST
Abstract
Description
Technical Field
[0001] This specification relates to the field of liquid preservation equipment, and particularly to a preservation device, a control system and a control method for multi-pathogen detection. Background Art
[0002] In terms of multiplex detection, since the detection signal comes from surface probes, and because the physical position of the surface probes themselves can be used to distinguish the corresponding target nucleic acids thereon, multiplex detection can be achieved with only one kind of label, without the need for multiple fluorescent agents in traditional multiplex qPCR.
[0003] The limitations of traditional qPCR technology are also reflected in its cumbersome operation steps and large reagent consumption. Since each fluorescent label requires an independent detection channel and a specific optical filter, this not only increases the complexity and cost of the detection instrument, but also may introduce more experimental errors. In addition, in actual operation, multiplex qPCR technology requires precise proportioning and mixing of multiple reagents, which requires a high technical level of experimental personnel and is prone to result deviation due to improper operation.
[0004] When performing multi-pathogen detection, during the preservation and transportation of liquids, corresponding preservation devices are often needed, otherwise they may deteriorate. When ordinary preservation devices preserve liquids, they usually only have the function of low-temperature preservation and cannot control the temperature according to different preserved liquids. For example, when preserving blood with a preservation device, a blood preservative is used to maintain the quality of the blood, and the device automatically flips to relieve blood coagulation. However, on the one hand, such a device or preservative has a relatively single use object and can only preserve a certain type of blood. If it is used to preserve blood with lower preservation requirements, it will waste preservation resources; if it is used to preserve blood with higher preservation requirements, a satisfactory preservation effect cannot be achieved. Summary of the Invention
[0005] One or more embodiments of the present specification provide a preservation device for multi-pathogen detection, including an outer box, a storage tube, a power support, a connecting hose, a preservative release unit, a temperature control unit, a control unit, a monitoring unit, and an interaction unit. The storage tube is configured to hold the target liquid to be preserved, and the storage tube is detachably mounted on the tray of the power support. The power support is configured to drive the storage tube to rotate. The preservative release unit is configured to release the preservative required to preserve the target liquid, and the preservative release unit is connected to the connecting hose. The connecting hose is configured to transfer the preservative released by the preservative release unit to the storage tube. The temperature control unit is configured to adjust the temperature of the preservation environment of the target liquid. The monitoring unit is configured to monitor the monitoring data of the preservation environment of the target liquid. The interaction unit is configured to enable a user to interact with the liquid preservation device. The preservative release unit and the temperature control unit are disposed in the box body of the outer box. The control unit is configured to: determine a target preservation plan for the liquid preservation device to preserve the target liquid; generate target operating parameters of the liquid preservation device based on the target preservation plan; and control at least one of the preservative release unit, the temperature control unit for the liquid, and the power support to operate based on the target operating parameters.
[0006] One or more embodiments of the present specification provide a control system for multi-pathogen detection. The control system is used to control the operation of the liquid preservation device according to any one of the embodiments of the present specification, and includes: a determination module, configured to determine a target preservation plan for the liquid preservation device to preserve the target liquid; a generation module, configured to generate target operating parameters of the liquid preservation device based on the target preservation plan; and a control module, configured to control at least one of the preservative release unit, the temperature control unit for the liquid, and the power support to operate based on the target operating parameters.
[0007] One or more embodiments of the present specification provide a control method for multi-pathogen detection. The control method is applied to the liquid preservation device according to any one of the embodiments of the present specification, and the control method includes: determining a target preservation plan for the liquid preservation device to preserve the target liquid; generating target operating parameters of the liquid preservation device based on the target preservation plan; and controlling at least one of the preservative release unit, the temperature control unit, and the power support to operate based on the target operating parameters.
[0008] The present specification will be further described by way of exemplary embodiments, and these exemplary embodiments will be described in detail through the accompanying drawings. These embodiments are not restrictive, and in these embodiments, the same numbers represent the same structures, where:
[0009] Figure 1Schematic diagram of a preservation device for multi - pathogen detection shown in some embodiments of this specification;
[0010] Figure 2 Module diagram of the control system of a preservation device for multi - pathogen detection shown in some embodiments of this specification;
[0011] Figure 3 Flowchart of a control method for multi - pathogen detection shown in some embodiments of this specification;
[0012] Figure 4 Exemplary flowchart of another control method for multi - pathogen detection shown in some embodiments of this specification;
[0013] Figure 5 Schematic diagram of determining a target preservation plan shown in some embodiments of this specification;
[0014] Figure 6 Exemplary flowchart of another control method for multi - pathogen detection shown in some embodiments of this specification;
[0015] Figure 7 Schematic diagram of an effect evaluation model shown in some embodiments of this specification.
[0016] In the figure:
[0017] 100, preservation device for multi - pathogen detection; 110, outer box; 111, working area; 112, side wall;
[0018] 120, storage tube; 130, connecting hose; 140, power support; 141, tray; 150, anti - backflow valve;
[0019] 160, temperature control unit; 170, preservation agent release unit; 180, control unit;
[0020] 200, control system; 210, determination module; 220, generation module; 230, control module;
[0021] 510, initial visual data; 520, initial pH data; 530, liquid information; 540, index evaluation model;
[0022] 541, first embedding layer; 542, initial visual feature; 543, first evaluation layer; 550, preservation requirement;
[0023] 560, initial liquid index; 570, scheme database; 580, target preservation plan;
[0024] 710, Visual data sequence; 720, Current storage scheme; 730, Environmental data sequence; 740, Status data sequence; 750, Effect evaluation model; 751, Second embedding layer; 752, Visual feature sequence; 753, Effect evaluation layer; 760, Current storage effect. Detailed implementation manners
[0025] To more clearly illustrate the technical solutions of the embodiments of this specification, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the drawings in the following description are only some examples or embodiments of this specification. For those of ordinary skill in the art, without creative efforts, this specification can also be applied to other similar scenarios based on these drawings. Unless obvious from the language context or otherwise stated, the same reference numerals in the drawings represent the same structure or operation.
[0026] It should be understood that the "system", "device", "unit" and / or "module" used herein is a method for distinguishing different components, elements, parts, portions or assemblies at different levels. However, if other words can achieve the same purpose, the said words can be replaced by other expressions.
[0027] As shown in this specification and the claims, unless the context clearly indicates an exceptional situation, words such as "a", "an", "one" and / or "the" are not specifically singular and may also include plural. Generally speaking, the terms "include" and "comprise" only indicate the inclusion of the clearly identified steps and elements, and these steps and elements do not constitute an exclusive list. The method or device may also include other steps or elements.
[0028] Flowcharts are used in this specification to illustrate the operations performed by the systems according to the embodiments of this specification. It should be understood that the operations before or after do not necessarily need to be executed precisely in sequence. On the contrary, they can be executed in reverse order or simultaneously. At the same time, other operations can also be added to these processes, or one or several operations can be removed from these processes.
[0029] A liquid is an amorphous state of matter, and its properties are often related to the container. For certain special liquids, both the storage method and the storage container have a greater impact on the properties of the liquid. Taking blood as an example, when it is stored, a blood preservative can be used to maintain the quality of the blood, or a device with a flipping function can be used. However, such a device or preservative has a relatively single object of use and can only store a certain type of blood for a certain purpose.
[0030] Therefore, some embodiments of this specification specifically determine the storage schemes corresponding to various liquids for the storage device for multi-pathogen detection, and safely and efficiently realize the storage and transportation of liquids.
[0031] Figure 1 It is a schematic diagram of a preservation device for multi-pathogen detection shown in some embodiments of this specification.
[0032] As Figure 1 shown, the preservation device 100 for multi-pathogen detection may include an outer box 110, a storage tube 120, a connecting hose 130, a power support 140, a temperature control unit 160, a preservative release unit 170, and a control unit 180.
[0033] The storage tube 120 can be used to hold the target liquid to be preserved. Among them, the target liquid may refer to the liquid to be preserved. For example, the target liquid may include blood (such as whole blood), liquid drugs, liquid biological products, etc.
[0034] In some embodiments, the storage tube 120 is detachably mounted on the tray 141 of the power support 140. In some embodiments, the tube wall of the storage tube 120 can be made of a transparent material (such as glass or transparent plastic) to facilitate the sensor to monitor the state of the target liquid in the storage tube 120.
[0035] As Figure 1 shown, both ends of the storage tube 120 are connected with the connecting hose 130, and the rest can be kept in a sealed state during transportation to avoid the target liquid from being contaminated and oxidized.
[0036] In some embodiments, one or more interfaces can be provided on the storage tube 120. The aforementioned one or more interfaces include an access interface for the target liquid, an entry interface for the preservative, etc. The number of interfaces on the storage tube 120 can be one, and the external structure (such as the connecting hose 130, the injection device, and the extraction device, etc.) can be detachably connected to this interface. For example, when used for preservation, it can be connected to the interface of the storage tube 120 through the connecting hose 130 with a non-return valve 150; when it is necessary to inject and extract the target liquid, it can be replaced with a corresponding injection device or extraction device (for example, through a conversion interface to achieve the injection and extraction of the target liquid) and connected to the interface of the storage tube 120. The aforementioned injection device and extraction device respectively refer to the devices for pumping out and pressing the target liquid into the storage tube 120.
[0037] The outer box 110 can be used to form a working area 111 for liquid preservation. As Figure 1As shown, the storage tube 120, the connecting hose 130, and the power support 140 can be arranged in the working area formed by the outer box 110 so as to adjust the states of the storage tube 120, the connecting hose 130, and the power support 140 during use. The temperature control unit 160, the preservative release unit 170, and the control unit 180 can be arranged in the side wall 112 of the outer box 110 to prevent collisions between various structures when the preservative device 100 for multi-pathogen detection moves.
[0038] In some embodiments, the outer box 110 can refer to a load-bearing container with a certain strength, stiffness, and specifications that can be reused. For example, the outer box 110 can be a container with a size of 20 cm * 20 cm * 20 cm made of stainless steel with a strength grade greater than 10. The outer box 110 can be portable, facilitating the turnover and storage of the target liquid.
[0039] As Figure 1 shown, the power support 140 can be installed on the bottom inside the outer box 110.
[0040] The power support 140 can drive the storage tube 120 to rotate.
[0041] In some embodiments, the power support 140 can include a tray 141 and a driving device (not shown in the figure) for driving the tray to rotate. The tray 141 can be used to fix the storage tube 120, and the storage tube 120 can rotate around the power support 140 according to preset power parameters under the drive of the driving device to shake the target liquid in the storage tube 120 to prevent precipitation and condensation of the components of the target liquid and keep the components in the target liquid evenly dispersed. The rotation parameters can include at least one of the preset rotation amplitude, rotation frequency, rotation duration, rotation speed, rotation direction, etc. The rotation direction can refer to the up-and-down swing of the storage tube 120 around the power support 140 as Figure 1 shown. The aforementioned rotation direction can also be other directions. For example, it can rotate horizontally on a certain plane.
[0042] The preservative release unit 170 can be used to store and release the preservative of the target liquid. The type of the preservative can vary with the target liquid. The preservative can be an additive that prevents or delays the deterioration of the target liquid during storage. For example, when the target liquid is blood, the preservative can include heparin, ethylenediaminetetraacetic acid (EDTA), and citric acid, etc. Before the target liquid collection work, the corresponding type of preservative can be deposited in the preservative release unit 170 in advance.
[0043] The connecting hose 130 can transmit the preservative released by the preservative release unit 170 to the storage tube 120.
[0044] The preservative release unit 170 can be respectively installed on both sides of the outer box 110 and communicated with the connecting hose 130 through a preservative outlet (not shown in the figure) for releasing the preservative. In some embodiments, a valve (not shown in the figure) can be provided on the preservative outlet of the preservative release unit 170. The preservative release unit 170 can be connected to the free end of the connecting hose 130 through the valve. The free end of the connecting hose 130 can refer to the end far from the storage tube.
[0045] The preservative release unit 170 can control the valve through preservation parameters to adjust the opening frequency of the valve, the duration of each opening, etc. Among them, the aforementioned valve can include at least one of a shut-off valve, a check valve, a regulating valve, etc. For more content about the preservation parameters, reference can be made to Figure 3 and its related descriptions.
[0046] In some embodiments, the preservation device 100 for multi-pathogen detection can release the preservative through the preservative release unit 170, and the aforementioned preservative can enter the storage tube 120 through the connecting hose 130. The preservation device 100 for multi-pathogen detection controls the rotation of the storage tube 120 through the power support 140 to evenly disperse the preservative in the storage tube 120 and prevent the target liquid from condensing.
[0047] When disassembling the storage tube 120, the connection between the connecting hose 130 and the valve on the preservative release unit 170 is disassembled to separate the storage tube 120 and the outer box 110, so as to inject the collected target liquid into the storage tube 120 or transfer the target liquid to other storage environments.
[0048] As Figure 1 shown, an anti-backflow valve flap 150 can also be provided at one end of the connecting hose 130 close to the storage tube 120. The anti-backflow valve flap 150 can be used to prevent the target liquid from flowing into the connecting hose 130 from the storage tube 120. That is, the preservative released by the preservative release unit 170 can flow into the storage tube 120, but the target liquid in the storage tube cannot flow into the connecting hose 130, thereby preventing the target liquid in the storage tube 120 from flowing back into the connecting hose 130 when the target liquid in the storage tube 120 is shaken through the power support 140 or the preservation device 100 for multi-pathogen detection is moved.
[0049] The temperature control unit 160 can be used to adjust the temperature of the storage environment of the target liquid in the preservation device 100 for multi-pathogen detection. The storage environment may refer to the environment where the working area 111 is located inside the outer box. The temperature control unit 160 may include a refrigerant, an electric compressor, a condenser, etc. Exemplarily, after the liquid refrigerant passes through a channel (not shown in the figure) provided in the side wall of the outer box 110, it can vaporize to absorb heat, reducing the temperature of the storage environment. The generated vapor after vaporization is then compressed by the electric compressor into the condenser for liquefaction, and the heat brought out from inside the outer box 110 is released through the channel in the side wall of the outer box 110. By circulating the refrigerant inside the outer box 110, the inside of the outer box 110 can be maintained at a relatively low temperature.
[0050] The aforementioned temperature control unit 160 can adjust the parameters of its internal structure (such as the dosage of the refrigerant, the power of the electric compressor and the condenser, etc.) through temperature control parameters to control the temperature inside the outer box 110. For more content about the temperature control parameters, reference can be made to Figure 3 and its related description.
[0051] The interaction unit (not shown in the figure) can be a device for the user to interact with the liquid preservation device (the preservation device 100 for multi-pathogen detection). For example, the user can control the opening and closing of the liquid preservation device through the interaction unit. For another example, the interaction unit can also be used to receive data input by the user (such as the liquid information of the target liquid). For more content about the liquid information, reference can be made to Figure 3 and its related description.
[0052] The user refers to the person related to the liquid preservation device. For example, the user can be a manager or an operator, etc.
[0053] In some embodiments, the interaction unit can be installed on the preservation device 100 for multi-pathogen detection or independent of the preservation device 100 for multi-pathogen detection. The user can directly interact with the preservation device 100 for multi-pathogen detection through the interaction unit. For example, the interaction unit can include one or more of a display screen, buttons, touch sensors, keyboards, microphones, etc. installed on the preservation device 100 for multi-pathogen detection. The interaction unit can also be connected to the user terminal through a network, and the user can interact with the interaction unit through the user terminal.
[0054] In some embodiments, the liquid preservation device may further include a monitoring unit (not shown in the figure).
[0055] The monitoring unit can be a device for monitoring the monitoring data of the storage environment. The aforementioned monitoring data may include environmental data, status data, etc. In some embodiments, the monitoring unit may include an environmental monitoring sub-unit, a status monitoring sub-unit, etc.
[0056] The environmental monitoring subunit can be used to monitor the environmental data of the storage environment. The environmental data can refer to the data related to the storage environment in which the liquid storage device stores the target liquid during the current time period. In some embodiments, the environmental data can include at least one of air pressure data, temperature data, and vibration data. Correspondingly, the environmental monitoring subunit can include sensors for obtaining the foregoing environmental data. For example, when the environmental data includes air pressure data, the environmental monitoring subunit can include an air pressure sensor for monitoring the tightness of the storage environment; when the environmental data includes temperature data, the environmental monitoring subunit can include a temperature sensor for monitoring the temperature of the storage environment; when the environmental data includes vibration data, the environmental monitoring subunit can include a vibration sensor for monitoring the vibration condition of the target liquid.
[0057] The status monitoring subunit can be used to monitor the status data of the target liquid. The status data can refer to the data related to the status in which the liquid storage device stores the target liquid during the current time period. In some embodiments, the status data can include at least one of pH data and visual data. Correspondingly, the status monitoring subunit can include sensors for obtaining the foregoing status data. For example, when the status data includes pH data, the status monitoring subunit can include a pH sensor for monitoring the pH value of the target liquid; when the status data includes visual data, the status monitoring subunit can include a visual sensor (such as a camera, a video camera, etc.) for monitoring the transparency, condensation condition, etc. of the target liquid.
[0058] For more information about environmental data and status data, please refer to Figure 6 and its related descriptions.
[0059] The control unit 180 can be used to manage resources and process data and / or information from the multi-pathogen detection storage device 100 or an external data source (such as a cloud data center). The control unit 180 can be communicatively connected to the power support 140, the preservative release unit 170, the temperature control unit 160, the monitoring unit, and the interaction unit. The control unit 180 can obtain data and / or information from the interaction unit, the monitoring unit, etc. in the multi-pathogen detection storage device 100, and execute program instructions based on these data, information, and / or processing results to perform one or more functions described in the embodiments of this specification.
[0060] In some embodiments, the control unit 180 can determine the target storage scheme for the multi-pathogen detection storage device 100 to store the target liquid; based on the target storage scheme, generate the target operating parameters of the multi-pathogen detection storage device 100, and based on the target operating parameters, control at least one of the preservative release unit 170, the temperature control unit 160, and the power support 140 to operate. For more information about the above embodiments, please refer toFigure 3 and its related descriptions.
[0061] The control unit 180 can be a system with computing capabilities, such as a computer, an industrial control computer, a computing cloud platform, etc. In some embodiments, the control unit may include one or more sub-processors. For example, a central processing unit (CPU), a digital signal processor (DSP), a field programmable gate array (FPGA), a microprocessor, etc., or any combination thereof. In some embodiments, the control unit 180 may include a communication sub-unit, a control sub-unit, and a remote processor. The communication sub-unit may refer to a device with network access capabilities. For example, the communication sub-unit can communicate with a user terminal and a remote processor in a wired, wireless, or other manner. The remote processor may refer to a remote processor. For example, a cloud server, etc.
[0062] In some embodiments, the preservation device 100 for multi-pathogen detection may further include other structures. For example, the liquid preservation device further includes a storage device, and the control unit can obtain pre-stored data and / or information related to the preservation device 100 for multi-pathogen detection from the storage device. For another example, the preservation device 100 for multi-pathogen detection may further include components of a network and / or other connection systems to external resources. The control unit 180 can obtain data and / or information related to the liquid preservation device through the network.
[0063] In some embodiments described in this specification, the liquid preservation device can determine a target preservation scheme to control the operation of at least one of the preservative release unit, the temperature control unit, and the power support, so that the liquid preservation device is maintained in a suitable preservation condition and environment, improving the preservation effect and efficiency of the target liquid.
[0064] Figure 2 Module diagram of the control system of the preservation device for multi-pathogen detection shown according to some embodiments of this specification. As Figure 2 shown, the control system 200 of the liquid preservation device may include a determination module 210, a generation module 220, and a control module 230.
[0065] The determination module 210 can be used to determine a target preservation scheme for the liquid preservation device to preserve the target liquid.
[0066] In some embodiments, the determination module 210 can also be used to receive, through the interaction unit, the liquid information of the target liquid input by the user, and based on the liquid information, determine a target preservation scheme for the liquid preservation device to preserve the target liquid.
[0067] In some embodiments, the determination module 210 may further be configured to obtain environmental data through the environmental monitoring subunit, where the environmental data includes at least one of barometric pressure data, temperature data, and vibration data; obtain status data through the status monitoring subunit, where the status data includes at least one of pH data and visual data. The determination module 210 may further be configured to: obtain an initial preservation plan for preserving the target liquid by the liquid preservation device during a current time period; and determine the target preservation plan during a target time period based on the environmental data, the status data, and the initial preservation plan.
[0068] The generation module 220 may be configured to generate target operating parameters of the liquid preservation device based on the target preservation plan; The control module 230 may be configured to control the operation of at least one of the preservative release unit, the temperature control unit liquid, and the power support based on the target operating parameters.
[0069] It should be noted that the above description of the control system 200 of the liquid preservation device and its modules is only for convenience of description and does not limit this specification to the scope of the exemplified embodiments. It can be understood that for those skilled in the art, after understanding the principle of the system, they may, without departing from this principle, make any combination of the modules, or form a subsystem and connect it with other modules. In some embodiments, Figure 2 the determination module 210, the generation module 220, and the control module 230 disclosed in may be different modules in a system, or a single module may implement the functions of two or more of the above modules. For example, the modules may share a storage module, or each module may have its own storage module. Such variations are all within the protection scope of this specification.
[0070] Figure 3 is a flowchart of a control method for multi-pathogen detection according to some embodiments of this specification. In some embodiments, Figure 3 the control method for liquid preservation shown may be executed by a control unit. As Figure 3 shown, the control method includes the following steps:.
[0071] Step 310, determine a target preservation plan for the liquid preservation device to preserve the target liquid.
[0072] The target preservation scheme can refer to the preservation scheme applicable to the liquid preservation device for preserving the target liquid within the target time period. The target time period can be the entire preservation cycle for the liquid preservation device to preserve the target liquid, or it can be the next sub-time period for the liquid preservation device to preserve the target liquid. The control unit can divide the preservation cycle into multiple sub-time periods. For example, from 8:00 to 12:00 on a certain day, the liquid preservation device needs to preserve the target liquid. The control unit can divide the aforementioned preservation cycle into 4 cycles with one hour as a unit. If the current time is 8:30 on this day, the current time period for the liquid preservation device to preserve the target liquid is the first sub-time period, and the next time period is from 9:00 to 12:00. The control unit can execute process 200 at the end of each sub-time period to determine the target preservation scheme for the target time period.
[0073] The target preservation scheme can include at least one of a preservative release scheme, a liquid sloshing scheme, a temperature control scheme, etc.
[0074] The preservative release scheme refers to the relevant requirements for the preservative when the liquid preservation device preserves the target liquid within the target time period. For example, the preservative release scheme can include, but is not limited to, the release time point, release frequency, and amount of each release of the preservative within the target time period.
[0075] The liquid sloshing scheme can refer to the requirement for liquid sloshing, corresponding to the operating parameters of the dynamic support. For example, the liquid sloshing scheme can include the sloshing frequency of the target liquid, as well as the sloshing amplitude, sloshing speed, and sloshing duration during each sloshing.
[0076] The temperature control scheme can refer to the requirement for temperature, corresponding to the operating parameters of the temperature control unit. For example, the temperature control scheme can include the temperature requirement during preservation (for example, a constant temperature value).
[0077] The target preservation scheme can be represented in the form of a vector. For example, a certain target preservation scheme can be represented as [(a, b, c), (d, e), (f, g)], where the three elements of this target preservation scheme respectively represent the preservative release scheme, the liquid sloshing scheme, and the temperature control scheme, and the values of the elements represent the corresponding preservation requirements. Exemplarily, the preservative release scheme can be represented as (a, b, c), where a represents the preservative release time point, b represents the release frequency, and c represents the amount of each release; the liquid sloshing scheme can be represented as (d, e), where d represents the sloshing frequency of the liquid, and e represents the sloshing amplitude, speed, and duration during each sloshing; the temperature control scheme can be represented as (f, g), where f represents the standard temperature, and g represents the allowable temperature fluctuation range.
[0078] The target storage scheme can be determined in various ways. For example, the control unit can obtain the liquid type of the target liquid and determine the corresponding target storage scheme by querying the preset table of liquid type and storage scheme. For more information about the liquid type, refer to Figure 4 and its related descriptions.
[0079] In some embodiments, the control unit can determine the target storage scheme for the liquid storage device to store the target liquid based on the liquid information of the target liquid.
[0080] The liquid information can refer to the information related to the target liquid by the liquid storage device within the target time period. For example, the liquid information can include but is not limited to the collector information, liquid type, liquid volume, liquid use, etc., or any combination thereof.
[0081] The collector information can include the relevant information of the collector, where the collector is the collection object of the target liquid. For example, the collector information can include the gender, age, important medical history, etc. of the collector. The liquid type can include red blood cell products, plasma, platelets, cryoprecipitate, etc. The liquid use can include uses such as testing and storage. The collector can refer to the person from whom the target liquid is collected.
[0082] The liquid information can be obtained in various ways. In some embodiments, the control unit can obtain liquid information such as liquid type and liquid use through the interaction unit. For example, when collecting the target liquid, the interaction unit can display text information asking the user about the liquid information on the display screen, and / or play the text information asking the user about the liquid information through the speaker to guide the user to feedback the liquid information.
[0083] In some embodiments, the control unit can perform modeling or adopt various data analysis algorithms, such as regression analysis method, discriminant analysis method, etc., to analyze and process the liquid information to determine the target storage scheme. The control unit can determine the liquid storage requirements based on the liquid type and liquid use; according to the storage requirements, select the target storage scheme. Different liquid types and different liquid uses correspond to different liquid storage requirements, and different liquid storage requirements correspond to different target storage schemes.
[0084] The storage requirements can refer to the requirements for the storage environment when the liquid storage device stores the target liquid within the target time period to achieve a better storage effect. For example, the storage requirements can include at least one requirement for the preservative, liquid shaking, temperature, etc.
[0085] In some embodiments of the present specification, the control unit determines a target preservation scheme based on liquid information, which can make the target preservation scheme more suitable for actual requirements, avoid damage to the target liquid components caused by too high or too low temperatures, and avoid severe vibration or shock to the storage tube, thereby improving the effect and quality of liquid preservation.
[0086] In some embodiments, the control unit may determine the preservation requirements of the target liquid based on the liquid information; and determine the target preservation scheme for the liquid preservation device to preserve the target liquid based on the preservation requirements. For more content about this embodiment, refer to Figure 4 and its related descriptions.
[0087] In some embodiments, the control unit may also obtain the current preservation scheme of the liquid preservation device for preserving the target liquid during the current time period; and determine the target preservation scheme for the target time period based on the environmental data, status data, and the current preservation scheme. For more content about this embodiment, refer to Figure 6 and its related descriptions.
[0088] Step 320: Generate the target operating parameters of the liquid preservation device based on the target preservation scheme.
[0089] The target operating parameters refer to the parameters adopted by each component in the liquid preservation device when preserving the target liquid during the target time period. The target operating parameters may include the preservation parameters of the preservative release unit, the temperature control parameters of the temperature control unit, the power parameters of the power support, etc., or any combination thereof.
[0090] The preservation parameters refer to the parameters adopted by the preservative release unit during the target time period. For example, the preservation parameters may include, but are not limited to, one or more of the opening frequency of the preservative release unit during the target time period, the duration of each opening, etc. Among them, the aforementioned opening duration can be used to reflect the dose of the preservative released each time.
[0091] The temperature control parameters refer to the parameters adopted by the temperature control unit during the target time period. For example, the temperature control parameters may include the condenser power, etc.
[0092] The power parameters refer to the parameters adopted by the power support during the target time period. For example, the power parameters may include, but are not limited to, the time interval of the power support rotation, the rotation amplitude of each rotation, the rotation speed, the rotation duration, etc.
[0093] The control unit may analyze and process the target preservation scheme and the environmental data of the liquid preservation device during the current time period to determine the corresponding target operating parameters. For more content about the environmental data, refer to Figure 4 and its related descriptions.
[0094] By way of example only, in the temperature control scheme, the temperature required for heat preservation is 6°C, while the environmental data indicates that the temperature in the storage environment during the current time period is 8°C. The control unit can determine the temperature control parameters of the temperature control unit based on the difference between the temperature required for heat preservation and the temperature during the current time period, so that the temperature control unit adjusts the temperature of the storage environment to 6°C within the target time period.
[0095] Step 330, based on the target operating parameters, control at least one of the preservative release unit, the temperature control unit, and the power support to operate.
[0096] In some embodiments, the control unit can issue at least one set of control instructions to at least one of the preservative release unit, the temperature control unit, and the power support based on the target operating parameters. The liquid storage device can operate based on the aforementioned at least one set of control instructions within the target time period to store the target liquid in a suitable environment.
[0097] In some embodiments of the present specification, the control unit can determine the target storage scheme, and through the target storage scheme, determine the target operating parameters within the target time period, so as to control at least one of the preservative release unit, the temperature control unit, and the power support to operate within the target time period, which can keep the liquid storage device in a suitable environment, improve the storage effect of the target liquid, and prevent the target liquid from deteriorating (e.g., coagulating).
[0098] Figure 4 is an exemplary flowchart of another control method for multi-pathogen detection shown in some embodiments of the present specification. In some embodiments, Figure 4 the control method for liquid storage shown can be executed by the control unit. As Figure 4 shown, this control method includes the following steps: Step 410, based on the liquid information, determine the storage requirements of the target liquid.
[0099] The storage requirements refer to the environmental conditions that need to be met for storing the target liquid in the liquid storage device. The storage requirements can include one or more of the storage duration requirements, the end liquid index requirements (i.e., the requirements for the liquid index of the target liquid at the end of storage), the environmental temperature, etc. For example, when the target liquid is blood, the temperature inside the liquid storage device needs to be controlled between 2°C and 8°C.
[0100] In some embodiments, the control unit can determine the storage requirements of the target liquid by querying a preset table. Different liquid types and liquid uses corresponding to storage requirements are included in the aforementioned preset table, and the preset table can be formulated according to relevant specifications for liquid storage.
[0101] Step 420, based on the storage requirements, determine the target storage scheme for the liquid storage device to store the target liquid.
[0102] The control unit can model or adopt various data analysis algorithms, such as regression analysis method, discriminant analysis method, etc., to analyze and process the preservation requirements, and determine the target preservation plan for the target liquid by the liquid preservation device.
[0103] In some embodiments, the control unit can analyze and process the liquid information, initial pH data, and initial visual data based on the index evaluation model to determine the initial liquid index of the target liquid; and retrieve the preservation plan in the plan library based on the initial liquid index and the liquid preservation requirements. For more content about the above embodiments, reference can be made to Figure 5 and its related description.
[0104] Some embodiments of this specification can more accurately determine the preservation requirements of the liquid by obtaining the liquid information, so that based on the preservation requirements, targeted retrieval can be carried out in the plan database, greatly improving the accuracy of the control unit to determine the target preservation plan of the target liquid.
[0105] Figure 5 is a schematic diagram of determining the target preservation plan shown according to some embodiments of this specification.
[0106] In some embodiments, before determining the target preservation plan, the control unit can enable the index evaluation model to determine the initial liquid index of the target liquid.
[0107] As Figure 5 shown, the control unit can analyze and process the liquid information 530, initial pH data 520, and initial visual data 510 based on the index evaluation model 540 to determine the initial liquid index 560 of the target liquid.
[0108] The initial pH data 520 can refer to the pH data of the target liquid before preservation or at the beginning of preservation.
[0109] The initial visual data 510 can refer to the visual data of the target liquid before preservation or at the beginning of preservation. For example, the initial visual data 510 can include image data of the target liquid before preservation or at the beginning of preservation.
[0110] The initial pH data 520 and the initial visual data 510 can be obtained through the monitoring unit or the interaction unit. For more content about obtaining the initial pH data and the initial visual data through the monitoring unit or the interaction unit, reference can be made to Figure 1 and its related description.
[0111] The initial liquid index 560 can be the liquid index of the target liquid before preservation or at the beginning of preservation. The liquid index can refer to the index related to the biochemical detection of the target liquid during the preservation process of the target liquid. For example, when the target liquid is blood, the initial liquid index 560 can include oxygenation status, enzyme activity, coagulation function, ion balance, hemoglobin, hematocrit, white blood cell count, acid-base balance, etc. or a combination of the above.
[0112] It can be understood that there can be multiple initial liquid indexes of the target liquid, but each initial liquid index can be related to each other. For example, the pH value can characterize the acidity and alkalinity of the target liquid, and the acidity and alkalinity will affect the oxygenation status, enzyme activity, coagulation function, particle balance, etc. At the same time, the visual data of the liquid (such as color, transparency, etc.) will be different due to the change of some initial liquid indexes. Therefore, the control unit can combine the liquid information to evaluate each initial liquid index in the target liquid.
[0113] The index evaluation model 540 can be used to determine the initial liquid index 560 of the target liquid. The index evaluation model 540 can include one or more machine learning models such as a convolutional neural network model, a deep learning model, etc.
[0114] As Figure 5 shown, the input of the index evaluation model 540 can include liquid information 530, initial pH data 520, and initial visual data 510, and the output can include the initial liquid index 560. The index evaluation model 540 can include a first embedding layer 541 and a first evaluation layer 543.
[0115] The first embedding layer 541 can be used to determine the initial visual feature 542 of the target liquid. The initial visual feature 542 can be data reflecting the visual characteristics of the target liquid before preservation or at the beginning of preservation. For example, the initial visual feature 542 can include features such as the color, transparency, etc. of the target liquid before preservation or at the beginning of preservation.
[0116] As Figure 5 shown, the input of the first embedding layer 541 can include the initial visual data 510, and the output can include the initial visual feature 542. The first embedding layer 541 can be a convolutional neural network.
[0117] The first evaluation layer 543 can be used to determine the initial liquid index 560 of the target liquid.
[0118] As Figure 5 shown, the input of the first evaluation layer 543 can include the initial visual feature 542, the initial pH data 520, and the liquid information 530, and the output can include the initial liquid index 560. The first evaluation layer can be a deep learning model.
[0119] In some embodiments, a trained metric evaluation model may be preset in the control unit. The metric evaluation model may be obtained through joint training based on a large number of first training samples with first labels: inputting the sample initial visual data in the first training samples into an initial first embedding layer to obtain sample initial visual features output by the initial first embedding layer, inputting the output of the initial first embedding layer, sample liquid information, and sample initial pH data into an initial first evaluation layer to obtain initial liquid metrics; constructing a loss function based on the output of the initial first evaluation layer and the first labels, and simultaneously updating the parameters of the initial first embedding layer and the parameters of the initial first evaluation layer until a preset condition is met and the training is completed. Among them, the preset condition may be that the loss function is less than a threshold, converges, or the number of training epochs reaches a threshold.
[0120] For each group of first training samples, the first training samples may include sample liquid information, sample initial pH data, and sample initial visual data, and the first labels may include the sample initial liquid metrics corresponding to the first training samples. The first training samples may use the visual initial data, initial pH values, and liquid information of the historical target liquid in the historical data as training samples, and the first labels may be obtained based on manual or automatic annotation. The first labels are determined based on the actual liquid metrics in the historical data. For example, the actual liquid metrics of the sample target liquid in the historical data (metrics accurately measured by instruments, etc.) are used as the first labels.
[0121] It can be understood that due to different collector information in the liquid information, there may be differences in the correlation between the traits of the target liquid and the liquid metrics. For example, the correlation between the traits of the target liquid and the liquid metrics may vary among different populations (age, gender, health status, physiological state, menstrual period, etc.). For example, when the target liquid is blood, there may be differences in some liquid metrics in the blood at different age stages (such as hemoglobin, hematocrit, etc.). Especially in the elderly population, the elderly are more likely to suffer from diseases such as anemia and cardiovascular diseases, and at the same time, liquid metrics such as platelet aggregation and blood clotting time may also change. Another example is that there may be differences in some liquid metrics in the blood of different genders. Liquid metrics such as lactate dehydrogenase, creatine kinase, and testosterone are higher in male blood, while blood metrics such as female estrogen, progesterone, and ovarian hormones may change during the menstrual cycle in females. Another example is that there may be differences in some liquid metrics in the blood of different health statuses. In diseased populations (such as anemia, liver diseases, kidney diseases, etc.), some blood metrics (such as hemoglobin, alanine aminotransferase, aspartate aminotransferase, etc.) may change significantly, so the correlation between the traits of blood and the liquid metrics may be different.
[0122] Therefore, if the information about the initial liquid indicators obtained only through the initial pH data, initial visual data, etc. is relatively limited, some embodiments of this specification can comprehensively evaluate the initial liquid indicators in combination with the liquid information, improving the accuracy of the initial liquid indicators.
[0123] As Figure 5 shown, the control unit can determine the target storage scheme 580 based on the initial liquid indicator 560, the storage requirement 550, and the scheme database 570. For example, the control unit can retrieve in the scheme database 570 based on the initial liquid indicator 560 and the storage requirement 550 to determine the target storage scheme 580.
[0124] The scheme database 570 can refer to a database for storing, indexing, and querying vectors. For example, the scheme database 570 can store multiple reference vectors and their corresponding associated vectors. The reference vector refers to a vector composed of historical initial liquid indicators, historical storage requirements, etc.; the associated vector refers to a vector composed of the historical target storage scheme corresponding to the historical initial liquid indicator and the historical storage requirement.
[0125] In some embodiments, a retrieval vector can be generated based on the initial liquid indicator 560 and the storage requirement 550, and retrieved in the scheme database 570 based on the retrieval vector to determine the reference vector that meets the matching conditions, determine the reference vector that meets the matching conditions as the target vector, and determine the historical target storage scheme corresponding to the target vector as the target storage scheme. Among them, the matching condition can refer to the judgment condition for determining the target vector. The matching condition can include that the vector distance from the retrieval vector is less than the distance threshold, the vector distance is the smallest, etc. There are various methods for calculating the vector distance, such as Euclidean distance, cosine distance, Mahalanobis distance, Chebyshev distance, Manhattan distance, etc.
[0126] Through the vector database, similarity queries and other vector management can be quickly performed on a large number of vectors. The aforementioned vector database can be stored in the liquid storage device. The vector database can also be set independently of the liquid storage device. The control unit can send the initial liquid indicator 560 and the storage requirement 550 to the vector database, and the processor associated with the vector database can perform the retrieval, determine the target storage scheme 580, and feedback it to the control unit.
[0127] In some embodiments of this specification, by using the index evaluation model to determine the initial liquid indicators, the accuracy and efficiency of determining the initial liquid indicators can be improved by using a machine learning model; by establishing a scheme database based on historical data and retrieving in the scheme database, a reasonable target storage scheme can be obtained relatively quickly.
[0128] When the target time period is the next sub - time period for the liquid storage device to store the target liquid, the control unit can pass through Figure 6The control method for liquid storage shown continuously obtains the relevant data of the current liquid storage device for storing the target liquid, so as to determine the next sub-time period, that is, the target storage plan within the target time period. When in the first sub-time period of the storage cycle, the control unit can also determine the current storage plan for the current time period in other ways. For example, execute Figure 4 The control method for liquid storage shown is determined.
[0129] Figure 6 It is an exemplary flowchart of another control method for multi-pathogen detection shown according to some embodiments of this specification. In some embodiments, Figure 6 The control method for liquid storage shown can be executed by the control unit. As Figure 6 shown, this control method includes the following steps:
[0130] Step 610, obtain the current storage plan of the liquid storage device for storing the target liquid within the current time period.
[0131] The current storage plan may refer to the storage plan of the liquid storage device for storing the target liquid in the current time period. The current time period may be the sub-time period corresponding to the current time in the storage cycle. For example, if the current time is 8:30, the current time period may be 8:00 - 9:00.
[0132] The target time period refers to the next sub-time period after the current time period in the storage cycle.
[0133] In some embodiments, the control unit can determine the current storage plan in various ways. For example, the control unit can determine the previously determined target storage plan as the current storage plan. For another example, obtain the current storage plan from the storage device.
[0134] Step 620, based on the environmental data, status data, and current storage plan within the current time period, determine the target storage plan within the target time period.
[0135] In some embodiments, the control unit can determine the status data of the target liquid within the current time period through the status monitoring subunit. For more information about the status monitoring subunit, reference can be made to Figure 1 and its related description.
[0136] In some embodiments, the control unit can determine the environmental data of the storage environment within the current time period through the environmental monitoring subunit. For more information about the environmental monitoring subunit, reference can be made to Figure 1 and its related description.
[0137] In some embodiments, the control unit may determine whether to adjust the current preservation scheme based on the monitoring data and the liquid information; in response, based on the change values of the monitoring data and the liquid information, adjust the current preservation scheme to determine the target preservation scheme.
[0138] In some embodiments, the control unit may determine whether at least one of the monitoring data and the liquid information changes within the current time period. For example, the control unit may compare the monitoring data at multiple time points within the current time period to determine whether the change value of the monitoring data exceeds a preset threshold. For example, whether the change value of the ambient temperature exceeds 0.1°C.
[0139] In some embodiments, the control unit may adjust the current preservation scheme in various ways based on the change values of the monitoring data and the liquid information to determine the target preservation scheme within the target time period. For example, the control unit may establish a preset table based on the relationship between the change values of the monitoring data, the liquid information, and the change value of the preservation scheme in the historical data, and determine the change value of the preservation scheme by looking up the table based on the change values of the monitoring data and the liquid information, so as to adjust the current preservation scheme to obtain the target preservation scheme.
[0140] In some embodiments, the control unit may determine the current preservation effect of the current preservation scheme based on the environmental data and the status data within the current time period.
[0141] The current preservation effect may be used to indicate the effect of the liquid preservation device on preserving the target liquid within the current time period. For example, the current preservation effect may be characterized by a numerical value from 0 to 100, and the higher the numerical value, the better the preservation effect in the current time period.
[0142] In some embodiments, the current preservation effect may be determined by analyzing the change values of the pH data and the visual data of the target liquid within the current time period and the pH data and the visual data in the previous time period. When the current time period is the first sub-time period of the preservation cycle, the aforementioned pH data and visual data in the previous time period may be the initial pH data and the initial visual data of the target liquid. For more information about the initial pH data and the initial visual data, please refer to Figure 5 and its related descriptions.
[0143] In some embodiments, the current preservation effect may also be determined by analyzing the change values of the various liquid indicators of the target liquid within the current time period and the liquid indicators in the previous time period. When the current time period is the first sub-time period of the preservation cycle, the aforementioned liquid indicators in the previous time period may be the initial liquid indicators of the target liquid. For more information about the initial liquid indicators, please refer to Figure 5 and its related descriptions.
[0144] In some embodiments, the control unit can also determine the preservation effect of the current preservation scheme through an effect evaluation model based on the initial liquid index, the current preservation scheme, and the environmental data sequence and status data sequence corresponding to the current preservation scheme. For more content about this embodiment, reference can be made to Figure 7 and its related descriptions.
[0145] In some embodiments, when the current preservation effect meets a preset condition, the control unit can adjust the current preservation scheme based on the current preservation effect, determine a target preservation scheme, and send an alarm message to the user. The preset condition can be a judgment condition related to evaluating whether to adjust the current preservation scheme and the preservation effect. When the current preservation effect meets the preset condition, it indicates that the current preservation scheme cannot meet the preservation requirements and needs to be adjusted; when the current preservation effect does not meet the preset condition, it indicates that the current preservation scheme can meet the preservation requirements and does not need to be adjusted.
[0146] The preset condition can be that the current preservation effect is lower than a preset effect threshold, where the preset effect threshold can be determined based on the initial liquid index, the final liquid index, and the preservation period. For example, the control unit can determine the acceptable change values of each liquid index of the target liquid in each sub-time period within the preservation period based on the initial liquid index, the final liquid index, and the preservation period, so as to determine the preset effect threshold based on the foregoing change values. Exemplarily, taking a certain liquid index as an example, when the target value of a certain liquid index is m, the initial value is n, and the required preservation duration is t, the acceptable change value of each sub-time period is (n - m) / t, and thus the corresponding preset effect threshold can be determined.
[0147] For a target liquid placed normally in the external environment, its corresponding liquid indicators may deteriorate over time. Taking the target liquid as blood for example, due to different storage environments, such as changes in oxygen content, temperature, pH value, etc., the oxygenation state of blood may change; the partial pressure of oxygen in blood will decrease over time; various enzymes in blood may become inactivated or degraded during in vitro storage, resulting in changes in enzyme activity; the oxidase activity of hemoglobin will decrease over time; due to biological and chemical changes in the blood coagulation mechanism during blood storage, rare blood clots may be induced; when the pH value of the blood to be stored is unstable and the ion concentration changes, etc., it will affect the normal metabolic activities of cells in the blood, the integrity of the cell membrane and other related physiological functions; the hemoglobin value begins to decrease after 24 hours of storage and decreases significantly after 48 hours, possibly reaching less than half; the hematocrit will decrease with the extension of storage time and is irreversible; the white blood cell count will gradually decrease with the increase of storage time; the pH value of the blood to be stored will change with the increase of time. If the blood contains components of alveolar blood gas, the pH value will drop rapidly on the first day of storage. Intracellular metabolism will continue in vitro, the carbon dioxide concentration will rise, causing respiratory acidosis.
[0148] Therefore, the various liquid indicators of the target liquid may not change at a uniform speed. Correspondingly, the preset effect threshold may not be a fixed value either. In some embodiments, the preset effect thresholds for each sub-time period of the storage cycle may be different, and their specific values can be analyzed and determined according to the changes of various liquid indicators in the target liquid over time, so that the analysis of the current storage effect by the control unit conforms to the actual situation to ensure the accuracy and reliability of the target liquid during clinical application.
[0149] When the current storage effect meets the preset conditions, the control unit can adjust at least one of the current preservative release scheme, the current liquid shaking scheme, and the current temperature control scheme in the current storage scheme, so that the storage effect corresponding to the adjusted current storage scheme meets the storage requirements. For example, adjust the release time point, release frequency, and each release amount of the preservative. For another example, adjust the shaking frequency of the target liquid, as well as the shaking amplitude, shaking speed, and shaking duration each time when shaking. For another example, adjust the temperature requirements during storage.
[0150] In some embodiments, the control unit can determine the target storage scheme through various methods based on the current storage effect. For example, the control unit can determine the target storage scheme by using various methods such as manual analysis, theoretical calculation, and / or modeling based on the current storage effect. For example, based on the current storage effect, it can be analyzed and determined that the current storage effect does not meet the storage requirements, and then a suitable target storage scheme can be determined according to historical experience.
[0151] In some embodiments, when the current preservation effect meets the preset conditions, the control unit may compare the environmental data with the standard environmental data to determine the cause of the abnormality of the current preservation effect.
[0152] The standard environmental data may be preset environmental data suitable for preserving the target liquid. The standard environmental data may include standard air pressure data, standard temperature data, standard vibration data, etc. The standard environmental data may be related to the liquid type.
[0153] The cause of the abnormality may refer to the reasons that may cause the abnormality of the current preservation effect. For example, the cause of the abnormality may include temperature abnormality, airtightness abnormality, vibration abnormality, etc.
[0154] In some embodiments, when the current preservation effect meets the preset conditions, the control unit may compare the environmental data with the standard environmental data and determine the cause of the abnormality based on the comparison result. For example, when the temperature data in the current time period is different from the standard temperature data, the temperature control unit adjusts the temperature data at the current moment; when the vibration data in the current time period is different from the standard vibration data, the dynamic support adjusts the vibration data at the current moment.
[0155] For each cause of the abnormality, the control unit may make targeted adjustments to reduce the negative impact brought by the abnormality.
[0156] In some embodiments of this specification, by adjusting the cause of the abnormality to determine the target preservation plan, the current preservation plan can be adjusted in a targeted manner, improving the efficiency and accuracy of the adjustment.
[0157] The alarm information may be a risk reminder that may occur during the liquid preservation process. The alarm information may include one or more of voice signals, light color signals, and character signals. For example, when the expected preservation effect meets the preset conditions, the control unit may send out alarm information to notify the user to check the liquid preservation device.
[0158] When the current preservation effect meets the preset conditions, the control unit may adjust the corresponding operating parameters in the current preservation plan based on the cause of the abnormality to determine the target preservation plan. For example, when the vibration is too intense, the rotation frequency, rotation speed, rotation amplitude, rotation duration, etc. of the dynamic support are reduced; when the temperature is too high, the temperature of the preservation environment is appropriately reduced.
[0159] In some embodiments of the present specification, by evaluating and judging the current preservation effect, and then timely adjusting the current preservation plan to determine the target preservation plan for the next sub-time period, the liquid preservation device can dynamically evaluate the preservation effect of the target liquid, and continuously adjust the preservation plan based on it, so that the preservation of the target liquid is more in line with the actual situation, and the correspondence between the operating parameters and the real-time situation of the target liquid is better, thereby improving the liquid preservation effect.
[0160] It should be noted that the liquid preservation device can, in the first sub-time period after startup, determine the preservation plan for this sub-time period by executing Figure 4 the control method of liquid preservation shown. In each other sub-time period after startup, the liquid preservation device monitors the preservation effect of the current preservation plan in real time, and when its preservation effect meets the preset conditions, adjusts the current preservation plan to obtain the target preservation plan for the target time period.
[0161] In some embodiments of the present specification, by using environmental data, status data, and the current preservation plan to determine the target preservation plan within the target time period, a suitable liquid preservation environment with appropriate temperature and vibration can be provided for the liquid preservation device, avoiding damage to blood components caused by too high or too low temperature, or simultaneously avoiding the situation where the target liquid is violently vibrated and blood coagulation occurs, thereby improving the quality of liquid preservation.
[0162] It should be noted that the above descriptions of the various processes are only for illustration and explanation, and do not limit the scope of application of the present specification. For those skilled in the art, various modifications and changes can be made to the processes under the guidance of the present specification. However, these modifications and changes are still within the scope of the present specification.
[0163] Figure 7 is a schematic diagram of the effect evaluation model shown according to some embodiments of the present specification.
[0164] In some embodiments, when it is necessary to determine the current preservation effect of the current preservation plan, the control unit can enable the effect evaluation model to determine the current preservation effect of the current preservation plan.
[0165] As Figure 7 shown, the control unit can determine the current preservation effect 760 of the current preservation plan based on the initial liquid index 560, the current preservation plan 720, and the environmental data sequence 730 and status data sequence 740 corresponding to the current preservation plan, through the effect evaluation model 750.
[0166] The environmental data sequence 730 can be a sequence constructed based on the environmental data at multiple time points within the current time period. The multiple time points can refer to several time points during the operation period of the preservation plan within the current time period.
[0167] The status data sequence 740 can be a sequence constructed from status data at multiple time points within the current time period. The status data sequence 740 can include a visual data sequence and a pH data sequence.
[0168] For more information about environmental data and status data, please refer to Figure 6 and its related descriptions.
[0169] The effect evaluation model 750 can be applicable to determine the current preservation effect 760 of the current preservation plan. In some embodiments, the effect evaluation model 750 can be one or more of machine learning models such as a convolutional neural network model, a deep learning model, etc.
[0170] In some embodiments, the effect evaluation model 750 can include a second embedding layer 751 and an effect evaluation layer 753.
[0171] The second embedding layer 751 can be used to determine the visual feature sequence 752. The visual feature sequence 752 can reflect the visual features of the target liquid at multiple time points within the current time period. For example, the visual feature sequence 752 can be constructed from different visual features. For example, the visual feature sequence 752 can include features such as the color and transparency of the target liquid at multiple time points within the current time period. The second embedding layer 751 can be a convolutional neural network model.
[0172] In some embodiments, for the visual data of one time point in the visual data sequence 710, the input of the second embedding layer 751 can include the visual data, and the output can include the visual feature of this time point. The control unit can determine the visual feature sequence based on the visual features of each time point within the current time period. At this time, the second embedding layer 751 and the first embedding layer 541 can share parameters.
[0173] In some embodiments, as Figure 7 shown, the input of the second embedding layer 751 can also include the visual data sequence 710, and the output can be the corresponding visual feature sequence 752.
[0174] The effect evaluation layer 753 can be used to determine the preservation effect of the current preservation plan. The effect evaluation layer can be a deep learning model.
[0175] In some embodiments, as Figure 7 shown, the input of the effect evaluation layer 753 can include the visual feature sequence 752, the status data sequence 740, the environmental data sequence 730, the initial liquid index 560, and the current preservation plan 720, and the output can include the current preservation effect 760.
[0176] In some embodiments, the effect evaluation model can be obtained through joint training similar to that in Figure 6 based on a large number of second training samples with second labels. Each group of second training samples can include a sample status data sequence, a sample environment data sequence, a sample initial liquid index, and a sample current storage scheme. The second labels can include the sample current storage effects corresponding to the second training samples. The second training samples can include the historical visual feature sequence, historical status data sequence, historical environment data sequence, and historical initial liquid index corresponding to the historical current storage scheme in the historical data. The second labels can be obtained based on manual or automatic annotation. The second labels are determined based on the actual storage effects of the liquid in the historical data. For example, the second labels can be manually determined based on the actual liquid indexes of the target liquid of the sample after storage in the historical data (indexes accurately measured by instruments, etc.).
[0177] When the input of the second embedding layer 751 can include the visual data and the output can include the visual features at this time point, when training the effect evaluation model, the parameters of the first embedding layer in the trained index evaluation model can also be migrated to the second embedding layer as the parameters of the second embedding layer; the parameters of the second embedding layer are fixed, and the effect evaluation layer is trained.
[0178] In some embodiments, by migrating the parameters of the first embedding layer of the index evaluation model to the second embedding layer. When training the evaluation model, the control unit can fix the parameters of the second embedding layer and determine the initial visual feature sequence based on the processing of the sample visual data sequence by the second embedding layer. Then, the control unit can input the sample status data sequence, sample environment data sequence, sample initial liquid index, sample current storage scheme, and sample initial visual feature sequence into the initial effect evaluation layer to determine the output of the initial effect evaluation layer; a loss function is constructed based on the output of the initial effect evaluation layer and the second labels. The initial effect evaluation layer is updated based on the loss function, and the trained effect evaluation layer is determined through parameter update.
[0179] In some embodiments of this specification, by determining the storage effect of the current storage scheme through the effect evaluation model, the self-learning ability of the machine learning model can be utilized to improve the accuracy and efficiency of determining the storage effect of the current storage scheme. By migrating the parameters of the first embedding layer in the trained index evaluation model to the second embedding layer, it is beneficial to solve the problem of difficult label acquisition when training the second embedding layer alone, improve the training efficiency of the effect evaluation model, and reduce the training difficulty.
[0180] The basic concepts have been described above. Obviously, for those skilled in the art, the above detailed disclosure is only an example and does not constitute a limitation to this specification. Although not explicitly stated here, those skilled in the art may make various modifications, improvements, and corrections to this specification. Such modifications, improvements, and corrections are suggested in this specification, so such modifications, improvements, and corrections still fall within the spirit and scope of the exemplary embodiments of this specification.
[0181] At the same time, this specification uses specific terms to describe the embodiments of this specification. Such as "one embodiment", "an embodiment", and / or "some embodiments" mean a certain feature, structure, or characteristic related to at least one embodiment of this specification. Therefore, it should be emphasized and noted that the "one embodiment" or "an embodiment" or "an alternative embodiment" mentioned twice or more at different positions in this specification does not necessarily refer to the same embodiment. In addition, certain features, structures, or characteristics in one or more embodiments of this specification can be appropriately combined.
[0182] In addition, unless explicitly stated in the claims, the order of the processing elements and sequences, the use of numerical letters, or the use of other names in this specification are not used to limit the order of the processes and control systems of this specification. Although some currently considered useful embodiments of the invention are discussed through various examples in the above disclosure, it should be understood that such details only serve the purpose of illustration. The appended claims are not limited to the disclosed embodiments. On the contrary, the claims are intended to cover all modifications and equivalent combinations that conform to the essence and scope of the embodiments of this specification. For example, although the system components described above can be implemented by hardware devices, they can also be implemented only through software solutions, such as installing the described system on existing servers or mobile devices.
[0183] Similarly, it should be noted that, in order to simplify the expression of the disclosure of this specification and thus help the understanding of one or more embodiments of the invention, in the previous description of the embodiments of this specification, sometimes multiple features are merged into one embodiment, drawing, or description thereof. However, this disclosure method does not mean that the features required by the subject matter of this specification are more than those mentioned in the claims. In fact, the features of the embodiments are less than all the features of the individual embodiments disclosed above.
[0184] In some embodiments, numbers are used to describe components and the quantity of attributes. It should be understood that such numbers used in the description of embodiments are, in some examples, modified by the modifiers "about", "approximate" or "substantially". Unless otherwise specified, "about", "approximate" or "substantially" indicate that the said numbers allow a variation of ±20%. Accordingly, in some embodiments, the numerical parameters used in the specification and claims are approximate values, which may vary according to the characteristics required by individual embodiments. In some embodiments, the numerical parameters should consider the specified significant digits and adopt the method of retaining the general number of digits. Although the numerical ranges and parameters used in some embodiments of this specification to confirm the breadth of their scope are approximate values, in specific embodiments, such numerical settings are as precise as possible within the feasible range.
[0185] For each patent, patent application, patent application publication and other materials cited in this specification, such as articles, books, specifications, publications, documents, etc., their entire contents are hereby incorporated into this specification by reference. Except for the application history documents that are inconsistent with or conflict with the content of this specification, and except for the documents that limit the broadest scope of the claims of this specification (currently or subsequently attached to this specification). It should be noted that if there are inconsistencies or conflicts between the descriptions, definitions, and / or uses of terms in the supplementary materials of this specification and the content described in this specification, the descriptions, definitions, and / or uses of terms in this specification shall prevail.
[0186] Finally, it should be understood that the embodiments described in this specification are only used to illustrate the principles of the embodiments of this specification. Other variations may also fall within the scope of this specification. Therefore, by way of example and not limitation, alternative configurations of the embodiments of this specification may be considered to be consistent with the teachings of this specification. Accordingly, the embodiments of this specification are not limited to the embodiments explicitly introduced and described in this specification.
Claims
1. A storage device for multiple pathogen detection, characterized in that: The device comprises an outer box (110), a storage tube (120), a power support (140), a connecting hose (130), a preservative release unit (170), a temperature control unit (160), a control unit (180), a monitoring unit and an interaction unit, wherein: The storage tube (120) is configured to contain a target liquid that needs to be stored, and the storage tube (120) is detachably mounted on the tray (141) of the power support (140); The power support (140) is configured to drive the storage tube (120) to rotate; The preservative releasing unit (170) is configured to release the preservative required for preserving the target liquid, and the preservative releasing unit (170) is connected to the connecting hose (130); The connecting hose (130) is configured to transfer the preservative released by the preservative releasing unit (170) to the storage tube (120); The temperature control unit (160) is configured to adjust the temperature of the storage environment of the target liquid; The monitoring unit is configured to monitor monitoring data of a storage environment of the target liquid; The interaction unit is configured to allow a user to interact with the liquid storage device; The preservative release unit (170) and the temperature control unit (160) are arranged in the box body of the outer box (110); The control unit (180) is configured to: Determine a target storage scheme for storing the target liquid by the liquid storage device (580); generating target operating parameters of the liquid storage device based on the target storage scheme (580); Based on the target operating parameter, at least one of the preservative release unit (170), the temperature control unit (160) and the power support (140) is controlled to operate.
2. The storage device for multiple pathogen detection according to claim 1, characterized in that: An anti-backflow valve (150) is provided at one end of the connecting hose (130) close to the storage tube (120). The anti-backflow valve (150) is configured to prevent the target liquid from backflowing from the storage tube (120) to the connecting hose (130).
3. The storage device for multiple pathogen detection according to claim 1, characterized in that: The interaction unit is further configured to receive liquid information of the target liquid input by a user (530); The control unit (180) is further configured to: Based on the liquid information (530), the target storage plan (580) for storing the target liquid by the liquid storage device is determined.
4. The storage device for multiple pathogen detection according to claim 1, characterized in that: The monitoring data includes environmental data of the storage environment and state data of the target liquid, and the monitoring unit includes an environmental monitoring subunit and a state monitoring subunit; The environment monitoring subunit is configured to monitor environment data of the storage environment, wherein the environment data includes at least one of air pressure data, temperature data, and vibration data; The state monitoring subunit is configured to monitor state data of the target liquid, wherein the state data includes at least one of pH data and visual data; The control unit (180) is further configured to: Obtaining a current storage plan for storing the target liquid in the current time period of the liquid storage device (720); Based on the environment data, the state data and the current preservation scheme (720) in the current time period, the target preservation scheme (580) in the target time period is determined.
5. A control system for multiple pathogen detection, characterized in that: The control system (200) is used to control the operation of the storage device for serious pathogen detection according to any one of claims 1 to 4, comprising: A determination module (210) for determining a target storage scheme (580) for storing a target liquid by the liquid storage device; A generating module (220) for generating target operating parameters of the liquid storage device based on the target storage scheme (580); The control module (230) controls the operation of at least one of the preservative release unit (170), the temperature control unit (160) and the power support (140) based on the target operation parameter.
6. The control system for multiple pathogen detection according to claim 5, characterized in that: The determination module (210) is further configured to: receiving liquid information of the target liquid input by a user through an interaction unit (530); Based on the liquid information (530) of the target liquid, the target storage plan (580) for storing the target liquid by the liquid storage device is determined.
7. The control system for multiple pathogen detection according to claim 5, characterized in that: The determination module (210) is further configured to: Acquiring environmental data through the environmental monitoring subunit, wherein the environmental data includes at least one of air pressure data, temperature data, and vibration data; Acquiring state data through a state monitoring subunit, wherein the state data includes at least one of pH data and visual data; Obtaining a current storage plan for storing the target liquid in the current time period of the liquid storage device (720); Based on the environment data, the state data and the current preservation scheme (720) in the current time period, the target preservation scheme (580) in the target time period is determined.
8. A control method for detecting multiple pathogens, characterized in that: The control method is applied to the storage device for multiple pathogen detection according to any one of claims 1 to 4, and the control method comprises: Determine a target storage scheme for storing the target liquid by the liquid storage device (580); generating target operating parameters of the liquid storage device based on the target storage scheme (580); Based on the target operating parameter, at least one of the preservative release unit (170), the temperature control unit (160) and the power support (140) is controlled to operate.
9. The control method for multiple pathogen detection according to claim 8, wherein generating target operating parameters of the liquid storage device based on the target storage scheme (580) comprises: Acquiring environmental data through the environmental monitoring subunit, wherein the environmental data includes at least one of air pressure data, temperature data, and vibration data; Acquiring state data through a state monitoring subunit, wherein the state data includes at least one of pH data and visual data; Obtaining a current storage plan for storing the target liquid in the current time period of the liquid storage device (720); Based on the environment data, the state data and the current preservation scheme (720) in the current time period, the target preservation scheme (580) in the target time period is determined.