Automatic dyeing device for glass slide

Abstract

The invention belongs to the technical field of experimental equipment, and provides an automatic glass slide dyeing device which comprises a machine body, a dyeing jar, a heating assembly, a grabbing assembly, a timing assembly and a controller. The controller is electrically connected with the heating assembly, the grabbing assembly and the timing assembly. The three dyeing jars are respectively used for storing a trypsin solution, normal saline and dye liquor; the heating assemblies are used for heating the corresponding dyeing jars and keeping the dyeing jars at a preset temperature; the grabbing assembly is used for grabbing a target glass slide and transferring the target glass slide to a target position; the timing assembly is used for recording time information of the grabbing assembly for placing the target glass slide at the target position and transmitting the time information to the controller, and the controller converts the received information into a corresponding electric signal so as to control the operation state of the grabbing assembly. The glass slide automatic dyeing device provided by the invention is simple in structure, can automatically dye the target glass slide, and is convenient to operate.

Description

Technical Field

[0001] The present invention relates to the technical field of experimental equipment, and particularly relates to an automatic slide staining device. Background Art

[0002] In the process of performing chromosome karyotype analysis experiments, when staff members stain slides carrying chromosomes, the following steps are required:

[0003] S1, Place the slide carrying chromosomes in a trypsin cylinder for 33 seconds;

[0004] S2, Rinse the slide processed in step S1 in a physiological saline cylinder;

[0005] S3, Place the slide processed in step S2 in a staining solution cylinder for 4 minutes;

[0006] S4, Rinse the slide processed in step S3 with water;

[0007] S5, Dry the slide processed in step S4 with a blower;

[0008] S6, Place the slide processed in step S5 under a microscope for inspection to judge the banding effect.

[0009] However, in the prior art, staff members usually need to manually operate all steps, which is not only cumbersome but also takes a relatively long overall working time, greatly increasing the labor intensity of the staff. Summary of the Invention

[0010] Aiming at the defects in the prior art, the purpose of the present invention is to provide an automatic slide staining device to automatically perform staining operations on slides, thereby solving the above-mentioned technical problems existing in the prior art.

[0011] To achieve the above purpose, the present invention provides an automatic slide staining device, including a machine body and a staining cylinder, a heating component, a grasping component, a timing component and a controller arranged on the machine body;

[0012] Wherein, the controller is electrically connected to the heating component, the grasping component and the timing component;

[0013] There are three staining cylinders, and the three staining cylinders are arranged on the machine body. The three staining cylinders are respectively used for storing trypsin solution, physiological saline and staining solution;

[0014] The heating component is used to heat the three staining cylinders and keep the three staining cylinders at a preset temperature;

[0015] The grasping component is used to grasp the target glass slide and transfer the target glass slide to the target position;

[0016] The timing component is used to record the time information when the grasping component places the target glass slide at the target position and transmit the time information to the controller, and the controller converts the received information into corresponding electrical signals to control the operating state of the grasping component.

[0017] Further, it further includes:

[0018] A rinsing component, which is arranged on the machine body, is electrically connected to the control, and is used to rinse the target glass slide; and

[0019] A drying component, which is arranged on the machine body, is electrically connected to the control, and is used to dry the target glass slide.

[0020] Further, the heating component includes:

[0021] Three water baths, which are arranged on the machine body, and the staining cylinders are correspondingly arranged in the water baths;

[0022] Temperature sensors, which are in one-to-one correspondence with the water baths, are arranged in the corresponding water baths, and the temperature sensors are electrically connected to the controller;

[0023] Electric heating elements, which are in one-to-one correspondence with the water baths, are arranged in the corresponding water baths, and the electric heating elements are electrically connected to the controller;

[0024] Wherein, the electric heating element is used to heat the liquid medium in the water bath, the temperature sensor is used to detect the temperature information of the liquid medium in the water bath and transmit the temperature information to the controller, and the controller is used to convert the received electrical signal into a corresponding control signal to control the operating state of the electric heating element.

[0025] Further, the water bath includes:

[0026] A pot body, which is arranged on the machine body; and

[0027] A support mechanism, which is arranged in the pot body, and the support mechanism is used to support the staining cylinder so that the staining cylinder floats in the water bath.

[0028] Further, the support mechanism includes:

[0029] A support ring, which is connected to the inner side wall of the pot body;

[0030] A support element, which is inclined, and the top end of the support element is closer to the axis line of the support ring. The support element is hinged to the support ring. There are multiple support elements, and the multiple support elements are arranged at intervals in sequence around the axis line of the support ring; and

[0031] A first elastic element, which is arranged on the support ring. In the natural state, the first elastic element applies an elastic force to the support element so that the top end of the support element has a tendency to move in a direction close to the axis line of the support ring.

[0032] Further, the support mechanism further includes:

[0033] A guide ring, which is coaxially arranged with the support ring and fixedly connected to the support ring; and

[0034] A guide element, the bottom end of which is hinged to the top end of the support element, the upper end of the guide element is movably connected to the guide ring, the guide element is inclined, and the distance between the bottom end of the guide element and the axis line of the guide ring is relatively close. When placing the dyeing cylinder, the dyeing cylinder can apply a force to the support element through the guide element to drive the top end of the support element to move in a direction away from the axis line of the support ring.

[0035] Further, the grasping assembly includes:

[0036] A sliding seat, which is slidably connected to the machine body, and the sliding seat can make a reciprocating linear motion between a first position and a second position along the transverse direction;

[0037] A first driving mechanism, which is arranged on the machine body. The first driving mechanism is used to drive the sliding seat to make a reciprocating linear motion between the first position and the second position and can hold the sliding seat at the target position;

[0038] A lifting seat, which is arranged below the sliding seat, and the lifting seat is slidably connected to the sliding seat so that the lifting seat can make a lifting motion along the longitudinal direction;

[0039] A second driving mechanism, which is arranged on the sliding seat. The second driving mechanism is used to drive the lifting seat to make a lifting motion and can hold the lifting seat at the target position;

[0040] A rotating seat, which is arranged at the bottom of the lifting seat and is rotatably connected to the lifting seat;

[0041] A third driving mechanism, which is arranged on the lifting seat. The third driving mechanism is used to drive the rotating seat to rotate and can hold the rotating seat at the target position;

[0042] A swing seat is arranged at the bottom of the rotating seat, and the top of the swing seat is hinged to the bottom of the rotating seat;

[0043] A fourth driving mechanism is arranged on the rotating seat. The fourth driving mechanism is used to drive the swing seat to swing reciprocally within a preset angle β and can keep the swing seat at a target position;

[0044] A grasping mechanism is arranged at the bottom of the swing seat. The grasping mechanism has mutually switchable grasping states and releasing states.

[0045] Furthermore, the grasping mechanism includes:

[0046] Two grasping arms are arranged. The two grasping arms are symmetrically arranged at the bottom of the swing seat. The grasping arms are slidably connected to the swing seat so that the two grasping arms can approach or separate from each other; and

[0047] A driving structure is arranged on the swing seat. The driving structure is used to drive the two grasping arms to approach or separate from each other.

[0048] Furthermore, the driving structure includes:

[0049] A slider is slidably arranged in the swing seat. The slider can move along a direction approaching or separating from the grasping arm;

[0050] A first permanent magnet is fixedly embedded in the slider;

[0051] A first electromagnet is fixedly arranged in the swing seat, and the magnetic property of the side of the first electromagnet opposite to the first permanent magnet is different;

[0052] Stay ropes are in one-to-one correspondence with the grasping arms. The first end of each stay rope is connected to the corresponding grasping arm, and the second end is connected to the slider; and

[0053] A second elastic element has two ends respectively connected to the two grasping arms. In a natural state, the second elastic element applies an elastic force to the two grasping arms so that the two grasping arms tend to separate from each other.

[0054] Furthermore, the stay rope is made of an elastic material;

[0055] The grasping mechanism further includes a winding structure arranged on the slider. The winding structure is used to wind or release the stay rope to change the extended length of the stay rope.

[0056] Advantages of the present invention:

[0057] The automatic slide staining device provided by the present invention has a simple structure and a reasonable design. It can automatically stain slides, is convenient to operate, and reduces the labor intensity of workers. BRIEF DESCRIPTION OF THE DRAWINGS

[0058] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for the description of the specific embodiments or the prior art. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts are not necessarily drawn to scale.

[0059] Figure 1 A three-dimensional view of the automatic slide staining device provided by Embodiment 1 of the present invention;

[0060] Figure 2 A three-dimensional view of the automatic slide staining device provided by Embodiment 2 of the present invention;

[0061] Figure 3 For Figure 1 and Figure 2 A three-dimensional view of the grasping assembly of the automatic slide staining device shown;

[0062] Figure 4 For Figure 3 An enlarged view of part A shown;

[0063] Figure 5 For Figure 3 An exploded three-dimensional view of the grasping mechanism and the swing seat of the grasping assembly shown;

[0064] Figure 6 For Figure 5 An enlarged view of part B shown;

[0065] Figure 7 For Figure 3 A cross-sectional view of the grasping assembly shown;

[0066] Figure 8 For Figure 7 An enlarged view of part C shown;

[0067] Figure 9 For Figure 7 An enlarged view of part D shown;

[0068] Figure 10 For Figure 1 and Figure 2 A combined three-dimensional view of the heating assembly and the staining cylinder of the automatic slide staining device shown;

[0069] Figure 11 For Figure 10 The cross-sectional view shown;

[0070] Figure 12 The Figure 11 magnified view of part E shown in the figure;

[0071] Figure 13 The Figure 11 exploded perspective view of the heating assembly and the dyeing cylinder shown in the figure;

[0072] Figure 14 The Figure 13 magnified view of part F shown in the figure;

[0073] Figure 15 The Figure 10 perspective view of the support mechanism of the heating assembly shown in the figure;

[0074] Figure 16 The Figure 2 perspective view of the rinsing assembly of the automatic slide staining device shown in the figure;

[0075] Figure 17 The Figure 2 perspective view of the air-drying assembly of the automatic slide staining device shown in the figure.

[0076] Reference numerals:

[0077] 100, body; 200, dyeing cylinder; 310, water bath; 311, pot body; 312, support ring; 313, support element; 314, first elastic element; 315, support rod; 316, support portion; 317, limit groove; 318, guide ring; 319, guide element; 320, temperature sensor; 330, electric heating element; 341, stirring rotor; 342, fifth motor; 343, second permanent magnet; 411, sliding seat; 412, lifting seat; 413, rotating seat; 414, swinging seat; 421, first lead screw; 422, first nut; 423, first motor; 431, electric push rod; 441, third motor; 451, fourth motor; 461, grasping arm; 462, slider; 463, first permanent magnet; 464, first electromagnet; 465, pull rope; 466, second elastic element; 471, rotating shaft; 472, winding drum; 473, knob; 474, fixed limit wheel; 475, moving limit wheel; 476, third elastic element; 477, operating handle; 510, rinsing head; 520, water pipe; 530, first control valve; 540, water pump; 610, air blowing head; 620, filtering device; 630, air pipe; 640, second control valve; 650, air pump. Detailed implementation manners

[0078] The embodiments of the technical solution of the present invention will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to illustrate the technical solution of the present invention more clearly, and therefore are only examples and cannot be used to limit the protection scope of the present invention.

[0079] It should be noted that unless otherwise specified, the technical terms or scientific terms used in this application should have the ordinary meanings understood by those skilled in the art to which the present invention belongs.

[0080] In the description of this application, it should be understood that the orientation or positional relationships indicated by the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. are based on the orientation or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present invention.

[0081] In addition, the terms "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. In the description of the present invention, "a plurality" means two or more unless otherwise specifically defined.

[0082] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed", etc. should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or integrated; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements or the interaction relationship between two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0083] In this application, unless otherwise clearly specified and limited, the first feature being "on" or "under" the second feature can be that the first and second features are in direct contact, or the first and second features are indirectly in contact through an intermediate medium. Moreover, the first feature being "above", "over" and "on" the second feature can be that the first feature is directly above or obliquely above the second feature, or merely indicates that the first feature has a higher horizontal height than the second feature. The first feature being "under", "beneath" and "under" the second feature can be that the first feature is directly below or obliquely below the second feature, or merely indicates that the first feature has a lower horizontal height than the second feature.

[0084] Such as Figure 1As shown in the figure, the present invention provides an automatic slide staining device, which includes a body 100 and a staining cylinder 200, a heating component, a grasping component, a timing component and a controller arranged on the body 100.

[0085] Among them, the controller is electrically connected to the heating component, the grasping component and the timing component.

[0086] There are three staining cylinders 200, which are arranged on the body 100. The three staining cylinders 200 are respectively used to store trypsin solution, physiological saline and staining solution. For the convenience of explaining the working principle of the automatic slide staining device, here we name the three staining cylinders 200 as staining cylinder A, staining cylinder B and staining cylinder C respectively. Among them, staining cylinder A is used to store trypsin solution, where the trypsin solution consists of 50 ml of PBS + 0.2 g of trypsin, staining cylinder B is used to store physiological saline, and staining cylinder C is used to store staining solution.

[0087] The heating component is used to heat the three staining cylinders 200 and keep the three staining cylinders 200 at a preset temperature. Specifically, in this embodiment, the preset temperature is 37°C. The grasping component is used to grasp the target slide and transfer the target slide to the target position. Specifically, the target position includes inside the three staining cylinders 200, at the water outlet of the rinsing component and at the air outlet of the air drying component.

[0088] The timing component is used to record the time information when the grasping component places the target slide at the target position and transmit the time information to the controller. The controller converts the received information into corresponding electrical signals to control the running state of the grasping component. Specifically, the timing component includes a timer. The timer is electrically connected to the controller.

[0089] Specifically, S1, the controller controls the grasping component to place the target slide in staining cylinder A for a preset time. In this embodiment, the preset time is 33 seconds;

[0090] S2, the controller controls the grasping component to place the slide processed in step S1 in staining cylinder B for rinsing;

[0091] S3, the controller controls the grasping component to place the slide processed in step S2 in staining cylinder C for a preset time. In this embodiment, the preset time is 4 minutes.

[0092] During this process, when the timing component records that the time when the grasping component places the target slide in staining cylinder A reaches the preset time (33 seconds), the timing component transmits the information to the controller, and the controller controls the grasping component to transfer the slide to staining cylinder B for brushing.

[0093] After rinsing is completed, the controller controls the grasping component to transfer the glass slide into the staining tank C. When the timing component records that the time for the glass slide placed in the staining tank C reaches the preset time (4 minutes), the timing component transmits the information to the controller, and the controller controls the grasping component to remove the glass slide from the staining tank C.

[0094] It has a simple structure and reasonable design, can automatically stain glass slides, is convenient to operate, and reduces the labor intensity of staff.

[0095] As Figure 2 shown, in this embodiment, the automatic glass slide staining device further includes a rinsing component and a drying component.

[0096] The rinsing component and the drying component are arranged on the machine body 100, and the rinsing component and the drying component are electrically connected to the controller. The rinsing component is used to rinse the target glass slide. The drying component is used to dry the target glass slide.

[0097] Specifically, in S4, the controller controls the grasping component to transfer the glass slide processed in step S3 to the rinsing component. After that, the controller controls the rinsing component to start to rinse the glass slide;

[0098] In S5, the controller controls the grasping component to transfer the glass slide processed in step S4 to the drying component. After that, the controller controls the drying component to start to dry the glass slide.

[0099] In this embodiment, by setting the rinsing component and the drying component, the manual operation steps of the staff are further reduced, and the labor intensity of the staff is further reduced.

[0100] As Figure 11 、 13 shown, in this embodiment, the heating component includes a water bath 310, a temperature sensor 320, and an electric heating element 330.

[0101] There are three water baths 310, and the three water baths 310 are arranged on the machine body 100, and the staining tanks 200 are correspondingly arranged in the water baths 310. The temperature sensors 320 are in one-to-one correspondence with the water baths 310, the temperature sensors 320 are arranged in the corresponding water baths 310, and the temperature sensors 320 are electrically connected to the controller. The electric heating elements 330 are in one-to-one correspondence with the water baths 310, the electric heating elements 330 are arranged in the corresponding water baths 310, and the electric heating elements 330 are electrically connected to the controller.

[0102] Among them, the electric heating element 330 is used to heat the liquid medium in the water bath 310, the temperature sensor 320 is used to detect the temperature information of the liquid medium in the water bath 310 and transmit the temperature information to the controller, and the controller is used to convert the received electrical signal into a corresponding control signal to control the operating state of the electric heating element 330.

[0103] Specifically, when in use, a liquid medium (such as water) is loaded into the water bath 310, and the electric heating element 330 is used to heat the liquid medium in the water bath 310. During this process, when the temperature sensor 320 detects that the temperature of the liquid medium in the water bath 310 reaches the preset temperature, the temperature sensor 320 transmits the detected information to the controller, and the controller then controls the electric heating element 330 to reduce the heating power; when the temperature sensor 320 detects that the temperature of the liquid medium in the water bath 310 is lower than the preset temperature, the temperature sensor 320 transmits the detected information to the controller, and the controller then controls the electric heating element 330 to increase the heating power, so as to achieve the purpose of maintaining the temperature of the liquid medium in the water bath 310 at the preset temperature.

[0104] As Figure 11 、 13 shown, in this embodiment, the heating assembly further includes a magnetic stirrer, and the magnetic stirrer includes a stirring rotor 341 disposed in the water bath 310 and a fifth driving structure disposed on the body 100 and used to drive the stirring rotor 341 to rotate. The fifth driving structure includes a fifth motor 342 and a second permanent magnet 343 disposed on the power output shaft of the fifth motor 342.

[0105] In this embodiment, by providing the magnetic stirrer, the liquid medium in the water bath 310 is heated more uniformly, and during the stirring process, the liquid in the water bath 310 will also be more stable.

[0106] As Figure 10 、 11 、12, 13, 14, 15 shown, in this embodiment, the water bath 310 includes a pot body 311 and a support mechanism.

[0107] The pot body 311 is disposed on the body 100. The support mechanism is disposed in the pot body 311, and the support mechanism is used to support the dyeing cylinder 200 so that the dyeing cylinder 200 floats in the water bath 310.

[0108] As Figure 10 、 11 、12, 13, 14, 15 shown, in this embodiment, the support mechanism includes a support ring 312, a support element 313, and a first elastic element 314.

[0109] Among them, the support ring 312 is connected to the inner side wall of the pot body 311. The support element 313 is inclined, and the top end of the support element 313 is closer to the axis line of the support ring 312. The support element 313 is hinged to the support ring 312. There are multiple support elements 313, and the multiple support elements 313 are arranged at intervals in sequence around the axis line of the support ring 312. Preferably, the multiple support elements 313 are evenly arranged around the axis line of the support ring 312.

[0110] The first elastic element 314 is arranged on the support ring 312. In the natural state, the first elastic element 314 exerts an elastic force on the support element 313, so that the top end of the support element 313 has a tendency to move in the direction close to the axis line of the support ring 312. Among them, the first elastic element 314 can be any first elastic element 314 that can exert an elastic force on the support element 313, such as: torsion spring, volute torsion spring, annular spring, annular rubber band, etc.

[0111] Among them, when the first elastic element 314 is a torsion spring or a volute torsion spring, the first elastic element 314 corresponds to the support element 313 one by one. The first elastic element 314 is arranged at the hinge center of the corresponding support element 313. The two ends of the first elastic element 314 are respectively connected to the support ring 312 and the support element 313. In the natural state, the first elastic element 314 exerts an elastic force on the support element 313, so that the top end of the support element 313 has a tendency to move in the direction close to the axis line of the support ring 312.

[0112] Among them, when the first elastic element 314 is an annular spring or an annular rubber band, the first elastic element 314 is sleeved on all the support elements 313. In the natural state, the first elastic element 314 exerts an elastic force on the support element 313, so that the top end of the support element 313 has a tendency to move in the direction close to the axis line of the support ring 312. As Figure 11 、 12 、15 shown, in this embodiment, the first elastic element 314 is an annular spring.

[0113] When placing the dyeing cylinder 200 in the water bath 310, insert the dyeing cylinder 200 into the support ring 312. Under the action of the elastic force of the first elastic element 314, the top end of the support element 313 abuts against the outer side wall of the dyeing cylinder 200. During this process, the dyeing cylinder 200 always has a tendency to move downward under the action of gravity. And the top end of the support element 313 has a tendency to move in the direction of the axis line of the support ring 312 under the action of the friction force between it and the dyeing cylinder 200, so as to squeeze the dyeing cylinder 200 to increase the friction force between the dyeing cylinder 200 and the support element 313, and further achieve the purpose of supporting the dyeing cylinder 200.

[0114] When removing the dyeing cylinder 200, an upward acting force is applied to the dyeing cylinder 200. Under the action of the frictional force between the dyeing cylinder 200 and the support element 313, the top end of the support element 313 moves away from the axis line of the support ring 312 against the elastic force of the first elastic element 314, so as to achieve the purpose of facilitating the removal of the dyeing cylinder 200.

[0115] As Figure 10 , 11 , 12, 13, 14, 15 show that in this embodiment, the support mechanism further includes a support rod 315. The first end of the support rod 315 is fixedly connected to the outer side wall of the support ring 312, and the second end is connected to the pot body 311. A plurality of support rods 315 are provided, and the plurality of support rods 315 are arranged at intervals in sequence around the axis line of the support ring 312. Preferably, the plurality of support rings 312 are evenly arranged around the axis line of the support rod 315.

[0116] A support portion 316 is fixedly provided on the inner side wall of the pot body 311. It should be noted that the support portion 316 can be provided separately or integrally formed with the pot body 311. A limit groove 317 adapted to the support rod 315 is provided at the top of the support portion 316. In the working state, the second end of the support rod 315 is placed in the limit groove 317. In the non-working state, the support rod 315 is taken out from the limit groove 317, so as to take out the support mechanism from the pot body 311, which is convenient for cleaning.

[0117] As Figure 10 , 11 , 12, 13, 14, 15 show that in this embodiment, the support mechanism further includes a guide ring 318 and a guide element 319.

[0118] The guide ring 318 is coaxially arranged with the support ring 312 and fixedly connected to the support ring 312. The guide element 319 is inclined, and the distance between the bottom end of the guide element 319 and the axis line of the guide ring 318 is relatively close. The bottom end of the guide element 319 is hinged to the top end of the support element 313, and the upper end of the guide element 319 is movably connected to the guide ring 318. When placing the dyeing cylinder 200, the dyeing cylinder 200 can apply a force to the support element 313 through the guide element 319 to drive the top end of the support element 313 to move away from the axis line of the support ring 312, so as to achieve the purpose of facilitating the placement of the dyeing cylinder 200.

[0119] As Figure 11 , 12 As shown, an annular groove adapted to the support rod 315 is coaxially provided on the outer side wall of the dyeing cylinder 200. During use, the top end of the support rod 315 is embedded in the annular groove, so as to achieve the purpose of improving the support effect. At the same time, through the cooperation of the annular groove and the support rod 315, the dyeing cylinder 200 can also be positioned to ensure that the dyeing cylinder 200 is placed in place.

[0120] As Figure 1-9 shown, the grasping assembly includes a sliding seat 411, a first driving mechanism, a lifting seat 412, a second driving mechanism, a rotating seat 413, a third driving mechanism, a swinging seat 414, a fourth driving mechanism and a grasping mechanism.

[0121] The sliding seat 411 is slidably connected to the body 100, and the sliding seat 411 can reciprocate linearly between a first position and a second position in the lateral direction. The first driving mechanism is disposed on the body 100, and the first driving mechanism is configured to drive the sliding seat 411 to reciprocate linearly between the first position and the second position and to be able to hold the sliding seat 411 at a target position. Specifically, the target positions include positions corresponding to the dyeing vats A, B, C, the rinsing assembly and the air drying assembly.

[0122] The lifting seat 412 is disposed below the sliding seat 411, and the lifting seat 412 is slidably connected to the sliding seat 411 so that the lifting seat 412 can move up and down in the longitudinal direction. The second driving mechanism is disposed on the sliding seat 411, and the second driving mechanism is configured to drive the lifting seat 412 to move up and down and to be able to hold the lifting seat 412 at a target position. Specifically, the target positions include the positions corresponding to the lifting seat when the slide is in the dyeing vat and when the slide is above the dyeing vat.

[0123] The rotating seat 413 is disposed at the bottom of the lifting seat 412 and is rotatably connected to the lifting seat 412. The third driving mechanism is disposed on the lifting seat 412, and the third driving mechanism is configured to drive the rotating seat 413 to rotate and to be able to hold the rotating seat 413 at a target position. Specifically, the target positions include the positions corresponding to the rotating seat 413 when the A side of the slide faces the rinsing assembly or the air drying assembly and when the B side (the side opposite to the A side) of the slide faces the rinsing assembly or the air drying assembly.

[0124] Preferably, the third driving mechanism is configured to drive the rotating seat 413 to reciprocally swing within a preset angle α range, where α is from -180° to +180°, that is, the third driving mechanism can drive the rotating seat 413 to rotate 180° in the positive and negative directions from the initial position.

[0125] The swing seat 414 is arranged at the bottom of the rotating seat 413, and the top of the swing seat 414 is hinged to the bottom of the rotating seat 413. The fourth driving mechanism is arranged on the rotating seat 413 and is used to drive the swing seat 414 to swing reciprocally within a preset angle β and can keep the swing seat 414 at the target position. Specifically, the target positions include the corresponding positions of the swing seat 414 when the A side of the slide faces the water outlet of the flushing component or the air outlet of the air drying component and when the B side of the slide faces the water outlet of the flushing component or the air outlet of the air drying component. Among them, β is from -90° to +90°, that is, the third driving mechanism can drive the swing seat 414 to rotate 90° in the positive and negative directions from the initial position.

[0126] The grasping mechanism is arranged at the bottom of the swing seat 414 and has mutually switchable grasping and releasing states. The grasping component switches from the releasing state to the grasping state to grasp the slide, and switches from the grasping state to the releasing state to release the slide.

[0127] In use, the grasping component is switched from the releasing state to the grasping state so that the grasping mechanism grabs the target slide. Then, the first driving mechanism drives the sliding seat 411 to move to move the grasping mechanism above the staining tank A; then, the second driving mechanism drives the lifting seat 412 to descend to place the slide in the staining tank A.

[0128] When the time of the slide in the staining tank A reaches the preset time, the second driving mechanism drives the lifting seat 412 to rise to remove the slide from the staining tank A; then, the first driving mechanism drives the sliding seat 411 to move to move the grasping component above the staining tank B, and then, the second driving mechanism drives the lifting seat 412 to descend to place the slide in the staining tank B; then, the second driving mechanism drives the lifting seat 412 to reciprocally lift and lower within a preset range, so that the slide moves up and down in the staining tank B to wash the slide.

[0129] When the washing is completed, the second driving mechanism drives the lifting seat 412 to rise to remove the slide from the staining tank B; then, the first driving mechanism drives the sliding seat 411 to move to move the grasping component above the staining tank C, and then, the second driving mechanism drives the lifting seat 412 to descend to place the slide in the staining tank C.

[0130] When the time of the slide in the staining tank C reaches the preset time, the second driving mechanism drives the lifting seat 412 to rise to move the slide out of the staining tank C; then, the first driving mechanism drives the sliding seat 411 to move to transfer the slide to the rinsing assembly to rinse the slide. Specifically, the third driving mechanism drives the rotating seat 413 to rotate, and the fourth driving mechanism drives the swinging seat 414 to rotate so that the A side of the slide faces the rinsing assembly to enable the rinsing assembly to rinse the A side of the slide; then, the third driving mechanism drives the rotating seat 413 to rotate, and the fourth driving mechanism drives the swinging seat 414 to rotate so that the B side of the slide faces the rinsing assembly to enable the rinsing assembly to rinse the B side of the slide.

[0131] After rinsing is completed, the first driving mechanism drives the sliding seat 411 to move to transfer the slide to the air-drying assembly to air-dry the slide. Specifically, the third driving mechanism drives the rotating seat 413 to rotate, and the fourth driving mechanism drives the swinging seat 414 to rotate so that the A side of the slide faces the air-drying assembly to enable the air-drying assembly to dry the A side of the slide; then, the third driving mechanism drives the rotating seat 413 to rotate, and the fourth driving mechanism drives the swinging seat 414 to rotate so that the B side of the slide faces the air-drying assembly to enable the air-drying assembly to dry the B side of the slide.

[0132] As Figure 3 shown, the first driving mechanism includes a first lead screw 421, a first nut 422, and a first motor 423.

[0133] Among them, the axis line of the first lead screw 421 is arranged horizontally, and the first lead screw 421 is rotatably connected to the machine body 100. The first nut 422 is sleeved on the first lead screw 421, and the first nut 422 is in transmission connection with the first lead screw 421 so that when the first lead screw 421 rotates, it can drive the first nut 422 to move along the axis line of the first lead screw 421. The first motor 423 is fixedly installed on the machine body 100, and the power output shaft of the first motor 423 is in transmission connection with the power input end of the first lead screw 421 to drive the first lead screw 421 to rotate.

[0134] Specifically, when the first motor 423 drives the first lead screw 421 to rotate in the forward direction, the sliding seat 411 is driven by the first nut 422 to move from the first position to the second position; when the first motor 423 drives the first lead screw 421 to rotate in the reverse direction, the sliding seat 411 is driven by the first nut 422 to move from the second position to the first position.

[0135] As Figure 3 、 4 、7 shows, the second driving mechanism includes an electric push rod 431.

[0136] The electric push rod 431 is fixedly connected to the sliding seat 411. The power output shaft of the electric push rod 431 is fixedly connected to the lifting seat 412. Specifically, when the electric push rod 431 extends, the electric push rod 431 drives the lifting seat 412 to descend; when the electric push rod 431 contracts, the electric push rod 431 drives the lifting seat 412 to ascend.

[0137] As Figure 3 , 4 , Figures 7 and 8 show that the third driving mechanism includes a third motor 441.

[0138] The third motor 441 is fixedly arranged on the lifting seat 412, and the power output shaft of the third motor 441 is in transmission connection with the power input shaft of the rotating seat 413. Specifically, the power input shaft of the rotating seat 413 is provided with a connection jack adapted to the power output shaft of the third motor 441. The connection jack is star-shaped, polygonal or elliptical, etc., and the power output shaft of the third motor 441 is inserted into the connection jack.

[0139] As Figure 3 , 4 , Figures 7 and 8 show that the fourth driving mechanism includes a fourth motor 451.

[0140] The fourth motor 451 is fixedly arranged on the rotating seat 413, and the power output shaft of the fourth motor 451 is in transmission connection with the power input shaft of the swinging seat 414. Specifically, a first bevel gear is coaxially sleeved on the power input shaft of the swinging seat 414, and a second bevel gear meshing with the first bevel gear is sleeved on the power output shaft of the fourth motor 451.

[0141] As Figure 5 , 6 , Figures 7 and 9 show that the grasping mechanism includes a grasping arm 461 and a driving structure.

[0142] There are two grasping arms 461, and the two grasping arms 461 are symmetrically arranged at the bottom of the swinging seat 414. The grasping arms 461 are slidably connected to the swinging seat 414 so that the two grasping arms 461 can approach or separate from each other. The driving structure is arranged on the swinging seat 414 and is used to drive the two grasping arms 461 to approach or separate from each other. Specifically, the driving structure drives the two grasping arms 461 to approach each other so that the grasping structure switches from the release state to the grasping state; the driving structure drives the two grasping arms 461 to separate from each other so that the grasping structure switches from the grasping state to the release state.

[0143] As Figure 5 , 6 , Figures 7 and 9 show that the driving structure includes a slider 462, a first permanent magnet 463, a first electromagnet 464, a pull rope 465 and a second elastic element 466.

[0144] The slider 462 is slidably arranged within the swing seat 414, and the slider 462 can move in a direction approaching or departing from the grasping arm 461. The first permanent magnet 463 is fixedly embedded within the slider 462. The first electromagnet 464 is fixedly arranged within the swing seat 414. The magnetic poles of the side of the first electromagnet 464 opposite to the first permanent magnet 463 are different, such that when the first electromagnet 464 is energized, a magnetic attraction force is generated between the first electromagnet 464 and the first permanent magnet 463.

[0145] The draw ropes 465 correspond one-to-one with the grasping arms 461. The first end of the draw rope 465 is connected to the grasping arm 461, and the second end is connected to the slider 462. Both ends of the second elastic element 466 are respectively connected to the two grasping arms 461, and in the natural state, the second elastic element 466 applies an elastic force to the two grasping arms 461, such that the two grasping arms 461 have a tendency to move away from each other. Specifically, the second elastic element 466 is any elastic element capable of applying an elastic force to the grasping arm 461, for example: a spring, a rubber spring, a pneumatic spring, a hydraulic spring, etc. In this embodiment, the second elastic element 466 is a spring.

[0146] When grasping, the first electromagnet 464 is energized. Since the magnetic poles of the side of the first electromagnet 464 opposite to the first permanent magnet 463 are different, therefore, a magnetic attraction force is generated between the first electromagnet 464 and the first permanent magnet 463. Under the action of this magnetic attraction force, the slider 462 is driven to move in a direction away from the grasping arm 461, and the slider 462 drives the two grasping arms 461 to approach each other through the draw rope 465 to grasp the glass slide.

[0147] When releasing, the first electromagnet 464 is powered off. Under the action of the elastic force of the second elastic element 466, the two grasping arms 461 move away from each other, thereby releasing the glass slide.

[0148] As shown in Figure 5 、 6 、7, and 9, the draw rope 465 is made of an elastic material. For example: rubber.

[0149] The grasping mechanism further includes a winding structure. The winding structure is arranged on the slider 462. The winding structure is used to wind or release the draw rope 465 to change the extended length of the draw rope 465, thereby changing the clamping force of the two grasping arms 461, and further achieving the purpose of preventing damage to the glass slide due to excessive clamping force. Specifically, when the extended length of the draw rope 465 increases, the deformation amount of the draw rope 465 when pulling the grasping arm 461 becomes smaller, the elastic force applied by the draw rope 465 to the grasping arm 461 becomes smaller, thereby making the grasping force smaller; when the extended length of the draw rope 465 becomes smaller, the deformation amount of the draw rope 465 when pulling the grasping arm 461 becomes larger, the elastic force applied by the draw rope 465 to the grasping arm 461 becomes larger, thereby making the grasping force larger.

[0150] As shown Figure 5 、 6 、7, and 9, the rewinding structure includes a rotating shaft 471, a winding drum 472, a knob 473, a fixed limiting wheel 474, a movable limiting wheel 475, a third elastic element 476, and an operating handle 477.

[0151] Among them, the rotating shaft 471 is arranged on the slider 462 and is rotatably connected to the slider 462. The winding drums 472 correspond one-to-one with the pulling ropes 465. The winding drums 472 are coaxially sleeved on the rotating shaft 471, and the winding drums 472 are drivingly connected to the rotating shaft 471 so that the rotating shaft 471 can drive the winding drums 472 to rotate. The first end of the pulling rope 465 is connected to the grasping arm 461, and the second end is connected to the winding drum 472. The knob 473 is coaxially sleeved on the first end of the rotating shaft 471, and the knob 473 is drivingly connected to the rotating shaft 471 so that the knob 473 can drive the rotating shaft 471 to rotate. Specifically, when the knob 473 drives the rotating shaft 471 to rotate in the first direction, the winding drum 472 winds the pulling rope 465; when the knob 473 drives the rotating shaft 471 to rotate in the second direction, the winding drum 472 releases the pulling rope 465. Among them, the first direction and the second direction are opposite.

[0152] The fixed limiting wheel 474 is coaxially sleeved on the second end of the rotating shaft 471, and the fixed limiting wheel 474 is fixedly connected to the rotating shaft 471. The movable limiting wheel 475 is arranged opposite to the fixed limiting wheel 474. The movable limiting wheel 475 is arranged inside the slider 462, and the movable limiting wheel 475 is slidably connected to the slider 462 so that the movable limiting wheel 475 can move in a direction close to or away from the fixed limiting wheel 474. And one side of the movable limiting wheel 475 opposite to the fixed limiting wheel 474 is provided with mutually matching one-way limiting teeth. In the working state, the movable limiting wheel 475 meshes with the fixed limiting wheel 474 so that the rotating shaft 471 can only rotate in the first direction. Among them, the first direction and the second direction are opposite.

[0153] The first end of the third elastic element 476 is connected to the slider 462, and the second end is connected to the movable limiting wheel 475. And in the natural state, the third elastic element 476 exerts an elastic force on the movable limiting wheel 475 so that the movable limiting wheel 475 has a tendency to move in a direction close to the fixed limiting wheel 474. The first end of the operating handle 477 is fixedly connected to the movable limiting wheel 475, and the second end extends outside the swing arm. Specifically, the third elastic element 476 is any elastic element that can exert an elastic force on the grasping arm 461, such as: a spring, a rubber spring, a pneumatic spring, a hydraulic spring, etc. In this embodiment, the third elastic element 476 is a spring.

[0154] When it is necessary to wind up the drawstring 465, turn the knob 473 so that the driving rotating shaft 471 rotates in the first direction. Under the action of the fixed limiting wheel 474 and the moving limiting wheel 475, the winding drum 472 cannot rotate in the second direction. Therefore, the drawstring 465 will not be released. When it is necessary to release the drawstring 465, pull the moving limiting wheel 475 through the operating handle 477 so that the moving limiting wheel 475 is separated from the fixed limiting wheel 474, thereby enabling the winding drum 472 to rotate in the second direction and releasing the drawstring 465.

[0155] As Figure 1 、 2 shown in FIGS. 16, the flushing assembly includes a flushing head 510, a water pipe 520, a first control valve 530, and a water pump 540.

[0156] Among them, the flushing head 510 is arranged on the machine body 100, and the flushing head 510 is fixedly connected to the machine body 100. The first end of the water pipe 520 is connected to the water supply system, and the second end is connected to the flushing head 510. The first control valve 530 is arranged on the water pipe 520, and the first control valve 530 is used to control the on-off of the water pipe 520. The water pump 540 is arranged on the water pipe 520.

[0157] During flushing, the water pump 540 and the first control valve 530 are opened, and the clean water transported by the water supply system is transported to the flushing head 510, thereby cleaning the glass slide. After the cleaning is completed, the water pump 540 and the first control valve 530 are closed.

[0158] It should be noted that the water supply system can be a water tank, a water tank, an external clean water supply system, etc.

[0159] As Figure 1 、 2 shown in FIGS. 17, the air-drying assembly includes a blowing head 610, a filtering device 620, an air pipe 630, a second control valve 640, and an air pump 650.

[0160] The blowing head 610 is arranged on the machine body 100, and the blowing head 610 is fixedly connected to the machine body 100. The filtering device 620 is arranged on the machine body 100, and the filtering device 620 is fixedly connected to the machine body 100. The first end of the air pipe 630 is connected to the filtering device 620, and the second end is connected to the blowing head 610. The second control valve 640 is arranged on the air pipe 630, and the second control valve 640 is used to control the on-off of the air pipe 630. The air pump 650 is arranged on the air pipe 630. The electric heating element 330 is arranged in the blowing head 610, and the electric heating element 330 is used to heat the air.

[0161] In the description of the present invention, a large number of specific details are set forth. However, it is understood that embodiments of the present invention may be practiced without these specific details. In some instances, well-known methods, structures, and techniques have not been shown in detail so as not to obscure the understanding of this description.

[0162] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some or all of the technical features; and these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be covered by the scope of the claims and the description of the present invention.

Claims

1. A slide automatic staining device, characterized in that: It comprises a machine body and a dyeing vat, a heating component, a grabbing component, a timing component and a controller arranged on the machine body; Wherein, the controller is electrically connected to the heating component, the grabbing component and the timing component; There are three staining jars, which are arranged on the machine body and are used to store trypsin solution, physiological saline and dye solution respectively; The heating component is used to heat the corresponding dyeing vat and keep the dyeing vat at a preset temperature; The grabbing assembly is used to grab the target glass slide and transfer the target glass slide to a target position; The timing component is used to record the time information when the grabbing component places the target slide at the target position and transmit the time information to the controller. The controller converts the received information into a corresponding electrical signal to control the operating state of the grabbing component.

2. The automatic slide staining device according to claim 1, characterized in that: Also includes: A washing component, which is arranged on the machine body, the washing component is electrically connected to the controller, and the washing component is used to wash the target slide; as well as An air-drying component is arranged on the machine body, the air-drying component is electrically connected to the controller, and the air-drying component is used to blow dry the target slide glass.

3. The automatic slide staining device according to claim 1 or 2, characterized in that: The heating assembly comprises: There are three water baths, which are arranged on the machine body, and the dyeing tanks are arranged in the water baths accordingly; A temperature sensor, which corresponds to the water bath one by one, is arranged in the corresponding water bath, and is electrically connected to the controller; An electric heating element, which corresponds one to one with the water bath, is disposed in the corresponding water bath, and is electrically connected to the controller; Among them, the electric heating element is used to heat the liquid medium in the water bath, the temperature sensor is used to detect the temperature information of the liquid medium in the water bath and transmit the temperature information to the controller, and the controller is used to convert the received electrical signal into a corresponding control signal to control the operating state of the electric heating element.

4. The automatic slide staining device according to claim 3, characterized in that: The water bath comprises: a pot body, which is arranged on the machine body; and A supporting mechanism is arranged in the pot body, and is used to support the dyeing tank so that the dyeing tank is suspended in the water bath pot.

5. The automatic slide staining device according to claim 4, characterized in that: The supporting mechanism comprises: A support ring connected to the inner side wall of the pot body; A support element is arranged obliquely, and the top end of the support element is closer to the axis of the support ring, the support element is hinged to the support ring, and a plurality of the support elements are provided, and the plurality of the support elements are arranged in sequence and spaced around the axis of the support ring; and The first elastic element is arranged on the supporting ring. In a natural state, the first elastic element applies elastic force to the supporting element so that the top end of the supporting element tends to move toward the direction close to the axis of the supporting ring.

6. The automatic slide staining device according to claim 5, characterized in that: The support mechanism also includes: A guide ring, which is coaxially arranged with the support ring and fixedly connected to the support ring; and A guide element, whose bottom end is hinged to the top end of the support element, and whose upper end is movably connected to the guide ring. The guide element is arranged at an angle, and the distance between the bottom end of the guide element and the axis line of the guide ring is relatively close. When the dyeing vat is placed, the dyeing vat can apply a force to the support element through the guide element to drive the top end of the support element to move in a direction away from the axis line of the support ring.

7. The automatic slide staining device according to any one of claims 1, 2, 4, 5 or 6, characterized in that: The grabbing component comprises: A sliding seat, which is slidably connected to the body, and the sliding seat can perform reciprocating linear motion between a first position and a second position in a lateral direction; A first driving mechanism, which is arranged on the machine body, and is used to drive the sliding seat to perform reciprocating linear motion between the first position and the second position, and is capable of keeping the sliding seat at a target position; A lifting seat, which is arranged below the sliding seat, and the lifting seat is slidably connected to the sliding seat so that the lifting seat can move up and down in the longitudinal direction; a second driving mechanism, which is disposed on the sliding seat, and is used to drive the lifting seat to move up and down, and can keep the lifting seat at a target position; A rotating seat, which is arranged at the bottom of the lifting seat and is rotatably connected to the lifting seat; a third driving mechanism, which is disposed on the lifting seat, and is used to drive the rotating seat to rotate and can keep the rotating seat at a target position; A swing seat, which is arranged at the bottom of the rotating seat, and the top of the swing seat is hinged to the bottom of the rotating seat; a fourth driving mechanism, which is disposed on the rotating seat, and is used to drive the swing seat to swing back and forth within a preset angle β range, and is capable of keeping the swing seat at a target position; The grabbing mechanism is arranged at the bottom of the swing seat, and the grabbing mechanism has a grabbing state and a releasing state which can be switched to each other.

8. The automatic slide staining device according to claim 7, characterized in that: The grabbing mechanism comprises: A grabbing arm, wherein two grabbing arms are provided, the two grabbing arms are symmetrically arranged at the bottom of the swing seat, and the grabbing arms are slidably connected to the swing seat so that the two grabbing arms can move closer to or farther away from each other; and A driving structure is arranged on the swing seat, and the driving structure is used to drive the two grabbing arms to move closer to or away from each other.

9. The automatic slide staining device according to claim 8, characterized in that: The driving structure comprises: A slider, which is slidably disposed in the swing seat, and the slider can move in a direction close to or away from the grabbing arm; A first permanent magnet, which is fixedly embedded in the slider; A first electromagnet, which is fixedly disposed in the swing seat, and the first electromagnet has a different magnetic property on a side opposite to the first permanent magnet; a pull rope, which corresponds to the grabbing arm one by one, wherein a first end of the pull rope is connected to the grabbing arm and a second end of the pull rope is connected to the slider; and The second elastic element has two ends connected to the two grabbing arms respectively, and in a natural state, the second elastic element applies elastic force to the two grabbing arms so that the two grabbing arms tend to move away from each other.

10. The automatic slide staining device according to claim 9, characterized in that: The draw cord is made of elastic material; The gripping mechanism further comprises a winding structure, which is arranged on the sliding block and is used for winding or releasing the pull rope to change the extended length of the pull rope.

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