Sacral nerve multi-target collaborative stimulation system and parameter configuration method

Abstract

The invention relates to a sacral nerve multi-target collaborative stimulation system and a parameter configuration method, and the system comprises a stimulation electrode and a stimulator. The first end of the stimulating electrode is provided with a plurality of independent electrode branches, and the outer wall of each independent electrode branch is provided with a plurality of electrode contacts; when each independent electrode branch is implanted into the corresponding sacral nerve target point, the electrode contact can be in contact with the sacral nerve target point; the stimulator is connected with the second end of the stimulating electrode and is used for providing stimulating current for each independent electrode branch in the stimulating electrode; the stimulation current acts on the sacral nerve target point through the electrode contacts on the independent electrode branches. Through the sacral nerve stimulation system, the problem that the overall stimulation intensity of the sacral nerve stimulation system on the stimulated object is insufficient is solved.

Description

Technical Field

[0001] This application relates to the field of sacral nerve stimulation, and particularly to a sacral nerve multi-target collaborative stimulation system and a parameter configuration method. Background Art

[0002] The sacral nerve stimulation technology is a nerve regulation technology for treating refractory overactive bladder. By stimulating the sacral nerve 3 of the stimulation object through a stimulation system, abnormal nerve transmission is inhibited to achieve the purpose of inhibiting overactive bladder. In the related art, the common sacral nerve implantation target position is mainly the unilateral sacral nerve 3. However, this method alleviates the symptoms of the stimulated object to a certain extent, but there are still some stimulated objects who are insensitive to the sacral nerve 3 stimulation. If the stimulation system continues to maintain the stimulation parameters set for the general situation, it cannot meet the demand for stimulation intensity of this part of the individuals, resulting in insufficient overall stimulation intensity of the stimulation system for the stimulated object, thereby affecting the stimulation effect.

[0003] Currently, there is no effective solution to the problem of insufficient overall stimulation intensity of the sacral nerve stimulation system for the stimulated object in the related art. Summary of the Invention

[0004] The embodiments of this application provide a sacral nerve multi-target collaborative stimulation system and a parameter configuration method to at least solve the problem of insufficient overall stimulation intensity of the sacral nerve stimulation system for the stimulated object in the related art.

[0005] In a first aspect, the embodiments of this application provide a sacral nerve multi-target collaborative stimulation system, including: a stimulation electrode and a stimulator; The first end of the stimulation electrode has a plurality of independent electrode branches, and a plurality of electrode contacts are arranged on the outer wall of each independent electrode branch; when each independent electrode branch is implanted into the corresponding sacral nerve target position, the electrode contacts can contact the sacral nerve target position; The stimulator is connected to the second end of the stimulation electrode and is used to provide a stimulation current to each independent electrode branch in the stimulation electrode; the stimulation current acts on the sacral nerve target position through the electrode contacts on the independent electrode branch.

[0006] In some of the embodiments, the multi-target collaborative stimulation system further includes a programmer; The programmer is communicatively connected to the stimulator and is used to transmit the acquired initial stimulation parameters to the stimulator; The stimulator is further used to collect the nerve signal parameters of the sacral nerve target position and generate a signal comparison result according to the nerve signal parameters; The stimulator is also used to adjust the initial stimulation parameters according to the signal comparison result, generate optimized stimulation parameters, and based on the optimized stimulation parameters, provide a new stimulation current to the independent electrode branches.

[0007] In some embodiments, the programmer further includes a display and interaction module; The display and interaction module is used to obtain the input initial stimulation parameters, and display the stimulator status information and nerve signal parameters sent by the received stimulator.

[0008] In some embodiments, the second end of the stimulating electrode includes a plurality of end faces; a plurality of electrode contacts are arranged on each end face; when the second end of the stimulating electrode is connected to the stimulator, the electrode contacts can contact with the elastic contact pieces inside the stimulator.

[0009] In some embodiments, the second end of the stimulating electrode is further provided with a directional pointing marking component; The outer shell of the stimulator is also provided with an insertion direction indication marking component; Wherein, when the second end of the stimulating electrode is connected to the stimulator, the directional pointing marking component is adapted to the insertion direction indication marking component.

[0010] In some embodiments, the stimulating electrode includes a first stimulating electrode and a second stimulating electrode; The plurality of independent electrode branches of the first stimulating electrode, and / or the plurality of independent electrode branches of the second stimulating electrode are further provided with electrode barbs; Wherein, the distance between the position where the electrode barbs are located and the position where the plurality of electrode contacts are located is within a preset distance range.

[0011] In some embodiments, the stimulator includes a main control module and a stimulation acquisition module, the stimulation acquisition module includes a control unit, a stimulation unit and a switching unit, and the switching unit includes a first switching subunit; The main control module is used to generate a stimulation instruction indicating at least one first target electrode branch; the first target electrode branch is the branch among the respective independent electrode branches to which the stimulation current is to be applied; The control unit is used to determine a stimulating electrode contact from the electrode contacts on the first target electrode branch, and in response to the stimulation instruction, control the first switching subunit to connect the stimulation path where the stimulating electrode contact on the first target electrode branch is located; The stimulation unit is used to provide the stimulation current to the first target electrode branch through the stimulation path; the stimulation current acts on the sacral nerve target site through the stimulating electrode contact.

[0012] In some of these embodiments, the stimulus acquisition module further includes an acquisition unit, and the switching unit further includes a second switching subunit; The main control module is further configured to generate an acquisition instruction indicating at least one second target electrode branch; the second target electrode branch is a branch among the respective independent electrode branches for which nerve signal parameters are to be acquired; The control unit is configured to determine an acquisition electrode contact from the electrode contacts on the second target electrode branch, and in response to the acquisition instruction, control the second switching subunit to connect the acquisition path where the acquisition electrode contact is located; The acquisition unit is configured to receive, through the acquisition path, the nerve signal parameters of the sacral nerve target position acquired by the acquisition electrode contact.

[0013] In some of these embodiments, the switching unit further includes a third switching subunit; The third switching subunit is configured to switch the connection state between the stimulation path and the acquisition path.

[0014] In a second aspect, an embodiment of the present application provides a parameter configuration method, which is applied to the sacral nerve multi-target collaborative stimulation system as described in the first aspect above. The method includes: Obtain stimulation parameters, perform parameter configuration processing based on the stimulation parameters, and provide a stimulation current to at least one independent electrode branch of the stimulation electrode; the stimulation current acts on the sacral nerve target position through the electrode contacts on the independent electrode branch.

[0015] Compared with the related art, the sacral nerve multi-target collaborative stimulation system and parameter configuration method provided by the embodiments of the present application. The system includes: a stimulation electrode and a stimulator; the first end of the stimulation electrode has a plurality of independent electrode branches, and a plurality of electrode contacts are provided on the outer wall of each independent electrode branch; when each independent electrode branch is implanted into the corresponding sacral nerve target position, the electrode contacts can contact the sacral nerve target position; the stimulator is connected to the second end of the stimulation electrode and is configured to provide a stimulation current to each independent electrode branch in the stimulation electrode; the stimulation current acts on the sacral nerve target position through the electrode contacts on the independent electrode branch.

[0016] Based on this, the combined stimulation of the sacral nerve at multiple target positions is realized, avoiding the problem that in some patients, the sacral nerve stimulation system has insufficient overall stimulation intensity for the stimulated object due to insensitivity during single-nerve stimulation. At the same time, the accuracy and reliability of the stimulation current delivery during multi-target collaborative stimulation are ensured, effectively improving the treatment efficiency of the sacral nerve regulation mechanism.

[0017] Details of one or more embodiments of the present application are set forth in the following drawings and description to make other features, objects, and advantages of the present application more concise and understandable. Description of the Drawings

[0018] The drawings described herein are used to provide a further understanding of the present application and form a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation of the present application. In the drawings: Figure 1 is a hardware structure block diagram of a terminal for a parameter configuration method according to an embodiment of the present application; Figure 2 is a structure block diagram of a sacral nerve multi-target collaborative stimulation system according to an embodiment of the present application; Figure 3 is a schematic structural diagram of a stimulation electrode according to an embodiment of the present application; Figure 4 is a schematic structural diagram of a stimulation acquisition module according to an embodiment of the present application; Figure 5 is a schematic structural diagram of a switching unit according to an embodiment of the present application; Figure 6 is a schematic structural diagram of a multi-target collaborative stimulation system according to an embodiment of the present application; Figure 7 is a structure block diagram of a multi-target collaborative stimulation system according to an embodiment of the present application; Figure 8 is a schematic structural diagram of another stimulation electrode according to an embodiment of the present application; Figure 9A is a schematic diagram of a connection structure between a stimulation electrode and a stimulator according to an embodiment of the present application; Figure 9B is Figure 9A the internal structure diagram of the part where the stimulation electrode is connected to the stimulator; Figure 10 is a schematic diagram of a stimulation electrode implanted at a sacral nerve target position according to an embodiment of the present application. Detailed Embodiments

[0019] In order to make the objectives, technical solutions and advantages of the present application clearer and more understandable, the present application will be described and explained below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application. All other embodiments obtained by those of ordinary skill in the art based on the embodiments provided in the present application without making creative efforts fall within the scope of protection of the present application. In addition, it can also be understood that although the efforts made in this development process may be complex and lengthy, for those of ordinary skill in the art related to the content disclosed in the present application, some design, manufacturing or production changes based on the technical content disclosed in the present application are only conventional technical means and should not be understood as insufficient disclosure of the content of the present application.

[0020] The mention of "embodiment" in the present application means that the specific features, structures or characteristics described in conjunction with the embodiment can be included in at least one embodiment of the present application. The appearance of this phrase in various positions in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those of ordinary skill in the art explicitly and implicitly understand that the embodiments described in the present application can be combined with other embodiments without conflict.

[0021] Unless otherwise defined, the technical terms or scientific terms involved in the present application should be of the ordinary meaning understood by those of ordinary skill in the technical field to which the present application belongs. The words such as "a", "one", "kind", "the" and the like involved in the present application do not indicate a limitation in quantity and can represent a singular or plural number. The terms "including", "comprising", "having" and any variations thereof involved in the present application are intended to cover non-exclusive inclusion; for example, a process, method, system, product or device including a series of steps or modules (units) is not limited to the listed steps or units, but may further include unlisted steps or units, or may further include other steps or units inherent to these processes, methods, products or devices. The terms "connected", "coupled" and the like involved in the present application are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. The "plurality" involved in the present application means greater than or equal to two. "And / or" describes the association relationship of associated objects and indicates that three relationships may exist. For example, "A and / or B" may represent: A exists alone, A and B exist simultaneously, and B exists alone. The terms "first", "second", "third" and the like involved in the present application are only used to distinguish similar objects and do not represent a specific order for the objects.

[0022] The method embodiment provided in this embodiment can be executed on a terminal, a computer or a similar computing device. Taking running on a terminal as an example,Figure 1 It is a hardware structure block diagram of a terminal for a parameter configuration method according to an embodiment of the present application. As Figure 1 shown, the terminal may include one or more ( Figure 1 only one is shown in the figure) processors 102 (the processor 102 may include, but is not limited to, a processing device such as a microprocessor MCU or a programmable logic device FPGA) and a memory 104 for storing data. Optionally, the above terminal may further include a transmission device 106 for communication functions and an input / output device 108. Those of ordinary skill in the art can understand that Figure 1 the structure shown is only schematic and does not limit the structure of the above terminal. For example, the terminal may further include more or fewer components than Figure 1 shown in the figure, or have a different configuration from Figure 1 shown in the figure.

[0023] The memory 104 can be used to store computer programs. For example, software programs and modules of application software, such as the computer program corresponding to the parameter configuration method in the embodiment of the present application. The processor 102 executes various functional applications and data processing by running the computer program stored in the memory 104, that is, implements the above method. The memory 104 may include a high-speed random access memory, and may further include a non-volatile memory, such as one or more magnetic storage devices, flash memories, or other non-volatile solid-state memories. In some instances, the memory 104 may further include a memory remotely provided with respect to the processor 102, and these remote memories may be connected to the terminal through a network. Examples of the above network include, but are not limited to, the Internet, an enterprise intranet, a local area network, a mobile communication network, and combinations thereof.

[0024] The transmission device 106 is used to receive or send data via a network. Specific examples of the above network may include a wireless network provided by a communication provider of the terminal. In one instance, the transmission device 106 includes a network adapter (abbreviated as NIC), which can be connected to other network devices through a base station and thus can communicate with the Internet. In one instance, the transmission device 106 may be a radio frequency (abbreviated as RF) module, which is used to communicate with the Internet wirelessly.

[0025] It should be noted that in the related art, the common sacral nerve implantation point is mainly the unilateral S3 nerve. However, considering that the three branches of the sacral nerve, namely the S2, S3, and S4 nerves, are all components of the lower urinary tract nerves, it is difficult to treat all abnormal conditions in the six nerve branches of the bilateral S2, S3, and S4 nerves by stimulating only the S3 nerve; the existing sacral nerve stimulation systems with a single implantation point cannot provide more treatment options, resulting in insufficient overall stimulation intensity of the sacral nerve stimulation system for the stimulated object.

[0026] Based on this, the present embodiment provides a sacral nerve multi-target cooperative stimulation system. Figure 2 It is a structural block diagram of a sacral nerve multi-target cooperative stimulation system according to an embodiment of the present application, as Figure 2 shown. The system includes: a stimulating electrode 22 and a stimulator 21.

[0027] The first end of the stimulating electrode 22 has a plurality of independent electrode branches 221, and a plurality of electrode contacts 222 are arranged on the outer wall of each independent electrode branch 221; when each independent electrode branch 221 is implanted into the corresponding sacral nerve target point, the electrode contacts 222 can contact the sacral nerve target point.

[0028] The first end of the above-mentioned stimulating electrode 22 refers to the end that first enters the body of the stimulated object when the stimulating electrode 22 is implanted into the sacral nerve target point, which can be regarded as the distal end of the stimulating electrode. Among them, the number of stimulating electrodes 22 and the number of independent electrode branches 221 included in each stimulating electrode can be configured according to actual needs. For example, if it is necessary to stimulate at most the six nerves of the bilateral S2, S3, and S4 nerves, the stimulating electrode 22 can be set to two stimulating electrodes, and each first end of the stimulating electrode 22 is respectively provided with three independent electrode branches 221, a total of six independent electrode branches 221; in this way, when the system works, the six independent electrode branches 221 can be respectively implanted at the S2, S3, and S4 hole positions on the left and right sides (i.e., the above-mentioned sacral nerve target points) to cooperatively stimulate these six nerves. Or, the stimulating electrode 22 can also be set to three stimulating electrodes 22, and each first end of the stimulating electrode 22 is respectively provided with two independent electrode branches 221, or the first section of a stimulating electrode 22 is set to six independent electrode branches 221, which is not limited here. It should also be understood that although multiple independent electrode branches 221 are designed in this embodiment, if only some nerves need to be stimulated during actual work, the corresponding partial independent electrode branches 221 can be directly implanted into the target points where the nerves to be stimulated are located, and the other independent electrode branches 221 can be left hanging, or the openings of the other stimulating electrodes 22 that do not need to be implanted into the body of the stimulated object can be sealed.

[0029] A plurality of electrode contacts 222 are arranged on the outer wall of each independent electrode branch 221 at intervals along the electrode branch leads; the distances between the electrode contacts 222 can be the same or different. The number of electrode contacts 222 is not limited, and at least two are required. Each contact can be used as a stimulation and acquisition contact, and the two are switched for use. Specifically, if the number of electrode contacts 222 arranged on each independent electrode branch 221 is two, then during the actual operation, through these two electrode contacts 222, two processes of applying a stimulation current to the sacral nerve target site and collecting nerve signals can be switched. For example, during the stimulation phase, contact 0 is used as the anode (+) and contact 1 is used as the cathode (-) to apply a stimulation current; during the acquisition phase, the stimulation circuit is disconnected, and through contact 0 / 1, the electrophysiological signals of the sacral nerve root or surrounding tissues are collected. Or the number of electrode contacts 222 arranged on each independent electrode branch 221 can be appropriately increased to work through different contact combinations.

[0030] Specifically, please refer to Figure 3 , which shows a schematic structural diagram of a stimulation electrode; the first end of the stimulation electrode has three independent electrode branches 221, respectively represented as branch a, branch b, and branch c. The top of each independent electrode branch 221 is successively arranged with 6 equally spaced electrode contacts 222. Taking branch a implanted at the target site of the S2 nerve on one side as an example, when the stimulation current output by the stimulator is transmitted to branch a, the stimulation current acts on the S2 nerve target site through two of these 6 electrode contacts 222 (contact 0 and contact 1), or the nerve signal parameters of the S2 nerve target site are collected through two other electrode contacts (contact 2 and contact 3) among the 6 electrode contacts 222 of branch a. In addition, the remaining two contacts (contact 4 and contact 5) in branch a can be used as alternative contacts to participate in the operation.

[0031] The above-mentioned stimulator 21 is connected to the second end of the stimulation electrode 22 and is used to provide a stimulation current to each independent electrode branch 221 in the stimulation electrode 22; the stimulation current flows through the electrode contacts 222 on the independent electrode branch 221 and acts on the sacral nerve target site. Among them, the second end of the stimulation electrode 22 is the other end opposite to the first end of the above-mentioned stimulation electrode 22, and can also be regarded as the electrode proximal end relatively close to the stimulator 21.

[0032] The output port of the stimulator 21 is rigidly connected to the second end of the stimulating electrode 22. When the stimulator 21 applies a stimulus, the stimulating electrode 22 and one or more sacral nerve target points to which the stimulus is to be applied are predetermined, and the stimulator 21 outputs a stimulating current that meets the preset stimulus parameter configuration. The stimulating current flows from the second end of the stimulating electrode 22 at the connection point, through the first end of the stimulating electrode 22, and is transmitted to one or more independent electrode branches 221 corresponding to the sacral nerve target points to which the stimulus is to be applied. Finally, it acts on the sacral nerve target points through the electrode contacts 222 provided on the independent electrode branches 221 to stimulate the sacral nerves at these points. Therefore, during the process of the above-mentioned stimulator 21 applying a stimulus to the sacral nerves, in the above-mentioned manner, a single independent electrode branch 221 can apply a stimulating current to a certain sacral nerve target point, or multiple independent electrode branches 221 can be used simultaneously to co-stimulate multiple sacral nerve target points, thereby effectively improving the overall stimulating intensity of the sacral nerves of the stimulated object.

[0033] Thus, considering the synergistic effect of the S2, S3, and S4 nerves in regulating various muscles and tissues of the lower urinary tract system, the system is configured with six independent stimulating electrodes 22 that act on the left and right S2, S3, and S4 nerves respectively. By independently or jointly stimulating the six nerve branches, the purpose of treating overactive bladder is achieved. At the same time, considering the mutual influence of the S2, S3, and S4 nerves, when the system stimulates one of the six nerves, it can collect nerve signals from the remaining nerve branches to observe the influence of the stimulated nerve branch on other nerve branches, providing more information for the system to co-stimulate the S2, S3, and S4 nerves.

[0034] In the above-mentioned sacral nerve multi-target co-stimulation system, by providing multiple independent electrode branches 221 at the first end of the stimulating electrode 22, each independent electrode branch 221 is implanted into different sacral nerve target points, and the stimulator 21 provides the stimulating current transmitted to each independent electrode branch 221. Finally, the stimulating current is applied to the corresponding sacral nerves through each independent electrode branch 221, thus realizing a combined stimulation scheme for the sacral nerves of multiple target points, avoiding the problem of insufficient overall stimulating intensity of the stimulating system for the stimulated object caused by the insensitivity of some patients to single-nerve stimulation and the fact that the stimulating system can only apply current stimulation to a single nerve. At the same time, it also ensures the accuracy and reliability of the transmission of the stimulating current during multi-target co-stimulation, effectively improving the treatment efficiency of the sacral nerve regulation mechanism.

[0035] In some of the embodiments, the above-mentioned stimulator includes a main control module and a stimulation acquisition module. The stimulation acquisition module includes a control unit, a stimulation unit, and a switching unit. The switching unit includes a first switching subunit; The main control module is used to generate a stimulation instruction indicating at least one first target electrode branch; the first target electrode branch is the branch among the individual independent electrode branches to which a stimulation current is to be applied, and the electrode contacts on each independent electrode branch can be configured as stimulation electrode contacts; the control unit is used to determine the stimulation electrode contacts from the electrode contacts on the first target electrode branch, and in response to the stimulation instruction, control the first switching subunit to turn on the stimulation path where the stimulation electrode contacts on the first target electrode branch are located; the stimulation unit is used to provide a stimulation current to the first target electrode branch through the stimulation path; the stimulation current acts on the sacral nerve target site via the stimulation electrode contacts.

[0036] Among them, the main control module, as the system command center, is responsible for parsing treatment parameters (such as stimulation frequency, pulse width, amplitude) and electrode distribution information, and generating a stimulation instruction containing one or more target electrode branch identifiers. For example, when it is necessary to activate the left sacral nerve S3 segment, the main control module designates an independent electrode branch as the first target electrode branch and generates a corresponding stimulation parameter packet. After receiving the instruction, the control unit in the stimulation acquisition module randomly selects two electrode contacts from the first target electrode branch as the stimulation electrode contacts, or selects the default two electrode contacts as the stimulation electrode contacts, and parses the physical position of the target electrode branch through the address decoder to drive the multiplexer array in the first switching subunit. This subunit uses a high-precision relay matrix, which can quickly close the path where the target stimulation electrode contacts are located and simultaneously disconnect other non-target paths to avoid current leakage. The stimulation unit is designed based on a constant current source, and monitors the output current in real time through a feedback loop to ensure the stability of the stimulation amplitude. After the path is turned on, the stimulation unit generates square wave or triangular wave current pulses according to the preset parameters, and directly acts on the sacral nerve target site via the stimulation electrode contacts. The current waveform can be dynamically adjusted by the main control module to simulate the time-domain characteristics of natural nerve signals (such as the bursting discharge mode).

[0037] For example, when the stimulation unit is working, the stimulation electrodes and the stimulation target sites are determined in advance. The operator can choose between two modes: multi-nerve branch stimulation and single-nerve branch stimulation, and make a judgment specifically according to the clinical effect. During single-nerve branch stimulation, the operator can choose the electrodes corresponding to the S2, S3, and S4 nerves of the sacrum respectively, and then select two of the contacts as the positive and negative poles of the stimulation respectively. During multi-nerve branch stimulation, the operator can simultaneously select two to six nerve branches for stimulation and configure the positive and negative poles of the stimulation sites of each electrode branch.

[0038] Through the above embodiments, a hierarchical architecture of a main control module and a stimulation acquisition module (including a control unit, a stimulation unit, and a switching unit) is provided. The main control module generates dynamic stimulation instructions to drive the control unit and the stimulation unit in the stimulation acquisition module to work together, and finally, the switching unit delivers the stimulation current to the target electrode branch directionally, so as to achieve precise electrical stimulation of the sacral nerve target site.

[0039] In some of these embodiments, the above stimulation acquisition module further includes an acquisition unit, and the switching unit further includes a second switching subunit; the main control module is further configured to generate an acquisition instruction indicating at least one second target electrode branch; the second target electrode branch is a branch among the individual independent electrode branches for which the nerve signal parameters are to be acquired, and the electrode contacts on each individual independent electrode branch can be configured as acquisition electrode contacts; the control unit is configured to determine the acquisition electrode contacts from the electrode contacts on the second target electrode branch and, in response to the acquisition instruction, control the second switching subunit to connect the acquisition path where the acquisition electrode contacts on the second target electrode branch are located; the acquisition unit is configured to receive, through the acquisition path, the nerve signal parameters of the sacral nerve target site acquired by the acquisition electrode contacts.

[0040] Specifically, as the system command center, the main control module has added an acquisition instruction generation function. When it is necessary to acquire the nerve signal parameters of the sacral nerve target site, the main control module designates the second target electrode branch (such as S4) in the independent electrode branches and generates an acquisition instruction including acquisition parameters (such as sampling rate, filtering range). For example, when evaluating the stimulation effect, the main control module can simultaneously designate the left S3 as the stimulation electrode branch and the right S4 as the acquisition electrode branch to achieve "stimulation - acquisition" synchronous operation.

[0041] The control unit in the stimulation acquisition module randomly selects two electrode contacts from the second target electrode branch as the acquisition electrode contacts, or selects the default two electrode contacts as the acquisition electrode contacts, and after responding to the acquisition instruction, drives the multiplexer array in the second switching subunit. This subunit uses a relay matrix independent of the first switching subunit, which can quickly close the acquisition path where the target acquisition electrode contacts are located and simultaneously disconnect other non - target paths to avoid signal interference. The acquisition unit is designed based on a high - precision analog front - end, and receives, through the acquisition path, the nerve signal parameters (such as amplitude, frequency, spectral density) of the sacral nerve target site acquired by the acquisition electrode contacts. The acquisition unit is built - in with a programmable gain amplifier and an anti - aliasing filter, supports multi - channel synchronous acquisition, and can transmit the raw data to the main control module for real - time analysis.

[0042] For example, when the acquisition unit is working, the acquisition electrodes and acquisition sites are determined in advance. The operator can choose between two modes: multi-nerve branch acquisition and single-nerve branch acquisition. During single-nerve acquisition, the operator can select one of the left and right S2, S3, and S4 nerves, and then select two sites of its corresponding electrode as the positive and negative electrodes for acquisition respectively. During multi-nerve branch acquisition, the operator can simultaneously select two to six nerve branches for acquisition and configure the positive and negative electrodes for the acquisition sites of each electrode branch.

[0043] When the stimulation and acquisition work simultaneously, when different electrode branches perform stimulation and acquisition respectively, taking the example of stimulating with the a branch of Electrode 1 and acquiring with the b branch of Electrode 1 (or the a branch of Electrode 2), first select two sites of the a electrode as the positive and negative electrodes for stimulation respectively, and then select two sites of the b (or the a branch of Electrode 2) electrode branch as the positive and negative electrodes for acquisition respectively. In addition, the system supports a mode where multiple stimulation electrodes and multiple acquisition electrodes work simultaneously. When the same electrode branch performs stimulation and acquisition respectively, taking the example of performing acquisition and stimulation with the a branch of Electrode 1, first select two of the six contacts of the a branch as the positive and negative electrodes for stimulation, and then select two of the remaining four contacts of the a branch as the positive and negative electrodes for acquisition.

[0044] Through the above embodiments, the acquisition unit and the second switching subunit are introduced. The main control module generates dual-mode instructions (stimulation instructions and acquisition instructions) to drive the control unit, stimulation unit, and acquisition unit in the stimulation acquisition module to work together. Finally, the switching unit realizes the independent switching and efficient reuse of the stimulation path and the acquisition path, thereby constructing a "stimulation - acquisition" dual-path collaborative mechanism and achieving dynamic monitoring and precise regulation of the sacral nerve target points.

[0045] In some of these embodiments, the above switching unit further includes a third switching subunit; the third switching subunit is used to switch the connection state between the stimulation path and the acquisition path. Among them, the hardware implementation of the third switching subunit can be based on a high-speed analog switch matrix, which internally includes an independent stimulation path control group and an acquisition path control group, and each control group is composed of multiple high-speed switch pairs. The main control module sends a path switching instruction to the third switching subunit, and the instruction contains the target electrode branch number and the target path type (stimulation / acquisition). The first switching subunit and the second switching subunit respectively manage the primary switching of the stimulation path and the acquisition path, while the third switching subunit is responsible for dynamically connecting between the two. For example, when it is necessary to stimulate contacts 0 and 1, the main control module first opens the two paths of 0 and 1 in the first switching subunit, and at the same time instructs the third switching subunit to connect contacts 0 and 1 to the stimulation path. In the scenario of synchronous stimulation and acquisition, the third switching subunit can manage the connection states of multiple contacts at the same time. For example, when contacts 0 and 1 are used for stimulation and contacts 2 and 3 are used for acquisition, the third switching subunit connects 0 and 1 to the stimulation path and contacts 2 and 3 to the acquisition path. The same contact can be alternately used for stimulation and acquisition operations, and different contacts can work synchronously or asynchronously; for example, after contact 0 completes stimulation, the third switching subunit can quickly switch it to the acquisition path, while contacts 1, 2, and 3 can continue other operations.

[0046] Through the above embodiments, a third switching subunit is further introduced, and a dynamic switching mechanism between the stimulation path and the acquisition path is constructed. Through the dynamic switching of the third switching subunit, the same contact can be reused as a stimulation contact or an acquisition contact, reducing the hardware resource overhead, realizing the isolation of the stimulation path and the acquisition path at the hardware level, avoiding the direct interference of the stimulation current on the acquisition signal, and being able to support the quick switching of any contact between the stimulation and acquisition modes, thus contributing to the flexible reuse of electrode resources and the significant improvement of system efficiency.

[0047] Please refer to Figure 4, the above-mentioned stimulation acquisition module is divided into six independent stimulation units, six independent acquisition units, and six switching units. Among them, the electrode 1 stimulation unit includes the stimulation units corresponding to the three independent electrode branches of electrode 1 (stimulation 1-0, stimulation 1-1, and stimulation 1-2); the electrode 2 stimulation unit includes the stimulation units corresponding to the three independent electrode branches of electrode 2 (stimulation 2-0, stimulation 2-1, and stimulation 2-2); the electrode 1 acquisition unit includes the acquisition units corresponding to the three independent electrode branches of electrode 1 (acquisition 1-0, acquisition 1-1, and acquisition 1-2); the electrode 2 acquisition unit includes the acquisition units corresponding to the three independent electrode branches of electrode 2 (acquisition 2-0, acquisition 2-1, and acquisition 2-2). One stimulation unit, one acquisition unit, and one switching unit are responsible for the stimulation and acquisition of six contacts of one electrode branch. For example, stimulation 1-0 and acquisition 1-0, plus one switching unit are responsible for the work of six contacts of branch a of electrode 1; stimulation 2-2 and acquisition 2-2, plus one switching unit are responsible for the work of six contacts of branch c of electrode 2. These six sub-modules work independently of each other and can work synchronously or asynchronously. Among them, each stimulation site of each independent branch of the sacral nerve stimulation electrode has both stimulation and acquisition functions. The stimulation and acquisition functions of the stimulation sites on the same independent branch work alternately, and the stimulation and acquisition functions of the stimulation sites on different independent branches can work synchronously or alternately.

[0048] Further, please refer to Figure 5, the above-mentioned switching unit is divided into a first switching subunit (i.e., the stimulation switching subunit for controlling the stimulation path), a second switching subunit (i.e., the acquisition switching subunit for controlling the acquisition path), and six third switching subunits (i.e., the stimulation and acquisition switching subunits). Taking stimulation 2-2 and acquisition 2-2 and their acquisition-stimulation switching combination module as an example, stimulation 2-2 is connected to a stimulation switching module, acquisition 2-2 is connected to an acquisition switching module, the stimulation switching module and the acquisition switching module are sequentially connected to 6 acquisition-stimulation switching modules, and the 6 acquisition-stimulation switching modules are connected to 6 contacts on the c branch of electrode 2. The stimulation switching module, the acquisition switching module, and the acquisition-stimulation switching module are all controlled by the acquisition and stimulation control module. At the same time, the acquisition and stimulation control module can open two paths of a stimulation switching module and an acquisition switching module, and open one path of an acquisition-stimulation switching module. When only stimulating, taking the opening of contacts 0 and 1 as an example, the acquisition and stimulation control module opens two paths of 0 and 1 in the stimulation switching module, and at the same time opens the stimulation paths corresponding to contacts 0 and 1 in the acquisition and stimulation control module; when only acquiring, taking the opening of contacts 0 and 1 as an example, the acquisition and stimulation control module opens two paths of 0 and 1 in the acquisition switching module, and at the same time opens the acquisition paths corresponding to contacts 0 and 1 in the acquisition and stimulation switching module; when stimulating and acquiring synchronously, taking the stimulation of contacts 0 and 1 and the acquisition of contacts 2 and 3 as an example, the acquisition and stimulation control module opens two paths of 0 and 1 in the stimulation switching module, two paths of 2 and 3 in the acquisition switching module, and at the same time opens the stimulation paths corresponding to contacts 0 and 1 in the acquisition and stimulation switching module, and the acquisition paths corresponding to contacts 2 and 3 in the acquisition and stimulation switching module; stimulation and acquisition of the same contact can be alternated, and stimulation and acquisition of different contacts can be synchronous or asynchronous.

[0049] In some of the embodiments, the above-mentioned sacral nerve multi-target cooperative stimulation system further includes a programmer; the programmer is communicatively connected to the stimulator and is used to transmit the obtained initial stimulation parameters to the stimulator. As the control end of the system, the programmer establishes a communication connection with the stimulator, and its main function is to transmit the obtained initial stimulation parameters to the stimulator to realize the initial setting of the stimulation parameters of the stimulator. Please refer to Figure 6 , the figure shows a schematic structural diagram of the sacral nerve multi-target cooperative stimulation system. In this system, wireless communication transmission is carried out between the programmer and the stimulator. This communication method has the advantages of high flexibility and convenient installation, avoiding problems such as complex wiring and limited movement that may be brought by wired connection, making the system more convenient and adaptable in practical applications. It should also be added that the wireless communication link between the above-mentioned programmer and the stimulator can adopt a star network topology structure, and the programmer is used as the main node to communicate with multiple stimulators synchronously or asynchronously.

[0050] The above-mentioned stimulator is also used to collect the neural signal parameters of the sacral nerve target site and generate a signal comparison result based on the neural signal parameters. The stimulator is also used to adjust the initial stimulation parameters according to the signal comparison result, generate optimized stimulation parameters, and provide a new stimulation current to the independent electrode branches based on the optimized stimulation parameters. Among them, the stimulator, as the core execution component of the system, undertakes multiple key tasks. On the one hand, it receives the initial stimulation parameters transmitted by the programmer; on the other hand, it collects the neural signal parameters of the sacral nerve target site, generates a signal comparison result based on these parameters, and the neural signal parameters used for signal comparison can include amplitude, frequency, spectral density, and time-frequency information, etc.; and, adjusts the initial stimulation parameters according to the result, generates optimized stimulation parameters, and then provides a new stimulation current to the independent electrode branches.

[0051] More specifically, the stimulator is connected to multiple independent electrode branches, which are respectively implanted into different target sites of the sacral nerve (such as the S3 / S4 sacral foramina), and coordinated stimulation is achieved through different contact combinations. For example, a six-contact electrode can provide 30 stimulation combination schemes, significantly improving the regulation accuracy. In addition, the stimulator is built-in with a neural signal acquisition unit (such as a bioelectric potential amplifier and an analog-to-digital converter) to obtain the neuroelectrophysiological signals (such as amplitude, frequency, spectral density, and time-frequency information, etc.) of the target site in real time, and generates a signal comparison result through an embedded algorithm (such as threshold comparison, machine learning model) to evaluate the neural response state, and then dynamically adjusts the stimulation parameters according to the signal characteristics to improve the stimulation effect and avoid over-stimulation.

[0052] The following further describes the process of adjusting the initial stimulation parameters based on the signal comparison result: First, for each independent electrode branch, calculate the correlation between its parameters such as amplitude, frequency, spectral density, and time-frequency information. For example, calculate the Pearson correlation coefficient between the amplitude and frequency of electrode branch 1-a, and the mutual information between the spectral density and time-frequency information. Compare the corresponding parameters between different independent electrode branches. For example, compare the amplitude-frequency correlation and spectral density-time-frequency information correlation between electrode branch 1-a and branch 1-b. Next, according to the preset correlation threshold, judge whether the signal parameter correlation of each independent electrode branch is better than that of other branches. For example, set the correlation threshold to 0.8. If the amplitude-frequency correlation coefficient of electrode branch 1-a is greater than 0.8 and higher than the corresponding correlation coefficient of branch 1-b, it is determined that the signal parameter correlation of branch 1-a is better than that of branch 1-b. Considering the correlation comparison results of multiple parameters comprehensively, determine the overall signal quality of each independent electrode branch. For example, if branch 1-a is better than branch 1-b in the correlation comparison of multiple parameters such as amplitude, frequency, spectral density, and time-frequency information, it can be considered that the overall signal quality of branch 1-a is better.

[0053] It should also be noted that the above signal comparison process can be specifically executed by the signal comparison unit included in the stimulation acquisition module of the stimulator. Please refer to Figure 4 , the stimulation acquisition module further includes a signal comparison unit, and may also include a parameter scanning unit and a signal processing unit. For example, the sacral nerve signals collected by the electrode 2 acquisition unit are sent to the second signal processing unit, and the second signal processing unit processes the signals such as de-linearization and power frequency filtering. The processed data is further sent to the second signal comparison unit, and the stimulation parameter scanning module also sends the stimulation parameters to the second signal comparison unit. The second signal comparison unit compares the processed nerve signals on the three branches of the electrode 2, and returns the optimized stimulation parameters to the control unit of the stimulation acquisition module. The first signal comparison unit and the second signal comparison unit may further send the data to the third signal comparison unit, and the signal comparison unit compares the signals collected by the two electrodes, optimizes the bilateral stimulation parameters, and returns them to the control unit. The first signal processing unit and the second signal processing unit may also directly send the processed data to the main control module, and the main control module sends it to the programmer for relevant technical personnel to perform data analysis.

[0054] Through the above embodiments, the sacral nerve multi-target collaborative stimulation system has achieved a leap from static parameter setting to dynamic adaptive adjustment, realizing dynamic optimization of stimulation parameters, which is beneficial to improving the treatment effect and safety.

[0055] In some of these embodiments, the above programmer further includes a display and interaction module; the display and interaction module is used to obtain the input initial stimulation parameters, and display the stimulator status information and nerve signal parameters sent by the received stimulator.

[0056] The display and interaction module provides a convenient parameter input interface for users. The module may also have a built-in parameter verification mechanism to check the format, range, and rationality of the parameters in real time during the user input process. If the input does not meet the requirements, such as the parameter exceeds the set range or the format is incorrect, the system will immediately pop up a prompt message to guide the user to make corrections. When the parameter input is completed, the user clicks the confirmation button, and the module packages the input parameters and transmits the parameters accurately and stably to the stimulator through the communication protocol with the stimulator, providing the basic settings for subsequent stimulation treatment.

[0057] And during the actual working process, the display interaction module maintains real-time communication with the stimulator and continuously receives the status information sent by the stimulator. This information covers the operating status of the stimulator (such as normal operation, standby, failure, etc.), connection status (connection successful, connection failed, connection interrupted), and battery status (remaining battery level, charging status), etc. The display interaction module can also display this information in a way that combines graphics and text. Through different icons, colors, and text descriptions, users can quickly and intuitively understand the current status of the stimulator. For example, a green icon indicates normal operation, and a red icon indicates a failure. At the same time, the display interaction module will update the status information in real time to ensure that the information obtained by the user is always the latest.

[0058] Through the above embodiments, efficient interaction with the user and the stimulator is achieved, providing an important guarantee for the stable operation and precise treatment of the multi-target collaborative stimulation system.

[0059] It should also be noted that, please refer to Figure 7 , in addition to the above display interaction module, the above-mentioned programmer can also include a battery module, an MCU module, and a wireless communication module. The MCU module is used to receive the control input from the display interaction module, send it to the wireless communication module, receive the signal from the wireless communication module, and transfer it to the display interaction module; the display interaction module is used to input stimulation acquisition commands and parameters, and display the system status and stimulation acquisition parameters; the wireless communication module is used to receive the instructions from the MCU and send them to the stimulator, and receive the signals from the stimulator; the battery module supplies power to other parts of the programmer.

[0060] In addition, please refer to Figure 7 , the stimulator includes a stimulation acquisition module, a main control module, a wireless communication module, and a wireless charging module. The stimulation acquisition module is used to configure the stimulation and acquisition channels, output stimulation according to the specified stimulation parameters, and collect nerve signals at each site according to the instructions; the main control module is used to receive and process the signals from the wireless communication module, send the stimulation commands and parameters, and the acquisition commands to the stimulation acquisition module, receive the collected data, and send it to the wireless communication module. The wireless communication module is used to communicate with the programmer, receive or send information to the programmer. The wireless charging module is used to charge the internal battery, and the internal battery supplies power to other modules of the stimulator. Among them, the stimulation parameters of the stimulator and the programmer include but are not limited to frequency, pulse width, stimulation waveform, amplitude, voltage / current mode, etc.

[0061] In some of the embodiments, the second end of the above-mentioned stimulation electrode includes a plurality of end faces; a plurality of electrode contacts are provided on each end face; when the second end of the stimulation electrode is connected to the stimulator, the electrode contacts can contact the elastic contact pieces inside the stimulator.

[0062] The second end of the stimulating electrode adopts a multi-end face design, and a plurality of electrode contacts are carefully arranged on each end face. Taking the proximal connection of a common triangular prism-shaped electrode as an example, please refer to Figure 8 , and its three side faces serve as end faces, and six electrode contacts 81 are provided on each side face, which respectively correspond to the six electrode contacts of three independent electrode branches. This layout of multi-end faces and multi-contacts greatly increases the contact area and the number of contact points between the electrode and the stimulator, laying a foundation for the efficient transmission of signals.

[0063] When the second end of the stimulating electrode is connected to the stimulator, the electrode contacts come into contact with the elastic contact pieces inside the stimulator. The elastic contact pieces have excellent elasticity and electrical conductivity. During the insertion process, the electrode contacts apply pressure to the elastic contact pieces, causing them to undergo elastic deformation. This deformation enables the elastic contact pieces to tightly wrap the electrode contacts, forming a stable electrical connection.

[0064] This contact method has many advantages. On the one hand, it effectively reduces the contact resistance, reduces the energy loss during signal transmission, and ensures that the stimulating signal can be transmitted to the nerve tissue with less attenuation. On the other hand, the self-adaptive characteristics of the elastic contact pieces enable them to adapt to a certain insertion error and vibration environment. Even if the electrode position undergoes a slight deviation or is disturbed by external vibration during use, the elastic contact pieces can still maintain a good contact state and maintain stable signal transmission.

[0065] Through the above embodiments, the multi-end face design provides greater flexibility for the installation and use of the stimulating electrode, so that a stable and reliable connection between the electrode and the stimulator can be achieved by using a reasonable structural design and a clever working principle, providing a strong guarantee for the efficient implementation of nerve stimulation therapy.

[0066] In some of these embodiments, a directional pointing mark assembly is further provided at the second end of the above-mentioned stimulating electrode; an insertion direction indication mark assembly is further provided on the outer shell of the stimulator; wherein, when the second end of the stimulating electrode is connected to the stimulator, the directional pointing mark assembly is adapted to the insertion direction indication mark assembly.

[0067] The second end of the stimulating electrode adopts a multi-end face design, and a plurality of electrode contacts are arranged on each end face to increase the contact area with the stimulator and the signal transmission channels. On this basis, a directional pointing mark assembly is specially provided. This assembly is usually presented in a specific shape, color or pattern, such as a raised or recessed arrow shape, and its position and direction are carefully designed to match the layout of the electrode contacts inside the electrode. Exemplarily, please refer to Figure 8, a directional pointing marker assembly 82 with a raised structure is provided outside the second end of the stimulating electrode. In addition, a sealing ring 83 is designed between the electrode contact piece 81 and the directional pointing marker assembly 82 for the sealing treatment of the stimulating electrode and the stimulator.

[0068] The outer shell of the stimulator is correspondingly provided with an insertion direction indication marker assembly. This assembly can be a groove, a protrusion that fits with the directional pointing marker assembly of the stimulating electrode, or a scoring line, a symbol with a specific identifier, etc. When the second end of the stimulating electrode is ready to be connected to the stimulator, the user can quickly and accurately judge the insertion direction of the electrode by observing these two marker assemblies.

[0069] Specifically, when the second end of the stimulating electrode is inserted into the stimulator in the correct direction, the directional pointing marker assembly is adapted to the insertion direction indication marker assembly. During the insertion process, the electrode contact piece gradually contacts and closely fits with the elastic contact piece inside the stimulator. Due to the precise positioning function of the marker assembly, the electrode contact piece can accurately align with the elastic contact piece of the corresponding channel of the stimulator to form a reliable electrical connection.

[0070] More specifically, for the connection structure between the stimulating electrode and the stimulator, please refer to Figure 9A , access holes for respectively connecting two stimulating electrodes are provided on the outer shell of the stimulator, and a strip-shaped insertion direction indication marker assembly 91 is provided on one side of each access hole. In addition, a screw waterproof seal 92 is provided at the top of the outer shell of the stimulator. Further, please refer to Figure 9B , this figure is Figure 9A the internal structure diagram of the stimulating electrode connected to the stimulator in

[0071] Through the above embodiments, through the ingenious cooperation of the directional pointing marker assembly and the insertion direction indication marker assembly, the precise docking of the stimulating electrode and the stimulator is realized, greatly reducing the problem that the connection between the electrode contact point and the stimulator channel is incorrect due to the wrong insertion direction, avoiding the risk of abnormal signal transmission or equipment damage, improving the efficiency and accuracy of electrode insertion, and reducing the operation time and difficulty.

[0072] In some of these embodiments, the above-mentioned stimulation electrodes include a first stimulation electrode and a second stimulation electrode. Among them, the first stimulation electrode and the second stimulation electrode can be respectively provided with three independent electrode branches, each branch has six stimulation sites, and each stimulation site of each independent electrode branch of the stimulation electrode has both stimulation and acquisition functions. These two stimulation electrodes can be respectively connected to three sacral nerve target positions on the left and three sacral nerve target positions on the right. It should be added that this application also supports unilateral sacral nerve multi-electrode access, stimulation and acquisition; please refer to Figure 10 , the three independent electrode branches of the first stimulation electrode are respectively inserted into the three sacral nerve target positions of S2, S3, and S4 on the right side. At this time, the opening of the second stimulation electrode is sealed.

[0073] The multiple independent electrode branches of the first stimulation electrode, and / or the multiple independent electrode branches of the second stimulation electrode are also provided with electrode barbs; wherein, the distance between the position where the electrode barbs are located and the position where the multiple electrode contacts are located is within a preset distance range, and when the independent electrode branch is implanted into the corresponding sacral nerve target position, the distance between the position where the electrode barbs are located and the sacral nerve target position is greater than the distance between the position where each electrode contact is located and the sacral nerve target position. Exemplarily, please refer to Figure 3 , the stimulation electrode is divided into three independent electrode branches 221 in the middle section, which are respectively denoted as branch a, branch b, and branch c. Each branch has six independent electrode contacts, numbered in sequence starting from the position closest to the distal end, which are contacts 0, 1, 2, 3, 4, and 5 in turn. At a certain distance from the electrode contact 222 is the electrode barb 31, which is used for fixing between the stimulation electrode and the sacral foramen.

[0074] This embodiment also provides a parameter configuration method, which is applied to the sacral nerve multi-target collaborative stimulation system described in any of the above embodiments. The process includes the following steps: Obtain stimulation parameters, perform parameter configuration processing based on the stimulation parameters, and provide a stimulation current to at least one independent electrode branch of the stimulation electrode; the stimulation current acts on the sacral nerve target position through the electrode contacts on the independent electrode branch. Among them, the stimulator is used to configure the stimulation and acquisition channels and output stimulation according to the specified stimulation parameters.

[0075] It should be noted that the steps shown in the above process or the flowchart of the drawings can be executed in a computer system such as a set of computer-executable instructions, and although the logical order is shown in the flowchart, in some cases, the steps shown or described can be executed in a different order than here.

[0076] The user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data for analysis, stored data, displayed data, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties.

[0077] Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be completed by instructing relevant hardware through a computer program. The computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above methods. Among them, any reference to a memory, database, or other medium used in the various embodiments provided in this application can include at least one of non-volatile and volatile memories. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetoresistive random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. By way of illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM), etc. The databases involved in the various embodiments provided in this application can include at least one of relational databases and non-relational databases. Non-relational databases can include distributed databases based on blockchain, etc., without limitation. The processors involved in the various embodiments provided in this application can be general-purpose processors, central processors, graphics processors, digital signal processors, programmable logic devices, data processing logics based on quantum computing, etc., without limitation.

[0078] Those skilled in the art should understand that the technical features of the above embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as the scope described in this specification.

[0079] The above-described embodiments merely represent several implementation manners of the present application. The description thereof is relatively specific and detailed, but it should not be construed as a limitation on the scope of the invention patent. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present application, several modifications and improvements can still be made, and these all fall within the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the appended claims.

Claims

1. A sacral nerve multi-target collaborative stimulation system, characterized in that, Comprising: A stimulating electrode and a stimulator; The first end of the stimulating electrode has a plurality of independent electrode branches, and a plurality of electrode contacts are arranged on the outer wall of each independent electrode branch; when each independent electrode branch is implanted into the corresponding sacral nerve target position, the electrode contacts can contact the sacral nerve target position; The stimulator, connected to the second end of the stimulating electrode, is used to provide a stimulating current to each independent electrode branch in the stimulating electrode; the stimulating current acts on the sacral nerve target position through the electrode contacts on the independent electrode branches.

2. The sacral nerve multi-target collaborative stimulation system according to claim 1, characterized in that The multi-target collaborative stimulation system further includes a programmer; The programmer, communicatively connected to the stimulator, is used to transmit the acquired initial stimulation parameters to the stimulator; The stimulator is further used to collect the nerve signal parameters of the sacral nerve target position and generate a signal comparison result according to the nerve signal parameters; The stimulator is further used to adjust the initial stimulation parameters according to the signal comparison result, generate optimized stimulation parameters, and based on the optimized stimulation parameters, provide a new stimulating current to the independent electrode branches.

3. The sacral nerve multi-target synergistic stimulation system according to claim 2, wherein The programmer further includes a display and interaction module; The display and interaction module is used to acquire the input initial stimulation parameters and display the stimulator status information and nerve signal parameters sent by the stimulator received.

4. The sacral nerve multi-target collaborative stimulation system according to claim 1, characterized in that, The second end of the stimulating electrode includes a plurality of end faces; a plurality of electrode tabs are arranged on each end face; when the second end of the stimulating electrode is connected to the stimulator, the electrode tabs can contact the elastic contact tabs inside the stimulator.

5. The sacral nerve multi-target collaborative stimulation system according to claim 4, characterized in that, The second end of the stimulating electrode is further provided with a directional pointing marker assembly; The outer shell of the stimulator is further provided with an insertion direction indication marker assembly; Wherein, when the second end of the stimulating electrode is connected to the stimulator, the directional pointing marker assembly is adapted to the insertion direction indication marker assembly.

6. The sacral nerve multi-target collaborative stimulation system according to claim 1, characterized in that The stimulating electrode includes a first stimulating electrode and a second stimulating electrode; The plurality of independent electrode branches of the first stimulating electrode, and / or the plurality of independent electrode branches of the second stimulating electrode are further provided with electrode barbs; Wherein, the distance between the position where the electrode barbs are located and the position where the plurality of electrode contacts are located is within a preset distance range.

7. The sacral nerve multi-target collaborative stimulation system according to any one of claims 1 to 6, characterized in that The stimulator includes a main control module and a stimulation acquisition module, the stimulation acquisition module includes a control unit, a stimulation unit and a switching unit, and the switching unit includes a first switching subunit; The main control module is used to generate a stimulation instruction indicating at least one first target electrode branch; the first target electrode branch is the branch among the independent electrode branches to which the stimulating current is to be applied; The control unit is used to determine a stimulating electrode contact from the electrode contacts on the first target electrode branch, and in response to the stimulation instruction, control the first switching subunit to connect the stimulation path where the stimulating electrode contact is located; The stimulation unit is used to provide the stimulating current to the first target electrode branch through the stimulation path; the stimulating current acts on the sacral nerve target position through the stimulating electrode contact.

8. The sacral nerve multi-target collaborative stimulation system according to claim 7, wherein, The stimulus acquisition module further includes an acquisition unit, and the switching unit further includes a second switching subunit; The main control module is further configured to generate an acquisition instruction indicating at least one second target electrode branch; the second target electrode branch is a branch for which nerve signal parameters are to be acquired among each of the independent electrode branches; The control unit is configured to determine an acquisition electrode contact from the electrode contacts on the second target electrode branch, and in response to the acquisition instruction, control the second switching subunit to connect the acquisition path where the acquisition electrode contact is located; The acquisition unit is configured to receive the nerve signal parameters of the sacral nerve target site collected by the acquisition electrode contact through the acquisition path.

9. The sacral nerve multi-target collaborative stimulation system according to claim 8, wherein The switching unit further includes a third switching subunit; The third switching subunit is configured to switch the connection state between the stimulation path and the acquisition path.

10. A parameter configuration method, characterized in that, Applied to the sacral nerve multi-target cooperative stimulation system according to any one of claims 1 to 9, the method includes: Obtaining stimulation parameters, performing parameter configuration processing based on the stimulation parameters, and providing a stimulation current to at least one independent electrode branch of the stimulation electrode; the stimulation current acts on the sacral nerve target site through the electrode contacts on the independent electrode branch.

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