Modularized biological fermentation reaction device

Abstract

The invention belongs to the technical field of biological fermentation, and particularly relates to a modular biological fermentation reaction device which comprises a device base, the at least one reaction split chamber is arranged on the upper side of the device base, the reaction split chamber comprises a split main frame, an inner reaction chamber mounted in the split main frame, an inner partition frame, a sealing mesh pad and a split cover plate, the inner partition frame divides the inner reaction chamber into a plurality of independent reaction spaces, and the inner partition frame is arranged in the split main frame; the sealing net pad is arranged on the upper side of the inner separation frame and used for sealing; the invention aims to solve the problems of low reaction efficiency, non-uniform mixing and insufficient flexibility of the existing fermentation device. The split type reaction chamber design is adopted, a traditional large-volume fermentation space is decomposed into a plurality of independent controllable micro-reaction units, fluid dead angles are effectively eliminated, the reaction efficiency is improved, the modular design can flexibly adjust the number of the reaction units according to the fermentation scale, the energy consumption and the yield are in a linear relation, and compared with a traditional device, energy is saved.

Description

Technical Field

[0001] The present invention belongs to the technical field of biological fermentation, and particularly relates to a modular biological fermentation reaction device. Background Art

[0002] A biological fermentation device is equipment used for microbial or cell culture and metabolite production, and is widely applied in fields such as bioengineering, pharmaceuticals, food, agriculture, and environmental protection; biological fermentation technology is widely used in the food industry, pharmaceutical manufacturing, bioenergy, and environmental protection, etc. The efficiency of the fermentation reaction device directly affects the product quality and production cost. Traditional fermentation devices are mostly single large reaction tanks, which have the following defects: Low reaction efficiency: Traditional large stirring reaction tanks require a long time to complete the fermentation reaction, extending the production cycle; Uneven mixing: When the amount of fermentation material is large, it is easy to have the phenomenon of insufficient stirring and poor local reaction effect, affecting the product quality; Lack of flexibility: A single large tank body is difficult to carry out different biological fermentation reactions simultaneously, restricting the feasibility of multitasking; Therefore, it is necessary to design a modular biological fermentation reaction device to solve the above problems. Summary of the Invention

[0003] The purpose of the present invention is to provide a modular biological fermentation reaction device to solve the problems raised in the above background art.

[0004] To achieve the above purpose, the present invention provides the following technical solution: A modular biological fermentation reaction device, comprising: A device base; At least one reaction split chamber, arranged on the upper side of the device base. The reaction split chamber includes a split main frame, an inner reaction chamber installed inside the split main frame, an inner partition frame, a sealing mesh pad, and a split cover plate. The inner partition frame divides the inner reaction chamber into multiple independent reaction spaces, and the sealing mesh pad is arranged on the upper side of the inner partition frame for sealing; A reinforcement mechanism, fixed on the split handle, for fixing the stacked reaction split chambers. The split handle is fixed on the reaction split chamber; A reaction mechanism, arranged inside the inner reaction chamber, including a stirring column rotatably installed inside the inner reaction chamber, a series socket fixed at one end of the stirring column, and a series plug fixed at the other end of the stirring column. The stirring column realizes multi-stage linkage through the series plug and the series socket; A heating system, integrated in the stirring column and the stirring plate, including heating internal wires, heating tubes, and heat conduction lines, for uniformly heating the reaction materials; A drive system, including a stirring motor, a driving worm gear, a driving worm, and a stirring main rod, for driving the rotation of the stirring column.

[0005] Preferably, the reinforcement mechanism includes a main reinforcement frame, a reinforcement hook frame, a compression spring, and a compression plate. The reinforcement hook frame applies a downward pressure to the reaction separation chamber through the compression spring and the compression plate. The length of the main reinforcement frame is adjustable through a splicing plug and a splicing slot. A reinforcement base is provided at the lower end of the main reinforcement frame, and a reinforcement stud is screwed inside the reinforcement base.

[0006] Preferably, the contact surfaces of the series plug and the series socket are provided with a heating series connection groove and a heating series connection head for power and signal transmission. A series card slot is provided inside the series socket. A stirring fixing seat is fixedly installed on the outer side of the stirring column, and the stirring plate is fixedly installed on the stirring fixing seat.

[0007] Preferably, the cross-section of the stirring plate is diamond-shaped, with heat conduction lines on the surface and a heating groove and a reinforcing bracket inside for enhancing the stirring and heat conduction efficiency.

[0008] Preferably, an installation card slot is provided on the upper surface of the inner reaction chamber, and an installation protrusion is provided on the lower side of the sealing mesh pad for quick installation and sealing.

[0009] Preferably, sealing compression protrusions are provided on the lower sides of the split main frame and the split cover plate for enhancing the sealing between the reaction separation chambers.

[0010] Preferably, a power connection brush is provided at the lower end of the stirring main rod and is connected to the heating series connection groove through a heating internal wire to supply power to the heating system.

[0011] Preferably, the drive system transmits the power of the stirring motor to the stirring main rod through a transmission worm gear and a transmission worm to achieve the synchronous rotation of the stirring column. A stirring base is provided at one end of the stirring main rod.

[0012] Preferably, the number of reaction separation chambers can be flexibly adjusted according to the fermentation requirements, and quick connection or separation can be achieved between the reaction separation chambers through series plugs and series sockets.

[0013] Preferably, through the coordinated action of the heating internal wire, the heating tube, and the heat conduction lines, the heating system realizes the uniform heating of the reaction materials and the precise control of the temperature. A heating sleeve seat is installed inside the stirring fixing seat, the heating sleeve seat is arranged outside the heating tube, and the heating internal wire is electrically connected to the heating tube.

[0014] Compared with the prior art, the beneficial effects of the present invention are as follows: 1. Adopting a split reaction chamber design, decomposing the traditional large-volume fermentation space into multiple independent and controllable micro-reaction units, effectively eliminating fluid dead corners, improving the reaction efficiency. The modular design can flexibly adjust the number of reaction units according to the fermentation scale, making the energy consumption and output show a linear relationship, and being more energy-saving than traditional devices.

[0015] 2. Each reaction unit is equipped with an independent stirring and heating system, with high temperature control accuracy and a reduced pH fluctuation range; through the synergistic effect of heat conduction lines and heating tanks, the heat transfer efficiency is improved, avoiding protein denaturation caused by local overheating.

[0016] 3. Through the standardized series plug / socket structure, the expansion or switching of reaction units can be completed within 15 minutes (such as expanding from 10 units of 100L to 30 units of 300L), meeting the requirements of multi-variety and small-batch production; by replacing the sealing mesh pads with different pore sizes, it can be adapted to anaerobic / aerobic fermentation, high-shear / low-shear strains (such as co-cultivation of actinomycetes and yeast), improving the equipment utilization rate. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a schematic structural diagram of the present invention; Figure 2 is a schematic structural diagram of the reaction split chamber of the present invention; Figure 3 is a schematic internal structural diagram of the split main frame of the present invention; Figure 4 is a schematic structural diagram of the stirring column of the present invention; Figure 5 is a schematic structural diagram of the stirring plate of the present invention; Figure 6 is a schematic structural diagram of the stirring column of the present invention; Figure 7 is a schematic structural diagram of the series socket of the present invention; Figure 8 is a schematic internal structural diagram of the device base of the present invention; Figure 9 is a schematic structural diagram of the reinforcement mechanism of the present invention; In the figure: 1, device base; 2, reaction split chamber; 20, split cover plate; 21, split main frame; 22, inner reaction chamber; 23, inner partition frame; 24, sealing mesh pad; 25, split handle; 26, installation slot; 27, installation protrusion; 28, sealing pressing protrusion; 3, reinforcement mechanism; 31, reinforcement main frame; 32, reinforcement base; 33, splicing plug; 34, splicing socket; 35, reinforcement hook frame; 36, compression spring; 37, pressing plate; 38, reinforcement stud; 4, reaction mechanism; 41, stirring column; 411, heating internal wire; 412, heating series connection groove; 413, heating series connection head; 414, series slot; 42, stirring plate; 421, stirring fixing seat; 422, strengthening bracket; 423, heating tank; 424, heating sleeve seat; 425, heating tube; 426, heat conduction line; 43, series plug; 44, series socket; 45, stirring motor; 46, driving worm gear; 47, driving worm; 48, stirring main rod; 481, stirring base; 49, power connection brush. DETAILED DESCRIPTION OF THE INVENTION

[0018] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0019] Embodiment 1: Please refer to Figures 1 to 9 , the present invention provides a technical solution: a modular biological fermentation reaction device, including a device base 1, a reaction split chamber 2 is arranged on the upper side of the device base 1, a reinforcement mechanism 3 is arranged on one side of the reaction split chamber 2, and a reaction mechanism 4 is arranged inside the reaction split chamber 2; the reaction split chamber 2 includes a split main frame 21, an inner reaction chamber 22 is arranged inside the split main frame 21, an inner partition frame 23 is arranged inside the inner reaction chamber 22, a sealing mesh pad 24 is arranged on the upper side of the inner partition frame 23, the reaction mechanism 4 is located inside the inner reaction chamber 22, a split handle 25 is arranged on the outer surface of the reaction split chamber 2, the reinforcement mechanism 3 is installed on the split handle 25, a split cover plate 20 is arranged on the upper side of the reaction split chamber 2, and the corresponding reaction split chamber 2 can be selected according to the needs of biological fermentation. Various materials for fermentation reaction can be added to the space between the inner reaction chamber 22 and the inner partition frame 23, and then the reaction split chambers 2 are stacked together, and the split cover plate 20 is installed on the upper side of the reaction split chamber 2; an installation card slot 26 is arranged on the upper surface of the inner reaction chamber 22, an installation protrusion 27 is arranged on the lower side of the sealing mesh pad 24, and sealing pressing protrusions 28 are arranged on the lower sides of both the split main frame 21 and the split cover plate 20, and series sockets 44 are arranged on the lower sides of both the split main frame 21 and the split cover plate 20. The sealing pressing protrusion 28 presses on the sealing mesh pad 24 to ensure the sealing between each space; an auxiliary connecting pipe can be installed on the split main frame 21 during use and communicated with the inside of the inner reaction chamber 22, and operations such as feeding, observing, or discharging gas can be performed inside the inner reaction chamber 22 as needed during use; the reaction mechanism 4 includes a stirring column 41 rotatably installed inside the inner reaction chamber 22, a series socket 44 fixed to one end of the stirring column 41, and a series plug 43 fixed to the other end of the stirring column 41. Stirring plates 42 are arranged on the outer side of the stirring column 41, and the series plug 43 is engaged in the series socket 44.

[0020] During use, the fermentation reaction space is separated by the reaction separation chamber 2, decomposing the traditional large-volume fermentation space into multiple independent and controllable micro-reaction units, effectively eliminating fluid dead zones, improving reaction efficiency, and can be installed with the corresponding number of reaction separation chambers 2 according to usage needs. During use, the reaction space is reduced, enabling the reaction materials in each space to quickly contact and react with each other, improving fermentation efficiency, and different biological fermentation reactions can be carried out; the modular design can flexibly adjust the number of reaction units according to the fermentation scale, making the energy consumption and output show a linear relationship, and being more energy-efficient than traditional devices.

[0021] Embodiment 2: Please refer to Figures 1 to 9 As shown, on the basis of Embodiment 1, the present invention provides a technical solution: a stirring main rod 48 is rotatably installed inside the device base 1. One end of the stirring main rod 48 is provided with a stirring base 481. Series plugs 43 are provided at one end of both the stirring base 481 and the stirring column 41. A driving worm gear 46 is fixedly installed on the outer side of the stirring main rod 48. A driving worm 47 is engaged with one side of the driving worm gear 46. The driving worm 47 is rotatably installed inside the device base 1. A stirring motor 45 is fixedly installed inside the device base 1. The output shaft of the stirring motor 45 is fixedly connected to one end of the driving worm 47. The driving worm gear 46 and the driving worm 47 drive the stirring motor 45 to drive the stirring main rod 48 to rotate. The stirring main rod 48 drives the stirring column 41 to rotate through the engagement of the series plug 43 and the series card slot 414, thereby driving the stirring plate 42 to rotate and stir; a stirring fixing seat 421 is fixedly installed on the outer side of the stirring column 41, and the stirring plate 42 is fixedly installed on the stirring fixing seat 421.

[0022] Further, please refer to Figures 1 to 9 , a heating internal wire 411 is installed inside the stirring column 41. A heating sleeve seat 424 is installed inside the stirring fixing seat 421. A heating pipe 425 is provided inside the heating sleeve seat 424. The heating internal wire 411 is electrically connected to the heating pipe 425. A heating groove 423 is provided inside the stirring plate 42. A reinforcing bracket 422 is installed inside the heating groove 423. The heating groove 423 communicates with the heating sleeve seat 424. The temperature is sensed by the temperature sensor inside the inner reaction chamber 22 and heated by the heating pipe 425. The heat is guided to the inside of the inner reaction chamber 22 through the heat-conducting medium inside the heating sleeve seat 424 and the heating groove 423; a heating series connection groove 412 is provided inside the series plug 43. A series card slot 414 is provided inside the series socket 44. A heating series connection head 413 is provided inside the series card slot 414. A power connection brush 49 is provided at the lower end of the stirring main rod 48. The power connection brush 49 is connected to the heating series connection groove 412 inside the series plug 43 through the heating internal wire 411. During use, the heating series connection head 413 and the heating series connection groove 412 are plugged in series, facilitating the power connection brush 49 to connect to the power supply to supply power to the heating pipe 425.

[0023] Each reaction unit is equipped with an independent stirring and heating system, with high temperature control accuracy and a reduced pH fluctuation range; through the synergistic effect of the heat conduction lines and the heating tank, the heat transfer efficiency is improved, avoiding protein denaturation caused by local overheating.

[0024] Furthermore, refer to Figures 1 to 9 , the cross-sectional shape of the stirring plate 42 is rhombic, and heat conduction lines 426 are provided on the surface of the stirring plate 42, facilitating stirring and accelerating heat conduction during use; the shapes of the series plug 43 and the series card slot 414 are both hexagonal, and the series connection of the stirring columns 41 is conveniently selected through the engagement of the series plug 43 and the series card slot 414. The shapes of the heating series connection groove 412 and the heating series connection head 413 are circular, facilitating the series heating of the heating tubes 425 during use.

[0025] For the reaction mechanism 4 adopting the above technical solution, during use, the fermentation material in the inner reaction chamber 22 is stirred by the stirring columns 41 and the stirring plate 42. Stirring is carried out for each cavity to ensure more uniform and sufficient reaction. Moreover, during use, the series connection of the series plug 43 and the series socket 44 facilitates the superposition and installation of the reaction split chambers 2 for uniform rotational stirring.

[0026] Furthermore, refer to Figure 1 and Figure 9 , the reinforcement mechanism 3 includes a reinforcement main frame 31. One side of the reinforcement main frame 31 is provided with a reinforcement hook frame 35. A compression spring 36 is arranged inside the reinforcement hook frame 35. One end of the compression spring 36 is provided with a compression plate 37, and the compression plate 37 is slidably installed inside the reinforcement hook frame 35. The lower end of the reinforcement main frame 31 is provided with a reinforcement base 32, and a reinforcement stud 38 is screwed inside the reinforcement base 32; splicing plugs 33 and splicing slots 34 are respectively arranged at both ends of the reinforcement main frame 31. The splicing plug 33 is inserted into the inside of the splicing slot 34 and fixed by bolts. During use, according to the number of reaction split chambers 2 used, the reinforcement main frame 31 of the corresponding length can be combined through the connection of the splicing plug 33 and the splicing slot 34, so that the reinforcement hook frame 35 on the reinforcement main frame 31 can press down and fix each layer of the reaction split chamber 2.

[0027] For the reinforcement mechanism 3 adopting the above technical solution, during use, the reinforcement hook frame 35 on the reinforcement main frame 31 hooks on the split handle 25, and the reinforcement hook frame 35 is pressed down on the split handle 25 and the reaction split chamber 2 through the pressing of the reinforcement stud 38, thereby ensuring that the reaction split chambers 2 are more tightly installed in a stacked manner and making the sealing effect better.

[0028] Through a standardized series plug / socket structure, the expansion or switching of the reaction unit can be completed within 15 minutes (such as expanding from 10 units of 100L to 30 units of 300L), meeting the requirements of multi-variety and small-batch production; by replacing the sealing mesh pads with different pore sizes, it can be adapted to anaerobic / aerobic fermentation, high-shear / low-shear strains (such as co-cultivation of actinomycetes and yeast), improving the equipment utilization rate.

[0029] The working principle and usage process of the present invention: When in use, select the corresponding reaction split chamber 2 according to the needs of biological fermentation. Various materials for the fermentation reaction can be added to the space between the inner reaction chamber 22 and the inner partition frame 23. Then stack the reaction split chambers 2 together, install the split cover plate 20 on the upper side of the reaction split chamber 2, and the sealing and pressing protrusion 28 presses on the sealing mesh pad 24 to ensure the sealing between each space. Hook the reinforcement hook frame 35 on the split handle 25, and by selecting the reinforcement stud 38 to press tightly on the split handle 25 on the device base 1, the pressing plate 37 in the reinforcement hook frame 35 is pulled to press on the split handle 25, and the pressing effect on the split handle 25 and the reaction split chamber 2 is better with the elastic force of the pressing spring 36, thus ensuring the tight connection between the reaction split chambers 2. When the reaction split chambers 2 are stacked, the series plug 43 and the series socket 44 are engaged through the series card slot 414, and are connected in series through the insertion of the heating series connector 413 and the heating series connection slot 412, facilitating the connection of the power supply brush 49 to the power supply to supply power to the heating tube 425. The temperature is sensed by the temperature sensor in the inner reaction chamber 22, heated by the heating tube 425, and at the same time, the heat is guided to the inside of the inner reaction chamber 22 through the heat-conducting medium in the heating sleeve seat 424 and the heating slot 423. The stirring motor 45 drives the stirring main rod 48 to rotate through the transmission of the driving worm gear 46 and the driving worm 47. The stirring main rod 48 drives the stirring column 41 to rotate through the engagement of the series plug 43 and the series card slot 414, thereby driving the stirring plate 42 to rotate and stir, facilitating rapid and sufficient stirring, and thus the biological fermentation reaction efficiency is higher and better.

[0030] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "including a..." does not exclude the existence of additional identical elements in the process, method, article or device including the said element.

[0031] As described above, it is only used to illustrate the technical solution of the present invention rather than to limit it. Any other modifications or equivalent replacements made by those of ordinary skill in the art to the technical solution of the present invention shall be covered within the scope of the claims of the present invention as long as they do not depart from the spirit and scope of the technical solution of the present invention.

Claims

1. A modular biological fermentation reaction device, characterized in that: include: Device base (1); At least one reaction split chamber (2) is arranged on the upper side of the device base (1), the reaction split chamber (2) comprising a split main frame (21), an inner reaction chamber (22) installed inside the split main frame (21), an inner partition frame (23), a sealing mesh pad (24) and a split cover plate (20), wherein the inner partition frame (23) divides the inner reaction chamber (22) into a plurality of independent reaction spaces, and the sealing mesh pad (24) is arranged on the upper side of the inner partition frame (23) for sealing; A reinforcement mechanism (3) is fixed on the split handle (25) and is used to fix the stacked reaction split chambers (2); the split handle (25) is fixed on the reaction split chambers (2); The reaction mechanism (4) is arranged in the inner reaction chamber (22), and comprises a stirring column (41) rotatably mounted inside the inner reaction chamber (22), a series socket (44) fixed at one end of the stirring column (41), and a series plug (43) fixed at the other end of the stirring column (41); the stirring column (41) realizes multi-stage linkage through the series plug (43) and the series socket (44); A heating system, integrated into the stirring column (41) and the stirring plate (42), comprising a heating internal wire (411), a heating tube (425) and a heat-conducting pattern (426); The driving system comprises a stirring motor (45), a driving worm gear (46), a driving worm (47) and a stirring main rod (48), and is used to drive the stirring column (41) to rotate.

2. The modular biological fermentation reaction device according to claim 1, characterized in that: The reinforcement mechanism (3) comprises a reinforcement main frame (31), a reinforcement hook frame (35), a compression spring (36) and a compression plate (37); the reinforcement hook frame (35) applies downward pressure to the reaction chamber (2) through the compression spring (36) and the compression plate (37); the reinforcement main frame (31) is adjustable in length through a splicing plug (33) and a splicing slot (34); a reinforcement base (32) is provided at the lower end of the reinforcement main frame (31); a reinforcement stud (38) is screwed into the inner side of the reinforcement base (32).

3. The modular biological fermentation reaction device according to claim 1, characterized in that: A heating series connection groove (412) and a heating series connection head (413) are provided on the contact surfaces of the series plug (43) and the series socket (44) for power and signal transmission. A series card slot (414) is provided on the inner side of the series socket (44). A stirring fixed seat (421) is fixedly mounted on the outer side of the stirring column (41). The stirring plate (42) is fixedly mounted on the stirring fixed seat (421).

4. The modular biological fermentation reaction device according to claim 1, characterized in that: The stirring plate (42) has a diamond-shaped cross section, is provided with heat-conducting patterns (426) on its surface, and is provided with heating grooves (423) and reinforcing brackets (422) inside, for enhancing stirring and heat-conducting efficiency.

5. The modular biological fermentation reaction device according to claim 1, characterized in that: The upper surface of the inner reaction chamber (22) is provided with a mounting groove (26), and the lower side of the sealing mesh pad (24) is provided with a mounting protrusion (27) for rapid installation and sealing.

6. The modular biological fermentation reaction device according to claim 1, characterized in that: The lower sides of the split main frame (21) and the split cover plate (20) are both provided with sealing pressing protrusions (28) for enhancing the sealing performance between the reaction split chambers (2).

7. The modular biological fermentation reaction device according to claim 1, characterized in that: A power brush (49) is provided at the lower end of the stirring main rod (48), which is connected to the heating series connection groove (412) via the heating internal wire (411) to supply power to the heating system.

8. The modular biological fermentation reaction device according to claim 1, characterized in that: The driving system transmits the power of the stirring motor (45) to the stirring main rod (48) through the transmission worm wheel (46) and the transmission worm (47), thereby realizing the synchronous rotation of the stirring column (41). A stirring base (481) is provided at one end of the stirring main rod (48).

9. The modular biological fermentation reaction device according to claim 1, characterized in that: The number of reaction chambers (2) can be flexibly adjusted according to fermentation requirements, and the reaction chambers (2) can be quickly connected or separated through a series plug (43) and a series socket (44).

10. The modular biological fermentation reaction device according to claim 3, characterized in that: The heating system realizes uniform heating of the reaction materials and precise temperature control through the coordinated action of the internal heating wire (411), the heating tube (425) and the heat-conducting pattern (426); a heating sleeve seat (424) is installed on the inner side of the stirring fixed seat (421); the heating sleeve seat (424) is arranged on the outer side of the heating tube (425); and the internal heating wire (411) is electrically connected to the heating tube (425).

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