Section manufacturing auxiliary device for pathological research

Abstract

The invention discloses a pathological research slice making auxiliary device which comprises a base, a transparent bin is fixedly connected to the base, a dehydration cylinder is placed on the base and located in the transparent bin, a sliding rail is fixedly connected to the top in the transparent bin, an inlet and outlet is formed in the front face of the transparent bin, an exhaust fan is fixedly connected to one side of the transparent bin, and a suction fan is fixedly connected to the other side of the transparent bin. A limiting sliding groove is formed in the lower portion of the sliding rail, a limiting sliding block is slidably installed in the limiting sliding groove, an air cylinder is fixedly connected to the lower portion of the limiting sliding block, a cover cap is fixedly connected to the lower end of the air cylinder, a plurality of liquid inlet and outlet through holes are formed in the surface of the cover cap, clamping plates are arranged on the two sides of the cover cap, and a containing base is arranged below the cover cap. A supporting table is fixedly connected to the front face of the base, and a fixing clamping groove is formed in the supporting table. By means of automatic dewatering and soaking, manual dewatering is not needed, manpower is reduced firstly, and meanwhile it is effectively avoided that operators inhale volatilized dewatering agents, and the physical health of the operators is damaged.

Description

Technical Field

[0001] The present invention relates to an auxiliary device for making sections, and particularly to an auxiliary device for making sections for pathological research. Background Art

[0002] When making pathological sections, the tissue to be examined is first cut into tissue blocks of 2x2x0.5 cm, placed in an embedding cassette, and after a series of dehydration procedures with inorganic chemical reagents such as formalin, gradient alcohol, and xylene, the tissue is made into a tissue wax block using the paraffin embedding method. Then, a paraffin microtome is used to make the tissue block into tissue sections of 3-5 microns, which are adhered to glass slides. By staining with hematoxylin and eosin, the cell nuclei in the tissue are stained blue and the cytoplasm is stained red, facilitating the examiner to observe the cell morphology, nuclear mitotic figures, infiltration conditions, etc. under a microscope, making a pathological diagnosis, and providing assistance for clinical diagnosis and treatment. The production of tissue pathological sections includes the following steps: material collection, fixation, dehydration and clearing, wax infiltration, embedding, sectioning, mounting, staining, and coverslipping.

[0003] Currently, when dehydrating and clearing tumor tissue specimens, when using harmful clearing agents such as xylene for clearing operations, since harmful gases often emanate from harmful clearing agents such as xylene, it seriously threatens the physical health of operators and poses a safety hazard to the physical health of operators. Summary of the Invention

[0004] The purpose of the present invention is to provide an auxiliary device for making sections for pathological research to solve the existing problems mentioned in the above background art.

[0005] To achieve the above purpose, the present invention provides the following technical solution: An auxiliary device for making sections for pathological research, including a base, a transparent chamber fixedly connected to the upper surface of the base, a dehydration cylinder placed on the upper surface of the base, the dehydration cylinder being located inside the transparent chamber, a slide rail fixedly connected to the inner top of the transparent chamber, an inlet and outlet opened on the front surface of the transparent chamber, an exhaust fan fixedly connected to one side of the transparent chamber, a limit chute opened below the slide rail, a limit slider slidably installed in the limit chute, a cylinder fixedly connected to the lower surface of the limit slider, a cover fixedly connected to the lower end of the cylinder, a plurality of liquid inlet and outlet through holes opened on the surface of the cover, clamping plates arranged on both sides of the cover, and a placement base arranged below the cover.

[0006] Preferably, a support table is fixedly connected to the front surface of the base, and a fixed card slot is opened on the upper surface of the support table.

[0007] Preferably, a clamping block is fixedly connected to the lower surface of the placement base, the clamping block cooperating with the fixed card slot, a plurality of drain through holes being opened at a position near the edge inside the placement base, and clamping card slots being opened on both sides of the placement base.

[0008] Preferably, a maintenance opening is provided on the other side of the transparent bin, and a sealing door is rotatably installed in the maintenance opening.

[0009] Preferably, a connecting flange is fixedly connected to the other side of the exhaust fan. An exhaust fan motor is fixedly connected inside the exhaust fan through a bracket, and an exhaust fan blade is fixedly connected to the output end of the exhaust fan motor.

[0010] Preferably, an adjusting screw rod is rotatably installed in the limit sliding groove, and a driving motor is fixedly connected to the back of the transparent bin. The output end of the driving motor is fixedly connected to the adjusting screw rod.

[0011] Preferably, a threaded through hole is provided in the limit slider, and the threaded through hole is in threaded cooperation with the adjusting screw rod.

[0012] Preferably, two groups of hinge ears are symmetrically and fixedly connected to the upper surface of the cover. A hinge seat is fixedly connected to one side of the clamping plate. A connecting shaft is fixedly connected inside the hinge seat, and the connecting shaft is in rotational cooperation with the hinge ear.

[0013] Preferably, a torsion spring is sleeved on the connecting shaft. One end of the torsion spring is fixedly connected to the hinge seat, and the other end of the torsion spring is fixedly connected to the hinge ear.

[0014] Preferably, a triangular clamping block is fixedly connected to a position near the lower edge of one side of the clamping plate, and the triangular clamping block is matched with the clamping slot.

[0015] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0016] 1. Through automated dehydration and soaking, manual dehydration is not required. Firstly, labor is reduced, and secondly, it effectively avoids operators inhaling volatile dehydration agents and damaging the health of operators.

[0017] 2. Starting the exhaust fan motor can drive the exhaust fan blade to rotate. The rotation of the exhaust fan blade can suck the air inside the transparent bin to the connecting flange. The connecting flange is used to connect the waste gas treatment equipment to harmlessly treat the sucked harmful gases.

[0018] 3. The fixed clamping slot and the clamping block cooperate with each other to position the placement base placed on the support table, align the cover with the placement base, and avoid operators spending a long time aligning the position of the placement base. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 is a schematic diagram of the overall structure of the present invention;

[0020] Figure 2 is a schematic diagram of the overall structure of the present invention in the state where the sealing door is opened;

[0021] Figure 3 is a cross-sectional view of the present invention;

[0022] Figure 4 Schematic diagram of the cover structure of the present invention;

[0023] Figure 5 Schematic diagram of the placement base structure of the present invention.

[0024] In the figure: 1. Base; 101. Support platform; 102. Fixed card slot; 103. Dehydration cylinder; 2. Transparent chamber; 201. Maintenance opening; 202. Sealed door; 3. Slide rail; 301. Limit chute; 302. Adjusting screw; 303. Driving motor; 4. Exhaust fan; 401. Connecting flange; 402. Exhaust motor; 403. Exhaust blades; 5. Cover; 501. Liquid inlet and outlet through hole; 502. Cylinder; 503. Limit slider; 504. Threaded through hole; 505. Hinge ear; 506. Clamping plate; 507. Hinge seat; 508. Connecting shaft; 509. Torsion spring; 510. Triangular clamping block; 6. Placement base; 601. Liquid discharge through hole; 602. Clamping block; 603. Clamping card slot. Detailed implementation manners

[0025] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0026] As Figures 1-5 shown, the present invention has the following specific embodiments.

[0027] Embodiment 1

[0028] An auxiliary device for making pathological research sections includes a base 1, a transparent chamber 2 fixedly connected to the upper surface of the base 1, a dehydration cylinder 103 placed on the upper surface of the base 1, the dehydration cylinder 103 being located inside the transparent chamber 2, a slide rail 3 fixedly connected to the inner top of the transparent chamber 2, an inlet and outlet opened on the front surface of the transparent chamber 2, an exhaust fan 4 fixedly connected to one side of the transparent chamber 2, a limit chute 301 opened below the slide rail 3, a limit slider 503 slidably installed in the limit chute 301, a cylinder 502 fixedly connected to the lower surface of the limit slider 503, a cover 5 fixedly connected to the lower end of the cylinder 502, a plurality of liquid inlet and outlet through holes 501 opened on the surface of the cover 5, clamping plates 506 arranged on both sides of the cover 5, and a placement base 6 arranged below the cover 5.

[0029] In this implementation, a dehydration agent is added into the interior of the dehydration cylinder 103. The tissue specimen to be dehydrated is placed on the placement base 6. The cylinder 502 can be used to drive the cover 5 to move down and cover the placement base 6. The clamping plate 506 clamps both sides of the placement base 6 to fix the placement base 6 under the cover 5. Subsequently, the cylinder 502 drives the cover 5 and the placement base 6 to move upward and reset. The limit slider 503 is slidably installed inside the limit chute 301, and then the cover 5 is slidably installed under the slide rail 3. The limit slider 503 is controlled to move into the interior of the transparent chamber 2. The limit slider 503 can drive the cover 5 and the placement base 6 to move into the interior of the transparent chamber 2 through the cylinder 502 and be located above the dehydration cylinder 103. The cylinder 502 is started again to drive the cover 5 and the placement base 6 to move down into the interior of the dehydration cylinder 103, so that the tissue specimen can be immersed in the dehydration agent to perform dehydration treatment on the tissue specimen. The transparent chamber 2 covers the periphery of the dehydration cylinder 103. The agent inside the dehydration cylinder 103 volatilizes and spreads inside the transparent chamber 2. An air extraction mechanism is arranged inside the air extractor 4. The air extraction structure can be used to exhaust the air inside the transparent chamber 2 to the filtration system to prevent the operator from inhaling the volatilized agent components and affecting the health of the experimental personnel.

[0030] Example 2

[0031] A support platform 101 is fixedly connected to the front surface of the base 1. A fixed card slot 102 is provided on the support platform 101. A clamping block 602 is fixedly connected to the lower surface of the placement base 6. The clamping block 602 cooperates with the fixed card slot 102. A plurality of liquid drainage through holes 601 are provided near the edge inside the placement base 6. Clamping card slots 603 are provided on both sides of the placement base 6. An inspection opening 201 is provided on the other side of the transparent chamber 2. A sealing door 202 is rotatably installed in the inspection opening 201. A connection flange 401 is fixedly connected to the other side of the air extractor 4. An air extraction motor 402 is fixedly connected to the air extractor 4 through a bracket. The output end of the air extraction motor 402 is fixedly connected to an air extraction blade 403. An adjusting screw 302 is rotatably installed in the limit chute 301. A driving motor 303 is fixedly connected to the rear surface of the transparent chamber 2. The output end of the driving motor 303 is fixedly connected to the adjusting screw 302. A threaded through hole 504 is provided inside the limit slider 503. The threaded through hole 504 is in threaded cooperation with the adjusting screw 302.

[0032] In this implementation solution, through the mutual cooperation of the fixed card slot 102 and the card block 602, the placement base 6 placed on the platform 101 can be positioned, so that the cover 5 is aligned with the placement base 6. After the device enters the inside of the dehydration cylinder 103, the liquid discharge through hole 601 and the liquid inlet and outlet through hole 501 can enable the liquid medicine to enter the inside. At the same time, after the device is removed, the liquid medicine can be discharged. Starting the driving motor 303 can drive the adjusting screw 302 to rotate. The adjusting screw 302 is in threaded cooperation with the threaded through hole 504. Furthermore, when the adjusting screw 302 rotates, it can drive the limit slider 503 to move. The cover 5 and the placement base 6 are controlled by the cylinder 502 to enter and exit the inside of the transparent chamber 2. The maintenance port 201 facilitates the operator to add the dehydration liquid medicine, and the sealing door 202 can seal the maintenance port 201. Starting the exhaust fan motor 402 can drive the exhaust fan blade 403 to rotate. The rotation of the exhaust fan blade 403 can suck the air inside the transparent chamber 2 to the connecting flange 401. The connecting flange 401 is used to connect the waste gas treatment equipment to harmlessly treat the sucked harmful gas.

[0033] Embodiment 3

[0034] Two groups of hinge ears 505 are symmetrically and fixedly connected to the upper surface of the cover 5. One side of the clamping plate 506 is fixedly connected with a hinge seat 507. A connecting shaft 508 is fixedly connected inside the hinge seat 507. The connecting shaft 508 is rotationally matched with the hinge ear 505. A torsion spring 509 is sleeved on the connecting shaft 508. One end of the torsion spring 509 is fixedly connected with the hinge seat 507, and the other end of the torsion spring 509 is fixedly connected with the hinge ear 505. One side of the clamping plate 506 is fixedly connected with a triangular clamping block 510 near the lower edge position. The triangular clamping block 510 is mutually matched with the clamping card slot 603.

[0035] In this implementation solution, through the rotational cooperation of the connecting shaft 508 and the hinge ear 505, the hinge seat 507 is rotationally installed between the hinge ears 505. The torsion spring 509 can apply a certain torque to the hinge seat 507. The hinge seat 507 driven by the torque will drive the clamping plate 506 to be in a vertical state, and the triangular clamping block 510 will be stuck into the inside of the clamping card slot 603 to fix the placement base 6 under the cover 5. The whole triangular clamping block 510 is triangular. During the downward movement of the cover 5, its inclined surface contacts the upper edge of the placement base 6, and further decomposition will cause the clamping plate 506 to open to both sides. When the triangular clamping block 510 moves to the clamping card slot 603, due to the torque of the torsion spring 509, the clamping plate 506 will reset and drive the triangular clamping block 510 to be stuck into the inside of the clamping card slot 603. When it is necessary to release the restriction on the placement base 6, it is necessary to manually pinch the upper ends of the two clamping plates 506, and the lower part of the clamping plate 506 rotates outward, so that the triangular clamping block 510 is removed from the inside of the clamping card slot 603, thereby releasing the restriction on the placement base 6. At this time, the placement base 6 can be removed from under the cover 5 to expose the dehydrated tissue sample.

[0036] Working principle and usage process of the present invention: Open the sealing door 202, pour a certain amount of dehydration agent into the interior of the dehydration cylinder 103 through the maintenance port 201, then close the sealing door 202 to keep the maintenance port 201 sealed. Start the exhaust fan motor 402 to drive the exhaust fan blade 403 to rotate, suck the air inside the transparent chamber 2 to the waste gas treatment equipment. Place the placement base 6 on the support table 101, and make the clamping block 602 snap into the fixed clamping groove 102. Start the cylinder 502 to drive the cover 5 to move down and cover the placement base 6, and use the clamping plate 506 to clamp both sides of the placement base 6 to fix the placement base 6 under the cover 5. Then, use the cylinder 502 to drive the cover 5 and the placement base 6 to move up and reset. Start the driving motor 303 to drive the adjusting screw 302 to rotate. The rotation of the adjusting screw 302 drives the limit slider 503 to move backward. The limit slider 503 drives the cover 5 and the placement base 6 to move into the transparent chamber 2 through the cylinder 502 and be located above the dehydration cylinder 103. Start the cylinder 502 again to drive the cover 5 and the placement base 6 to move down into the dehydration cylinder 103. The liquid medicine will enter the interior through the liquid inlet and outlet through hole 501 and the liquid discharge through hole 601, so that the tissue sample is immersed in the dehydration agent to dehydrate the tissue sample.

[0037] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A device for assisting the preparation of slices for pathological research, comprising a base (1), characterized in that: A transparent warehouse (2) is fixedly connected to the base (1), a dehydration cylinder (103) is placed on the base (1), the dehydration cylinder (103) is located inside the transparent warehouse (2), a slide rail (3) is fixedly connected to the top of the transparent warehouse (2), an inlet and outlet are provided on the front of the transparent warehouse (2), an exhaust fan (4) is fixedly connected to one side of the transparent warehouse (2), a limit slide groove (301) is provided below the slide rail (3), a limit slider (503) is slidably installed in the limit slide groove (301), a cylinder (502) is fixedly connected below the limit slider (503), a cover (5) is fixedly connected to the lower end of the cylinder (502), a plurality of liquid inlet and outlet through holes (501) are provided on the surface of the cover (5), clamping plates (506) are provided on both sides of the cover (5), and a placement base (6) is provided below the cover (5).

2. The device for making slices for pathological research according to claim 1, characterized in that: A support platform (101) is fixedly connected to the front of the base (1), and a fixing slot (102) is provided on the support platform (101).

3. The device for making slices for pathological research according to claim 2, characterized in that: A card block (602) is fixedly connected to the bottom of the placement base (6), and the card block (602) cooperates with the fixed card slot (102). A plurality of liquid discharge holes (601) are provided near the edge of the placement base (6), and clamping card slots (603) are provided on both sides of the placement base (6).

4. The device for making slices for pathological research according to claim 1, characterized in that: An inspection opening (201) is provided on the other side of the transparent chamber (2), and a sealing door (202) is rotatably installed in the inspection opening (201).

5. The device for making slices for pathological research according to claim 1, characterized in that: A connecting flange (401) is fixedly connected to the other side of the exhaust fan (4), an exhaust motor (402) is fixedly connected to the exhaust fan (4) via a bracket, and an exhaust blade (403) is fixedly connected to the output end of the exhaust motor (402).

6. The device for assisting pathological research slice preparation according to claim 1, characterized in that: An adjusting screw (302) is rotatably installed in the limiting sliding groove (301), a driving motor (303) is fixedly connected to the rear of the transparent chamber (2), and an output end of the driving motor (303) is fixedly connected to the adjusting screw (302).

7. The device for assisting pathological research slice preparation according to claim 6, characterized in that: A threaded through hole (504) is provided in the limiting sliding block (503), and the threaded through hole (504) is threadably matched with the adjusting screw rod (302).

8. The device for assisting pathological research slice preparation according to claim 1, characterized in that: Two groups of hinged ears (505) are symmetrically fixed on the cover (5), a hinged seat (507) is fixed on one side of the clamping plate (506), a connecting shaft (508) is fixed inside the hinged seat (507), and the connecting shaft (508) is rotatably matched with the hinged ears (505).

9. The device for assisting pathological research slice preparation according to claim 8, characterized in that: A torsion spring (509) is sleeved on the connecting shaft (508), one end of the torsion spring (509) is fixedly connected to the hinge seat (507), and the other end of the torsion spring (509) is fixedly connected to the hinge ear (505).

10. The device for making slices for pathological research according to claim 3, characterized in that: A triangular clamping block (510) is fixedly connected to one side of the clamping plate (506) near the lower edge, and the triangular clamping block (510) cooperates with the clamping slot (603).

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