A plant composition and its use in soothing and / or sun protection

The plant composition formed by compounding specific plant extracts solves the problems of high chemical irritation and poor sun protection effect in existing soothing products, and achieves excellent soothing, anti-allergic and sun protection enhancement effects in cosmetics.

CN120227306BActive Publication Date: 2025-09-09宝萃生物科技有限公司
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Patent Information

Application Number
CN202510709955.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-05-29
Publication Date
2025-09-09
Estimated Expiration
2045-05-29

AI Technical Summary

Technical Problem

Existing soothing products contain many chemical ingredients and are highly irritating. In addition, the efficacy of different plant extracts varies greatly, making it difficult to achieve excellent soothing, anti-allergic and sun protection effects at the same time.

Method used

Pomelo peel extract, magnolia bark extract and licorice root extract are specifically compounded and a solubilizer is added to form a plant composition, which is used in cosmetics as a synergist for chemical sunscreens.

Benefits of technology

Significantly inhibits hyaluronidase activity, improves the sun protection performance of chemical sunscreens, reduces adverse skin reactions, and achieves excellent soothing, anti-allergic and sun protection synergistic effects.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention provides a plant composition and its application in soothing and / or sun protection. The plant composition of the present invention comprises 20wt% to 40wt% of pomelo peel extract, 0.1wt% to 5wt% of magnolia bark extract, 0.01wt% to 0.04wt% of liquorice root extract, 1wt% to 10wt% of solubilizer, and the balance is a polyol solvent. The plant composition of the present invention can not only significantly inhibit the activity of hyaluronidase and exert excellent soothing and anti-allergic effects, but also significantly improve the sun protection performance of specific chemical sunscreens, and is suitable for use as and / or preparation of synergists for chemical sunscreens. In addition, compared with a composition in which any one of the plant extracts is replaced, the plant composition obtained by compounding the specific three plant extracts of the present invention has significantly better soothing, anti-allergic and sun protection synergistic effects.
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Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetics, and more particularly, relates to a plant composition and its application in soothing and / or sun protection. Background Art

[0002] Skin sensitivity refers to a hyperreactive state of the skin under physiological or pathological conditions, manifesting as subjective symptoms such as burning, stinging, and rashes, with or without objective signs such as erythema, scaling, and telangiectasia. Currently, many factors can cause skin sensitivity, including oxidative stress caused by ultraviolet radiation, excessive loss of skin lipids due to improper use of cleansing products, damage to the skin barrier, and air pollution. Therefore, using soothing products is crucial for skin health.

[0003] There are numerous soothing products on the market, but most contain a high level of chemical ingredients and can be irritating. Therefore, products made from natural, safe, and abundant plant extracts have become a hot topic in soothing product research and development. However, plant compositions derived from blends of different plant extracts exhibit significant differences, resulting in widely varying efficacy. Summary of the Invention

[0004] In response to the deficiencies of the prior art, the present invention aims to provide a botanical composition that compounds three specific plant extracts. The botanical composition can not only significantly inhibit hyaluronidase activity and exert excellent soothing and anti-allergic effects, but also significantly enhance the sunscreen performance of specific chemical sunscreens. The composition is suitable for use as and / or preparation of a synergist for chemical sunscreens.

[0005] The first object of the present invention is to provide a plant composition.

[0006] The second object of the present invention is to provide use of the above-mentioned plant composition in preparing cosmetics.

[0007] The third object of the present invention is to provide the use of the above-mentioned plant composition in the preparation of soothing products.

[0008] The fourth object of the present invention is to provide the use of the above-mentioned plant composition as and / or in preparing a synergist for chemical sunscreen agents.

[0009] The fifth object of the present invention is to provide the use of the above-mentioned plant composition in the preparation of sunscreen products.

[0010] The above-mentioned purpose of the present invention is achieved through the following technical solutions:

[0011] The present invention provides a plant composition comprising 20 wt% to 40 wt% of a pomelo peel extract, 0.1 wt% to 5 wt% of a magnolia bark extract, 0.01 wt% to 0.04 wt% of a liquorice root extract, 1 wt% to 10 wt% of a solubilizer, and the balance being a polyol solvent.

[0012] The botanical composition of the present invention not only significantly inhibits hyaluronidase activity, exerting excellent soothing and anti-allergic effects, but also significantly enhances the sunscreen performance of specific chemical sunscreens, making it suitable for use as and / or in the preparation of synergists for chemical sunscreens. Furthermore, compared to compositions in which any one of the plant extracts is replaced, the botanical composition obtained by compounding the three specific plant extracts of the present invention exhibits significantly superior soothing, anti-allergic, and sunscreen synergistic effects.

[0013] Preferably, the extract of pomelo peel is 25 wt% to 35 wt%, the extract of magnolia officinalis bark is 1 wt% to 4 wt%, the extract of liquorice root is 0.01 wt% to 0.03 wt%, the solubilizer is 3 wt% to 7 wt%, and the balance is a polyol solvent.

[0014] Most preferably, the extract of pomelo peel is 30 wt %, the extract of magnolia officinalis bark is 2.5 wt %, the extract of liquorice root is 0.02 wt %, the solubilizer is 5 wt %, and the balance is a polyol solvent.

[0015] Preferably, the solubilizer is one or more of polyvinyl pyrrolidone, trideceth-9, PEG-40 hydrogenated castor oil, and polysorbate 20.

[0016] Most preferably, the solubilizer is polyvinylpyrrolidone.

[0017] Preferably, the polyol solvent is one or more of butanediol, 1,2-butanediol, 1,3-propylene glycol, 1,2-pentanediol, 1,2-hexanediol, and glycerol.

[0018] Most preferably, the polyol solvent is butanediol.

[0019] Based on this, the present invention also provides a method for preparing a plant composition, specifically: after the solubilizer is evenly dispersed in a polyol solvent, grapefruit peel extract, magnolia bark extract, and licorice root extract are added and mixed, and the solid-liquid separation is performed to obtain the composition.

[0020] Preferably, the uniform dispersion is carried out at 50-60°C.

[0021] Preferably, the mixing is performed at 50-60°C.

[0022] Preferably, the solid-liquid separation is filtration.

[0023] The plant composition of the present invention can significantly inhibit the activity of hyaluronidase, thereby exerting excellent soothing and anti-allergic effects. Therefore, the use of the above-mentioned plant composition in the preparation of cosmetics and in the preparation of soothing products should be within the scope of protection of the present invention.

[0024] The plant composition of the present invention can significantly enhance the sunscreen performance of specific chemical sunscreens, thereby achieving the original sunscreen effect while reducing the amount of chemical sunscreens used, and greatly reducing adverse skin reactions. Therefore, the present invention also provides the use of the above-mentioned plant composition as and / or in the preparation of a synergist for chemical sunscreens, wherein the chemical sunscreens include one or more of cinnamate chemical sunscreens, salicylic acid chemical sunscreens, triazine chemical sunscreens, and imidazole chemical sunscreens.

[0025] Preferably, the cinnamate chemical sunscreen is one or more of ethylhexyl methoxycinnamate, octocrylene, and isoamyl p-methoxycinnamate, such as ethylhexyl methoxycinnamate and octocrylene in a mass ratio of 8-10:2-4.

[0026] Preferably, the salicylic acid chemical sunscreen is one or more of homosalate and ethylhexyl salicylate, such as homosalate and ethylhexyl salicylate in a mass ratio of 9-11:4-6.

[0027] Preferably, the triazine chemical sunscreen is one or more of ethylhexyl triazone, diethylhexyl butyramido triazone, and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0028] Preferably, the imidazole chemical sunscreen is one or more of disodium phenyl dibenzimidazole tetrasulfonate, phenylbenzimidazole sulfonic acid, sodium phenylbenzimidazole sulfonate, potassium phenylbenzimidazole sulfonate and triethanolamine salt, such as disodium phenyl dibenzimidazole tetrasulfonate and phenylbenzimidazole sulfonic acid in a mass ratio of 3 to 5:3 to 5.

[0029] Based on this, the present invention also provides the use of the above-mentioned plant composition in the preparation of sunscreen products, wherein the sunscreen products contain one or more of cinnamate chemical sunscreens, salicylic acid chemical sunscreens, triazine chemical sunscreens, and imidazole chemical sunscreens.

[0030] In addition, the present invention also provides a cosmetic containing the above-mentioned plant composition and a chemical sunscreen in a mass ratio of 0.1-5:4-30, wherein the chemical sunscreen is one or more of a cinnamate chemical sunscreen, a salicylic acid chemical sunscreen, a triazine chemical sunscreen, and an imidazole chemical sunscreen.

[0031] Preferably, the mass ratio of the plant composition to the chemical sunscreen is 3:5-20.

[0032] More preferably, the mass ratio of the plant composition to the chemical sunscreen is 3:5-15.

[0033] Preferably, the cosmetics are one or more of sunscreen lotion, sunscreen cream, sunscreen spray, sunscreen stick, isolation, liquid foundation, and pressed powder.

[0034] Preferably, the content of the plant composition in the cosmetic is 0.1 wt% to 5 wt%.

[0035] As a preferred embodiment, the cosmetic can be a sunscreen product, comprising the following ingredients in the following mass percentages:

[0036] Sunscreen ingredient 15wt%~15wt%, sunscreen ingredient 27.8wt%~8.2wt%, dibutyl adipate 9wt%~11wt%, cetearyl alcohol 1.4wt%~1.6wt%, glyceryl stearate 1.2wt%~1.3wt%, PEG-100 stearate 1.2wt%~1.3wt%, cetyl phosphate potassium 0.3wt%~0.5wt%, xanthan gum 0.15wt%~0.25wt%, glycerin 0.8wt%~1.2wt%, sodium polyacryloyldimethyl taurate 0.3wt%~0.5wt%, plant composition 0.1wt%~5wt%, phenoxyethanol 0.6wt%~0.8wt%, ethylhexylglycerin 0.08wt%~0.12wt%, and the balance is water.

[0037] In addition, the preparation method of the sunscreen product comprises the following steps:

[0038] S1. Heat the sunscreen ingredient 1 until it dissolves and becomes transparent, then mix with dibutyl adipate, cetearyl alcohol, glyceryl stearate, PEG-100 stearate, and potassium cetyl phosphate to obtain an oil phase;

[0039] S2 xanthan gum, glycerin, sunscreen ingredient 2 and sodium polyacryloyldimethyl taurate were mixed to obtain an aqueous phase;

[0040] S3. Pour the oil phase into the water phase while stirring, and homogenize until fully emulsified;

[0041] S4. After cooling, add water, the above-mentioned plant composition, phenoxyethanol, and ethylhexylglycerin, mix well, and then homogenize until the material is uniform.

[0042] Preferably, the sunscreen ingredient 1 in S1 is an oil-soluble chemical sunscreen, such as a cinnamate chemical sunscreen, a salicylic acid chemical sunscreen, or a triazine chemical sunscreen.

[0043] Preferably, the heating temperature in S1 is 75-85°C.

[0044] Preferably, the mixing temperature in S1 is 75-85°C.

[0045] Preferably, the sunscreen ingredient 2 in S2 is a water-soluble chemical sunscreen, such as an imidazole chemical sunscreen.

[0046] Preferably, the mixing temperature in S2 is 75-85°C.

[0047] Preferably, the stirring speed in S3 is 100 to 400 rpm.

[0048] Preferably, after pouring the aqueous phase in S3, stirring is continued for 1 to 3 minutes.

[0049] Preferably, the homogenization speed in S3 is 3000-6000 rpm.

[0050] Preferably, the cooling in S4 is to below 45°C.

[0051] Preferably, the homogenization speed in S4 is 3000-6000 rpm.

[0052] The present invention has the following beneficial effects:

[0053] 1. The botanical composition of the present invention not only significantly inhibits hyaluronidase activity, exerting excellent soothing and anti-allergic effects, but also significantly enhances the sunscreen performance of specific chemical sunscreens, making it suitable for use as and / or in the preparation of synergists for chemical sunscreens. Furthermore, compared to compositions in which any one of the plant extracts is replaced, the botanical composition obtained by combining the three specific plant extracts of the present invention exhibits significantly superior soothing, anti-allergic, and sunscreen synergistic effects.

[0054] 2. The three active ingredients selected from the botanical composition of the present invention are all derived from plants. The raw materials are easily available, safe and non-irritating, and the preparation process of the botanical composition is simple. DETAILED DESCRIPTION

[0055] The present invention is further described below with reference to specific examples, which, however, are not intended to limit the present invention in any way. Unless otherwise specified, the reagents, methods, and equipment used in the present invention are conventional reagents, methods, and equipment in the art.

[0056] Unless otherwise specified, all reagents and materials used in the following examples were commercially available.

[0057] Example 1 A plant composition

[0058] 1. Ingredients

[0059] 30wt% of pomelo peel extract, 2.5wt% of magnolia bark extract, 0.02wt% of liquorice root extract, 5wt% of polyvinyl pyrrolidone, and the balance is butylene glycol.

[0060] 2. Preparation Method

[0061] Polyvinyl pyrrolidone was added to butanediol and stirred at 55°C until completely dissolved. Then, grapefruit peel extract, magnolia bark extract and licorice root extract were added and mixed evenly at 55°C. The obtained transparent liquid was filtered to obtain the plant composition.

[0062] Example 2 A plant composition

[0063] 1. Ingredients

[0064] 25wt% of pomelo peel extract, 4wt% of magnolia bark extract, 0.01wt% of liquorice root extract, 7wt% of polyvinyl pyrrolidone, and the balance is butylene glycol.

[0065] 2. Preparation Method

[0066] Same as Example 1.

[0067] Example 3 A plant composition

[0068] 1. Ingredients

[0069] 35wt% of pomelo peel extract, 1wt% of magnolia bark extract, 0.03wt% of liquorice root extract, 3wt% of polyvinyl pyrrolidone, and the balance is butylene glycol.

[0070] 2. Preparation Method

[0071] Same as Example 1.

[0072] Example 4 A plant composition

[0073] 1. Ingredients

[0074] 20wt% of pomelo peel extract, 5wt% of magnolia bark extract, 0.01wt% of liquorice root extract, 10wt% of polyvinyl pyrrolidone, and the balance is butylene glycol.

[0075] 2. Preparation Method

[0076] Polyvinyl pyrrolidone was added to butanediol and stirred at 60°C until completely dissolved. Then, grapefruit peel extract, magnolia bark extract, and licorice root extract were added and mixed uniformly at 60°C. The resulting transparent liquid was filtered to obtain the plant composition.

[0077] Example 5 A plant composition

[0078] 1. Ingredients

[0079] 40wt% of pomelo peel extract, 0.1wt% of magnolia bark extract, 0.04wt% of liquorice root extract, 1wt% of polyvinyl pyrrolidone, and the balance is butylene glycol.

[0080] 2. Preparation Method

[0081] Polyvinyl pyrrolidone was added to butanediol and stirred at 50°C until completely dissolved. Then, grapefruit peel extract, magnolia bark extract and licorice root extract were added and mixed uniformly at 50°C. The obtained transparent liquid was filtered to obtain the plant composition.

[0082] Comparative Example 1 A plant composition

[0083] 1. Ingredients

[0084] Same as Example 1, except that the pomelo peel extract is replaced with scutellaria root extract, specifically:

[0085] Scutellaria root extract 30wt%, Magnolia officinalis bark extract 2.5wt%, Licorice root extract 0.02wt%, Polyvinylpyrrolidone 5wt%, and the balance is butylene glycol.

[0086] 2. Preparation Method

[0087] Same as Example 1.

[0088] Comparative Example 2 A plant composition

[0089] 1. Ingredients

[0090] Same as Example 1, except that the Magnolia officinalis bark extract is replaced with Polygonum cuspidatum root extract, specifically:

[0091] Pomelo peel extract 30wt%, Polygonum cuspidatum root extract 2.5wt%, Licorice root extract 0.02wt%, Polyvinylpyrrolidone 5wt%, and the balance is butylene glycol.

[0092] 2. Preparation Method

[0093] Same as Example 1.

[0094] Comparative Example 3 A plant composition

[0095] 1. Ingredients

[0096] Same as Example 1, except that the liquorice root extract is replaced with the Sophora japonica flower extract, specifically:

[0097] 30wt% of pomelo peel extract, 2.5wt% of magnolia bark extract, 0.02wt% of sophora japonica flower extract, 5wt% of polyvinyl pyrrolidone, and the balance is butylene glycol.

[0098] 2. Preparation Method

[0099] Same as Example 1.

[0100] Comparative Example 4 A plant composition

[0101] 1. Ingredients

[0102] Same as Example 1, except that the Magnolia officinalis bark extract is replaced with Forsythia suspensa leaf extract, specifically:

[0103] Pomelo peel extract 30wt%, Forsythia suspensa leaf extract 2.5wt%, Licorice root extract 0.02wt%, Polyvinylpyrrolidone 5wt%, and the balance is Butylene glycol.

[0104] 2. Preparation Method

[0105] Same as Example 1.

[0106] Comparative Example 5 A plant composition

[0107] 1. Ingredients

[0108] Same as Example 1, except that polyvinyl pyrrolidone is replaced by butanediol, specifically:

[0109] 30wt% of pomelo peel extract, 2.5wt% of magnolia bark extract, 0.02wt% of liquorice root extract, and the balance is butylene glycol.

[0110] 2. Preparation Method

[0111] Same as Example 1.

[0112] Test Example 1 Stability Test of Plant Composition

[0113] The plant compositions obtained in Examples 1 to 5 and Comparative Examples 1 to 5 were placed in light, 5°C, 25°C, and 45°C environments for 30 days, and the plant compositions were observed for any unstable phenomena such as stratification, discoloration, and precipitation. The results are shown in Table 1.

[0114] Table 1

[0115]

[0116] As can be seen, the plant compositions obtained in Examples 1-5 all exhibited excellent stability in stability tests at light exposure, 5°C, 25°C, and 45°C. However, Comparative Examples 1-5, which varied the types of plant extracts and removed the solubilizer, all exhibited varying degrees of instability, including delamination, darkening, and particle precipitation. This demonstrates that the plant compositions obtained in the present invention, combining the three specific plant extracts and supplementing them with other ingredients such as the solubilizer, exhibit significantly superior stability.

[0117] Test Example 2: Soothing and anti-allergic efficacy test of plant composition

[0118] 1. Experimental Principle

[0119] The soothing and anti-allergic effects of the plant composition were determined using the in vitro hyaluronidase activity inhibition method. Hyaluronidase is a participant in allergic reactions, breaking down hyaluronic acid in the body, turning it into a low-molecular-weight acidic irritant, causing the release of histamine and inducing allergic symptoms in the body. The hyaluronidase activity inhibition test is a typical in vitro evaluation method for soothing and anti-allergic activity. The hyaluronidase activity inhibition rate is used as an indicator to evaluate the soothing and anti-allergic activity of the plant composition. The higher the inhibition rate, the stronger the soothing and anti-allergic activity of the plant composition, which is also the IC value of the plant composition's inhibitory effect on hyaluronidase activity. 50 The lower the value, the stronger its soothing and anti-allergic activity.

[0120] 2. Prepare the solution

[0121] (1) 0.1 mol / L acetic acid buffer solution (pH = 3.6): Measure 1.5 mL of glacial acetic acid, dilute to 250 mL with ultrapure water, and adjust the pH to 3.6 with NaOH;

[0122] (2) Hyaluronidase solution (7900 U / mL): Weigh 0.1300 g of hyaluronidase into a beaker and add 5 mL of acetate buffer solution to dissolve;

[0123] (3) Sodium hyaluronate solution (1.2 mg / mL): Weigh 0.0240 g of sodium hyaluronate into a beaker and add 20 mL of acetic acid buffer solution to dissolve;

[0124] (4) Calcium chloride solution (12.5 mmol / L): Weigh 0.13875 g of calcium chloride, dissolve it in ultrapure water and dilute to 100 mL;

[0125] (5) Sodium hydroxide solution (0.4 mol / L): Weigh 1.6 g of sodium hydroxide, dissolve it in ultrapure water and make up to 100 mL;

[0126] (6) Sodium borate solution (0.2 mol / L): Weigh 4.0244 g of sodium borate, dissolve it in ultrapure water and dilute to 100 mL;

[0127] (7) Hydrochloric acid solution (10 mol / L): Measure 20.8 mL of concentrated hydrochloric acid, add water to a concentration of 10 mol / L, and shake well;

[0128] (8) PDMAB solution: Weigh 4.00 g of p-dimethylaminobenzaldehyde, add 50 mL of 10 mol / L hydrochloric acid solution, and then add 350 mL of glacial acetic acid.

[0129] 3. Determination of IC of the inhibitory effect of the plant composition on hyaluronidase activity 50 value

[0130] The plant compositions obtained in Examples 1 to 5 and Comparative Examples 1 to 4 were respectively taken and their hyaluronidase activity inhibition rates were measured according to the following steps:

[0131] S1. Incubate 50 μL of 7900 U / mL hyaluronidase solution and 50 μL of the plant composition (as the sample group; a negative control group in which the plant composition was replaced with a solution of polyvinyl pyrrolidone and butanediol in a mass ratio of 5:95; a blank group in which the plant composition was replaced with an acetate buffer solution; an experiment in which the hyaluronidase solution in each group was replaced with a sodium hyaluronate solution for zeroing the data) at 37°C for 20 min.

[0132] S2. Add 50 μL of 12.5 mmol / L calcium chloride solution and incubate at 37°C for 20 min.

[0133] S3. Add 250 μL of 1.2 mg / mL sodium hyaluronate solution and incubate at 37°C for 40 min.

[0134] S4. Add 50 μL of 0.4 mol / L sodium hydroxide solution and 100 μL of 0.2 mol / L sodium borate solution. Heat in a boiling water bath at 100°C for 3 min, then cool to 25°C with ice water.

[0135] S5. Add 1.5 mL of PDMAB solution, incubate in a 37°C water bath for 20 min, remove and cool to 25°C, and scan the wavelength in the range of 450-700 nm using a microplate reader to determine the wavelength of maximum absorption. Measure the absorbance at this wavelength and calculate the hyaluronidase activity inhibition rate according to the formula "Hyaluronidase activity inhibition rate / % = [AB] / [A] × 100%" (where A is the absorbance value of the blank group after zero adjustment, and B is the absorbance value of the sample group or negative control group after zero adjustment). Perform probit regression analysis using SPSS software to determine the concentration of the plant composition at which the hyaluronidase activity inhibition rate is 50%, i.e., IC 50 The results are shown in Table 2.

[0136] Table 2

[0137]

[0138] In the table, the “-” in the negative control group is because its hyaluronidase activity inhibition rate is 0 and IC cannot be determined. 50 value.

[0139] It can be seen that the IC 50 values of the plant compositions obtained in Examples 1-5 for inhibiting hyaluronidase activity are significantly lower than those of Comparative Examples 1-4, indicating that the plant composition of the present invention can significantly inhibit hyaluronidase activity, and thus exert excellent soothing and anti-allergic effects. In addition, compared with the composition in which any one of the plant extracts is replaced, the plant composition obtained by compounding three specific plant extracts in the present invention has significantly more excellent soothing and anti-allergic effects.

[0140] IV. Determination of the combination index CI value of the three plant extracts in the plant composition

[0141] According to the results in Table 2, using the Chou-Talalay method, according to "CI = D A / D (X)A + D B / D (X)B + D C / D (X)C [[ID=2,2]]" (the specific plant extracts A, B, and C of Examples 1-5 and Comparative Examples 1-4 are shown in Table 3; D A 、D B and D C are the concentrations of A, B, and C respectively when the inhibition rate of the plant compositions obtained in Examples 1-5 and Comparative Examples 1-4 on hyaluronidase activity is 50%; D (X)A is the concentration of A when the inhibition rate of system a on hyaluronidase activity is 50%, and system a is obtained by mixing A, polyvinylpyrrolidone, and butanediol in a mass ratio of 30:5:65; D (X)B is the concentration of B when the inhibition rate of system b on hyaluronidase activity is 50%, and system b is obtained by mixing B, polyvinylpyrrolidone, and butanediol in a mass ratio of 30:5:65; D (X)C is the concentration of C when the inhibition rate of system c on hyaluronidase activity is 50%, and system c is obtained by mixing C, polyvinylpyrrolidone, and butanediol in a mass ratio of 30:5:65), the combination index CI values of the three plant extracts in the plant compositions obtained in Examples 1-5 and Comparative Examples 1- are calculated, and the results are shown in Table 4. CI < 0.3 indicates strong synergy, 0.3 < CI < 0.7 indicates synergy, 0.7 < CI < 1 indicates slight synergy, CI = 1 indicates addition, and CI > 1 indicates antagonism.

[0142] Table 3

[0143]

[0144] Table 4

[0145]

[0146] It can be seen that the CI values ​​of the three plant extracts in the plant compositions obtained in Examples 1 to 5 are all less than 0.7, indicating that in the plant composition of the present invention, the pomelo peel extract, the magnolia bark extract, and the liquorice root extract play a strong synergistic or synergistic role in soothing and anti-allergic reactions.

[0147] Test Example 3 Synergistic Effect of Plant Composition on Chemical Sunscreen

[0148] 1. Preparation of sunscreen products

[0149] S1. Heat sunscreen ingredient 1 in Group A in an 80°C water bath until dissolved and transparent. Mix thoroughly with the other ingredients in Group A. Then, mix thoroughly with Group B (all ingredients pre-mixed) and Group C at 80°C to obtain an oil phase.

[0150] S2. Mix Group D (all ingredients pre-mixed), Group E sunscreen ingredient 2, and sodium polyacryloyldimethyl taurate (pre-mixed) at 80°C to obtain an aqueous phase.

[0151] S3. While stirring the aqueous phase with a blender at 200 rpm, quickly pour the oil phase into the aqueous phase while stirring at 200 rpm, then stir at 200 rpm for 2 min, and then homogenize at 4000 rpm until completely emulsified;

[0152] S4. When the mixture cools to below 45°C while stirring, add the deionized water from Group E, Groups F, and Group G (all ingredients have been mixed thoroughly beforehand), stir at 200 rpm for 2 minutes, and then homogenize at 4000 rpm until the mixture is uniform.

[0153] The specific ingredients and dosages of groups A to G are shown in Table 5.

[0154] Table 5

[0155]

[0156] Table 6

[0157]

[0158] In the table, system a was obtained by mixing pomelo peel extract, polyvinyl pyrrolidone, and butylene glycol in a mass ratio of 30:5:65; system b was obtained by mixing magnolia officinalis bark extract, polyvinyl pyrrolidone, and butylene glycol in a mass ratio of 2.5:5:92.5; system c was obtained by mixing liquorice root extract, polyvinyl pyrrolidone, and butylene glycol in a mass ratio of 0.02:5:94.98.

[0159] 2. Sunscreen Efficacy Test

[0160] Sunscreen products 1 to 8 and control sunscreen products 1 to 13 were used as test samples, samples in which the sunscreen ingredients in each test sample were replaced with dibutyl adipate were used as sample blanks, samples in which the plant composition in each test sample was replaced with deionized water were used as control samples, and samples in which the sunscreen ingredients in each control sample were replaced with dibutyl adipate were used as control blanks. Their SPF values ​​were measured according to ISO 24443. The SPF values ​​of the test samples were zeroed using the SPF value of the sample blank (1.13), and the zeroed value was recorded as SPF. 受试样品 The SPF value of the control sample is zeroed with the SPF value of the control blank (1.11), and the zeroed value is recorded as SPF 对照样品 According to "SPF value improvement rate (%) = (SPF 受试样品 -SPF 对照样品 ) / SPF 对照样品 × 100%” to calculate the SPF value improvement rate of the test sample in the presence of the plant composition to characterize the sunscreen synergistic effect of the plant composition on chemical sunscreens. The results are shown in Table 7.

[0161] Table 7

[0162]

[0163] As can be seen, sunscreen products 1-8 all showed significant increases in SPF when containing the botanical composition of the present invention and specific chemical sunscreens, demonstrating that the botanical composition of the present invention can significantly enhance the sunscreen performance of specific chemical sunscreens and is suitable for use as and / or in the preparation of synergists for chemical sunscreens. Furthermore, compared to compositions in which any one of the plant extracts is replaced, or the type of chemical sunscreen is replaced, the botanical composition obtained by compounding the three specific plant extracts of the present invention exhibits significantly superior sunscreen synergistic effects.

[0164] The above embodiments are preferred implementation modes of the present invention, but the implementation modes of the present invention are not limited to the above embodiments. Any other changes, modifications, substitutions, combinations, and simplifications that do not deviate from the spirit and principles of the present invention should be considered as equivalent replacement methods and are included in the scope of protection of the present invention.

Claims

1. A plant composition, characterized in that The invention comprises 20 wt% to 40 wt% of pomelo peel extract, 0.1 wt% to 5 wt% of magnolia bark extract, 0.01 wt% to 0.04 wt% of licorice root extract, 1 wt% to 10 wt% of a solubilizer, and the remainder being a polyol solvent; wherein the solubilizer is one or more of polyvinyl pyrrolidone, trideceth-9, PEG-40 hydrogenated castor oil, and polysorbate 20.

2. Use of the plant composition according to claim 1 in the preparation of cosmetics.

3. Use of the plant composition according to claim 1 in preparing a soothing product.

4. Use of the plant composition according to claim 1 in the preparation of a synergist for cinnamate chemical sunscreens, characterized in that: The cinnamate chemical sunscreen is one or more of ethylhexyl methoxycinnamate, octocrylene, and isoamyl p-methoxycinnamate.

5. Use of the plant composition according to claim 1 in the preparation of a synergist for salicylic acid-based chemical sunscreens, characterized in that: The salicylic acid chemical sunscreen is one or both of homosalate and ethylhexyl salicylate.

6. Use of the plant composition according to claim 1 in the preparation of a synergist for triazine chemical sunscreens, characterized in that: The triazine chemical sunscreen is ethylhexyl triazone.

7. Use of the plant composition according to claim 1 in preparing a sunscreen product, characterized in that: The sunscreen product contains one or more of a cinnamate chemical sunscreen, a salicylic acid chemical sunscreen, and a triazine chemical sunscreen; wherein the cinnamate chemical sunscreen is one or more of ethylhexyl methoxycinnamate, octocrylene, and isoamyl p-methoxycinnamate, the salicylic acid chemical sunscreen is one or two of homosalate and ethylhexyl salicylate, and the triazine chemical sunscreen is ethylhexyl triazone.

Citation Information

Patent Citations

  • Natural plant whitening cream and preparation method thereof

    CN105310938A

  • Grapefruit peel composite anti-allergy lotion and preparation method thereof

    CN116942581A