Embryocyte sedimentation rate detection device and method and storage medium

Abstract

The invention relates to the technical field of biomedical treatment, and discloses an erythrocyte sedimentation rate detection device and method and a storage medium, the erythrocyte sedimentation rate detection device comprises a controller, a sample introduction container, an optical detection instrument and a sample container provided with a sample pool communicated with the sample introduction container, the sample container is installed on the optical detection instrument, and the optical detection instrument is connected with the controller. The optical detection instrument comprises an optical measurement assembly and a movable light source assembly, the light source assembly and the optical measurement assembly are arranged on the two opposite sides of the sample cell respectively, the controller is connected with the optical measurement assembly and the light source assembly, and first light source information of light at the first height position is obtained through the optical detection instrument; and moving the optical detection instrument to obtain second light source information of the light at the second height position, and determining a sedimentation rate detection result of the to-be-detected blood according to the first light source information and the second light source information. The blood sedimentation rate detection efficiency is improved, and the accuracy of collected data is improved.

Description

Technical Field

[0001] The present invention relates to the field of biomedical technologies, and in particular, to an erythrocyte sedimentation rate detection device, method, and storage medium. Background Art

[0002] In the medical field, measuring the erythrocyte sedimentation rate is an important detection index. Currently, the commonly used detection system adopts the Westergren method, which is based on the sedimentation principle of red blood cells under the action of gravity. By observing the distance that red blood cells sink, the sedimentation rate of red blood cells in the blood is measured. However, this method has the problems of long measurement time and low detection efficiency. Generally, a blood sample needs to be placed in a glass tube for at least one hour to accurately measure the sedimentation distance of red blood cells. This long waiting time not only increases the complexity of sample processing but also may affect the timeliness and accuracy of clinical treatment effects. Therefore, there is an urgent need for an erythrocyte sedimentation rate detection system to shorten the detection time and improve the detection efficiency and accuracy. Summary of the Invention

[0003] Embodiments of the present invention provide an erythrocyte sedimentation rate detection device, method, and storage medium to improve the detection efficiency and accuracy of the erythrocyte sedimentation rate.

[0004] An erythrocyte sedimentation rate detection device includes a controller, a sample injection container, an optical detection instrument, and a sample container provided with a sample cell communicating with the sample injection container; the sample container is installed on the optical detection instrument, and the optical detection instrument includes an optical measurement component and a movable light source component; the light source component and the optical measurement component are respectively arranged on opposite sides of the sample cell; the controller is connected to the optical measurement component and the light source component;

[0005] The controller is configured to:

[0006] After driving the blood to be detected to enter the sample cell from the sample injection container and filling the sample cell, emit light through the light source component placed at the first height position of the sample cell, and receive first light source information of the light passing through the blood to be detected at the first height position of the sample cell through the optical measurement component;

[0007] Move the light source component to the second height position and emit light, and receive second light source information of the light passing through the blood to be detected at the second height position of the sample cell through the optical measurement component; the second height position is lower than the first height position;

[0008] Determine the detection result of the sedimentation rate of the blood to be detected according to the first light source information and the second light source information.

[0009] An erythrocyte sedimentation rate detection method includes:

[0010] After driving the blood to be detected into the sample cell from the sample injection container and filling the sample cell, light is emitted by a light source assembly placed at a first height position of the sample cell, and first light source information of the light transmitted through the blood to be detected at the first height position in the sample cell is received by the optical measurement assembly;

[0011] The light source assembly is moved to a second height position and emits light, and second light source information of the light transmitted through the blood to be detected at the second height position in the sample cell is received by the optical measurement assembly; the second height position is lower than the first height position;

[0012] A sedimentation rate detection result of the blood to be detected is determined according to the first light source information and the second light source information.

[0013] A computer-readable storage medium stores a computer program, and when the computer program is executed by a processor, the above-mentioned erythrocyte sedimentation rate detection device is implemented.

[0014] In the above-mentioned erythrocyte sedimentation rate detection device, method and storage medium, first, after driving the blood to be detected into the sample cell from the sample injection container and filling the sample cell, light is emitted by a light source assembly placed at a first height position of the sample cell, and first light source information of the light transmitted through the blood to be detected at the first height position in the sample cell is received by the optical measurement assembly. Then, the light source assembly is moved to a second height position and emits light, and second light source information of the light transmitted through the blood to be detected at the second height position in the sample cell is received by the optical measurement assembly. Finally, a sedimentation rate detection result of the blood to be detected is determined according to the first light source information and the second light source information. In the present invention, the movable light source assembly moves between the first height position and the second height position, and cooperates with the optical measurement assembly to detect the blood to be detected. After obtaining the first light source information and the second light source information corresponding to the first height position and the second height position respectively, the sedimentation rate detection result is determined according to the first light source information and the second light source information, which shortens the detection time, improves the efficiency of blood sedimentation rate detection, and also avoids the problem that the distance between multiple fixed light source assemblies is too close and interferes with each other, and improves the accuracy of the collected data. Description of the Drawings

[0015] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments of the present invention will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present invention, and those of ordinary skill in the art can also obtain other drawings without creative efforts based on these drawings.

[0016] Figure 1 It is a schematic structural diagram of an erythrocyte sedimentation rate detection device in an embodiment of the present invention;

[0017] Figure 2 It is a schematic structural diagram of an erythrocyte sedimentation rate detection device in another embodiment of the present invention;

[0018] Figure 3 It is a schematic structural diagram of an erythrocyte sedimentation rate detection device in yet another embodiment of the present invention;

[0019] Figure 4 It is a schematic flowchart of an erythrocyte sedimentation rate detection method in an embodiment of the present invention. Detailed implementation manners

[0020] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0021] In one embodiment, as Figure 1 shown, a device for detecting the erythrocyte sedimentation rate is provided, including a controller (not shown in the figure), a sample injection container (not shown in the figure), an optical detection instrument, and a sample container provided with a sample cell 3 communicating with the sample injection container; the sample container is installed on the optical detection instrument, and the optical detection instrument includes an optical measurement component 2 and a movable light source component 1; the light source component 1 and the optical measurement component 2 are respectively arranged on opposite sides of the sample cell 3; the controller is connected to the optical measurement component 1 and the light source component 1.

[0022] Understandably, the erythrocyte sedimentation rate detection device is a device for detecting the erythrocyte sedimentation rate. The erythrocyte sedimentation rate detection device may further include a sampling pipeline disposed between the sampling container and the sample container to connect the sampling container and the sample pool 3 of the sample container. The sample container is a container for holding the blood to be detected through the sample pool 3. The optical detection instrument may be an instrument for irradiating the blood to be detected in the sample pool 3 of the sample container, detecting the light transmission property of the blood to be detected in the sample pool 3 at a certain height position, and obtaining the light source information. The light source assembly 1 may be a device for emitting a light source, including but not limited to an ultraviolet light, an infrared light, a near-infrared light, or a broadband light source of a combination of several bands. In this embodiment, the light source assembly 1 may employ a single infrared light emitting assembly that moves up and down. The optical measurement assembly 2 may be a device for receiving the light transmitted through the blood to be detected in the sample pool 3 emitted by the light source assembly 1 and outputting the light source information. In this embodiment, the optical measurement assembly 2 may be for receiving the infrared light emitted by the light source assembly 1 and outputting the light source information corresponding to the light intensity of the received infrared light.

[0023] Further, as Figure 4 shown, the controller is configured to perform the following steps S10-S30:

[0024] S10, after driving the blood to be detected to enter the sample pool 3 from the sampling container and filling the sample pool 3, emit light through the light source assembly 1 placed at the first height position A of the sample pool 3, and receive the first light source information of the light passing through the blood to be detected at the first height A position of the sample pool 3 through the optical measurement assembly 2.

[0025] Understandably, the erythrocyte sedimentation rate detection device may further include a driving component, which can be a device for inputting the blood to be detected from the sampling container into the sample cell 3. In this embodiment, the driving component can be a peristaltic pump. The first height position A can be the height position of the sample cell preset according to actual needs. The light source information can be information characterizing parameters associated with light, including but not limited to light intensity, light absorption spectrum, and light interference. In this embodiment, the first light source information includes the light intensity collected at the first height position A and the first collection time corresponding to the light intensity. Since the blood to be measured is not in a static state immediately after entering the sample cell, certain liquid fluctuations will cause deviations between statistical results. Therefore, in another embodiment, the first light source information includes multiple light intensities collected within a preset time at the first height position A, the collection times corresponding to each light intensity one by one, and the sorting data corresponding to each light intensity one by one (that is, the time points corresponding to each light intensity when each light intensity is collected, and each light intensity is sorted in the order of the collection time). Thus, when the fluctuation difference between the light intensities collected at consecutive multiple collection times is less than the preset fluctuation difference, it can be considered that the blood to be detected has stabilized. At this time, it can be determined that the first light source information refers to the last light intensity collected at the first height position A and its corresponding collection time (i.e., the first collection time).

[0026] Specifically, after the driving component drives the blood to be detected to enter the sample cell 3 from the sampling container and fills the sample cell, the light source component 1 placed at the first height position A of the sample cell emits infrared light, and the optical measurement component 2 receives the first light source information of the light passing through the first height position A of the blood to be detected in the sample cell 3, so as to mark the red blood cell information at the first height position A in the blood to be detected at the current time point, providing accurate information for the subsequent detection of the blood sedimentation rate.

[0027] S20, move the light source component 1 to the second height position B and emit light, and the optical measurement component 2 receives the second light source information of the light passing through the second height position B of the blood to be detected in the sample cell 3; the second height position B is different from the first height position A.

[0028] Specifically, the light source assembly 1 is moved downward to the second height position B of the preset sample cell 3 at a preset moving rate and infrared light is emitted. The optical measurement assembly 2 receives the light passing through the second height position B of the blood to be detected in the sample cell 3, and second light source information is obtained. Here, the preset moving rate can be set according to actual needs. Understandably, the preset moving rate needs to be set greater than the preset sedimentation rate, and the preset sedimentation rate is set according to the fastest sedimentation rate in the historical sedimentation data of the blood. That is, the preset moving rate needs to be greater than the preset sedimentation rate to ensure that the moving rate of the light source assembly 1 downward is necessarily faster than the sedimentation rate of the blood to be detected. Thus, when the light source assembly 1 moves to the second height position B and emits light, the blood to be detected has not yet sedimented to the second height position N, thereby improving the rate and accuracy of the subsequent detection of the sedimentation rate of the blood to be detected and avoiding the problem that the data to be measured cannot be obtained due to the slow moving rate of the light source assembly 1 downward.

[0029] In this embodiment, the second light source information includes the light intensity collected at the second height position B and the second collection time corresponding to the light intensity. The second height position B can be preset according to actual needs, and the second height position B is lower than the first height position A (the blood to be detected will inevitably sediment from the first height position A to the second height position B). In this embodiment, the distance between the second height position B and the first height position A is less than the preset distance (the preset distance can be set according to requirements), so that the measurement of the sedimentation rate of the blood to be detected can be completed in a shorter time (the time for the blood to be detected to sediment from the first height position A to the second height position B is shorter), reducing the detection time of the sedimentation rate and also improving the output efficiency of the subsequent blood sedimentation rate detection, avoiding the problem of low detection efficiency caused by a long measurement time. At the same time, in this embodiment, only one movable light source assembly 1 needs to be set, and the light source information at the first height position A and the second height position B can be measured separately by moving the light source assembly 1, avoiding the problem of mutual interference caused by the too-close distance between multiple fixed light source assemblies 1 and improving the accuracy of the collected data.

[0030] S30. Determine the sedimentation rate detection result of the blood to be detected according to the first light source information and the second light source information.

[0031] Specifically, the first light source information and the second light source information are processed by a preset erythrocyte sedimentation rate model to obtain the sedimentation rate detection result of the blood to be detected output by the preset erythrocyte sedimentation rate model. Here, the preset erythrocyte sedimentation rate model can be an erythrocyte sedimentation rate model preset according to actual needs, and the sedimentation rate detection result can be a detection result indicating successful sedimentation rate detection and including the sedimentation rate, or a detection result indicating failed sedimentation rate detection (for example, the data to be measured is not detected at the second height position B).

[0032] In this embodiment, after driving the blood to be detected to enter the sample cell 3 from the sampling container and filling the sample cell, the light source assembly 1 placed at the first height position A of the sample cell 3 emits light, and the first light source information of the light passing through the blood to be detected at the first height position A of the sample cell 3 is received by the optical measurement assembly 2. The light source assembly 1 is moved to the second height position B and emits light, and the second light source information of the light passing through the blood to be detected at the second height position B of the sample cell 3 is received by the optical measurement assembly 2. The sedimentation rate detection result of the blood to be detected is determined according to the first light source information and the second light source information. In the above embodiment of the present invention, by moving the movable light source assembly between the first height position and the second height position and cooperating with the optical measurement assembly to detect the blood to be detected, after obtaining the first light source information and the second light source information corresponding to the first height position and the second height position respectively, the sedimentation rate detection result is determined according to the first light source information and the second light source information, which shortens the detection time, improves the efficiency of blood sedimentation rate detection, and also avoids the problem of mutual interference caused by too close distances between multiple fixed light source assemblies, and improves the accuracy of data collection.

[0033] In another embodiment, as Figure 2 shown, the optical measurement assembly 2 includes a first measurement assembly 21 disposed at the first height position A and a second measurement assembly 22 disposed at the second height position B. In the step S20, the process of receiving, by the optical measurement assembly 2, the first light source information of the light passing through the blood to be detected at the first height position A of the sample cell 3 includes: after receiving, by the first measurement assembly 21, the first light source information of the light passing through the blood to be detected at the first height position A of the sample cell 3, the light source assembly 1 is turned off. It is understandable that the optical measurement assembly 2 includes the first optical measurement assembly 21 disposed at the first height position A.

[0034] Further, in the step S30, that is, moving the light source assembly 1 to the second height position B and emitting light, and receiving the second light source information of the light passing through the blood to be detected in the sample cell 3 at the second height position B by the optical measurement assembly 2, includes: after moving the light source assembly 1 to the second height position B, turning on the light source assembly 1 to emit light, and receiving the second light source information of the light passing through the blood to be detected in the sample cell 3 at the second height B position by the second measurement assembly 22. It can be understood that the optical measurement assembly 2 includes a second optical measurement assembly 22 disposed at the second height position B.

[0035] Specifically, in this embodiment, after receiving the first light source information of the light passing through the blood to be detected in the sample cell at the first height position by the first optical measurement group disposed at the first height position, the light source assembly is turned off. After moving the light source assembly to the second height position, the light source assembly is turned on to emit light, and the second light source information of the light passing through the blood to be detected in the sample cell at the second height position is received by the second measurement assembly disposed at the second height position. In this embodiment, the light source assembly can move up and down, and the optical measurement assembly does not need to move, but includes a first measurement assembly disposed at the first height position and a second measurement assembly disposed at the second height position respectively. In this way, it can be ensured that after the light source assembly moves from the first height position to the second height position, the light source information of the light emitted by the light source assembly corresponding to a specific height position can be quickly and accurately received by the first measurement assembly and the second measurement assembly respectively, which is more helpful for distinguishing the light source information at different height positions, and improves the efficiency and accuracy of the subsequent blood sedimentation rate detection; at the same time, by turning off and turning on the light source assembly, it is ensured that light is emitted only after moving to a new height position, thereby avoiding meaningless light signals or interference during the measurement process, and improving the accuracy and stability of the measurement.

[0036] In one embodiment, as Figure 3 shown, the optical measurement assembly 2 includes a measurement body 23 and a lifting assembly 24 connecting the measurement body 23. In the step S20, the receiving the first light source information of the light passing through the blood to be detected in the sample cell 3 at the first height position A by the optical measurement assembly 2 includes: after receiving the first light source information of the light passing through the blood to be detected in the sample cell 3 at the first height position A by the measurement body 23 placed at the first height position A, turning off the light source assembly 1.

[0037] Further, in the step S30, that is, moving the light source assembly 1 to the second height position B and emitting light, and receiving the second light source information of the light at the second height position B passing through the blood to be detected in the sample cell 3 by the optical measurement assembly 1, includes: after controlling the lifting assembly 24 to move the measurement body 23 to the second height position B and moving the light source assembly 1 to the second height position B, turning on the light source assembly 1 to emit light, and receiving the second light source information of the light at the second height position B passing through the blood to be detected in the sample cell 3 by the measurement body 23 placed at the second height position B. Understandably, the measurement body 23 and the light source assembly 1 can be moved to the second height position B at the same rate simultaneously, so as to ensure the consistency between the light source assembly 1 and the measurement body 23 and ensure the measurement accuracy. However, in some other embodiments, the measurement body 23 can also be moved first and then the light source assembly 1 can be moved, as long as there is necessarily a measurement body 23 opposite the sample cell 3 to receive the light emitted by the light source assembly 1 to measure the light source information in a timely manner when the light source assembly 1 emits light.

[0038] Specifically, in this embodiment, the optical measurement assembly 2 includes a lifting assembly 24 disposed on the optical measurement assembly 2 and connected to the measurement body 23 to control the up and down movement of the measurement body 23. After receiving the first light source information of the light at the first height position passing through the blood to be detected in the sample cell by the measurement body placed at the first height position, the light source assembly is turned off. After controlling the lifting assembly to move the measurement body to the second height position and moving the light source assembly to the second height position, the light source assembly is turned on to emit light, and the second light source information of the light at the second height position passing through the blood to be detected in the sample cell is received by the measurement body placed at the second height position. In this embodiment, the light source assembly can move up and down, and the optical measurement assembly can also move up and down through the lifting assembly. Both the measurement body and the light source assembly can move from the first height position to the second height position. Therefore, the measurement of the light source information at the first height position and the second height position can be realized by a movable light source assembly and an optical measurement assembly, ensuring accurate measurement at each specified height position; at the same time, by turning off and turning on the light source assembly, it is ensured that light is emitted only after the measurement body and the light source assembly both move to the new height position, so as to ensure that the emitted light can necessarily be received by the measurement body, and meaningless light signals or interferences during the measurement process are also avoided, improving the measurement accuracy and stability.

[0039] In one embodiment, as Figure 1 、 Figure 2 and Figure 3 shown, the sedimentation rate detection result includes a first sedimentation rate detection result. The determining the sedimentation rate detection result of the blood to be detected according to the first light source information and the second light source information includes:

[0040] Obtain the first light transmittance value corresponding to the first light source information and the second light transmittance value corresponding to the second light source information. Understandably, the light transmittance value can be a value representing light intensity. When light is transmitted, if there are particles (such as cells) on the light path, it will cause light scattering (the number of photons transmitted through cell suspensions with different concentrations is different). The turbid cell suspension on the light path absorbs or scatters light and reduces the amount of transmitted light. The lower the cell concentration on the light path, the more the amount of transmitted light, the greater the light intensity, and the greater the light transmittance value; the higher the cell concentration on the light path, the less the amount of transmitted light, the smaller the light intensity, and the smaller the light transmittance value.

[0041] When the second light transmittance value is equal to the first light transmittance value, turn off the light source assembly. Understandably, when the second light transmittance value is equal to the first light transmittance value, it can be determined that the blood to be tested originally located at the first height position A has settled to the second height position B at the second collection time. At this time, the light source assembly can be turned off without continuing to collect the next light source information.

[0042] Input the distance between the first height position A and the second height position B, the first collection time of the first light source information, and the second collection time of the second light source information into a preset erythrocyte sedimentation rate model, and obtain the first sedimentation rate detection result of the blood to be tested output by the erythrocyte sedimentation rate model. Understandably, the preset erythrocyte sedimentation rate model includes the following sedimentation rate formula:

[0043]

[0044] Among them, S t represents the sedimentation rate of the blood to be tested; in this embodiment, S t represents the sedimentation rate of the blood to be tested included in the first sedimentation rate detection result; in some embodiments, S t can also represent the sedimentation rate of the blood to be tested included in the second sedimentation rate detection result;

[0045] L represents the sedimentation distance; in the present invention, L is the distance between the first height position and the second height position.

[0046] τ represents the sedimentation time; in this embodiment, the sedimentation time can be the time difference between the second collection time and the first collection time; in some embodiments, the sedimentation time can be the time difference between the third collection time and the first collection time.

[0047] The preset erythrocyte sedimentation rate model can first calculate the difference between the first height position and the second height position to obtain the sedimentation distance L; calculate the difference between the second collection time and the first collection time to obtain the sedimentation time τ; thus, according to the sedimentation rate formula and the sedimentation distance L and sedimentation time τ, the sedimentation rate S of the blood to be tested can be obtainedt , and then according to the above sedimentation rate S t generate the first sedimentation rate detection result of the blood to be detected.

[0048] In this embodiment, the sedimentation rate detection result of the blood to be detected is determined based on the erythrocyte sedimentation rate model, so as to realize the automatic measurement of the erythrocyte sedimentation rate.

[0049] In one embodiment, as Figure 1 , Figure 2 and Figure 3 shown, the sedimentation rate detection result includes the second sedimentation rate detection result. After obtaining the first light transmittance value corresponding to the first light source information and the second light transmittance value corresponding to the second light source information, it further includes:

[0050] When the second light transmittance value is not equal to the first light transmittance value, return to the third light source information that receives the light at the second height position B of the blood to be detected in the sample cell 3 through the measurement body 23 placed at the second height position B, and obtain the third light transmittance value corresponding to the third light source information. It can be understood that when the second light transmittance value is not equal to the first light transmittance value, it means that the blood to be detected at the first height position A has not settled to the second height position B at the second collection time. Therefore, it is necessary to continue to measure the next light source information at the second height B, that is, the third light source information, and then determine the third light transmittance value according to the third light source information; among them, the measurement and determination process of the third light source information and the third light transmittance value can refer to the second light source information and the second light transmittance value, but the collection time (the third collection time) of the third light source information is after the second collection time.

[0051] When the third light transmittance value is equal to the first light transmittance value, turn off the light source assembly. It can be understood that when the third light transmittance value is equal to the first light transmittance value, it can be determined that the blood originally located at the first height position has settled to the second height position at the third collection time. At this time, the light source assembly can be turned off without continuing to collect the next light source information. Similarly, if the third light transmittance value is not equal to the first light transmittance value, it means that the blood to be detected at the first height position has not settled to the second height position at the third collection time. Therefore, it is necessary to continue to measure the next light source information at the second height position and perform subsequent operations with reference to the above embodiments, that is, when the light transmittance value corresponding to the light source information measured at the second height position is always not equal to the first light transmittance value, it is necessary to perform repeated measurements at the second height position until the light transmittance value obtained at the second height position is equal to the first light transmittance value, and then stop measuring the light source information through the optical measurement component at the second height position, and then enter the next step to calculate the sedimentation rate detection result of the blood to be detected through the erythrocyte sedimentation rate model.

[0052] Input the distance between the first height position and the second height position, the first acquisition time of the first light source information, and the third acquisition time of the third light source information into a preset erythrocyte sedimentation rate model, and obtain the second sedimentation rate detection result of the blood to be detected output by the erythrocyte sedimentation rate model. In this embodiment, the above preset erythrocyte sedimentation rate model can first calculate the difference between the first height position and the second height position to obtain the sedimentation distance L; calculate the difference between the third acquisition time and the first acquisition time to obtain the sedimentation time τ; thus, according to the sedimentation rate formula and the sedimentation distance L and sedimentation time τ, the sedimentation rate S of the blood to be detected can be obtained t , and then according to the above sedimentation rate S t generate the second sedimentation rate detection result of the blood to be detected.

[0053] In this embodiment, when the blood to be detected at the first height position has not settled to the second height position at the second acquisition time, the second sedimentation rate detection result of the blood to be detected is determined by continuously measuring the light source information at the second height position, further realizing the automatic measurement of the erythrocyte sedimentation rate.

[0054] In one embodiment, as Figure 2 and Figure 3 shown, the light source assembly includes a light source 11 and a lens 12 disposed between the light source 11 and the sample cell 3. Understandably, the light source 11 can emit infrared light. The lens 12 can be a preset lens according to needs. In this embodiment, the lens can be a concave lens, so as to focus and collect the light emitted by the light source, improve the optical path transmission, reduce the diffusion or scattering of light, ensure that the light is transmitted from the light source assembly to the optical measurement assembly in a more concentrated manner, improve the intensity and accuracy of the received light, reduce the interference in the measurement, and make the measurement result more reliable.

[0055] In one embodiment, as Figure 1 shown, a driving assembly and a sampling control valve for controlling the on-off of the pipeline between the sampling container and the sample cell are provided between the sampling container and the sample cell. Driving the blood to be detected to enter the sample cell from the sampling container and fill the sample cell includes:

[0056] Start the driving assembly according to the preset control parameters to drive the blood to be detected to flow into the sample cell from the sampling container. Understandably, the preset control parameters can be control parameters preset according to needs. In this embodiment, the preset control parameters can be parameters for controlling the blood to be detected to flow into the sample cell at a constant speed, so as to improve the stability of the blood to be detected after entering the sample cell, and further improve the efficiency and accuracy of the subsequent blood sedimentation rate detection.

[0057] Light is emitted by a light source assembly located at a preset filling height position at the top of the sample cell, and detection light source information of the light transmitted through the preset filling height position of the sample cell is received by the optical measurement assembly. Understandably, the preset filling height position can be the highest height in the sample cell set in advance according to the situation. When it is detected according to the detection light source information that the blood to be detected already exists at the preset filling height position, it can be determined that the sample cell is full. The detection light source information can be information characterizing whether the blood to be detected exists and fills the measured position.

[0058] When it is determined according to the detection light source information that the blood to be detected already exists at the preset filling height position of the sample cell, it is confirmed that the sample cell is full.

[0059] The driving assembly is turned off, the injection control valve is controlled to cut off the pipeline between the injection container and the sample cell, and the light source assembly is moved to the first height position. Understandably, the erythrocyte sedimentation rate detection device may further include an injection control valve provided on the injection pipeline for controlling the on-off of the injection pipeline, and the injection control valve is default closed. When the injection control valve is opened, the blood to be detected can flow from the injection container to the sample cell through the injection pipeline. When the injection control valve is closed, the blood to be detected cannot flow from the injection container to the sample cell through the injection pipeline.

[0060] Specifically, the pipeline between the injection container and the sample cell is opened through the injection control valve, the driving assembly is started according to preset control parameters to drive the blood to be detected to flow from the injection container into the sample cell. After it is confirmed by the light source assembly and the optical measurement assembly that the sample cell is full, the driving assembly is turned off, the injection control valve is controlled to cut off the pipeline between the injection container and the sample cell, and the light source assembly is moved to the first height position, which is convenient for emitting light at the first height position in the next step to measure the first light source information. This embodiment realizes precise control of the entry and filling of the blood to be detected into the sample cell, can automatically confirm the filling state of the sample cell, provides a precise and reliable sample for subsequent optical measurement, and also improves the measurement efficiency.

[0061] In one embodiment, as Figure 1 shown, before driving the blood to be detected to enter the sample cell from the injection container and fill the sample cell, it includes:

[0062] Obtain the working environment parameters at the current time point. Understandably, the working environment parameters can be parameters corresponding to the working environment at the current time point. Here, the working environment can include environmental temperature, environmental humidity, signal conditions, and electromagnetic interference information.

[0063] Adjust the parameters of the optical detection instrument according to the working environment parameters. Understandably, the parameter condition can be a process of proofreading the initial measurement value of the optical detection instrument and locking the initial measurement value, so as to ensure the accuracy of subsequent optical measurements.

[0064] In this embodiment, by obtaining the working environment parameters at the current time point and adjusting the parameters of the optical detection instrument according to the working environment parameters, it is ensured that reliable and accurate measurement results can be obtained by the optical detection instrument in different working environments.

[0065] In another embodiment, the erythrocyte sedimentation rate detection device further includes a sample output container, and a sample input pipeline is provided between the sample input container and the sample cell; the driving assembly is arranged on the sample input pipeline, and a sample input control valve for controlling the on-off of the sample input pipeline between the sample input container and the sample cell is provided. A sample output pipeline is also provided between the sample cell and the sample output container, and a sample output control valve for controlling the on-off of the sample output pipeline is further provided on the sample output pipeline. The sample input control valve and the sample output control valve are both default to be closed.

[0066] In this embodiment, the sample input pipeline between the sample input container and the sample cell is opened by the sample input control valve, and the sample output pipeline on the sample cell is opened by the sample output control valve. The driving assembly is started according to the preset control parameters to drive the blood to be detected to sequentially pass through the sample input container, the sample input pipeline, the sample cell, and the sample output pipeline and enter the sample output container. In this way, a continuous flow between the sample input container and the sample output container is realized. In the embodiment of the present invention, since the distance between the first height position and the second height position is less than the preset distance (the preset distance can be set according to requirements), it is possible to complete the measurement of the sedimentation rate of the blood to be detected in a shorter time (the time for the blood to be detected to settle from the first height position to the second height position is shorter), reducing the detection time of the sedimentation rate and also improving the output efficiency of the subsequent blood sedimentation rate detection. Therefore, in this embodiment, since the time for measuring the sedimentation rate is short, for the blood to be detected that continuously passes through the sample cell through the sample input pipeline in a continuous flow manner and needs to measure the sedimentation rate, the erythrocyte sedimentation rate detection device in the present invention requires a shorter time to detect the sedimentation rate. Therefore, and the sample output control valve and the sample input control valve can be automatically controlled. After closing the sample output control valve and the sample input control valve for the above sedimentation rate detection within a short measurement time, the sedimentation rate sample output control valve and the sample input control valve can be quickly controlled to automatically open again, so that the influence on the above continuous flow is extremely small, ensuring that a large number of blood samples to be detected can quickly flow through the sample cell and improving the efficiency of the blood sedimentation rate in the sample cell.

[0067] In one embodiment, as Figure 4 shown, a method for detecting the erythrocyte sedimentation rate is provided, including the following steps S10 - S30.

[0068] S10. After driving the blood to be detected into the sample cell from the sample injection container and filling the sample cell, emit light through a light source assembly placed at a first height position of the sample cell, and receive first light source information of the light passing through the first height position of the blood to be detected in the sample cell through the optical measurement assembly.

[0069] S20. Move the light source assembly to a second height position and emit light, and receive second light source information of the light passing through the second height position of the blood to be detected in the sample cell through the optical measurement assembly; the second height position is lower than the first height position.

[0070] S30. Determine a sedimentation rate detection result of the blood to be detected according to the first light source information and the second light source information.

[0071] For the specific limitations on the erythrocyte sedimentation rate detection method, reference can be made to the limitations on the erythrocyte sedimentation rate detection device in the above text, which will not be elaborated here.

[0072] It should be understood that the magnitudes of the sequence numbers of the steps in the above embodiments do not mean the order of execution. The order of execution of each process should be determined by its function and internal logic, and should not constitute any limitation to the implementation process of the embodiments of the present invention.

[0073] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the erythrocyte sedimentation rate detection method in the above embodiment is implemented.

[0074] Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be completed by instructing relevant hardware through a computer program. This computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above methods. Among them, any reference to a memory, storage, database, or other medium used in the various embodiments provided in the present application can include non-volatile and / or volatile memories. Non-volatile memories can include read-only memory (ROM), programmable ROM (PROM), electrically programmable ROM (EPROM), electrically erasable programmable ROM (EEPROM), or flash memory. Volatile memories can include random access memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in many forms, such as static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double data rate SDRAM (DDR SDRAM), enhanced SDRAM (ESDRAM), synchronous link DRAM (SLDRAM), Rambus direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and Rambus dynamic RAM (RDRAM), etc.

[0075] Those skilled in the art can clearly understand that, for the convenience and simplicity of description, only the above division of each functional unit and module is used as an example. In actual applications, the above functions can be allocated to different functional units and modules according to needs, that is, the internal structure of the device can be divided into different functional units or modules to complete all or part of the functions described above.

[0076] The above embodiments are only used to illustrate the technical solutions of the present invention, not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present invention, and should all be included in the protection scope of the present invention.

Claims

1. An erythrocyte sedimentation rate detection device, characterized in that, It includes a controller, a sampling container, an optical detection instrument, and a sample container provided with a sample cell communicating with the sampling container; the sample container is installed on the optical detection instrument, and the optical detection instrument includes an optical measurement component and a movable light source component; the light source component and the optical measurement component are respectively arranged on opposite sides of the sample cell; the controller is connected to the optical measurement component and the light source component; The controller is used for: After driving the blood to be detected to enter the sample cell from the sampling container and filling the sample cell, emitting light through the light source component placed at the first height position of the sample cell, and receiving first light source information of the light transmitted through the blood to be detected at the first height position of the sample cell by the optical measurement component; Moving the light source component to the second height position and emitting light, and receiving second light source information of the light transmitted through the blood to be detected at the second height position of the sample cell by the optical measurement component; the second height position is lower than the first height position; Determining a sedimentation rate detection result of the blood to be detected according to the first light source information and the second light source information.

2. The erythrocyte sedimentation rate detection device according to claim 1, wherein, The optical measurement component includes a first measurement component arranged at the first height position and a second measurement component arranged at the second height position; The receiving the first light source information of the light transmitted through the blood to be detected at the first height position of the sample cell by the optical measurement component includes: After receiving the first light source information of the light transmitted through the blood to be detected at the first height position of the sample cell by the first measurement component, turning off the light source component; The moving the light source component to the second height position and emitting light, and receiving the second light source information of the light transmitted through the blood to be detected at the second height position of the sample cell by the optical measurement component includes: After moving the light source component to the second height position, turning on the light source component to emit light, and receiving the second light source information of the light transmitted through the blood to be detected at the second height position of the sample cell by the second measurement component.

3. The erythrocyte sedimentation rate detection device according to claim 1, characterized in that, The optical measurement component includes a measurement body and a lifting component connected to the measurement body; The receiving the first light source information of the light transmitted through the blood to be detected at the first height position of the sample cell by the optical measurement component includes: After receiving the first light source information of the light transmitted through the blood to be detected at the first height position of the sample cell by the measurement body placed at the first height position, turning off the light source component; The moving the light source component to the second height position and emitting light, and receiving the second light source information of the light transmitted through the blood to be detected at the second height position of the sample cell by the optical measurement component includes: Controlling the lifting component to move the measurement body to the second height position, and after moving the light source component to the second height position, turning on the light source component to emit light, and receiving the second light source information of the light transmitted through the blood to be detected at the second height position of the sample cell by the measurement body placed at the second height position.

4. The erythrocyte sedimentation rate detection device according to claim 2 or 3, characterized in that, The sedimentation rate detection result includes a first sedimentation rate detection result; Determining the sedimentation rate detection result of the blood to be detected according to the first light source information and the second light source information includes: Obtaining a first light transmittance value corresponding to the first light source information and a second light transmittance value corresponding to the second light source information; When the second light transmittance value is equal to the first light transmittance value, turning off the light source assembly; Inputting the distance between the first height position and the second height position, the first acquisition time of the first light source information, and the second acquisition time of the second light source information into a preset erythrocyte sedimentation rate model, and obtaining a first sedimentation rate detection result of the blood to be detected output by the erythrocyte sedimentation rate model.

5. The erythrocyte sedimentation rate detection device according to claim 4, wherein The sedimentation rate detection result includes a second sedimentation rate detection result; After obtaining the first light transmittance value corresponding to the first light source information and the second light transmittance value corresponding to the second light source information, it further includes: When the second light transmittance value is not equal to the first light transmittance value, returning to the third light source information of the light received by the measurement body placed at the second height position through the blood to be detected in the sample cell at the second height position, and obtaining a third light transmittance value corresponding to the third light source information; When the third light transmittance value is equal to the first light transmittance value, turning off the light source assembly; Inputting the distance between the first height position and the second height position, the first acquisition time of the first light source information, and the third acquisition time of the third light source information into a preset erythrocyte sedimentation rate model, and obtaining a second sedimentation rate detection result of the blood to be detected output by the erythrocyte sedimentation rate model.

6. The erythrocyte sedimentation rate detection device according to claim 1, characterized in that, The light source assembly includes a light source and a lens provided between the light source and the sample cell.

7. The erythrocyte sedimentation rate detection device according to claim 1, characterized in that A driving assembly and a sample injection control valve for controlling the on-off of the pipeline between the sample injection container and the sample cell are provided between the sample injection container and the sample cell; Driving the blood to be detected to enter the sample cell from the sample injection container and filling the sample cell includes: Starting the driving assembly according to preset control parameters to drive the blood to be detected to flow into the sample cell from the sample injection container; Emitting light through a light source assembly at a preset filling height position at the top of the sample cell, and obtaining detection light source information of the light received by the optical measurement assembly through the preset filling height position of the sample cell; When it is determined according to the detection light source information that there is blood to be detected at the preset filling height position of the sample cell, confirming that the sample cell is filled; Turning off the driving assembly, controlling the sample injection control valve to cut off the pipeline between the sample injection container and the sample cell, and moving the light source assembly to the first height position.

8. The erythrocyte sedimentation rate detection device according to claim 1, characterized in that Before driving the blood to be detected to enter the sample cell from the sample injection container and filling the sample cell, it includes: Obtaining the working environment parameters at the current time point; Adjusting the parameters of the optical detection instrument according to the working environment parameters.

9. A method for detecting erythrocyte sedimentation rate, characterized in that, The erythrocyte sedimentation rate detection method is executed by the erythrocyte sedimentation rate detection device according to any one of claims 1 to 8, and the erythrocyte sedimentation rate detection method includes: After driving the blood to be detected to enter the sample cell from the sample injection container and filling the sample cell, light is emitted by a light source assembly placed at a first height position of the sample cell, and first light source information of the light passing through the first height position of the blood to be detected in the sample cell is received by the optical measurement assembly; The light source assembly is moved to a second height position and emits light, and second light source information of the light passing through the second height position of the blood to be detected in the sample cell is received by the optical measurement assembly; the second height position is lower than the first height position; A sedimentation rate detection result of the blood to be detected is determined according to the first light source information and the second light source information.

10. A computer-readable storage medium storing a computer program, characterized in that, When the computer program is executed by a processor, it implements the erythrocyte sedimentation rate detection method according to claim 9.

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