POCT blood cell analyzer

Abstract

The invention discloses a POCT hematology analyzer which is characterized in that a loading seat is horizontally driven by a driving motor, and a pipetting piece is vertically driven by a lifting motor, so that the POCT hematology analyzer can move each pool body of a kit through a horizontal motor; the POCT hematology analyzer is simple in pipetting operation, compact in structure and small in occupied space when being driven by the motor, the instrument cost of the POCT hematology analyzer is reduced, and miniaturization application of the POCT hematology analyzer is facilitated.

Description

Technical Field

[0001] This application relates to the technical field of blood cell analysis, and particularly to a POCT blood cell analyzer. Background Art

[0002] In the field of medical devices, a POCT blood cell analyzer can cooperate with a kit and a reagent card to perform instant detection on a sample to be tested, so as to improve the detection speed and enable users to quickly obtain detection results.

[0003] When the existing POCT blood cell analyzer performs impedance detection, in order to implement various detection processes such as sample injection, liquid transfer, and detection, multiple driving motors are usually required to control different detection processes, resulting in a large volume and high instrument cost of the POCT blood cell analyzer. Summary of the Invention

[0004] In order to solve the technical problem of high cost caused by using multiple driving motors in the prior art, this application provides a POCT blood cell analyzer.

[0005] In order to solve the technical problems existing in the prior art, this application provides a POCT blood cell analyzer, which includes a seat body, a loading and conveying assembly, and a liquid transfer assembly. The loading and conveying assembly is arranged on the seat body and includes a loading seat and a driving motor. The loading seat is used to carry a kit, and the driving motor is used to drive the loading seat to move horizontally; the liquid transfer assembly is arranged on the seat body and includes a lifting motor and a liquid transfer member. The lifting motor is used to drive the liquid transfer member to move vertically; the kit includes a plurality of linearly arranged pool bodies. The driving motor is used to drive the loading seat to move so that the plurality of pool bodies are respectively located below the liquid transfer member, and the liquid transfer member is used to perform liquid transfer operations on the plurality of pool bodies.

[0006] Optionally, the POCT blood cell analyzer further includes an impedance detection assembly. The impedance detection assembly includes an electrode connecting member. The driving motor is used to drive the loading seat to move to a first detection position so that the electrodes on the kit are elastically docked with the electrode connecting member.

[0007] Optionally, the electrode connecting member includes an electrode bushing, a first electrode, and a second electrode. The seat body includes a side plate. The electrode bushing is arranged on the side plate. The first electrode and the second electrode are respectively fixed on the electrode bushing. The loading seat is located at the first detection position, and the first electrode and the second electrode are respectively electrically connected to the electrodes on the kit.

[0008] Optionally, the above-mentioned POCT hematology analyzer further includes an impedance detection component. The above-mentioned drive motor is used to drive the above-mentioned loading seat to move to multiple working positions to load and unload the above-mentioned reagent kit, and to enable the above-mentioned reagent kit to receive the pipetting operation of the above-mentioned pipetting component and the detection operation of the above-mentioned impedance detection component at different above-mentioned working positions.

[0009] Optionally, the above-mentioned working position includes a loading and unloading working position. An activity hatch is movably arranged on the side surface of the above-mentioned seat body. The above-mentioned drive motor is used to drive the above-mentioned loading seat to abut against and open the above-mentioned activity hatch to receive or unload the above-mentioned reagent kit.

[0010] Optionally, the above-mentioned working positions include a first detection position and a pipetting position. The above-mentioned drive motor is used to move the above-mentioned reagent kit to the above-mentioned pipetting position. The above-mentioned pipetting component is used to transfer liquids among multiple above-mentioned cell bodies at the above-mentioned pipetting position to prepare a first test solution. The above-mentioned drive motor is further used to move the above-mentioned reagent kit to the above-mentioned first detection position, so that the above-mentioned impedance detection component performs a counting test on the first test item of the above-mentioned first test solution. The above-mentioned drive motor is further used to move the above-mentioned reagent kit to the above-mentioned pipetting position. The above-mentioned pipetting component is further used to transfer liquids among multiple above-mentioned cell bodies at the above-mentioned pipetting position to prepare a second test solution. The above-mentioned drive motor is further used to move the above-mentioned reagent kit to the above-mentioned first detection position, so that the above-mentioned impedance detection component performs a counting test on the second test item of the above-mentioned second test solution.

[0011] Optionally, the above-mentioned cell body includes a detection cell and a non-detection cell. The above-mentioned impedance detection component is used to test the first test solution in the above-mentioned detection cell. The above-mentioned drive motor is used to move the above-mentioned detection cell under the above-mentioned pipetting component. The above-mentioned pipetting component is used to transfer the remaining first test solution in the above-mentioned detection cell to the above-mentioned non-detection cell and transfer the above-mentioned second test solution to the above-mentioned detection cell, so that the above-mentioned impedance detection component tests the above-mentioned second test solution.

[0012] Optionally, the above-mentioned POCT hematology analyzer further includes a processor. The above-mentioned processor is connected to the above-mentioned drive motor. The above-mentioned processor is used to control the rotation speed and / or rotation time of the above-mentioned drive motor to adjust at least one parameter of the movement time, movement distance, and movement speed of the above-mentioned loading seat, so that the above-mentioned reagent kit is respectively located at multiple above-mentioned working positions.

[0013] Optionally, the above-mentioned working positions include a first working position and a second working position that are adjacent in time sequence. The above-mentioned processor is used to control the above-mentioned drive motor to move the above-mentioned reagent kit to the initial position in response to the above-mentioned reagent kit completing the corresponding operation at the above-mentioned first working position. The above-mentioned processor is further used to control the above-mentioned drive motor to move the above-mentioned reagent kit from the above-mentioned initial position to the above-mentioned second working position.

[0014] Optionally, the above-mentioned POCT blood cell analyzer further includes a fluorescence detection component disposed on the above-mentioned seat body. The above-mentioned loading seat is further used to receive a reagent card. The above-mentioned fluorescence detection component is used to perform fluorescence detection on the above-mentioned reagent card located at the second detection position, and the above-mentioned impedance detection component is used to perform impedance detection on the above-mentioned reagent kit located at the first detection position. Wherein, the above-mentioned processor is used to: control the above-mentioned driving motor to drive the above-mentioned loading seat to move the first number of steps from the above-mentioned initial position to the first detection position; in response to the above-mentioned reagent kit completing impedance detection, control the above-mentioned driving motor to drive the above-mentioned loading seat to move backward the first number of steps and return to the above-mentioned initial position; control the above-mentioned driving motor to drive the above-mentioned loading seat to move the second number of steps to move the above-mentioned loading seat to the second detection position.

[0015] Compared with the prior art, the POCT blood cell analyzer of the present application drives the loading seat horizontally through a driving motor and drives the pipetting component vertically through a lifting motor, so that the POCT blood cell analyzer can move each pool body of the reagent kit through a horizontal motor to be respectively located under the pipetting component for pipetting. The pipetting operation of the POCT blood cell analyzer is simple, the structure is compact, the space occupied during motor driving is small, the instrument cost of the POCT blood cell analyzer is reduced, and it is beneficial to the miniaturized application of the POCT blood cell analyzer. Description of the Drawings

[0016] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required to be used in the embodiments. Obviously, the following described drawings are only some embodiments of the present application. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0017] Figure 1 It is a schematic structural diagram of an embodiment of the POCT blood cell analyzer provided by the present application;

[0018] Figure 2 It is a schematic structural diagram of another embodiment of the POCT blood cell analyzer provided by the present application;

[0019] Figure 3 It is a schematic structural diagram of yet another embodiment of the POCT blood cell analyzer provided by the present application. Detailed Embodiments

[0020] The present application will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be specifically noted that the following embodiments are only used to illustrate the present application, but do not limit the scope of the present application. Similarly, the following embodiments are only partial embodiments of the present application rather than all embodiments. All other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the scope of protection of the present application.

[0021] Reference to "embodiment" herein means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the present application. The phrase appears in various places in the specification and does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein can be combined with other embodiments.

[0022] In the description of the present application, it should be noted that unless otherwise clearly specified and limited, the terms "installed", "set", "connected", and "coupled" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium. For those of ordinary skill in the art, if there are directional indications (such as up, down, left, right, front, back...) involved in the embodiments of the present application, the directional indications are only used to explain the relative positional relationship and movement conditions between components in a specific posture (as shown in the drawings). If the specific posture changes, the directional indications will also change accordingly.

[0023] Please refer to Figure 1 , Figure 1 which is a schematic structural diagram of an embodiment of the POCT blood cell analyzer provided by the present application. As Figure 1 shown, the POCT blood cell analyzer includes a base body 10, a transfer assembly 20, and a pipetting assembly 30.

[0024] The transfer assembly 20 is disposed on the base body 10 and includes a loading base 21 and a driving motor 22. The loading base 21 is used to carry the reagent kit 210, and the driving motor 22 is used to drive the loading base 21 to move horizontally; the pipetting assembly 30 is disposed on the base body 10 and includes a lifting motor 31 and a pipetting member 32. The lifting motor 31 is used to drive the pipetting member 32 to move vertically; the reagent kit 210 includes a plurality of linearly arranged cells 211. The driving motor 22 is used to drive the loading base 21 to move so that the plurality of cells 211 are respectively located below the pipetting member 32, and the pipetting member 32 is used to perform pipetting operations on the plurality of cells 211.

[0025] Specifically, the pool body 211 of the kit 210 includes a first pool body 211 and a second pool body 211. When the loading seat 21 is at the pipetting position, the first pool body 211 of the kit 210 is located below the pipetting member 32 of the pipetting assembly 30. The lifting motor 31 can directly drive the pipetting member 32 to move in the vertical direction and suck liquid from the first pool body 211 through the pipetting member 32. The driving motor 22 is also used to drive the kit 210 to move horizontally and make the second pool body 211 located below the pipetting member 32. The lifting motor 31 continues to drive the pipetting member 32 to move in the vertical direction and add the sucked liquid to the second pool body 211 to complete the pipetting operation.

[0026] The kit 210 includes a plurality of linearly arranged pool bodies 211. The pool bodies 211 include but are not limited to detection pools, reagent pools, sample pools, etc. The sample pool is used to store the blood sample to be detected, the reagent pool is used to store the reagents required for detection, and the detection pool is used to provide a detection site for blood cell analysis. Exemplarily, the driving motor 22 drives the loading seat 21 to move so that the sample pool and the reagent pool are respectively located below the pipetting member 32. The pipetting member 32 is used to mix the reagent and the blood sample to prepare a sample to be detected and add the sample to be detected to the detection pool for detection.

[0027] Among them, the pipetting member 32 of the pipetting assembly 30 performs pipetting operations on the multiple pool bodies 211 of the kit 210 through a disposable pipette tip 214 to avoid cross-contamination during the detection of different samples to be detected. In one embodiment, the POCT blood cell analyzer can store a plurality of pipette tips 214 at a preset position so that the pipetting assembly 30 can obtain the corresponding pipette tip 214 before pipetting each sample to be detected. In another embodiment, the pipette tip 214 can be inserted into the kit 210. After the POCT blood cell analyzer obtains the kit 210, it controls the loading assembly 20 to dock the pipette tip 214 of the kit 210 with the pipetting member 32 so that the pipetting member 32 can perform pipetting operations through the pipette tip 214 after inserting the pipette tip 214.

[0028] In the embodiments of the present application, the POCT blood cell analyzer horizontally drives the loading seat 21 through a driving motor 22 and vertically drives the pipetting member 32 through a lifting motor 31, so that the POCT blood cell analyzer can move each pool body 211 of the kit 210 through a horizontal motor and make them respectively located below the pipetting member 32 for pipetting. The pipetting operation of the POCT blood cell analyzer is simple, the structure is compact, the space occupied during motor driving is small, the instrument cost of the POCT blood cell analyzer is reduced, and it is beneficial to the miniaturized application of the POCT blood cell analyzer.

[0029] In one embodiment, the POCT blood cell analyzer further includes an impedance detection component 40. The impedance detection component 40 includes an electrode connector 41. The driving motor 22 is used to drive the loading seat 21 to move to the first detection position, so that the electrodes on the test kit 210 are elastically docked with the electrode connector 41.

[0030] Specifically, the impedance detection component 40 may include an electrode connector 41 and a CBC analog circuit board card. The CBC analog circuit board card is electrically connected to the electrode connector 41 through a wire. After the pipetting operation is completed, during the impedance detection of the test sample in the test kit 210, the driving motor 22 is used to drive the loading seat 21 to move to the first detection position, so that the electrodes on the test kit 210 are aligned and connected to the electrode connector 41. The electrode connector 41 is used to conduct an external current signal or voltage signal to the test kit 210. The electrodes on the test kit 210 may include a third electrode 212 and a fourth electrode 213. One of the third electrode 212 and the fourth electrode 213 is a negative electrode and the other is a positive electrode. The detection cell of the test kit 210 is located between the third electrode 212 and the fourth electrode 213. The voltage signal or current signal conducted by the electrode connector 41 contacts the test sample in the detection cell through the third electrode 212 and the fourth electrode 213, so that the CBC analog circuit board card can characterize the blood cell characteristics of the test sample by collecting the electrical pulse signal between the third electrode 212 and the fourth electrode 213.

[0031] Among them, the electrode connector 41 is fixedly arranged on the seat body of the POCT blood cell analyzer. The electrode connector 41 does not need to move with the driving motor 22, so that the driving motor 22 can ensure the stability of the electrode connection only by controlling the position of the test kit 210, reducing the complexity of the impedance detection component 40; moreover, the electrode connector 41 needs to be connected to an external power supply, circuit, etc. The fact that the electrode connector 41 does not need to move with the driving motor 22 also facilitates the wiring and cable management of the electrode connector 41, reducing the complexity of assembly. According to the differences in the shape of the test kit 210, actual usage requirements, etc., the electrode connector 41 can be set in the form of a column, a dot or a sheet, etc., so as to flexibly adjust the shape of the test kit 210, the arrangement of the cell body 211, etc. Exemplarily, the electrode connector 41 includes, but is not limited to, components such as electrode pins, electrode contacts, and electrode sheets, and no specific limitation is made here.

[0032] In the embodiment of the present application, the POCT hematology analyzer moves the loading seat 21 to the first detection position through the driving motor 22, and elastically docks the electrodes of the reagent kit 210 on the loading seat 21 with the electrode connecting member 41 of the impedance detection assembly 40, so that the driving motor 22 can be used to assist in pipetting operation and alignment for impedance detection. The structure of the POCT hematology analyzer is compact, and the space occupied during motor driving is small. Moreover, the electrodes on the reagent kit 210 are elastically docked with the electrode connecting member 41 to buffer the impact force generated when the electrodes and the electrode connecting member 41 are docked through the elastic force, thereby improving the service life of the impedance detection assembly 40.

[0033] Optionally, please refer to Figure 2 , Figure 2 which is a schematic structural diagram of another embodiment of the POCT hematology analyzer provided by the present application. As Figure 2 shown, the electrode connecting member 41 includes an electrode bushing 411, a first electrode 412 and a second electrode 413. The seat body 10 includes side plates. The electrode bushing 411 is arranged on the side plates. The first electrode 412 and the second electrode 413 are respectively fixed on the electrode bushing 411. The loading seat 21 is located at the first detection position, and the first electrode 412 and the second electrode 413 are respectively electrically connected to the electrodes on the reagent kit 210.

[0034] Specifically, the side plates of the seat body 10 are used to provide stable support for the impedance detection assembly 40. The electrode bushing 411 is arranged on the side plates. The first electrode 412 and the second electrode 413 are inserted into the electrode bushing 411. The electrode bushing 411 is used to maintain the stability of the first electrode 412 and the second electrode 413, so that the first electrode 412 and the second electrode 413 are maintained at a preset height of the side plates. Wiring holes are provided on the first electrode 412 and the second electrode 413, and the first electrode 412 and the second electrode 413 are connected to an external power supply line through the wiring holes. When the driving motor 22 moves the loading seat 21 to the first detection position, the electrodes of the reagent kit 210 are docked with the first electrode 412 and the second electrode 413, and the first electrode 412 and the second electrode 413 conduct electricity to the detection pool of the reagent kit 210. Among them, one of the first electrode 412 and the second electrode 413 can be a positive electrode, and the other can be a negative electrode.

[0035] Furthermore, elastic members can be sleeved on the first electrode 412 and the second electrode 413. The elastic members are used to play a buffering role to slow down the impact force generated when the driving motor 22 pushes the electrodes of the reagent kit 210 to dock with the first electrode 412 and the second electrode 413, thereby improving the stability and reliability of the electrode connection process. In a possible implementation manner, the elastic member can be an elastic spring arranged around the outside of the first electrode 412 and the second electrode 413, etc.

[0036] In one embodiment, the driving motor 22 is used to drive the loading seat 21 to move to multiple working positions to load and unload the reagent kit 210, and to enable the reagent kit 210 to receive the pipetting operation of the pipetting assembly 30 and the detection operation of the impedance detection assembly 40 at different working positions.

[0037] Specifically, when the driving motor 22 drives the loading seat 21 to move on the seat body 10, the loading seat 21 has multiple working positions on the seat body 10. The driving motor 22 is used to drive the loading seat 21 to stay at or pass through each working position, so that the loading seat 21 can complete the loading of the reagent kit 210, and enable the reagent kit 210 to receive the corresponding operations applied by the components of the POCT blood cell analyzer at different working positions. Among them, the working position may include a pipetting position. Since the reagent kit 210 includes multiple cell bodies 211, the pipetting assembly 30 is used to transfer liquid between the multiple cell bodies 211. The above-mentioned pipetting position is actually the position when the driving motor 22 moves a certain cell body 211 of the reagent kit 210 below the pipetting part 32, and it is not a fixed position. The working position may also include a first detection position. The driving motor 22 is used to move the loading seat 21 to the first detection position so that the impedance detection assembly 40 can perform impedance detection on the reagent kit 210.

[0038] In the embodiment of the present application, the POCT blood cell analyzer uses the horizontal drive of a driving motor 22 to assist the loading seat 21 to complete functions such as loading and unloading the reagent kit 210, assisting the reagent kit 210 to complete the pipetting operation and the detection operation. Compared with the method of using multiple motors to perform corresponding operations, the structure is more compact, which can effectively improve the driving efficiency of the POCT blood cell analyzer, reduce the space occupied during motor driving, and reduce the instrument cost of the POCT blood cell analyzer.

[0039] Optionally, please refer to Figure 3 , Figure 3 which is a schematic structural diagram of another embodiment of the POCT blood cell analyzer provided by the present application. As Figure 3 shown, the working position includes a loading and unloading working position. An active hatch 110 is movably arranged on the side of the seat body 10. The driving motor 22 is used to drive the loading seat 21 to abut against and open the active hatch 110 to receive or unload the reagent kit 210.

[0040] Specifically, the seat body 10 is surrounded by side plates. The movable hatch 110 can be arranged on one of the side surfaces of the side plates, and the movable hatch 110 is movably connected to the side plates. Exemplarily, the movable hatch 110 can be rotatably connected to the side plates through a rotating member, and the driving motor 22 is used to drive the loading seat 21 to abut against the movable hatch 110 so as to rotate and open the movable hatch 110; alternatively, the movable hatch 110 can be opened and closed by a motor or a cylinder, and a touch button can be arranged inside the movable hatch 110, and the driving motor 22 is used to drive the loading seat 21 to abut against the touch button and open the movable hatch 110. After the movable hatch 110 is opened, the driving motor 22 can continue to drive the loading seat 21 to move outward until it reaches the loading and unloading working position, or the driving motor 22 stops working and the loading seat 21 is kept at the current position (the current position is the loading and unloading working position), and the user is used to place the test kit 210 on the loading seat 21 or unload the test kit 210 from the loading seat 21.

[0041] In a possible implementation manner, a rotating shaft is arranged on the side plate, and the movable hatch 110 is rotatably connected to the rotating shaft. The movable hatch 110 can be connected to the seat body 10 through a connecting member such as a torsion spring, so that the movable hatch 110 can be opened and closed rotatably through the rotating shaft, which is convenient for the test kit 210 to push the movable hatch 110.

[0042] In the embodiment of the present application, the driving motor 22 drives the loading seat 21 to open the movable hatch 110 and enables the loading seat 21 to receive or unload the test kit 210 at the loading and unloading working position, so as to improve the utilization efficiency of the driving motor 22, enable the driving motor 22 to be used for assisting multiple detection processes of the POCT blood cell analyzer, and reduce the instrument cost.

[0043] Optionally, the working positions include a first detection position and a liquid transfer position. The driving motor 22 is used to move the test kit 210 to the liquid transfer position, and the liquid transfer assembly 30 is used to transfer liquids among a plurality of pools 211 at the liquid transfer position to prepare a first test solution. The driving motor 22 is further used to move the test kit 210 to the first detection position, so that the impedance detection assembly 40 performs a counting test on the first test solution for a first detection item.

[0044] The driving motor 22 is further used to move the test kit 210 to the liquid transfer position, the liquid transfer member 32 is further used to transfer liquids among a plurality of pools 211 at the liquid transfer position to prepare a second test solution, and the driving motor 22 is further used to move the test kit 210 to the first detection position, so that the impedance detection assembly 40 performs a counting test on the second test solution for a second detection item.

[0045] Specifically, the impedance detection component 40 can be used to perform impedance counting tests on the first test item and / or the second test item of the test kit 210. The working positions include a first detection position and a liquid transfer position. The driving motor 22 is used to move the loading seat 21 to the liquid transfer position, so that the liquid transfer member 32 transfers the liquid in multiple cell bodies 211, prepares a first test solution, and adds the first test solution to the detection cell. The driving motor 22 then continues to move the test kit 210 to the first detection position, so that the electrode connection member 41 of the impedance detection component 40 is docked with the electrode of the test kit 210, and the impedance detection component 40 performs a counting test on the first test solution in the detection cell for the first test item. After completing the test of the first test item, the driving motor 22 continues to move the test kit 210 to the liquid transfer position, so that the liquid transfer member 32 prepares a second test solution and adds the second test solution to the detection cell. The driving motor 22 then continues to move the test kit 210 to the first detection position to perform a counting test on the second test item.

[0046] It can be understood that there are differences in the types, dosages, etc. of the reagents added to the test solutions for different test items. In this embodiment, when using a single driving motor 22 to drive the loading seat 21 to move to each working position, it is necessary to prepare the first test solution and the second test solution separately. In an alternative embodiment, the first test item can be at least one of red blood cell count and platelet count, and the second test item can be at least one of white blood cell count and reticulocyte count.

[0047] In the embodiment of the present application, a single driving motor 22 is used to drive the loading seat 21 to move back and forth between the first detection position and the liquid transfer position to implement the tests of the first test item and the second test item. The detection method is simple, and the detection scenarios of the POCT blood cell analyzer are diverse; the space occupied during motor driving is small, reducing the instrument cost of the POCT blood cell analyzer.

[0048] Further, the cell body 211 includes a detection cell and a non-detection cell. The impedance detection component 40 is used to test the first test solution in the detection cell. The driving motor 22 is used to move the detection cell under the liquid transfer member 32. The liquid transfer assembly 30 is used to transfer the remaining first test solution in the detection cell to the non-detection cell and transfer the second test solution to the detection cell, so that the impedance detection component 40 tests the second test solution.

[0049] Specifically, the detection cell is the cell body 211 used as the detection site, and the non-detection cell can be a reagent cell, a sample cell, a waste liquid cell, etc. on the reagent kit 210. After the impedance detection component 40 completes the first detection item and before testing the second detection item, the driving motor 22 needs to move the detection cell under the pipetting member 32, so as to transfer the remaining first test solution in the detection cell to the non-detection cell through the pipetting member 32, realizing the reuse of the detection cell, and the non-detection cell is used as the storage location for waste liquid. It can be understood that, in one embodiment, the above non-detection cell can be used to store reagents, samples, etc., but the liquid in the non-detection cell does not need to be used anymore after the waste liquid transfer process, so as to improve the utilization rate of the cell body 211; in other embodiments, the above non-detection cell can also be a waste liquid cell specifically used to store waste liquid, and no specific limitation is made here.

[0050] Optionally, the POCT blood cell analyzer further includes a processor, the processor is connected to the driving motor 22, and the processor is used to control the rotation speed and / or rotation time of the driving motor 22, so as to adjust at least one parameter of the movement time, movement distance and movement speed of the loading seat 21, so that the reagent kit 210 is respectively located at multiple working positions.

[0051] In the embodiment of the present application, the driving motor 22 moves the detection cell under the pipetting member 32, and the pipetting assembly 30 is used to transfer the remaining first test solution in the detection cell to the non-detection cell, so that the impedance detection component 40 can continue to test the second test solution through the reagent kit 210, so as to perform multiple item tests through one reagent kit 210, and the detection method is simple and the detection efficiency is high.

[0052] Optionally, the working positions include a first working position and a second working position adjacent in time sequence. The processor is used to control the driving motor 22 to move the reagent kit 210 to the initial position in response to the completion of the corresponding operation of the reagent kit 210 at the first working position, and the processor is further used to control the driving motor 22 to move the reagent kit 210 from the initial position to the second working position.

[0053] Specifically, the working positions of the loading seat 21 may include a first detection position, a liquid transfer position, a loading and unloading position, etc. When the POCT blood cell analyzer further includes a fluorescence detection component 50, the working position may further include a second detection position, and the fluorescence detection component 50 is used to perform fluorescence detection on the reagent card located at the second detection position. The first working position and the second working position of this embodiment may be two working positions adjacent in time sequence in the above-mentioned working positions during the detection process. Or, when the liquid transfer position includes the liquid transfer positions of multiple cell bodies 211, the first working position and the second working position may also be two positions adjacent in time sequence among the multiple liquid transfer positions. The working positions adjacent in time sequence are working positions with time sequence correlation in the detection process of the POCT blood cell analyzer. For example, after the POCT blood cell analyzer starts detection, it is necessary to move the loading seat 21 to the first working position and then move the loading seat 21 to the second working position to complete a certain operation.

[0054] Furthermore, the POCT blood cell analyzer may pre-store multiple preset steps corresponding to the working positions. For example, when the driving motor 22 drives the loading seat 21 to move from the initial position to the first detection position, the driving motor 22 needs to move the first preset step; when the driving motor 22 drives the loading seat 21 to move from the initial position to the second detection position, the driving motor 22 needs to move the second preset step; when the driving motor 22 drives the loading seat 21 to move from the initial position to the loading and unloading position, the driving motor 22 needs to move the third preset step, etc., so that the processor can directly call the corresponding preset steps when controlling the driving motor 22 to move to the preset position. The method is simple and easy to implement, reducing the operation process.

[0055] In the embodiment of the present application, the processor of the POCT blood cell analyzer controls the driving motor 22 to move the reagent kit 210 to the initial position in response to the completion of the corresponding operation of the reagent kit 210 at the first working position, so that the driving motor 22 drives the loading seat 21 to continue to move from the initial position to the second working position. The driving motor 22 of this embodiment realizes the positioning of the driving motor 22 by defining the initial position, so as to reduce the usage frequency of position detection sensors, etc., reduce the driving cost, and further reduce the instrument cost of the POCT blood cell analyzer.

[0056] Furthermore, the POCT blood cell analyzer further includes a fluorescence detection component 50 disposed on the base 10. The loading base 21 is further configured to receive a reagent card. The fluorescence detection component 50 is configured to perform fluorescence detection on the reagent card located at the second detection position, and the impedance detection component 40 is configured to perform impedance detection on the reagent kit 210 located at the first detection position. Wherein, the reagent card is added with a sample to be tested. The fluorescence detection component 50 may include a light generator and a light receiver. The light generator is configured to emit a detection light beam so that the detection light beam irradiates the sample to be tested on the reagent card. The sample to be tested emits fluorescence under the action of the detection light beam. The light receiver is configured to receive the excitation light of the sample to be tested and characterize the blood cell characteristics of the sample to be tested according to the intensity of the excitation light.

[0057] The POCT blood cell analyzer may include a detection optocoupler. The detection optocoupler is disposed in the base 10 and corresponds to the initial position. The detection optocoupler is configured to identify whether the loading base 21 is located at the initial position, so that the drive motor 22 can accurately move the loading base 21 to the specified position. The processor is configured to: control the drive motor 22 to drive the loading base 21 to move the first number of steps from the initial position to the first detection position; in response to the completion of the impedance detection of the reagent kit 210, control the drive motor 22 to drive the loading base 21 to move back the first number of steps to return to the initial position; control the drive motor 21 to drive the loading base 21 to move the second number of steps to move the loading base 21 to the second detection position.

[0058] It can be understood that before moving to the first detection position, the processor may be configured to control the drive motor 22 to move the third number of steps to move the loading base 21 from the initial position to the liquid transfer position. The drive motor 22 and the lifting motor 31 assist the liquid transfer member 32 to perform a liquid transfer operation and obtain a first solution to be tested. The liquid transfer member 32 adds the first solution to be tested to the detection pool. The processor continues to control the drive motor 22 to move back the third number of steps and make the loading base 21 located at the initial position. In response to the loading base 21 being located at the initial position, the processor controls the drive motor 22 to move the first number of steps to move the loading base 21 from the initial position to the first detection position. The impedance detection component 40 performs a counting test of the first detection item on the first solution to be tested in the detection pool of the reagent kit 210. In response to the completion of the first detection item test, the processor controls the drive motor 22 to move back the first number of steps to make the loading base 21 located at the initial position, and controls the drive motor 22 to move the third number of steps from the initial position to continue to move the loading base 21 to the liquid transfer position. The liquid transfer assembly 30 performs a liquid transfer operation on each cell body 211 of the reagent kit 210 and obtains a second solution to be tested. The second solution to be tested is stored in the detection pool. The processor continues to control the drive motor 22 to move back the third number of steps and controls the drive motor 22 to move the second number of steps to move the loading base 21 from the initial position to the second detection position. The impedance detection component 40 continues to perform a counting test of the second detection item on the second solution to be tested in the detection pool.

[0059] In the above manner, the POCT hematology analyzer of this embodiment can complete the liquid transfer operation and the detection operation with the assistance of a horizontal motor for the reagent kit 210, realizing the tests of the first detection item and the second detection item. It has high driving efficiency, occupies a small space when the motor is driving, has a concise structure, and greatly reduces the instrument cost of the POCT hematology analyzer.

[0060] In one embodiment, the POCT hematology analyzer further includes a shielding component 60. Optionally, in one implementation, as Figure 3 shown, the shielding component 60 can be fixedly arranged on the base body 10, and cover the base body 10 and the internal reagent kit 210 and the impedance detection component 40. The fluorescence detection component 50 and the liquid transfer component 30 are arranged outside the shielding component 60. The shielding component 60 forms a shielding space. When impedance detection is performed, the reagent kit 210 is located in the shielding space formed by the shielding component 60, and the electrode connecting piece 41 is electrically connected to the electrode on the reagent kit 210. The CBC analog circuit board card is located outside the shielding space to reduce the interference of the electromagnetic signal generated by the CBC analog circuit board card on the electrical pulse signal generated during the electrical connection process, and improve the accuracy of impedance detection.

[0061] Optionally, in other implementations, the shielding component 60 can be movably connected or rotatably connected to the base body 10. When the shielding component 60 rotates to a certain angle, the shielding component 60 and the side plate of the base body 10 jointly form a shielding space, so that the reagent kit 210 and the electrode connecting piece 41 are located in the shielding space, and the CBC analog circuit board card is located outside the shielding space, reducing the interference of the electromagnetic signal generated by the CBC analog circuit board card on the electrical pulse signal generated during the electrical connection process.

[0062] The above are only the embodiments of the present application, and do not limit the patent scope of the present application accordingly. All equivalent structural or equivalent process transformations made by using the content of the specification and drawings of the present application, or directly or indirectly applied in other related technical fields, are equally included in the patent protection scope of the present application.

Claims

1. A POCT blood cell analyzer, characterized in that, Comprising: A base body; A transfer assembly, disposed on the base body, including a loading base and a driving motor, the loading base being used for carrying a reagent kit, and the driving motor being used for driving the loading base to move in the horizontal direction; A liquid transfer assembly, disposed on the base body, including a lifting motor and a liquid transfer member, the lifting motor being used for driving the liquid transfer member to move in the vertical direction; Wherein, the reagent kit includes a plurality of cell bodies arranged linearly, and the driving motor is used for driving the loading base to move so that the plurality of cell bodies are respectively located below the liquid transfer member, and the liquid transfer member is used for performing a liquid transfer operation on the plurality of cell bodies.

2. The POCT blood cell analyzer according to claim 1, wherein, The POCT blood cell analyzer further includes an impedance detection assembly, the impedance detection assembly including an electrode connection member, and the driving motor is used for driving the loading base to move to a first detection position so that the electrodes on the reagent kit are elastically docked with the electrode connection member.

3. The POCT blood cell analyzer according to claim 2, wherein The electrode connection member includes an electrode bushing, a first electrode and a second electrode, the base body includes a side plate, the electrode bushing is disposed on the side plate, the first electrode and the second electrode are respectively fixed on the electrode bushing, the loading base is located at the first detection position, and the first electrode and the second electrode are respectively electrically connected to the electrodes on the reagent kit.

4. The POCT blood cell analyzer according to claim 1, characterized in that, The POCT blood cell analyzer further includes an impedance detection assembly, and the driving motor is used for driving the loading base to move to a plurality of working positions to load and unload the reagent kit, and to enable the reagent kit to receive the liquid transfer operation of the liquid transfer assembly and the detection operation of the impedance detection assembly at different working positions.

5. The POCT blood cell analyzer according to claim 4, wherein, The working positions include a loading / unloading working position, and a movable hatch door is movably disposed on the side surface of the base body, and the driving motor is used for driving the loading base to abut against and open the movable hatch door to receive or unload the reagent kit.

6. The POCT blood cell analyzer according to claim 4, wherein, The working positions include a first detection position and a liquid transfer position, the driving motor is used for moving the reagent kit to the liquid transfer position, the liquid transfer assembly is used for transferring liquids in the plurality of cell bodies at the liquid transfer position to prepare a first test solution, and the driving motor is further used for moving the reagent kit to the first detection position so that the impedance detection assembly performs a counting test on the first detection item of the first test solution; The driving motor is further used for moving the reagent kit to the liquid transfer position, the liquid transfer member is further used for transferring liquids in the plurality of cell bodies at the liquid transfer position to prepare a second test solution, and the driving motor is further used for moving the reagent kit to the first detection position so that the impedance detection assembly performs a counting test on the second detection item of the second test solution.

7. The POCT blood cell analyzer according to claim 6, wherein The cell body includes a detection cell and a non-detection cell, the impedance detection assembly is used for testing the first test solution in the detection cell, the driving motor is used for moving the detection cell below the liquid transfer member, and the liquid transfer assembly is used for transferring the remaining first test solution in the detection cell to the non-detection cell and transferring the second test solution to the detection cell so that the impedance detection assembly tests the second test solution.

8. The POCT blood cell analyzer according to claim 4, wherein The POCT blood cell analyzer further includes a processor, which is connected to the drive motor. The processor is used to control the rotation speed and / or rotation time of the drive motor to adjust at least one parameter of the movement time, movement distance, and movement speed of the loading seat, so that the reagent kits are respectively located at a plurality of the working positions.

9. The POCT blood cell analyzer according to claim 4, wherein The working positions include a first working position and a second working position that are adjacent in time sequence. The processor is used to control the drive motor to move the reagent kit to the initial position in response to the completion of the corresponding operation of the reagent kit at the first working position. The processor is further used to control the drive motor to move the reagent kit from the initial position to the second working position.

10. The POCT blood cell analyzer according to claim 9, characterized in that, The POCT blood cell analyzer further includes a fluorescence detection component disposed on the seat body. The loading seat is further used to receive a reagent card. The fluorescence detection component is used to perform fluorescence detection on the reagent card located at the second detection position, and the impedance detection component is used to perform impedance detection on the reagent kit located at the first detection position; Wherein, the processor is used for: Controlling the drive motor to drive the loading seat to move a first number of steps from the initial position to the first detection position; In response to the completion of the impedance detection of the reagent kit, controlling the drive motor to drive the loading seat to move backward a first number of steps and return to the initial position; Controlling the drive motor to drive the loading seat to move a second number of steps to move the loading seat to the second detection position.

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