Preparation method of antibacterial deodorant

Abstract

The invention discloses a preparation method of an antibacterial deodorant, and belongs to the field of fine chemicals. A quaternary ammonium salt compound, a polysorbate compound, an alcohol compound, a carboxylate compound, plant essential oil and the like are used as raw materials, and the antibacterial deodorant is obtained through two steps of deodorant preparation and deodorant rate evaluation of the deodorant. The deodorant has a bacteriostatic effect, and can quickly adsorb and digest organic odor molecules to achieve the effect of removing peculiar smell. The deodorant is simple in preparation process, clean in raw materials, environment-friendly, safe, low in cost, free of pungent peculiar smell and adjustable in faint scent type smell, can be widely applied to peculiar smell elimination of indoor and outdoor environments in the public health field of semi-closed and closed public health, especially elimination of peculiar smell remaining on the body after people eat hot pots, and has market popularization value.

Description

Technical Field

[0001] The present invention belongs to the technical field of daily chemical products, and particularly relates to a preparation method of an antibacterial deodorant. Background Art

[0002] In daily life and industrial production, the problem of odor is widespread and brings many troubles to people. For example, in the food processing and consumption industries, hot pots, soup pots, etc., as an important part of traditional Chinese food culture, their unique flavors are often accompanied by strong odors remaining on clothes, tableware, etc. The odors emitted for a long time not only pose hazards to the health of workers and consumers, but also have negative impacts on the surrounding environment and the lives of residents. Moreover, bacteria (such as Escherichia coli, Staphylococcus aureus) are easily bred in high-temperature cooking environments. However, traditional deodorants are mainly divided into physical deodorants and chemical deodorants. Physical deodorants adsorb or cover up odors, but cannot fundamentally eliminate the odor source, and the effect is short-lived; although chemical deodorants can decompose odor substances through chemical reactions, their components are relatively less safe, may cause harm to the environment and the human body, and even produce new odors, having the following defects: 1) lack of antibacterial function, and residual food residues are likely to cause microbial contamination; 2) chemically synthesized components may irritate the skin or produce secondary odors; 3) the action time is short, and frequent use is required. Therefore, providing a production method of a hot pot deodorant with high efficiency in deodorizing, long-term antibacterial effect, simple composition, low cost, friendly to the human body and the environment, and safe and mild has important application value and practical significance.

[0003] There is currently a method for preparing a deodorant, such as the "Reactive Deodorant with Bactericidal and Deodorizing Functions and Its Preparation Method" with the application number CN202111391020.2, which was published on May 23, 2023. The disclosed method is as follows: A reactive deodorant with bactericidal and deodorizing functions consists of a surfactant (0.5 - 5%, one or two of dodecyl dimethyl ammonium chloride and ditridecyl quaternary ammonium salt), an odor reaction agent (1 - 5%, one or two of corn extract, oat starch, and amino acids in soybeans), a deodorant aid (1 - 8%, composed of deodorant aid one and two, the former being one or two of diethylene glycol and ethanol, and the latter being one or two of citric acid and benzoic acid), a humectant (0.1 - 0.4%, diethylene glycol), an emulsifier (1 - 4%, one or two of coconut alcohol, hydrogenated castor oil, and coconut glucoside), a bactericide (0.1 - 0.5%, didodecyldimethylammonium chloride), deionized water (80 - 90%), and an aromatic agent (1 - 2%). The preparation method is as follows: First, mix deionized water, deodorant aid one, and the humectant in a ratio of 80 - 90%, 1 - 5%, and 0.1 - 0.4% to obtain mixture one, heat it to 40 - 80°C, stir at a speed of 200 - 800 r / min for 5 - 60 min, and then cool it to 38 - 60°C; then, in a ratio of 1 - 5%, 1 - 3%, 0.1 - 0.5%, and 0.5 - 5%, successively mix the odor reaction agent, deodorant aid two, bactericide, and surfactant, and stir at a speed of 200 - 800 r / min for 5 - 60 min at 38 - 60°C to obtain mixture two; finally, mix the emulsifier and aromatic agent in a ratio of 1 - 4% and 1 - 2%, stir at a speed of 200 - 800 r / min for 10 - 80 min, and cool it to room temperature to obtain the deodorant. The method of this patent has the following deficiencies: (1) The raw materials required for the product are relatively complex, the cost of some raw materials is relatively high, and natural components such as corn extract and oat starch are easily affected by fluctuations in raw material quality, resulting in unstable product performance and a reduction in the deodorization rate of the product; (2) There are many production steps, the process is complex, it takes a long time, and the multiple mixing and stirring and step-by-step addition of components during the preparation process lead to a reduction in production efficiency, making it difficult to meet the needs of large-scale production, difficult to promote the technology, and with high production costs; (3) Although this method emphasizes solving the problems of existing products, it does not mention the detailed comparison of test data on key performance indicators (such as quantified data on deodorization efficiency, comparison of bactericidal broad-spectrum, etc.), lacks quantified verification data, and the actual bactericidal and deodorizing efficiency may not meet the expectations in complex and diverse actual scenarios. Summary of the Invention

[0004] The object of the present invention is: Aiming at the problems in the existing field of catering deodorants, such as high cost, complex process, insufficient antibacterial performance, short action time, and single deodorization mechanism, to provide a method for making an antibacterial deodorant, which has the characteristics of being able to effectively remove odors, having high antibacterial efficiency, simple ingredients, low cost, being easy to produce, and being friendly to humans and the environment.

[0005] The mechanism of the present invention is as follows: The synergistic effect of quaternary ammonium salts and carboxylates realizes the dual functions of sterilization and deodorization. The carboxylate has a large specific surface area and a special porous structure, so it has a strong deodorization ability. On the one hand, it relies on physical adsorption to fix odor molecules by van der Waals force to reduce the odor concentration in the air. On the other hand, some groups in its molecules can react chemically with odor molecules, such as neutralizing acidic odor substances such as hydrogen sulfide and organic acids, or complexing with basic odor substances, converting odors into odorless or less odorous substances. It can also form a protective film on the object surface to prevent the volatilization of odor molecules in the object, reduce the contact and adsorption of external odor molecules with the object, and prevent the generation and diffusion of odors from the source and propagation path. As a cationic surfactant, the quaternary ammonium salt has a molecular structure containing a long-chain alkyl group and a positively charged quaternary ammonium group. Since the surface of bacteria is negatively charged, the quaternary ammonium salt is adsorbed on the surface of bacteria by the electrostatic attraction between the cation and the anion on the surface of the bacteria, changing the permeability of the bacterial cell membrane, causing the leakage of key substances in the cell such as amino acids and nucleotides, interfering with the normal metabolism and physiological functions of bacteria, and also denaturing bacterial proteins, achieving the purpose of efficient sterilization. At the same time, it has a broad-spectrum sterilization characteristic, is effective against a variety of bacteria such as Gram-positive bacteria and Gram-negative bacteria, has significant and rapid sterilization, good stability at room temperature, can be stored for a long time, low toxicity, little irritation to the skin and mucous membranes, and is safe to use.

[0006] The technical solution to achieve the invention purpose is: A preparation method of an antibacterial deodorant, using quaternary ammonium salt compounds, carboxylate compounds, polysorbate compounds, alcohols and plant essential oils as raw materials, and obtaining a highly efficient deodorant through two steps: deodorant preparation and evaluation of the deodorization rate of the deodorant. The specific steps of the method are as follows: (1) Deodorant preparation First, weigh 0.05 - 5.0% of quaternary ammonium salt compounds, 0.01 - 2.0% of polysorbate compounds and 0.01 - 2.0% of carboxylate compounds in sequence according to mass percentage and place them in a reaction kettle. Then add 1.0 - 10.0% of alcohol compounds, and then add pure water. Next, stir at 30 - 80 °C for 20 - 50 min to dissolve and mix evenly. Finally, add 0.01 - 2.0% of plant essential oil and stir and mix evenly for 5 - 10 min to prepare a plant-fragrant deodorant. The quaternary ammonium salt compounds include one or more of benzalkonium chloride, benzalkonium bromide, didodecyldimethylammonium chloride, didodecyldimethylammonium bromide, etc.; the polysorbate compounds include one or more of polysorbate 40, polysorbate 60, polysorbate 65, polysorbate 80, etc.; the alcohol compounds include one or more of ethanol, n-propanol, isopropanol, chlorobutanol, etc.; the carboxylate compounds include one or more of sodium acetate, sodium oxalate, potassium citrate, zinc propionate, etc.; the plant essential oils include one or more of lemon essential oil, tea essential oil, jasmine essential oil, etc.; (2) Evaluation of the deodorization rate of the deodorant After the completion of step (1), first take 5-10 pieces of 5cm*5cm cloth strips of the same material, then spray 0.1-1g of odorant at the center point 2-10cm from the surface of the cloth strip, spray continuously 1-4 times, then spray 0.1-1g of plant fragrance deodorant at the same position (1-4 times), then use the nose smell method to judge the odor removal of the cloth strip at the center of the test area within 0-30min, and finally use the 6-level representation method of malodor intensity to rate and calculate the deodorization rate. The cloth strips are blank control group and trial test group, the odorant is Hengyue brand pure plant fermentation extract formula spray, and the members of the nose smell method odor judgment are composed of 5-20 people.

[0007] Calculation formula: Deodorization rate = (odor intensity score before deodorization - odor intensity score after deodorization) / odor intensity score before deodorization * 100%.

[0008] Note: Odor level 1 means no odor; odor level 2 means no obvious odor; odor level 3 means slight odor; odor level 4 means moderate odor; odor level 5 means strong odor; odor level 6 means unbearable odor.

[0009] After the present invention adopts the above technical solution, the main effects are as follows: (1) The main raw materials of the present invention are widely used carboxylate odor neutralizers and quaternary ammonium salt disinfectants and other auxiliary materials. These raw materials have low procurement costs and have no adverse effects on the human body and the environment at reasonable concentrations. At the same time, the various components have synergistic effects and meet the production requirements of high-efficiency deodorizers.

[0010] (2) The production process is simple, the operation is easy, the energy consumption is low, it is green, environmentally friendly and pollution-free, it is conducive to promotion and suitable for large-scale production.

[0011] (3) The present invention uses sensory identification, antibacterial testing, gas chromatography-mass spectrometry and other methods to quantify the deodorization efficiency and antibacterial properties of the product, and specifically solves the odor and bacteria problems in hot pot, soup pot and other business premises, as well as the odor remaining on clothing after eating, to meet the needs of the people and the market. DETAILED DESCRIPTION

[0013] The present invention is further described in detail below in conjunction with specific embodiments: Example

[0014] The specific steps of a method for preparing an antibacterial deodorant are as follows: Deodorant preparation First, weigh 0.2% of quaternary ammonium salt compounds, 0.1% of polysorbate compounds, and 1% of carboxylate compounds in sequence according to mass percentage and place them in a reaction kettle. Then add 4.3% of alcohol compounds, and then add pure water. Next, stir at 50 °C for 20 min to dissolve and mix evenly. Finally, add 0.05% of plant essential oil and stir and mix evenly for 10 min to obtain a plant fragrance deodorant. The quaternary ammonium salt compounds include one or more of benzalkonium chloride, benzalkonium bromide, didodecyldimethylammonium chloride, didodecyldimethylammonium bromide, etc.; the polysorbate compounds include one or more of polysorbate 40, polysorbate 60, polysorbate 65, polysorbate 80, etc.; the alcohol compounds include one or more of ethanol, n-propanol, isopropanol, chlorobutanol, etc.; the carboxylate compounds include one or more of sodium acetate, sodium oxalate, potassium citrate, zinc propionate, etc.; the plant essential oil includes one or more of lemon essential oil, tea essential oil, jasmine essential oil, etc. (2)Evaluation of the deodorization rate of the deodorant After the completion of step (1), first take 7 pieces of cloth strips of the same material with a size of 5 cm * 5 cm. Then spray 0.2931 g of odorant at the central point 10 cm above the surface of the cloth strip, spray continuously for 2 times. Then spray 0.3 g of the plant fragrance deodorant (2 times) at the same position. Subsequently, at different time points of 5, 10, 15, 20, 25, and 30 min, use the nose-smelling method to judge the removal of odor from the cloth strip at the central position of the test area. Finally, use the 6-level representation method of malodor intensity for rating and scoring, and calculate the deodorization rate. The cloth strips are blank control groups and trial detection groups. The odorant is a pure plant fermentation extraction formula spray of Hengyue brand. The members for judging the odor by the nose-smelling method consist of 10 people. The experimental results show that the deodorization rate of the deodorant within 30 minutes is positively correlated with time. Among them, at 5 minutes, the deodorization rate is 18% and the score is 4.92 points; at 10 minutes, the deodorization rate is 26% and the score is 4.44 points; at 15 minutes, the deodorization rate is 42% and the score is 3.48 points; at 20 minutes, the deodorization rate is 58% and the score is 2.52 points; at 25 minutes, the deodorization rate has reached 69% and the score is 1.86 points; at 30 minutes, the deodorization rate reaches 88% and the score is 0.72 points, and the odor is basically removed; the score of the blank control group is 5.41 (30 minutes), and the deodorization rate is 9.84%, and the odor residue is relatively high. Example

[0015] A preparation method of an antibacterial deodorant is the same as that in Example 1, wherein: In step (1), 0.2% of quaternary ammonium salt compounds, 0.1% of polysorbate compounds, 4.3% of alcohol, 0.8% of carboxylate, and 0.05% of plant essential oil, the stirring speed is 200 rpm, the stirring temperature is 50 °C, and the stirring time is 15 min; In step (2), the scores and deodorization rates of the deodorant at 5, 10, 15, 20, 25, 30 min of reaction and the blank group were measured. The experimental results show that the deodorization rate of the deodorant within 30 minutes is positively correlated with time. Among them, at 5 minutes, the deodorization rate is 12% and the score is 5.28; at 10 minutes, the deodorization rate is 25% and the score is 4.5; at 15 minutes, the deodorization rate reaches 38% and the score is 3.72; at 20 minutes, the deodorization rate is 51% and the score is 2.94; at 25 minutes, the deodorization rate has reached 64% and the score is 2.16; at 30 minutes, the deodorization rate reaches 84% and the score is 0.96, and the odor is basically removed; the score of the blank control group is 5.41 points (30 minutes) and the deodorization rate is 7.03%, and the odor residue is relatively high. Example

[0016] A preparation method of an antibacterial deodorant is the same as that in Example 1, wherein: In step (1), 0.1% of quaternary ammonium salt compound, 0.1% of polysorbate compound, 4.3% of alcohol, 0.5% of carboxylate, 0.05% of plant essential oil, the stirring speed is 200 rpm, the stirring temperature is 50 °C, and the stirring time is 25 min; In step (2), the scores and deodorization rates of the deodorant at 5, 10, 15, 20, 25, 30 min of reaction and the blank group were measured.

[0017] The experimental results show that the deodorization rate of the deodorant within 30 minutes is positively correlated with time. Among them, at 5 minutes, the deodorization rate is 14.58% and the score is 5.13; at 10 minutes, the deodorization rate is 29.33% and the score is 4.24; at 15 minutes, the deodorization rate is 36.47% and the score is 3.81; at 20 minutes, the deodorization rate is 54.73% and the score is 2.72; at 25 minutes, the deodorization rate is 69.77% and the score is 1.81; at 30 minutes, the deodorization rate reaches 81.34% and the score is 1.12, and the odor is basically removed; the score of the blank control group is 5.67 points (30 minutes) and the deodorization rate is 5.46%, and the odor residue is relatively high.

[0018] Experimental results 1. Influence of different quaternary ammonium salt mass ratios on the deodorization rate of antibacterial deodorant 2. Influence of different alcohol volume ratios on the deodorization rate of antibacterial deodorant 3. Influence of different carboxylate mass ratios on the deodorization rate of antibacterial deodorant 4. Antibacterial experiment Bacterial species Inhibition zone diameter 1 (mm) Inhibition zone diameter 2 (mm) Inhibition zone diameter 3 (mm) Average inhibition zone diameter (mm) Escherichia coli 21.68 21.45 22.12 21.75 Staphylococcus aureus 26.3 27.3 26.5 26.7 5. Gas chromatography - mass spectrometry detection results of NO source odor treated by deodorant 6. Detection results of physical and chemical indexes of deodorant 7. Comparison of the stability of this product with commercially available odor eliminators.

Claims

1. A preparation method of an antibacterial and odor-eliminating agent, characterized in that, It includes the following steps: (1) Preparation of deodorant First, weigh 0.05 - 5.0% of quaternary ammonium salt compounds, 0.01 - 2.0% of polysorbate compounds, and 0.01 - 2.0% of carboxylate compounds in sequence by mass percentage and place them in a reaction kettle. Then add 1.0 - 10.0% of alcohol compounds, and then add pure water. Next, stir at 30 - 80 °C for 20 - 50 min to dissolve and mix evenly. Finally, add 0.01 - 2.0% of plant essential oil and stir for 5 - 10 min to obtain a plant - fragrant deodorant. The quaternary ammonium salt compounds include one or more of benzalkonium chloride, benzalkonium bromide, didodecyldimethylammonium chloride, didodecyldimethylammonium bromide, etc.; the polysorbate compounds include one or more of polysorbate 40, polysorbate 60, polysorbate 65, polysorbate 80, etc.; the alcohol compounds include one or more of ethanol, n - propanol, isopropanol, chlorobutanol, etc.; the carboxylate compounds include one or more of sodium acetate, sodium oxalate, potassium citrate, zinc propionate, etc.; the plant essential oil includes one or more of lemon essential oil, tea - fragrant essential oil, jasmine essential oil, etc.; (2) Evaluation of deodorization rate of deodorant After the completion of step (1), first take 5 - 10 pieces of cloth strips of the same material with a size of 5 cm * 5 cm. Then spray 0.1 - 1 g of odorant at the central point 2 - 10 cm from the surface of the cloth strips, and spray continuously for 1 - 4 times. Then spray 0.1 - 1 g of plant - fragrant deodorant (1 - 4 times) at the same position. Subsequently, within 0 - 30 min, use the nose - smelling method to judge the removal of odor from the cloth strips at the central position of the test area. Finally, use the 6 - level representation method of odor intensity for rating and calculate the deodorization rate. The cloth strips are blank control groups and test groups for trial detection. The odorant is a pure - plant - fermented extraction formula spray of Hengyue brand. The members for judging odor by the nose - smelling method consist of 5 - 20 people.

2. The detection of an antibacterial and deodorizing agent according to claim 1, characterized in that, It includes the following steps: Evaluate the antibacterial effect of chemical reagent - type disinfection products according to the "Technical Requirements for Safety Evaluation of Disinfectants" GB / T 38497 - 2020, and judge the antibacterial effect through the antibacterial ring test; test the deodorization efficiency using gas chromatography - mass spectrometry according to the "Textiles - Determination of Odor Eliminating Performance" GB / T 33610 - 2019; detect the physical and chemical indexes according to the "Determination of pH Value of Aqueous Solution of Surfactants - Potentiometric Method" GB / T 6368; conduct sensory evaluation on sensory characteristics such as odor and appearance according to national standards such as the "General Principles of Sensory Analysis Methods" GB 10220 - 88 and the "Terms of Sensory Analysis" GB 10221.1 - 4.

3. The preparation method of the antibacterial deodorant according to claim 1, characterized in that: In step (1), 0.2% of quaternary ammonium salt compounds, 0.1% of polysorbate compounds, 4.3% of alcohol, 1% of carboxylate, 0.05% of plant essential oil, the stirring speed is 200 rpm, the stirring temperature is 50 °C, and the stirring time is 20 min; In step (2), the spraying position of each cloth strip is 10 cm obliquely above its center point, and the amount of each spraying is 2 times (0.2931 g). The judging group consists of 10 people, and the scores and deodorization rates of the deodorant at 5, 10, 15, 20, 25, 30 min and the blank group are measured. The experimental results show that the deodorization rate of the deodorant within 30 minutes is positively correlated with time. Among them, at 5 minutes, the deodorization rate is 18% and the score is 4.92; at 10 minutes, the deodorization rate is 26% and the score is 4.44; at 15 minutes, the deodorization rate is 42% and the score is 3.48; at 20 minutes, the deodorization rate is 58% and the score is 2.52; at 25 minutes, the deodorization rate has reached 69% and the score is 1.86; at 30 minutes, the deodorization rate reaches 88% and the score is 0.72, and the odor is basically removed; the score of the blank control group is 5.41 (30 minutes), and the deodorization rate is 9.84%, with a relatively high odor residue.

4. The preparation method of the antibacterial deodorant according to claim 1, wherein: In step (1), 0.2% of quaternary ammonium salt compound, 0.1% of polysorbate compound, 4.3% of alcohol, 0.8% of carboxylate, 0.05% of plant essential oil, the stirring speed is 200 rpm, the stirring temperature is 50 °C, and the stirring time is 15 min; In step (2), the scores and deodorization rates of the deodorant at 5, 10, 15, 20, 25, 30 min and the blank group are measured. The experimental results show that the deodorization rate of the deodorant within 30 minutes is positively correlated with time. Among them, at 5 minutes, the deodorization rate is 12% and the score is 5.28; at 10 minutes, the deodorization rate is 25% and the score is 4.5; at 15 minutes, the deodorization rate reaches 38% and the score is 3.72; at 20 minutes, the deodorization rate is 51% and the score is 2.94; at 25 minutes, the deodorization rate has reached 64% and the score is 2.16; at 30 minutes, the deodorization rate reaches 84% and the score is 0.96, and the odor is basically removed; the score of the blank control group is 5.41 (30 minutes) and the deodorization rate is 7.03%, with a relatively high odor residue.

5. The preparation method of the antibacterial deodorant according to claim 1, wherein: In step (1), 0.1% of quaternary ammonium salt compound, 0.1% of polysorbate compound, 4.3% of alcohol, 0.5% of carboxylate, 0.05% of plant essential oil, the stirring speed is 200 rpm, the stirring temperature is 50 °C, and the stirring time is 25 min; In step (2), the scores and deodorization rates of the deodorant at 5, 10, 15, 20, 25, 30 minutes of reaction and the blank group were measured. The experimental results show that the deodorization rate of the deodorant within 30 minutes is positively correlated with time. Among them, the deodorization rate at 5 minutes is 14.58% and the score is 5.13; the deodorization rate at 10 minutes is 29.33% and the score is 4.24; the deodorization rate at 15 minutes is 36.47% and the score is 3.81; the deodorization rate at 20 minutes is 54.73% and the score is 2.72; the deodorization rate at 25 minutes is 69.77% and the score is 1.81; the deodorization rate at 30 minutes reaches 81.34% and the score is 1.12, basically removing the odor; the score of the blank control group is 5.67 points (30 minutes) and the deodorization rate is 5.46%, with a relatively high odor residue.