Test device and system for cross matching of blood

By designing a cross-matching test device containing the negative pressure effect of the limiting mechanism and rubber sleeve, the problems of blood sample purity and operation complexity in traditional devices are solved, and closed blood cross-test and integrated operation are realized, ensuring the accuracy of the test data and simplifying the operation process.

CN120254296AInactive Publication Date: 2025-07-04HANGZHOU TRADITIONAL CHINESE MEDICINE HOSPITAL (HANGZHOU TRADITIONAL CHINESE MEDICINE HOSPITAL AFFILIATED TO ZHEJIANG UNIV OF TRADITIONAL CHINESE MEDICINE)
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Patent Information

Application Number
CN202510270591.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-07
Publication Date
2025-07-04
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The traditional cross-matching test device lacks an effective closed system, which makes it difficult to ensure the purity of blood samples, and the operation is complicated, making it difficult to achieve integrated operation.

Method used

A test device including a base, test device body, carrier seat, circulation seat, cross cavity, fixing seat, collection seat, limit seat, sealing cover and rubber sleeve is designed. The limiting mechanism and connection mechanism are used to achieve convenient collection, flow diversion and cross test of blood. The negative pressure effect of the rubber sleeve is used to automatically introduce blood and enter the bottom collection tube, and a closed cross test is achieved by combining the sinking groove and flow hole.

Benefits of technology

The closed and integrated operation of blood cross-test is achieved, ensuring the accuracy of the test data and simplifying the operation process.

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Abstract

The invention belongs to the technical field of medical tests, and particularly relates to a test device and system for cross matching of blood, the test device comprises a base, a test device main body is fixedly mounted on the base, a bearing seat is fixedly mounted on the inner side of the test device main body, and a circulation seat is fixedly arranged on the bearing seat; a cross cavity is formed in the inner side of the circulation base, a fixing base is fixedly arranged on the bearing base, and a loading mechanism is arranged on the fixing base. A sinking groove formed in the inner side of a collection seat is used for guiding blood in a bottom collection pipe, after the bottom collection pipe completes blood collection, the blood enters the sinking groove due to the downward gravity factor of the blood and automatically flows into a flowing hole formed in the collection seat and located in the inner side of the sinking groove in a penetrating mode, and then the blood is collected through the flowing hole. Along with the flowing of blood, the blood enters the inner side of the cross cavity to realize a closed blood cross test, so that the accuracy of blood cross test data is ensured.
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Description

Technical Field

[0001] The present invention belongs to the technical field of medical testing, and specifically relates to a test device and system for cross - matching blood. Background Art

[0002] The cross - matching blood test is an important detection method before clinical blood transfusion, and its main purpose is to ensure that hemolytic transfusion reactions do not occur after the recipient receives the blood from the donor; Traditional cross - matching blood tests usually adopt manual operations, and methods such as centrifugation and observing agglutination reactions are used to judge blood type compatibility.

[0003] The following deficiencies still exist in traditional cross - matching blood test devices: There is a lack of an effective closed system during the blood transfer process, making it difficult to ensure the purity of blood samples; During the blood collection, transfer, and cross - test processes, it is difficult to achieve integrated operation, and the operation is complex. Therefore, a test device and system for cross - matching blood are proposed to address the above problems. Summary of the Invention

[0004] In order to make up for the deficiencies of the prior art and solve at least one of the technical problems proposed in the background art, the present invention proposes a test device and system for cross - matching blood.

[0005] The technical solution adopted by the present invention to solve its technical problems is: A test device and system for cross - matching blood according to the present invention includes a base, on which a test device main body is fixedly installed. Inside the test device main body, a bearing seat is fixedly installed. On the bearing seat, a circulation seat is fixedly provided. Inside the circulation seat, a cross - cavity is opened. On the bearing seat, a fixed seat is fixedly provided, and a loading mechanism is arranged on the fixed seat; At the top of the circulation seat, a collection seat is provided. On the collection seat, a limit seat is fixedly installed, and a limit mechanism is arranged on the limit seat. At the top of the collection seat, a sealing cover is provided, and a connection mechanism is arranged on the sealing cover, and the connection mechanism cooperates with the limit mechanism; At the top of the sealing cover, a rubber sleeve communicated with it is fixedly installed. At the top of the rubber sleeve, a collection mechanism is fixedly installed. Inside the rubber sleeve, a bottom collection tube is fixedly provided. A reserved cavity is arranged between the bottom collection tube and the rubber sleeve. A round hole is opened on the bottom collection tube, and the round hole is communicated with the reserved cavity; Inside the collection seat, a sinking groove is opened. On the collection seat and inside the sinking groove, a flow hole is penetrated, and the flow hole is communicated with the cross - cavity.

[0006] Preferably, the loading mechanism includes a support plate fixedly installed on the top of the fixed seat. A balance plate is fixedly installed on the top of the support plate, and the balance plate is connected to the collection seat.

[0007] Preferably, the limiting mechanism includes a limiting frame fixedly installed inside the limiting seat, and the limiting frame is L-shaped.

[0008] Preferably, the connecting mechanism includes a connecting seat arranged on the sealing cover. An extension plate is fixedly installed at the bottom of the connecting seat, and a limiting rod is fixedly installed at the bottom of the extension plate. The limiting rod is clamped with the limiting frame.

[0009] Preferably, a limiting spring is fixedly arranged on the limiting rod, and one end of the limiting spring away from the limiting rod is connected to the top inside the limiting seat.

[0010] Preferably, the collection mechanism includes a top collection tube fixedly installed on the top of the rubber sleeve. A connecting tube is inserted into one end of the top collection tube away from the rubber sleeve, and a contact tube is fixedly installed on the top of the connecting tube.

[0011] Preferably, the contact tube is made of glass material.

[0012] Preferably, a sealing ring groove is formed on the top of the collection seat, and a sealing ring is fixedly arranged at the bottom of the sealing cover. The sealing ring is in interference fit with the sealing ring groove.

[0013] A test system for cross-matching blood includes a test device, a detection module, and an analysis module. The detection module is located inside the cross cavity, the analysis module is located on the main body of the test device, and the analysis module is electrically connected to the detection module.

[0014] Advantages of the present invention: The present invention provides a test device and system for cross-matching blood. The collection seat arranged on the top of the circulation seat is used to realize the collection place of blood collection, and the blood is introduced into the cross cavity for cross-test. The limiting seat fixedly installed on the collection seat is used to load the limiting mechanism. With the cooperation of the limiting mechanism and the connecting mechanism, the convenient fitting and separation of the collection seat and the sealing cover are realized. When blood needs to be collected, the collection seat and the sealing cover are in a fitting state. When the inside of the collection seat needs to be cleaned, the collection seat and the sealing cover are in a separated state. The limiting mechanism arranged on the limiting seat cooperates with the connecting mechanism to load and limit the sealing cover. The sealing cover arranged on the top of the collection seat is used for blood collection for cross-blood test. The connecting mechanism arranged on the sealing cover cooperates with the limiting mechanism to realize the convenient separation of the collection seat and the sealing cover, realizing an integrated cross-matching blood test; A rubber sleeve connected and communicated therewith is fixedly installed through the top of the sealing cover for loading the top collecting tube. A collecting mechanism fixedly installed through the top of the rubber sleeve is used to collect blood during cross-blood tests. A bottom collecting tube fixedly arranged through the inner side of the rubber sleeve serves as a cavity in contact with the blood. With the cooperation of the rubber sleeve, negative pressure blood enters the inner side of the bottom collecting tube. Specifically, during blood collection, by pressing the rubber sleeve, the air in the reserved cavity is compressed, and since the reserved cavity is connected and communicated with the inner side of the bottom collecting tube, the inner side of the bottom collecting tube is also in a negative pressure state. When the rubber sleeve is released, the rubber sleeve rebounds, and the reserved cavity returns to its original volume, thereby applying pressure to the inner side of the bottom collecting tube, causing the blood to automatically enter the bottom collecting tube and waiting for subsequent test procedures; A sunken groove opened through the inner side of the collecting seat is used to guide the blood inside the bottom collecting tube. After the bottom collecting tube completes blood collection, due to the downward factor of gravity, the blood enters the sunken groove and automatically flows into a flow hole penetrating through the inner side of the sunken groove on the collecting seat. Then, as the blood flows, it enters the inner side of the cross cavity to achieve a closed blood cross test, thereby ensuring the accuracy of blood cross test data. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The drawings described herein are used to provide a further understanding of the present invention and constitute a part of this application. The schematic embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention.

[0016] In the drawings: Figure 1 is a schematic diagram of the overall structure of the present invention; Figure 2 is a schematic diagram of the internal structure of the present invention Figure 1 ; Figure 3 is a schematic diagram of the internal structure of the present invention Figure 2 ; Figure 4 is in the present invention Figure 3 a schematic enlarged view of the structure at position A; Figure 5 is a schematic diagram of the structure of the collecting seat in the present invention; Figure 6 is in the present invention Figure 5 a schematic enlarged view of the structure at position B; Figure 7 is a schematic diagram of the structure of the rubber sleeve in the present invention; Figure 8 is a schematic diagram of the structure of the bottom collecting tube in the present invention; Figure 9 is a schematic diagram of the internal structure of the collecting seat in the present invention.

[0017] Legend Explanation: 1. Base; 2. Main body of the test device; 3. Bearing seat; 4. Flow-through seat; 5. Cross cavity; 6. Fixed seat; 7. Support plate; 8. Balance plate; 9. Collection seat; 10. Sealing cover; 11. Connecting seat; 12. Extension plate; 13. Limiting rod; 14. Limiting spring; 15. Limiting seat; 16. Limiting frame; 17. Rubber sleeve; 18. Top collection pipe; 19. Insertion connection pipe; 20. Contact pipe; 21. Reserved cavity; 22. Bottom collection pipe; 23. Round hole; 24. Sealing ring; 25. Sealing ring groove; 26. Sinking groove; 27. Flow hole. Specific Embodiment

[0018] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0019] The following gives specific embodiments.

[0020] Please refer to Figures 1-9 , the present invention provides a test device and system for cross-matching blood, including a base 1, on which a main body 2 of the test device is fixedly installed, a bearing seat 3 is fixedly installed inside the main body 2 of the test device, a flow-through seat 4 is fixedly arranged on the bearing seat 3, a cross cavity 5 is opened inside the flow-through seat 4, a fixed seat 6 is fixedly arranged on the bearing seat 3, and a loading mechanism is arranged on the fixed seat 6; A collection seat 9 is arranged on the top of the flow-through seat 4, a limiting seat 15 is fixedly installed on the collection seat 9, a limiting mechanism is arranged on the limiting seat 15, a sealing cover 10 is arranged on the top of the collection seat 9, a connecting mechanism is arranged on the sealing cover 10, and the connecting mechanism cooperates with the limiting mechanism; A rubber sleeve 17 communicating with it is fixedly installed on the top of the sealing cover 10, a collection mechanism is fixedly installed on the top of the rubber sleeve 17, a bottom collection pipe 22 is fixedly arranged inside the rubber sleeve 17, a reserved cavity 21 is arranged between the bottom collection pipe 22 and the rubber sleeve 17, and a round hole 23 is opened on the bottom collection pipe 22, and the round hole 23 communicates with the reserved cavity 21; A sinking groove 26 is opened inside the collection seat 9, and a flow hole 27 is penetrated and opened on the collection seat 9 and inside the sinking groove 26, and the flow hole 27 communicates with the cross cavity 5; During operation, the test device main body 2 is loaded through the base 1, and the cross-matching test is completed in cooperation with the test device main body 2 fixedly installed on the base 1. The carrier seat 3 fixedly installed inside the test device main body 2 is used to load the circulation seat 4. During the cross-matching test, the blood fusion and crossover are realized through the circulation seat 4 fixedly arranged on the carrier seat 3. The crossover cavity 5 opened inside the circulation seat 4 is used as the liquid fusion space for the experiment. The fixing seat 6 fixedly arranged on the carrier seat 3 is used to load and fix the loading mechanism. The loading mechanism arranged on the fixing seat 6 is used to limit the collection seat 9, so as to facilitate the subsequent test; The collection seat 9 arranged on the top of the circulation seat 4 is used to realize the collection place of blood collection and introduce the blood into the crossover cavity 5 for crossover test. The limit seat 15 fixedly installed on the collection seat 9 is used to load the limiting mechanism. Under the cooperation of the limiting mechanism and the connecting mechanism, the convenient fitting and separation of the collection seat 9 and the sealing cover 10 are realized. When blood needs to be collected, the collection seat 9 and the sealing cover 10 are in a fitting state. When the inside of the collection seat 9 needs to be cleaned, the collection seat 9 and the sealing cover 10 are in a separated state. The limiting mechanism arranged on the limit seat 15 cooperates with the connecting mechanism to load and limit the sealing cover 10. The sealing cover 10 arranged on the top of the collection seat 9 is used for blood collection in the cross-blood test. The connecting mechanism arranged on the sealing cover 10 cooperates with the limiting mechanism to realize the convenient separation of the collection seat 9 and the sealing cover 10; The rubber sleeve 17 connected and communicated with the top of the sealing cover 10 is fixedly installed to load the top collection tube 18. The collection mechanism fixedly installed on the top of the rubber sleeve 17 is used to realize blood collection during the cross-blood test. The bottom collection tube 22 fixedly arranged inside the rubber sleeve 17 serves as the cavity in contact with the blood. With the cooperation of the rubber sleeve 17, the blood enters the inside of the bottom collection tube 22 under negative pressure. Specifically, during blood collection, by pressing the rubber sleeve 17, the air in the reserved cavity 21 is compressed. And because the reserved cavity 21 is connected and communicated with the inside of the bottom collection tube 22, the inside of the bottom collection tube 22 is also in a negative pressure state. When the rubber sleeve 17 is released, the rubber sleeve 17 rebounds, and the reserved cavity 21 returns to its original volume, so that the inside of the bottom collection tube 22 is pressurized, so that the blood automatically enters the bottom collection tube 22 and waits for the subsequent test process; The sunken groove 26 opened on the inner side of the collection base 9 is used to divert the blood inside the bottom collection tube 22. After the bottom collection tube 22 finishes collecting the blood, due to the downward factor of gravity, the blood enters the sunken groove 26 and automatically flows into the flow hole 27 that penetrates through and is located on the inner side of the sunken groove 26 on the collection base 9. Then, as the blood flows, it enters the inner side of the cross cavity 5 to achieve a closed blood cross-test, thus ensuring the accuracy of the blood cross-test data.

[0021] Furthermore, as Figure 4 shown, the loading mechanism includes a support plate 7 fixedly installed on the top of the fixed base 6. A balance plate 8 is fixedly installed on the top of the support plate 7, and the balance plate 8 is connected to the collection base 9; During operation, the support plate 7 fixedly installed on the top of the fixed base 6 is used to load the balance plate 8, and the balance plate 8 fixedly installed on the top of the support plate 7 is used to limit the two collection bases 9, so that after the two collection bases 9 finish collecting two different kinds of blood, they are ensured to flow into the inner side of the cross cavity 5 at the same rate to complete the blood cross-test and ensure the test accuracy of the data.

[0022] Furthermore, as Figure 6 shown, the limiting mechanism includes a limiting frame 16 fixedly installed inside the limiting seat 15, and the limiting frame 16 is in an L shape; During operation, the limiting frame 16 fixedly installed inside the limiting seat 15 is used to limit the collection base 9, so as to facilitate the convenient separation and fitting of the collection base 9 and the sealing cover 10. And the limiting frame 16 is in an L shape, which can ensure good fitting of the sealing cover 10 relative to the collection base 9.

[0023] Furthermore, as Figure 6 shown, the connecting mechanism includes a connecting seat 11 arranged on the sealing cover 10. An extension plate 12 is fixedly installed at the bottom of the connecting seat 11, and a limiting rod 13 is fixedly installed at the bottom of the extension plate 12. The limiting rod 13 is clamped with the limiting frame 16; During operation, the connecting seat 11 arranged on the sealing cover 10 is used to load the extension plate 12, the extension plate 12 fixedly installed at the bottom of the connecting seat 11 is used to load the limiting rod 13, and through the limiting rod 13 fixedly installed at the bottom of the extension plate 12, after the collection base 9 and the sealing cover 10 are fitted, by clamping the limiting rod 13 on the corresponding limiting frame 16, the stable fitting of the collection base 9 and the sealing cover 10 is realized.

[0024] Furthermore, as Figure 6 shown, a limiting spring 14 is fixedly arranged on the limiting rod 13, and one end of the limiting spring 14 away from the limiting rod 13 is connected to the top inside the limiting seat 15; During operation, the limiting spring 14 fixedly arranged on the limiting rod 13 is used to limit the limiting rod 13. The stress generated when the limiting spring 14 deforms can not only ensure sufficient sealing performance after the collection seat 9 and the sealing cover 10 are fitted, but also improve the convenience of separating the limiting rod 13 from the limiting frame 16. After the limiting rod 13 is separated from the limiting frame 16, the limiting spring 14 drives the limiting rod 13 to contract until it is close to the top of the limiting seat 15, facilitating the next use.

[0025] Further, as Figure 8 shown, the collection mechanism includes a top collection tube 18 fixedly installed at the top of a rubber sleeve 17. One end of the top collection tube 18 away from the rubber sleeve 17 is inserted with an insertion tube 19, and a contact tube 20 is fixedly installed at the top of the insertion tube 19. During operation, the top collection tube 18 fixedly installed at the top of the rubber sleeve 17 is used for loading the insertion tube 19, the insertion tube 19 inserted at one end of the top collection tube 18 away from the rubber sleeve 17 is used for loading the contact tube 20, and the contact tube 20 fixedly installed at the top of the insertion tube 19 is in direct contact with the blood to be tested, thereby realizing the safe and convenient collection of blood.

[0026] Further, as Figure 8 shown, the contact tube 20 is made of glass material; During operation, since the contact tube 20 is made of glass material, it is convenient to clean the contact tube 20.

[0027] Further, as Figure 4 and Figure 9 shown, a sealing ring groove 25 is formed at the top of the collection seat 9, and a sealing ring 24 is fixedly arranged at the bottom of the sealing cover 10. The sealing ring 24 is in interference fit with the sealing ring groove 25; During operation, the sealing ring groove 25 formed at the top of the collection seat 9 is used to cooperate with the sealing ring 24 to realize the sealing performance after the collection seat 9 and the sealing cover 10 are fitted, ensuring the normal collection of blood.

[0028] Further, as Figures 1-9 shown, a test system for cross-matching blood includes a test device, a detection module, and an analysis module. The detection module is located inside the cross-chamber 5, the analysis module is located on the test device main body 2, and the analysis module is electrically connected to the detection module; During operation, the test device is used to perform pre-treatments such as separation, dilution, and labeling on the blood samples of the blood donors and recipients; the detection module uses a microfluidic chip, injects the pre-treated samples into the chip, and detects blood group antigens and antibodies through antigen-antibody reactions; the analysis module automatically analyzes the blood group compatibility between the blood donors and recipients according to the detection results, providing a basis for clinical blood transfusion.

[0029] The foregoing has shown and described the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments, and what is described in the above embodiments and the specification is only to illustrate the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements fall within the scope of the present invention claimed.

Claims

1. A test device for cross-matching blood, comprising a base (1), and a test device main body (2) is fixedly installed on the base (1), characterized in that: A carrier seat (3) is fixedly installed inside the main body (2) of the test device. A circulation seat (4) is fixedly arranged on the carrier seat (3). An intersection cavity (5) is formed inside the circulation seat (4). A fixed seat (6) is fixedly arranged on the carrier seat (3), and a loading mechanism is arranged on the fixed seat (6). A collection seat (9) is arranged on the top of the circulation seat (4). A limit seat (15) is fixedly installed on the collection seat (9), and a limit mechanism is arranged on the limit seat (15). A sealing cover (10) is arranged on the top of the collection seat (9), and a connection mechanism is arranged on the sealing cover (10). The connection mechanism is matched with the limit mechanism. A rubber sleeve (17) communicated with the sealing cover (10) is fixedly installed on the top of the sealing cover (10). An acquisition mechanism is fixedly installed on the top of the rubber sleeve (17). A bottom collection pipe (22) is fixedly arranged inside the rubber sleeve (17). A reserved cavity (21) is arranged between the bottom collection pipe (22) and the rubber sleeve (17). A round hole (23) is formed in the bottom collection pipe (22), and the round hole (23) is communicated with the reserved cavity (21). A sinking groove (26) is formed inside the collection seat (9). A flow hole (27) is formed through the collection seat (9) and located inside the sinking groove (26), and the flow hole (27) is communicated with the intersection cavity (5).

2. The test device for cross-matching blood according to claim 1, wherein: The loading mechanism includes a support plate (7) fixedly installed on the top of the fixed seat (6). A balance plate (8) is fixedly installed on the top of the support plate (7), and the balance plate (8) is connected with the collection seat (9).

3. The test device for cross-matching according to claim 1, characterized in that: The limit mechanism includes a limit frame (16) fixedly installed inside the limit seat (15), and the limit frame (16) is L-shaped.

4. The test device for cross-matching according to claim 3, characterized in that: The connection mechanism includes a connection seat (11) arranged on the sealing cover (10). An extension plate (12) is fixedly installed at the bottom of the connection seat (11). A limit rod (13) is fixedly installed at the bottom of the extension plate (12), and the limit rod (13) is clamped with the limit frame (16).

5. The test device for cross-matching according to claim 4, wherein: A limit spring (14) is fixedly arranged on the limit rod (13), and one end of the limit spring (14) far away from the limit rod (13) is connected with the top inside the limit seat (15).

6. The test device for cross - matching according to claim 1, characterized in that: The acquisition mechanism includes a top collection pipe (18) fixedly installed on the top of the rubber sleeve (17). A plug-in pipe (19) is inserted into one end of the top collection pipe (18) far away from the rubber sleeve (17), and a contact pipe (20) is fixedly installed on the top of the plug-in pipe (19).

7. An experimental device for cross-matching according to claim 6, characterized in that: The contact pipe (20) is made of glass material.

8. The test device for cross-matching blood according to claim 1, characterized in that: A sealing ring groove (25) is formed on the top of the collection seat (9). A sealing ring (24) is fixedly arranged at the bottom of the sealing cover (10), and the sealing ring (24) is in interference fit with the sealing ring groove (25).

9. A test system for cross - matching blood, characterized in that: Including the test device, detection module and analysis module according to any one of claims 1-8, the detection module is located inside the cross cavity (5), the analysis module is located on the test device main body (2), and the analysis module is electrically connected to the detection module.