Trioxynormal saline preparation as well as preparation method and use method thereof

Abstract

The invention provides an ozone normal saline preparation which comprises normal saline, and the normal saline is fused with ozone to form the preparation. The trioxynormal saline preparation is simple to use and operate, and can be operated in a conventional environment; only normal saline and ozone are used as components, can be decomposed into oxygen and hydrogen peroxide after entering a human body for about 15 minutes, do not contain any toxic substances and residues, and are simple, convenient, green and safe; excessive taboo does not exist in use, and the applicability is wider; long-term recycling can be achieved, and the phenomena of drug resistance and the like do not exist.

Description

Technical Field

[0001] The present invention relates to the technical field of pharmaceutical preparations, and specifically relates to a trioxygenated saline preparation, a preparation method and a usage method thereof. Background Art

[0002] The trioxygen therapy uses autologous blood as a carrier, fuses a certain concentration of trioxygen (O3, ozone), and then injects it into the blood. The medical mechanism of trioxygen is used for the treatment of pain, chronic diseases, and cardiovascular and cerebrovascular diseases. Specifically, after collecting 150-200 ml of the patient's median cubital vein blood according to the patient's weight, it is injected into the blood at a ratio of 1:1 with the pre-set concentration of trioxygen. After mixing for about 3-5 minutes, the blood is fully trioxygenated, and then it is transfused back into the patient's body in about 30 minutes. The treatment is carried out 3-5 times a week or once a day. The specific treatment plan and course of treatment need to be determined according to the specific condition of the patient.

[0003] However, it should be noted that the treatment of trioxygen therapy involves extracorporeal blood operation and needs to be carried out in a sterile environment. The operation is complex, with high requirements and high costs. In addition, to prevent blood coagulation, a certain proportion of anticoagulant (sodium citrate) needs to be added. The absorption rate of the anticoagulant in the human body is very slow, which will have many effects on the human body. Some people will have hematochezia due to platelet problems. During the operation, the mixing of trioxygen and blood needs to be completed manually, and the fusion is not thorough and accurate, which affects the treatment effect. During blood drawing or blood transfusion, patients with weak cardiac function are prone to other symptoms, forming contraindications. Affected by the volume of autologous blood transfusion (usually 150-300 cc each time), the intake of trioxygen is limited, and the treatment effect is correspondingly affected. Some patients have phenomena such as blood faint. Summary of the Invention

[0004] In order to solve the above technical problems, the present invention provides a trioxygenated saline preparation, a preparation method and a usage method thereof.

[0005] The technical solution adopted by the present invention is as follows: A trioxygenated saline preparation, comprising: normal saline, and the normal saline fuses trioxygen to form the preparation.

[0006] The concentration of the trioxygenated saline preparation is 3-6 μg / mL.

[0007] The preparation method of the trioxygenated saline preparation comprises the following steps:

[0008] Using medical oxygen as the gas source, trioxygen gas with a concentration of 70-80 mg / L is prepared by a trioxygen generator;

[0009] The trioxygen gas is then mixed with oxygen in proportion to obtain a mixed gas, the mixed gas;

[0010] Inject the mixed gas into the normal saline bottle at a pressure of 0.2 MPa through a pressure pump, and mix the mixed gas with the normal saline for 3 - 5 minutes to obtain the ozonated normal saline preparation.

[0011] The usage method of the ozonated normal saline preparation includes the following steps: The normal saline preparation is input into the human body by the method of intravenous reinfusion, and the intravenous reinfusion time is 20 min / bottle.

[0012] The beneficial effects of the present invention:

[0013] The ozonated normal saline preparation of the present invention is simple to operate and can be operated under conventional environments; its composition only includes normal saline and ozone, and it will decompose into oxygen and hydrogen peroxide about 15 minutes after entering the human body, without any toxic substances and residues, being simple, green and safe; there are not many taboos in its use, and its applicability is wider; it can be recycled for a long time without phenomena such as drug resistance. Specific embodiments

[0014] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0015] In the prior art, in the major autohemotherapy with ozone, 200 cc of blood is drawn out each time, mixed with ozone and then reinfused into the body. Each time, 10 times are required, totaling 2000 cc, which is about half of the human body's blood volume, and several problems will occur:

[0016] (1) Because a large amount of anticoagulant is added to the reinfused blood, there will be many taboos for the human body;

[0017] (2) During the process of blood drawing and reinfusion, there will be a sense of compression on the heart and blood vessels (a certain pressure is required to mix ozone into the blood), which will cause problems such as palpitation, and in severe cases, it may lead to lesions such as myocardial weakness;

[0018] (3) Since the amount of ozone input is too large, ozone will be converted into oxygen in the human body in about 15 minutes, increasing the blood oxygen concentration; such a large amount of blood replacement will cause the pressure of alveolar oxygen exchange, thus resulting in lung problems.

[0019] Based on the above problems, the present invention proposes an ozonated normal saline preparation. Specifically, the ozonated normal saline preparation includes normal saline, and the normal saline is fused with ozone to form the preparation.

[0020] In an embodiment of the present invention, the concentration of the ozonated normal saline preparation is 3 - 6 μg / m L 。

[0021] The ozonated saline preparation of the present invention utilizes the medical mechanism of ozone to treat pain, chronic diseases, and cardiovascular and cerebrovascular diseases, and can also be used for physical health care, disease prevention, etc.

[0022] Corresponding to the ozonated saline preparation of the above embodiment, the present invention also provides a preparation method of the ozonated saline preparation.

[0023] Specifically, the preparation method of the ozonated saline preparation includes the following steps:

[0024] S1: Using medical oxygen as the gas source, ozone gas with a concentration of 70 - 80 mg / L is prepared by an ozone generator.

[0025] S2: The ozone gas is then mixed with oxygen in proportion to obtain a mixed gas.

[0026] S3: The mixed gas is injected into the saline bottle at a pressure of 0.2 MPa through a pressure pump, and the mixed gas is mixed with the saline for 3 - 5 minutes to obtain the ozonated saline preparation.

[0027] Corresponding to the ozonated saline preparation of the above embodiment, the present invention also provides a usage method of the ozonated saline preparation, including the following steps: The saline preparation is input into the human body by the method of intravenous reinfusion, and the intravenous reinfusion time is 20 min / bottle.

[0028] The ozonated saline preparation, preparation method and usage method of the present invention fully fuse saline with ozone according to the condition of the treated disease, and then are input into the patient's body by the method of intravenous reinfusion in about 20 minutes. The present invention uses "saline" instead of "autologous blood", dissolves a certain concentration of ozone in saline, and then inputs it into the human body, achieving the same therapeutic effect as the existing "major autohemotherapy with ozone", and moreover, avoiding the taboos caused by blood problems and the damage to organs.

[0029] Compared with the "major autohemotherapy with ozone", the present invention also has the following advantages:

[0030] (1) Simple operation, can be operated in a conventional environment;

[0031] (2) Only saline and ozone, about 15 minutes after entering the human body, it will decompose into oxygen and hydrogen peroxide, without any toxic and harmful substances and residues, simple, green and safe;

[0032] (3) Without too many taboos, more widely applicable;

[0033] (4) Can be used in long-term circulation, without phenomena such as drug resistance.

[0034] This specific implementation manner is only an interpretation of the present invention and not a limitation thereof. Any changes made by those skilled in the art after reading the specification of the present invention will be protected by the patent law as long as they are within the scope of the claims of the present invention.

Claims

1. A tri-oxygen physiological saline preparation, characterized in that, Comprising: Normal saline, and the normal saline is fused with ozone to form the preparation.

2. The ozonated saline preparation according to claim 1, characterized in that, The concentration of the ozone saline preparation is 3-6 μg / m L .

3. The preparation method of the ozone physiological saline preparation according to any one of claims 1-2, characterized in that, Comprising the following steps: Using medical oxygen as the gas source, ozone gas with a concentration of 70 - 80 mg / L is prepared by an ozone generator; The ozone gas is then mixed with oxygen in proportion to obtain a mixed gas; The mixed gas is injected into a normal saline bottle through a pressure pump at a pressure of 0.2 MPa, and the mixed gas is mixed with the normal saline for 3 - 5 minutes to obtain an ozone normal saline preparation.

4. The method for using the ozone physiological saline preparation according to claim 1, characterized in that, The normal saline preparation is input into the human body by the intravenous return method, and the intravenous return time is 20 min / bottle.