Children cough-relieving oral liquid containing dandelion component and preparation method of children cough-relieving oral liquid

Abstract

The invention relates to a children cough-relieving oral liquid containing a dandelion component and a preparation method thereof. The children cough-relieving oral liquid containing the dandelion component is prepared from 400 to 720 parts of radix scutellariae, 300 to 600 parts of fructus forsythiae, 100 to 180 parts of rhizoma nelumbinis, 30 to 120 parts of radix rehmanniae, 200 to 500 parts of dandelion, 80 to 250 parts of radix paeoniae rubra, 20 to 120 parts of mint, 100 to 180 parts of pollen typhae, 10 to 15 parts of aspongopus, 80 to 250 parts of pollen typhae, 20 to 120 parts of honeysuckle flower, 20 to 120 parts of candied date and 40 to 60 parts of lily bulb. According to the invention, different medicinal materials are extracted by adopting modes of high-pressure stirring, high-temperature decoction, grinding and the like, the effective content in the extracted oral liquid is higher, and the effect is good after the oral liquid is taken; the dandelion component contained in the oral liquid can effectively clear away heat and toxic materials and reduce swelling and remove stasis; the candied dates and the lilies are sweet in taste, so that the medicine taking compliance of children can be improved.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine preparations, and particularly relates to a pediatric cough-relieving oral liquid containing dandelion components and a preparation method thereof. Background Art

[0002] Pediatric Qingre Zhike Oral Liquid is a traditional Chinese medicine preparation, which has the effects of clearing heat and dispersing lung qi, relieving asthma, and relieving sore throat. It is widely used for patients with symptoms such as fever and aversion to cold caused by exogenous wind-heat in children, cough with profuse sputum, shortness of breath and wheezing, dry mouth and hoarseness, and sore throat. However, due to the limitations of the early process level, the production process of this product is only a simple water extraction process.

[0003] However, for Qingre Zhike Oral Liquid, the content of effective components is small, the taking effect is not good, and the taste of the oral liquid is bitter, so the compliance of children taking it is not good. Summary of the Invention

[0004] The purpose of the present invention is to propose a pediatric cough-relieving oral liquid containing dandelion components and a preparation method thereof in order to solve the above problems.

[0005] In order to achieve the above purpose, the present invention adopts the following technical solutions: A pediatric cough-relieving oral liquid containing dandelion components, the oral liquid is composed of 400 - 720 parts of Scutellaria baicalensis, 300 - 600 parts of Forsythia suspensa, 100 - 180 parts of lotus rhizome nodes, 30 - 120 parts of Rehmannia glutinosa, 200 - 500 parts of dandelion, 80 - 250 parts of Paeonia lactiflora, 20 - 120 parts of Mentha haplocalyx, 100 - 180 parts of Typha angustifolia, 10 - 15 parts of Aspongopus chinensis, 80 - 250 parts of Typha angustifolia, 20 - 120 parts of Lonicera japonica, 20 - 120 parts of honey dates, and 40 - 60 parts of Lilium brownii.

[0006] The preparation method of the pediatric cough-relieving oral liquid containing dandelion components includes the following steps: Step 1, preparation of decocted liquid: Take 30 - 120 parts of Rehmannia glutinosa, 200 - 500 parts of dandelion, 80 - 250 parts of Paeonia lactiflora, and 20 - 120 parts of Mentha haplocalyx, wash the surface impurities with distilled water, then place them in container A, add 10 times the amount of distilled water, boil the water until the water volume is reduced to two-thirds of the original volume, then let it stand for 2 minutes, then filter the residue from the liquid in container A and pour it out and collect it in container B. Then add 10 times the amount of distilled water to container A again, boil the water until the water volume is reduced to two-thirds of the original volume, then let it stand for 2 minutes, then filter the residue from the liquid in container A and pour it out and collect it in container B to obtain the decocted liquid; Step 2, preparation of medicinal powder: Take 10-15 parts of Coridius chinensis, 100-180 parts of lotus rhizome nodes and 20-120 parts of honeysuckle flower. Wash the surface impurities with distilled water, then place them in a crusher to break them up, and then take them out after drying in a dry environment at 35-45 °C for 72-96 hours. Next, use a rolling roller to squeeze repeatedly until the mixture of Coridius chinensis, lotus rhizome nodes and honeysuckle flower becomes powdery, thus obtaining medicinal powder; Step 3, preparation of the extract: Take 400-720 parts of Scutellaria baicalensis, 300-600 parts of Forsythia suspensa, 100-180 parts of Typha angustifolia pollen, 80-250 parts of Typha angustifolia pollen. Wash the surface impurities with distilled water, then place them in a high-pressure tank with a material-liquid ratio of 1:25 and a pressure of 300-500 MPa, stir for 30-50 min, and then pour out the internal mixture and filter out the impurities to obtain the extract; Step 4, obtaining the compound oral liquid of dandelion extract: Mix and stir the decocted liquid, medicinal powder and extract for 2-4 min to obtain a mixed medicinal liquid.

[0007] Add the mixed medicinal liquid to 95% ethanol and stir. After refrigerating for 48 h, filter it with a microporous filter to obtain the compound oral liquid of dandelion extract.

[0008] The compound oral liquid of dandelion extract needs to be quantified with purified water, add 0.2% preservative, adjust the pH value to 6.5-7.0, seal it, and sterilize it.

[0009] In summary, due to the adoption of the above technical solutions, the beneficial effects of the present invention are: By extracting different medicinal materials by means of high-pressure stirring, high-temperature decocting and powder grinding, the effective content in the extracted oral liquid is higher, and the effect after taking the medicine is good; and the dandelion component contained in the oral liquid can effectively clear heat and detoxify, disperse swelling and dissipate binds; while the jujube and lily components are sweet, which can increase the compliance of children taking medicine. Specific embodiments

[0010] A compound oral liquid for relieving cough in children containing dandelion components according to the present invention, the oral liquid is composed of 400-720 parts of Scutellaria baicalensis, 300-600 parts of Forsythia suspensa, 100-180 parts of lotus rhizome nodes, 30-120 parts of Rehmannia glutinosa, 200-500 parts of dandelion, 80-250 parts of Paeonia lactiflora, 20-120 parts of Mentha haplocalyx, 100-180 parts of Typha angustifolia pollen, 10-15 parts of Coridius chinensis, 80-250 parts of Typha angustifolia pollen, 20-120 parts of honeysuckle flower, 20-120 parts of jujube and 40-60 parts of lily.

[0011] The preparation method of the compound oral liquid for relieving cough in children containing dandelion components comprises the following steps: Step 1, preparation of the decocted liquid: Take 30 - 120 parts of Rehmanniae Radix, 200 - 500 parts of Taraxaci Herba, 80 - 250 parts of Paeoniae Radix Rubra, and 20 - 120 parts of Menthae Herba. Wash the surface impurities with distilled water, then place them in Container A and add 10 times the amount of distilled water. Boil the decoction until the water volume is reduced to two-thirds of the original, then let it stand for 2 minutes. Then filter the residue from the liquid in Container A and pour out the filtrate into Container B. Next, add 10 times the amount of distilled water to Container A again, boil the decoction until the water volume is reduced to two-thirds of the original, then let it stand for 2 minutes. Then filter the residue from the liquid in Container A and pour out the filtrate into Container B to obtain the decocted liquid; Step 2, Preparation of medicinal powder: Take 10 - 15 parts of Aspongopus, 100 - 180 parts of Nelumbinis Rhizomatis Nodus, and 20 - 120 parts of Lonicerae Japonicae Flos. Wash the surface impurities with distilled water, then place them in a pulverizer to break them up, and then take them out after drying in a 35 - 45°C environment for 72 - 96 hours. Then repeatedly squeeze them with a rolling roller until the mixture of Aspongopus, Nelumbinis Rhizomatis Nodus, and Lonicerae Japonicae Flos becomes powdery to obtain the medicinal powder; Step 3, Preparation of extract: Take 400 - 720 parts of Scutellariae Radix, 300 - 600 parts of Forsythiae Fructus, 100 - 180 parts of Typhae Pollen, 80 - 250 parts of Typhae Pollen. Wash the surface impurities with distilled water, then place them in a high-pressure tank with a material-liquid ratio of 1:25 and a pressure of 300 - 500 MPa. Stir for 30 - 50 minutes and then pour out the internal mixed liquid and filter off the impurities to obtain the extract; Step 4, Obtaining the compound oral liquid of dandelion extract: Mix and stir the decocted liquid, medicinal powder, and extract for 2 - 4 minutes to obtain the mixed medicinal liquid.

[0012] Add the mixed medicinal liquid to 95% ethanol and stir. After refrigerating for 48 hours, filter it with a microfiltration filter to obtain the compound oral liquid of dandelion extract.

[0013] The compound oral liquid of dandelion extract needs to be quantified with purified water, add 0.2% preservative, adjust the pH value to 6.5 - 7.0, seal, and sterilize.

Claims

1. A pediatric cough-relieving oral liquid containing dandelion ingredients, characterized in that, The oral liquid is composed of 400 - 720 parts of Scutellaria baicalensis, 300 - 600 parts of Forsythia suspensa, 100 - 180 parts of lotus rhizome node, 30 - 120 parts of Rehmannia glutinosa, 200 - 500 parts of Taraxacum mongolicum, 80 - 250 parts of Paeonia lactiflora, 20 - 120 parts of Mentha haplocalyx, 100 - 180 parts of Typha angustifolia pollen, 10 - 15 parts of Coridius chinensis, 80 - 250 parts of Typha angustifolia pollen, 20 - 120 parts of Lonicera japonica, 20 - 120 parts of candied date, and 40 - 60 parts of Lilium brownii.

2. The preparation method of a pediatric cough-relieving oral liquid containing dandelion components as described in claim 1, characterized in that, It includes the following steps: Step 1, preparation of decocted liquid: Take 30 - 120 parts of Rehmannia glutinosa, 200 - 500 parts of Taraxacum mongolicum, 80 - 250 parts of Paeonia lactiflora, and 20 - 120 parts of Mentha haplocalyx, wash the surface impurities with distilled water, then place them in container A, add 10 times the amount of distilled water, boil the decoction until the water volume is reduced to two-thirds of the original, then let it stand for 2 min, and then filter the residue from the liquid in container A and pour it out and collect it in container B. Then add 10 times the amount of distilled water to container A again, boil the decoction until the water volume is reduced to two-thirds of the original, then let it stand for 2 min, and then filter the residue from the liquid in container A and pour it out and collect it in container B to obtain the decocted liquid. Step 2, preparation of medicinal powder: Take 10 - 15 parts of Coridius chinensis, 100 - 180 parts of lotus rhizome node, and 20 - 120 parts of Lonicera japonica, wash the surface impurities with distilled water, then place them in a pulverizer to break them up, and then put them in a drying environment at 35 - 45 °C for 72 - 96 hours and take them out. Then use a rolling roller to squeeze repeatedly until the mixture of Coridius chinensis, lotus rhizome node, and Lonicera japonica is in the form of flour to obtain the medicinal powder. Step 3, preparation of extract: Take 400 - 720 parts of Scutellaria baicalensis, 300 - 600 parts of Forsythia suspensa, 100 - 180 parts of Typha angustifolia pollen, 80 - 250 parts of Typha angustifolia pollen, wash the surface impurities with distilled water, then place them in a high-pressure tank with a material-liquid ratio of 1:25 and a pressure of 300 - 500 MPa, stir for 30 - 50 min, and then pour out the internal mixed liquid and filter out the impurities to obtain the extract. Step 4, obtaining the compound oral liquid of dandelion extract: Mix and stir the decocted liquid, medicinal powder, and extract for 2 - 4 min to obtain a mixed medicinal liquid.

3. Add the mixed medicinal liquid to 95% ethanol and stir, refrigerate for 48 h, and then filter with a microporous filter to obtain the compound oral liquid of dandelion extract.

4. The preparation method of a pediatric cough-relieving oral liquid containing dandelion components according to claim 2, characterized in that, The compound oral liquid of dandelion extract needs to be quantitatively determined with purified water, add 2% preservative, adjust the pH value to 5 - 0, seal, and sterilize.