Traditional Chinese medicine composition for relieving cough and preparation method thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicine compositions, and provides a traditional Chinese medicine composition for relieving cough to solve the problems that an existing cough medicine is single in curative effect, poor in taste, inconvenient to take and complex in component. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 25 parts of adenophora stricta, 10 parts of honey ephedra, 7.5 parts of bistort rhizome, 14 parts of shellac, 5 parts of liquorice and 10 parts of honey. The invention also provides a preparation method of the traditional Chinese medicine composition, which comprises the following steps: step 1, respectively weighing the raw materials in parts by weight for later use; step 2, adding the weighed adenophora stricta, liquorice, bistort rhizome, shellac and honey-fried ephedra into water, soaking for 12 hours, then decocting twice, combining decocted liquid medicine, standing and precipitating for 12 hours, and filtering to obtain filtered liquid medicine; and step 3, concentrating the filtered liquid medicine, adding the weighed honey, continuing to decoct, and subpackaging to obtain the traditional Chinese medicine composition.

Description

Technical Field

[0001] The present invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for relieving cough and a preparation method thereof. Background Art

[0002] Cough is a common symptom of respiratory diseases. Traditional Chinese medicine (Mongolian medicine) believes that cough is mostly caused by exogenous wind-cold, wind-heat or internal injury of lung yin. As a traditional Chinese medicinal material (Mongolian medicine), Adenophora stricta has the effects of nourishing yin and clearing the lung, resolving phlegm and relieving cough, and is commonly used to treat dry cough due to lung heat, chronic cough due to yin deficiency, etc.

[0003] At present, there are already various traditional Chinese medicine (Mongolian medicine) preparations for relieving cough on the market, such as water pills, powders, syrups, oral liquids, granules, etc., but there are still the following deficiencies: (1) Single curative effect: Existing cough-relieving drugs mostly target specific types of cough, such as wind-cold cough or wind-heat cough, lacking universality for multiple cough types; (2) Poor taste: Some cough-relieving drugs contain bitter or irritating components, resulting in a poor taking experience for patients, especially low compliance among child patients; (3) Inconvenient to take: Traditional decoctions are cumbersome to decoct and inconvenient to carry; some patent medicines have a large volume and it is not easy to control the dosage; (4) Complex components: Some cough-relieving drugs have complex components, and there may be potential drug interactions or adverse reactions. Summary of the Invention

[0004] The purpose of the present invention is to overcome the deficiencies of the prior art and provide a traditional Chinese medicine composition for relieving cough with definite curative effect, suitable taste, convenient taking and high safety, and a preparation method thereof.

[0005] The first object of the present invention is to provide a traditional Chinese medicine composition for relieving cough, which is made from the following raw materials in parts by weight: 25 - 50 parts of Adenophora stricta, 10 - 20 parts of honey-fried Ephedra, 7.5 - 15 parts of Bistorta officinalis, 14 - 28 parts of Gummi Arcae, 5 - 10 parts of Glycyrrhiza uralensis, 10 - 20 parts of honey.

[0006] The formula of the traditional Chinese medicine composition of the present invention is cool in nature, and is a formula with the functions of clearing lung heat and relieving cough and coordinated functions. In the present invention, Adenophora stricta and Glycyrrhiza uralensis are sweet in taste, Bistorta officinalis and Gummi Arcae are bitter in taste, and Ephedra is pungent and slightly bitter. The sweet taste tonifies the lung and relieves asthma, and the bitter taste has the effect of clearing heat. With Adenophora stricta, which has the functions of clearing lung heat and relieving cough, as the main drug, Bistorta officinalis, Ephedra and Glycyrrhiza uralensis, which have the functions of clearing blood heat and relieving cough and resolving phlegm, as the adjuvant drugs, and Gummi Arcae, which has the function of clearing blood heat, as the assistant and guiding drug, the present invention has a good curative effect on lung heat diseases and various febrile coughs.

[0007] Preferably, the traditional Chinese medicine composition for relieving cough is made from the following raw materials in parts by weight: 25 parts of Adenophora stricta, 10 parts of honey-fried Ephedra, 7.5 parts of Bistorta officinalis, 14 parts of Gummi Arcae, 5 parts of Glycyrrhiza uralensis, and 10 parts of honey.

[0008] Preferably, the traditional Chinese medicine composition is an ointment.

[0009] In the traditional Chinese medicine composition of the present invention, Adenophora stricta, honey-fried Ephedra, and Bistorta officinalis have the effect of nourishing yin and moistening the lungs, Gummi Arcae and Glycyrrhiza uralensis have the effect of clearing heat and detoxifying, and honey can regulate the properties of the medicine and enhance the medicinal effect.

[0010] The second object of the present invention is to provide a preparation method of the above-mentioned traditional Chinese medicine composition for relieving cough, which includes the following steps: Step 1: Weigh 25 - 50 parts of Adenophora stricta, 10 - 20 parts of honey-fried Ephedra, 7.5 - 15 parts of Bistorta officinalis, 14 - 28 parts of Gummi Arcae, 5 - 10 parts of Glycyrrhiza uralensis, and 10 - 20 parts of honey respectively according to parts by weight, and set aside; Step 2: Add water to the weighed Adenophora stricta, Glycyrrhiza uralensis, Bistorta officinalis, Gummi Arcae, and honey-fried Ephedra, soak for 12 hours, then conduct decoction twice. Combine the decoction liquid, let it stand and precipitate for 12 hours, and filter to obtain the filtered decoction liquid; Step 3: Concentrate the filtered decoction liquid. When the relative density reaches 1.05, collect the concentrated liquid into a paste. After the concentrated liquid is boiled until it forms a flag, add the weighed honey, continue to boil until it forms a flag, then subpackage to obtain the traditional Chinese medicine composition.

[0011] Preferably, in Step 2, the amount of water added for each decoction is 8 - 10 times the total weight of each medicinal material.

[0012] Preferably, in Step 2, the decoction conditions are: after the decoction temperature reaches 100°C, decoct for another 90 minutes.

[0013] Preferably, in Step 2, the mesh number of the filter is 160 - 200 meshes.

[0014] Preferably, the sealing temperature for subpackaging is 120°C, and the filling volume is 11 milliliters.

[0015] Compared with the prior art, the beneficial effects of the present invention are as follows: (1)Simplified formula: The present invention takes Adenophora as the main ingredient and is combined with other traditional Chinese medicines (Mongolian medicines) with synergistic effects. The formula is simplified and not only has the effect of relieving cough, but also nourishes yin and moistens the lungs, improves lung function, enhances immunity, and has an overall conditioning effect. The medicinal formula provided by the present invention is cool in nature and is a formula with synergistic functions of clearing lung heat and relieving cough. In the present invention, Glehnia littoralis and Glycyrrhiza glabra are sweet in taste, Bistorta officinalis and Erythrina indica are bitter in taste, and Ephedra sinica is pungent and slightly bitter. The sweet taste tonifies the lung and relieves asthma, and the bitter taste has a heat-clearing effect. With Glehnia littoralis, which has the functions of clearing lung heat and relieving cough, as the main medicine, Bistorta officinalis, honey-fried Ephedra, and Glycyrrhiza glabra, which have the functions of clearing blood heat and relieving cough and reducing phlegm, as auxiliary medicines, and Erythrina indica, which has the function of clearing blood heat, as the assistant and guiding medicine, the traditional Chinese medicine composition provided by the present invention has good curative effects on lung heat diseases and various coughs.

[0016] (2)The traditional Chinese medicine composition of the present invention is applicable to clearing lung heat, relieving cough, cough after infection, chronic bronchitis, etc., and has a particularly significant effect on patients with persistent cough. (3)Suitable taste: The present invention uses auxiliary materials such as honey to adjust the taste, which is easy for patients to accept and improves the compliance of taking medicine. (4)Dosage form innovation: The present invention improves the traditional decoction into an ointment, which is convenient to carry and take, and the dosage is easy to control.

[0017] (5)High safety: The present invention selects traditional Chinese medicines (Mongolian medicines) that are both edible and medicinal. The ingredients are natural. Compared with chemical drugs, they have high safety, small side effects, and are suitable for long-term use. Description of the Drawings

[0018] Figure 1 It is a flowchart of the preparation method of the traditional Chinese medicine composition for relieving cough provided by the embodiment of the present invention. Detailed Embodiments

[0019] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention. Embodiment 1

[0020] The embodiment of the present invention provides a traditional Chinese medicine composition for relieving cough, which is made from the following raw materials in parts by weight: 25 parts of Adenophora, 10 parts of honey-fried Ephedra, 7.5 parts of Bistorta officinalis, 14 parts of Erythrina indica, 5 parts of Glycyrrhiza glabra, and 10 parts of honey.

[0021] In the embodiment of the present invention, the traditional Chinese medicine composition is an ointment.

[0022] As Figure 1As shown in the figure, an embodiment of the present invention further provides a preparation method of the above-mentioned traditional Chinese medicine composition for relieving cough, comprising the following steps: Step 1: Weigh 25 parts of Adenophora stricta, 10 parts of honey-fried Ephedra, 7.5 parts of Bistorta officinalis, 14 parts of Gummi Arcae, 5 parts of Glycyrrhiza uralensis, and 10 parts of honey respectively by weight, and set aside; Step 2: Add the weighed Adenophora stricta, Glycyrrhiza uralensis, Bistorta officinalis, Gummi Arcae, and honey-fried Ephedra to water and soak for 12 hours, then conduct decoction. When the decoction temperature reaches 100 °C, decoct for another 90 minutes. Decoct twice, and the amount of water added for both decoctions is 8 times the total weight of each medicinal material. After both decoctions are completed, combine the decoction liquid, let it stand and precipitate for 12 hours, filter, and the filtering mesh size is 180 meshes to obtain the filtered liquid; Step 3: Concentrate the filtered liquid under -0.07 mp until the relative density reaches 1.05, transfer the concentrated liquid to a container for collecting paste to collect the paste. When the concentrated liquid boils and forms a flag, add the weighed honey, continue to boil until the relative density reaches 1.15 - 1.2, then sub-pack, the sealing temperature for sub-packaging is 120 °C, and the filling volume is 10 ml to obtain the traditional Chinese medicine composition.

[0023] The usage method of the traditional Chinese medicine composition in the embodiment of the present invention is as follows: Oral administration: 1 - 2 times a day, 10 grams each time, taken with warm water. Example 2

[0024] An embodiment of the present invention provides a traditional Chinese medicine composition for relieving cough, which is made from the following raw materials by weight: 40 parts of Adenophora stricta, 15 parts of honey-fried Ephedra, 10 parts of Bistorta officinalis, 28 parts of Gummi Arcae, 8 parts of Glycyrrhiza uralensis, and 15 parts of honey.

[0025] In the embodiment of the present invention, the traditional Chinese medicine composition is an ointment.

[0026] An embodiment of the present invention further provides a preparation method of the above-mentioned traditional Chinese medicine composition for relieving cough, comprising the following steps: Step 1: Weigh 40 parts of Adenophora stricta, 15 parts of honey-fried Ephedra, 10 parts of Bistorta officinalis, 28 parts of Gummi Arcae, 8 parts of Glycyrrhiza uralensis, and 15 parts of honey respectively by weight, and set aside; Step 2: Add the weighed Adenophora stricta, Glycyrrhiza uralensis, Bistorta officinalis, Gummi Arcae, and honey-fried Ephedra to water and soak for 12 hours, then conduct decoction. When the decoction temperature reaches 100 °C, decoct for another 90 minutes. Decoct twice, and the amount of water added for both decoctions is 9 times the total weight of each medicinal material. After both decoctions are completed, combine the decoction liquid, let it stand and precipitate for 12 hours, filter, and the filtering mesh size is 160 meshes to obtain the filtered liquid; Step 3: Concentrate the filtered medicinal liquid at -0.07 mp. When the relative density reaches 1.05, transfer the concentrated liquid to a container for collecting the extract and collect the extract. After the concentrated liquid is boiled until it forms a flag, add the weighed honey and continue boiling until the relative density reaches 1.15 - 1.2. Then, carry out sub-packaging. The sealing temperature for sub-packaging is 120 °C and the filling volume is 10 ml, thus obtaining the traditional Chinese medicine composition.

[0027] The usage method of the traditional Chinese medicine composition in the embodiment of the present invention is as follows: Oral administration: 1 - 2 times a day, 10 grams each time, taken with warm water. Example 3

[0028] The embodiment of the present invention provides a traditional Chinese medicine composition for relieving cough, which is made from the following raw materials in parts by weight: Glehnia littoralis 50 parts, honey-fried Ephedra 20 parts, Bistorta officinalis 15 parts, Butea monosperma 20 parts, Glycyrrhiza uralensis 10 parts, honey 20 parts.

[0029] In the embodiment of the present invention, the traditional Chinese medicine composition is an extract.

[0030] The embodiment of the present invention also provides a preparation method of the above-mentioned traditional Chinese medicine composition for relieving cough, which includes the following steps: Step 1: Weigh 50 parts of Glehnia littoralis, 20 parts of honey-fried Ephedra, 15 parts of Bistorta officinalis, 20 parts of Butea monosperma, 10 parts of Glycyrrhiza uralensis, and 20 parts of honey respectively according to the parts by weight, and set aside; Step 2: Add water to the weighed Glehnia littoralis, Glycyrrhiza uralensis, Bistorta officinalis, Butea monosperma, and honey-fried Ephedra, and soak for 12 hours. Then, carry out decoction. When the decoction temperature reaches 100 °C, decoct for another 90 minutes. Decoct twice. The amount of water added for both decoctions is 10 times the total weight of each medicinal material. After both decoctions are completed, combine the decocted medicinal liquids, let them stand and precipitate for 12 hours, and filter. The mesh number of the filter is 200 meshes, thus obtaining the filtered medicinal liquid; Step 3: Concentrate the filtered medicinal liquid at -0.07 mp. When the relative density reaches 1.05, transfer the concentrated liquid to a container for collecting the extract and collect the extract. After the concentrated liquid is boiled until it forms a flag, add the weighed honey and continue boiling until the relative density reaches 1.15 - 1.2. Then, carry out sub-packaging. The sealing temperature for sub-packaging is 120 °C and the filling volume is 10 ml, thus obtaining the traditional Chinese medicine composition.

[0031] The usage method of the traditional Chinese medicine composition in the embodiment of the present invention is as follows: Oral administration: 1 - 2 times a day, 10 grams each time, taken with warm water.

[0032] Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and purposes of the present invention. The scope of the present invention is defined by the claims and their equivalents.

Claims

1. A traditional Chinese medicine composition for relieving cough, characterized in that, It is made from the following raw materials in parts by weight: Glehnia Root 25 - 50 parts, Honey-fried Ephedra 10 - 20 parts, Bistort Rhizome 7.5 - 15 parts, Lacca 14 - 28 parts, Licorice Root 5 - 10 parts, Honey 10 - 20 parts.

2. The traditional Chinese medicine composition for relieving cough according to claim 1, characterized in that It is made from the following raw materials in parts by weight: Glehnia Root 25 parts, Honey-fried Ephedra 10 parts, Bistort Rhizome 7.5 parts, Lacca 14 parts, Licorice Root 5 parts, Honey 10 parts.

3. The traditional Chinese medicine composition for relieving cough according to claim 1 or 2, characterized in that, The traditional Chinese medicine composition is an ointment.

4. A method for preparing a traditional Chinese medicine composition for relieving cough according to any one of claims 1 to 3, characterized in that, It includes the following steps: Step 1: Weigh Glehnia Root 25 - 50 parts, Honey-fried Ephedra 10 - 20 parts, Bistort Rhizome 7.5 - 15 parts, Lacca 14 - 28 parts, Licorice Root 5 - 10 parts, Honey 10 - 20 parts respectively according to the weight parts for standby; Step 2: Add water to the weighed Glehnia Root, Licorice Root, Bistort Rhizome, Lacca, and Honey-fried Ephedra, soak for 6 - 18 hours, then conduct decoction. Decoct twice, combine the decoction liquid, let it stand and precipitate for 6 - 18 hours, and filter to obtain the filtered decoction liquid; Step 3: Concentrate the filtered decoction liquid. When the relative density reaches 1.05, collect the concentrated liquid into a paste. After the concentrated liquid is boiled until it forms a flag, add the weighed honey, continue to boil until it forms a flag, then subpackage to obtain the traditional Chinese medicine composition.

5. The preparation method of the traditional Chinese medicine composition for relieving cough according to claim 4, characterized in that, In Step 2, the amount of water added for each decoction is 8 - 10 times the total weight of each medicinal material.

6. The preparation method of the traditional Chinese medicine composition for relieving cough according to claim 3, characterized in that, In Step 2, the decoction conditions are: after the decoction temperature reaches 100 °C, decoct for another 90 minutes.

7. The preparation method of the traditional Chinese medicine composition for relieving cough according to claim 3, characterized in that, In Step 2, the mesh number for filtration is 160 - 200 meshes.

8. The preparation method of the traditional Chinese medicine composition for relieving cough according to claim 3, characterized in that, The sealing temperature for subpackaging is 120 °C, and the filling volume is 10 ml.

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