Punching and discharging structure of microneedle patch punching, roller cutting, waste tearing and pasting all-in-one machine

Abstract

The invention provides a punching and discharging structure of a microneedle patch punching, roller cutting, waste tearing and pasting all-in-one machine, and belongs to the technical field of punching all-in-one machines. The micro-needle patch processing equipment solves the problem that the rate of finished products becomes low when existing micro-needle patch processing equipment is used for processing small micro-needle patches for a long time. According to the punching and discharging structure of the micro-needle patch punching, roll cutting, waste tearing and pasting all-in-one machine, the micro-needle patch punching, roll cutting, waste tearing and pasting all-in-one machine comprises a rack, a cutting roll tool apron which is arranged on the rack and can conduct roll cutting on a composite film, and a soluble micro-needle patch pasting and discharging table which is arranged on the rack and located behind the cutting roll tool apron. The punching and blanking structure comprises a truss manipulator which is connected to the rack in a sliding mode in the left-right direction and can transfer the soluble microneedle sheets to the composite film to press the composite film down to the blanking disc. According to the punching and blanking structure of the microneedle patch punching, roller cutting, waste tearing and pasting all-in-one machine, the pasting stability can be guaranteed, rapid blanking can be achieved, blanking and demolding are convenient, and the yield of products is also improved.

Description

Technical Field

[0001] The present invention belongs to the technical field of punching and cutting integrated machines, and relates to a punching and blanking structure of a micro-needle patch punching, rolling, waste tearing and pasting integrated machine. Background Art

[0002] As Figure 1 shown, a micro-needle patch is formed by punching a soluble micro-needle original sheet. When punching, a relatively large soluble micro-needle original sheet is usually cut multiple times into corresponding shapes to form a soluble micro-needle sheet 1 that can be sucked. At the same time, the composite film 2 is roll-cut. After cutting, a paste sheet 3 with a corresponding shape is connected to the composite film 2. The inner edge of the paste sheet 3 has an inner bonding surface 31. The punching table cuts the soluble micro-needle original sheet 4. After cutting, the soluble micro-needle original sheet 4 forms multiple groups of soluble micro-needle sheets 1. The manipulator places the cut soluble micro-needle sheets 1 on the paste sheet 3. The soluble micro-needle sheets 1 are attached to the exposed inner bonding surface 31 of the inner edge of the paste sheet 3 to form a micro-needle patch.

[0003] The existing punching, rolling, waste tearing and pasting integrated machine, such as the one disclosed in Chinese Patent Application [Publication No.: CN119550431A], discloses a punching, rolling, waste tearing and pasting integrated machine for micro-needle patches, which includes a frame. A cutting roller knife seat is provided on the frame. A bottom roller and a cutting roller are rotatably connected to the cutting roller knife seat. The composite film can pass between the bottom roller and the cutting roller and is cut by it. The cutting roller has multiple groups of roller blade groups arranged along the circumferential direction of the cutting roller and multiple pairs of connecting roller knives arranged along the circumferential direction of the cutting roller. Each group of roller blade groups includes a kidney-shaped roller blade one, roller blade two, and roller blade three. The roller blade one of the same group is located inside the roller blade two, and the roller blade two of the same group is located inside the roller blade three. Openings are provided at both ends of the roller blade two. The end parts of the connecting roller knives connect the wall surfaces of the openings of the roller blade two in adjacent groups of roller blade groups. The middle part of the connecting roller knife intersects with the corresponding roller blade three. A reserved notch is provided on the cutting edge of the roller blade three at the intersection with the connecting roller knife. The edge height of the roller blade two is lower than the edge heights of the roller blade one and the roller blade three. A truss manipulator is connected to the frame and can grab and move the soluble micro-needle sheet to the kidney-shaped sheet. Support rollers that can horizontally tension the cut composite film are fixedly connected to the front and rear ends of the soluble micro-needle sheet pasting and blanking table. A blanking disk that can suck the kidney-shaped sheet is also hinged inside the soluble micro-needle sheet pasting and blanking table. The truss manipulator can push the soluble micro-needle sheet to drive the kidney-shaped sheet to move downward and press on the blanking disk.

[0004] The soluble microneedle sheet in the above structure is grasped by a gantry robot. After grasping, it is moved by the gantry robot to the composite film after cutting on the soluble microneedle sheet pasting and blanking table. The composite film is tensioned by a tensioning roller. The gantry robot presses the composite film on the blanking tray and moves synchronously with the blanking tray to realize the demolding of the microneedle patch pasted on the composite film. However, since the composite film is only tensioned by the tensioning roller, the tensioning effect of the composite film on the blanking tray is poor during the gradual downward movement, making it difficult to pull out the microneedle patch from the composite film, resulting in some microneedle patches being unable to separate from the composite film, thereby affecting the yield of the formed product, reducing the production efficiency and blanking efficiency, and the composite film is prone to displacement deviation during the continuous pulling process when moving downward, reducing the yield of the microneedle patch. Summary of the Invention

[0005] The object of the present invention is to address the above problems existing in the prior art and propose a punching and blanking structure for a microneedle patch punching, roller cutting, waste tearing and pasting integrated machine. The technical problem to be solved by the present invention is: how to solve the problem that the yield of the existing microneedle patch processing equipment becomes low during the long-term processing of relatively small microneedle patches.

[0006] The object of the present invention can be achieved by the following technical solutions:

[0007] A punching and blanking structure for a microneedle patch punching, roller cutting, waste tearing and pasting integrated machine. The microneedle patch punching, roller cutting, waste tearing and pasting integrated machine includes a frame, a cutting roller knife seat arranged on the frame and capable of roller cutting the composite film, and a soluble microneedle sheet pasting and blanking table arranged on the frame and located behind the cutting roller knife seat. This punching and blanking structure includes a gantry robot slidably connected to the frame in the left-right direction and capable of moving the soluble microneedle sheet to the composite film and pressing the composite film onto the blanking tray. The gantry robot is located on one side of the soluble microneedle sheet pasting and blanking table. The soluble microneedle sheet pasting and blanking table includes two support plates arranged opposite to each other in the left-right direction. A plurality of tensioning rollers capable of tensioning the cut composite film are connected to the support plates. An articulated shaft is rotatably connected between the two support plates. A blanking tray capable of moving up and down relative to the articulated shaft is connected to the articulated shaft. It is characterized in that a plurality of positioning strips are fixedly connected to the upper ends of the support plates. Positioning grooves corresponding to the positioning strips one by one are formed on the blanking tray. The positioning strips are inserted into the corresponding positioning grooves and can slide relative to the groove walls of the positioning grooves. The top surface of the positioning strip is lower than the highest point of the tensioning roller and can be higher than the upper end surface of the blanking tray. The positioning strips are arranged at intervals in the front-rear direction. The gantry robot has a downwardly protruding suction cup, and when the gantry robot presses down, the suction cup can be inserted between two adjacent positioning strips.

[0008] During production, first, the composite film is roll-cut by a cutting roller knife holder. The cutting roller knife holder, like the one in the above-mentioned comparative document, realizes the cutting of the composite film through the cooperation of a bottom roller and a cutting roller. After cutting, the composite film is tensioned by the tensioning roller of the soluble microneedle sheet pasting blanking table. Then, the truss manipulator moves the cut soluble microneedle sheet onto the cut composite film and presses the composite film against the blanking plate. After pressing, the truss manipulator and the blanking plate move downward synchronously until the positioning strip disengages from the positioning groove. At this time, the soluble microneedle sheet fits with the adhesive patch on the composite film and then separates from the composite film, realizing the rapid blanking of the microneedle patch. By setting the top surface of the positioning strip below the highest point of the tensioning roller, and when the blanking plate gradually moves downward, the top surface of the positioning strip is higher than the upper end surface of the blanking plate, and the positioning strips are distributed at intervals in the front-back direction. The truss manipulator has a downward-protruding suction cup that can adsorb the soluble microneedle sheet. When the truss manipulator presses down, the suction cup can be embedded between two adjacent positioning strips. Therefore, the positioning strip has a resistance to push the composite film upward, while the truss manipulator and the blanking plate have a downward thrust on the composite film. Under the combined action of the two, the microneedle patch well-fitted on the composite film can quickly detach from the composite film, facilitating the blanking of the microneedle patch. After the microneedle patch detaches from the composite film and is placed on the blanking plate, the truss manipulator is moved upward, and the blanking plate rotates along the hinge axis, so that the microneedle patch can quickly slide out of the blanking plate, realizing blanking.

[0009] In this application, by setting a positioning strip, when the blanking plate moves downward, the cooperation between the positioning strip and the positioning groove on the blanking plate realizes the guiding of the blanking plate, ensuring that the truss manipulator can stably paste the soluble microneedle sheet on the corresponding adhesive patch. Since it takes time to press it during the pasting process, in order to avoid displacement deviation during the pressing process, the positioning strip ensures the stability of the up-and-down movement of the blanking plate. During the gradual downward movement, although there is a tensioning roller to tension the composite film, the area of the composite film above the blanking plate is relatively large. Therefore, the positioning strip can also provide a resistance to prevent the composite film from moving downward, helping the microneedle patch to fall off from the composite film, thus ensuring both the stability of pasting and realizing rapid blanking, improving the convenience of blanking and demoulding, and also increasing the product yield.

[0010] A blanking rotary cylinder is connected to one of the support plates, and the motor shaft of the blanking rotary cylinder is fixedly connected to one end of the hinge axis and drives the hinge axis to rotate.

[0011] In the blanking and cutting structure of the above-mentioned microneedle patch punching, rolling, cutting, tearing, and pasting integrated machine, the positioning strip is in the shape of a long strip plate, the width direction of the positioning strip is arranged vertically, and the outer side wall of the positioning strip can be attached to the groove wall of the positioning groove.

[0012] Set the width direction of the positioning strip vertically to minimize the area of the upper surface of the positioning groove occupying the upper surface of the blanking tray, thereby ensuring that the contact area between the composite film and the blanking tray is less affected, ensuring that the truss manipulator can stably press the composite film on the blanking tray, and ensuring the fast and stable blanking of the microneedle patch.

[0013] In the blanking structure of the above-mentioned microneedle patch punching, rolling, cutting, tearing and pasting integrated machine, a blanking cylinder is connected to the middle of the hinge shaft, the piston rod of the blanking cylinder is fixedly connected to the front end of the blanking tray, and all the positioning strips are located behind the hinge shaft.

[0014] By fixedly connecting the piston rod of the blanking cylinder to the front end of the blanking tray, and the positioning strip is arranged behind the hinge shaft. After the microneedle patch is separated from the composite film, the blanking tray rotates with the rotation of the hinge shaft, and the rear end of the blanking tray swings downward, that is, the blanking tray below the positioning strip swings downward, realizing the blanking of the microneedle patch. Therefore, the position of the positioning strip does not affect the blanking of the microneedle patch on the blanking tray, ensuring the stable blanking of the microneedle patch.

[0015] In the blanking structure of the above-mentioned microneedle patch punching, rolling, cutting, tearing and pasting integrated machine, the positioning strips are arranged in parallel with each other, and a plurality of positioning strips are evenly distributed along the front-rear direction.

[0016] Since the adhesive patches on the cut composite film are arranged in multiple rows and evenly distributed along the front-rear direction, the positioning strips are arranged in parallel and evenly distributed along the front-rear direction. When the adhesive patches are blanked, they are blocked on the positioning strips and are located between two adjacent positioning strips, ensuring the pasting accuracy while improving the stability of blanking.

[0017] In the blanking structure of the above-mentioned microneedle patch punching, rolling, cutting, tearing and pasting integrated machine, the upper end surface of the positioning strip is flush with the upper end surface of the support plate.

[0018] The setting of this structure does not affect the support of the composite film by the support roller, and after installation, the positioning strip can also be stably limited by the support plate. If it protrudes, there will be scraping and other situations during installation. And since the positioning strip is only fixed at both ends on the support plate, when the composite film moves downward, the positioning strip is subjected to the downward pressure of the composite film. Therefore, the two ends of the positioning strip need to be stably set on the support plate to improve the stability of blanking, thereby improving the yield of microneedle patches.

[0019] In the blanking structure of the punching, cutting, tearing and pasting machine for the microneedle patch mentioned above, a punching table is fixed on the frame and located on one side of the soluble microneedle sheet pasting and blanking table. A rotary cylinder is connected to the truss manipulator. A suction cup plate is fixedly connected to the rotating shaft of the rotary cylinder. Multiple pairs of the above-mentioned suction cups are arranged on the suction cup plate. The suction cups are eccentrically arranged relative to the rotation axis. The punching table has a bottom plate on which the cut soluble microneedle original sheets can be placed and can slide out of the punching table in the left and right directions of the frame. Multiple groups of independently arranged ventilation holes are opened on the bottom plate. The truss manipulator can adsorb the soluble microneedle sheets on one group of ventilation holes through the suction cups and transfer them to the composite film tensioned on the soluble microneedle sheet pasting and blanking table, and the other groups of ventilation holes adsorb the cut soluble microneedle original sheets on the bottom plate.

[0020] A cutter that can move in the up and down direction is arranged on this punching table. The cutter is a prior art. The soluble microneedle original sheets are cut by the cutter to form multiple groups of soluble microneedle sheets. One group of soluble microneedle sheets on the bottom plate is sucked by the suction cups through the truss manipulator. At this time, only the ventilation holes corresponding to this group of soluble microneedle sheets on the chassis are ventilated, while the other groups maintain vacuum adsorption. Thus, the suction cups can quickly and stably suck this group of soluble microneedle sheets. After sucking, move the truss manipulator to place this group of soluble microneedle sheets on the composite film of the soluble pasting and blanking table to achieve pasting. When it is necessary to suck other groups of soluble microneedle sheets again, the truss manipulator can be moved in the left and right directions or the rotary cylinder can be driven to drive the suction cup plate to rotate. The suction cup plate can sequentially grab other groups of soluble microneedle sheets on the bottom plate and repeat the above actions. When grabbing, the corresponding ventilation holes on the bottom plate are ventilated, and the soluble microneedle original sheets are adsorbed on the bottom plate through other ventilation holes, facilitating the stable grabbing of the corresponding soluble microneedle sheets and placing them on the cut composite film. During this process, only by moving the truss manipulator a short distance in the left and right directions or driving the rotary cylinder to drive the suction cup plate to rotate 180 degrees, the soluble microneedle sheets at different positions can be sucked. There is no need to repeatedly adjust the relative positions of multiple groups of suction cups on the suction cup plate, reducing error accumulation, thereby ensuring the convenience of sucking and the accuracy of the position, and then improving the yield of the microneedle patch during long-term processing.

[0021] The bottom plate and the frame are connected by slide rails and sliders.

[0022] In the blanking structure of the punching, cutting, tearing and pasting machine for the microneedle patch mentioned above, a rotating disk is connected to the rotating shaft of the rotary cylinder. The suction cup plate is fixed below the rotating disk. The outer shell of the rotary cylinder bulges downward to form a guiding disk corresponding to the rotating disk. The upper end surface of the rotating disk is in contact with the lower end surface of the guiding disk and can rotate relative to each other.

[0023] By the cooperative setting of the rotating disk and the guiding disk, the stability of the rotating shaft driving the suction cup plate to rotate is increased. By increasing the contact area of rotation, the stability of rotation is improved, and further the accuracy of the position after the suction cup rotates is improved.

[0024] In the blanking structure of the punching and cutting waste pasting integrated machine for the microneedle patch described above, the suction cup plate is provided with air suction communication ports corresponding to and communicating with each pair of suction cups one by one.

[0025] The setting of this structure enables individual suction during the suction process of the suction cup, or the entire suction cup to suck the soluble microneedle sheet, facilitating the suction of a pair of soluble microneedle sheets and improving the versatility of the truss manipulator.

[0026] In the blanking structure of the punching and cutting waste pasting integrated machine for the microneedle patch described above, the lower end of the bottom plate is connected with tracheas corresponding to the ventilation ports one by one, and the length direction of the tracheas is arranged along the sliding direction of the bottom plate.

[0027] The setting of the tracheas only requires a plurality of ventilation holes to be opened on the bottom plate, making the processing of the bottom plate convenient, and the setting of the tracheas is also convenient for maintenance and inspection during subsequent long-term production.

[0028] In the blanking structure of the punching and cutting waste pasting integrated machine for the microneedle patch described above, a primary cutting table is arranged on one side of the punching table. On the primary cutting table, a primary cutting knife fixed on the machine frame for initially cutting the soluble microneedle original sheet and a primary cutting plate capable of sliding left and right along the machine frame are provided. The primary cutting plate is located below the primary cutting knife. A material taking manipulator is slidably connected to the machine frame in the transverse direction. A material taking cylinder is installed on the material taking manipulator, and a material taking plate is connected to the material taking shaft of the material taking cylinder. At least two suction cups capable of sucking the cut soluble microneedle original sheet are provided on the material taking plate, and the suction cups are all eccentrically arranged relative to the axis of the material taking shaft. The material taking manipulator can transfer the cut soluble microneedle original sheet on the primary cutting plate to the bottom plate.

[0029] Since the entire soluble microneedle original sheet is relatively large, a primary cutting table can be set. The primary cutting knife can be a cross-shaped blade to cut the soluble microneedle original sheet located on the primary cutting plate. First, the soluble microneedle original sheet is cut into several large pieces, and then the large pieces are sucked and transferred to the punching table by the material taking plate, realizing secondary punching, facilitating the rapid and continuous production and cutting of the microneedle patch. And an eccentric design is also adopted, and by driving the material taking cylinder to rotate, the large pieces at different positions can be grabbed, improving the convenience of grabbing.

[0030] The primary cutting plate and the machine frame are connected by a slide rail and a slider.

[0031] In the punching and blanking structure of the above-mentioned integrated machine for punching, cutting, tearing waste, and pasting of microneedle patches, the material taking plate is strip-shaped, and one end of the material taking plate can be inserted into the punching table.

[0032] With this structure, the base of the punching table does not need to move towards the primary cutting table. Only by rotating can the soluble microneedle original sheet after primary cutting be moved and blanked, which is convenient for control.

[0033] Compared with the prior art, the advantages of the present invention are as follows:

[0034] 1. By setting the positioning strip, when the blanking tray moves downward, the cooperation between the positioning strip and the positioning groove on the blanking tray realizes the guiding of the blanking tray, ensuring that the truss manipulator can stably paste the soluble microneedle sheet on the corresponding pasting sheet. Since it takes time to press it during the pasting process, in order to avoid displacement deviation during the pressing process, the positioning strip ensures the stability of the up and down movement of the blanking tray. During the gradual downward movement, although there is a tensioning roller to tension the composite film, the area of the composite film above the blanking tray is relatively large. Therefore, the positioning strip can also provide a resistance to prevent the composite film from moving downward, helping the microneedle patch to fall off from the composite film, so as to ensure both the stability of pasting and rapid blanking, improving the convenience of blanking and demoulding, and also increasing the product qualification rate.

[0035] 2. When the truss manipulator moves a small distance in the left-right direction or drives the rotating cylinder to drive the suction cup plate to rotate 180 degrees, it can suck the soluble microneedle sheets at different positions. There is no need to repeatedly adjust the relative positions of multiple suction cups on the suction cup plate, reducing the accumulation of errors, thereby ensuring the convenience of suction and the accuracy of position, and then increasing the product qualification rate of the microneedle patch during long-term processing. Description of the Drawings

[0036] Figure 1 is a schematic structural diagram of the existing soluble microneedle original sheet after cutting and the composite film after cutting.

[0037] Figure 2 is a schematic structural diagram of the first embodiment.

[0038] Figure 3 is a side view of the truss manipulator in the present invention.

[0039] Figure 4 is a front view of the first embodiment.

[0040] Figure 5 is Figure 4 a cross-sectional view taken along A-A in

[0041] Figure 6 is Figure 5 a partial enlarged view of A in

[0042] Figure 7 is the side view of the first embodiment.

[0043] Figure 8 is Figure 7 the sectional view taken along B-B in

[0044] Figure 9 is the structural schematic diagram of the installation of the bottom plate and the ventilation pipe part in the first embodiment.

[0045] Figure 10 is the structural schematic diagram of the paste feeding table for soluble microneedle patches in the present invention.

[0046] Figure 11 is the structural schematic diagram of the paste feeding table for soluble microneedle patches in another direction in the present invention.

[0047] Figure 12 is the partial structural schematic diagram of the existing cut soluble microneedle original sheet and the truss manipulator suction cup.

[0048] In the figure, 1, soluble microneedle patch; 2, composite film; 3, paste sheet; 31, inner bonding surface; 4, soluble microneedle original sheet; 5, frame; 51, material taking manipulator; 51a, material taking cylinder; 52, material taking plate; 53, suction cup; 6, cutting roller knife seat; 7, paste feeding table for soluble microneedle patches; 71, support plate; 72, feeding tray; 72a, positioning groove; 72b, adsorption hole; 73, positioning strip; 74, hinge shaft; 75, tensioning roller; 76, feeding cylinder; 76a, piston rod; 8, truss manipulator; 81, rotating cylinder; 81a, rotating disk; 81b, guiding disk; 82, suction cup plate; 83, suction cup; 83a, air intake communication port; 9, punching table; 91, bottom plate; 92, ventilation hole; 93, ventilation pipe; 10, primary cutting table; 101, primary cutting plate; 102, primary cutting knife.

[0049] Figure 12 Among them, a, b, c, and d are multiple groups of soluble microneedle patches at different positions; e and f are two groups of suction cups at different positions on the truss manipulator. Detailed implementation manners

[0050] The following are specific embodiments of the present invention and in combination with the accompanying drawings, the technical solutions of the present invention are further described, but the present invention is not limited to these embodiments.

[0051] Embodiment 1

[0052] As Figure 2 and Figure 5As shown, the punching and blanking structure of the micro needle patch punching, rolling cutting, waste tearing and pasting integrated machine. The micro needle patch punching, rolling cutting, waste tearing and pasting integrated machine includes a frame 5, a cutting roller knife seat 6 arranged on the frame 5 and capable of rolling cutting the composite film 2, and a soluble micro needle patch pasting and blanking table 7 arranged on the frame 5 and located behind the cutting roller knife seat 6. This punching and blanking structure includes a truss manipulator 8 slidably connected to the frame 5 in the left-right direction and capable of moving the soluble micro needle patch 1 to the composite film 2 and pressing the composite film 2 onto the blanking plate 72. The truss manipulator 8 is located on one side of the soluble micro needle patch pasting and blanking table 7. The soluble micro needle patch pasting and blanking table 7 includes two support plates 71 arranged opposite to each other in the left-right direction. A plurality of tension rollers 75 capable of tensioning the cut composite film 2 are connected to the support plates 71. A hinge shaft 74 is rotatably connected between the two support plates 71. A blanking plate 72 capable of moving up and down relative to the hinge shaft 74 is connected to the hinge shaft 74.

[0053] Specifically, as Figure 2 , Figure 3 , Figure 5 , Figure 6 , Figure 9 and Figure 12 shown, a plurality of positioning strips 73 are fixedly connected to the upper ends of the support plates 71. Positioning grooves 72a corresponding to the positioning strips 73 one by one are formed on the blanking plate 72. The positioning strips 73 are inserted into the corresponding positioning grooves 72a and can slide relative to the groove walls of the positioning grooves 72a. The top surface of the positioning strip 73 is lower than the highest point of the tension roller 75 and can be higher than the upper end surface of the blanking plate 72. The positioning strips 73 are arranged at intervals in the front-rear direction. The truss manipulator 8 has a downwardly protruding suction cup 83. When the truss manipulator 8 presses down, the suction cup 83 can be inserted between two adjacent positioning strips 73.

[0054] During production, first, the composite film 2 is roll-cut by the cutting roller tool holder 6. The cutting roller tool holder 6, like the cutting roller tool holder 6 in the aforementioned comparative document, realizes the cutting of the composite film 2 through the cooperation of the bottom roller and the cutting roller. After cutting, the composite film 2 is tensioned by the tensioning roller 75 of the soluble microneedle sheet pasting blanking table 7. Then, the truss manipulator 8 transfers the cut soluble microneedle sheet 1 onto the cut composite film 2 and presses the composite film 2 against the blanking plate 72. After pressing, the truss manipulator 8 and the blanking plate 72 move downward synchronously until the positioning strip 73 disengages from the positioning groove 72a. At this time, the soluble microneedle sheet 1 adheres to the paste sheet 3 on the composite film 2 and then separates from the composite film 2, realizing the rapid blanking of the microneedle patch. By setting the top surface of the positioning strip 73 below the highest point of the tensioning roller 75, and when the blanking plate 72 gradually moves downward, the top surface of the positioning strip 73 is higher than the upper end surface of the blanking plate 72, and the positioning strips 73 are distributed at intervals in the front-rear direction. The truss manipulator 8 has a downwardly protruding suction cup 83 that can adsorb the soluble microneedle sheet 1. When the truss manipulator 8 presses down, the suction cup 83 can be embedded between two adjacent positioning strips 73. Therefore, the positioning strip 73 has a resistance to push the composite film 2 upward, while the truss manipulator 8 and the blanking plate 72 have a downward thrust on the composite film 2. Under the combined action of the two, the microneedle patch adhered to the composite film 2 can quickly detach from the composite film 2, facilitating the blanking of the microneedle patch. After the microneedle patch detaches from the composite film 2 and is placed on the blanking plate 72, the truss manipulator 8 is moved upward, and the blanking plate 72 rotates around the hinge shaft 74, enabling the microneedle patch to quickly slide out of the blanking plate 72, realizing blanking.

[0055] In this application, by setting the positioning strip 73, when the blanking plate 72 moves downward, the cooperation between the positioning strip 73 and the positioning groove 72a on the blanking plate 72 realizes the guiding of the blanking plate 72, ensuring that the truss manipulator 8 can stably paste the soluble microneedle sheet 1 on the corresponding paste sheet 3. Since it takes time to press it during the pasting process, in order to avoid displacement deviation during the pressing process, the stability of the up and down movement of the blanking plate 72 is ensured by the positioning strip 73. During the gradual downward movement, although the tensioning roller 75 tensions the composite film 2, the area of the composite film 2 above the blanking plate 72 is relatively large. Therefore, the positioning strip 73 can also provide a resistance to prevent the composite film 2 from moving downward, helping the microneedle patch to fall off from the composite film 2, thus ensuring both the stability of pasting and realizing rapid blanking, improving the convenience of blanking and demoulding, and also increasing the product yield.

[0056] During the specific material taking process, when the suction cup 83 of the truss manipulator 8 is at the position of e in Figure 12 it can successively grasp two groups of soluble microneedle sheets 1, namely a and b, of the cut soluble microneedle original sheet 4 in Figure 12 ​

[0057] When the suction cup 83 of the truss manipulator 8 rotates 180° and is located at the position of f in Figure 12 , it can grasp the soluble microneedle sheets 1 of group c of the cut soluble microneedle master sheets 4 in Figure 12 . After grasping, the suction cup 83 rotates 180° again and is located at the position of e in Figure 12 . The soluble microneedle sheets 1 on the suction cup 83 are placed on the composite film 2. Repeating the above steps can achieve the grasping of the soluble microneedle sheets 1 of group d, making the grasping of the truss manipulator 8 more convenient and concise with fewer parameters to be adjusted, improving its grasping accuracy. Moreover, no matter which of the c or d groups is grasped, the suction cup 83 can be rotated so that it can be pasted on the cut and pasted sheets 3 in the same row of the composite film.

[0058] As Figure 4 , Figure 5 , Figure 6 , Figure 10 and Figure 11 shown, the positioning strip 73 is in the shape of a long strip plate, the width direction of the positioning strip 73 is arranged vertically, the outer side wall of the positioning strip 73 can be attached to the groove wall of the positioning groove 72a, the middle part of the hinge shaft 74 is connected with the blanking cylinder 76, the piston rod 76a of the blanking cylinder 76 is fixedly connected to the front end of the blanking plate 72, all the positioning strips 73 are located behind the hinge shaft 74, the positioning strips 73 are arranged parallel to each other, a plurality of positioning strips 73 are evenly distributed along the front-rear direction, the upper end surface of the positioning strip 73 is flush with the upper end surface of the support plate 71, and a plurality of suction holes 72b are arranged in front of the blanking plate 72, and all the suction holes 72b are located in front of the positioning strip 73.

[0059] As Figure 3 , Figure 4 , Figure 8 and Figure 9As shown in the figure, a punching table 9 is fixed on the frame 5 on one side of the soluble micro-needle sheet pasting and blanking table 7. A rotary cylinder 81 is connected to the truss manipulator 8. A suction cup plate 82 is fixedly connected to the rotating shaft of the rotary cylinder 81. A plurality of pairs of the above-mentioned suction cups 83 are provided on the suction cup plate 82. The suction cups 83 are eccentrically arranged relative to the axis of the rotating shaft. The punching table 9 has a bottom plate 91 on which the cut soluble micro-needle original sheet 4 can be placed and can slide out of the punching table 9 in the left and right directions of the frame 5. A plurality of groups of independently arranged ventilation holes 92 are formed on the bottom plate 91. The truss manipulator 8 can adsorb the soluble micro-needle sheet 1 on one group of ventilation holes 92 through the suction cups 83 and transfer it to the composite film 2 tensioned on the soluble micro-needle sheet pasting and blanking table 7, and the other groups of ventilation holes 92 adsorb the cut soluble micro-needle original sheet 4 on the bottom plate 91. A rotating disc 81a is connected to the rotating shaft of the rotary cylinder 81. The outer shell of the rotary cylinder 81 protrudes downward to form a guiding disc 81b corresponding to the rotating disc 81a. The upper end surface of the rotating disc 81a is in contact with the lower end surface of the guiding disc 81b and can rotate relatively. The suction cup plate 82 is provided with air suction communication ports 83a corresponding to and communicating with each pair of suction cups 83 one by one.

[0060] As Figure 4 and Figure 9 shown, a trachea 93 corresponding to the ventilation holes 92 one by one is connected to the lower end of the bottom plate 91. The length direction of the trachea 93 is arranged along the sliding direction of the bottom plate 91.

[0061] As Figure 4 , Figure 7 and Figure 8 shown, a primary cutting table 10 is arranged on one side of the punching table 9. A primary cutting knife 102 fixed on the frame 5 for initially cutting the soluble micro-needle original sheet 4 and a primary cutting plate 101 capable of sliding in the left and right directions of the frame 5 are arranged on the primary cutting table 10. The primary cutting plate 101 is located below the primary cutting knife 102. A material taking manipulator 51 is slidably connected to the frame 5 in the transverse direction. A material taking cylinder 51a is installed on the material taking manipulator 51. A material taking plate 52 is connected to the material taking shaft of the material taking cylinder 51a. At least two material suction discs 53 capable of sucking the cut soluble micro-needle original sheet 4 are provided on the material taking plate 52. The material suction discs 53 are all eccentrically arranged relative to the axis of the material taking shaft. The material taking manipulator 51 can transfer the cut soluble micro-needle original sheet 4 on the primary cutting plate 101 to the bottom plate 91. The material taking plate 52 is strip-shaped, and one end of the material taking plate 52 can be inserted into the punching table 9.

[0062] Embodiment 2

[0063] The content of this embodiment is basically the same as that of Embodiment 1, and the difference lies in that: a ventilation channel corresponding to each group of ventilation holes 92 one by one is opened vertically from top to bottom in the bottom plate 91, and the outlet end of the ventilation channel is connected to an external trachea.

[0064] With the above structure setting, although it involves a major modification to the bottom plate 91, it can save the installation holes required for external air pipes, facilitating control and installation.

[0065] The specific embodiments described herein are merely illustrative of the spirit of the present invention. Those skilled in the art to which the present invention pertains can make various modifications or supplements to the described specific embodiments or use similar methods for substitution, without departing from the spirit of the present invention or exceeding the scope defined by the appended claims.

Claims

1. A punching and blanking structure of a micro-needle patch punching, rolling cutting, waste tearing and pasting integrated machine. The micro-needle patch punching, rolling cutting, waste tearing and pasting integrated machine includes a frame (5), a cutting roller knife seat (6) arranged on the frame (5) and capable of rolling cutting a composite film (2), and a soluble micro-needle sheet pasting and blanking table (7) arranged on the frame (5) and located behind the cutting roller knife seat (6). This punching and blanking structure includes a truss manipulator (8) slidably connected to the frame (5) in the left-right direction and capable of moving a soluble micro-needle sheet (1) to the composite film (2) and pressing the composite film (2) onto the blanking plate (72). The truss manipulator (8) is located on one side of the soluble micro-needle sheet pasting and blanking table (7). The soluble micro-needle sheet pasting and blanking table (7) includes two support plates (71) arranged opposite to each other in the left-right direction. A plurality of tension rollers (75) capable of tensioning the cut composite film (2) are connected to the support plates (71). A hinge shaft (74) is rotatably connected between the two support plates (71). A blanking plate (72) capable of moving up and down relative to the hinge shaft (74) is connected to the hinge shaft (74). It is characterized in that, A plurality of positioning bars (73) are fixedly connected to the upper end of the support plate (71). Positioning grooves (72a) corresponding to the positioning bars (73) one by one are formed in the blanking tray (72). The positioning bars (73) are embedded in the corresponding positioning grooves (72a) and can slide relative to the groove walls of the positioning grooves (72a). The top surface of the positioning bar (73) is lower than the highest point of the tension roller (75) and can be higher than the upper end surface of the blanking tray (72). The positioning bars (73) are arranged at intervals in the front-rear direction. The truss manipulator (8) has a downwardly protruding suction cup (83). When the truss manipulator (8) presses down, the suction cup (83) can be embedded between two adjacent positioning bars (73).

2. The blanking structure of the micro-needle patch punching, roll-cutting, waste tearing and pasting integrated machine according to claim 1, characterized in that, The positioning bar (73) is in the shape of a long strip plate. The width direction of the positioning bar (73) is arranged vertically. The outer side wall of the positioning bar (73) can be attached to the groove wall of the positioning groove (72a).

3. The blanking structure of the micro-needle patch punching, rolling cutting, waste tearing and pasting integrated machine according to claim 1 or 2, characterized in that, A blanking cylinder (76) is connected to the middle of the hinge shaft (74). The piston rod (76a) of the blanking cylinder (76) is fixedly connected to the front end of the blanking tray (72). All the positioning bars (73) are located behind the hinge shaft (74).

4. The blanking structure of the punching, cutting, tearing and waste pasting integrated machine for the microneedle patch according to claim 1 or 2, characterized in that, The positioning bars (73) are arranged parallel to each other. A plurality of positioning bars (73) are evenly distributed along the front-rear direction.

5. The blanking structure of the punching, cutting, tearing and waste pasting integrated machine for the microneedle patch according to claim 1 or 2, characterized in that, The upper end surface of the positioning bar (73) is flush with the upper end surface of the support plate (71).

6. The blanking structure of the punching, cutting, tearing and pasting integrated machine for the microneedle patch according to claim 1 or 2, characterized in that, A plurality of adsorption holes (72b) are arranged in front of the blanking tray (72). All the adsorption holes (72b) are located in front of the positioning bars (73).

7. The blanking structure of the punching, cutting, tearing and waste pasting integrated machine for the microneedle patch according to claim 1 or 2, characterized in that, A punching table (9) is fixed on the frame (5) on one side of the soluble microneedle sheet pasting and blanking table (7). A rotary cylinder (81) is connected to the truss manipulator (8). A suction cup plate (82) is fixedly connected to the rotating shaft of the rotary cylinder (81). A plurality of pairs of the above suction cups (83) are arranged on the suction cup plate (82). The suction cup (83) is eccentrically arranged relative to the axis of the motor shaft. The punching table (9) has a bottom plate (91) on which the cut soluble microneedle original sheet (4) can be placed and can slide out of the punching table (9) in the left-right direction of the frame (5). A plurality of groups of independently arranged ventilation holes (92) are formed in the bottom plate (91). The truss manipulator (8) can adsorb the soluble microneedle sheet (1) on one group of ventilation holes (92) through the suction cup (83) and transfer it to the composite film (2) tensioned on the soluble microneedle sheet pasting and blanking table (7), and the other groups of ventilation holes (92) adsorb the cut soluble microneedle original sheet (4) on the bottom plate (91).

8. The blanking structure of the punching, cutting, tearing and waste pasting integrated machine for the microneedle patch according to claim 7, wherein, A rotating disk (81a) is connected to the rotating shaft of the rotary cylinder (81). The outer shell of the rotary cylinder (81) protrudes downward to form a guide disk (81b) corresponding to the rotating disk (81a). The upper end surface of the rotating disk (81a) is attached to the lower end surface of the guide disk (81b) and can rotate relative to it.

9. The punching and blanking structure of the micro-needle patch punching, roll-cutting, waste-pasting integrated machine according to claim 7, characterized in that, Suction connection ports (83a) corresponding to each pair of suction cups (83) one by one are formed in the suction cup plate (82).

10. The blanking structure of the micro-needle patch punching, roll-cutting, waste tearing and pasting integrated machine according to claim 7, characterized in that, A ventilation pipe (93) corresponding to each ventilation hole (92) is connected to the lower end of the bottom plate (91), and the length direction of the ventilation pipe (93) is arranged along the sliding direction of the bottom plate (91).

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