Cervical and vaginal cast-off cell sampling device for self-sampling HPV (human papillomavirus) detection

Abstract

The invention discloses a cervix uteri and vagina exfoliated cell sampling device for self-sampling HPV (human papillomavirus) detection, which comprises a handle, one end of the handle is fixedly connected with a spherical head body, a sampling brush head is fixedly arranged on the outer side of one end of the spherical head body of the handle, and sampling brushes are uniformly arranged on the surface of the spherical head body. The outer side of the handle is sleeved with a slidable telescopic sleeve shell, and when sampling operation needs to be carried out, the telescopic sleeve shell can slide away from one side of the sampling brush head and one side of the sampling brush brush by sliding the telescopic sleeve shell, so that the sampling brush head and the sampling brush brush are exposed to be used for collecting cervical and vagina exfoliated cells; in a non-sampling state, the sampling brush head and the sampling brush can be sleeved with the telescopic sleeve shell, so that a protection effect is achieved; compared with a traditional sampling brush or cotton swab, the contact area between the sampling brush or cotton swab and the cervix uteri and the vagina wall is greatly increased, the area where pathological cells possibly exist can be covered more comprehensively, the risk of missing sampling is reduced, and the accuracy of a detection result is improved.

Description

Technical Field

[0001] The present invention relates to the field of gynecological medical devices, and particularly to a cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection. Background Art

[0002] With the wide promotion of HR-HPV testing as a primary screening strategy for cervical cancer, self-sampling high-risk human papillomavirus testing in the vagina has gradually gained attention and been standardized in cervical cancer screening; relevant research reports show that the accuracy of self-sampling and doctor-sampling HPV testing is similar; however, in the process of self-sampling, how to accurately collect cervical and vaginal exfoliated cells, especially cervical exfoliated cells, has become a key issue.

[0003] Currently, the commonly used sampling tools for self-sampling HR-HPV are sampling brushes or cotton swabs; these traditional tools have obvious defects: firstly, their contact surfaces with the cervix and vaginal wall are relatively small, making it difficult to fully cover the areas where diseased cells may exist; secondly, during sampling, the subject needs to move the sampling tool in multiple directions by themselves. Due to the lack of professional knowledge and experience, the subject often cannot ensure the standardization and comprehensiveness of sampling, thereby affecting the comprehensive collection of cells, reducing the accuracy of the test results, and possibly leading to missed diagnosis or misdiagnosis. Summary of the Invention

[0004] In view of the problems existing in the commonly used sampling tools for HR-HPV during use, the present invention is proposed.

[0005] Therefore, the purpose of the present invention is to provide a cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection, which solves the above technical problems.

[0006] To achieve the above purpose, the present invention provides the following technical solutions:

[0007] A cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection includes a handle. One end of the handle is fixedly connected to a spherical head body. A sampling brush head is fixedly provided on the outer side of one end of the handle where the spherical head body is located. Sampling brushes are evenly arranged on the surface of the spherical head body. A slidable telescopic sleeve is sleeved on the outer side of the handle. When sampling operation needs to be performed, the telescopic sleeve can be slid to slide away from one side of the sampling brush head and the sampling brushes, so as to expose the sampling brush head and the sampling brushes for collecting cervical and vaginal exfoliated cells; in the non-sampling state, the telescopic sleeve can be sleeved on the outer sides of the sampling brush head and the sampling brushes to play a protective role.

[0008] Preferably, the sampling brushes are of an arc structure.

[0009] Preferably, the sampling brush head has a multi-layer petal-shaped structure and is in a contracted state under the action of the telescopic sleeve when not in use, facilitating insertion into the vagina; during sampling, by sliding away from the telescopic sleeve, the contact area with the cervix and vaginal wall is increased. The petal surface of the sampling brush head is made of a soft and adsorbent material, which is medical-grade silicone.

[0010] Preferably, the multi-layer petal-shaped structure of the sampling brush head is composed of multiple groups of components. Each group of components includes two parts. The top of one part is arc-shaped, and the arc-shaped top can block the end of the other part; this design enables the arc-shaped top to play a buffering role when contacting the cervix and vaginal wall during sampling, reducing irritation to sensitive tissues, while avoiding direct scraping of tissues by the end of the other part and causing damage. Additionally, the arc-shaped top can also guide cell attachment, assisting the end of the other part to collect cells more efficiently while blocking, improving the comprehensiveness and safety of cell collection.

[0011] Preferably, the handle includes a handle arm thread, and the handle is slidably connected to the telescopic sleeve through the handle arm thread. A scale is provided on the surface of the handle arm thread.

[0012] Preferably, an adjustment groove is provided on the inner wall of the telescopic sleeve. An adjustment rod is movably arranged in the adjustment groove. One end of the adjustment rod movably penetrates through the telescopic sleeve and is fixedly connected to a pulling ring, and the other end movably penetrates through a mounting block and is fixedly connected to a sealing arc plate. The sealing arc plate is made of elastic silicone. A spring frame is sleeved outside the adjustment rod. One end of the spring frame is fixedly connected to the sealing arc plate, and the other end is fixedly connected to the mounting block. The sealing arc plate slides in the adjustment groove.

[0013] Preferably, a guiding bending section is provided at one end of the handle where the sampling brush head is located.

[0014] Preferably, the guiding bending section includes multiple groups of guiding bending blocks, and the multiple groups of guiding bending blocks are rotatably connected through guiding bending joints.

[0015] Preferably, one end of the sleeve plate is provided with an opening, and the opening size is larger than the spherical head body. The other end of the sleeve plate is fixedly provided with a sleeve plate. The sleeve plate is slidably sleeved outside the handle. Finger sleeves are fixedly provided at both ends of the surface of the sleeve plate.

[0016] In the above technical solution, the technical effects and advantages provided by the present invention:

[0017] In the present invention, by setting the sampling brush head to a multi-layer petal-like structure, and the sampling brushes are evenly distributed on the surface of the spherical head body. Compared with traditional sampling brushes or cotton swabs, the contact surface with the cervix and vaginal wall is greatly increased, which can more comprehensively cover the areas where diseased cells may exist, reduce the risk of missed sampling, and improve the accuracy of test results. Moreover, the multi-layer petal-like structure of the sampling brush head is composed of multiple groups of components, and two parts of each group of components cooperate with each other. The arc-shaped top can both buffer and guide cell attachment, assisting the other end to efficiently collect cells, further ensuring the comprehensiveness of cell collection.

[0018] In the present invention, by setting a guiding bending section on the handle, and the guiding bending section is formed by rotatably connecting multiple groups of guiding bending blocks through guiding bending joints, users can flexibly adjust the bending degree of the guiding bending section according to their own body structure and sampling needs, facilitating the accurate delivery of the sampling device to the sampling site. Especially for some examinees with unskilled operations, the sampling difficulty is reduced.

[0019] In the present invention, by setting a slidable telescopic sleeve on the outside of the handle, in the non-sampling state, the telescopic sleeve covers the outside of the sampling brush head and sampling brushes, playing a protective role, preventing the sampling components from being contaminated or damaged, and extending the service life. Moreover, it can also facilitate the protection of sample storage, and finger sleeves are fixedly provided at both ends of the surface of the sleeve plate. When operating, users insert their fingers into the finger sleeves, which can increase the stability of pulling and shrinking the telescopic sleeve by hand. Brief Description of the Drawings

[0020] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required to be used in the embodiments. Obviously, the drawings described below are only some embodiments recorded in the present invention. For those of ordinary skill in the art, other drawings can also be obtained based on these drawings.

[0021] Figure 1 It is a schematic structural diagram of a cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection proposed by the present invention;

[0022] Figure 2 It is Figure 1 a schematic structural diagram during sampling;

[0023] Figure 3 It is Figure 1 another schematic structural diagram of the handle part;

[0024] Figure 4 It is Figure 1 a schematic structural diagram of the handle part provided with a guiding bending section;

[0025] Figure 5 It is Figure 4 a schematic structural diagram of the guiding bending section.

[0026] Description of the reference numerals:

[0027] 1. Handle; 2. Telescopic housing; 3. Housing plate; 4. Finger cot; 5. Sampling brush head; 6. Spherical head body; 7. Sampling brush; 1-1 Thread of the handle arm; 101. Guiding bending section; 102. Guiding bending section block; 103. Guiding bending joint; 201. Adjusting groove; 202. Mounting block; 203. Adjusting rod; 204. Pulling ring; 205. Spring frame; 206. Sealing arc plate. Detailed implementation manners

[0028] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0029] An embodiment of the present invention discloses a cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection.

[0030] Referring to Figures 1-5 , a cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection includes a handle 1. One end of the handle 1 is fixedly connected to a spherical head body 6. A sampling brush head 5 is fixedly provided on the outer side of one end of the handle 1 located at the spherical head body 6. Sampling brushes 7 are evenly arranged on the surface of the spherical head body 6. A slidable telescopic housing 2 is sleeved on the outer side of the handle 1. When a sampling operation needs to be performed, the telescopic housing 2 can be slid to slide away from one side of the sampling brush head 5 and the sampling brushes 7, so as to expose the sampling brush head 5 and the sampling brushes 7 for collecting cervical and vaginal exfoliated cells; in a non-sampling state, the telescopic housing 2 can be sleeved on the outer sides of the sampling brush head 5 and the sampling brushes 7 to play a protective role.

[0031] Referring to Figures 1-3 , the sampling brush 7 is of an arc structure.

[0032] Referring to Figures 1-3 , the sampling brush head 5 is of a multi-layer petal-shaped structure and is in a contracted state under the action of the telescopic housing 2 when not in use, which is convenient for insertion into the vagina; during sampling, by sliding away from the telescopic housing 2, the contact area with the cervix and the vaginal wall is increased. The petal surface of the sampling brush head 5 is made of a soft and adsorbent material, and the material is medical-grade silica gel;

[0033] It is worth noting that the multi-layer petal-shaped structure of the sampling brush head 5 is ingeniously installed on the handle 1 at an oblique angle of 45°-60°; this design enables the multi-layer petal-shaped structure to fit the sampling part in all directions and at multiple angles when unfolded, maximizing the adsorption efficiency of the sample;

[0034] The surfaces of the 5-petal sampling brush head and the sampling brush 7 are made of soft and adsorbent medical-grade silicone. When contacting the cervix and vaginal wall, it can gently collect cells, reduce the irritation and damage to sensitive tissues, and reduce the discomfort of the examinee. At the same time, the adsorbability of silicone helps the cells to adhere, improving the sampling effect.

[0035] Refer to Figures 1-3 , the multi-layer petal-shaped structure of the sampling brush head 5 is composed of multiple groups of components. Each group of components contains two parts. The top of one part is arc-shaped, and the arc-shaped top can block the end of the other part. This design enables the arc-shaped top to play a buffering role when contacting the cervix and vaginal wall during sampling, reducing the irritation to sensitive tissues. At the same time, it avoids the direct scratching of the tissue by the end of the other part, causing damage. Moreover, the arc-shaped top can also guide the cell adhesion, assisting the end of the other part to collect cells more efficiently while blocking, improving the comprehensiveness and safety of cell collection.

[0036] Refer to Figure 3 , the handle includes a handle arm thread. The handle is slidably connected to the telescopic sleeve through the handle arm thread. A scale is provided on the surface of the handle arm thread.

[0037] The handle 1 is slidably connected to the telescopic sleeve 2 through the handle arm thread 1-1. Compared with ordinary socket connections, this connection method allows the user to more precisely control the sliding of the telescopic sleeve 2. During the sampling process, the user can slowly and steadily slide the telescopic sleeve 2 according to actual needs, thereby better controlling the exposure degree of the sampling brush head and the sampling brush. For example, when the user feels that the sampling position is not accurate enough, the position of the telescopic sleeve can be finely adjusted to ensure that the sampling part can better contact the target area. Among them, the scale provided on the surface of the handle arm thread 1-1 provides a quantitative operation reference for the user.

[0038] It should be noted that it can also be set to use the way of slot and buckle cooperation here. For example, elastic telescopic protrusions are evenly arranged on the surface of the handle 1, and corresponding card slots for the protrusions are opened in the telescopic sleeve 2. The surface of the protrusion is arc-shaped. After sliding the telescopic sleeve 2, the protrusion can be squeezed, and the protrusion enters the card slot for positioning, so as to achieve the function of adjusting the position of the telescopic sleeve. And applying an external force again to the telescopic sleeve can drive the protrusion out of the card slot of the telescopic sleeve frame 2. The design of this structure is more convenient for medical staff to move the telescopic sleeve 2.

[0039] Refer to Figure 3, an adjustment groove 201 is provided on the inner wall of the telescopic sleeve. An adjustment rod 203 is movably arranged in the adjustment groove 201. One end of the adjustment rod 203 movably penetrates through the telescopic sleeve and is fixedly connected to the pulling ring 204, and the other end movably penetrates through the mounting block 202 and is fixedly connected to the sealing arc plate 206. The sealing arc plate 206 is made of elastic silica gel. A spring frame 205 is sleeved on the outer side of the adjustment rod 203. One end of the spring frame 205 is fixedly connected to the sealing arc plate 206, and the other end is fixedly connected to the mounting block 202. The sealing arc plate 206 slides in the adjustment groove 201. After the operator moves this device to a suitable position at the sampling point, by pulling the pulling ring 204, the adjustment rod 203 is driven to move, and then the sealing arc plate 206 slides into the adjustment groove 201. This design enables the user to operate the opening and closing of the telescopic sleeve more conveniently, thus facilitating the removal of the sampling brush. After sampling is completed, release the pulling ring 204. Under the elastic force of the spring frame 205, the sealing arc plate 206 seals the opening of the telescopic sleeve, thereby enhancing protection and sealing performance. The sealing arc plate 206 is made of elastic silica gel and is easy to deform and recover. When the telescopic sleeve is sleeved outside the sampling head and the sampling brush, it can better play a sealing role. It can prevent external pollutants such as dust and bacteria from entering the sampling components, effectively protecting the sampling head and the sampling brush. At the same time, during the sampling process, this sealing structure can also prevent the cell sample from being interfered by the outside world during sampling.

[0040] Refer to Figure 4 , a guiding bending section 101 is provided at one end of the handle 1 where the sampling head 5 is located.

[0041] It should be noted that considering the certain physiological curvatures of the human vagina and cervix, the invention provides the guiding bending section 101, which can enable the sampling device to better fit these curvatures, reach the sampling site more smoothly, and reduce discomfort or injury caused by the mismatch between the instrument and the body structure. Through the flexible adjustment of the guiding bending section 101, the sampling head 5 and the sampling brush 7 can better contact the cervix and the vaginal wall, increasing the contact area, improving the accuracy and reliability of sampling, and helping to obtain a more comprehensive and representative cell sample.

[0042] Refer to Figures 4-5 , the guiding bending section 101 includes multiple groups of guiding bending blocks 102, and the multiple groups of guiding bending blocks 102 are rotationally connected by guiding bending joints 103.

[0043] It should be noted that by Figure 4It can be seen that the multi-layer petal-shaped structure is composed of multiple groups of components, and each group of components is installed on the handle 1 at an oblique angle of 45°-60°. This can ensure that the multiple groups of components of the multi-layer petal-shaped structure can better adsorb samples after being unfolded. Moreover, each component part is evenly and reasonably distributed on the surface of the guiding bending section block 102. This layout enables the guiding bending section blocks 102 to produce a certain degree of bending deformation according to the sampling requirements, without disturbing the excellent adsorption effect of the multiple groups of components at all, ensuring that exfoliated cell samples of the cervix and vagina can be stably and efficiently collected in various operating postures.

[0044] Referring to Figures 1-2 , one end of the sleeve plate 3 is provided with an opening, and the opening size is larger than the spherical head body 6. The other end of the sleeve plate 3 is fixedly provided with a sleeve plate 3. The sleeve plate 3 is slidably sleeved on the outside of the handle 1, and finger sleeves 4 are respectively fixedly provided at both ends of the surface of the sleeve plate 3; when the user operates, the fingers are inserted into the finger sleeves 4, which can increase the stability of the user's hand to pull and retract the telescopic sleeve 2.

[0045] In the present invention, when in use, the user washes both hands, inserts the fingers into the finger sleeves 4 on the sleeve plate 3, and holds the handle 1; check whether the telescopic sleeve 2 is in the position of completely covering the sampling brush head 5 and the sampling brush 7 to ensure the protection of the sampling components and avoid contamination;

[0046] Sampling operation: Slowly insert the device into the vagina. During the insertion process, since the sampling brush head 5 is in a contracted state under the action of the telescopic sleeve 2, it is convenient to insert smoothly and reduce the discomfort of the subject;

[0047] When the device reaches a suitable position near the cervix, the user slides the telescopic sleeve 2 forcefully with the fingers, so that the telescopic sleeve 2 slowly slides away from one side of the sampling brush head 5 and the sampling brush 7, exposing the sampling brush head 5 and the sampling brush 7; at this time, the multi-layer petal-shaped sampling brush head 5 automatically unfolds after losing the restraint of the telescopic sleeve 2, increasing the contact area with the cervix and the vaginal wall. At the same time, the arc-shaped sampling brush 7 on the surface of the spherical head body 6 can also contact the corresponding parts;

[0048] The user can gently rotate the handle 1 according to the actual situation and use the sampling brush head 5 and the sampling brush 7 to collect exfoliated cells of the cervix and vagina. Since the multiple guiding bending section blocks 102 of the guiding bending section 101 of the handle 1 can rotate, the user can flexibly adjust the sampling angle to ensure comprehensive collection of cells; the arc-shaped top in the components of the sampling brush head 5 buffers and guides the attachment of cells, and the other end efficiently collects. The whole process is efficient and safe;

[0049] Post-sampling treatment: After sampling, slide the telescopic sleeve 2 back over the sampling brush head 5 and the sampling brush 7 to protect the sampling components; then, take out this device to complete the sampling.

[0050] It should be understood that the embodiments of the present application are not limited to the exact structures described above and shown in the drawings, and various modifications and changes can be made without departing from its scope. The scope of the embodiments of the present application is only limited by the appended claims.

[0051] The above-described embodiments merely represent several implementation manners of the embodiments of the present application. The description thereof is relatively specific and detailed, but it should not be construed as a limitation on the scope of the invention patent. It should be noted that for those of ordinary skill in the art, without departing from the concept of the embodiments of the present application, several variations and improvements can still be made, and these all belong to the protection scope of the embodiments of the present application.

Claims

1. A cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection, comprising a handle (1), characterized in that, One end of the handle (1) is fixedly connected to the spherical head body (6). A sampling brush head (5) is fixedly provided on the outer side of one end of the handle (1) located at the spherical head body (6). Sampling brushes (7) are evenly arranged on the surface of the spherical head body (6). A slidable telescopic sleeve (2) is sleeved on the outer side of the handle (1). When a sampling operation needs to be performed, the telescopic sleeve (2) can be slid so that it slides away from one side of the sampling brush head (5) and the sampling brushes (7), thereby exposing the sampling brush head (5) and the sampling brushes (7) for collecting exfoliated cells from the cervix and vagina; in the non-sampling state, the telescopic sleeve (2) can be sleeved on the outer side of the sampling brush head (5) and the sampling brushes (7) to play a protective role.

2. The cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection according to claim 1, characterized in that, The sampling brush (7) is of an arc-shaped structure.

3. The cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection according to claim 1, wherein The sampling brush head (5) is of a multi-layer petal-shaped structure and is in a contracted state under the action of the telescopic sleeve (2) when not in use, which is convenient for insertion into the vagina; during sampling, by sliding away from the telescopic sleeve (2), the contact area with the cervix and the vaginal wall is increased. The petal surface of the sampling brush head (5) is made of a soft and adsorbent material, and the material is medical-grade silicone.

4. A cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection according to claim 3, characterized in that, The multi-layer petal-shaped structure of the sampling brush head (5) is composed of multiple groups of components. Each group of components contains two parts, one of which has an arc-shaped top, and the arc-shaped top can block the end of the other.

5. A cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection according to claim 1, characterized in that, The handle (1) includes a handle arm thread (1-1). The handle (1) is slidably connected to the telescopic sleeve (2) through the handle arm thread (1-1). A scale is provided on the surface of the handle arm thread (1-1).

6. The cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection according to claim 1, wherein, An adjustment groove (201) is opened on the inner wall of the telescopic sleeve (2). An adjustment rod (203) is movably arranged in the adjustment groove (201). One end of the adjustment rod (203) movably passes through the telescopic sleeve (2) and is fixedly connected to a pulling ring (204), and the other end movably passes through a mounting block (202) and is fixedly connected to a sealing arc plate (206). The sealing arc plate (206) is made of elastic silicone. A spring frame (205) is sleeved on the outer side of the adjustment rod (203). One end of the spring frame (205) is fixedly connected to the sealing arc plate (206), and the other end is fixedly connected to the mounting block (202). The sealing arc plate (206) slides in the adjustment groove (201).

7. A cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection according to any one of claims 1-6, characterized in that, A guiding bending section (101) is provided at one end of the handle (1) located at the sampling brush head (5).

8. A cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection according to claim 6, characterized in that, The guiding bending section (101) includes multiple groups of guiding bending section blocks (102), and the multiple groups of guiding bending section blocks (102) are rotatably connected through a guiding bending joint (103).

9. A cervical and vaginal exfoliated cell sampling device for self-sampling HPV detection according to claim 1, characterized in that, One end of the sleeve plate (3) is provided with an opening, and the opening size is larger than that of the spherical head body (6). The other end of the sleeve plate (3) is fixedly provided with a sleeve plate (3). The sleeve plate (3) is slidably sleeved on the outer side of the handle (1). Finger sleeves (4) are fixedly provided at both ends of the surface of the sleeve plate (3).

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