Blood sample analyzer
By using suction and spitting parts with different capacity set in series and pre-built negative pressure technology in the blood sample analyzer, the problem that negative pressure in the sample tube affects sampling reliability is solved, and the combined detection of routine blood blood and red blood cell sedimentation rate is achieved, and the sample allocation accuracy and instrument reliability are improved.
Patent Information
- Application Number
- CN202410144736.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-31
- Publication Date
- 2025-08-01
AI Technical Summary
During the sampling process, due to the negative pressure in the sample tube, the liquid in the sampling module's pipeline may be reversed into the sample tube, causing sample contamination and affecting the reliability of sampling.
The first suction and second suction and spitting parts are arranged in series, with different capacity. The pre-built negative pressure value balances the pipeline pressure, combined with the red blood cell sedimentation rate detection module and the blood conventional detection module share the pipeline, and the sample is mixed/depolymerized with larger suiting and spitting parts, and the suiting and spitting parts with smaller capacity are accurately distributed.
Improve the accuracy of sample allocation and detection reliability, simplify the instrument structure, reduce costs, and reduce the possibility of sample contamination through pre-built negative pressure.
Smart Images
Figure CN120405159A_ABST
Abstract
Description
Technical Field
[0001] This application relates to the technical field of medical devices, and particularly to a blood sample analyzer. Background Art
[0002] A blood sample analyzer is a medical precision instrument that can be used to analyze and measure blood samples. A blood sample analyzer generally includes a sampling module and a detection module. The sampling module is used to aspirate samples from a sample tube, and the detection module is used to detect the samples aspirated by the sampling module.
[0003] When analyzing blood samples, generally a sample tube with a pre-applied negative pressure is used for blood sample collection. After the blood sample collection is completed, there is generally still some negative pressure remaining in the sample tube.
[0004] When the sampling module aspirates samples from the sample tube, affected by the negative pressure in the sample tube, some liquid in the pipeline of the sampling module may retreat back into the sample tube, contaminating the sample and thus affecting the reliability of sampling. Summary of the Invention
[0005] This application provides a blood sample analyzer to solve the technical problem in the prior art that, affected by the negative pressure in the sample tube, some liquid in the pipeline of the sampling module may retreat back into the sample tube, contaminating the sample and thus affecting the reliability of sampling.
[0006] To solve the above technical problem, a technical solution adopted by this application is: providing a blood sample analyzer, which includes: a first suction and discharge member, a second suction and discharge member, and a second pipeline. The first suction and discharge member is connected to the first end of the second suction and discharge member through the second pipeline, so that the first suction and discharge member and the second suction and discharge member are arranged in series, and the capacities of the first suction and discharge member and the second suction and discharge member are different; a sampling needle and a first pipeline. The sampling needle is connected to the second end of the second suction and discharge member through the first pipeline. The first suction and discharge member or the second suction and discharge member collects samples through the sampling needle; an erythrocyte sedimentation rate detection module provided on the first pipeline; a blood routine detection module. The one with the smaller capacity among the first suction and discharge member and the second suction and discharge member is used to allocate samples to the blood routine detection module and the erythrocyte sedimentation rate detection module, and the one with the larger capacity is used to mix / depolymerize the samples in the erythrocyte sedimentation rate detection module. Among them, at least one of the first suction and discharge member and the second suction and discharge member is used to pre-establish a negative pressure in the second pipeline so that the pre-established negative pressure value in the second pipeline meets a preset condition.
[0007] Further, the one with the larger capacity among the first suction and discharge member and the second suction and discharge member is used to pre-establish a negative pressure in the second pipeline so that the pre-established negative pressure value in the second pipeline meets a preset condition.
[0008] Further, the capacity of the larger one of the first suction / discharge member and the second suction / discharge member is greater than the sum of the capacities of the first pipeline and the second pipeline.
[0009] Further, the pre-established negative pressure value in the second pipeline is not lower than -40 kPa. When the first suction / discharge member or the second suction / discharge member collects a sample through a sampling needle, the total deformation amount of the sampling needle, the first pipeline, the second pipeline, the first suction / discharge member, and the second suction / discharge member does not exceed 4 μl.
[0010] Further, the volume range of the isolation gas column sucked by the sampling needle before sampling is: 4 - 10 μl.
[0011] Further, when the larger one of the first suction / discharge member and the second suction / discharge member is used to mix / depolymerize the sample in the erythrocyte sedimentation rate detection module, the smaller one of the first suction / discharge member and the second suction / discharge member also performs suction / discharge actions to perform additional perturbation on the mixing / depolymerization of the sample in the erythrocyte sedimentation rate detection module.
[0012] Further, when the smaller one of the first suction / discharge member and the second suction / discharge member is used for additional perturbation, the suction / discharge speed of the smaller one of the first suction / discharge member and the second suction / discharge member is greater than the suction / discharge speed of the larger one of the first suction / discharge member and the second suction / discharge member.
[0013] Further, the larger one of the first suction / discharge member and the second suction / discharge member is used to suck the diluent to clean the whole blood sample analyzer with the diluent.
[0014] Further, the blood sample analyzer further includes: a first cleaning module and a three-way valve. The first cleaning module is used to provide the diluent. The first suction / discharge member is connected to the first end of the three-way valve. The second end of the three-way valve is connected to the first cleaning module. The third end of the three-way valve is connected to the first end of the second suction / discharge member, wherein the capacity of the first suction / discharge member is greater than the capacity of the second suction / discharge member.
[0015] Further, the blood sample analyzer further includes a pressure detection unit and a control unit. The control unit is connected to the pressure detection unit, the first suction / discharge member, and the second suction / discharge member. When the sampling needle samples, the pressure detection unit is used to detect the pressure value in the first pipeline or the second pipeline; the control unit is used to: when it is confirmed that the pressure value is greater than the preset negative pressure value, control the larger one of the first suction / discharge member and the second suction / discharge member to push or reciprocate push-pull to form a preset pressure backflush on the sampling needle.
[0016] Advantages of the present application: Different from the prior art, in the blood sample analyzer of the present application, the first suction and discharge member is connected to the first end of the second suction and discharge member through the second pipeline, so that the first suction and discharge member and the second suction and discharge member are arranged in series. The capacities of the first suction and discharge member and the second suction and discharge member are different, and the combined detection of blood routine and erythrocyte sedimentation rate can be realized. The one with the smaller capacity in the first suction and discharge member and the second suction and discharge member is used to allocate samples for the blood routine detection module and the erythrocyte sedimentation rate detection module, so as to improve the accuracy of sample allocation, thereby improving the reliability of the detection of the blood sample analyzer. The one with the larger capacity is used to mix / depolymerize the samples in the erythrocyte sedimentation rate detection module. Due to the larger capacity, the samples in the erythrocyte sedimentation rate detection module can flow back and forth in the first pipeline without a peristaltic pump or through a separate driving member. Therefore, the structure of the blood sample analyzer is simplified and the cost is low. At least one of the first suction and discharge member and the second suction and discharge member is used to pre-establish a negative pressure in the second pipeline so that the pre-established negative pressure value in the second pipeline meets the preset conditions. When the sampling needle is sampling, due to the residual negative pressure in the test tube, the diluent in the pipeline may flow back into the test tube, thereby contaminating the sample. By pre-establishing a negative pressure in the pipeline, the negative pressure values in the first pipeline and the second pipeline can be balanced with the residual negative pressure in the test tube, thereby reducing the influence of the residual pressure on sampling. Description of the Drawings
[0017] Figure 1 It is a schematic structural diagram of an embodiment of a blood sample analyzer provided by the present application. Detailed Embodiments
[0018] In order to make the above objects, features and advantages of the present application more obvious and understandable, the following will describe the detailed embodiments of the present application in conjunction with the drawings. It can be understood that the specific embodiments described herein are only used to explain the present application, rather than limiting the present application. In addition, it should be noted that for the sake of description, only the parts related to the present application rather than all the structures are shown in the drawings. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present application.
[0019] The terms "first", "second", etc. in the present application are used to distinguish different objects, rather than to describe a specific order. In addition, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device that includes a series of steps or units is not limited to the listed steps or units, but optionally further includes steps or units not listed, or optionally further includes other steps or units inherent to these processes, methods, products or devices.
[0020] References to "embodiments" in this specification mean that the particular features, structures, or characteristics described in connection with the embodiments can be included in at least one embodiment of the present application. The phrase appears in various places in the specification and does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein can be combined with other embodiments.
[0021] The present application provides a blood sample analyzer that can perform a combined inspection of blood routine and erythrocyte sedimentation rate. The structure of the blood sample analyzer is simple and the cost is low. By pre-building negative pressure in the pipeline, the influence of the residual pressure in the test tube can be reduced, thereby improving the reliability of sampling.
[0022] Please refer to Figure 1 as shown Figure 1 FIG. 10 is a schematic structural diagram of an embodiment of the blood sample analyzer provided by the present application. Specifically, the blood sample analyzer 10 can be at least used for performing blood routine detection and erythrocyte sedimentation rate detection on a blood sample. Specifically, the blood sample analyzer 10 includes: a first suction and discharge member 11, a second suction and discharge member 12, a second pipeline T2, a sampling needle 14, a first pipeline T1, an erythrocyte sedimentation rate detection module 13, and a blood routine detection module (not shown in the figure).
[0023] Among them, the first suction and discharge member 11 is connected to the first end of the second suction and discharge member 12 through the second pipeline T2, so that the first suction and discharge member 11 and the second suction and discharge member 12 are arranged in series, and the capacities of the first suction and discharge member 11 and the second suction and discharge member 12 are different.
[0024] In Figure 1 the embodiment shown in FIG. 18, the capacity of the first suction and discharge member 11 is greater than that of the second suction and discharge member 12. In this case, the first suction and discharge member 11 can be used to suck a large sample. Usually, the volume of the large sample can exceed 130 ul. The second suction and discharge member 12 can be used to suck a small sample, and the accuracy of the second suction and discharge member 12 is greater than that of the first suction and discharge member 11. The capacity of the first suction and discharge member 11 can be not less than 2.5 ml, and the capacity of the second suction and discharge member 12 can be not more than 300 ul, so that the first suction and discharge member 11 can suck an enough amount of liquid, and the second suction and discharge member 12 has enough accuracy. The first suction and discharge member 11 with a large capacity is connected in series to the second suction and discharge member 12. In this way, the second suction and discharge member 12 and the pipeline of the blood sample analyzer 10 can be cleaned through the first suction and discharge member 11.
[0025] In other embodiments, the capacity of the first suction and discharge member 11 can also be less than that of the second suction and discharge member 12.
[0026] Such as Figure 1As shown, the second end of the second suction and discharge member 12 can be connected to the sampling needle 14 through the first pipeline T1, and the sampling needle 14 is used to collect samples. Specifically, the first suction and discharge member 11 or the second suction and discharge member 12 cooperates with the sampling needle 14 to collect samples.
[0027] The erythrocyte sedimentation rate detection module 13 is provided on the first pipeline T1. Specifically, the erythrocyte sedimentation rate detection module 13 includes a pipeline within a preset range in the first pipeline T1 and a detection component. The detection component is located outside the pipeline within the preset range and is used to detect the erythrocyte sedimentation rate through the blood sample in the pipeline within the preset range. In this way, the erythrocyte sedimentation rate detection module 13 does not need to be provided with an additional pipeline, but shares the pipeline with the blood routine detection module, simplifying the structure of the blood sample analyzer 10 and saving costs.
[0028] The first suction and discharge member 11 or the second suction and discharge member 12 can collect samples through the sampling needle 14. The one with a smaller capacity among the first suction and discharge member 11 and the second suction and discharge member 12 can be used to allocate samples to the blood routine detection module and the erythrocyte sedimentation rate detection module 13. Since the suction and discharge member with a smaller capacity has higher precision, allocating samples through the suction and discharge member with higher precision can reduce the error of sample allocation and improve the accuracy of sample detection.
[0029] The one with a larger capacity among the first suction and discharge member 11 and the second suction and discharge member 12 can be used to mix / disperse the samples in the erythrocyte sedimentation rate detection module 13. Due to the larger capacity, it can make the samples in the erythrocyte sedimentation rate detection module 13 flow back and forth in the first pipeline T1. In this application, sample mixing refers to the back-and-forth pulling / suction action when the sample standing time is less than 2 s, and sample dispersion refers to the back-and-forth pulling / suction action when the sample standing time is 1 - 60 s. Because of the time difference in the formation of rouleaux by red blood cells in different samples, the pulling speed during sample mixing / dispersion can be selected according to the type of sample.
[0030] Furthermore, at least one of the first suction and discharge member 11 and the second suction and discharge member 12 can be used to pre - establish a negative pressure in the second pipeline T2 so that the pre - established negative pressure value in the second pipeline T2 meets the preset conditions. When the sampling needle 14 is sampling, due to the residual negative pressure in the test tube, it may cause the diluent in the pipeline to flow back into the test tube, thereby contaminating the sample. By pre - establishing a negative pressure in the second pipeline T2, the negative pressure values in the first pipeline T1 and the second pipeline T2 can balance the residual negative pressure in the test tube, thereby reducing the influence of the residual pressure on sample aspiration.
[0031] The blood sample analyzer 10 in the above embodiments has a simple structure and low cost. The first suction and discharge member 11 and the second suction and discharge member 12 are arranged in series, enabling the combined detection of blood routine and erythrocyte sedimentation rate. Moreover, by pre-building negative pressure in the pipeline through at least one of the first suction and discharge member 11 and the second suction and discharge member 12, the influence of the residual pressure in the test tube can be reduced, and the reliability of sample sampling can be improved.
[0032] Optionally, the one with a larger capacity among the first suction and discharge member 11 and the second suction and discharge member 12 can be used to pre-build negative pressure for the second pipeline T2, so that the pre-built negative pressure value in the second pipeline T2 meets the preset conditions. By using the suction and discharge member with a larger capacity to pre-build negative pressure, the range of negative pressure construction can be expanded.
[0033] The suction and discharge member with a small capacity has high precision and can be used for sample distribution. In this way, the precision of sample distribution can be improved. The suction and discharge member with a large capacity can be used for sample collection. In this way, the sample collected at one time is sufficient to be distributed to multiple reaction pools of the blood routine detection module. The suction and discharge member with a large capacity can also be used to mix or depolymerize the sample in the erythrocyte sedimentation rate detection module 13, so that the sample in the erythrocyte sedimentation rate detection module 13 flows back and forth in the first pipeline T1, which is easy to operate and has low cost. In addition, the suction and discharge member with a large capacity can also be used to clean the blood sample analyzer 10. For specific details, please refer to the following introduction and will not be elaborated here.
[0034] Furthermore, the capacity of the one with a larger capacity among the first suction and discharge member 11 and the second suction and discharge member 12 is greater than the sum of the capacities of the first pipeline T1 and the second pipeline T2. In this way, the suction and discharge member with a larger capacity can pre-build sufficient negative pressure for the first pipeline T1 and the second pipeline T2. Moreover, when the suction and discharge member with a larger capacity among the first suction and discharge member 11 and the second suction and discharge member 12 is used to clean the pipeline, the entire pipeline can be cleaned with the diluent sucked at one time, reducing the cleaning time of the blood sample analyzer 10.
[0035] According to the size of the residual negative pressure in the test tube, the pre-built negative pressure value in the second pipeline T2 by the one with a larger capacity among the first suction and discharge member 11 and the second suction and discharge member 12 is not less than -40 kPa, so as to minimize the possibility of the diluent in the pipeline being sucked back when the sampling needle 14 samples.
[0036] When the residual negative pressure in the test tube exceeds -40 kPa, when the first suction and discharge member 11 or the second suction and discharge member 12 samples through the sampling needle 14, the total deformation of the sampling needle 14, the first pipeline T1, the second pipeline T2, the first suction and discharge member 11 and the second suction and discharge member 12 does not exceed 4 μl, so that the isolation air column in the sampling needle 14 and the diluent in the pipeline are not sucked out by the remaining negative pressure, thereby improving the accuracy of sample parameter detection.
[0037] Further, the volume range of the isolation air column aspirated by the sampling needle 14 before sampling is: 4 - 10 μl. For example, the volume of the isolation air column aspirated by the sampling needle 14 can be 4 μl, 6 μl, 7 μl, 9 μl, or 10 μl. The isolation air column within this volume range can balance the accuracy of sample collection and the influence of the diluent in the pipeline and the negative pressure in the test tube.
[0038] When the larger-capacity one of the first aspiration / dispensing member 11 and the second aspiration / dispensing member 12 is used to mix / depolymerize the sample in the erythrocyte sedimentation rate detection module 13, the smaller-capacity one of the first aspiration / dispensing member 11 and the second aspiration / dispensing member 12 can also perform aspiration / dispensing actions to perform additional perturbation on the mixing / depolymerization of the sample in the erythrocyte sedimentation rate detection module 13, thereby improving the effect of sample mixing / depolymerization.
[0039] Optionally, when the smaller-capacity one of the first aspiration / dispensing member 11 and the second aspiration / dispensing member 12 is used for additional perturbation, the aspiration / dispensing speed of the smaller-capacity one of the first aspiration / dispensing member 11 and the second aspiration / dispensing member 12 is greater than the aspiration / dispensing speed of the larger-capacity one of the first aspiration / dispensing member 11 and the second aspiration / dispensing member 12. In this way, the sample aspirated and dispensed by the larger-capacity aspiration / dispensing member can be more severely perturbed, improving the sample mixing / depolymerization effect.
[0040] Optionally, when the smaller-capacity aspiration / dispensing member is used for additional perturbation, its aspiration / dispensing speed can also be greater than the aspiration / dispensing speed of the larger-capacity aspiration / dispensing member. In this way, additional perturbation can also be performed on the sample during the mixing / depolymerization process, improving the mixing effect.
[0041] Further, the larger-capacity aspiration / dispensing member can also be used to clean the blood sample analyzer 10, realizing the one-time aspiration of the cleaning liquid during the whole-machine maintenance process and reducing the manual waiting time.
[0042] In some specific embodiments, the capacity of the first aspiration / dispensing member 11 is greater than the capacity of the second aspiration / dispensing member 12, that is, the larger-capacity aspiration / dispensing member is located at the end. In this way, the entire blood sample analyzer 10 can be cleaned by the larger-capacity aspiration / dispensing member.
[0043] Further, as Figure 1As shown, the blood sample analyzer 10 may further include: a first cleaning module 15 and a three-way valve LV01. The first cleaning module 15 is used to provide diluent. The first suction and discharge member 11 is connected to the first end of the three-way valve LV01. The second end of the three-way valve LV01 is connected to the first cleaning module 15, and the third end of the three-way valve LV01 is connected to the first end of the second suction and discharge member 12. When the first end and the second end of the three-way valve LV01 are communicated, the first suction and discharge member 11 can suck diluent from the first cleaning module 15. When the first end and the third end of the three-way valve LV01 are communicated, the first suction and discharge member 11 cleans the inner walls of the second pipeline T2, the second suction and discharge member 12, the first pipeline T1, and the sampling needle 14 with the diluent. In this way, the entire pipeline of the blood sample analyzer 10 can be cleaned by the first cleaning module 15 and the first suction and discharge member 11. The cleaning process is simple and the cleaning efficiency is relatively high.
[0044] Further, when performing maintenance cleaning on the blood sample analyzer 10, the one with a larger capacity among the first suction and discharge member 11 and the second suction and discharge member 12 can suck diluent from an external test tube through the sampling needle 14, and the one with a smaller capacity among the first suction and discharge member 11 and the second suction and discharge member 12 is configured to inject the diluent into the corresponding reaction pool in sequence to clean each reaction pool. Thus, the diluent during the whole machine maintenance process can be sucked at one time, reducing the cleaning time of the blood sample analyzer 10 and the waiting time of the operator.
[0045] Further, as Figure 1 shown, the blood sample analyzer 10 may further include a cleaning swab 20 and a second cleaning module (not marked in the figure). The cleaning swab 20 is sleeved around the sampling needle 14, and the second cleaning module is connected to the cleaning swab 20. The second cleaning module is used to cooperate with the cleaning swab 20 to clean the outer wall of the sampling needle 14.
[0046] Specifically, as Figure 1 shown, the second cleaning module includes a cleaning liquid providing module 21 and a power module 22. The cleaning liquid providing module 21 is connected to one end of the cleaning swab 20 through a two-way valve LV02, and the power module 22 is connected to the other end of the cleaning swab 20. The power module 22 sucks the cleaning liquid from the cleaning liquid providing module 21, so that the cleaning liquid of the cleaning liquid providing module 21 passes through the swab 20, thereby cleaning the outer wall of the sampling needle 14.
[0047] Further, as Figure 1 shown, the blood sample analyzer 10 may further include a pressure detection unit 18. When the sampling needle 14 performs sampling, the pressure detection unit 18 is used to detect the pressure value in the first pipeline T1 or the second pipeline T2.
[0048] During Figure 1In the illustrated embodiment, the pressure detection unit 18 is provided on the second pipeline T2. When the sampling needle 14 performs sampling, the pressure detection unit 18 is used to detect the pressure of the second pipeline T2. In other embodiments, the pressure detection unit 18 can also be provided on the first pipeline T1. When the sampling needle 14 performs sampling, the pressure detection unit 18 is used to detect the pressure of the first pipeline T1. When the negative pressure detected by the pressure detection unit 18 is relatively large, it can be prompted that the sampling needle 14 has abnormal sample suction. In this case, a large-capacity suction and discharge member can be used to perform rapid reciprocating pushing and pulling to form a certain pressure to backflush the sampling needle 14, thereby eliminating the needle clogging fault of the sampling needle 14.
[0049] Specifically, the blood sample analyzer 10 further includes a control unit (not shown in the figure). The control unit is connected to the pressure detection unit 18, the first suction and discharge member 11, and the second suction and discharge member 12.
[0050] The control unit is configured to: when it is confirmed that the pressure value detected by the pressure detection unit 18 is greater than a preset negative pressure value, control the larger-capacity one of the first suction and discharge member 11 and the second suction and discharge member 12 to perform pushing or reciprocating pushing and pulling to form a preset pressure to backflush the sampling needle 14. During the sample suction process of the sampling needle 14, if the sampling needle 14 is clogged by foreign objects, impurities or debris, the negative pressure monitored by the pressure detection unit 18 will increase significantly. The blood sample analyzer 10 can report a fault of abnormal sample suction / insufficient sample suction. The blood sample analyzer 10 can introduce a fault self-elimination design of intelligent diagnosis. When a fault of abnormal sample suction / insufficient sample suction is monitored, it can control the large-capacity suction and discharge member to quickly push or reciprocate push and pull to form a certain size of pressure to backflush the sampling needle 14. Usually, the pressure should be greater than or equal to 150 kPa to achieve self-elimination of the needle clogging fault of the sampling needle 14.
[0051] In the blood sample analyzer 10 provided by the present application, the first suction and discharge member 11 and the second suction and discharge member 12 are connected in series, which can realize the combined detection of blood routine and erythrocyte sedimentation rate. Moreover, by pre-building a negative pressure in the pipeline by at least one of the first suction and discharge member 11 and the second suction and discharge member 12, the influence of the residual pressure in the test tube can be reduced, and the reliability of sample sampling can be improved. The large-capacity suction and discharge member can also be used to mix or depolymerize the sample in the erythrocyte sedimentation rate detection module 13. Due to its large capacity, it can make the sample in the erythrocyte sedimentation rate detection module 13 flow back and forth in the first pipeline T1 without a peristaltic pump or a separate driving member. Therefore, the structure of the blood sample analyzer 10 is simplified, the cost is low, and it has strong practicability.
[0052] The above are only embodiments of the present application, and do not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made by using the content of the specification and drawings of the present application, or directly or indirectly applied in other related technical fields, shall be similarly included in the patent protection scope of the present application.
Claims
1. A blood sample analyzer, characterized in that, The blood sample analyzer includes: A first suction and discharge member, a second suction and discharge member, and a second pipeline. The first suction and discharge member is connected to the first end of the second suction and discharge member through the second pipeline, so that the first suction and discharge member and the second suction and discharge member are arranged in series, and the capacities of the first suction and discharge member and the second suction and discharge member are different; A sampling needle and a first pipeline. The sampling needle is connected to the second end of the second suction and discharge member through the first pipeline. The first suction and discharge member or the second suction and discharge member collects samples through the sampling needle; An erythrocyte sedimentation rate detection module, which is arranged on the first pipeline; A blood routine detection module. The one with the smaller capacity among the first suction and discharge member and the second suction and discharge member is used to allocate samples to the blood routine detection module and the erythrocyte sedimentation rate detection module, and the one with the larger capacity is used to mix / depolymerize the samples in the erythrocyte sedimentation rate detection module, Wherein, at least one of the first suction and discharge member and the second suction and discharge member is used to pre - establish a negative pressure in the second pipeline, so that the pre - established negative pressure value in the second pipeline meets a preset condition.
2. The blood sample analyzer according to claim 1, characterized in that, The one with the larger capacity among the first suction and discharge member and the second suction and discharge member is used to pre - establish a negative pressure in the second pipeline, so that the pre - established negative pressure value in the second pipeline meets a preset condition.
3. The blood sample analyzer according to claim 2, wherein, The capacity of the one with the larger capacity among the first suction and discharge member and the second suction and discharge member is greater than the sum of the capacities of the first pipeline and the second pipeline.
4. The blood sample analyzer according to claim 1, characterized in that, The pre - established negative pressure value in the second pipeline is not lower than - 40 kPa. When the first suction and discharge member or the second suction and discharge member collects samples through the sampling needle, the total deformation amount of the sampling needle, the first pipeline, the second pipeline, the first suction and discharge member, and the second suction and discharge member does not exceed 4 ul.
5. The blood sample analyzer according to claim 1, wherein The volume range of the isolation air column sucked by the sampling needle before sampling is: 4 - 10 ul.
6. The blood sample analyzer according to claim 1, characterized in that, When the one with the larger capacity among the first suction and discharge member and the second suction and discharge member is used to mix / depolymerize the samples in the erythrocyte sedimentation rate detection module, the one with the smaller capacity among the first suction and discharge member and the second suction and discharge member also performs suction and discharge actions to perform additional disturbance on the mixing / depolymerization of the samples in the erythrocyte sedimentation rate detection module.
7. The blood sample analyzer according to claim 6, wherein When the one with the smaller capacity among the first suction and discharge member and the second suction and discharge member is used for the additional disturbance, the suction and discharge speed of the one with the smaller capacity among the first suction and discharge member and the second suction and discharge member is greater than the suction and discharge speed of the one with the larger capacity among the first suction and discharge member and the second suction and discharge member.
8. The blood sample analyzer according to claim 1, wherein, The one with the larger capacity among the first suction and discharge member and the second suction and discharge member is used to suck the diluent to clean the whole blood sample analyzer through the diluent.
9. The blood sample analyzer according to claim 1, wherein, The blood sample analyzer further includes: a first cleaning module and a three - way valve. The first cleaning module is used to provide diluent, The first suction and discharge member is connected to the first end of the three - way valve, the second end of the three - way valve is connected to the first cleaning module, and the third end of the three - way valve is connected to the first end of the second suction and discharge member. Wherein, the capacity of the first suction and discharge member is greater than the capacity of the second suction and discharge member.
10. The blood sample analyzer according to claim 1, characterized in that, The blood sample analyzer further includes a pressure detection unit and a control unit. The control unit is connected to the pressure detection unit, the first suction and discharge member, and the second suction and discharge member. When the sampling needle performs sampling, the pressure detection unit is used to detect the pressure value in the first pipeline or the second pipeline. The control unit is configured to: when it is confirmed that the pressure value is greater than a preset negative pressure value, control the one with the larger capacity among the first suction and discharge member and the second suction and discharge member to perform pushing or reciprocating pushing and pulling, so as to form a preset pressure to backflush the sampling needle.