Anti-aging composition for strengthening the dermal support network and use thereof

Abstract

This invention relates to an anti-aging composition for strengthening the skin's support network and its application, comprising the following components: Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside, wherein the weight ratio of Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside is (0.1-5):(0.01-5):(0.1-10):(0.01-2):(0.001-0.1). The composition of this invention synergistically strengthens the skin's support network by promoting the growth of two core structural proteins and three molecular-level binders, achieving a comprehensive improvement in skin elasticity and firmness. It is gentle and non-irritating, suitable for people with sensitive skin.

Description

Technical Field

[0001] This invention relates to the technical field of cosmetics, and more specifically to an anti-aging composition that strengthens the skin's support network and its application. Background Technology

[0002] The essence of skin aging is the reduction in the number of fibroblasts, collagen loss, and disordered elastin fiber structure, leading to a decline in skin barrier function and causing wrinkles, sagging, and other problems. Collagen, as the main structural framework of the skin (accounting for more than 70% of the dry weight of the dermis), leads to a decrease in the tensile strength of the skin due to its loss, causing wrinkles and sagging. The degradation of the elastin fiber network causes the skin to lose its elasticity, exacerbating sagging. Core proteoglycans, as "precision regulators" of collagen fibers, directly disrupt the orderly arrangement of collagen fibers and weaken the dermal matrix's resistance to deformation when their deficiency occurs. Peronein, as the "assembly hub" of elastic fibers, has reduced expression, causing elastin to be unable to stably anchor to the microfiber scaffold, resulting in the collapse of the elastic network structure and impaired repair function. Lysyl oxidase (LOX), as the "cross-linking catalytic center" of the extracellular matrix, has reduced activity, which interferes with the covalent cross-linking of collagen / elastin, leading to the loosening and disintegration of the supporting structure. The synergistic decay and interaction imbalance of these five types of proteins disrupt the multi-level defense system of "collagen skeleton strength - elastic network toughness - fiber orderliness - structural integration - molecular stability", which together constitute the molecular basis for the collapse of the skin support network, ultimately manifesting as the loss of skin elasticity and firmness.

[0003] Current anti-aging technologies mainly rely on bioactive ingredients (such as retinol and peptides) and plant extracts. However, the former suffers from poor stability and strong irritation (e.g., retinol is easily oxidized and can cause discomfort in sensitive skin), while the latter's effectiveness is limited due to the low transdermal absorption rate of natural ingredients. Although emerging technologies (such as gene regulation and exosomes) are gradually gaining popularity, their application is still limited by cost, regulations, and technological maturity. Furthermore, people with sensitive skin are more prone to inflammatory aging due to damaged skin barriers, creating an urgent need for gentle and effective anti-aging solutions. Summary of the Invention

[0004] The purpose of this invention is to overcome the shortcomings of the prior art and provide an anti-aging composition that strengthens the skin's support network and its application.

[0005] To achieve the above objectives, the technical solution adopted by the present invention is as follows:

[0006] In a first aspect, the present invention provides an anti-aging composition for strengthening the skin's support network, comprising the following components: Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside, wherein the weight ratio of Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside is (0.1-5):(0.01-5):(0.1-10):(0.01-2):(0.001-0.1).

[0007] The mechanism of action of the components in the composition of this invention is as follows: Camellia chrysantha flower extract is rich in tea polyphenols, flavonol glycosides, and proanthocyanidins, which significantly improve skin roughness and photoaging damage by powerfully scavenging free radicals through antioxidant activity; the saffron extract is rich in flavonoids and polyphenols, which have a strong anti-inflammatory effect and can effectively soothe skin redness and discomfort; the camellia seed oil contains a high concentration of oleic acid, vitamin E, and squalene, which can penetrate deeply by mimicking the structure of sebum, enhance water-locking ability, neutralize free radicals, repair stratum corneum damage, and delay the formation of wrinkles; the tranexamic acid is a multifunctional skin care ingredient that achieves whitening and soothing effects by powerfully inhibiting tyrosinase activity and blocking inflammatory factors, and reduces premature aging symptoms caused by inflammation; the epigallocatechin gallate glucoside, a polyphenolic compound derived from green tea, has an antioxidant strength 25 times that of vitamin C, which slows down skin aging by inhibiting matrix metalloproteinase activity and blocking collagen degradation.

[0008] Preferably, the weight ratio of the camellia flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside is (0.5-3):(0.1-0.5):(1-3):(0.05-0.5):(0.01-0.05).

[0009] Preferably, the weight ratio of the camellia flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside is (1-2):(0.2-0.3):(2-3):(0.1-0.2):(0.02-0.03).

[0010] Preferably, the total mass of the camellia flower extract and the saffron extract accounts for 35-45 wt% of the total mass of the anti-aging composition.

[0011] In a second aspect, the present invention provides the application of the anti-aging composition for strengthening the skin support network in the first aspect in the preparation of cosmetics.

[0012] Preferably, the cosmetic is a toner, lotion, cream, mask, serum, or spray, and the amount of the anti-aging composition added is 1%-5% of the total weight of the cosmetic.

[0013] Thirdly, the present invention provides an essence comprising the following ingredients by weight percentage: 1%-5% of the anti-aging composition for strengthening the skin support network according to any one of claims 1-4, 0.05%-0.5% of a thickener, 0.5%-10% of a moisturizer, 0.5%-3% of a preservative, and 0.01%-0.3% of a pH adjuster, with the balance being deionized water.

[0014] Preferably, the thickener includes at least one of xanthan gum, carbomer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, ammonium acryloyldimethyl taurate / VP copolymer, and sclerotium gum.

[0015] Preferably, the moisturizer comprises at least one of allantoin, betaine, β-glucan, trehalose, caprylyl glycol, dipropylene glycol, D-panthenol, sodium hyaluronate, 1,2-butanediol, glycerin, budding stalk polysaccharide, and ceramide.

[0016] Preferably, the pH adjuster includes at least one of arginine, tromethamine, and disodium EDTA.

[0017] Preferably, the preservative includes at least one of 1,3-propanediol, 1,2-hexanediol, and p-hydroxyacetophenone.

[0018] Fourthly, the present invention provides a method for preparing the essence described in the third aspect, comprising the following steps:

[0019] S1. Mix the humectant, thickener and part of the deionized water, homogenize at 75-85℃, then add the preservative and stir evenly to obtain the mixture.

[0020] S2. When the temperature of the mixture in S1 drops to 35-45℃, add the components of the anti-aging composition that strengthens the skin support network and the remaining deionized water, stir evenly, and finally add a pH adjuster to adjust the pH to obtain the essence.

[0021] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0022] The anti-aging composition of the present invention comprises Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside. Their synergistic effect strengthens the skin support network by promoting the growth of two core structural proteins and three molecular-level binders in the skin, thereby achieving a comprehensive improvement in skin elasticity and firmness. It is also gentle and non-irritating, making it suitable for people with sensitive skin. Detailed Implementation

[0023] To better illustrate the purpose, technical solution, and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0024] The sources of the raw materials used in the following examples and comparative examples are as follows:

[0025] Camellia chrysantha flower extract: manufactured by Ximuyuan (Xiamen) Biotechnology Co., Ltd.;

[0026] Tranexamic acid: manufactured by Shaanxi Wanhe Pharmaceutical Co., Ltd.;

[0027] Camellia seed oil: manufactured by Biospectrum, a South Korean company;

[0028] Saffron extract: manufactured by Guangzhou Youran Biotechnology Co., Ltd.

[0029] Epigallocatechin gallate glucoside: manufactured by Givaudan, Switzerland.

[0030] Unless otherwise specified, all other materials and reagents used in the examples are commercially available.

[0031] Examples 1-7 and Comparative Examples 1-7

[0032] The compositional components of the anti-aging compositions of Examples 1-7 and Comparative Examples 1-7 are shown in Table 1.

[0033] The preparation methods of the anti-aging compositions of Examples 1-7 and Comparative Examples 1-7 include the following steps:

[0034] The anti-aging composition is obtained by stirring and mixing the components at a speed of 300 rpm.

[0035] Table 1 shows the weight ratio of each component and the mass fraction of Camellia japonica extract and saffron extract in each anti-aging composition.

[0036]

[0037] Test Example 1: Test on the effect of anti-aging composition on promoting the synthesis of two core structural proteins and three major adhesive proteins in the dermis

[0038] I. Experimental Materials

[0039] 1. Cell line: Human dermal fibroblast HDF (Catalog No. PC-202h, Wuhan Saisuo Biotechnology Co., Ltd.)

[0040] 2. Culture medium: DMEM high-glucose culture medium containing 10% fetal bovine serum (Gibco)

[0041] 3. Inducing agent: PBS buffer containing 100 μM hydrogen peroxide

[0042] 4. Test kit:

[0043] Human type I collagen (Col I) ELISA kit (catalog number ml057630, Shanghai Enzyme-Linked Biotechnology Co., Ltd.) Human elastin ELISA kit (catalog number ml038411, Shanghai Enzyme-Linked Biotechnology Co., Ltd.)

[0044] Human Core Proteoglycan (DCN) ELISA Kit (Catalog No. ml105251, Shanghai Enzyme-Linked Biotechnology)

[0045] Human Aging Key Protein 1 (FBLN1) ELISA Kit (Catalog No. ml037827, Shanghai Enzyme-Linked Biotechnology)

[0046] Human Lysyl Oxidase (LOX) ELISA Kit (Catalog No. ml105166, Shanghai Enzyme-Linked Biotechnology)

[0047] II. Test Conditions

[0048] The incubator parameters were set to temperature 37±1℃, humidity 90±5%, and carbon dioxide concentration 5±1%.

[0049] III. Test Steps

[0050] 1. Cell inoculation

[0051] Human dermal fibroblasts with HDF were injected at a dose of 1.5 × 10⁻⁶. 5 The cells were seeded at a density of 100 cells / mL into 12-well cell culture plates, and 1 mL of DMEM high-glucose medium (Gibco) containing 10% fetal bovine serum was added to each well. The culture plates were placed in an incubator with pre-set conditions and incubated at 37°C and 5% CO2 for 24 hours.

[0052] 2. Cell induction

[0053] After 24 hours of incubation, discard the culture medium in the culture plate. Add pre-prepared PBS buffer containing 100 μM hydrogen peroxide and treat the cells in this solution for 30 minutes. After treatment, discard the PBS buffer containing hydrogen peroxide. Gently wash the culture plate three times with PBS buffer to remove residual hydrogen peroxide.

[0054] 3. Sample processing

[0055] For the blank control group, three parallel wells were set up, and 1 mL of DMEM high glucose culture medium containing 10% fetal bovine serum was added to each well.

[0056] For each sample group, three parallel wells were set up, and an equal volume of DMEM high-glucose culture medium containing 10% fetal bovine serum and 0.05 wt% of the anti-aging composition of each group was added to each well. After sample administration, the culture plates of each group were put back into the incubator and cultured for 24 hours at 37°C and 5% CO2.

[0057] 4. Collection of supernatant

[0058] After 24 hours of culture, remove the culture plates from the incubator, collect the cells, and discard the supernatant. Lyse the cells with RIPA lysis buffer (Shanghai Merck, V900854) containing protease inhibitors. Centrifuge the lysed samples at 12000g for 5 minutes, collect the supernatant, and store it below 4℃ for subsequent component content analysis.

[0059] 5. Component content detection

[0060] Type I collagen content detection: Follow the instructions of the human type I collagen (Col I) ELISA kit (catalog number ml057630, Shanghai Enzyme-Linked Biotechnology). Take equal amounts of cell culture supernatant from the blank control group and the sample group, and add them to the corresponding reaction wells of the kit. After incubation, washing, and color development, measure the absorbance value at a specific wavelength using an ELISA reader. Calculate the type I collagen content of each group based on the standard curve.

[0061] Elastin content detection: According to the instructions of the human elastin ELISA kit (catalog number ml038411, Shanghai Enzyme-Linked Biotechnology), equal amounts of cell culture supernatant from the blank control group and the sample group were taken for detection. The elastin content of each group was obtained by strictly following the operation steps of the kit.

[0062] Core proteoglycan content detection: Human core proteoglycan (DCN) ELISA kit (catalog number ml105251, Shanghai Enzyme-Linked Biotechnology) was used to detect the content of core proteoglycan in the cell culture supernatant of the blank control group and the sample group by strictly following the kit operation procedure.

[0063] Peroneal protein content detection: The human aging key protein 1 (FBLN1) ELISA kit (catalog number ml037827, Shanghai Enzyme-Linked Biotechnology) was used for detection. Equal amounts of cell culture supernatant from the blank control group and the sample group were used for measurement. The peroneal protein content was calculated by strictly following the kit operation procedure.

[0064] Lysyl oxidase content detection: Human lysyl oxidase (LOX) ELISA kit (catalog number ml105166, Shanghai Enzyme-Linked Biotechnology) was used to detect the lysyl oxidase content in equal volumes of cell culture supernatant from the blank control group and the sample group. The kit operation procedure was strictly followed to obtain the lysyl oxidase content in each group.

[0065] IV. Calculation of the anti-aging ability of anti-aging compositions

[0066] The anti-aging ability of the anti-aging composition was evaluated by calculating the increase rates of type I collagen, elastin, core proteoglycan, peroneal protein, and lysyl oxidase using the following formulas:

[0067] Increase rate of type I collagen = (Type I collagen content) 样品组 Type I collagen content 对照组 )×100%-1;

[0068] Elastin increase rate = (Elastin content) 样品组 / Elastin content 对照组 )×100%-1;

[0069] Core proteoglycan increase rate = (core proteoglycan content) 样品组 / Core proteoglycan content 对照组 )×100%-1;

[0070] Peroneal protein increase rate = (peroneal protein content) 样品组 / Fibrin content 对照组 )×100%-1;

[0071] Increase rate of lysyl oxidase = (lysyl oxidase content) 样品组 / Lysyl oxidase content 对照组 ()×100%-1. Data is shown in Table 2.

[0072] Table 2. Experimental data on the anti-aging ability of the anti-aging compositions in each group.

[0073]

[0074]

[0075] Collagen and elastin are the two core structural proteins of the skin: collagen acts as the skin's "steel skeleton," forming a mesh-like fibrous framework that provides tensile strength and support; elastin forms an elastic fiber network, supporting the collagen skeleton and providing instantaneous rebound. Core proteoglycans, peroneal proteins, and lysyl oxidase act as three molecular-level binders, strengthening the skin's support network: core proteoglycans encapsulate collagen fibers, regulating their orderly arrangement and diameter uniformity, thus enhancing tensile strength; peroneal proteins anchor elastin and microfibrils, weaving a tight elastic fiber network, preventing elastic fiber breakage and dispersion, and enhancing network structural stability; lysyl oxidase catalyzes the cross-linking reaction between collagen and elastin, forming covalent bond "welding points," strengthening the collagen-elastin complex structure, and resisting enzymatic and mechanical damage.

[0076] As can be seen from the data in Table 2 of Example 1 and Comparative Examples 1-2, when the weight ratio of Camellia japonica flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside in the composition is not in the range of (0.1-5):(0.01-5):(0.1-10):(0.01-2):(0.001-0.1), the increase rate of each protein is significantly reduced.

[0077] As shown in Table 2, the composition of Example 1, which uses five components—Camellia japonica flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside—significantly promotes the production of type I collagen, elastin, core proteoglycans, peroneal protein, and lysine oxidase. This indicates that the five components have a synergistic effect to enhance the anti-aging effect of the composition.

[0078] As can be seen from the data in Examples 1 and 4-7 in Table 2, when the weight ratio of Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside is (1-2):(0.2-0.3):(2-3):(0.1-0.2):(0.02-0.03) and the total mass of the Camellia chrysantha flower extract and saffron extract accounts for 35-45 wt% of the total mass of the anti-aging composition, the composition has a better effect on promoting protein production.

[0079] Application Example 1-7 and Comparative Application Example 1-7

[0080] The compositions of Examples 1-7 and Comparative Examples 1-7 were added to the serum at a concentration of 3 wt% to obtain the serums of Application Examples 1-7 and Comparative Application Examples 1-7. The formulations are shown in Table 3.

[0081] The preparation methods of the serums used in Application Examples 1-7 and Comparative Application Examples 1-7 include the following steps:

[0082] S1. Mix the humectant, thickener and 1 / 2 volume of deionized water, and homogenize at 80°C to obtain a mixture;

[0083] S2. When the temperature of the mixture in S1 drops to 60°C, add the preservative. When the temperature of the system drops to 40°C, add all the components in the composition and the remaining deionized water, stir evenly, and finally add the pH adjuster to adjust the pH to 6 to obtain the essence.

[0084] Table 3. Serum formulations for Application Examples 1-7 and Comparative Application Examples 1-7

[0085]

[0086]

[0087] Comparative Application Example 8

[0088] Compared to Application Example 8, the serum does not contain an anti-aging composition that strengthens the skin's support network. Instead, it uses an equal amount of deionized water instead of the composition, and the preparation method is the same as in Application Example 1.

[0089] Test Example 2: Human Patch Test of Serum

[0090] Thirty volunteers were recruited, 15 men and 15 women, aged 20-50 years. A closed patch test method was used. Equal volumes (0.020 mL-0.025 mL) of test samples (the serums prepared in Application Examples 1-7 and Control Examples 1-8) were placed in a specific patch applicator. The patch was then applied to the volunteers' arms with hypoallergenic adhesive tape, with nine samples applied to each arm. The patches were gently pressed to ensure even application to the skin and left on for 24 hours. After 24 hours, the patch applicator was removed, and skin reactions were observed and recorded at 0.5 hours, 24 hours, and 48 hours. The severity of adverse skin reactions is shown in Table 4 below.

[0091] Table 4. Adverse reaction levels of the skin

[0092]

[0093] After testing, the serums provided in Application Examples 1-7 and Comparative Application Examples 1-8 all showed negative reactions after human patch testing, indicating that they are safe and non-irritating to human skin.

[0094] Test Example 3: Anti-aging efficacy test of serum on the human body

[0095] 1. Experimental basis

[0096] The human efficacy evaluation test method shall be followed in accordance with the "Technical Specifications for Cosmetic Safety" (2015 edition).

[0097] 2. Subject selection

[0098] Inclusion criteria: We are recruiting Asian adult female volunteers aged 45-60 who meet the following conditions:

[0099] a) Clinical assessment indicates skin laxity (grades I-III according to clinical grading standards);

[0100] b) A self-reported history of skin allergies (confirmed by a dermatologist);

[0101] c) No history of serious systemic diseases or skin diseases.

[0102] Exclusion criteria: pregnant / lactating women, individuals with severe allergies, and individuals who have participated in other clinical trials within the past 3 months.

[0103] Number of participants: A total of 90 qualified volunteers were included and divided into 15 groups of 6 people each, using a random number table method.

[0104] 3. Sample application method

[0105] Test samples: serums prepared in Application Examples 1-7 and Comparative Application Examples 1-8 (double-blind method numbering), wherein the serum prepared in Comparative Application Example 8 served as the blank control group, and the other application examples and comparative application examples served as the sample groups.

[0106] How to use: After cleansing in the morning and evening, volunteers should take 1mL of the sample and apply it evenly to the entire face, gently massaging until fully absorbed.

[0107] 4. Testing Cycle and Process

[0108] Test period: 28 days (D0 to D) 28 ).

[0109] Visiting times: at D0 (baseline period) and D... 28 (At the end of the test) Instrument testing will be conducted.

[0110] Preparation before testing:

[0111] a) After the participants arrived, they used a uniform, non-irritating facial cleanser to clean their faces;

[0112] b) Rest for 30 minutes in a constant temperature and humidity environment (temperature 21±1℃, humidity 50±10%);

[0113] c) Keep your eyes closed and relax during the test to avoid facial expressions and movements that may interfere with the process.

[0114] 5. Testing Instruments and Parameters

[0115] Instrument: Cutometer (MPA580, Courage and Khazaka, Germany) was used for elasticity testing.

[0116] Measurement area: cheek (avoiding the periorbital and perilipal areas).

[0117] Operating procedures:

[0118] Calibrate the instrument to standard parameters; fix the probe pressure and measurement time; repeat the measurement three times at the same location and take the average value.

[0119] The skin tightening effect is represented by the improvement in the firmness F4 value, and the skin elasticity enhancement effect is represented by the improvement in the elasticity parameter R2 value, as shown in the following formula:

[0120] F4 value improvement rate = (F4 T0 -F4 T28 ) / F4 T0×100%;

[0121] R² improvement rate = (R²) T0 -R2 T28 ) / R2 T0 ×100%. Data is shown in Table 5.

[0122] Table 5. Results of human efficacy tests for each group of serums.

[0123] sample F4 value improvement rate / % R2 improvement rate / % Application Example 1 24.8 28.6 Application Example 2 23.2 27.5 Application Example 3 19.1 25.3 Application Example 4 18.7 25.6 Application Example 5 17.3 21.5 Application Example 6 16.9 20.8 Application Example 7 20.6 26.9 Comparative Application Example 1 3.4 4.6 Comparative Application Example 2 5.8 8.6 Comparative Application Example 3 2.6 2.8 Comparative Application Example 4 7.7 9.9 Comparative Application Example 5 5.1 7.7 Comparative Application Example 6 6.4 9.0 Comparative Application Example 7 4.6 6.8 Comparative application example 8 (blank control group) 0.6 0.3

[0124] F4 (Firmness) is a comprehensive parameter reflecting the skin's resilience and firmness; a higher value indicates greater firmness. R2 (Elasticity) represents the ratio of the skin's rebound amount to its maximum stretch when there is no negative pressure; a higher value indicates better elasticity.

[0125] As can be seen from the data in Application Example 1 and Comparative Application Examples 1-2 in Table 4, if the weight ratio of Camellia japonica flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside in the essence composition is not within the range of (0.1-5):(0.01-5):(0.1-10):(0.01-2):(0.001-0.1), the skin firmness and elasticity are significantly reduced.

[0126] As can be seen from the data in Application Example 1 and Comparative Application Examples 3-7 in Table 4, the composition of Example 1, which uses five ingredients including Camellia japonica flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside, has a significantly improved effect on enhancing skin elasticity and improving skin firmness compared to the compositions of Comparative Examples 3-7. This indicates that the anti-aging composition of the present invention synergistically strengthens the skin support network, thereby achieving a comprehensive improvement in skin elasticity and firmness.

[0127] Based on the data from Application Examples 1-7, it can be seen that when the weight ratio of Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside is (1-2):(0.2-0.3):(2-3):(0.1-0.2):(0.02-0.03), and the total mass of the Camellia chrysantha flower extract and saffron extract accounts for 35-45 wt% of the total mass of the anti-aging composition, the composition exhibits better anti-aging properties.

[0128] In summary, the anti-aging composition of the present invention, through the synergistic effect of five components—Camellia japonica flower extract, saffron extract, camellia seed oil, tranexamic acid, and epigallocatechin gallate glucoside—strengthens the skin's support network by promoting the growth of two core structural proteins and three molecular-level binders, thereby achieving a comprehensive improvement in skin elasticity and firmness. Furthermore, it is gentle and non-irritating, making it suitable for people with sensitive skin.

[0129] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. An anti-aging composition that strengthens the skin's support network, characterized in that, It is composed of the following components: Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside, wherein the weight ratio of Camellia chrysantha flower extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside is (0.1-5):(0.01-5):(0.1-10):(0.01-2):(0.001-0.1).

2. The anti-aging composition for strengthening the skin support network as described in claim 1, characterized in that, The weight ratio of the golden camellia flower extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside is (0.5-3):(0.1-0.5):(1-3):(0.05-0.5):(0.01-0.05).

3. The anti-aging composition for strengthening the skin support network as described in claim 1, characterized in that, The weight ratio of the golden camellia flower extract, saffron extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside is (1-2):(0.2-0.3):(2-3):(0.1-0.2):(0.02-0.03).

4. The anti-aging composition for strengthening the skin support network as described in claim 1, characterized in that, The total mass of the camellia flower extract and saffron extract accounts for 35-45 wt% of the total mass of the anti-aging composition.

5. The use of the anti-aging composition for strengthening the skin support network according to any one of claims 1-4 in the preparation of cosmetics.

6. The application of the anti-aging composition for strengthening the skin support network as described in claim 5 in the preparation of cosmetics, characterized in that, The cosmetic is a toner, lotion, cream, mask, serum, or spray, and the amount of the anti-aging composition added is 1%-5% of the total weight of the cosmetic.

7. An essence, characterized in that, The ingredients comprise the following ingredients by weight percentage: 1%-5% of the anti-aging composition for strengthening the skin support network according to any one of claims 1-4, 0.05%-0.5% of thickener, 0.5%-10% of moisturizer, 0.5%-3% of preservative and 0.01%-0.3% of pH adjuster, with the balance being deionized water.

8. The essence as described in claim 7, characterized in that, The raw material is selected from at least one of (a)-(d): (a) The thickener comprises at least one of xanthan gum, carbomer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, ammonium acryloyldimethyl taurate / VP copolymer and sclerotium gum; (b) The moisturizing agent comprises at least one of allantoin, betaine, β-glucan, trehalose, caprylyl glycol, dipropylene glycol, D-panthenol, sodium hyaluronate, 1,2-butanediol, glycerin, budding stalk polysaccharide and ceramide; (c) The pH adjuster includes at least one of arginine, tromethamine, and disodium EDTA; (d) The preservative is a composition of 1,3-propanediol, 1,2-hexanediol and p-hydroxyacetophenone.

9. The method for preparing the essence according to claim 8, characterized in that, Includes the following steps: S1. Mix the humectant, thickener and part of the deionized water, homogenize at 75-85℃, then add the preservative and stir evenly to obtain the mixture. S2. When the temperature of the mixture in S1 drops to 35-45℃, add the components of the anti-aging composition that strengthens the skin support network and the remaining deionized water, stir evenly, and finally add a pH adjuster to adjust the pH to obtain the essence.

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