Application of lycium barbarum glycopeptide in preparation of medicine for preventing or treating senile ossification

By using wolfberry glycopeptide to increase femoral hardness and promote osteoblast production and inhibit osteoclasts, the shortcomings of the treatment of ossification in the middle-aged and elderly people in the prior art are solved, and effective drug solutions are provided.

CN120420403APending Publication Date: 2025-08-05FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE +1
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Patent Information

Application Number
CN202510532483.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-25
Publication Date
2025-08-05

AI Technical Summary

Technical Problem

In the prior art, there is a lack of efficient, low-toxic and inexpensive drugs for the treatment of senile ossification, and the therapeutic effect of modern medicine on bone aging is inaccurate, with adverse reactions and high costs.

Method used

Lycium barbarum glycopeptide is used as the only active ingredient to promote osteoblast production and inhibit osteoclasts by increasing femoral hardness, alleviating calcium loss in bone tissue, and improving bone formation rate, promoting osteoblast production and inhibiting osteoclasts. It is prepared into various pharmaceutical dosage forms for preventing or treating senile ossification.

Benefits of technology

Lycium barbarum glycopeptide can effectively improve the hindlimb motor ability and trabecular bone condition in elderly mice, improve bone formation rate, and alleviate calcium loss in bone tissue, provide a more reliable treatment option for elderly ossification, and has important social and economic value.

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to application of lycium barbarum glycopeptide in preparation of a medicine for preventing or treating senile ossification. The experimental results show that the wolfberry glycopeptide can improve the posterior limb movement ability and the bone trabecula condition of old mice by increasing the femoral hardness, relieving the bone tissue calcium loss condition, improving the bone formation rate, promoting osteoblasts and inhibiting osteoclasts, so that the effect of treating bone aging is achieved. As a traditional Chinese medicinal material extraction product, the lycium barbarum glycopeptide can be effectively used for preventing and treating senile ossification, has the prospect of being developed into the medicine for preventing and treating senile ossification, provides more treatment choices for clinically preventing or treating senile ossification, and has important social benefits and economic values.
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