Compound feed additive for improving production performance of beef cattle and application

Abstract

The invention discloses a compound feed additive for improving the production performance of beef cattle and application, and belongs to the field of livestock feed. The compound feed additive provided by the invention comprises 35-45 parts of soybean meal extract, 20-30 parts of active dry yeast and 15-25 parts of cysteamine hydrochloride. The compound feed additive is added into cattle total mixed ration according to the mass ratio of 1: 1000 to feed beef cattle, and experimental results show that the compound feed additive disclosed by the invention can be used for promoting the intake of the beef cattle, improving the activity of rumen digestive enzyme, improving the digestion and absorption efficiency of nutrient substances and increasing the daily gain; in conclusion, the compound feed additive can significantly improve the production performance of beef cattle and improve the breeding benefits of the beef cattle. The invention provides a green, safe, efficient and low-cost compound feed additive for beef cattle feeding, and has important economic significance and wide application prospects.

Description

Technical Field

[0001] The present invention relates to the field of animal husbandry feed, in particular to a compound feed additive for improving the production performance of beef cattle and an application thereof. Background Art

[0002] Beef cattle farming is a vital component of animal husbandry. With the growing demand for meat, improving beef cattle production efficiency has become a key focus within the industry. In beef cattle farming, applying appropriate feed additives and scientifically optimizing feed during the fattening phase are key to improving production performance, enhancing farming profitability, and ensuring beef quality. With the advancement of beef cattle farming technology and the continuous innovation of feed additives, the screening and application of feed additives during the fattening phase have gained significant theoretical and practical significance.

[0003] Currently reported beef cattle feed additives are mainly composed of single nutrients, Chinese herbal extracts, or compound Chinese herbal extracts. These additives suffer from issues such as insignificant performance improvement, complex preparation methods, and high costs. Therefore, there is an urgent need to provide a feed additive that is simple to prepare, low-cost, safe, and efficient for improving beef cattle production performance. Summary of the Invention

[0004] The present invention aims to provide a compound feed additive and its application for improving the production performance of beef cattle, thereby overcoming the problems of the prior art. The compound feed additive of the present invention can significantly improve the production performance of beef cattle and enhance the breeding efficiency of beef cattle. The present invention provides a green, safe, efficient, and low-cost compound feed additive for beef cattle breeding, which has important economic significance and broad application prospects.

[0005] To achieve the above object, the present invention provides the following solutions:

[0006] The invention provides a compound feed additive, which comprises the following components in parts by mass: 35-45 parts of soybean meal extract, 20-30 parts of active dry yeast and 15-25 parts of cysteamine hydrochloride.

[0007] Furthermore, the following components are included, calculated by mass: 40 parts of soybean meal extract, 25 parts of active dry yeast and 20 parts of cysteamine hydrochloride.

[0008] Furthermore, the soybean meal extract includes the following components by mass: 0.93% soy isoflavones, 71.33% soy oligosaccharides, 7.20% soy saponins, 6.20% soy polypeptides and 14.34% carriers.

[0009] Furthermore, the soybean meal extract includes the following components by mass: 0.93% soy isoflavones, 42.60% sucrose, 22.60% stachyose and 6.13% raffinose, 7.20% soy saponin, 6.20% soy polypeptide and 14.34% carrier.

[0010] The present invention also provides an application of the compound feed additive in improving the production performance of beef cattle.

[0011] Furthermore, the production performance includes daily weight gain and dry matter intake.

[0012] The present invention also provides a use of the above-mentioned compound feed additive in preparing feed for improving the production performance of beef cattle and / or promoting digestion and absorption of beef cattle.

[0013] Furthermore, the production performance includes daily weight gain and dry matter intake;

[0014] The present invention also provides a feed for improving the production performance of beef cattle and / or promoting digestion and absorption of beef cattle, comprising a complete mixed ration for cattle and the above-mentioned compound feed additive.

[0015] Furthermore, the mass ratio of the compound feed additive to the complete mixed diet for cattle is 1:1000.

[0016] The present invention discloses the following technical effects:

[0017] The compound feed additive provided by the present invention includes 35-45 parts of soybean meal extract, 20-30 parts of active dry yeast and 15-25 parts of cysteamine hydrochloride. The compound feed additive is added to a complete mixed diet for cattle at a mass ratio of 1:1000 and fed to beef cattle. Experimental results show that the compound feed additive of the present invention can promote beef cattle to eat, increase the activity of rumen digestive enzymes, improve the digestion and absorption efficiency of nutrients, and increase daily weight gain; in short, the compound feed additive of the present invention can significantly improve the production performance of beef cattle and enhance the breeding efficiency of beef cattle. The present invention provides a green, safe, efficient and low-cost compound feed additive for beef cattle breeding, which has important economic significance and broad application prospects. DETAILED DESCRIPTION

[0018] Various exemplary embodiments of the present invention will now be described in detail. This detailed description should not be considered as limiting the present invention, but rather as a more detailed description of certain aspects, features, and embodiments of the present invention.

[0019] It should be understood that the terms described herein are intended only to describe particular embodiments and are not intended to limit the present invention. In addition, for numerical ranges herein, it should be understood that each intermediate value between the upper and lower limits of the range is also specifically disclosed. The intermediate value within any stated value or stated range, and each smaller range between any other stated value or intermediate value within the stated range, is also encompassed within the present invention. The upper and lower limits of these smaller ranges may be independently included or excluded within the scope.

[0020] Unless otherwise indicated, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art. Although only preferred methods and materials are described herein, any methods and materials similar or equivalent to those described herein may also be used in the practice or testing of the present invention. All documents mentioned in this specification are incorporated by reference to disclose and describe the methods and / or materials associated with the documents. In the event of any conflict with any incorporated document, the contents of this specification shall prevail.

[0021] It will be apparent to those skilled in the art that various modifications and variations may be made to the specific embodiments described herein without departing from the scope or spirit of the invention. Other embodiments will be apparent to those skilled in the art from the description of the invention. The description and examples are intended to be exemplary only.

[0022] The words “include,” “including,” “have,” “contain,” etc. used in this document are open-ended terms, meaning including but not limited to.

[0023] Soybean meal extract has many physiological functions: anti-lipid oxidation, antibacterial and antiviral detoxification, phytoestrogen function, promotion of cholesterol and fat metabolism, enhanced immune regulation function, anti-hemolysis function, prevention of liver damage, promotion of beneficial bacteria proliferation, regulation of intestinal flora balance, influence on digestive enzyme activity, water-soluble dietary fiber function, promotion of nutrient synthesis and utilization, etc.

[0024] Active dry yeast has the following biological effects and benefits: 1. Promotes digestion and absorption: The cell wall of active dry yeast is composed of glucans, glycoproteins, mannans, and chitin. The organic matter in the cell wall can serve as a nutritional supplement for cattle feed, improving feed utilization. Active dry yeast stimulates rumen microorganisms to secrete proteases and cellulases, while also synthesizing certain B vitamins, promoting digestion and absorption of nutrients. 2. Regulates immune activity: Influenced by the intestinal environment, dry yeast undergoes autolysis, releasing β-glucans and mannans in the cell wall and intracellular active substances. This modulates host immune gene expression and immune cell signaling, exerting immune functions by binding to polysaccharide receptors. 3. Prevents rumen acidosis: Active dry yeast stimulates the growth and reproduction of specific rumen bacterial communities, optimizes fermentation coupling, reduces the amount of carbon in the fermented product, and prevents rumen acidosis. Yeast promotes the growth and reproduction of cellulolytic and lactic acid-utilizing bacteria in the rumen, reducing lactic acid production, stabilizing rumen pH, and preventing acidosis. ④ Regulates intestinal flora: The β-glucans and mannooligosaccharides contained in active dry yeast help promote the growth and reproduction of beneficial rumen microorganisms. Yeast consumes oxygen in the rumen, creating an anaerobic environment that inhibits the colonization of harmful bacteria such as Escherichia coli, Salmonella, and Streptococcus, while providing a favorable growth environment for beneficial bacteria such as Bifidobacterium and Lactobacillus.

[0025] Cysteamine (CS) is an important bioactive substance and non-hormonal physiological regulator. The specific role of cysteamine in animal husbandry production: ① Promote animal growth: Cysteamine can increase the growth rate and weight gain of animals. It promotes the digestion and absorption of feed by increasing protein synthesis and utilization, thereby accelerating the growth and development of animals. ② Improve feed utilization: Cysteamine can promote the degradation and utilization of protein and improve the nitrogen utilization rate of feed. It can also increase the surface area of the small intestine and the activity of enzymes, thereby improving the digestibility and energy utilization of feed, so that the nutrients in the feed are more effectively utilized. ③ Improve the quality of dairy products: In dairy-producing animals such as dairy cows, cysteamine can increase milk production and improve the content of milk fat and protein, thereby improving the overall quality of dairy products. ④ Enhance immunity: Cysteamine can improve the immunity of animals and reduce the risk of disease. It enhances the resistance of animals by promoting the synthesis of antibodies and the activity of cellular immunity, helping to maintain the health of animals. ⑤ Metabolic Regulation: Cysteamine can regulate the metabolism of sugars, proteins, and fats, thereby promoting animal growth and improving production performance and carcass quality. It achieves this by depleting somatostatin in the animal's body and regulating the levels of growth hormone and growth-related hormones. ⑥ Specific Somatostatin Inhibition: Cysteamine can specifically bind to somatostatin, reducing or even eliminating its activity and increasing the synthesis and secretion of growth hormone. This mechanism of action makes cysteamine an effective growth promoter, capable of promoting animal growth without relying on traditional antibiotics.

[0026] The composition and nutritional ingredients of the total mixed ration (TMR) for beef cattle of the present invention are shown in Table 1.

[0027] Table 1 TMR composition and nutritional ingredients (air-dried basis)

[0028]

[0029]

[0030] The soybean meal extract of the present invention consists of the following components by mass: 0.93% soybean isoflavones, 71.33% soybean oligosaccharides (including 42.60% sucrose, 22.60% stachyose and 6.13% raffinose), 7.20% soybean saponin, 6.20% soybean polypeptide and 14.34% corn flour (carrier).

[0031] The active dry yeast of the present invention was purchased from Hubei Angel Yeast Co., Ltd., and the viable bacteria count in the active dry yeast was not less than 2×10 10 CFU / g.

[0032] The cysteamine hydrochloride (content 20%) of the present invention was purchased from Shandong Weifang Zhongtian Feed Science and Technology Co., Ltd.

[0033] Example 1

[0034] 800 g of soybean meal extract, 500 g of active dry yeast and 400 g of cysteamine hydrochloride are fully mixed to obtain a compound feed additive for improving the production performance of beef cattle.

[0035] Example 2

[0036] 900 g of soybean meal extract, 460 g of active dry yeast and 300 g of cysteamine hydrochloride are fully mixed to obtain a compound feed additive for improving the production performance of beef cattle.

[0037] Example 3

[0038] 840 g of soybean meal extract, 400 g of active dry yeast and 500 g of cysteamine hydrochloride are fully mixed to obtain a compound feed additive for improving the production performance of beef cattle.

[0039] Example 4

[0040] 700 g of soybean meal extract, 600 g of active dry yeast and 360 g of cysteamine hydrochloride are fully mixed to obtain a compound feed additive for improving the production performance of beef cattle.

[0041] Effect Verification Example 1

[0042] The compound feed additive prepared in Example 1 was subjected to effect verification to determine the effect of the compound feed additive on the production performance and digestion and absorption-related indicators of beef cattle (fattening cattle).

[0043] 1. Experimental Design

[0044] Twenty Simmental bulls of the same sex (male) and similar weight (500 ± 25 kg) were randomly divided into two groups based on weight: an experimental group and a control group, with 10 bulls in each group. The site was disinfected and the bulls were dewormed before the experiment. During the experiment, the bulls were fed a total mixed ration (TMR) once in the morning and evening, with free access to water.

[0045] During the 7-day pre-feeding period, the experimental group was given compound feed additives (the addition amount was 1 kg of compound feed additives per 1000 kg of complete mixed diet), while the control group did not use additives.

[0046] The main trial period lasted 55 days, with the same feeding regimen and additive dosage as during the pre-feeding period. Daily feed intake was accurately recorded, and fasting weights were performed at the beginning and end of the trial. Feces were collected for seven consecutive days during the main trial period to determine nutrient digestibility. Rumen fluid was extracted mid-trial to determine enzyme activity. Venous blood was collected on an fasting basis on the morning of the final day of the trial for measurement of glucose and lipid metabolism indicators.

[0047] 2. Test results and analysis

[0048] 2.1 Effects of compound feed additives on the production performance of fattening cattle

[0049] As can be seen from Table 2, there was no significant difference in the initial body weight between the two groups, which was in line with the completely randomized experimental design; the dry matter intake of the experimental group was 2.74% higher than that of the control group (P < 0.05), the average daily weight gain was 28.95% higher than that of the control group (P < 0.05), and the feed-to-weight ratio of the experimental group was reduced by 23.27% (P = 0.06). Although it did not reach a significant level, there was already a significant trend.

[0050] Table 2 Effects of compound feed additives on production performance of fattening cattle

[0051]

[0052] Note: No letters in the same row or the same letters in the same data indicate no significant difference (P>0.05), different lowercase letters indicate significant difference (P<0.05), and different uppercase letters indicate extremely significant difference (P<0.01).

[0053] 2.2 Effects of compound feed additives on the apparent digestibility of nutrients in fattening cattle

[0054] As shown in Table 3, the digestibility of dry matter in the experimental group was not significantly improved, but the digestibility of crude protein in the experimental group was 1.56% higher than that in the control group (P < 0.05), and the digestibility of neutral detergent fiber was 1.93% higher than that in the control group (P < 0.05).

[0055] Table 3 Effects of compound feed additives on the apparent digestibility of nutrients in fattening cattle (%)

[0056]

[0057] 2.3 Effects of compound feed additives on rumen digestive enzymes in fattening cattle

[0058] As can be seen from Table 4, the protease activity in the rumen fluid of the experimental group was increased by 8.87% (P < 0.01) and the amylase activity was increased by 10.27% (P < 0.05) compared with the control group. The pectinase activity in the rumen fluid of the experimental group was increased by 18.63% (P < 0.01) compared with the control group. However, the lipase, xylanase and filter paper enzyme activities in the rumen fluid of the experimental group were not significantly different from those of the control group (P > 0.05).

[0059] Table 4 Effects of compound feed additives on rumen digestive enzyme activities of fattening cattle

[0060]

[0061]

[0062] 2.4 Effects of compound feed additives on serum glucose and lipid metabolism indices in fattening cattle

[0063] As can be seen from Table 5, there was no significant difference in the urea nitrogen content in the serum between the experimental group and the control group (P>0.05), but the glucose content in the serum of the experimental group was 11.67% higher than that of the control group (P<0.01), and the cholesterol and triglyceride contents were 22.91% and 12.84% higher, respectively (P<0.01).

[0064] Table 5 Effects of compound feed additives on serum glucose and lipid metabolism indices in fattening cattle

[0065]

[0066] 3. Experimental conclusion

[0067] Based on the above experimental results, the compound feed additive in this effect verification example has a significant effect on promoting dry matter intake and weight gain of Simmental bulls, improving feed-to-weight ratio to a certain extent. It can also increase the activity of some rumen digestive enzymes and improve the digestion and absorption of nutrients.

[0068] The embodiments described above are merely descriptions of preferred embodiments of the present invention and are not intended to limit the scope of the present invention. Without departing from the spirit of the present invention, various modifications and improvements made to the technical solutions of the present invention by persons skilled in the art should fall within the scope of protection defined by the claims of the present invention.

Claims

1. A compound feed additive, characterized in that: The invention comprises the following components in parts by mass: 35-45 parts of soybean meal extract, 20-30 parts of active dry yeast and 15-25 parts of cysteamine hydrochloride.

2. The compound feed additive according to claim 1, wherein The preparation comprises the following components in parts by mass: 40 parts of soybean meal extract, 25 parts of active dry yeast and 20 parts of cysteamine hydrochloride.

3. The compound feed additive according to claim 1 or 2, wherein Calculated by mass, the soybean meal extract includes the following components: 0.93% soybean isoflavones, 71.33% soybean oligosaccharides, 7.20% soybean saponins, 6.20% soybean polypeptides and 14.34% carriers.

4. The compound feed additive according to claim 3, wherein The soybean meal extract comprises the following components by mass: 0.93% soybean isoflavones, 42.60% sucrose, 22.60% stachyose, 6.13% raffinose, 7.20% soybean saponin, 6.20% soybean polypeptide and 14.34% carrier.

5. Use of the compound feed additive according to any one of claims 1 to 4 in improving the production performance of beef cattle.

6. The use according to claim 5, characterized in that The production performance includes daily gain and dry matter intake.

7. Use of the compound feed additive according to any one of claims 1 to 4 in preparing feed for improving the production performance of beef cattle and / or promoting digestion and absorption of beef cattle.

8. The use according to claim 7, characterized in that The production performance includes daily gain and dry matter intake.

9. A feed for improving the production performance of beef cattle and / or promoting digestion and absorption of beef cattle, characterized in that: The invention comprises a complete mixed diet for cattle and the compound feed additive according to any one of claims 1 to 4.

10. The feed according to claim 9, wherein The mass ratio of the compound feed additive to the complete mixed diet for cattle is 1:1000.

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