Anti-hair-loss and oil-control composition, preparation method and application of anti-hair-loss and oil-control composition in hair washing products

Abstract

The invention provides an anti-hair-loss and oil-control composition, a preparation method and application of the anti-hair-loss and oil-control composition in hair washing products, and belongs to the technical field of cosmetics. The anti-hair loss and oil control composition is prepared from the following components: a cacumen biotae extract, sophorolipid, disodium azelate, a humectant and water, the mass ratio of the cacumen biotae extract to the sophorolipid to the disodium azelate is (0.8-1.2): (1.0-1.5): (1.0-1.5). The invention further provides application of the anti-hair-loss and oil-control composition in preparation of anti-hair-loss and oil-control shampoo, the anti-hair-loss and oil-control composition has better oil-control and antibacterial effects by controlling the specific components and proportion of the components, and the oil-control, itching-relieving and anti-hair-loss effects of the shampoo can be effectively improved by applying the anti-hair-loss and oil-control composition to the shampoo.

Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetics, and in particular relates to an anti-hair loss and oil control composition, a preparation method and application thereof in shampoo products. Background Art

[0002] In recent years, with the continuous upgrading of hair care concepts and the continued popularization of skin-care hair care concepts, more and more consumers believe that the scalp also needs to be taken seriously, and consumers' attitude towards scalp care has undergone a fundamental change from attention to action.

[0003] The scalp care market offers a wide range of benefits, but the overarching trend is a gradual evolution from basic deep cleansing and smoothing to oil control, volume enhancement, hair loss prevention, and hair growth. Due to the accelerated pace of life and increased work and lifestyle pressures, hair loss is a widespread problem, affecting younger people. Hair loss anxiety has become widespread, and hair loss prevention and growth have become both a pain point and a key focus for modern consumers in scalp care.

[0004] With the deepening of research, reports on the use of traditional Chinese medicine and other plant extracts in the treatment of hair loss are increasing. These plant-derived ingredients are relatively safe, effective, and easy to use. Animal studies have shown that astragalus, Polygonum multiflorum, Ligustrum lucidum, and Cuscuta chinensis, used alone or in combination, can stimulate the growth of hair follicles in cultured mice, increase follicle number, and accelerate hair regeneration. Clinical studies have also found that anti-hair loss and hair growth solutions composed of Chinese herbs such as Platycladus orientalis, Polygonum multiflorum, Ligustrum lucidum, Ligustrum lucidum, and Cuscuta chinensis can significantly promote hair growth in patients with hair loss. Therefore, this article summarizes recent research findings on the role of plant extracts in hair growth and development, and outlines the mechanisms by which plant extracts regulate hair follicle cell signaling pathways, in order to provide a theoretical basis for the mechanisms of action of plant extracts in hair growth and development and the development of clinical hair loss treatment agents.

[0005] Dihydrotestosterone (DHT), a metabolite of testosterone, plays a key role in androgenic alopecia. Patients with androgenic alopecia have higher levels of DHT in the scalp and serum, as well as higher levels and activity of 5α-reductase, than those in healthy individuals. This increases the ability of hair follicles to convert testosterone to DHT. Because 5α-reductase in hair follicles mediates the conversion of testosterone to DHT, the use of 5α-reductase inhibitors such as finasteride can prolong the growth phase of hair follicles, prevent hair loss, and promote hair growth. Experiments in mice have shown that extracts from Panax ginseng (CA Meyer) and alcohol extracts from Ligustrum lucidum (Ait.) can also inhibit 5α-reductase activity, reduce DHT levels in skin tissue, and promote hair growth. In addition, plant extracts such as fig (Ficus carica Linn.), rosemary (Rosmarinus officinalis), Ganoderma lucidum (Ganoderma lucidum), Polygonum multiflori (Polygonum multiflori), Cacumen platycladi and Cynomorium songaricum also have inhibitory effects on 5α-reductase, and therefore have great development prospects in preventing hair loss and promoting hair growth.

[0006] There are two main directions for hair loss prevention: (1) inhibiting the activity of 5α-reductase, reducing the level of dihydrotestosterone, and reducing oil secretion; (2) removing oil from the scalp to avoid clogging hair follicles and causing oil accumulation; therefore, there are many anti-hair loss and oil control products on the market.

[0007] Chinese patent CN119564575A discloses an anti-hair loss, oil-control, and anti-dandruff composition and its preparation method. The composition comprises 2-5 parts of mugwort leaf extract, 1.1-1.6 parts of ginger root extract, 5-10 parts of Polygonum multiflorum extract, and 4-6 parts of Platycladus orientalis leaf extract. The Polygonum multiflorum extract prepared by this inventive method exhibits good antibacterial activity, and mixed-strain fermentation is more effective in enriching the active ingredients in Polygonum multiflorum than fermentation with a single strain. While the anti-hair loss, oil-control, and anti-dandruff composition provided by this invention has both oil-control and oil-inhibiting effects, it is not very effective in removing scalp oil and regulating the scalp microbiome.

[0008] Chinese patent CN118986835A discloses an anti-hair loss and oil control composition, a preparation method and a use thereof. The anti-hair loss and oil control composition comprises, by weight, 1-20 parts of Platycladus orientalis leaf extract, 0.1-6 parts of tripeptide 1, 0.1-3 parts of myristoyl pentapeptide-4, 1-10 parts of loquat leaf extract, and 1-20 parts of bifid yeast fermentation product filtrate. The present invention adopts a compound of Platycladus orientalis leaf extract, tripeptide-1, myristoyl pentapeptide-4, loquat leaf extract, and bifid yeast fermentation product filtrate to produce a synergistic inhibition of 5α-reductase activity, significantly improving the inhibitory effect of 5α-reductase. However, this invention also has the problem of poor effect in removing scalp oil and regulating scalp microecology. The existing document "Analysis and Development of Anti-Hair Loss Shampoo Formula Ingredients, Perfect (Guangdong) Daily Necessities Co., Ltd., Lin Xiaofeng, Zhongshan, Guangdong, 528400" discloses that raw Platycladus orientalis leaves, Polygonum multiflorum, raw sun-dried ginseng, soapberry, ginger, Eclipta prostrata, Herba Polygonati Scutellariae, and Ligustrum lucidum fruits all have the effect of being used for hair care in traditional Chinese medicine. Raw Platycladus orientalis leaves are often used to treat problems such as dandruff and itchy scalp. Polygonum multiflorum has the effect of nourishing the liver and kidneys and blackening hair, and can enhance the elasticity and glossiness of hair. Raw sun-dried ginseng can moisturize hair, increase the softness and glossiness of hair, and help improve the problem of dry hair. Soapberry can effectively remove grease and dirt from hair, and also has anti-inflammatory and antipruritic effects. Ginger can promote blood circulation in the scalp, enhance the nutritional supply of hair, and help prevent hair loss and dry hair. Eclipta prostrata has the effect of nourishing hair and repairing hair scales, and is often used to treat problems such as dry and frizzy hair. Herba Ligustri Lucidi (Lavender's Ligustrum lucidum) has heat-clearing and detoxifying properties, dispelling wind and relieving itching, and can improve dandruff and itchy scalp. Ligustrum lucidum (Ligustrum lucidum) nourishes the liver and kidneys, darkens hair, and increases elasticity and luster, helping to prevent dryness and hair loss. The addition of these ingredients can enhance the hair-care benefits of shampoo and improve product quality, making them suitable ingredients for shampoo formulations.

[0009] In addition, Chinese herbal plant extracts have the advantages of easy access, simple production process, and low price. They are also compatible with many cosmetic raw materials. These plant extracts all have antioxidant and / or anti-inflammatory and antibacterial effects. For example, extracts from rosemary, ganoderma lucidum, ginseng, privet fruit, cynomorium songaricum, fig, polygonum multiflorum, and arborvitae can promote hair growth by inhibiting 5α-reductase, and have become a leading source of drug research and development for anti-hair loss and hair growth preparations. Existing results have demonstrated that a variety of plant extracts or their active ingredients have significant anti-hair loss and hair growth efficacy with minimal side effects. At the same time, compound Chinese herbal anti-hair loss cosmetics such as hair nourishing essences, Chinese herbal hair growth solutions, anti-hair loss and hair growth solutions, and Chinese herbal hair growth solutions, which are made by combining extracts from various plants such as ginseng, angelica, and polygonum multiflorum, have also been recognized for their efficacy and have good development prospects.

[0010] For example, the prior patent CN118121523A discloses a hair growth and black hair efficacy essence composition and its preparation method and application, wherein the essence composition comprises the following components by weight percentage: 2-5% plant extract; 0.2-0.8% moisturizer; 0.4-1.0% conditioner; 0.5-0.8% preservative; 0.2-0.4% antioxidant and the balance water; the application uses a mixture of rice bran extract, ginger root extract, ginseng root extract, kelp extract, grapefruit seed extract and Centella asiatica extract. The invention uses a plant extract as a plant extract, and controls the mass ratio of the plant extract, the moisturizing agent, and the conditioner to be 1-2:1-2:1-2:1-2:0.5-0.9:0.2-0.5. By controlling the specific components and mass ratios of the plant extract, the moisturizing agent, and the conditioner, the essence composition has better moisturizing, hair growth, and hair darkening effects. In terms of moisturizing, it can lock in moisture and achieve deeper moisturizing; in terms of hair growth, it can moisturize and repair hair follicles and stimulate hair follicle growth; in terms of hair darkening, it can effectively activate tyrosinase activity and promote melanin production. However, the patent also does not mention oil control and antibacterial effects.

[0011] For example, Chinese patent CN118662418A discloses a natural plant extract composition for preventing and strengthening hair loss. Through the synergistic effect of seven plant extracts reasonably proportioned, including Hypericum perforatum extract, Guaiacaceae extract, Mangostana mangostana peel extract, mango leaf extract, Polygonum multiflorum extract, Platycladus orientalis leaf extract, and ginger extract, the composition has a high inhibitory effect on 5α-reductase and major microorganisms such as Malassezia furfur, Propionibacterium acnes, and Staphylococcus aureus, which cause seborrheic alopecia. This reduces the probability of seborrheic alopecia. The beneficial ingredients in the seven plant extracts have the effects of promoting blood circulation and regulating scalp oil secretion, which can promote hair growth and improve the scalp environment. In addition, mango leaf extract and Polygonum multiflorum extract are rich in vitamins and nutrients, which can nourish hair, enhance hair elasticity and luster, and reduce hair breakage and shedding. However, the long-term antibacterial rate of the composition cannot better meet the demand.

[0012] Although the existing technology discloses that a variety of plant extracts have the effects of preventing hair loss, relieving itching, nourishing, and anti-inflammatory, some studies lack quality control, lack statutory toxicological safety evaluation, and lack accurate evaluation of the components of plant extracts, and there is no research on related hair solidification effects.

[0013] Therefore, it is necessary to develop an anti-hair loss and oil control composition and a preparation method thereof that can inhibit 5α-reductase activity, remove scalp oil, regulate scalp microecology, and have long-term antibacterial effects. Summary of the Invention

[0014] Based on the deficiencies in the prior art, the present invention aims to provide an anti-hair loss and oil control composition that can inhibit 5α-reductase activity, remove scalp oil, and regulate the scalp microecology, and a preparation method thereof. The use of this composition in shampoo products can significantly improve the anti-hair loss and oil control effects of the products.

[0015] In order to achieve the above object, the present invention adopts the following technical solutions:

[0016] An anti-hair loss and oil control composition comprises the following components: Platycladus orientalis leaf extract, sophorolipids, disodium azelaic acid, a moisturizer and water.

[0017] The mass ratio of the Platycladus orientalis leaf extract, sophorolipid and disodium azelaate is 0.8-1.2:1.0-1.5:1.0-1.5;

[0018] Preferably, the mass ratio of the Platycladus orientalis leaf extract, sophorolipids and disodium azelaate is 0.9-1.1:1.1-1.4:1.1-1.4;

[0019] More preferably, the mass ratio of the Platycladus orientalis leaf extract, sophorolipids and disodium azelaate is 1.0-1.1:1.2-1.3:1.2-1.3;

[0020] Further preferably, the mass ratio of the Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid is 1:1.2:1.2.

[0021] The moisturizing agent is glycerin.

[0022] As some preferred embodiments, the anti-hair loss and oil control composition comprises the following components by weight percentage:

[0023] 8-12% of Platycladus orientalis leaf extract, 10-15% of sophorolipids, 10-15% of disodium azelaic acid, 20-40% of glycerol and the balance of water.

[0024] As a preferred embodiment, the anti-hair loss and oil control composition comprises the following components by weight percentage:

[0025] Platycladus orientalis leaf extract 9-11%, sophorolipids 11-14%, disodium azelaic acid 11-14%, glycerol 25-35% and water as the balance.

[0026] Preferably, the Platycladus orientalis leaf extract has a weight percentage of 8%, 8.5%, 9%, 9.5%, 10%, 10.5%, 11%, 11.5% or 12%.

[0027] Preferably, the sophorolipid content by weight is 10%, 10.5%, 11%, 11.5%, 12%, 12.5%, 13%, 13.5%, 14%, 14.5% or 15%.

[0028] Preferably, the disodium azelaic acid content by weight is 10%, 10.5%, 11%, 11.5%, 12%, 12.5%, 13%, 13.5%, 14%, 14.5% or 15%.

[0029] Preferably, the glycerol content is 20%, 20.5%, 21%, 21.5%, 22%, 22.5%, 23%, 23.5%, 24%, 24.5% or 25% by weight.

[0030] As a most preferred embodiment, the anti-hair loss and oil control composition comprises the following components by weight percentage:

[0031] Platycladus orientalis leaf extract 10%, sophorolipids 12%, disodium azelaic acid 12%, glycerol 30% and water as the balance.

[0032] The Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid were all purchased from Guangzhou Huayue Medical Aesthetics Research Institute.

[0033] In another aspect, the present invention provides a method for preparing the above-mentioned anti-hair loss and oil control composition, comprising the following steps:

[0034] (1) mixing sugar and water and oil to obtain a mixture;

[0035] (2) Adding Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid to the mixture obtained in step (1) in sequence to obtain the anti-hair loss and oil control composition.

[0036] In another aspect, the present invention further provides the use of the above-mentioned anti-hair loss and oil control composition in the preparation of shampoo and hair care products.

[0037] An anti-hair loss and oil-control shampoo comprises the above-mentioned anti-hair loss and oil-control composition and auxiliary materials.

[0038] The auxiliary materials include one or more of a hair conditioner, a surfactant, a thickener, a preservative, a fragrance, an antidandruff agent, a pH adjuster and a colorant.

[0039] The hair conditioning agent includes one or more;

[0040] The hair conditioner includes hair conditioner 1, which is selected from one or more of ginger (Zingiber officinale) root extract, ginseng (Panax ginseng) root extract, kelp (Laminaria japonica) extract, grapefruit (CITRUS GRANDIS) seed extract, Centella asiatica (CENTELLA asiatica) extract and rice bran (ORYZASATIVA) extract;

[0041] Preferably, the hair conditioner 1 is a mixture of ginger (Zingiber officinale) root extract, ginseng (Panax ginseng) root extract, kelp (Laminaria japonica) extract, grapefruit (CITRUS GRANDIS) seed extract, Centella asiatica (CENTELLA ASIATICA) extract and rice bran (ORYZA SATIVA) extract;

[0042] Further preferably, the hair conditioner 1 is purchased from Guangzhou Huayue Medical Aesthetics Research Institute with the trade name HYFTGF003.

[0043] The hair conditioner further comprises a hair conditioner 2, which is an extract of aloe vera (ALOEBARBADENSIS) leaves.

[0044] Preferably, the Aloe Barbadensis leaf extract is purchased from Guangzhou Huayue Medical Aesthetics Research Institute with the trade name HYABW01.

[0045] The hair conditioner further comprises a hair conditioner 3, wherein the hair conditioner 3 is a ginseng root extract;

[0046] Preferably, the ginseng (PANAX GINSENG) root extract is purchased from Guangzhou Huayue Medical Aesthetics Research Institute.

[0047] The hair conditioner also includes hair conditioner 4, which is a flower extract of witch hazel (HAMAMELIS VIRGINIANA).

[0048] Preferably, the HAMAMELIS VIRGINIANA flower extract is purchased from Guangzhou Huayue Medical Aesthetics Research Institute with the trade name HYHVFW01.

[0049] The hair conditioner also includes a hair conditioner 5, which is polyquaternium-10.

[0050] Preferably, the polyquaternium-10 is purchased from Jingkun Oilfield Chemical Technology Co., Ltd., with the trade name SY-400 (version number A0).

[0051] The hair conditioner also includes hair conditioner 6, which is an extract of Ligusticum chuanxiong (LIGUSTICUM CHUANXIONG).

[0052] Preferably, the Ligusticum chuanxiong extract is purchased from Guangzhou Jianeng Biotechnology Co., Ltd.

[0053] The hair conditioner further comprises hair conditioner 7, which is di(PPG-2 myristeth-10) adipate.

[0054] Preferably, the di(PPG-2 myristeth-10) adipate is purchased from Guangzhou Huayue Medical Aesthetics Research Institute with the trade name HYSCE.

[0055] The surfactant includes one or more;

[0056] The surfactant includes surfactant 1, and the surfactant 1 is sodium lauryl polyether sulfate.

[0057] Preferably, the sodium laureth sulfate is purchased from BASF (China) Co., Ltd. with the trade name Texapon N 70 (AES).

[0058] The surfactant includes surfactant 2, and the surfactant 2 is sodium 2-methyl sulfolaurate.

[0059] Preferably, the sodium methyl 2-sulfolaurate is purchased from Guangzhou Palm Tree Chemical Co., Ltd. under the trade name MES.

[0060] The thickener includes one or more;

[0061] The thickener includes thickener 1, and the thickener 1 is sodium chloride.

[0062] Preferably, the sodium chloride is purchased from Jiangxi Jiuer Salt Industry Co., Ltd.

[0063] The thickener further comprises thickener 2, and the thickener 2 is cocamide MEA.

[0064] Preferably, the cocamide MEA is purchased from BASF (China) Co., Ltd. with the trade name Comperlan CMEA.

[0065] The preservative is phenoxyethanol and / or sodium benzoate.

[0066] Preferably, the preservative is purchased from Guangdong Dimei New Material Technology Co., Ltd.

[0067] The aromatic agent is a common fragrance for shampoo products.

[0068] Preferably, the fragrance is purchased from Guangzhou Fenhao Fragrance Co., Ltd. with the trade name FH20431449.

[0069] The anti-dandruff agent is piroctone olamine salt.

[0070] Preferably, the anti-dandruff agent is purchased from Shandong Oupali Biotechnology Co., Ltd. under the trade name OCT.

[0071] The pH regulator is citric acid.

[0072] Preferably, the citric acid is purchased from Weifang Yingxuan Industrial Co., Ltd.

[0073] The colorant is caramel color, purchased from Shandong Aipu Food Industry Co., Ltd.

[0074] The invention discloses an anti-hair loss and oil control shampoo, which comprises the following components by weight: 0.8-3% of an anti-hair loss and oil control composition, 5-15% of a hair conditioner, 15-25% of a surfactant, 1-5% of a thickener, 0.5-1.0% of a preservative, 0.1-0.6% of a fragrance, 0.1-0.5% of an antidandruff agent, 0.1-0.3% of a pH conditioner, 0.04-0.08% of a colorant, and the balance being water.

[0075] Preferably, the anti-hair loss and oil control shampoo comprises the following components by weight percentage: 1.0-2% of the anti-hair loss and oil control composition, 10-12% of the hair conditioner, 15-20% of the surfactant, 2-4% of the thickener, 0.6-0.9% of the preservative, 0.2-0.5% of the fragrance, 0.2-0.4% of the anti-dandruff agent, 0.2-0.3% of the pH conditioner, 0.05-0.07% of the colorant and the balance of water.

[0076] Preferably, the anti-hair loss and oil control composition has a content by weight of 0.8%, 0.9%, 1.0%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2.0%, 2.1%, 2.2%, 2.3%, 2.4%, 2.5%, 2.6%, 2.7%, 2.8%, 2.9% or 3.0%.

[0077] Preferably, the hair conditioner is present in an amount of 5%, 5.5%, 6.0%, 6.5%, 7.0%, 7.5%, 8.0%, 8.5%, 9.0%, 9.5%, 10%, 10.5%, 11.0%, 11.5%, 12.0%, 12.5%, 13.0%, 13.5%, 14.0%, 14.5% or 15% by weight.

[0078] Preferably, the surfactant is present in an amount of 15%, 15.5%, 16%, 16.5%, 17%, 17.5%, 18%, 18.5%, 19%, 19.5%, 20.0%, 20.5%, 21%, 21.5%, 22%, 22.5%, 23%, 23.5%, 24%, 24.5% or 25% by weight.

[0079] Preferably, the thickener is present in an amount of 1%, 1.5%, 2.0%, 2.5%, 3.0%, 3.5%, 4.0%, 4.5% or 5.0% by weight.

[0080] Preferably, the preservative is present in an amount of 0.5%, 0.6%, 0.7%, 0.8%, 0.9% or 1.0% by weight.

[0081] Preferably, the fragrance has a weight percentage of 0.1%, 0.2%, 0.3%, 0.4%, 0.5% or 0.6%.

[0082] Preferably, the anti-dandruff agent has a weight percentage of 0.1%, 0.2%, 0.3%, 0.4% or 0.5%.

[0083] Preferably, the pH adjuster has a weight percentage of 0.1%, 0.2% or 0.3%.

[0084] Preferably, the colorant has a weight percentage of 0.04%, 0.05%, 0.06%, 0.07% or 0.08%.

[0085] As some preferred embodiments, the hair conditioner is a mixture of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7.

[0086] Preferably, the mass ratio of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7 is 2-5:1-3:1-3:1-3:0.1-0.5:0.1-0.5:0.1-0.3.

[0087] More preferably, the mass ratio of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7 is 3-4:2-3:2-3:2-3:0.2-0.4:0.2-0.4:0.1-0.2.

[0088] Further preferably, the mass ratio of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7 is 3:2.6:2.6:2.6:0.35:0.3:0.15.

[0089] As some preferred embodiments, the surfactant is a mixture of surfactant 1 and surfactant 2.

[0090] Preferably, the mass ratio of surfactant 1 to surfactant 2 is 6-10:1.

[0091] More preferably, the mass ratio of surfactant 1 to surfactant 2 is 7-9:1.

[0092] Further preferably, the mass ratio of surfactant 1 to surfactant 2 is 8:1.

[0093] As some preferred embodiments, the thickener is a mixture of thickener 1 and thickener 2.

[0094] Preferably, the mass ratio of thickener 1 to thickener 2 is 1-3:1.

[0095] More preferably, the mass ratio of thickener 1 to thickener 2 is 2-3:1.

[0096] Further preferably, the mass ratio of thickener 1 to thickener 2 is 2-2.5:1.

[0097] As a preferred embodiment, the anti-hair loss and oil control shampoo comprises the following components by weight percentage:

[0098] Anti-hair loss and oil control composition 1.1%, HYFTGF003 3%, HYABW01 2.6%, ginseng root (PANAX GINSENG) extract 2.6%, HYHVFW01 2.6%, SY-400 0.35%, Ligusticum chuanxiong (LIGUSTICUM CHUANXIONG) extract 0.3%, di (PPG-2 myristeth-10) adipate 0.15%, Texapon N 70 16%, MES2%, sodium chloride 2.5%, Comperlan CMEA 1.2%, phenoxyethanol 0.5%, sodium benzoate 0.4%, FH20431449 0.4%, OCT 0.3%, citric acid 0.2%, caramel color 0.06% and water as the balance.

[0099] The present invention also provides a method for preparing the above-mentioned anti-hair loss and oil-control shampoo, comprising the following steps:

[0100] (1) Place water (80% total water content), surfactant 1, and hair conditioner 7 into a stirring pot and heat to 80-85° C. while stirring until all the ingredients are dissolved to obtain mixture 1;

[0101] (2) Mix hair conditioner 6 and heat at 85°C until completely dissolved. Then add surfactant 2 and thickener 2 and heat and stir for 30 minutes until all the ingredients are dissolved to obtain mixture 2.

[0102] (3) Cooling the mixture 2 to below 45° C., adding hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, the anti-hair loss and oil control composition, and hair conditioner 7, and homogenizing and stirring to obtain a mixture 3;

[0103] (4) After the piroctone olamine salt and the remaining water are mixed and dispersed, the remaining raw materials are added in sequence and homogenized for 3 minutes at a homogenization speed of 45 rpm until no solid particles are present, to obtain a mixture 4;

[0104] (5) At 45°C, mixture 3 was added to mixture 1 and stirred evenly, and then mixture 4 was added and stirred until uniform. The mixture was cooled to room temperature to obtain the anti-hair loss and oil control shampoo.

[0105] Compared with the prior art, the present invention has the following beneficial effects:

[0106] (1) The present invention uses a variety of hair conditioners:

[0107] A mixture of ginger (Zingiber officinale) root extract, ginseng (PANAX GINSENG) root extract, kelp (LAMINARIA JAPONICA) extract, grapefruit (CITRUS GRANDIS) seed extract, centella asiatica (CENTELLA ASIATICA) extract and rice bran (ORYZA SATIVA) extract is used as hair conditioning agent 1.

[0108] in,

[0109] Ginger (Zingiber Officinale) Root Extract: This ingredient can inhibit the activity of Malassezia fungus, reduce scalp inflammation, and regulate sebaceous gland secretion, thereby improving the scalp environment. It has strong antioxidant properties, helping to protect hair from free radical damage, enhancing hair luster and improving its resistance to breakage. Its active ingredients can stimulate the scalp, promote blood circulation, and help improve the nutrient supply to hair follicles.

[0110] Ginseng (PANAX GINSENG) root extract: can increase the expansion of capillaries in the head, thereby providing more nutrition to the hair and enhancing its toughness; helps improve blood circulation in the scalp, promotes the health of hair follicles, and thus reduces hair loss and breakage; by promoting the health of hair follicles, ginseng root extract can enhance the health of hair roots and reduce hair problems caused by malnutrition or poor blood circulation.

[0111] Kelp (LAMINARIA JAPONICA) extract: has antioxidant and anti-aging effects; can inhibit the generation of oxygen free radicals, thereby slowing down the aging process of skin and hair, maintaining the health of scalp and hair, delaying scalp aging, and reducing fine lines and sagging.

[0112] Citrus Grandis seed extract: Rich in B vitamins, protein and other trace elements, it can provide sufficient nourishment for hair, prevent hair loss and promote healthy hair growth; its nutrients have anti-inflammatory and qi-regulating effects, can stimulate hair follicles and accelerate hair growth; it has a strong effect on eliminating free radicals and has anti-aging and antioxidant effects.

[0113] Centella asiatica extract: rich in antioxidants, can reduce hair damage, increase elasticity and prevent breakage; has a soothing and calming effect, can reduce hair loss, while soothing the scalp and building a strong scalp barrier; can promote cell vitality and help hair growth.

[0114] Rice (Oryza sativa) bran extract: This extract improves skin's softness by promoting the production of cholesterol and ceramides, increasing sebum levels. It also possesses antioxidant properties and can activate glutathione reductase, thus aiding in anti-aging efforts. These properties make rice (Oryza sativa) bran extract a promising addition to shampoo products, improving scalp and hair health and reducing hair loss and thinning.

[0115] The use of plant extracts can improve the scalp microenvironment, promote hair follicle health, and promote cell vitality, thereby achieving the purpose of strengthening hair and preventing hair loss.

[0116] Aloe barbadensis leaf extract is used as a hair conditioning agent 2. This ingredient has anti-inflammatory effects and can effectively reduce local inflammation levels on the skin, thereby achieving the purpose of soothing the skin.

[0117] Use HAMAMELIS VIRGINIANA flower extract as a hair conditioner. 4 This ingredient can control oil secretion, help regulate the skin's water and oil balance, effectively increase the skin's moisture content, balance the pH value, and shrink pores.

[0118] Ligusticum chuanxiong extract is used as hair conditioning agent 7. This ingredient has antibacterial and anti-inflammatory effects, can inhibit the excessive growth of scalp fungi, and has a relieving effect on increased dandruff and itching caused by seborrheic dermatitis or mild scalp inflammation.

[0119] The present invention uses a variety of plant extracts as hair conditioners, which can improve the scalp microenvironment, promote hair follicle health, promote cell vitality, and achieve the purpose of oil control, antibacterial, and anti-hair loss.

[0120] (2) The present invention also provides an anti-hair loss and oil control composition, wherein the flavonoids in the Platycladus orientalis leaf extract can effectively control the secretion of 5a-reductase, thereby controlling the secretion of scalp oil; sophorolipids are plant glycolipids of natural origin, which can deeply clean the scalp with extremely low surface tension; disodium azelaic acid can stabilize the sebaceous glands, thereby reducing oil secretion. The present invention mixes and compounds the Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid, and by controlling their mass ratio, the obtained anti-hair loss and oil control composition has a better oil control effect, thereby improving the scalp microenvironment and reducing hair loss. DETAILED DESCRIPTION

[0121] The following will be combined with the tables in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0122] Hereinafter, examples of the present invention and comparative examples will be shown to explain the composition of the present invention in more detail, but the present invention is not limited thereto.

[0123] The present invention does not limit the sources of the raw materials used. Unless otherwise specified, the raw materials used in the present invention are common commercial products in the technical field.

[0124] In one aspect, the present invention provides an anti-hair loss and oil control composition comprising the following components: Platycladus orientalis leaf extract, sophorolipids, disodium azelaic acid, a moisturizer, and water.

[0125] The mass ratio of the Platycladus orientalis leaf extract, sophorolipid and disodium azelaate is 0.8-1.2:1.0-1.5:1.0-1.5;

[0126] Preferably, the mass ratio of the Platycladus orientalis leaf extract, sophorolipids and disodium azelaate is 0.9-1.1:1.1-1.4:1.1-1.4;

[0127] More preferably, the mass ratio of the Platycladus orientalis leaf extract, sophorolipids and disodium azelaate is 1.0-1.1:1.2-1.3:1.2-1.3;

[0128] Further preferably, the mass ratio of the Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid is 1:1.2:1.2.

[0129] The moisturizing agent is glycerin.

[0130] As some preferred embodiments, the anti-hair loss and oil control composition comprises the following components by weight percentage:

[0131] 8-12% of Platycladus orientalis leaf extract, 10-15% of sophorolipids, 10-15% of disodium azelaic acid, 20-40% of glycerol and the balance of water.

[0132] As a preferred embodiment, the anti-hair loss and oil control composition comprises the following components by weight percentage:

[0133] Platycladus orientalis leaf extract 9-11%, sophorolipids 11-14%, disodium azelaic acid 11-14%, glycerol 25-35% and water as the balance.

[0134] Preferably, the Platycladus orientalis leaf extract has a weight percentage of 8%, 8.5%, 9%, 9.5%, 10%, 10.5%, 11%, 11.5% or 12%.

[0135] Preferably, the sophorolipid content by weight is 10%, 10.5%, 11%, 11.5%, 12%, 12.5%, 13%, 13.5%, 14%, 14.5% or 15%.

[0136] Preferably, the disodium azelaic acid content by weight is 10%, 10.5%, 11%, 11.5%, 12%, 12.5%, 13%, 13.5%, 14%, 14.5% or 15%.

[0137] Preferably, the glycerol content is 20%, 20.5%, 21%, 21.5%, 22%, 22.5%, 23%, 23.5%, 24%, 24.5% or 25% by weight.

[0138] As a most preferred embodiment, the anti-hair loss and oil control composition comprises the following components by weight percentage:

[0139] Platycladus orientalis leaf extract 10%, sophorolipids 12%, disodium azelaic acid 12%, glycerol 30% and water as the balance.

[0140] In another aspect, the present invention provides a method for preparing the above-mentioned anti-hair loss and oil control composition, comprising the following steps:

[0141] (1) mixing glycerol and water to obtain a mixture;

[0142] (2) Adding Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid to the mixture obtained in step (1) in sequence to obtain the anti-hair loss and oil control composition.

[0143] In another aspect, the present invention further provides an anti-hair loss and oil-control shampoo, comprising the above-mentioned anti-hair loss and oil-control composition and auxiliary materials.

[0144] The auxiliary materials include one or more of a hair conditioner, a surfactant, a thickener, a preservative, a fragrance, an antidandruff agent, a pH adjuster and a colorant.

[0145] The hair conditioning agent includes one or more;

[0146] The hair conditioner includes hair conditioner 1, which is selected from one or more of ginger (Zingiber officinale) root extract, ginseng (Panax ginseng) root extract, kelp (Laminaria japonica) extract, grapefruit (CITRUS GRANDIS) seed extract, Centella asiatica (CENTELLA asiatica) extract and rice bran (ORYZASATIVA) extract;

[0147] Preferably, the hair conditioner 1 is a mixture of ginger (Zingiber officinale) root extract, ginseng (Panax ginseng) root extract, kelp (Laminaria japonica) extract, grapefruit (CITRUS GRANDIS) seed extract, Centella asiatica (CENTELLA asiatica) extract and rice bran (ORYZASATIVA) extract;

[0148] Further preferably, the hair conditioner 1 is purchased from Guangzhou Huayue Medical Aesthetics Research Institute with the trade name HYFTGF003.

[0149] The hair conditioner further comprises a hair conditioner 2, which is an extract of aloe vera (ALOEBARBADENSIS) leaves.

[0150] Preferably, the Aloe Barbadensis leaf extract is purchased from Guangzhou Huayue Medical Aesthetics Research Institute with the trade name HYABW01.

[0151] The hair conditioner further comprises a hair conditioner 3, wherein the hair conditioner 3 is a ginseng root extract;

[0152] Preferably, the ginseng (PANAX GINSENG) root extract is purchased from Guangzhou Huayue Medical Aesthetics Research Institute.

[0153] The hair conditioner also includes hair conditioner 4, which is a flower extract of witch hazel (HAMAMELIS VIRGINIANA).

[0154] Preferably, the HAMAMELIS VIRGINIANA flower extract is purchased from Guangzhou Huayue Medical Aesthetics Research Institute with the trade name HYHVFW01.

[0155] The hair conditioner also includes a hair conditioner 5, which is polyquaternium-10.

[0156] Preferably, the polyquaternium-10 is purchased from Jingkun Oilfield Chemical Technology Co., Ltd., with the trade name SY-400 (version number A0).

[0157] The hair conditioner also includes hair conditioner 6, which is an extract of Ligusticum chuanxiong (LIGUSTICUM CHUANXIONG).

[0158] Preferably, the Ligusticum chuanxiong extract is purchased from Guangzhou Jianeng Biotechnology Co., Ltd.

[0159] The hair conditioner further comprises hair conditioner 7, which is di(PPG-2 myristeth-10) adipate.

[0160] Preferably, the di(PPG-2 myristeth-10) adipate is purchased from Guangzhou Huayue Medical Aesthetics Research Institute with the trade name HYSCE.

[0161] The surfactant includes one or more;

[0162] The surfactant includes surfactant 1, and the surfactant 1 is sodium lauryl polyether sulfate.

[0163] Preferably, the sodium laureth sulfate is purchased from BASF (China) Co., Ltd., with the trade name Texapon N 70 (AES).

[0164] The surfactant includes surfactant 2, and the surfactant 2 is sodium 2-methyl sulfolaurate.

[0165] Preferably, the sodium methyl 2-sulfolaurate is purchased from Guangzhou Palm Tree Chemical Co., Ltd. under the trade name MES.

[0166] The thickener includes one or more;

[0167] The thickener includes thickener 1, and the thickener 1 is sodium chloride.

[0168] Preferably, the sodium chloride is purchased from Jiangxi Jiuer Salt Industry Co., Ltd.

[0169] The thickener further comprises thickener 2, and the thickener 2 is cocamide MEA.

[0170] Preferably, the cocamide MEA is purchased from BASF (China) Co., Ltd. with the trade name Comperlan CMEA.

[0171] The preservative is phenoxyethanol and / or sodium benzoate.

[0172] Preferably, the preservative is purchased from Guangdong Dimei New Material Technology Co., Ltd.

[0173] The aromatic agent is a common fragrance for shampoo products.

[0174] Preferably, the fragrance is purchased from Guangzhou Fenhao Fragrance Co., Ltd. with the trade name FH20431449.

[0175] The anti-dandruff agent is piroctone olamine salt.

[0176] Preferably, the anti-dandruff agent is purchased from Shandong Oupali Biotechnology Co., Ltd. under the trade name OCT.

[0177] The pH regulator is citric acid.

[0178] Preferably, the citric acid is purchased from Weifang Yingxuan Industrial Co., Ltd.

[0179] The colorant is caramel color, purchased from Shandong Aipu Food Industry Co., Ltd.

[0180] The invention discloses an anti-hair loss and oil control shampoo, which comprises the following components by weight: 0.8-3% of an anti-hair loss and oil control composition, 5-15% of a hair conditioner, 15-25% of a surfactant, 1-5% of a thickener, 0.5-1.0% of a preservative, 0.1-0.6% of a fragrance, 0.1-0.5% of an antidandruff agent, 0.1-0.3% of a pH conditioner, 0.04-0.08% of a colorant, and the balance being water.

[0181] Preferably, the anti-hair loss and oil control shampoo comprises the following components by weight percentage: 1.0-2% of the anti-hair loss and oil control composition, 10-12% of the hair conditioner, 15-20% of the surfactant, 2-4% of the thickener, 0.6-0.9% of the preservative, 0.2-0.5% of the fragrance, 0.2-0.4% of the anti-dandruff agent, 0.2-0.3% of the pH conditioner, 0.05-0.07% of the colorant and the balance of water.

[0182] Preferably, the anti-hair loss and oil control composition has a content by weight of 0.8%, 0.9%, 1.0%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2.0%, 2.1%, 2.2%, 2.3%, 2.4%, 2.5%, 2.6%, 2.7%, 2.8%, 2.9% or 3.0%.

[0183] Preferably, the hair conditioner is present in an amount of 5%, 5.5%, 6.0%, 6.5%, 7.0%, 7.5%, 8.0%, 8.5%, 9.0%, 9.5%, 10%, 10.5%, 11.0%, 11.5%, 12.0%, 12.5%, 13.0%, 13.5%, 14.0%, 14.5% or 15% by weight.

[0184] Preferably, the surfactant is present in an amount of 15%, 15.5%, 16%, 16.5%, 17%, 17.5%, 18%, 18.5%, 19%, 19.5%, 20.0%, 20.5%, 21%, 21.5%, 22%, 22.5%, 23%, 23.5%, 24%, 24.5% or 25% by weight.

[0185] Preferably, the thickener is present in an amount of 1%, 1.5%, 2.0%, 2.5%, 3.0%, 3.5%, 4.0%, 4.5% or 5.0% by weight.

[0186] Preferably, the preservative is present in an amount of 0.5%, 0.6%, 0.7%, 0.8%, 0.9% or 1.0% by weight.

[0187] Preferably, the fragrance has a weight percentage of 0.1%, 0.2%, 0.3%, 0.4%, 0.5% or 0.6%.

[0188] Preferably, the anti-dandruff agent has a weight percentage of 0.1%, 0.2%, 0.3%, 0.4% or 0.5%.

[0189] Preferably, the pH adjuster has a weight percentage of 0.1%, 0.2% or 0.3%.

[0190] Preferably, the colorant has a weight percentage of 0.04%, 0.05%, 0.06%, 0.07% or 0.08%.

[0191] As some preferred embodiments, the hair conditioner is a mixture of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7.

[0192] Preferably, the mass ratio of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7 is 2-5:1-3:1-3:1-3:0.1-0.5:0.1-0.5:0.1-0.3.

[0193] More preferably, the mass ratio of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7 is 3-4:2-3:2-3:2-3:0.2-0.4:0.2-0.4:0.1-0.2.

[0194] Further preferably, the mass ratio of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7 is 3:2.6:2.6:2.6:0.35:0.3:0.15.

[0195] As some preferred embodiments, the surfactant is a mixture of surfactant 1 and surfactant 2.

[0196] Preferably, the mass ratio of surfactant 1 to surfactant 2 is 6-10:1.

[0197] More preferably, the mass ratio of surfactant 1 to surfactant 2 is 7-9:1.

[0198] Further preferably, the mass ratio of surfactant 1 to surfactant 2 is 8:1.

[0199] As some preferred embodiments, the thickener is a mixture of thickener 1 and thickener 2.

[0200] Preferably, the mass ratio of thickener 1 to thickener 2 is 1-3:1.

[0201] More preferably, the mass ratio of thickener 1 to thickener 2 is 2-3:1.

[0202] Further preferably, the mass ratio of thickener 1 to thickener 2 is 2-2.5:1.

[0203] As a preferred embodiment, the anti-hair loss and oil control shampoo comprises the following components by weight percentage:

[0204] Anti-hair loss and oil control composition 1.1%, HYFTGF003 3%, HYABW01 2.6%, ginseng root (PANAX GINSENG) extract 2.6%, HYHVFW01 2.6%, SY-400 0.35%, Ligusticum chuanxiong (LIGUSTICUM CHUANXIONG) extract 0.3%, di (PPG-2 myristeth-10) adipate 0.15%, Texapon N 70 16%, MES 2%, sodium chloride 2.5%, Comperlan CMEA 1.2%, phenoxyethanol 0.5%, sodium benzoate 0.4%, FH20431449 0.4%, OCT 0.3%, citric acid 0.2%, caramel color 0.06% and water as the balance.

[0205] The present invention also provides a method for preparing the above-mentioned anti-hair loss and oil-control shampoo, comprising the following steps:

[0206] (1) Place water (80% total water content), surfactant 1, and hair conditioner 7 into a stirring pot and heat to 80-85° C. while stirring until all the ingredients are dissolved to obtain mixture 1;

[0207] (2) Mix hair conditioner 6 and heat at 85°C until completely dissolved. Then add surfactant 2 and thickener 2 and heat and stir for 30 minutes until all the ingredients are dissolved to obtain mixture 2.

[0208] (3) Cooling the mixture 2 to below 45° C., adding hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, the anti-hair loss and oil control composition, and hair conditioner 7, and homogenizing and stirring to obtain a mixture 3;

[0209] (4) After the piroctone olamine salt and the remaining water are mixed and dispersed, the remaining raw materials are added in sequence and homogenized for 3 minutes at a homogenization speed of 45 rpm until no solid particles are present, to obtain a mixture 4;

[0210] (5) At 45°C, mixture 3 was added to mixture 1 and stirred evenly, and then mixture 4 was added and stirred until uniform. The mixture was cooled to room temperature to obtain the anti-hair loss and oil control shampoo.

[0211] Example 1: An anti-hair loss and oil control composition and its preparation method

[0212] The components are calculated by weight percentage:

[0213] Components content Platycladus orientalis leaf extract 8％ Sophorolipids 10％ Disodium Azelaic Acid 10％ glycerin 20％ water margin

[0214] The preparation method is:

[0215] (1) mixing glycerol and water to obtain a mixture;

[0216] (2) Adding Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid to the mixture obtained in step (1) in sequence to obtain the anti-hair loss and oil control composition.

[0217] Example 2: An anti-hair loss and oil control composition and its preparation method

[0218] The components are calculated by weight percentage:

[0219] Components content Platycladus orientalis leaf extract 12％ Sophorolipids 15％ Disodium Azelaic Acid 15％ glycerin 40％ water margin

[0220] The preparation method is:

[0221] (1) mixing glycerol and water to obtain a mixture;

[0222] (2) Adding Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid to the mixture obtained in step (1) in sequence to obtain the anti-hair loss and oil control composition.

[0223] Example 3: An anti-hair loss and oil control composition and its preparation method

[0224] The components are calculated by weight percentage:

[0225] Components content Platycladus orientalis leaf extract 10％ Sophorolipids 12％ Disodium Azelaic Acid 14％ glycerin 25％ water margin

[0226] The preparation method is:

[0227] (1) mixing glycerol and water to obtain a mixture;

[0228] (2) Adding Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid to the mixture obtained in step (1) in sequence to obtain the anti-hair loss and oil control composition.

[0229] Example 4: An anti-hair loss and oil control composition and its preparation method

[0230] The components are calculated by weight percentage:

[0231] Components content Platycladus orientalis leaf extract 11％ Sophorolipids 15％ Disodium Azelaic Acid 10％ glycerin 30％ water margin

[0232] The preparation method is:

[0233] (1) mixing glycerol and water to obtain a mixture;

[0234] (2) Adding Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid to the mixture obtained in step (1) in sequence to obtain the anti-hair loss and oil control composition.

[0235] Example 5: An anti-hair loss and oil control composition and its preparation method

[0236] The components are calculated by weight percentage:

[0237]

[0238]

[0239] The preparation method is:

[0240] (1) mixing glycerol and water to obtain a mixture;

[0241] (2) Adding Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid to the mixture obtained in step (1) in sequence to obtain the anti-hair loss and oil control composition.

[0242] Comparative Example 1

[0243] The difference from Example 5 is that the sophorolipid is omitted, the content of disodium azelaic acid is increased to 20%, and the content of Platycladus orientalis leaf extract is increased to 15%. Other contents are the same as Example 5.

[0244] Right now:

[0245] Components content Platycladus orientalis leaf extract 15％ Sophorolipids - Disodium Azelaic Acid 20％ glycerin 30％ water margin

[0246] Comparative Example 2

[0247] The difference from Example 5 is that the Platycladus orientalis leaf extract is omitted, the content of sophorolipids is increased to 20%, and the content of disodium azelaic acid is increased to 15%. Other contents are the same as Example 5.

[0248] Right now:

[0249] Components content Platycladus orientalis leaf extract - Sophorolipids 20％ Disodium Azelaic Acid 15％ glycerin 30％ water margin

[0250] Comparative Example 3

[0251] The difference from Example 5 is that the mass ratio of Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid is changed to 0.4:1:2, that is, 4% Platycladus orientalis leaf extract, 10% sophorolipids, 20% disodium azelaic acid, 30% glycerol and the balance water, and the rest is the same as Example 5.

[0252] Right now:

[0253] Components content Platycladus orientalis leaf extract 4％ Sophorolipids 10％ Disodium Azelaic Acid 20％ glycerin 30％ water margin

[0254] Comparative Example 4

[0255] The difference from Example 5 is that the mass ratio of Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid is changed to 2:0.4:1, that is, 20% Platycladus orientalis leaf extract, 4% sophorolipids, 10% disodium azelaic acid, 30% glycerol and the balance water, and the rest is the same as Example 5.

[0256] Right now:

[0257] Components content Platycladus orientalis leaf extract 20％ Sophorolipids 4％ Disodium Azelaic Acid 10％ glycerin 30％ water margin

[0258] Effect detection:

[0259] 1. 5α-reductase inhibition assay

[0260] 1.1 Test purpose and principle:

[0261] Seborrhea is a disorder of sebaceous gland function, resulting in excessive sebum secretion. This leads to excess oil accumulation in the skin and hair, resulting in a greasy, shiny appearance and the appearance of scaling. Sex hormone imbalance, primarily elevated androgen levels, can lead to increased sebaceous gland secretion. Androgens, androgen receptors, and the activity of androgen-metabolizing enzymes can all affect oil secretion.

[0262] There are two types of the androgen-metabolizing enzyme 5α-reductase. Type I is found in the liver and sebaceous glands, while type II is primarily found in the hair follicles of the scalp and beard, along with gonadal tissue. 5α-reductase converts the androgen testosterone and the reducing coenzyme NADPH into dihydrotestosterone. Dihydrotestosterone's binding activity to androgen receptors is five times that of testosterone, promoting cellular processes and inducing increased sebum secretion in the sebaceous glands. 5α-reductase activity can influence oil secretion in different parts of the body.

[0263] Based on this principle, this experiment uses UV spectrophotometry to measure 5α-reductase activity, with changes in the concentration of the reducing coenzyme reflecting 5α-reductase activity. Finally, the degree of inhibition of 5α-reductase activity by the experimental sample is used to preliminarily determine the oil-control efficacy of the cosmetic product. A higher inhibition rate indicates a stronger oil-control effect, while a lower inhibition rate indicates a weaker effect.

[0264] 1.2 Judgment criteria:

[0265] The higher the 5α-reductase activity inhibition rate, the stronger the oil control effect of the substance.

[0266] 1.3 Test method:

[0267] (1) Sample processing;

[0268] (2) reacting the sample with a solution of 5α-reductase;

[0269] (3) Measure absorbance at 340 nm;

[0270] (4) Calculate the inhibition rate of 5α-reductase activity.

[0271] The sample preparation for this test is as follows: weigh 0.5 g of sample, add Tris buffer to 10 ml, shake to disperse, ultrasonicate for 10 min, centrifuge at 5000 rpm for 5 min, and take the supernatant for the experiment.

[0272] The negative control was a 5α-reductase reaction system, and the enzyme reaction system was incubated at 37°C for 30 minutes.

[0273] 1.4 Test results:

[0274] The absorbance measurement results at different times are shown in Table 1, and the 5α-reductase activity inhibition rate test results are shown in Table 2.

[0275] Table 1 Absorbance measurement results at different times

[0276] time A(0min) A(60min) ΔA Negative test absorbance A0 0.287 0.207 0.080 Example 1 Sample Experiment Absorbance A1 0.295 0.250 0.045 Example 2 Sample Experiment Absorbance A2 0.298 0.256 0.042 Example 3 Sample Experiment Absorbance A3 0.289 0.248 0.041 Example 4 Sample Experiment Absorbance A4 0.294 0.251 0.043 Example 5 Sample Experiment Absorbance A5 0.298 0.260 0.038 Comparative Example 1 Sample Experimental Absorbance A6 0.301 0.245 0.056 Comparative Example 2 Sample Experimental Absorbance A7 0.294 0.239 0.055 Comparative Example 3 Sample Experimental Absorbance A8 0.302 0.250 0.052 Comparative Example 4 Sample Experimental Absorbance A9 0.298 0.248 0.050

[0277] in,

[0278] ΔA calculation formula:

[0279] ΔA=A(0min)-A(60min)

[0280] 5α-reductase activity inhibition rate calculation formula:

[0281] 5α-reductase activity inhibition rate (%) = (ΔA0-ΔAn) / ΔA0×100%

[0282] Where: ΔA1-negative experiment absorbance difference

[0283] ΔA2-difference in absorbance of sample test

[0284] Table 2 5α-reductase activity inhibition test results

[0285] 5α-reductase activity inhibition rate Example 1 Sample 43.8％ Example 2 Sample 47.5％ Example 3 Sample 48.8％ Example 4 Sample 46.3％ Example 5 Sample 52.5％ Comparative Example 1 Sample 30.0％ Comparative Example 2 Sample 31.3％ Comparative Example 3 Sample 35.0％ Comparative Example 4 Sample 37.5％

[0286] According to the test results in Tables 1-2 above, it can be seen that the anti-hair loss and oil-control compositions prepared in Examples 1-5 of the present invention have better 5α-reductase activity inhibition effects, with inhibition rates of more than 40% and the highest reaching more than 52.5%. This indicates that the shampoo compositions prepared in Examples 1-8 of the present invention all have good oil-control effects.

[0287] In Comparative Examples 1-2, omitting sophorolipids or Platycladus orientalis leaf extract would affect the inhibition rate of the anti-hair loss and oil control composition on 5α-reductase activity, thereby significantly reducing the inhibitory effect of 5α-reductase activity.

[0288] Comparative Example 3-4: Changing the mass ratio of Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid is not within the scope of protection of this application and does not affect the interaction between Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid, thereby reducing the inhibitory effect of the composition on 5α-reductase activity.

[0289] 2. Antibacterial test

[0290] 2.1 Test purpose and principle:

[0291] Recent studies have found that the massive reproduction of Malassezia furfur on the scalp can cause excessive proliferation of the scalp's stratum corneum, thereby prompting the abnormal shedding of stratum corneum cells in the form of white or gray scales. This scale is dandruff. The massive reproduction of Malassezia furfur is one of the important factors causing dandruff.

[0292] This study conducted an inhibition ring test to observe the in vitro antibacterial activity of antidandruff shampoos against Malassezia, a common fungus on the surface of seborrheic dermatitis lesions, to indirectly evaluate the antidandruff efficacy of hair products.

[0293] This test method is an in vitro method and is suitable for evaluating the anti-dandruff effect of dandruff caused by Malassezia. This method is not applicable to the evaluation of the anti-dandruff effect of the test sample on dandruff caused by other factors.

[0294] 2.2 Judgment criteria

[0295] If the diameter of the inhibition ring of the sample against Malassezia furfur is greater than 7 mm, the product has an anti-dandruff effect; if the diameter of the inhibition ring of the sample against Malassezia furfur is less than or equal to 7 mm, the product has no anti-dandruff effect.

[0296] 2.3 Test methods

[0297] (1) Place 20 μl of sample solution on a 5 mm filter paper to prepare a test piece.

[0298] (2) Using 5×10 5 -5×10 6 A suspension of Malassezia furfur (ATCC 44344) at cfu / mL was evenly spread on the surface of a Leeming & Notman medium plate to prepare a contaminated plate.

[0299] (3) Place the test piece on the contaminated plate, place it in a 30°C incubator, incubate for 7 days, and observe the results.

[0300] The diameter of the inhibition ring was measured with a vernier caliper and recorded. The test was repeated four times in parallel and the average value was taken.

[0301] The test results are shown in Table 3 below.

[0302] Table 3 Inhibition zone diameter test results

[0303] Diameter of inhibition zone (mm) Example 1 Sample 10.25 Example 2 Sample 10.86 Example 3 Sample 10.56 Example 4 Sample 11.05 Example 5 Sample 11.28 Comparative Example 1 Sample 7.54 Comparative Example 2 Sample 7.82 Comparative Example 3 Sample 8.28 Comparative Example 4 Sample 8.35

[0304] According to the test results in Table 3 above, it can be seen that the anti-hair loss and oil control compositions prepared in Examples 1-5 of the present invention have better antibacterial effects, with the diameter of the inhibition zone reaching more than 10 mm, and the highest reaching more than 11 mm, indicating that the shampoo compositions prepared in Examples 1-8 of the present invention all have good antibacterial effects.

[0305] Omitting sophorolipids or Platycladus orientalis leaf extract in Comparative Examples 1-2 would affect the antibacterial effect of the anti-hair loss and oil control composition, resulting in a significant decrease in the diameter of the inhibition zone.

[0306] Comparative Example 3-4: Changing the mass ratio of Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid is not within the scope of protection of this application and does not affect the interaction between Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid, thereby improving the antibacterial effect of the composition.

[0307] Application Example 1: An anti-hair loss and oil-control shampoo and its preparation method

[0308] It is composed of the components in parts by weight of Table 4:

[0309] Table 4

[0310]

[0311] The preparation method comprises the following steps:

[0312] (1) Place water (80% total water content), surfactant 1, and hair conditioner 7 into a stirring pot and heat to 80-85° C. while stirring until all the ingredients are dissolved to obtain mixture 1;

[0313] (2) Mix hair conditioner 6 and heat at 85°C until completely dissolved. Then add surfactant 2 and thickener 2 and heat and stir for 30 minutes until all the ingredients are dissolved to obtain mixture 2.

[0314] (3) Cooling the mixture 2 to below 45° C., adding hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, the anti-hair loss and oil control composition, and hair conditioner 7, and homogenizing and stirring to obtain a mixture 3;

[0315] (4) After the piroctone olamine salt and the remaining water are mixed and dispersed, the remaining raw materials are added in sequence and homogenized for 3 minutes at a homogenization speed of 45 rpm until no solid particles are present, to obtain a mixture 4;

[0316] (5) At 45°C, mixture 3 was added to mixture 1 and stirred evenly, and then mixture 4 was added and stirred until uniform. The mixture was cooled to room temperature to obtain the anti-hair loss and oil control shampoo.

[0317] Application Example 2: An anti-hair loss and oil-control shampoo and its preparation method

[0318] It is composed of the components in parts by weight of Table 5:

[0319] Table 5

[0320]

[0321]

[0322] The preparation method comprises the following steps:

[0323] (1) Place water (80% total water content), surfactant 1, and hair conditioner 7 into a stirring pot and heat to 80-85° C. while stirring until all the ingredients are dissolved to obtain mixture 1;

[0324] (2) Mix hair conditioner 6 and heat at 85°C until completely dissolved. Then add surfactant 2 and thickener 2 and heat and stir for 30 minutes until all the ingredients are dissolved to obtain mixture 2.

[0325] (3) Cooling the mixture 2 to below 45° C., adding hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, the anti-hair loss and oil control composition, and hair conditioner 7, and homogenizing and stirring to obtain a mixture 3;

[0326] (4) After the piroctone olamine salt and the remaining water are mixed and dispersed, the remaining raw materials are added in sequence and homogenized for 3 minutes at a homogenization speed of 45 rpm until no solid particles are present, to obtain a mixture 4;

[0327] (5) At 45°C, mixture 3 was added to mixture 1 and stirred evenly, and then mixture 4 was added and stirred until uniform. The mixture was cooled to room temperature to obtain the anti-hair loss and oil control shampoo.

[0328] Application Example 3: An anti-hair loss and oil-control shampoo and its preparation method

[0329] It is composed of the components in parts by weight of Table 6:

[0330] Table 6

[0331]

[0332]

[0333] The preparation method comprises the following steps:

[0334] (1) Place water (80% total water content), surfactant 1, and hair conditioner 7 into a stirring pot and heat to 80-85° C. while stirring until all the ingredients are dissolved to obtain mixture 1;

[0335] (2) Mix hair conditioner 6 and heat at 85°C until completely dissolved. Then add surfactant 2 and thickener 2 and heat and stir for 30 minutes until all the ingredients are dissolved to obtain mixture 2.

[0336] (3) Cooling the mixture 2 to below 45° C., adding hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, the anti-hair loss and oil control composition, and hair conditioner 7, and homogenizing and stirring to obtain a mixture 3;

[0337] (4) After the piroctone olamine salt and the remaining water are mixed and dispersed, the remaining raw materials are added in sequence and homogenized for 3 minutes at a homogenization speed of 45 rpm until no solid particles are present, to obtain a mixture 4;

[0338] (5) At 45°C, mixture 3 was added to mixture 1 and stirred evenly, and then mixture 4 was added and stirred until uniform. The mixture was cooled to room temperature to obtain the anti-hair loss and oil control shampoo.

[0339] Application Example 4: An anti-hair loss and oil-control shampoo and its preparation method

[0340] It is composed of the components in parts by weight of Table 7:

[0341] Table 7

[0342]

[0343] The preparation method comprises the following steps:

[0344] (1) Place water (80% total water content), surfactant 1, and hair conditioner 7 in a stirring pot and heat to 80-85° C. while stirring until all the ingredients are dissolved to obtain mixture 1;

[0345] (2) Mix hair conditioner 6 and heat at 85°C until completely dissolved. Then add surfactant 2 and thickener 2 and heat and stir for 30 minutes until all the ingredients are dissolved to obtain mixture 2.

[0346] (3) Cooling the mixture 2 to below 45° C., adding hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, the anti-hair loss and oil control composition, and hair conditioner 7, and homogenizing and stirring to obtain a mixture 3;

[0347] (4) After the piroctone olamine salt and the remaining water are mixed and dispersed, the remaining raw materials are added in sequence and homogenized for 3 minutes at a homogenization speed of 45 rpm until no solid particles are present, to obtain a mixture 4;

[0348] (5) At 45°C, mixture 3 was added to mixture 1 and stirred evenly, and then mixture 4 was added and stirred until uniform. The mixture was cooled to room temperature to obtain the anti-hair loss and oil control shampoo.

[0349] Application Comparative Example 1:

[0350] The difference from Application Example 1 is that no anti-hair loss and oil control composition is added, and the content of hair conditioner 1 is increased to 4.1%, as shown in Table 8 below.

[0351] Table 8

[0352]

[0353]

[0354] The preparation method is the same as that of Application Example 1 (removal of the anti-hair loss and oil control composition).

[0355] Application Comparative Example 2:

[0356] The difference from Application Example 1 is that the anti-hair loss and oil-control composition is replaced by the anti-hair loss and oil-control composition in Comparative Example 1, as shown in Table 9 below.

[0357] Table 9

[0358]

[0359] The preparation method is the same as that of Application Example 1.

[0360] Application Comparative Example 3:

[0361] The difference from Application Example 1 is that the anti-hair loss and oil control composition is replaced by the anti-hair loss and oil control composition in Comparative Example 2, as shown in Table 10 below.

[0362] Table 10

[0363]

[0364] The preparation method is the same as that of Application Example 1.

[0365] Effect experiment:

[0366] 1. Oil control efficacy evaluation experiment

[0367] (1) Test principle

[0368] The Sebumeter SM815 is used to test the oil content of the skin. It is based on the principle of photometry. A special 0.1mm thick matte tape absorbs oil from the human skin and becomes translucent. The light transmittance changes. The more oil it absorbs, the greater the light transmittance. This allows the oil content of the skin to be measured.

[0369] (2) Test method

[0370] 70 subjects with oily scalps were randomly selected from a hair salon in a shopping mall, with 10 subjects in each group. The subjects used the shampoos of Application Examples 1-4 and Application Comparative Examples 1-3, washing their hair every two days for four consecutive weeks. The scalp oil content was measured using a Sebumeter SM815 oil tester, and the data were recorded as D0. The scalp oil content was also measured in a constant temperature laboratory 2 hours after washing on the 14th and 28th days, and the data were recorded as D14 and D28. The oil content change rate on D14 and D28 was calculated according to the following formula:

[0371] Grease content change rate = {(grease content after sample use - grease content before sample use) / grease content before sample use} × 100%. The test results are shown in Table 11 below.

[0372] Table 11 Change rate of oil content of shampoos prepared by application examples 1-4 and application comparative examples 1-3

[0373] 14-day oil content change rate % 28-day oil content change rate % Application Example 1 -26.2 -35.1 Application Example 2 -23.5 -32.4 Application Example 3 -24.3 -31.5 Application Example 4 -25.6 -32.8 Comparative Application Example 1 -15.6 -16.9 Application Comparative Example 2 -18.9 -22.4 Application Comparative Example 3 -19.2 -24.3

[0374] According to the test data in Table 10 above,

[0375] The shampoo prepared by using Examples 1-4 of the present invention has a better oil control effect. On the one hand, the anti-hair loss and oil control composition prepared by the present invention is adopted, wherein the flavonoids in the Platycladus orientalis leaf extract can effectively control the secretion of 5a-reductase, thereby controlling the secretion of scalp oil; sophorolipids are plant glycolipids of natural origin, which can deeply clean the scalp with extremely low surface tension; disodium azelaic acid can stabilize the sebaceous glands, and is actually stable, thereby reducing oil secretion. The present invention mixes and compounds Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid, and by controlling their mass ratio, the obtained anti-hair loss and oil control composition has a better oil control effect, thereby improving the scalp microenvironment and reducing hair loss; on the other hand, the present invention uses a variety of skin conditioners, i.e., a variety of plant extracts, and the interaction of the plant extracts enables the obtained shampoo to have a better oil control effect.

[0376] In Comparative Example 1, no anti-hair loss and oil control composition was added, and the resulting shampoo had a significantly reduced oil control effect. In Comparative Examples 2-3, varying the specific ingredients of the anti-hair loss and oil control composition affected the interactions between the anti-hair loss and oil control compositions to a certain extent, thereby reducing the oil control effect.

[0377] 2. Satisfaction evaluation

[0378] Experimental method: 7 groups of volunteers were selected, with 3 volunteers in each group using the shampoo of Application Examples 1-4 and Comparative Examples 1-3, respectively, with a washing frequency of 2 days / time for 4 consecutive weeks. During the experimental period, the volunteers did not use shampoo with other ingredients.

[0379] After 4 weeks, volunteers evaluated the oil control effect, itching effect, and anti-hair loss effect. The evaluation criteria are as follows:

[0380] Oil control effect: 4-5 points: The water and oil of the scalp are balanced. When washing your hair 2 times a day, there is no excessive oil production, and the hair can stay fluffy for 2 days or more; 3-4 points: The oil production of the scalp is significantly reduced. When washing your hair 2 times a day, the hair can stay fluffy for 1.5-2 days; 2-3 points: The oil production of the scalp is reduced. When washing your hair 2 times a day, the hair can stay fluffy for 1-1.5 days; 1-2 points: The oil production of the scalp is partially reduced. When washing your hair 2 times a day, the hair can stay fluffy for 0.5-1 day; 0-1 point: The oil production of the scalp is slightly reduced. When washing your hair 2 times a day, the hair only stays fluffy for about 0.5 day.

[0381] Antipruritic effect: 4-5 points: no scalp itching; 3-4 points: significant reduction in scalp itching; 2-3 points: some reduction in scalp itching; 1-2 points: little reduction in scalp itching; 0-1 point: no reduction in scalp itching.

[0382] Anti-hair loss effect: 4-5 points: Hair loss is significantly reduced, and hair becomes noticeably thicker; 3-4 points: Hair loss is reduced, and hair becomes thicker; 2-3 points: The effect of reducing hair loss is not obvious, and the effect of thickening hair is not obvious; 1-2 points: The amount of hair loss has not decreased; 0-1 point: The amount of hair loss has increased.

[0383] The specific evaluation structure is shown in Table 12 below.

[0384] Table 12 Scoring results

[0385]

[0386]

[0387] The scoring results in Table 11 above indicate that the shampoos prepared using Examples 1-4 exhibited excellent oil control, antipruritic, and anti-hair loss effects. In contrast, omitting the anti-hair loss control composition or modifying the specific ingredients of the anti-hair loss control composition in Comparative Examples 1-3 affected the oil control, antipruritic, and anti-hair loss effects of the shampoos, consistent with the aforementioned oil control and antibacterial effect test results.

[0388] Obviously, the described embodiments are only individual embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other implementations obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

Claims

1. An anti-hair loss and oil control composition, characterized in that: The invention comprises the following components: Platycladus orientalis leaf extract, sophorolipid, disodium azelaic acid, a moisturizer and water; the mass ratio of the Platycladus orientalis leaf extract, sophorolipid and disodium azelaic acid is 0.8-1.2:1.0-1.5:1.0-1.

5.

2. The anti-hair loss and oil control composition according to claim 1, wherein: The mass ratio of the Platycladus orientalis leaf extract, sophorolipid and disodium azelaic acid is 0.9-1.1:1.1-1.4:1.1-1.

4.

3. The anti-hair loss and oil control composition according to claim 1, wherein: The mass ratio of the Platycladus orientalis leaf extract, sophorolipids and disodium azelaic acid is 1:1.2:1.

2.

4. The anti-hair loss and oil control composition according to claim 1, wherein: The anti-fat loss and oil control composition comprises the following components by weight percentage: 8-12% of Platycladus orientalis leaf extract, 10-15% of sophorolipids, 10-15% of disodium azelaic acid, 20-40% of glycerol and the balance of water.

5. The anti-hair loss and oil control composition according to claim 4, characterized in that: The anti-fat loss and oil control composition comprises the following components by weight percentage: Platycladus orientalis leaf extract 10%, sophorolipids 12%, disodium azelaic acid 12%, glycerol 30% and water as the balance.

6. The method for preparing the anti-hair loss and oil control composition according to any one of claims 1 to 5, characterized in that: The following steps are involved: (1) mixing glycerol and water to obtain a mixture; (2) Adding Platycladus orientalis leaf extract, sophorolipids, and disodium azelaic acid to the mixture obtained in step (1) in sequence to obtain the anti-hair loss and oil control composition.

7. Use of the anti-hair loss and oil control composition according to any one of claims 1 to 5 in the preparation of shampoo and hair care products.

8. An anti-hair loss and oil-control shampoo, characterized by: The invention comprises the anti-hair loss and oil control composition according to any one of claims 1 to 5 and auxiliary materials.

9. The anti-hair loss and oil-control shampoo according to claim 8, characterized in that: The auxiliary materials include one or more of a hair conditioner, a surfactant, a thickener, a preservative, a fragrance, an antidandruff agent, a pH adjuster and a colorant.

10. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The hair conditioner includes a hair conditioner 1, which is selected from one or more of ginger root extract, ginseng root extract, kelp extract, grapefruit seed extract, Centella asiatica extract and rice bran extract.

11. The anti-hair loss and oil-control shampoo according to claim 10, characterized in that: The hair conditioner 1 is a mixture of ginger root extract, ginseng root extract, kelp extract, grapefruit seed extract, Centella asiatica extract and rice bran extract.

12. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The hair conditioner also includes hair conditioner 2, which is aloe vera leaf extract.

13. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The hair conditioner further comprises a hair conditioner 3, which is a ginseng root extract.

14. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The hair conditioner also includes hair conditioner 4, which is witch hazel flower extract.

15. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The hair conditioner also includes a hair conditioner 5, which is polyquaternium-10.

16. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The hair conditioner also includes hair conditioner 6, which is a Ligusticum chuanxiong extract.

17. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The hair conditioner also includes hair conditioner 7, which is di(PPG-2 myristeth-10) adipate.

18. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The surfactant includes surfactant 1, and the surfactant 1 is sodium lauryl polyether sulfate.

19. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The surfactant includes surfactant 2, and the surfactant 2 is sodium 2-methyl sulfolaurate.

20. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The thickener includes thickener 1, and the thickener 1 is sodium chloride.

21. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The thickener further comprises thickener 2, and the thickener 2 is cocamide MEA.

22. The anti-hair loss and oil-control shampoo according to claim 9, characterized in that: The composition comprises the following components by weight percentage: 0.8-3% of an anti-hair loss and oil control composition, 5-15% of a hair conditioner, 15-25% of a surfactant, 1-5% of a thickener, 0.5-1.0% of a preservative, 0.1-0.6% of a fragrance, 0.1-0.5% of an anti-dandruff agent, 0.1-0.3% of a pH conditioner, 0.04-0.08% of a colorant and the balance being water.

23. The anti-hair loss and oil-control shampoo according to claim 22, characterized in that: The composition comprises the following components by weight percentage: 1.0-2% of an anti-hair loss and oil control composition, 10-12% of a hair conditioner, 15-20% of a surfactant, 2-4% of a thickener, 0.6-0.9% of a preservative, 0.2-0.5% of a fragrance, 0.2-0.4% of an anti-dandruff agent, 0.2-0.3% of a pH conditioner, 0.05-0.07% of a colorant and the balance being water.

24. The anti-hair loss and oil-control shampoo according to claim 23, characterized in that: The hair conditioner is a mixture of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7, with a mass ratio of 2-5:1-3:1-3:1-3:0.1-0.5:0.1-0.5:0.1-0.

3.

25. The anti-hair loss and oil-control shampoo according to claim 24, characterized in that: The mass ratio of hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, hair conditioner 5, hair conditioner 6 and hair conditioner 7 is 3:2.6:2.6:2.6:0.35:0.3:0.

15.

26. The anti-hair loss and oil-control shampoo according to claim 23, characterized in that: The surfactant is a mixture of surfactant 1 and surfactant 2; the mass ratio is 6-10:

1.

27. The anti-hair loss and oil-control shampoo according to claim 23, characterized in that: The thickener is a mixture of thickener 1 and thickener 2; the mass ratio is 1-3:

1.

28. The anti-hair loss and oil control shampoo according to any one of claims 8 to 22, characterized in that: The anti-hair loss and oil control shampoo comprises the following components by weight percentage: Anti-hair loss and oil control composition 1.1%, HYFTGF003 3%, HYABW01 2.6%, ginseng root extract 2.6%, HYHVFW01 2.6%, SY-400 0.35%, Chuanxiong extract 0.3%, di(PPG-2 myristeth-10) adipate 0.15%, Texapon N 70 16%, MES 2%, sodium chloride 2.5%, Comperlan CMEA 1.2%, phenoxyethanol 0.5%, sodium benzoate 0.4%, FH20431449 0.4%, OCT 0.3%, citric acid 0.2%, caramel color 0.06% and water as the balance.

29. The method for preparing the anti-hair loss and oil-control shampoo according to any one of claims 9 to 28, characterized in that: The steps include: (1) Place water (80% total water content), surfactant 1, and hair conditioner 7 into a stirring pot and heat to 80-85° C. while stirring until all the ingredients are dissolved to obtain mixture 1; (2) Mix hair conditioner 6 and heat at 85°C until completely dissolved. Then add surfactant 2 and thickener 2 and heat and stir for 30 minutes until all the ingredients are dissolved to obtain mixture 2. (3) Cooling the mixture 2 to below 45° C., adding hair conditioner 1, hair conditioner 2, hair conditioner 3, hair conditioner 4, the anti-hair loss and oil control composition, and hair conditioner 7, and homogenizing and stirring to obtain a mixture 3; (4) After the piroctone olamine salt and the remaining water are mixed and dispersed, the remaining raw materials are added in sequence and homogenized for 3 minutes at a homogenization speed of 45 rpm until no solid particles are present, to obtain a mixture 4; (5) At 45°C, mixture 3 was added to mixture 1 and stirred evenly, then mixture 4 was added and stirred until evenly mixed, and the mixture was cooled to room temperature to obtain the anti-hair loss and oil control shampoo.

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