Active compound for predicting, forecasting, preventing and treating oriental migratory locust and application method thereof

By collecting and identifying compounds of East Asian mavericks in all ages, using their attraction or repelling properties, we develop methods for insect prediction, forecasting and control, and solve the negative impact of chemical pesticide prevention and control on the environment, and achieve environmentally friendly and efficient East Asian mavericks prevention and control.

CN120458101APending Publication Date: 2025-08-12INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI
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Patent Information

Application Number
CN202411785431.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-30
Publication Date
2025-08-12

AI Technical Summary

Technical Problem

In the prior art, chemical pesticides have negative impacts on the environment and lack effective early prediction and forecasting methods.

Method used

By collecting and identifying 20 compounds released by East Asian migratory locusts at different ages, using the attraction or repelability of these compounds, methods for insect prediction and control, including the use of specific proportions of mixed compounds for trapping or repelling.

Benefits of technology

Effective control of East Asian locusts has been achieved, reducing their number, protecting crops, and reducing negative impacts on the environment.

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Abstract

The invention provides a high-activity compound for predicting, forecasting, preventing and treating oriental migratory locust and an application method of the high-activity compound. In the research, 20 compounds released by oriental migratory locust at different ages and at each stage are collected and identified, including butyl ethyl ether, benzothiazole, beta-homocyclic citral, 3-methylcyclopentanol, 2, 3, 4-trimethyl-1, 3-pentanediol, 2, 3, 4-trimethyl-1, 3-pentanediol and 2, 3, 4-trimethyl-1, 3-pentanediol. The invention relates to an anti-aging and anti-aging agent which is prepared from 2, 6-diisopropylnaphthalene, beta-ionone, acetophenone, D-limonene, trans-2-decenal, beta-cyclocitral, 4-methyl-2-pentanol, methyl benzoate, menthol, benzaldehyde, phenylacetonitrile, nonanal, 2-heptanone, 2, 5-dimethylpyrazine, 1, 3-dimethyluracil, dihydroactinidiolide and the like. The strong attraction or repelling effect is realized in each age. When the compounds are used independently or 2-20 compounds are mixed according to a certain proportion, the gathering or repelling effect can be achieved. The method can be used for predicting and forecasting field insect conditions, preventing and controlling oriental migratory locusts and the like.
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Description

Technical Field

[0001] The present invention relates to the field of agricultural plant protection, particularly to the control and prediction of the East Asian migratory locust. By analyzing specific pheromones released by insects, it can be used for insect prediction and prediction, as well as combined with pesticides for control. The present invention provides a method for effectively controlling the East Asian migratory locust by utilizing pheromones secreted by the insects themselves. Background Art

[0002] The East Asian migratory locust is a pest that causes serious damage to crops. There are two generations a year in the Huanghuai River Basin, 2-3 generations in the middle and lower reaches of the Yangtze River, 3 generations in South China, and 4 generations in Hainan. Traditional prevention and control methods include spraying chemical pesticides, but these methods may have negative effects on the environment and ecosystem. Early prediction and forecasting can buy time for locust prevention and control. Therefore, it is of great significance to find a low-stage collective pheromone for early prediction and forecasting, which can be more environmentally friendly and efficient. The present invention studies the specific pheromones released by insects during their growth process for communication within their own population and with other organisms in the environment, and develops a bioactive substance released by locusts at various stages. By analyzing its physiological activity, it is applied to prediction and forecasting and effective prevention and control methods to achieve effective control of the East Asian migratory locust. Summary of the Invention

[0003] The present invention provides highly active compounds and their application methods for predicting, forecasting, and controlling the East Asian migratory locust. In this study, we collected and identified 20 compounds released by different instars of the East Asian migratory locust, including butyl ethyl ether, benzothiazole, β-homocyclocitral, 3-methylcyclopentanol, 2,6-diisopropylnaphthalene, β-ionone, acetophenone, D-limonene, trans-2-decenal, β-cyclocitral, 4-methyl-2-pentanol, methyl benzoate, menthol, benzaldehyde, phenylacetonitrile, nonanal, 2-heptanone, 2,5-dimethylpyrazine, 1,3-dimethyluracil, and dihydroactinol. These compounds strongly attract or repel all instars. These compounds, used individually or in mixtures of 2 to 20 in specific proportions, can achieve a potent or repellent effect. They can be used for field prediction and forecasting of insect infestations and for East Asian migratory locust control.

[0004] The principle of attraction and repellency is to decipher the chemical language of insects and use the substances they secrete for communication to trap (with attractive compounds) and repel (stay away from crops with repellent compounds). BRIEF DESCRIPTION OF THE DRAWINGS

[0005] Figure 1 The results are as follows: the collective effect of 3-methylcyclopentanol, 4-methyl-2-pentanol and benzaldehyde in a ratio of 1:1:1 on first-instar locusts (n-hexane was used as the control);

[0006] Figure 2 The aggregation effect of 3-methylcyclopentanol on 2nd instar locusts (n-hexane as control)

[0007] Figure 3 This is the collective effect of heptanone and 2,5-dimethylpyrazine 2:1 on third-instar locusts (n-hexane is the control);

[0008] Figure 4 The results are as follows: the collective effect of benzaldehyde and benzyl cyanide (2:3) on 4th instar locusts (n-hexane is the control);

[0009] Figure 5 The results are as follows: the aggregation effect of 2-heptanone and benzyl cyanide (4:3) on 5th instar locusts (n-hexane was used as the control);

[0010] Figure 6 The repellent effect of dihydroactinolide on third-instar locusts (n-hexane was used as the control);

[0011] Figure 7 The repellent effect was obtained by the mixture of butyl ethyl ether, 2,6-diisopropylnaphthalene, β-ionone, and methyl benzoate in a ratio of 1:2:2:3 (n-hexane was used as the control). DETAILED DESCRIPTION

[0012] Example 1: Trapping effectiveness against 1-year-old locusts: Mix 3-methylcyclopentanol, 4-methyl-2-pentanol, and benzaldehyde in a 1:1:1 molar ratio, adding 0.01 mol of each to 10 mL of n-hexane. Place the mixture in a field trap and place it in a cornfield. Use it to trap 1-3-year-old East Asian migratory locusts in the field to reduce their population.

[0013] Example 2: Trapping effect on 2-year-old locusts: Dissolve 0.01 mol of 3-methylcyclopentanol in 10 mL of n-hexane. Place the solution in a field trap and place it in a cornfield. Use this trap to trap 1-5 stages of the East Asian migratory locust, thereby reducing its population.

[0014] Example 3: Trapping effect on 3-year-old locusts: Dissolve 0.01 mol of 3-methylcyclopentanol in 10 mL of n-hexane. Place the solution in a field trap and place it in a cornfield. Use this trap to trap 1-5 stages of the East Asian migratory locust, thereby reducing its population.

[0015] Example 4: Repellent Effect: 0.03 mol of dihydroactinolide was dissolved in n-hexane, and appropriate surfactants and xylene were added to prepare a 1% emulsifiable concentrate. This was diluted 1000-fold and sprayed on a millet field infested with a small number of East Asian migratory locusts. It was found to have a significant repellent effect against 3- to 5-year-old larvae and adults of the East Asian migratory locust, protecting millet from locust damage.

Claims

1. A bioactive compound and composition thereof for controlling and predicting East Asian migratory locusts, characterized in that: The compounds include but are not limited to butyl ethyl ether, benzothiazole, β-homocyclic citral, 3-methylcyclopentanol, 2,6-diisopropylnaphthalene, β-ionone, acetophenone, D-limonene, trans-2-decenal, β-cyclocitral, 4-methyl-2-pentanol, methyl benzoate, menthol, benzaldehyde, phenylacetonitrile, nonanal, 2-heptanone, 2,5-dimethylpyrazine, 1,3-dimethyluracil, dihydroactinol, etc.

2. The bioactive compound according to claim 1, characterized in that The compound and the composition thereof respectively exhibit strong attraction or repellency effects on adult male or female locusts at different instars of the East Asian migratory locust.

3. A method for controlling and predicting East Asian migratory locusts, characterized in that: Based on monitoring or control requirements, one or more of the above compounds are selected, including 2 to 20 compounds, and mixed in any proportion. The selected compounds are applied to the field to achieve the goal of predicting and controlling the East Asian migratory locust through trapping or repelling, thereby reducing the damage caused by the East Asian migratory locust to crops.

4. The method according to claim 3, characterized in that Examples include: Example 1: 3-Methylcyclopentanol, 4-methyl-2-pentanol and benzaldehyde were mixed at a molar ratio of 1:1:1, 0.01 mol of each was placed, dissolved in 10 mL of n-hexane, loaded into a locust field trap, and placed in a grassland corn field to trap 1-3 instar East Asian migratory locusts. Example 2: 0.01 mol of 3-methylcyclopentanol was dissolved in 10 mL of n-hexane, loaded into a locust field trap, and placed in a grassland corn field to trap 1-5 instar East Asian migratory locusts. Example 3: 0.01 mol of 3-methylcyclopentanol was dissolved in 10 mL of n-hexane, loaded into a locust field trap, and placed in a grassland corn field to trap 1-5 instar East Asian migratory locusts. Example 4: 0.03 mol of dihydroactinol was dissolved in n-hexane, and appropriate surfactants, solvent xylene, etc. were added to prepare a 1% emulsifiable concentrate, which was diluted 1000 times and sprayed on a millet field with a small amount of East Asian migratory locusts to repel 3rd to 5th instar larvae and adults.

5. An active compound for predicting, forecasting and controlling East Asian migratory locust and its application method, characterized in that , the method comprises: Collect and identify 20 compounds released by the East Asian migratory locust at different age stages; use these compounds alone or in a mixture of 2 to 20 in a certain proportion to achieve aggregation or repellent effects; apply these compounds to insect infestation prediction and forecasting in the field, East Asian migratory locust prevention and control, etc.

6. A method for controlling and predicting East Asian migratory locusts in the field of agricultural plant protection, characterized in that: By studying the specific pheromones released by insects, we can apply them to prediction and effective prevention and control to achieve effective control of the East Asian migratory locust.