Lung tumor treatment device based on irreversible electroporation and cryoablation

Abstract

The invention relates to the technical field of medical instruments, in particular to a lung tumor treatment device based on irreversible electroporation and cryoablation, which comprises a single needle used for generating high-voltage electric pulse, an ice knife used for conveying a cold air medium and a CT display module used for displaying a CT image in real time, and further comprises a puncture cannula, the single needle and the ice skate blade are in clearance fit with the sliding groove; a needle head is detachably connected in the sliding groove, a conveying pipe is communicated in the puncture cannula, and an output port for discharging a cold air medium is formed in one end of the puncture cannula; one side of the sliding groove further communicates with a collecting mechanism used for collecting external tissue, and the collecting mechanism is used for collecting the external tissue based on pushing of the needle head, the single needle and the ice skate blade. Operation tools can be conveniently switched, damage to peripheral tissues in the body in the process of treating the ground vitreous nodules is reduced, and the removing effect on the ground vitreous nodules is guaranteed.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a lung tumor treatment device based on irreversible electroporation and cryoablation. Background Art

[0002] Pulmonary ground-glass nodules (GGLs) are a type of cloud-like shadow with slightly increased density on chest CT scans. They are nodular (usually ≤3 cm in diameter). The nodules are named because they resemble ground glass and may be early tumors of benign or malignant lesions.

[0003] In the process of treating early-stage tumors, in addition to direct surgical resection, patients who cannot tolerate surgery or require palliative care can be treated with irreversible electroporation ablation or cryoablation. Traditional irreversible electroporation ablation usually uses multiple electrode needles to form an electric field to cover the tumor area, applying short, high-intensity electric pulses to the tumor tissue to form irreversible nanoscale pores in the cell membrane. Unlike traditional radiofrequency and microwave thermal ablation, irreversible electroporation ablation does not rely on high temperatures, but directly destroys the cell membrane through the action of the electric field, avoiding thermal damage to surrounding blood vessels, nerves, and bronchi. Cryoablation is a minimally invasive treatment technology that destroys tumor tissue at extremely low temperatures. Liquid nitrogen or argon gas is delivered to the tumor tissue through a probe to form a "nitrogen-argon knife" with a temperature of -140°C to -160°C, rapidly freezing tumor cells and causing ice crystals to form inside the cells, directly destroying the cell membrane and organelle structure. However, ice crystal formation may tear blood vessels and other surrounding tissues, causing bleeding. Secondly, cryoablation usually cannot obtain complete tumor tissue specimens, and it is difficult to confirm whether the tumor is completely inactivated through postoperative pathology. There is a risk of recurrence, but tumor antigens released by cryoablation can also be used to enhance the systemic immune response.

[0004] At the same time, because both irreversible electroporation and cryoablation require CT imaging for guidance, traditional irreversible electroporation and ablation techniques use multiple needle punctures, which involve a large puncture area and are not suitable for single-person operation. They are also not suitable for minor ground-glass nodules in the lungs. Therefore, single-needle bipolar electrode technology can be used to reduce tissue damage. However, high voltages can cause muscle spasms in the treatment area, often requiring anesthesia to control them. Cryoablation, on the other hand, produces low temperatures that temporarily paralyze nerves and provide significant intraoperative analgesia. The combined use of these two techniques can reduce the amount of anesthetics used during surgery, lowering the risk of side effects and accelerating postoperative recovery.

[0005] In addition, irreversible electroporation ablation technology originates from the physical destruction of cell membranes by electric fields (electroporation effect), rather than thermal energy. However, when electric current passes through surrounding tissues, due to the existence of resistance in the surrounding tissues, part of the electrical energy will be converted into thermal energy (Joule heat), resulting in a slight temperature rise. This can enhance the fragility of cell membranes at low temperatures treated by cryoablation technology and improve electroporation efficiency. The reheating formed by irreversible electroporation ablation technology can then be used to further tear the cell membranes and destroy the tumor tissue. Therefore, the present invention provides a lung tumor treatment device based on irreversible electroporation and cryoablation, which is convenient for treatment according to needs. A single needle for generating high-voltage electric pulses and a nitrogen-argon knife for delivering cold air are used alone or in combination to treat ground glass nodules in the lungs to ensure the treatment effect and reduce damage to surrounding tissues. Summary of the Invention

[0006] To solve the above problems, the present invention provides a lung tumor treatment device based on irreversible electroporation and cryoablation, which facilitates the switching of tools, reduces damage to surrounding tissues in the body during the treatment of ground-glass nodules in the lungs, and ensures the removal effect of ground-glass nodules in the lungs.

[0007] To achieve the above-mentioned objectives, the technical solution of the present invention is as follows: a lung tumor treatment device based on irreversible electroporation and cryoablation, comprising a single needle for generating high-voltage electric pulses, an ice knife for delivering a cold medium, and a CT display module for displaying CT images in real time, including a puncture cannula having a sliding groove formed therein, and the single needle and the ice knife both having a clearance fit within the sliding groove;

[0008] A needle is detachably connected to the sliding groove, a delivery tube is connected to the puncture sleeve, and an output port for discharging the cold air medium is opened at one end of the puncture sleeve;

[0009] One side of the sliding groove is also connected to a collection mechanism for collecting external tissues, and the collection mechanism is used to collect external tissues based on the push of a needle, a single needle and an ice knife.

[0010] Furthermore, the collection mechanism includes a mounting plate that is slidably engaged with the puncture cannula, a deformable stretching plate that is slidably engaged with the center of the mounting plate, one end of the stretching plate is hinged to the end of the mounting plate near the output port, the stretching plate and the mounting plate are slidably engaged, and a rubber block is fixedly connected to the side of the stretching plate away from the puncture cannula, the top of the rubber block is a vertical surface, and the bottom of the rubber block is an arcuate surface;

[0011] The ends of the single needle, the ice blade and the needle head close to the output port are all provided with matching grooves.

[0012] Furthermore, a plurality of scraping teeth are fixedly connected to both sides of the stretching sheet.

[0013] Furthermore, a spring is fixedly connected between the end of the stretching piece away from the output port and the mounting piece, and a shielding piece is fixedly connected to the end of the mounting piece close to the output port. The shielding piece is located between the stretching piece and the center of the puncture sleeve, and a collecting groove is opened on the side of the shielding piece close to the stretching piece.

[0014] A bimetallic strip is provided between the rubber block and the stretching strip, one end of the bimetallic strip is located in the rubber block, and the other end of the bimetallic strip is located in the stretching strip, and the thermal expansion coefficient of the bimetallic strip near the output port is greater than the thermal expansion coefficient of the bimetallic strip away from the output port.

[0015] Furthermore, an electromagnet is fixedly connected to one side of the single needle close to the matching slot, and the electromagnet is used to work based on the generation of high-voltage electric pulses;

[0016] When the electromagnet is working, the electromagnet and the rubber block are pressed against each other.

[0017] Furthermore, a temperature sensor is fixedly connected to the side of the stretch sheet away from the puncture cannula, and the temperature sensor is used to measure the temperature data of the surrounding tissue in real time and send the temperature data to the CT display module;

[0018] The CT display module is electrically connected to a processing module, which is used to record temperature data in real time and to enter the surgical process corresponding to the current time. The surgical process includes normal body temperature data during needle puncture, first reference data corresponding to the irreversible electroporation treatment process, and second reference data corresponding to the cryoablation treatment process. The temperature data is compared with the temperature data corresponding to the surgical process at the current time. If the current time is the needle puncture process, the temperature data at the current time is marked as normal body temperature data; if the current time is the irreversible electroporation treatment process, the temperature data is compared with the first reference data. If it meets the requirements, a continuous treatment display instruction is sent to the CT display module. If it does not meet the requirements, a continuous stop display instruction is sent to the CT display module. If the current time is the cryoablation treatment process, the temperature data is compared with the second reference data. If the temperature data is greater than or equal to the second reference data, an ablation completion instruction is sent to the CT display module; if the temperature data is less than the second reference data, an unthawed completion instruction is sent to the CT display module.

[0019] Furthermore, the delivery tube in the puncture sleeve is located around the installation piece.

[0020] Furthermore, a clamping block is fixedly connected to one end of the puncture sleeve close to the mounting plate, and an end of the matching groove away from the stretching plate is arc-shaped.

[0021] Furthermore, an isolation layer is provided at one end of the puncture sleeve close to the output port.

[0022] Furthermore, a side of the delivery tube close to the puncture sleeve is connected to a plurality of solenoid valves, the solenoid valves are electrically connected to the processing module, and the solenoid valves are evenly arranged in the length direction of the mounting plate.

[0023] The above scheme has the following beneficial effects:

[0024] 1. This protocol guides irreversible electroporation and cryoablation during CT ultrasound image display to ensure accurate positioning during the treatment of pulmonary ground-glass nodules. A puncture cannula provides an operating channel to facilitate the delivery of a single needle and an ice knife as needed, reducing damage to the patient caused by repeated punctures. It also facilitates repeated sampling and provides a basis for judging treatment outcomes.

[0025] 2. In this scheme, during the treatment process, the temperature of the tissue collected by the collection mechanism is maintained by a delivery tube to reduce the impact of temperature changes on the deformation of the tissue after treatment and reduce the damage to the original tissue. This provides a reference for the physician to understand the tissue judgment before and after treatment and facilitates the control of intraoperative parameters.

[0026] 3. In this solution, during the treatment process, the stretch sheet is extended to contact the surrounding tissue to form additional support to maintain the fixation of the puncture cannula, thereby reducing movement during the subsequent replacement of the single needle or ice knife and maintaining consistency during the treatment process.

[0027] Additional aspects and advantages of the present invention will be set forth in part in the description which follows and, in part, will be obvious from the description which follows, or may be learned by practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 An axonometric diagram of an embodiment of a lung tumor treatment device based on irreversible electroporation and cryoablation according to the present invention;

[0029] Figure 2 for Figure 1 Top view in ;

[0030] Figure 3 for Figure 2 Schematic diagram of the cross section along the AA direction;

[0031] Figure 4 for Figure 3 A magnified schematic diagram of part B in the middle;

[0032] Figure 5 This is a schematic diagram of the installation of an ice blade in an embodiment of a lung tumor treatment device based on irreversible electroporation and cryoablation according to the present invention;

[0033] Figure 6 Schematic diagram of single needle installation of an embodiment of a lung tumor treatment device based on irreversible electroporation and cryoablation according to the present invention;

[0034] Figure 7 This is a schematic diagram of a CT image of a puncture cannula during surgery in an embodiment of the lung tumor treatment device based on irreversible electroporation and cryoablation according to the present invention;

[0035] Figure 8 This is a schematic diagram of a postoperative healing CT image of an embodiment of the lung tumor treatment device based on irreversible electroporation and cryoablation of the present invention.

[0036] The figure marks in the drawings of the specification include: 1. puncture sleeve; 11. sliding groove; 12. output port; 13. delivery tube; 2. needle; 3. stretch plate; 30. mounting plate; 31. rubber block; 32. shielding plate; 4. single needle; 5. ice skate; 51. exhaust pipe; 6. matching groove; 61. electromagnet; 62. bimetallic strip. DETAILED DESCRIPTION

[0037] The technical solution of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the embodiments described are only some embodiments of the present invention, not all embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0038] In the description of the present invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings and are intended solely to facilitate and simplify the description of the present invention. They are not intended to indicate or imply that the devices or components referred to must have, be constructed, or operate in a specific orientation, and therefore should not be construed as limitations on the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0039] In the description of the present invention, it should be noted that, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood in a broad sense. For example, they may refer to fixed, detachable, or integral connections; mechanical or electrical connections; direct or indirect connections through an intermediate medium; and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on the specific circumstances.

[0040] The following is further described in detail through specific implementation methods:

[0041] Example 1:

[0042] As attached Figures 1 to 6Shown is a lung tumor treatment device based on irreversible electroporation and cryoablation, comprising a single needle 4 for generating high-voltage electric pulses, an ice knife 5 for delivering a cold medium, and a CT display module for displaying CT images in real time, including a puncture cannula 1, wherein a sliding groove 11 is formed in the puncture cannula 1, and the single needle 4 and the ice knife 5 both have a clearance fit in the sliding groove 11;

[0043] The needle 2 is detachably connected to the sliding groove 11, and the puncture sleeve 1 is connected to the delivery tube 13. An output port 12 for discharging the cold air medium is opened at one end of the puncture sleeve 1;

[0044] One side of the sliding groove 11 is also connected to a collection mechanism, which is used to collect external tissue based on the push of the needle 2, the single needle 4, and the ice knife 5. The collection mechanism includes a mounting plate 30 that slides with the puncture cannula 1. A deformable stretching plate 3 slides with the center of the mounting plate 30, and a plurality of scraping teeth are fixedly connected to both sides of the stretching plate 3. One end of the stretching plate 3 is hinged to the end of the mounting plate 30 near the output port 12. The stretching plate 3 slides with the mounting plate 30. The side of the stretching plate 3 away from the puncture cannula 1 is fixedly connected to a rubber block 31. The top of the rubber block 31 is a vertical surface, and the bottom of the rubber block 31 is an arcuate surface.

[0045] The single needle 4 , the ice blade 5 and the needle head 2 are all provided with a matching groove 6 at one end close to the output port 12 . The ice blade 5 is connected to an exhaust pipe 51 , and one end of the exhaust pipe 51 is located on the side of the ice blade 5 close to the output port 12 .

[0046] In this embodiment, a spring is fixedly connected between the end of the stretching piece 3 away from the output port 12 and the mounting piece 30, and a shielding piece 32 is fixedly connected to the end of the mounting piece 30 close to the output port 12. The shielding piece 32 is located between the stretching piece 3 and the center of the puncture sleeve 1, and a collecting groove is provided on the side of the shielding piece 32 close to the stretching piece 3; in another embodiment, the connection between the rubber block 31 and the stretching piece 3 is rotatably matched with a rotating shaft to enhance the rotation effect of the rubber block 31, so that the rubber block 31 no longer conflicts with the direct single needle 4 or the ice skate 5.

[0047] An isolation layer is provided at the end of the puncture sleeve 1 close to the output port 12; a bimetallic strip 62 is provided between the rubber block 31 and the stretch sheet 3, one end of the bimetallic strip 62 is located inside the rubber block 31, and the other end of the bimetallic strip 62 is located inside the stretch sheet 3, and the thermal expansion coefficient of the end of the bimetallic strip 62 close to the output port 12 is greater than the thermal expansion coefficient of the end of the bimetallic strip 62 away from the output port 12.

[0048] An electromagnet 61 is fixedly connected to one side of the single needle 4 close to the matching slot 6 . The electromagnet 61 is used to work based on the generation of high-voltage electric pulses. When the electromagnet 61 is working, the electromagnet 61 abuts against the rubber block 31 .

[0049] The specific implementation process is as follows:

[0050] During the CT ultrasound image display process, irreversible electroporation and cryoablation are guided to ensure the positioning accuracy during the treatment of ground-glass nodules in the lungs. The puncture cannula 1 is used to provide an operation channel, which facilitates the delivery of the single needle 4 and the ice knife 5 as needed, reducing damage to surrounding tissues in the body during the treatment of ground-glass nodules in the lungs. At the same time, it is convenient for repeated sampling and provides a basis for judging the treatment results.

[0051] Combined with Figure 7 As shown, during the movement of the single needle 4, the ice knife 5, and the needle 2 inside the puncture cannula 1, the needle 2 is used to puncture the body tissue, so that the puncture cannula 1 can be installed and replaced by the ice knife 5 and the single needle 4 to meet the needs of different surgical procedures. By utilizing the cooperation of the matching groove 6 and the rubber block 31, during the installation of the single needle 4, the ice knife 5, and the needle 2, the matching groove 6 is used to press against the vertical surface to push the stretching plate 3 for compression, so that the stretching plate 3 extends out of the puncture cannula 1 and comes into contact with the external tissue. This facilitates the acquisition of external tissue according to the movement and removal of the single needle 4, the ice knife 5, and the needle 2, so as to determine the corresponding tissue cells before treatment, after irreversible electroporation treatment, and after cryoablation treatment, and facilitates the confirmation of the surgical effect after treatment.

[0052] During treatment, the delivery tube 13 maintains the temperature of the tissue collected by the collection mechanism to reduce the impact of temperature changes on the post-treatment tissue deformation and damage to the original tissue. This provides a reference for the physician to understand the tissue before and after treatment and facilitates the control of intraoperative parameters. The scraper then scrapes the surrounding tissue to facilitate the collection and processing of the surrounding tissue, improving collection efficiency.

[0053] During the cryoablation process, the cold air medium discharged by the ice blade 5 is used to cool the surrounding tissues to form ice crystals. At the same time, after the bimetallic strip 62 is cooled, it is bent toward the end close to the output port 12, and the matching groove 6 is no longer in contact with the rubber block 31, so that the stretched spring drives the stretching sheet 3 to shrink, and the stretching sheet 3 is attached to the shielding sheet 32, so that the surrounding tissues are hidden in the collection groove, thereby realizing the collection of the surrounding tissues and facilitating the collection of tissue cells after cryoablation treatment.

[0054] When a high voltage electric pulse is generated during the bipolar energization process on the single needle 4, the isolation layer is used to reduce the influence of the electromagnetic field on the electromagnet 61 during operation, thereby ensuring the accurate reset of the stretching piece 3. At the same time, the electromagnet 61 is started to work, so that the electromagnet 61 adsorbs the magnetic metal of the bimetallic strip 62 inside the rubber block 31. For example, common active layer materials with high thermal expansion coefficients such as copper and manganese-nickel-copper alloys, common active layer materials with low thermal expansion coefficients such as iron and nickel-iron alloys, and iron is a magnetic metal that can be adsorbed by the magnetic force generated by the electromagnet 61, so that the bimetallic strip 62 drives the rubber block 31 to rotate inside the sliding groove 11, so that the rubber block 31 is no longer located inside the sliding groove 11, and the stretched spring is used to drive the stretching piece 3 to shrink, so that the stretching piece 3 is attached to the shielding piece 32, so that the surrounding tissue is hidden in the collection groove, so as to achieve the collection of the surrounding tissue, facilitate the collection of tissue cells after irreversible electroporation treatment, and ensure the removal effect of ground glass nodules of the lung (combined with Figure 7 and Figure 8 shown).

[0055] Example 2:

[0056] The difference from Example 1 is that a temperature sensor is fixedly connected to the side of the stretch sheet 3 away from the puncture sleeve 1. The temperature sensor is used to measure the temperature data of the surrounding tissue in real time and send the temperature data to the CT display module.

[0057] The CT display module is electrically connected to a processing module, which is used to record temperature data in real time and to enter the surgical process corresponding to the current time. The surgical process includes normal body temperature data during the needle 2 puncture process, the first reference data corresponding to the irreversible electroporation treatment process, and the second reference data corresponding to the cryoablation treatment process. The temperature data is compared with the temperature data corresponding to the surgical process at the current time. If the current time is the needle 2 puncture process, the temperature data at the current time is marked as normal body temperature data; if the current time is the irreversible electroporation treatment process, the temperature data is compared with the first reference data. If it meets the requirements, a continuous treatment display instruction is sent to the CT display module. If it does not meet the requirements, a continuous stop display instruction is sent to the CT display module; if the current time is the cryoablation treatment process, the temperature data is compared with the second reference data. If the temperature data is greater than or equal to the second reference data, an ablation completion instruction is sent to the CT display module; if the temperature data is less than the second reference data, an unthawed completion instruction is sent to the CT display module.

[0058] For example, the temperature data is compared and processed to display the patient's body temperature data so that the physician can determine whether the patient's body temperature is normal; during the irreversible electroporation treatment, the temperature data is compared with the first reference data to remind the physician that after the irreversible electroporation treatment is completed, the puncture cannula 1 is deepened and the single needle 4 is pulled back and pressed in to push the rubber block 31 through the matching groove 6 to extend the stretch sheet 3, and the stretch sheet 3 is used to collect biopsy tissue from the surrounding tissue to ensure the accuracy of the treatment results.

[0059] During the cryoablation treatment process, the temperature data is compared with the second reference data to remind the doctor whether the tissue in the body has completed tissue reheating and ablation, providing a reference basis for repeated cryoablation or guidance for the completion of cryoablation, which is convenient for the doctor to perform subsequent operations.

[0060] Example 3:

[0061] The difference from Example 2 is that the delivery tube 13 in the puncture cannula 1 is located around the mounting plate 30 .

[0062] The specific implementation process is as follows: Use the temperature sensor to measure and display the temperature of the surrounding tissue to regulate the temperature change of the liquid medium transported in the delivery tube 13, and maintain the temperature to reduce the impact of temperature on the collected tissue during different treatment processes, providing a reference basis for subsequent physicians' diagnosis and treatment decisions.

[0063] Example 4:

[0064] The difference from Example 3 is that a clamping block is fixedly connected to the end of the puncture sleeve 1 close to the mounting plate 30 , and the end of the matching groove 6 away from the stretching plate 3 is arc-shaped.

[0065] The specific implementation process is as follows: the position of the mounting plate 30 is limited by the clamping block to maintain the fixing effect on the stretching plate 3, so as to form unilateral retention during irreversible electroporation or cryoablation, so as to form a contrast effect, so that the physician can understand the tissue changes before and after the operation.

[0066] Example 5:

[0067] The difference from Example 4 is that a side of the delivery tube 13 close to the puncture cannula 1 is connected to a plurality of solenoid valves, which are electrically connected to the processing module and are evenly arranged along the length direction of the mounting plate 30 .

[0068] The specific implementation process is as follows: the processing module controls the opening and closing of the evenly arranged electromagnetic valves so that when the mounting plate 30 drives the stretching plate 3 to remove the sample, the delivery tube 13 is used to alternately discharge hot and cold media to kill the tissue that may remain in the puncture cannula 1, thereby reducing the contamination of the subsequent collected tissue and ensuring the accuracy of the subsequent biopsy process.

[0069] Obviously, the above embodiments are merely examples for clarity of explanation and are not intended to limit the implementation methods. Those skilled in the art will readily appreciate that other variations or modifications based on the above descriptions are possible. It is not necessary and impossible to enumerate all implementation methods here. Obvious variations or modifications arising therefrom remain within the scope of protection of the present invention.

Claims

1. A lung tumor treatment device based on irreversible electroporation and cryoablation, comprising a single needle (4) for generating high-voltage electric pulses, an ice knife (5) for delivering a cold medium, and a CT display module for displaying CT images in real time, characterized in that: The invention comprises a puncture sleeve (1), a sliding groove (11) is provided in the puncture sleeve (1), and the single needle (4) and the ice knife (5) are both clearance-matched with the sliding groove (11); A needle (2) is detachably connected to the sliding groove (11), a delivery tube (13) is connected to the puncture sleeve (1), and an output port (12) for discharging a cold air medium is opened at one end of the puncture sleeve (1); One side of the sliding groove (11) is also connected to a collection mechanism for collecting external tissues, and the collection mechanism is used to collect external tissues based on the push of the needle (2), the single needle (4) and the ice knife (5).

2. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 1, characterized in that: The collecting mechanism comprises a mounting plate (30) that is slidably engaged with the puncture sleeve (1); a deformable stretching plate (3) is slidably engaged with the center of the mounting plate (30); one end of the stretching plate (3) is hinged to an end of the mounting plate (30) close to the output port (12); the stretching plate (3) and the mounting plate (30) are slidably engaged; a rubber block (31) is fixedly connected to the side of the stretching plate (3) away from the puncture sleeve (1); the top of the rubber block (31) is a vertical surface, and the bottom of the rubber block (31) is an arcuate surface; The single needle (4), the ice blade (5) and the needle head (2) are all provided with a matching groove (6) at one end close to the output port (12).

3. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 2, characterized in that: A plurality of scraping teeth are fixedly connected to both sides of the stretching sheet (3).

4. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 3, characterized in that: A spring is fixedly connected between the end of the stretching piece (3) away from the output port (12) and the mounting piece (30), and a shielding piece (32) is fixedly connected to the end of the mounting piece (30) close to the output port (12). The shielding piece (32) is located between the stretching piece (3) and the center of the puncture sleeve (1), and a collecting groove is provided on the side of the shielding piece (32) close to the stretching piece (3); A bimetallic strip (62) is provided between the rubber block (31) and the stretching strip (3), one end of the bimetallic strip (62) is located in the rubber block (31), and the other end of the bimetallic strip (62) is located in the stretching strip (3), and the thermal expansion coefficient of the end of the bimetallic strip (62) close to the output port (12) is greater than the thermal expansion coefficient of the end of the bimetallic strip (62) away from the output port (12).

5. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 4, characterized in that: An electromagnet (61) is fixedly connected to one side of the single needle (4) close to the matching slot (6), and the electromagnet (61) is used to work based on the generation of high-voltage electric pulses; When the electromagnet (61) is working, the electromagnet (61) and the rubber block (31) are against each other.

6. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 5, characterized in that: A temperature sensor is fixedly connected to the side of the stretching sheet (3) away from the puncture sleeve (1), and the temperature sensor is used to measure the temperature data of the surrounding tissue in real time and send the temperature data to the CT display module; The CT display module is electrically connected to a processing module, and the processing module is used to record temperature data in real time and to input the surgical process corresponding to the current time. The surgical process includes normal body temperature data during the needle (2) puncture process, first reference data corresponding to the irreversible electroporation treatment process, and second reference data corresponding to the cryoablation treatment process. The temperature data is compared with the temperature data corresponding to the surgical process at the current time. If the current time is the needle (2) puncture process, the temperature data at the current time is marked as normal body temperature data; if the current time is the irreversible electroporation treatment process, the temperature data is compared with the first reference data. If they are consistent, a continuous treatment display instruction is sent to the CT display module. If they are not consistent, a continuous stop display instruction is sent to the CT display module. If the current time is the cryoablation treatment process, the temperature data is compared with the second reference data. If the temperature data is greater than or equal to the second reference data, an ablation completion instruction is sent to the CT display module; if the temperature data is less than the second reference data, an unthawed completion instruction is sent to the CT display module.

7. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 6, characterized in that: The delivery tube (13) in the puncture sleeve (1) is located around the mounting plate (30).

8. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 7, characterized in that: The end of the puncture sleeve (1) close to the mounting plate (30) is fixedly connected with a clamping block, and the end of the matching groove (6) away from the stretching plate (3) is arc-shaped.

9. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 8, characterized in that: An isolation layer is provided at one end of the puncture sleeve (1) close to the output port (12).

10. The lung tumor treatment device based on irreversible electroporation and cryoablation according to claim 9, characterized in that: A side of the delivery tube (13) close to the puncture sleeve (1) is connected to a plurality of electromagnetic valves, the electromagnetic valves are electrically connected to the processing module, and the electromagnetic valves are evenly arranged in the length direction of the mounting plate (30).

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