Concentration system for progesterone raw material production

Abstract

The invention provides a concentration system for progesterone raw material production. The concentration system comprises a concentration tank, the upper end of the concentration tank is communicated with a feeding pipe and a primary exhaust pipe, the concentration tank is sleeved with a heating cavity, the lower end of the concentration tank is communicated with a liquid discharge pipe, and an electromagnetic valve is arranged on the liquid discharge pipe; the device further comprises a second-stage concentration shell, a horizontally-arranged concentration roller is rotationally connected into the second-stage concentration shell, a rotating motor used for driving the concentration roller to rotate is installed outside the second-stage concentration shell, a strip-shaped liquid dipping groove is formed in the position, on one side of the upper portion of the concentration roller, in the second-stage concentration shell, and the lower end of a liquid discharging pipe extends into the second-stage concentration shell. A material storage tank is arranged below the concentration roller in the second-stage concentration shell, a scraping strip matched with the concentration roller is arranged below the strip-shaped liquid dipping tank in the second-stage concentration shell, and the upper end of the second-stage concentration shell is communicated with a second-stage exhaust pipe. Through the design of the concentration roller, the surface area of a solution can be increased during concentration, so that a solvent is evaporated more quickly, and the concentration efficiency is effectively improved.

Description

Technical Field

[0001] The invention belongs to the technical field of pharmaceutical equipment and relates to a concentration system for producing progesterone raw materials. Background Art

[0002] As a key progestogen, progesterone plays an indispensable role in reproductive medicine, gynecological treatments, and assisted reproductive technologies. As its application expands, so too do the requirements for progesterone raw material production processes. In progesterone production, the concentration step is a critical step in ensuring the quality and purity of the final product. This step removes organic solvents (such as ethanol, acetone, and ethyl acetate) used in the extraction process, thereby achieving a high concentration of the target product.

[0003] Progesterone extraction typically involves selecting from a variety of organic solvents, which are effective in extracting progesterone from natural sources or fermentation broths. However, after extraction, these solvents must be removed through a concentration process to increase the progesterone concentration. Currently, most progesterone manufacturers use a heating and concentration method to perform this operation.

[0004] Heating concentration is based on the principle of evaporation: by applying heat, the solvent molecules in the solution gain enough energy to overcome the attractive forces within the liquid and escape as gaseous molecules. In theory, evaporation primarily occurs at the surface of the liquid, where the molecules are directly exposed to air and are more likely to overcome the intermolecular attraction within the liquid and become gaseous molecules. Therefore, increasing the surface area of the liquid can accelerate the evaporation process, thereby speeding up concentration.

[0005] However, in practice, the surface area of the solution often cannot be expanded infinitely due to the limitations of the concentrator, resulting in slow evaporation of solvent molecules. This is especially true in large-scale industrial production, where the surface area of the solution is strictly limited to meet the design and operational requirements of production equipment, significantly reducing evaporation efficiency. Summary of the Invention

[0006] The object of the present invention is to provide a concentration system for producing progesterone raw materials, which can increase the surface area of the solution during concentration, enable the solvent to evaporate more quickly, and effectively improve the concentration efficiency.

[0007] To solve the above technical problems, the present invention provides a concentrating system for producing progesterone raw materials, comprising a concentrating tank, the upper end of which is connected to a feeding pipe, a primary exhaust pipe, and a backup pipe. A drive motor is mounted on the upper end of the concentrating tank, the power output shaft of the drive motor is connected to a stirring shaft extending into the concentrating tank, and an agitator is mounted on the stirring shaft. The concentrating tank is outer-circuited with a heating chamber, and the lower end of the concentrating tank is connected to a drain pipe, which is provided with a solenoid valve.

[0008] The invention also includes a secondary concentrating shell, wherein a horizontally arranged concentrating drum is rotatably connected in the secondary concentrating shell, a rotating motor for driving the concentrating drum to rotate is installed outside the secondary concentrating shell, and the concentrating drum is heated by a heating device. A strip dipping trough is provided in the secondary concentrating shell and on one side of the upper part of the concentrating drum, and the edge of the strip dipping trough is in sealing contact with the edge of the concentrating drum. The lower end of the drain pipe extends into the secondary concentrating shell and is located above the strip dipping trough. A material storage trough is provided in the secondary concentrating shell below the concentrating drum, a scraping bar cooperating with the concentrating drum is provided in the secondary concentrating shell below the strip dipping trough, a guide channel is provided in the secondary concentrating shell below the scraping bar and downward toward the material storage trough, and the upper end of the secondary concentrating shell is connected to a secondary exhaust pipe.

[0009] By adopting the above technical solution, after progesterone is concentrated, the progesterone solution is first added to the concentration tank through the feeding pipe. The progesterone solution is continuously heated and concentrated by the hot water in the heating chamber. During the process, the driving motor drives the stirrer to continuously stir the solution. Since the boiling point of alcohol solvents is relatively low, and the melting point of progesterone is higher than the boiling point of alcohol solvents, when the progesterone solution is heated to the boiling temperature of the alcohol solvent in the concentration tank and the progesterone solution reaches an appropriate concentration and no crystals are precipitated, the solenoid valve is opened to allow the progesterone solution to flow from the discharge pipe into the strip-shaped dipping tank. The rotary motor drives the concentration drum to rotate continuously, and the progesterone solution on the strip-shaped dipping tank is continuously adsorbed through the outer wall of the concentration drum. The progesterone solution has a larger surface area on the surface of the concentration drum. Due to the high temperature of the concentration drum, the alcohol solvent on the surface of the concentration drum is quickly evaporated, causing the progesterone to precipitate quickly on the surface. After the precipitated progesterone rotates to the scraper position, the scraper scrapes the progesterone and drops it onto the guide channel, and then slides through the guide channel into the storage tank.

[0010] The present invention is further configured such that a first condensation cylinder is provided outside the concentration tank, the first condensation cylinder is connected to a first water outlet pipe and a first water inlet pipe which are distributed up and down, a first spiral condensation tube is provided in the first condensation cylinder, the upper end of the first spiral condensation tube is connected to the free end of the first-level exhaust pipe, and the lower end of the first spiral condensation tube is provided with a first recovery pipe extending downward from the first condensation cylinder.

[0011] The present invention is further configured such that a second condensing cylinder is provided outside the secondary concentrating shell, the second condensing cylinder is connected to a second water outlet pipe and a second water inlet pipe which are distributed up and down, a second spiral condensing tube is provided in the second condensing cylinder, the upper end of the second spiral condensing tube is connected to the free end of the secondary exhaust pipe, and the lower end of the second spiral condensing tube is provided with a second recovery pipe extending downward from the second condensing tube.

[0012] The present invention is further configured such that the secondary concentrating shell is provided with a temperature regulating water tank at one end of the concentrating drum, an electric heating tube is provided in the temperature regulating water tank, one end of the concentrating drum extends into the temperature regulating water tank, the end of the concentrating drum extending into the temperature regulating water tank is open and is sealed and rotatably connected thereto, the inner wall of the concentrating drum is provided with a plurality of circumferentially distributed spiral turbulent blades, the temperature regulating water tank is connected to a return pipe extending into the concentrating drum, the temperature regulating water tank is provided with a forward flow channel communicating with one side of the heating chamber upwardly, the return pipe extends out of the end of the temperature regulating water tank outside the concentrating drum, and a countercurrent water channel communicating with the heating chamber is provided.

[0013] By adopting the above technical solution, after adding a sufficient amount of water to the temperature regulating water tank, the water is heated by the electric heating tube. During the process, the rotating motor drives the concentration drum to rotate. During the rotation of the concentration drum, the spiral turbulence blades on the inner wall of the concentration drum drive the water to form an inward-flowing vortex, and the vortex pushes the water to continuously enter the return pipe, and then flows along the return pipe and the countercurrent water channel into the heating chamber. The water in the heating chamber then flows back to the temperature regulating water tank and the concentration drum along the positive flow channel under the suction of the vortex, so that the internal water is evenly heated to 90℃-95℃.

[0014] The present invention is further configured such that the inner wall of the return pipe is provided with a plurality of circumferentially distributed spiral guide blades, and the spiral direction of the spiral guide blades is opposite to the spiral direction of the spiral spoiler blades.

[0015] The present invention is further configured such that the temperature regulating water tank is externally connected to a water supply pipe, and a valve is provided on the water supply pipe.

[0016] The present invention is further configured such that a discharge channel connected to the bottom of the storage trough is provided outwardly at the lower part of the secondary concentrating shell, a discharge port is provided on one side of the free end of the discharge channel, a spiral feed rod extending into the storage trough is rotatably connected to the discharge channel, and a feed motor for driving the spiral feed rod to rotate is installed at the free end of the discharge channel.

[0017] The present invention is further configured such that a concentration sensor for detecting the concentration of the solution inside the detector is provided at the upper end of the concentration tank.

[0018] The present invention is further configured such that valves are provided on the feeding pipe, the first-level exhaust pipe and the spare pipe.

[0019] The present invention is further configured such that the lower end of the concentration tank is tapered.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] First, when concentrating progesterone, the present invention first uses a concentrating tank to perform primary heating and concentration on the brass body. After the concentration reaches a certain level, the progesterone solution is transferred to a continuously rotating concentrating drum for secondary concentration. The rotating concentrating drum continuously adsorbs the progesterone solution, increasing the surface area of the progesterone solution, making it easier for solvent molecules to overcome the attraction between molecules in the liquid and become gaseous molecules. The solvent evaporates and gasifies quickly, causing the progesterone to be quickly concentrated and precipitated, thereby effectively improving the concentration efficiency of the progesterone.

[0022] Secondly, during the concentration process, the present invention can cause the heated water to circulate continuously between the heating chamber and the concentrating drum through the rotation of the concentrating drum, so that the water can be heated quickly and evenly, and the temperatures of the heating chamber and the concentrating drum can be controlled simultaneously. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0024] Figure 2 It is a partial cross-sectional view used to show the internal structure of the concentration tank;

[0025] Figure 3 It is a partial cross-sectional view used to show the internal structure of the secondary concentrating shell;

[0026] Figure 4 It is a cross-sectional view used to show the internal structure of the secondary concentrating shell;

[0027] Figure 5 Used to show the internal structure of the temperature regulating water tank;

[0028] Figure 6 It is a partial cross-sectional view used to show the internal structure of the concentration drum;

[0029] Figure 7 It is a partial cross-sectional view for showing the internal structure of the first condensing cylinder;

[0030] Figure 8 It is a partial cross-sectional view used to show the internal structure of the second condensing cylinder.

[0031] Among them, 1. Concentration tank; 2. Feeding pipe; 3. First-level exhaust pipe; 4. Spare pipe; 5. Valve; 6. Concentration sensor; 7. Drive motor; 8. Stirring shaft; 9. Stirrer; 10. Heating chamber; 11. Drain pipe; 12. Solenoid valve; 13. First condensing cylinder; 14. First water outlet pipe; 15. First water inlet pipe; 16. First spiral condensing tube; 17. First recovery pipe; 18. Second-level concentration shell; 19. Concentration drum; 20. Rotating motor; 21. Strip dipping tank; 22. Storage tank; 2 3. Scraper; 24. Guide channel; 25. Discharge channel; 26. Discharge port; 27. Spiral feed rod; 28. Feed motor; 29. Secondary exhaust pipe; 30. Second condenser; 31. Second water outlet pipe; 32. Second water inlet pipe; 33. Second spiral condenser; 34. Second recovery pipe; 35. Temperature regulating water tank; 36. Water supply pipe; 37. Electric heating pipe; 38. Spiral spoiler blade; 39. Return pipe; 40. Spiral guide blade; 41. Forward water channel; 42. Countercurrent water channel. DETAILED DESCRIPTION

[0032] The following is a detailed description of a progesterone raw material concentration system according to the present invention, with reference to the accompanying drawings and specific embodiments. The advantages and features of the present invention will become more apparent from the following description. It should be noted that the drawings are greatly simplified and not to exact scale, and are intended solely to facilitate and clearly illustrate the embodiments of the present invention. Identical or similar reference numerals in the drawings represent identical or similar components.

[0033] Example, see Figure 1-8 A concentrating system for producing progesterone raw materials includes a concentrating tank 1 with a tapered lower end. The upper end of the tank is connected to a feed pipe 2, a primary exhaust pipe 3, and a backup pipe 4. Each of the feed pipe 2, primary exhaust pipe 3, and backup pipe 4 is provided with a valve 5. A concentration sensor 6 for detecting the concentration of the solution within the tank is provided at the upper end of the tank 1. A drive motor 7 is mounted on the upper end of the tank 1. The power output shaft of the drive motor 7 is connected to a stirring shaft 8 extending into the tank 1. Multiple stirrers 9 are mounted on the stirring shaft 8. A heating chamber 10 is provided on the outer shell of the tank 1. A drain pipe 11 is connected to the lower end of the tank 1. A solenoid valve 12 is provided on the drain pipe 11.

[0034] A vertically arranged first condensing cylinder 13 is provided outside the concentration tank 1. The first condensing cylinder 13 is connected to a first water outlet pipe 14 and a first water inlet pipe 15 which are distributed up and down. Water enters through the first water outlet pipe 14 and exits from the first water inlet pipe 15. A first spiral condensing tube 16 is provided in the first condensing cylinder 13. The upper end of the first spiral condensing tube 16 is connected to the free end of the first-level exhaust pipe 3. The lower end of the first spiral condensing tube 16 is downwardly provided with a first recovery pipe 17 extending out of the first condensing cylinder 13. The boiling point of the alcohol organic solvent is relatively low. After being heated and evaporated, its vapor enters the first spiral condensing tube 16 and is condensed and recovered.

[0035] The secondary concentration shell 18 further includes a secondary concentration shell 18, in which a horizontally arranged concentration drum 19 is rotatably connected. A rotary motor 20 for driving the concentration drum 19 to rotate is installed outside the secondary concentration shell 18. The power output shaft of the rotary motor 20 is connected to one end of the concentration drum 19. A strip-shaped dipping liquid groove 21 is provided on one side of the upper part of the secondary concentration shell 18 and the upper part of the concentration drum 19. The edge of the strip-shaped dipping liquid groove 21 is in sealed contact with the edge of the concentration drum 19 to prevent the solution from flowing away between the strip-shaped dipping liquid groove 21 and the concentration drum 19. The drain pipe 11 is provided with a plurality of channels. The lower end of the secondary concentration shell 18 extends into the secondary concentration shell 18 and is located above the strip dipping liquid groove 21. A storage groove 22 is provided below the concentration drum 19 in the secondary concentration shell 18. A scraping bar 23 that cooperates with the concentration drum 19 is provided below the strip dipping liquid groove 21 in the secondary concentration shell 18. A guide channel 24 is provided below the scraping bar 23 and downward toward the storage groove 22 in the secondary concentration shell 18. After progesterone is precipitated on the surface of the concentration drum 19, it is hung on the guide channel 24 through the scraping bar 23 and falls into the storage groove 22 along the guide channel 24. A discharge channel 25 connected to the bottom of the storage trough 22 is provided outwardly at the lower part of the secondary concentrating shell 18. A discharge port 26 is provided on one side of the free end of the discharge channel 25. A spiral feed rod 27 extending into the storage trough 22 is rotatably connected to the discharge channel 25. A feed motor 28 for driving the spiral feed rod 27 to rotate is installed at the free end of the discharge channel 25.

[0036] The upper end of the secondary concentrating shell 18 is connected to a secondary exhaust pipe 29, and a vertically arranged second condensing cylinder 30 is provided outside the secondary concentrating shell 18. The second condensing cylinder 30 is connected to a second water outlet pipe 31 and a second water inlet pipe 32 distributed up and down. Water enters through the second water outlet pipe 31 and is discharged from the second water inlet pipe 32. A second spiral condensing tube 33 is provided in the second condensing cylinder 30. The upper end of the second spiral condensing tube 33 is connected to the free end of the secondary exhaust pipe 29, and the lower end of the second spiral condensing tube 33 is downwardly provided with a second recovery pipe 34 extending out of the second condensing cylinder 30. The steam evaporated from the secondary concentrating shell 18 enters the second spiral condensing tube 33 and is condensed and recovered.

[0037] The secondary concentration shell 18 is provided with a temperature regulating water tank 35 at one end of the concentration drum 19. The temperature regulating water tank 35 is connected to a water supply pipe 36, which is provided with a valve 5. A plurality of electric heating pipes 37 are provided in the temperature regulating water tank 35. One end of the concentration drum 19 extends into the temperature regulating water tank 35. The end of the concentration drum 19 extending into the temperature regulating water tank 35 is open and is sealed and rotatably connected thereto. The inner wall of the concentration drum 19 is provided with a plurality of spiral flow-turbulating blades 38 distributed in a circumferential manner. When the concentration drum 19 rotates, the spiral flow-turbulating blades 38 can disturb and generate vortexes flowing toward one end. The temperature regulating water tank 35 is connected to a return pipe 39 extending into the concentration drum 19. The inner wall of the return pipe 39 is provided with a plurality of spiral guide blades 40 distributed in a circumferential manner. The spiral direction of the spiral guide blades 40 is consistent with the spiral flow-turbulating blades 40. The spiral directions of the blades 38 are opposite, so that under the impetus of the vortex, the water flow can enter or be discharged from the return pipe 39. The temperature regulating water tank 35 is upwardly provided with a positive flow water channel 41 connected to one side of the heating chamber 10. The return pipe 39 extends out of the end outside the concentrating drum 19. The temperature regulating water tank 35 is provided with a countercurrent water channel 42 connected to the heating chamber 10, so that when the concentrating drum 19 rotates, the water flow can pass through the positive flow water channel 41 and the countercurrent water channel 42, thereby realizing the circulation of water in the heating chamber 10 and the water in the concentrating drum 19, ensuring uniform water temperature.

[0038] Working principle: After progesterone is concentrated, sufficient water is first added to the temperature regulating water tank 35, and the water is heated by the electric heating tube 37. During the process, the rotary motor 20 drives the concentration drum 19 to rotate. During the rotation of the concentration drum 19, the spiral turbulent blades 38 on the inner wall of the concentration drum 19 drive the water to form an inward vortex, and the vortex pushes the water to continuously enter the return pipe 39. The water flows along the return pipe 39 and the countercurrent water channel 42 into the heating chamber 10. The water in the heating chamber 10 then flows back to the temperature regulating water tank 35 and the concentration drum 19 along the positive flow channel 41 under the suction of the vortex, so that the water inside is evenly heated to 90°C-95°C.

[0039] Subsequently, the progesterone solution is added to the concentration tank 1 through the feeding pipe 2, and the progesterone solution is continuously heated and concentrated by the hot water in the heating chamber 10. During the process, the driving motor 7 drives the stirrer 9 to continuously stir the solution. Since the boiling point of alcohol solvents is relatively low, and the melting point of progesterone is higher than the boiling point of alcohol solvents, the alcohol solvent is heated rapidly and evaporated by heating, so that the concentration of the progesterone solution is continuously increased. The evaporated alcohol solvent in the process is discharged through the first exhaust pipe 3 into the first spiral condenser 16. Under the action of the circulating cold water in the first condenser cylinder 13, it is quickly condensed into liquid and finally flows out from the first recovery pipe 17 for recovery;

[0040] When the progesterone solution is heated to the boiling temperature of the alcohol solvent in the concentration tank 1, and the progesterone solution reaches an appropriate concentration and no crystals are precipitated, the solenoid valve 12 is opened to allow the progesterone solution to flow from the discharge pipe 11 into the strip-shaped dipping tank 21. The rotary motor 20 drives the concentration drum 19 to rotate continuously, and the outer wall of the concentration drum 19 continuously absorbs the progesterone solution on the strip-shaped dipping tank 21. The progesterone solution obtains a larger surface area on the surface of the concentration drum 19, and due to the high temperature of the concentration drum 19, the progesterone solution on the strip-shaped dipping tank 21 is heated. The alcohol solvent on the surface of the concentration drum 19 evaporates quickly, causing progesterone to precipitate quickly on the surface. The alcohol vapor generated in the process is discharged through the secondary exhaust pipe 29 and enters the second spiral condenser 33 for condensation and recovery. After the precipitated progesterone rotates to the position of the scraper 23, the scraper 23 scrapes the progesterone and drops it onto the guide channel 24. Then, it slides through the guide channel 24 into the storage tank 22. When the concentration is completed, the feeding motor 28 drives the spiral feeding rod 27 to discharge the progesterone in the storage tank 22.

[0041] It should also be noted that all references to "disposed" and similar descriptors in this application (especially in this specification) express that two structures have or exist in a connection relationship. However, the specific means by which the two structures are connected are not particularly limited, and are generally conventional connection means. In other words, such means should be understood as existing in the art and do not require further elaboration. For example, "n is disposed on m" simply expresses that structure n is present on structure m, while the two are specifically connected by welding, riveting, adhesive bonding, or integral molding, all of which are within the scope of protection of this application. Another example is "y is rotatably disposed on x" simply expresses that y and x are rotatable relative to each other, while whether the two are connected by a bearing, y directly passes through x and is rotatably connected to x, or other feasible methods are all within the scope of protection of this application.

[0042] The above description is only a description of the preferred embodiments of the present invention and does not limit the scope of the present invention. Any changes and modifications made by ordinary technicians in the field of the present invention based on the above disclosure shall fall within the scope of protection of the claims.

Claims

1. A concentration system for producing progesterone raw materials, comprising a concentration tank (1), wherein the upper end of the concentration tank (1) is connected to a feeding pipe (2), a primary exhaust pipe (3) and a spare pipe (4), characterized in that: The upper end of the concentration tank (1) is equipped with a driving motor (7), the power output shaft of the driving motor (7) is connected to a stirring shaft (8) extending into the concentration tank (1), and a stirrer (9) is installed on the stirring shaft (8). The concentration tank (1) is provided with a heating chamber (10) on its outer cover, and the lower end of the concentration tank (1) is connected to a drain pipe (11), and a solenoid valve (12) is provided on the drain pipe (11); The secondary concentration shell (18) further comprises a secondary concentration shell (18), wherein a horizontally arranged concentration drum (19) is rotatably connected therein, and a rotary motor (20) is mounted outside the secondary concentration shell (18) for driving the concentration drum (19) to rotate. The concentration drum (19) is heated by a heating device. A strip-shaped dipping liquid groove (21) is provided on one side of the secondary concentration shell (18) and the upper part of the concentration drum (19). The edge of the strip-shaped dipping liquid groove (21) is in sealing contact with the edge of the concentration drum (19). The lower end of the discharge pipe (11) extends into the secondary concentration shell (18). The secondary concentration shell (18) is located above the strip-shaped dipping liquid trough (21), a material storage trough (22) is provided in the secondary concentration shell (18) below the concentration roller (19), a scraper (23) is provided in the secondary concentration shell (18) below the strip-shaped dipping liquid trough (21) to match the concentration roller (19), a guide channel (24) is provided in the secondary concentration shell (18) below the scraper (23) and downwardly toward the material storage trough (22), and the upper end of the secondary concentration shell (18) is connected to a secondary exhaust pipe (29).

2. A concentration system for producing progesterone raw materials according to claim 1, characterized in that: A first condensation tube (13) is provided outside the concentration tank (1), and the first condensation tube (13) is connected to a first water outlet pipe (14) and a first water inlet pipe (15) which are distributed in an upper and lower manner. A first spiral condensation tube (16) is provided in the first condensation tube (13), and the upper end of the first spiral condensation tube (16) is connected to the free end of the first-level exhaust pipe (3), and the lower end of the first spiral condensation tube (16) is provided with a first recovery pipe (17) extending downward from the first condensation tube (13).

3. The progesterone raw material production concentration system according to claim 1, characterized in that: A second condensation cylinder (30) is provided outside the secondary concentration shell (18), and the second condensation cylinder (30) is connected to a second water outlet pipe (31) and a second water inlet pipe (32) distributed in an upper and lower manner. A second spiral condensation tube (33) is provided in the second condensation cylinder (30), and the upper end of the second spiral condensation tube (33) is connected to the free end of the secondary exhaust pipe (29), and the lower end of the second spiral condensation tube (33) is provided with a second recovery pipe (34) extending downward from the second condensation cylinder (30).

4. The progesterone raw material production concentration system according to claim 1, characterized in that: The secondary concentration shell (18) is provided with a temperature regulating water tank (35) at one end of the concentration drum (19), and an electric heating pipe (37) is provided in the temperature regulating water tank (35). One end of the concentration drum (19) extends into the temperature regulating water tank (35), and the end of the concentration drum (19) extending into the temperature regulating water tank (35) is open and is sealed and rotatably connected to the temperature regulating water tank (35). The inner wall of the concentration drum (19) is provided with a plurality of spiral turbulent blades (38) distributed in a circumferential manner. The temperature regulating water tank (35) is connected to a return pipe (39) extending into the concentration drum (19). The temperature regulating water tank (35) is provided with a forward flow channel (41) communicating with one side of the heating chamber (10) upwardly. The return pipe (39) extends out of the temperature regulating water tank (35) at one end outside the concentration drum (19) and is provided with a reverse flow channel (42) communicating with the heating chamber (10).

5. The progesterone raw material production concentration system according to claim 4, characterized in that: The inner wall of the return pipe (39) is provided with a plurality of circumferentially distributed spiral guide blades (40), and the spiral direction of the spiral guide blades (40) is opposite to the spiral direction of the spiral spoiler blades (38).

6. The progesterone raw material production concentration system according to claim 4, characterized in that: The temperature regulating water tank (35) is externally connected to a water supply pipe (36), and a valve (5) is provided on the water supply pipe (36).

7. The progesterone raw material production concentration system according to claim 1, characterized in that: A discharge channel (25) communicating with the bottom of the storage tank (22) is provided outwardly at the lower portion of the secondary concentration shell (18), a discharge port (26) is provided on one side of the free end of the discharge channel (25), a spiral feed rod (27) extending into the storage tank (22) is rotatably connected in the discharge channel (25), and a feed motor (28) for driving the spiral feed rod (27) to rotate is installed at the free end of the discharge channel (25).

8. The concentration system for producing progesterone raw materials according to claim 1, characterized in that: A concentration sensor (6) for detecting the concentration of the solution inside the detector is provided at the upper end of the concentration tank (1).

9. The progesterone raw material production concentration system according to claim 1, characterized in that: The feeding pipe (2), the first-level exhaust pipe (3) and the spare pipe (4) are all provided with valves (5).

10. The progesterone raw material production concentration system according to claim 1, characterized in that: The lower end of the concentration tank (1) is tapered.

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