Tumor experiment medicine preparation device
By designing the drug configuration components, cutting and release components and anti-spill communication components of the tumor experimental drug configuration device, the problem of drug inhalation in the prior art is solved, and the precise configuration and direct delivery of tumor drugs are achieved.
Patent Information
- Application Number
- CN202510777725.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-11
- Publication Date
- 2025-08-15
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
When the existing inhaler cuts and crushes the capsule, some of the powder remains in the capsule or spills out, resulting in a deviation in the amount of anti-tumor drugs, affecting the precise configuration of tumor experimental drugs.
A tumor experimental drug configuration device is designed, including drug configuration components, cutting and release components, anti-spill communication components and intake control components. Through the synergy of these components, the quantitative cutting and separation of drugs can be ensured, spillover avoided, and precise configuration is achieved.
The precise configuration of anti-tumor drugs is achieved, ensuring that the drug is delivered directly to the tumor site in the lungs, reducing the deviation of drug inhalation and improving the accuracy of the experiment.
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Figure CN120478786A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the field of biomedical technology, in particular to a tumor experiment drug configuration device. Background Art
[0002] In biomedicine, in some experiments targeting lung tumors, anti-tumor drugs need to be delivered directly to the human lung tumor site. Inhalers can make drugs into dry powder form, so that the drugs can reach the lung tumor tissue through the respiratory tract and achieve local administration. This method helps to increase the drug concentration in the tumor site while reducing the side effects of systemic administration. For example, when developing new drugs to treat lung cancer, inhalers may be used to deliver drugs to lung tumors to observe the drug's inhibitory effect on tumors and its metabolism in the lungs.
[0003] When using the inhaler, multiple groups of capsules containing a fixed amount of powdered anti-tumor drugs are placed inside the inhaler and cut and crushed when needed to achieve the quantitative configuration effect of the powdered anti-tumor drugs. However, after the capsules are cut and crushed, some powder remains in the capsules and some powder overflows when punctured, resulting in deviations in the actual inhaled amount of anti-tumor drugs, affecting the precise configuration and use of anti-tumor experimental drugs. To this end, we propose a anti-tumor experimental drug configuration device. Summary of the Invention
[0004] The purpose of the present invention is to provide a tumor experimental drug preparation device to solve the problems raised in the above background technology.
[0005] To achieve the above objectives, the present invention provides the following technical solutions: a tumor experimental drug preparation device, comprising an inhaler for preparing and administering a dry powdered tumor drug, the inhaler comprising a housing, a partition fixed to the interior of the housing, and the interior of the housing divided by the partition into a preparation chamber and a processing chamber, the preparation chamber being located above the processing chamber, a suction tube fixed to the housing, one end of the suction tube being fixedly mounted to the bottom of the partition, the other end of the suction tube being located outside the housing and having a plug threadedly mounted thereon, a cover plate threadedly connected to the top of the housing for sealing and covering the preparation chamber, and further comprising:
[0006] A drug dispensing assembly is disposed inside the dispensing chamber for quantitatively dispensing the drug. The drug dispensing assembly is provided in a plurality of groups in a circular array inside the dispensing chamber. An adjustment assembly is provided inside the dispensing chamber for adjusting the position of each group of drug dispensing assembly.
[0007] A cutting and releasing component is disposed inside the dispensing cavity and is used to cut and release the medicine stored on the medicine dispensing component;
[0008] An anti-overflow communication component is provided on the partition plate for communicating between the suction tube and the drug dispensing component during drug release;
[0009] The air intake control component is arranged between the medicine dispensing component and the shell and is used for air intake control during subsequent inhalation after medicine dispensing.
[0010] Preferably, the drug dispensing assembly includes a placement cylinder, on which a capsule is placed, the interior of the capsule being filled with a tumor experimental drug, two sets of connecting belts being fixed to the outside of the capsule, two sets of positioning splints for positioning the connecting belts being slidably connected to the placement cylinder, and a pushing assembly for pushing the two sets of positioning splints being provided on the outside of the placement cylinder;
[0011] By adopting the above technical solution, the two groups of connecting belts on the capsule are respectively clamped into the two groups of positioning clamps of the placement cylinder to position the placed capsule.
[0012] Preferably, the cutting and releasing assembly includes a slot formed on the placement cylinder, a mounting frame is provided inside the configuration cavity, a cutter for cutting the capsule through the slot is fixed on the mounting frame, a fixing frame is fixed on the upper end of the partition, and a cylinder for pushing the mounting frame is installed on the fixing frame;
[0013] By adopting the above technical solution, the antitumor drug inside the capsule is released. During the release process, the released antitumor drug falls into the interior of the suction tube through the connecting tube due to gravity.
[0014] Preferably, the overflow prevention connecting assembly includes a connecting pipe for being sleeved and connected to the outer side of the placement cylinder, the lower end of the connecting pipe is communicated with the interior of the suction pipe, the upper end of the connecting pipe is fixed with a push ring, a plurality of groups of T-shaped rods are fixed on the push ring, the T-shaped rods are slidably connected to the partition, and the partition is provided with a lifting assembly for lifting the connecting pipe;
[0015] By adopting the above technical solution, there is no gap between the connecting tube and the placement tube in the vertical direction, which avoids the existence of the gap causing the anti-tumor drug released after cutting inside the placement tube to partially overflow when falling into the suction tube.
[0016] Preferably, the lifting assembly includes a circular hole formed on the partition plate, a threaded sleeve is rotatably connected to the circular hole, the outer side of the connecting pipe is threadedly engaged with the inner side of the threaded sleeve, a first gear ring is fixed to the outer side of the threaded sleeve, and a rack for engaging and transmitting with the first gear ring is fixed to the mounting bracket;
[0017] By adopting the above technical solution, the connecting pipe is driven to move up and down under force.
[0018] Preferably, the pushing assembly includes a lifting ring for resisting and transmitting with the push ring, the lifting ring is in a sleeve state and slidably connected to the outer side of the placement cylinder by means of a slide groove and a slider, a connecting rod is provided between the lifting ring and the positioning clamping plate, and the two ends of the connecting rod are rotatably connected to the positioning clamping plate and the lifting ring respectively through a pin shaft;
[0019] By adopting the above technical solution, the two groups of positioning clamps on the placement tube are pulled and forced to move toward the outside of the placement tube.
[0020] Preferably, the air intake control assembly includes an air intake pipe connected to and fixed to the outside of the placement cylinder, the housing is provided with a mounting hole, a sliding pipe is slidably connected to the mounting hole, the sliding pipe is provided with multiple groups of air intake holes for air intake, one end of the sliding pipe is located inside the configuration cavity and is provided with a transmission assembly for transmission with the air intake pipe;
[0021] By adopting the above technical solution, the ventilation and blocking of the air intake pipe are controlled.
[0022] Preferably, the transmission assembly includes a conical sleeve fixed to the end of the sliding tube, the outer side of the conical sleeve is provided with a conical surface for abutting against the end of the intake pipe for transmission, the outer side of the sliding tube is provided with a spring, and the two ends of the spring are respectively abutted against the inner wall of the housing and the end of the conical sleeve;
[0023] By adopting the above technical solution, the sliding tube is pushed to move toward the outside of the shell.
[0024] Preferably, the adjustment assembly includes a drive ring rotatably connected to the interior of the configuration cavity, the drive ring is fixedly connected to the placement cylinder via a connecting plate, and the housing is provided with a rotating assembly for rotating the drive ring;
[0025] By adopting the above technical solution, the use position of the placement cylinder is adjusted.
[0026] Preferably, the rotating assembly includes a second gear ring fixed to the lower end of the driving ring, a mounting shaft is rotatably connected to the housing, a gear is fixed to one end of the mounting shaft, the gear and the second gear ring are meshed with each other, and a driving motor for driving the mounting shaft is installed on the outer side of the housing;
[0027] By adopting the above technical solution, the driving ring is driven to move.
[0028] Compared with the prior art, the present invention has the following beneficial effects:
[0029] The present invention is aimed at lung tumor experiments. Through the configuration of the inhaler, a quantitative amount of anti-tumor drugs is delivered directly to the lung tumor site of the human body. During use of the inhaler, the cutting release component, the anti-overflow connecting component and the air intake control component cooperate with each other to fully separate the cut tumor experimental drugs and inhibit partial overflow, thereby avoiding deviations in the actual inhaled amount of anti-tumor drugs and ensuring the accurate configuration and use of the tumor experimental drugs. BRIEF DESCRIPTION OF THE DRAWINGS
[0030] Figure 1 It is a schematic diagram of the overall appearance structure of the present invention;
[0031] Figure 2 This is a schematic diagram of the internal structure of the configuration chamber of the present invention;
[0032] Figure 3 Schematic diagram of the internal structure of the housing of the present invention;
[0033] Figure 4 This is a schematic diagram of the positional relationship between the placement cylinder and the drive ring of the present invention;
[0034] Figure 5 This is a schematic structural diagram of the cutting release assembly of the present invention;
[0035] Figure 6 This is a schematic diagram of the air intake control assembly of the present invention when in use;
[0036] Figure 7 This is a schematic diagram of the air intake control assembly of the present invention after use;
[0037] Figure 8 This is a schematic diagram of the structure of the push assembly of the present invention;
[0038] Figure 9 This is a schematic structural diagram of the anti-overflow connection component of the present invention;
[0039] Figure 10 It is a schematic structural diagram of the lifting assembly of the present invention;
[0040] Figure 11 Schematic diagram of the capsule structure of the present invention;
[0041] Figure 12 Schematic diagram of different states during the capsule cutting process of the present invention.
[0042] In the figure: 101-shell; 1011-processing chamber; 1012-configuration chamber; 102-partition plate; 103-intake pipe; 104-plug; 105-cover plate; 201-placement cylinder; 202-capsule; 203-connecting belt; 204-positioning clamp; 301-drive ring; 302-connecting plate; 401-second gear ring; 402-mounting shaft; 403-gear; 404-drive motor; 501-slot; 50 2-mounting frame; 503-cutter; 504-fixed frame; 505-cylinder; 601-lifting ring; 602-connecting rod; 701-connecting pipe; 702-push ring; 703-T-bar; 801-threaded sleeve; 802-first gear ring; 803-rack; 901-inlet pipe; 902-mounting hole; 903-sliding tube; 904-inlet hole; 1001-conical sleeve; 1002-conical surface; 1003-spring. DETAILED DESCRIPTION
[0043] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.
[0044] Example 1
[0045] See also Figures 1-12 The device for preparing a drug for a tumor experiment shown in the figure includes an inhaler for preparing and administering a dry powdered tumor drug. The inhaler includes a housing 101. A partition 102 is fixed to the interior of the housing 101. The interior of the housing 101 is divided by the partition 102 to form a preparation chamber 1012 and a processing chamber 1011. The preparation chamber 1012 is located above the processing chamber 1011. A suction pipe 103 is fixed to the housing 101. One end of the suction pipe 103 is fixed to the bottom of the partition 102. The other end of the suction pipe 103 is located outside the housing 101 and is threadedly mounted with a plug 104. A cover plate 105 for sealing the preparation chamber 1012 is threadedly connected to the top of the housing 101. The device also includes:
[0046] The drug dispensing assembly is disposed inside the dispensing chamber 1012 for quantitative dispensing of the drug. Multiple groups of drug dispensing assemblies are disposed in a circular array inside the dispensing chamber 1012. An adjustment assembly is disposed inside the dispensing chamber 1012 for adjusting the position of each group of drug dispensing assemblies.
[0047] A cutting and releasing component is disposed inside the dispensing cavity 1012 and is used to cut and release the medicine stored on the medicine dispensing component;
[0048] An anti-overflow communication component is provided on the partition 102 for communicating between the suction tube 103 and the drug dispensing component during drug release;
[0049] An air intake control component is provided between the drug dispensing component and the housing 101 and is used for air intake control during subsequent inhalation after drug dispensing;
[0050] It should be noted here that in experiments on lung tumors, a fixed amount of anti-tumor drugs is delivered directly to the human lung tumor site through the configuration of the inhaler. During the use of the inhaler, the cutting release component, the anti-overflow connection component and the air intake control component cooperate with each other to fully separate the cut tumor experimental drugs and inhibit partial overflow, thereby avoiding deviations in the actual inhaled amount of anti-tumor drugs and ensuring the accurate configuration and use of tumor experimental drugs.
[0051] Preferably, the drug dispensing assembly includes a placement cylinder 201, on which a capsule 202 is placed. The interior of the capsule 202 is filled with a tumor experimental drug. Two sets of connecting belts 203 are fixed to the outside of the capsule 202. Two sets of positioning splints 204 for positioning the connecting belts 203 are slidably connected to the placement cylinder 201. A pushing assembly for pushing the two sets of positioning splints 204 is provided on the outside of the placement cylinder 201.
[0052] It should be noted that capsules 202 loaded with a fixed amount of dry powdered tumor drug are sequentially placed into the placement tube 201 of the configuration chamber 1012. During the placement process, the two sets of connecting bands 203 on the capsules 202 are respectively engaged with the two sets of positioning clamps 204 of the placement tube 201 to position the placed capsules 202.
[0053] It should be noted here that the filling of the quantitative dry powder tumor drug inside the capsule 202 can be performed using an automatic capsule filling machine. The filling operation of the automatic capsule filling machine and the fixation of the connecting belt 203 on the outside of the capsule 202 are conventional technical means in this application, and its working principle and operation method are not described in detail here.
[0054] Preferably, the cutting and releasing assembly includes a slot 501 formed on the placement cylinder 201, a mounting frame 502 disposed within the configuration chamber 1012, a cutter 503 fixed to the mounting frame 502 for cutting the capsule 202 through the slot 501, a fixing frame 504 fixed to the upper end of the partition 102, and a cylinder 505 mounted on the fixing frame 504 for pushing the mounting frame 502;
[0055] It should be noted that the mounting frame 502 is driven by the cylinder 505 to move toward the placement cylinder 201. During this movement, the cutter 503 on the mounting frame 502 passes through the slot 501 of the placement cylinder 201 and cuts the capsule 202 positioned therein, thereby releasing the anti-tumor drug in the capsule 202. During the release process, gravity causes the released anti-tumor drug to fall into the interior of the suction tube 103 through the connecting tube 701.
[0056] It is worth noting here that the cylinder 505 is a conventional driving component, and its working principle and operation method are considered as existing technology and will not be described in detail.
[0057] Preferably, the overflow prevention connecting assembly includes a connecting pipe 701 for being sleeved and connected to the outer side of the placement cylinder 201, the lower end of the connecting pipe 701 is communicated with the interior of the suction pipe 103, the upper end of the connecting pipe 701 is fixed with a push ring 702, and a plurality of groups of T-shaped rods 703 are fixed on the push ring 702. The T-shaped rods 703 are slidably connected to the partition 102, and the partition 102 is provided with a lifting assembly for raising and lowering the connecting pipe 701;
[0058] It should be noted here that: in the process of driving the mounting frame 502 to move and cut the capsule 202, the connecting tube 701 is sleeved on the outside of the placement tube 201 through transmission, and the sleeve connection effect is used to prevent there from being a gap between the connecting tube 701 and the placement tube 201 in the vertical direction, thereby avoiding the existence of the gap causing the anti-tumor drug released after the cutting inside the placement tube 201 to partially overflow when falling into the suction tube 103. After cutting, the connecting tube 701 is lowered through transmission to avoid the sleeve effect of the connecting tube 701 interfering with the position adjustment of the placement tube 201.
[0059] Preferably, the lifting assembly includes a circular hole formed on the partition 102, a threaded sleeve 801 being rotatably connected to the circular hole, the outer side of the connecting pipe 701 being threadedly engaged with the inner side of the threaded sleeve 801, a first gear ring 802 being fixed to the outer side of the threaded sleeve 801, and a rack 803 being fixed to the mounting frame 502 for meshing with the first gear ring 802;
[0060] It should be noted here that: in the process of driving the mounting frame 502 to move and cut the capsule 202, the rack 803 is driven to move synchronously. During the movement of the rack 803, the threaded sleeve 801 is rotated through the mutual engagement transmission between the rack 803 and the first gear ring 802. During the rotation of the threaded sleeve 801, the connecting tube 701 is driven to move upward under force through the mutual engagement transmission between the threaded sleeve 801 and the connecting tube 701.
[0061] Preferably, the pushing assembly includes a lifting ring 601 for resisting and transmitting against the push ring 702. The lifting ring 601 is sleeved and slidably connected to the outer side of the placement cylinder 201 by means of a slide groove and a slider. A connecting rod 602 is provided between the lifting ring 601 and the positioning clamping plate 204. The two ends of the connecting rod 602 are rotatably connected to the positioning clamping plate 204 and the lifting ring 601 respectively through a pin shaft.
[0062] It should be noted here that: during the upward movement of the connecting tube 701, the push ring 702 is offset against the lifting ring 601, pushing the lifting ring 601 to move upward under force. During the upward movement of the lifting ring 601, the two sets of positioning splints 204 on the placement tube 201 are pulled and forced to move toward the outside of the placement tube 201 through the connection transmission of the connecting rod 602. Because the two sets of connecting belts 203 of the capsule 202 are respectively clamped and installed on the two sets of positioning splints 204, the movement of the two sets of positioning splints 204 pulls the capsule 202 to both sides during the cutting process, thereby increasing the opening degree of the capsule 202 during the cutting process, and facilitating the full separation and falling of the anti-tumor drugs on the capsule 202.
[0063] Preferably, the air intake control assembly includes an air intake pipe 901 that is connected and fixed to the outside of the placement cylinder 201. The housing 101 is provided with a mounting hole 902. A sliding pipe 903 is slidably connected to the mounting hole 902. The sliding pipe 903 is provided with multiple groups of air intake holes 904 for air intake. One end of the sliding pipe 903 is located inside the configuration cavity 1012 and is provided with a transmission assembly for transmission with the air intake pipe 901.
[0064] It should be noted here that: through transmission, the placement cylinder 201 loaded with the capsule 202 is rotated to the top of the suction tube 103. During the rotation, each group of air inlet holes 904 is located on the outside of the shell 101, which is convenient for the inhalation operation during use. After inhalation, through transmission, each group of air inlet holes 904 is located inside the mounting hole 902. At this time, the sliding tube 903 is not connected to the outside of the shell 101, avoiding the capsule 202 placed on the placement cylinder 201 inside the configuration cavity 1012 from being in contact with the external air for a long time due to the communication between the sliding tube 903 and the outside of the shell 101, resulting in oxidation reaction changes.
[0065] Preferably, the transmission assembly includes a conical sleeve 1001 fixed to the end of the sliding tube 903. The outer side of the conical sleeve 1001 is provided with a conical surface 1002 for abutting against the end of the intake pipe 901 for transmission. The outer side of the sliding tube 903 is provided with a spring 1003. The two ends of the spring 1003 are respectively abutted against the inner wall of the housing 101 and the end of the conical sleeve 1001.
[0066] It should be noted here that: the placement cylinder 201 loaded with the capsule 202 is rotated to the top of the suction tube 103. During the rotation, the end of the air inlet pipe 901 on the placement cylinder 201 is abutted against the conical surface 1002 of the conical sleeve 1001 at the end of the sliding tube 903. During the abutment, the sliding tube 903 is pushed toward the outside of the shell 101. Through the movement of the sliding tube 903, each group of air inlet holes 904 is located on the outside of the shell 101. During the movement, the spring 1003 is deformed by force to generate elastic force. The elastic force of the spring 1003 facilitates the subsequent reset movement of the sliding tube 903.
[0067] Example 2
[0068] See also Figure 2 and Figure 3 This embodiment further illustrates the first embodiment. The adjustment assembly shown in the figure includes a drive ring 301 rotatably connected to the interior of the configuration cavity 1012. The drive ring 301 is fixedly connected to the placement cylinder 201 via a connecting plate 302. The housing 101 is provided with a rotating assembly for rotating the drive ring 301.
[0069] It should be noted here that: the driving ring 301 is rotated by rotating the assembly. During the rotation of the driving ring 301, the placement tube 201 is driven to move through the connection function of the connecting plate 302, and the use position of the placement tube 201 is adjusted.
[0070] Preferably, the rotating assembly includes a second gear ring 401 fixed to the lower end of the driving ring 301, a mounting shaft 402 is rotatably connected to the housing 101, a gear 403 is fixed to one end of the mounting shaft 402, the gear 403 and the second gear ring 401 are meshed with each other, and a driving motor 404 for driving the mounting shaft 402 is installed on the outside of the housing 101;
[0071] It should be noted that the mounting shaft 402 and the gear 403 at one end of the mounting shaft 402 are driven to rotate by the driving motor 404. During the rotation of the gear 403, the gear 403 and the second ring gear 401 are meshed with each other, thereby driving the driving ring 301 to move.
[0072] It is worth noting here that the driving motor 404 is a conventional rotating component, and its working principle and operation method are considered as prior art in this application and will not be described in detail here.
[0073] In this scheme: A tumor experimental drug preparation device includes the following steps:
[0074] In the experiment on lung tumor, the configuration function of the inhaler is used to deliver a fixed amount of anti-tumor drugs directly to the lung tumor site of the human body. During the use of the inhaler, the capsules 202 loaded with a fixed amount of dry powdered tumor drugs are sequentially placed inside the placement tube 201 of the configuration chamber 1012. During the placement process, the two sets of connecting belts 203 on the capsule 202 are respectively inserted into the two sets of positioning clamps 204 of the placement tube 201 to position the placed capsule 202. After the capsule 202 is placed, the configuration chamber 1012 is covered with a cover plate 105. After covering, the anti-tumor drugs need to be administered. During inhalation, the placement cylinder 201 loaded with the capsule 202 is rotated to the top of the inhalation tube 103 by the rotating assembly and the adjusting assembly. During the rotation process, the end of the air inlet pipe 901 on the placement cylinder 201 is abutted against the conical surface 1002 of the conical sleeve 1001 at the end of the sliding tube 903. During the abutment process, the sliding tube 903 is pushed toward the outside of the shell 101. The movement of the sliding tube 903 makes each group of air inlet holes 904 located outside the shell 101, and after the position of the placement cylinder 201 is rotated, one end of the air inlet pipe 901 remains abutted against the end of the conical sleeve 1001 (see FIG. Figure 6 At this time, the placement cylinder 201 at this position can communicate with the outside of the housing 101 through the air inlet pipe 901, the conical sleeve 1001, the sliding tube 903 and the air inlet holes 904;
[0075] After the placement cylinder 201 is adjusted to the specified position, the mounting frame 502 is driven by the cylinder 505 to move toward the placement cylinder 201. During the movement, the cutter 503 on the mounting frame 502 passes through the slot 501 of the placement cylinder 201 and cuts the capsule 202 positioned and placed inside, so that the anti-tumor drug inside the capsule 202 is released. During the release process, the released anti-tumor drug falls into the interior of the suction tube 103 through the connecting tube 701 by gravity. After cutting, the user can remove the plug 104 from the outer end of the suction tube 103 and inhale the anti-tumor drug released from the suction tube 103 into the lungs by inhalation, thereby achieving the quantitative configuration and inhalation operation of the anti-tumor drug. During the inhalation process, part of the external air passes through the air inlet 904, the sliding tube 903, the air inlet pipe 904, the air inlet pipe 903, and the air inlet pipe 903. 901, the placement tube 201, the connecting tube 701 and the inhalation tube 103 are inhaled into the lungs. During the process of air circulation inside the placement tube 201, the pressure generated during inhalation can fully separate the anti-tumor drugs on the cut capsule 202 from the capsule 202. After inhalation, the plug 104 is connected to the end of the inhalation tube 103, and the position of the placement tube 201 is adjusted by the rotating component and the adjusting component so that the placement tube 201 is no longer above the inhalation tube 103. In the process of adjusting the position of the placement tube 201, the air inlet pipe 901 is no longer against the tapered surface 1002 on the tapered sleeve 1001. At this time, the sliding tube 903 is reset under the elastic force of the spring 1003. Through the reset of the sliding tube 903, each group of air inlet holes 904 is located inside the mounting hole 902 (see Figure 7 In this state, the sliding tube 903 is not in communication with the outside of the housing 101, thereby preventing the capsule 202 placed on the placement tube 201 in the configuration chamber 1012 from being exposed to the outside air for a long time due to the communication between the sliding tube 903 and the outside of the housing 101, thereby preventing the capsule 202 from being oxidized and changing;
[0076] In the process of driving the mounting frame 502 to move and cut the capsule 202, the rack 803 is driven to move synchronously. During the movement of the rack 803, the rack 803 and the first gear ring 802 are meshed with each other to drive the threaded sleeve 801 to rotate. During the rotation of the threaded sleeve 801, the threaded sleeve 801 and the connecting tube 701 are meshed with each other to drive the connecting tube 701 to move upward. During the upward movement of the connecting tube 701, the connecting tube 701 is sleeved on the outside of the placement cylinder 201 (see FIG. 2 ). Figure 121 and 103, and the lifting ring 601 is pressed against the lifting ring 601, thereby pushing the lifting ring 601 upward. During the upward movement of the lifting ring 601, the two sets of positioning clamps 204 on the placement tube 201 are pulled toward the outside of the placement tube 201 through the connection transmission of the connecting rod 602. Because the two sets of connecting belts 203 of the capsule 202 are respectively fixed on the two sets of positioning clamps 204, the movement of the two sets of positioning clamps 204 pulls the capsule 202 to both sides during the cutting process, thereby increasing the opening degree of the capsule 202 during the cutting process, facilitating the full separation and falling of the anti-tumor drug on the capsule 202, and avoiding the deviation of the actual inhalation amount of the anti-tumor drug, thereby ensuring the accurate configuration and use of the tumor experimental drug.
[0077] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.
[0078] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.
Claims
1. A tumor experimental drug preparation device, comprising: An inhaler for dispensing and administering dry powdered tumor drugs, the inhaler comprising a shell (101), a partition (102) fixed inside the shell (101), and a dispensing chamber (1012) and a processing chamber (1011) formed inside the shell (101) by the partition (102), wherein the dispensing chamber (1012) is located above the processing chamber (1011), an inhalation tube (103) fixed on the shell (101), one end of the inhalation tube (103) being fixedly mounted on the bottom of the partition (102), the other end of the inhalation tube (103) being located outside the shell (101) and being threadedly mounted with a plug (104), and a cover plate (105) for sealing and covering the dispensing chamber (1012) being threadedly connected to the top of the shell (101); It is characterized by further comprising: A drug dispensing component is provided inside the dispensing cavity (1012) for quantitative dispensing of drugs, wherein a plurality of drug dispensing components are provided in a circular array inside the dispensing cavity (1012), and an adjusting component is provided inside the dispensing cavity (1012) for adjusting the position of each group of drug dispensing components; A cutting and releasing component is disposed inside the configuration cavity (1012) and is used for cutting and releasing the medicine stored on the medicine configuration component; An anti-overflow communication component is provided on the partition (102) and is used for communicating between the suction tube (103) and the drug dispensing component during the drug release process; The air intake control component is arranged between the medicine dispensing component and the housing (101) and is used for air intake control during subsequent inhalation after the medicine is dispensed.
2. The tumor experiment drug preparation device according to claim 1, characterized in that: The drug configuration component includes a placement tube (201), a capsule (202) is placed on the placement tube (201), the interior of the capsule (202) is filled with tumor experimental drugs, two groups of connecting belts (203) are fixed to the outside of the capsule (202), two groups of positioning splints (204) for positioning the connecting belts (203) are slidably connected to the placement tube (201), and a pushing component for pushing the two groups of positioning splints (204) is provided on the outside of the placement tube (201).
3. The tumor experiment drug preparation device according to claim 2, characterized in that: The cutting and releasing assembly comprises a slot (501) formed on the placement cylinder (201); a mounting frame (502) is provided inside the configuration cavity (1012); a cutter (503) is fixed on the mounting frame (502) for cutting the capsule (202) through the slot (501); a fixing frame (504) is fixed on the upper end of the partition (102); and a cylinder (505) is installed on the fixing frame (504) for pushing the mounting frame (502).
4. The tumor experiment drug preparation device according to claim 3, characterized in that: The anti-overflow connecting component includes a connecting pipe (701) for being sleeved and connected to the outside of the placement cylinder (201), the lower end of the connecting pipe (701) is communicated with the inside of the suction pipe (103), the upper end of the connecting pipe (701) is fixed with a push ring (702), and a plurality of groups of T-shaped rods (703) are fixed on the push ring (702), and the T-shaped rods (703) are slidably connected to the partition (102), and the partition (102) is provided with a lifting component for lifting the connecting pipe (701).
5. The tumor experiment drug preparation device according to claim 4, characterized in that: The lifting assembly includes a circular hole opened on the partition (102), a threaded sleeve (801) is rotatably connected to the circular hole, the outer side of the connecting pipe (701) is threadedly engaged with the inner side of the threaded sleeve (801), a first gear ring (802) is fixed to the outer side of the threaded sleeve (801), and a rack (803) for engaging and transmitting with the first gear ring (802) is fixed on the mounting frame (502).
6. The tumor experiment drug preparation device according to claim 5, characterized in that: The pushing assembly includes a lifting ring (601) for resisting transmission with the push ring (702); the lifting ring (601) is in a sleeve state and slidably connected to the outer side of the placement cylinder (201) by means of a sliding groove and a slider; a connecting rod (602) is provided between the lifting ring (601) and the positioning clamping plate (204); and the two ends of the connecting rod (602) are rotatably connected to the positioning clamping plate (204) and the lifting ring (601) respectively through a pin shaft.
7. The tumor experiment drug preparation device according to claim 2, characterized in that: The air intake control assembly includes an air intake pipe (901) that is connected and fixed to the outside of the placement cylinder (201); a mounting hole (902) is provided on the housing (101); a sliding pipe (903) is slidably connected to the mounting hole (902); a plurality of air intake holes (904) for air intake are provided on the sliding pipe (903); one end of the sliding pipe (903) is located inside the configuration cavity (1012) and is provided with a transmission assembly for transmission with the air intake pipe (901).
8. The tumor experiment drug preparation device according to claim 7, characterized in that: The transmission assembly comprises a conical sleeve (1001) fixed to the end of a sliding tube (903); a conical surface (1002) for abutting against the end of an intake pipe (901) is provided on the outer side of the conical sleeve (1001); a spring (1003) is provided on the outer side of the sliding tube (903); and two ends of the spring (1003) are respectively abutted against the inner wall of the housing (101) and the end of the conical sleeve (1001).
9. The tumor experiment drug preparation device according to claim 2, characterized in that: The adjustment assembly includes a drive ring (301) rotatably connected to the interior of the configuration cavity (1012); the drive ring (301) is fixedly connected to the placement cylinder (201) via a connecting plate (302); and a rotating assembly for rotating the drive ring (301) is provided on the housing (101).
10. The tumor experiment drug preparation device according to claim 9, characterized in that: The rotating assembly comprises a second gear ring (401) fixed to the lower end of the driving ring (301); a mounting shaft (402) is rotatably connected to the housing (101); a gear (403) is fixed to one end of the mounting shaft (402); the gear (403) and the second gear ring (401) are meshed with each other; and a driving motor (404) for driving the mounting shaft (402) is installed on the outer side of the housing (101).
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Intelligent configuration device for biological anti-tumor experimental drugs
CN122605051A