Biological sample cutting device

Abstract

The embodiment of the invention provides a biological sample cutting device, and belongs to the technical field of biological cutting sampling. The biological sample cutting device comprises a base, a cutting table, a cutting mechanism and a positioning mechanism, the cutting table is arranged on the base, the cutting table is used for bearing a sample to be cut, the cutting mechanism is movably arranged on the base in the first direction, and the cutting mechanism is used for cutting the sample on the cutting table; the positioning mechanism is used for positioning a sample on the cutting table, and the first direction is perpendicular to the vertical direction; wherein the cutting table comprises a cutting table body and a supporting plate, the supporting plate is rotatably arranged on the cutting table body along the horizontal plane, and the supporting plate is used for bearing a sample to be cut. The biological sample cutting device is simple in structure, cutting efficiency can be improved, and cutting is more flexible.

Description

Technical Field

[0001] The present application relates to the technical field of biological cutting and sampling, and in particular to a biological sample cutting device. Background Art

[0002] Sampling refers to the process of obtaining individuals or samples from a population, that is, the process of testing or observing the population through the testing of partial samples. Biological cutting sampling is usually used in medical experiments or biological experiments. In order to ensure that the cut test samples can meet the inspection standards, professional biological cutting sampling equipment is required for cutting sampling operations.

[0003] The method for slicing biological samples is usually the traditional manual slicing method. The operator directly touches the blade with his hands, which can easily injure the operator. The cut sample slices have problems such as uneven cutting surface, uneven thickness, and incomplete tissue cutting, which affects subsequent test results and is relatively inefficient. Summary of the Invention

[0004] The embodiments of the present application provide a biological sample cutting device with a simple structure, which can solve the problems mentioned in the background art.

[0005] An embodiment of the present application provides a biological sample cutting device, which includes a base, a cutting table, a cutting mechanism, and a positioning mechanism. The cutting table is arranged on the base, and the cutting table is used to carry the sample to be cut. The cutting mechanism is movably arranged on the base along a first direction, and the cutting mechanism is used to cut the sample on the cutting table. The positioning mechanism is used to position the sample on the cutting table, and the first direction is perpendicular to the vertical direction. The cutting table includes a cutting table body and a support plate, and the support plate is rotatably arranged on the cutting table body along a horizontal plane, and the support plate is used to carry the sample to be cut.

[0006] In this solution, a cutting table, a cutting mechanism, and a positioning mechanism are provided on a base. The cutting table can be used to place a sample (biological sample) to be cut. The positioning mechanism can position the sample on the cutting table to ensure the relative position between the sample and the cutting table. This prevents the sample from moving during cutting by the cutting mechanism, ensuring cutting accuracy. The cutting mechanism is movably provided on the base along a first direction, and the cutting mechanism can adjust its relative position to the sample on the cutting table. The cutting mechanism can adjust the sample to different positions in the first direction, completing precise cutting of the sample. Compared to manual cutting and sampling, the cutting efficiency is higher and the sample cutting accuracy is high, ensuring the accuracy of subsequent sample testing. More importantly, the cutting table includes a cutting table body and a support plate. After the sample to be cut is placed on the support plate, the support plate is rotatably provided on the cutting table body along a horizontal plane. This allows the support plate to be rotated to adjust the relative angle between the sample on the support plate and the cutting mechanism, thereby completing multiple cuts of the sample at various angles. This improves cutting efficiency and eliminates the need for manual movement and rotation of the sample on the support plate, better meeting the actual needs of sample cutting.

[0007] In some embodiments, a slewing bearing is provided between the cutting table body and the supporting plate, the inner ring of the slewing bearing is connected to the cutting table body, and the outer ring of the slewing bearing is connected to the supporting plate.

[0008] In the above technical solution, the slewing bearing provides a rotational connection between the support plate and the cutting table body, providing high rotational stability. Furthermore, the operator can manually adjust the relative angle between the support plate and the cutting mechanism based on the sample on the support plate and the cutting mechanism's cutting requirements, providing greater flexibility.

[0009] In some embodiments, the cutting mechanism includes a bracket, a lifting assembly and a cutting assembly. A first driving mechanism is provided on the base for driving the bracket to move in a first direction. The lifting assembly is provided between the bracket and the cutting assembly. The lifting assembly is used to drive the cutting assembly to move in a third direction to approach or move away from the cutting table. The third direction is perpendicular to the first direction and is a vertical direction.

[0010] In the above technical solution, the first drive mechanism is configured to drive the bracket to move in a first direction, thereby adjusting the relative position of the cutting assembly and the sample on the cutting table in the first direction according to the sample cutting requirements, thereby achieving precise cutting of the sample. The lifting assembly is configured to drive the cutting assembly to move in a third direction, thereby approaching or moving away from the sample on the cutting table, thereby achieving cutting operations on the sample on the cutting table.

[0011] In some embodiments, the bracket is a gantry, which includes two columns and a beam connected between the two columns, the beam extends along the second direction, and the lifting assembly is connected to the beam; the number of first drive mechanisms is set to two groups, and the two groups of first drive mechanisms correspond to the two columns one by one, and the first direction, the second direction and the third direction are perpendicular to each other; the first drive mechanism includes a first screw rod, a first drive motor and a first nut seat, and a first mounting groove is provided on the base, and the first screw rod and the first drive motor are installed in the first mounting groove, and the first screw rod extends along the first direction, and one end of the first drive motor is connected to the first screw rod for driving the first screw rod to rotate; the other end of the first screw rod is rotatably installed in the first mounting groove through a bearing, and the first nut seat is threadedly matched with the first screw rod, and a first sliding part is provided at the lower end of the column, and the first sliding part is fixedly connected to the first nut seat.

[0012] In the above technical solution, by adopting a gantry structure as the support, the gantry is a gate-shaped frame, and by using two sets of first drive mechanisms, the two first drive mechanisms work synchronously and cooperate with the drive of the two columns of the support. Compared with a cantilever structure, the gantry support has higher stability and the movement of the support in the first direction is more stable. By adopting a screw-nut substructure as the first drive mechanism, the first screw is driven to rotate under the drive action of the first drive motor. Under the limiting action of the two first drive mechanisms, the first screw drives the first sliding portion on the first nut seat to move only in the first direction, thereby realizing the position adjustment of the support in the first direction and achieving high precision in the position movement of the support.

[0013] In some embodiments, the lifting assembly includes a first lifting drive member, which is installed on the crossbeam of the bracket. The telescopic end of the first lifting drive member is connected to the cutting assembly, and is used to drive the cutting assembly to move along the third direction to approach or move away from the cutting table; the cutting assembly includes a knife holder and a cutter, and the cutter is extended along the second direction, and the cutter is detachably connected to the knife holder.

[0014] In the above technical solution, a first lifting drive member is provided, which is connected to the crossbeam of the support. The first lifting drive member drives the cutting assembly to move along the third direction to perform cutting operations on the sample on the cutting table. The cutting assembly includes a knife holder and a cutter. The knife holder serves to fix and install the knife. The cutter extends along the second direction and is detachably connected to the knife holder, facilitating replacement of the cutter.

[0015] In some embodiments, a cleaning mechanism for cleaning the cutter is provided on the knife holder, the cleaning mechanism including a first transverse driving member, a cleaning frame and a scraper, the first transverse driving member is installed on one side of the knife holder, the first transverse driving member is used to drive the cleaning frame to move along the second direction, the cleaning frame is a U-shaped frame body, the cleaning frame includes two abutting sections and a connecting section connected between the two abutting sections, the connecting section is connected to the first transverse driving member, the two abutting sections are respectively located on the front and back sides of the cutter; the scraper is a U-shaped structure, the openings of the scraper and the cleaning frame are arranged opposite to each other up and down, the opening of the cleaning frame is arranged downward, the scraper is arranged on the opposite side of the two abutting sections, a cleaning strip is provided on the scraper, and the first transverse driving member is used to drive the cleaning frame to move along the second direction to clean the cutter through the cleaning strip on the scraper.

[0016] In the above technical solution, a cleaning mechanism is provided on the knife holder, and a first transverse driving member in the cleaning mechanism can provide driving force to drive the cleaning frame to move along the second direction. In this way, the cleaning strip of the scraper on the cleaning frame can be used to wipe, clean and disinfect the cutter. After the sample is cut, there is no need for manual disinfection and cleaning of the cutter, which reduces the operator's workload and increases the degree of automation. In addition, the cleaning frame and the scraper are U-shaped, and the openings of the scraper and the cleaning frame are arranged relative to each other in the upper and lower directions, with the opening of the cleaning frame facing downward. In this way, the U-shaped scraper covers the lower half of the cutter, which can relatively completely cover the lower half of the cutter, especially the lower edge of the cutter's blade, achieving precise cleaning of the cutter and better cleaning and disinfection effects on the cutter.

[0017] In some embodiments, along the second direction, the cleaning frame has a first position and a second position. When the cleaning frame is in the first position, the cleaning frame and the cutter are staggered, and the cleaning frame is located on one side of the cutter in the second direction; when the cleaning frame is in the second position, the cleaning strip on the scraper on the cleaning frame contacts the cutter.

[0018] In the above technical solution, taking into account the phenomenon that the cleaning mechanism and the position of the cutter will not interfere with each other, an idle position is provided on one side of the second direction of the knife holder. When the cleaning frame is in the first position, that is, the cleaning frame and the cutter are staggered. When the cleaning frame is in the second position, the cleaning strip on the scraper on the cleaning frame contacts the cutter, so that when the cutter cuts the sample, at least the cleaning frame and the cutter are staggered in the second direction, which will not affect the normal cutting operation of the cutter.

[0019] In some embodiments, a first spring is provided between the upper end of the scraper and the cleaning frame, and the first spring is used to enable the scraper to move relative to the cleaning frame along a third direction; along the third direction, the scraper has a third position and a fourth position, when the scraper is in the third position, the cleaning frame is in the first position, and the lower end of the scraper is located above the lower end of the cutter, and the first spring is in a normal state; when the scraper is in the fourth position, the cleaning frame is in the second position, and the lower end of the scraper is flush with the lower end of the cutter, and the first spring is stretched and accumulates elastic potential energy; wherein, a guide slope is provided on the side of the cutter close to the first position of the cleaning frame, and the guide slope is used to contact the lower end of the scraper with the guide slope when the cleaning frame moves from the first position to the second position, and squeeze the scraper to guide the scraper to move from the third position to the fourth position, and the first spring accumulates elastic potential energy.

[0020] In the above technical solution, although the cleaning frame and the cutter are staggered in the second direction, how to take into account the scraper on the cleaning frame to be able to better clean the cutter, that is, the scraper can wrap the cutter, then the lower end of the scraper needs to be lower than the height of the cutter, but in the third direction, the cutter and the scraper are prone to interference, which will affect the normal cutting of the cutter.

[0021] Therefore, a first spring is provided between the upper end of the scraper and the cleaning frame, and a guide bevel is provided on the side of the cutter near the first position of the cleaning frame. When the scraper is in the third position, the cleaning frame is in the first position, the first spring is in a normal state, and the lower end of the scraper is located above the lower end of the cutter, so that the scraper does not affect the normal cutting of the cutter. When the sample cutting operation is completed and the cutter needs to be cleaned, the first transverse drive member drives the cleaning frame from the first position to the second position. Under the guidance of the guide bevel, the lower end of the scraper first contacts the guide bevel, and then the guide bevel acts as a guide, squeezing the scraper downward, driving the scraper to move vertically from the third position to the fourth position. At this time, the first spring is automatically stretched, and the first spring accumulates elastic potential energy, so that the scraper can wrap around the cutter, completing the cleaning operation of the cutter. The structure is simple. Therefore, this design can not only ensure the cleaning effect of the scraper on the cutter, but also realize the independent operation of the cleaning mechanism and the cutter, without interference between the two.

[0022] In some embodiments, the positioning mechanism includes a first adsorption part, which includes multiple adsorption holes. The multiple adsorption holes are distributed in an array on the support plate. The multiple adsorption holes are connected to the vacuum equipment through pipelines. The adsorption holes are used to adsorb samples on the support plate to adsorb and position the samples.

[0023] In the above technical solution, multiple adsorption holes are arranged on the support plate, and the multiple adsorption holes are connected to the vacuum equipment. The vacuum equipment is used to generate negative pressure adsorption force in the hole portion of the adsorption hole to adsorb and position the sample. The adsorption and positioning effect of the sample is good. In this way, when the cutting mechanism cuts the sample, the sample is not likely to move relative to the support plate.

[0024] In some embodiments, the positioning mechanism includes a pressure plate, which is liftably arranged on the tool holder. A second lifting drive member is provided between the pressure plate and the tool holder, and the second lifting drive member is used to drive the pressure plate to move along a third direction to approach or move away from the support plate.

[0025] In the above technical solution, the positioning mechanism is in the form of a pressure plate, the pressure plate and the knife holder complement each other, and the cutting assembly is used to lower the pressure plate to contact the sample before cutting the sample, thereby completing the compression and positioning of the sample. In this way, when the cutting mechanism cuts the sample, the sample is not likely to move relative to the support plate.

[0026] Other features and advantages of the present application will be described in detail in the subsequent detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following is a brief introduction to the drawings required for use in the embodiments. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without creative work.

[0028] Figure 1 A front cross-sectional view of a biological sample cutting device provided in some embodiments of the present application; Figure 2 A top view of a biological sample cutting device provided in some embodiments of the present application; Figure 3 for Figure 1 A is an enlarged schematic diagram; Figure 4 for Figure 1 A magnified schematic diagram of middle B; Figure 5 A side sectional view of a blade holder in a biological sample cutting device provided in some embodiments of the present application; Figure 6 Schematic diagram of the structure of the scraper and cleaning strip of the cleaning mechanism provided in some embodiments of the present application.

[0029] Icons: Biological sample cutting device 100, base 10, first driving mechanism 11, first screw 111, first driving motor 112, first nut seat 114, first mounting slot 12, supporting foot 13, cutting table 20, cutting table body 21, supporting plate 22, adsorption hole 221, slewing bearing 23, locking nut 24, cutting mechanism 30, bracket 31, column 311, first sliding part 3111, crossbeam 312, second electric push rod 313, lifting assembly 32, The first lifting drive member 321, the cutting assembly 33, the knife holder 331, the cutter 332, the guide slope 3321, the cleaning mechanism 40, the first transverse driving member 41, the second driving motor 411, the second screw rod 412, the second guide rod 413, the cleaning frame 42, the abutting section 421, the connecting section 422, the scraper 43, the cleaning strip 431, the first spring 44, the positioning mechanism 50, the pressure plate 51, the second lifting drive member 52, the first direction X, the second direction Y, and the third direction Z. DETAILED DESCRIPTION

[0030] To make the objectives, technical solutions, and advantages of the embodiments of the present application more clear, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Generally, the components of the embodiments of the present application described and shown in the drawings herein can be arranged and designed in various different configurations.

[0031] Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the present application for protection, but merely represents selected embodiments of the present application. All other embodiments obtained by persons of ordinary skill in the art based on the embodiments in the present application without creative work are within the scope of protection of the present application.

[0032] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not need to be further defined or explained in subsequent drawings.

[0033] In the description of the embodiments of this application, it should be noted that the indicated orientations or positional relationships are based on the orientations or positional relationships shown in the accompanying drawings, or the orientations or positional relationships in which the product of the application is typically placed when in use. These are merely for the convenience of describing this application and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the terms "first," "second," "third," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0034] It should also be noted that, in the description of this application, unless otherwise expressly specified or limited, the terms "disposed" and "connected" should be understood broadly. For example, they can refer to fixed connection, detachable connection, or integral connection; they can refer to direct connection, indirect connection through an intermediate medium, or internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on the specific circumstances. Example

[0035] This embodiment of the present application provides a biological sample cutting device, please refer to Figures 1 to 6 The biological sample cutting device 100 includes a base 10, a cutting table 20, a cutting mechanism 30, and a positioning mechanism 50. The cutting table 20 is disposed on the base 10 and is used to carry a sample to be cut. The cutting mechanism 30 is movably disposed on the base 10 along a first direction X. The cutting mechanism 30 is used to cut the sample on the cutting table 20. The positioning mechanism 50 is used to position the sample on the cutting table 20. The first direction X is perpendicular to the vertical direction. The cutting table 20 includes a cutting table body 21 and a support plate 22. The support plate 22 is rotatably disposed on the cutting table body 21 along a horizontal plane and is used to carry the sample to be cut.

[0036] In this embodiment, a cutting table 20, a cutting mechanism 30, and a positioning mechanism 50 are provided on a base 10. The cutting table 20 is provided for placing a sample (biological sample) to be cut, and the positioning mechanism 50 positions the sample on the cutting table 20, ensuring the relative position of the sample and the cutting table 20. This prevents the sample from moving during cutting by the cutting mechanism 30, thereby ensuring the cutting accuracy of the cutting mechanism 30. The cutting mechanism 30 is movably provided on the base 10 along a first direction X. The cutting mechanism 30 can adjust its relative position to the sample on the cutting table 20. The cutting mechanism 30 can adjust the sample to different positions in the first direction X to achieve precise cutting of the sample. Compared to manual cutting and sampling, the cutting efficiency is higher and the sample cutting accuracy is high, ensuring the accuracy of subsequent sample testing. More importantly, by making the cutting table 20 include a cutting table body 21 and a support plate 22, after the sample to be cut is placed on the support plate 22, the support plate 22 is rotatably set on the cutting table body 21 along the horizontal plane. In this way, the relative angle relationship between the sample on the support plate 22 and the cutting mechanism 30 can be adjusted by rotating the support plate 22, and multiple cuts of the sample at various angles can be completed, with higher cutting efficiency. There is no need to manually move and rotate the sample on the support plate 22, which can better meet the actual needs of sample cutting.

[0037] The device is mainly used in biological laboratories to cut biological samples. The samples can be various plant or animal samples, for example, seaweed samples. The bottom of the base 10 is provided with a plurality of support legs 13, and the plurality of support legs 13 are distributed at the four corners of the bottom of the base 10.

[0038] In some embodiments, please combine Figure 1 and Figure 3 A slewing bearing 23 is disposed between the cutting table body 21 and the support plate 22. The inner ring of the slewing bearing 23 is connected to the cutting table body 21, while the outer ring of the slewing bearing 23 is connected to the support plate 22. This arrangement of the slewing bearing 23 ensures a rotational connection between the support plate 22 and the cutting table body 21, providing high rotational stability. Furthermore, the operator can manually adjust the relative angle between the support plate 22 and the cutting mechanism 30, thereby adjusting the cutting angle, based on the sample on the support plate 22 and the cutting mechanism 30's cutting requirements, providing greater flexibility.

[0039] The support plate 22 can be driven to rotate in a variety of ways. The support plate 22 can be manually applied with force to achieve rotation of the support plate 22, or it can be driven by a motor. Of course, in the case of manually applying force to the support plate 22, in order to achieve rotational locking and positioning of the support plate 22, the support plate 22 can be provided with a locking nut 24. The locking nut 24 is threadedly engaged with the support plate 22. One end of the locking nut 24 passes through the support plate 22 and abuts against the surface of the cutting table body 21 to limit relative rotation of the support plate 22 and the cutting table body 21.

[0040] When the support plate 22 is driven by a motor to rotate, the outer ring of the slewing bearing 23 is toothed, which can be achieved by a first driving member. The first driving member is a rotating motor, which is installed on the cutting table body 21. The first driving member is connected to the teeth of the outer ring of the slewing bearing 23. The slewing bearing 23 is driven to rotate by the first driving member, thereby realizing the rotation of the support plate 22. In this way, there is no need for manual rotation of the support plate 22, which is more labor-saving and has a higher degree of automation.

[0041] In some embodiments, the cutting mechanism 30 includes a support 31, a lifting assembly 32, and a cutting assembly 33. A first drive mechanism 11 is provided on the base 10 for driving the support 31 in a first direction X. The lifting assembly 32 is disposed between the support 31 and the cutting assembly 33. The lifting assembly 32 is configured to drive the cutting assembly 33 in a third direction Z, perpendicular to the first direction X, to move closer to or further from the cutting table 20. The third direction Z is perpendicular to the first direction X and is a vertical direction. The first drive mechanism 11 can drive the support 31 in the first direction X, thereby adjusting the relative position of the cutting assembly 33 and the sample on the cutting table 20 in the first direction X according to the sample cutting requirements, thereby achieving precise cutting of the sample. The lifting assembly 32 can also drive the cutting assembly 33 in the third direction Z, thereby moving closer to or further away from the sample on the cutting table 20, thereby achieving cutting operations on the sample on the cutting table 20.

[0042] In some embodiments, please combine Figure 1 and Figure 2The bracket 31 is a gantry, and the bracket 31 includes two columns 311 and a beam 312 connected between the two columns 311. The beam 312 extends along the second direction Y, and the lifting assembly 32 is connected to the beam 312; the number of the first driving mechanism 11 is set to two groups, and the two groups of first driving mechanisms 11 correspond to the two columns 311 one by one, and the first direction X, the second direction Y and the third direction Z are perpendicular to each other; the first driving mechanism 11 includes a first screw rod 111, a first driving motor 112 and a first nut seat 114, and a first The mounting groove 12, the first screw rod 111 and the first drive motor 112 are installed in the first mounting groove 12, the first screw rod 111 is extended along the first direction X, one end of the first drive motor 112 is connected to the first screw rod 111, and is used to drive the first screw rod 111 to rotate; the other end of the first screw rod 111 is rotatably mounted in the first mounting groove 12 through a bearing, the first nut seat 114 is threadedly engaged with the first screw rod 111, and the lower end of the column 311 is provided with a first sliding portion 3111, which is fixedly connected to the first nut seat 114. By adopting a gantry structure for the bracket 31, the gantry is a door-shaped frame, and the two first drive mechanisms 11 are used, and the two first drive mechanisms 11 work synchronously and cooperate with the drive of the two columns 311 of the bracket 31. Compared with a cantilever structure of the bracket 31, the gantry bracket 31 has higher stability, and the movement of the bracket 31 in the first direction X is more stable. By adopting a screw-nut pair structure for the first driving mechanism 11, the first screw 111 is driven to rotate under the driving action of the first driving motor 112. Under the synchronous driving action of the two groups of first driving mechanisms 11, the first screw 111 drives the first sliding part 3111 on the first nut seat 114 to move only along the first direction X, thereby realizing the position adjustment of the bracket 31 in the first direction X, and the position movement accuracy of the bracket 31 is high.

[0043] The first drive motor 112 may be a servo motor, and the two sets of first drive mechanisms 11 are controlled by the same control system. The two sets of first drive mechanisms 11 rotate forward or reverse synchronously, thereby adjusting the position of the bracket 31 in the first direction X. Of course, the base 10 may also be provided with a slide rail or a slide groove, which slidably cooperates with the first sliding portion 3111 to guide the first sliding portion 3111 to move along the first direction X, thereby improving the stability of the bracket 31 during movement.

[0044] In some embodiments, please refer to Figure 1The lifting assembly 32 includes a first lifting drive 321 mounted on the crossbeam 312 of the support 31. The telescopic end of the first lifting drive 321 is connected to the cutting assembly 33, and is used to drive the cutting assembly 33 to move along the third direction Z to move closer to or away from the cutting table 20. The cutting assembly 33 includes a blade holder 331 and a cutter 332. The cutter 332 extends along the second direction Y and is detachably connected to the blade holder 331. The first lifting drive 321 is connected to the crossbeam 312 of the support 31, and the first lifting drive 321 drives the cutting assembly 33 to move along the third direction Z, thereby cutting the sample on the cutting table 20. The cutting assembly 33 includes a knife seat 331 and a cutter 332. The knife seat 331 serves the function of fixing and installing. The cutter 332 is extended along the second direction Y. The cutter 332 and the knife seat 331 are detachably connected to each other, which facilitates the replacement of the cutter 332.

[0045] The first lifting drive member 321 can be a linear drive member such as a hydraulic cylinder, a pneumatic cylinder, or an electric push rod. In this embodiment, the first lifting drive member 321 is a first electric push rod. The knife holder 331 has a knife groove for mounting the cutter 332. The knife holder 331 is provided with a locking member. The locking member is threadedly engaged with the knife holder 331. One end of the locking member extends into the knife groove to support the cutter 332 and achieve positioning and installation of the cutter 332. When the cutter 332 needs to be removed, it is only necessary to loosen the locking member, making the cutter 332 easy and quick to disassemble and install. There are multiple locking members, and the multiple locking members are spaced apart along the second direction Y on at least one side of the knife holder 331.

[0046] In addition, please refer to Figure 1 A second electric push rod 313 can also be provided on the beam 312. The second electric push rod 313 is connected to the first lifting drive member 321. The second electric push rod 313 can drive the first lifting drive member 321 and the cutting assembly 33 to move along the second direction Y. In this way, the cutting assembly 33 can realize position adjustment in the first direction X, the second direction Y and the third direction Z, which is more flexible and can meet more cutting requirements.

[0047] In some embodiments, please combine Figure 4 、 Figure 5 and Figure 6The knife holder 331 is provided with a cleaning mechanism 40 for cleaning the cutter 332. The cleaning mechanism 40 includes a first transverse driving member 41, a cleaning frame 42 and a scraper 43. The first transverse driving member 41 is installed on one side of the knife holder 331. The first transverse driving member 41 is used to drive the cleaning frame 42 to move along the second direction Y. The cleaning frame 42 is a U-shaped frame. The cleaning frame 42 includes two abutting sections 421 and a connecting section 422 connected between the two abutting sections 421. The connecting section 422 is connected to the first The first transverse driving member 41 is connected to the cutter 332, and the two abutting sections 421 are respectively located on the front and back sides of the cutter 332. The scraper 43 has a U-shaped structure, and the openings of the scraper 43 and the cleaning rack 42 are arranged vertically opposite each other, with the opening of the cleaning rack 42 facing downward. The scraper 43 is arranged on the opposite side of the two abutting sections 421. The scraper 43 is provided with a cleaning strip 431. The first transverse driving member 41 is used to drive the cleaning rack 42 to move in the second direction Y, so that the cleaning strip 431 on the scraper 43 can clean the cutter 332. By providing a cleaning mechanism 40 on the cutter holder 331, the first transverse driving member 41 in the cleaning mechanism 40 can provide driving force to drive the cleaning rack 42 to move in the second direction Y. In this way, the cleaning strip 431 on the scraper 43 on the cleaning rack 42 can wipe, clean and disinfect the cutter 332. After the sample is cut, manual disinfection and cleaning of the cutter 332 is no longer required, reducing the operator's workload and achieving a higher degree of automation. In addition, the cleaning frame 42 and the scraper 43 adopt a U-shaped structure, and the openings of the scraper 43 and the cleaning frame 42 are arranged opposite to each other up and down, and the opening of the cleaning frame 42 is arranged downward, so that the U-shaped scraper 43 covers the lower half of the cutter 332, and can more completely cover the lower half of the cutter 332, especially the lower edge of the blade of the cutter 332, thereby achieving precise cleaning of the cutter 332 and better cleaning and disinfection effect of the cutter 332.

[0048] The cleaning strip 431 can be an alcohol swab. The first transverse driving member 41 can be a screw-nut sub-mechanism, comprising a second drive motor 411, a second screw rod 412, and a second guide rod 413. The knife holder 331 has a receiving groove for partially mounting the first transverse driving member 41. The second screw rod 412 is rotatably mounted in the receiving groove of the knife holder 331. The second screw rod 412 extends along the second direction Y. The second drive motor 411 is drivably connected to the second screw rod 412 for driving the second screw rod 412 to rotate. The second guide rod 413 is mounted in the receiving groove. The connecting section 422 of the cleaning frame 42 is threadedly engaged with the second screw rod 412, and the connecting section 422 is passed through the second guide rod 413. Driven by the second drive motor 411, the cleaning frame 42 moves along the second direction Y.

[0049] In some embodiments, the cleaning rack 42 has a first position and a second position along the second direction Y. When the cleaning rack 42 is in the first position, the cleaning rack 42 is offset from the cutter 332 and is located on one side of the cutter 332 in the second direction Y. When the cleaning rack 42 is in the second position, the cleaning strip 431 on the scraper 43 on the cleaning rack 42 contacts the cutter 332. To prevent interference between the cleaning mechanism 40 and the cutter 332, an idle position is provided on one side of the blade holder 331 in the second direction Y. When the cleaning rack 42 is in the first position, that is, the cleaning rack 42 is offset from the cutter 332, when the cleaning rack 42 is in the second position, the cleaning strip 431 on the scraper 43 on the cleaning rack 42 contacts the cutter 332. This ensures that when the cutter 332 cuts a sample, at least the cleaning rack 42 and the cutter 332 are offset in the second direction Y, without affecting the normal cutting operation of the cutter 332.

[0050] In some embodiments, please refer to Figure 5A first spring 44 is provided between the upper end of the scraper 43 and the cleaning frame 42. The first spring 44 is used to enable the scraper 43 to move relative to the cleaning frame 42 along the third direction Z. Along the third direction Z, the scraper 43 has a third position and a fourth position. When the scraper 43 is in the third position, the cleaning frame 42 is in the first position, and the lower end of the scraper 43 is located above the lower end of the cutter 332. The first spring 44 is in a normal state. When the scraper 43 is in the fourth position, the cleaning frame 42 is in the second position. , and the lower end of the scraper 43 is flush with the lower end of the cutter 332, the first spring 44 is stretched and accumulates elastic potential energy; wherein, a guide bevel 3321 is provided on the side of the cutter 332 near the first position of the cleaning frame 42. The guide bevel 3321 is used to contact the lower end of the scraper 43 with the guide bevel 3321 when the cleaning frame 42 moves from the first position to the second position, and squeeze the scraper 43 and then guide the scraper 43 to move from the third position to the fourth position, and the first spring 44 accumulates elastic potential energy. Although the cleaning frame 42 and the cutter 332 are offset in the second direction Y, how to ensure that the scraper 43 on the cleaning frame 42 can effectively clean the cutter 332, that is, how to ensure that the scraper 43 can wrap around the cutter 332, then the lower end of the scraper 43 must be lower than the height of the cutter 332. However, in the third direction Z, the cutter 332 and the scraper 43 are prone to interference, which will affect the normal cutting of the cutter 332. Therefore, a first spring 44 is provided between the upper end of the scraper 43 and the cleaning frame 42, and a guide slope 3321 is provided on the side of the cutter 332 close to the first position of the cleaning frame 42, so that when the scraper 43 is in the third position, the cleaning frame 42 is in the first position, and the first spring 44 is in a normal state. At this time, the lower end of the scraper 43 is located above the lower end of the cutter 332, and the scraper 43 will not affect the normal cutting of the cutter 332. After the sample is cut, if the cutter 332 needs to be cleaned, the first transverse drive member 41 drives the cleaning frame 42 from the first position to the second position. The scraper 43, guided by the guide bevel 3321, first contacts the guide bevel 3321 at its lower end. The guide bevel 3321 then guides the scraper 43 downward, driving the scraper 43 vertically from the third position to the fourth position. At this point, the first spring 44 is automatically stretched, accumulating elastic potential energy. This allows the scraper 43 to wrap around the cutter 332, completing the cleaning operation. This simple design ensures that the scraper 43 cleans the cutter 332 while also enabling the cleaning mechanism 40 and the cutter 332 to operate independently, without interference.

[0051] In some embodiments, please refer to Figure 2The positioning mechanism 50 includes a first adsorption member, which includes a plurality of adsorption holes 221. The plurality of adsorption holes 221 are arranged in an array on the support plate 22 and are connected to a vacuum device via a pipeline. The adsorption holes 221 are used to adsorb the sample on the support plate 22 to position the sample. The plurality of adsorption holes 221 on the support plate 22 are connected to the vacuum device, and the vacuum device generates a negative pressure adsorption force on the holes of the adsorption holes 221 to adsorb and position the sample. This provides a good adsorption and positioning effect for the sample. This prevents the sample from moving relative to the support plate 22 when the cutting mechanism 30 cuts the sample.

[0052] The plurality of adsorption holes 221 can be divided into a plurality of groups and spaced apart on the support plate 22. The plurality of adsorption holes 221 in each group of adsorption holes 221 can be distributed in a circular array or a rectangular array. In this embodiment, the plurality of adsorption holes 221 in each group of adsorption holes are distributed in a rectangular array.

[0053] In some embodiments, please refer to Figure 5 The positioning mechanism 50 includes a pressure plate 51, which is movably mounted on the knife holder 331. A second lifting drive 52 is disposed between the pressure plate 51 and the knife holder 331. The second lifting drive 52 is used to drive the pressure plate 51 to move along the third direction Z to move closer to or away from the support plate 22. By adopting the pressure plate 51 as the positioning mechanism 50, the pressure plate 51 and the knife holder 331 complement each other. Before cutting the sample, the pressure plate 51 is lowered to abut against the sample by the cutting assembly 33, thereby completing the compression and positioning of the sample. In this way, when the cutting mechanism 30 cuts the sample, the sample is less likely to move relative to the support plate 22.

[0054] The pressing plate 51 extends along the second direction Y, and the second lifting driving member 52 is an electric push rod.

[0055] It should be noted that, unless there is any conflict, the features in the embodiments of this application can be combined with each other.

[0056] The above description is merely a preferred embodiment of the present application and is not intended to limit the present application. Various modifications and variations are possible for those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present application shall be included within the scope of protection of the present application.

Claims

1. A biological sample cutting device, characterized in that: The cutting machine comprises a base, a cutting table, a cutting mechanism, and a positioning mechanism, wherein the cutting table is arranged on the base and is used to carry a sample to be cut, the cutting mechanism is movably arranged on the base along a first direction and is used to cut the sample on the cutting table, and the positioning mechanism is used to position the sample on the cutting table, wherein the first direction is perpendicular to the vertical direction; The cutting table includes a cutting table body and a supporting plate. The supporting plate is rotatably arranged on the cutting table body along a horizontal plane. The supporting plate is used to carry the sample to be cut.

2. The biological sample cutting device according to claim 1, wherein: A slewing bearing is provided between the cutting table body and the supporting plate. The inner ring of the slewing bearing is connected to the cutting table body, and the outer ring of the slewing bearing is connected to the supporting plate.

3. The biological sample cutting device according to claim 1, wherein: The cutting mechanism includes a bracket, a lifting assembly and a cutting assembly. The base is provided with a first driving mechanism for driving the bracket to move along the first direction. The lifting assembly is arranged between the bracket and the cutting assembly. The lifting assembly is used to drive the cutting assembly to move along a third direction to approach or move away from the cutting table. The third direction is perpendicular to the first direction and is a vertical direction.

4. The biological sample cutting device according to claim 3, wherein: The support is a gantry, comprising two upright posts and a crossbeam connected between the two upright posts, the crossbeam extending along the second direction, and the lifting assembly connected to the crossbeam; The number of the first driving mechanisms is set to two groups, and the two groups of the first driving mechanisms correspond to the two pillars respectively, and the first direction, the second direction and the third direction are perpendicular to each other; The first driving mechanism includes a first screw rod, a first driving motor and a first nut seat. A first mounting groove is provided on the base. The first screw rod and the first driving motor are installed in the first mounting groove. The first screw rod extends along the first direction. One end of the first driving motor is connected to the first screw rod to drive the first screw rod to rotate; the other end of the first screw rod is rotatably installed in the first mounting groove through a bearing. The first nut seat is threadedly engaged with the first screw rod. The lower end of the column is provided with a first sliding portion, and the first sliding portion is fixedly connected to the first nut seat.

5. The biological sample cutting device according to claim 3, wherein: The lifting assembly includes a first lifting drive member, the first lifting drive member is mounted on the crossbeam of the bracket, and the telescopic end of the first lifting drive member is connected to the cutting assembly, and is used to drive the cutting assembly to move along the third direction to approach or move away from the cutting table; The cutting assembly includes a knife seat and a cutter. The cutter is extended along the second direction, and the cutter is detachably connected to the knife seat.

6. The biological sample cutting device according to claim 5, wherein: The cleaning mechanism of claim 1, wherein the cleaning mechanism comprises a first transverse driving member, a cleaning frame and a scraper, the first transverse driving member being mounted on one side of the knife seat, the first transverse driving member being used to drive the cleaning frame to move along the second direction, the cleaning frame being a frame body of a U-shaped structure, the cleaning frame comprising two abutment sections and a connecting section connected between the two abutment sections, the connecting section being connected to the first transverse driving member, the two abutment sections being located on the front and back sides of the cutter respectively; the scraper is a U-shaped structure, the openings of the scraper and the cleaning frame being arranged opposite to each other up and down, the opening of the cleaning frame being arranged downward, the scraper being arranged on the opposite side of the two abutment sections, a cleaning strip being provided on the scraper, and the first transverse driving member being used to drive the cleaning frame to move along the second direction to clean the cutter through the cleaning strip on the scraper.

7. The biological sample cutting device according to claim 6, wherein: Along the second direction, the cleaning frame has a first position and a second position. When the cleaning frame is in the first position, the cleaning frame and the cutter are offset, and the cleaning frame is located on one side of the cutter in the second direction; when the cleaning frame is in the second position, the cleaning strip on the scraper on the cleaning frame contacts the cutter.

8. The biological sample cutting device according to claim 7, wherein: A first spring is provided between the upper end of the scraper and the cleaning frame, and the first spring is used to enable the scraper to move relative to the cleaning frame along the third direction; along the third direction, the scraper has a third position and a fourth position, when the scraper is in the third position, the cleaning frame is in the first position, and the lower end of the scraper is located above the lower end of the cutter, and the first spring is in a normal state; when the scraper is in the fourth position, the cleaning frame is in the second position, and the lower end of the scraper is flush with the lower end of the cutter, the first spring is stretched and accumulates elastic potential energy; In which, a guide slope is provided on the side of the cutter close to the first position of the cleaning frame, and the guide slope is used for contacting the lower end of the scraper with the guide slope when the cleaning frame moves from the first position to the second position, and squeezing the scraper to guide the scraper to move from the third position to the fourth position, and the first spring accumulates elastic potential energy.

9. The biological sample cutting device according to claim 1, wherein: The positioning mechanism includes a first adsorption part, which includes a plurality of adsorption holes. The plurality of adsorption holes are distributed in an array on the support plate. The plurality of adsorption holes are connected to the vacuum equipment through pipelines. The adsorption holes are used to adsorb samples on the support plate to adsorb and position the samples.

10. The biological sample cutting device according to claim 5, wherein: The positioning mechanism includes a pressing plate, which is liftably arranged on the tool holder. A second lifting drive member is provided between the pressing plate and the tool holder, and the second lifting drive member is used to drive the pressing plate to move along the third direction to approach or move away from the support plate.

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