A 6-channel lyophilized single-serve chemiluminescence instrument

Abstract

The present application relates to the field of chemiluminescence instrument, specifically to a 6-channel freeze-drying single-portion chemiluminescence instrument, which comprises an instrument device for chemiluminescence detection of detection reagents and added reagents, and a rotating door connected to the outer side of the instrument device through a hinge; a detection mechanism for storing and processing the detection reagents fixed and dried by freeze-drying, which is arranged in the interior of the instrument device; and a test mechanism for storing and processing the added reagents after freeze-drying, which is arranged in the interior of the instrument device. When the closure door is deflected outward to a first predetermined angle, the detection mechanism will automatically move to the position of the closure door, so as to put the test tube into the closure door and make a good preparation for subsequent detection.

Description

Technical Field

[0001] This invention relates to the field of chemiluminescence instrument technology, specifically a 6-channel freeze-dried single-person chemiluminescence instrument. Background Technology

[0002] Chemiluminescence refers to the phenomenon in certain chemical reactions where reaction products release energy in the form of light when they transition from an excited state to a ground state via electronic transitions. Chemiluminescence instruments detect this light signal for quantitative or qualitative analysis. For example, in the luminol-hydrogen peroxide system, luminol is oxidized by hydrogen peroxide under alkaline conditions to produce an excited-state intermediate. When this intermediate returns to its ground state, it emits blue fluorescence. By detecting the fluorescence intensity, the content of the relevant substance can be determined.

[0003] The existing freeze-dried single-person chemiluminescence instruments have the following problems: the existing detection reagents and additive reagents are all in liquid form. When the two are mixed together and the operator mistakenly believes that the chemiluminescence instrument is turned on, the two will react prematurely, thus missing the optimal detection period; the detection process is carried out manually or electrically, which increases labor and costs; in addition, the existing instruments all use a lot of electricity and manpower to drive the rotating door, test tubes and feeding equipment separately, which increases labor and electricity costs. Summary of the Invention

[0004] The present invention provides a 6-channel freeze-drying single-person chemiluminescence instrument to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a channel freeze-drying single-person chemiluminescence instrument, comprising an instrument for chemiluminescence detection of detection reagents and additive reagents, wherein a rotating door is connected to the outside of the instrument via a hinge;

[0006] A test device for storing test reagents that have been fixed and dried by freeze-drying, the test device being disposed inside the instrument.

[0007] A testing mechanism for storing and treating lyophilized additives, the testing mechanism being located inside the instrument / equipment;

[0008] A discharge mechanism is used to remove the mixed substance after chemical emission detection is completed, and the discharge mechanism is located inside the instrument.

[0009] The instrument is fixedly connected to a support on its outer side, and a fixed shaft is rotatably connected inside the support. A closed door is fixedly installed on the outer side of the fixed shaft.

[0010] Preferably, a tension strip is fixedly connected to the outer end face of the closed door, and the end of the tension strip away from the closed door is connected to the testing mechanism. The tension strip passes through the outside of the instrument and extends into its interior.

[0011] The closed door and the fixed shaft deflect outward within the support, and the force is transmitted through the tension bar so that the testing mechanism can add reagents into the testing mechanism.

[0012] Preferably, an external shaft is fixedly connected to the outer end face of the fixed shaft, the outer side of the external shaft is rotatably connected to the instrument, and an arc-shaped tooth is fixedly connected to the end of the external shaft away from the fixed shaft;

[0013] A gearbox is used to convert the deflection angle of the arc-shaped teeth into multiple circumferential rotations and to mesh with the arc-shaped teeth for transmission.

[0014] Preferably, the gears inside the gearbox are equipped with gear bushings, and an elastic strip is fixedly connected to the outer side of the gear bushing;

[0015] The closed door and the fixed shaft deflect outward within the support, and then through the meshing transmission of the arc-shaped teeth, the deflection of the fixed shaft is converted into multiple circumferential rotations of the gears inside the gearbox.

[0016] Preferably, the device under test includes a first limiting plate, which is fixedly connected to the bottom of the inner cavity of the instrument, and an arc-shaped sleeve is slidably adapted to the outer side of the first limiting plate, and a first magnetic block is fixedly connected to the outer side of the arc-shaped sleeve.

[0017] A first splitting tube is inserted into the inside of the arc-shaped frame, and an inner tube is fixedly installed inside the first splitting tube.

[0018] A mesh is used to store and treat the test reagents that have been fixed and dried by the freeze-dried reagents, and it is fixedly connected inside the first inner tube.

[0019] Preferably, a second splitting tube is inserted inside the arc-shaped frame, and a second inner tube is fixedly connected inside the second splitting tube;

[0020] The layering sheet is used to separate the reagent solution after the reaction into layers and is fixedly connected inside the second inner tube.

[0021] Preferably, the testing mechanism includes a vertical rail, which is fixedly connected to the inside of the instrument, and a sliding plate is fitted inside the vertical rail;

[0022] A reset spring is used to reset the slide plate and is fixedly connected to the top of the slide plate. The end of the reset spring away from the slide plate is fixedly connected to the top of the vertical rail cavity.

[0023] A hollow frame is fixedly connected to the outer side of the slide plate, and a reagent tube is fixedly installed on the top of the hollow frame. A sealing sleeve is inserted into the top of the reagent tube.

[0024] Preferably, the bottom of both the skateboard and the hollow frame is fitted with a sloping strip, one end of which is fixedly connected to the vertical rail, and the end of the sloping strip away from the vertical rail is pressed and fitted with a sloping panel.

[0025] A drawer frame is fixedly connected to the bottom end of the sloping panel, and the drawer frame is slidably adapted to the inside of the hollow frame. A side panel is fixedly connected to the outer side of the sloping panel, and a spring is fixedly connected to the outer side of the side panel. The end of the spring away from the side panel is fixedly connected to the inner side of the hollow frame.

[0026] Preferably, the discharge mechanism includes a transition hole, which is opened at the center of the instrument. A second magnetic block is fixedly connected to the end of the inner cavity of the instrument away from the first limiting plate, wherein the first magnetic block and the second magnetic block maintain an attractive relationship.

[0027] A discharge platform is fixedly installed on the outside of the instrument, and an insertion plate is inserted into the top of the discharge platform. A limit block is fixedly connected to the top of the insertion plate.

[0028] Preferably, a motor is fixedly installed at the bottom of the instrument, the output end of the motor is connected to a bushing plate via a coupling, a bottom connecting rod is fixedly connected to the top of the bushing plate, and a support ring plate is fixedly connected to the top of the bottom connecting rod. The support ring plate is slidably adapted to the bottom of the instrument and the discharge platform respectively.

[0029] The top of the ring plate is fixedly connected to a friction protrusion, and the inside of the instrument is fixedly connected to a second limiting plate.

[0030] Compared with the prior art, the beneficial effects of the present invention are:

[0031] 1. When the closed door deflects outward to the first predetermined angle, the device under test will automatically move to the position of the closed door, thereby placing the test tube into it and preparing for subsequent testing.

[0032] 2. As the drawer frame moves outward, the outlet at the bottom of the reagent tube opens, and the added reagent inside the reagent tube enters the No. 1 splitting tube and the No. 2 splitting tube respectively. This allows the testing mechanism to move downward and automatically add the added reagent into the test tube for reaction processing when the closed door deflects outward to the second predetermined angle.

[0033] 3. The mesh is used to store the test reagents that have been lyophilized and fixed. The lyophilized test reagents are separated from the lyophilized additives dispensed from the test tubes. The test reagents are in the mesh, while the lyophilized additives are in the test tube. This ensures that the lyophilized reagents are in a dry state with extremely low moisture content, effectively inhibiting chemical reactions caused by moisture and maintaining stable activity and performance of the reagents for a longer period of time.

[0034] 4. The layering sheet serves to separate the mixed solution of detection reagent and added reagent stored inside the No. 2 inner tube through reconstitution with a specific solution and initiation by an initiator, so that the added reagent can react with the different layers. After standing for a period of time, a chemiluminescence instrument is used to determine which layer reacts more strongly.

[0035] 5. When the closed door is closed, the entire device under test will return to the position corresponding to the revolving door, thus achieving the function of automatically resetting both the device under test and the testing mechanism when the closed door is closed. Attached Figure Description

[0036] Figure 1 This is a schematic diagram of the external structure of a 6-channel freeze-drying single-person chemiluminescence instrument according to the present invention.

[0037] Figure 2 This is a cross-sectional view of the overall structure of the present invention.

[0038] Figure 3 For the present invention Figure 2 A magnified structural diagram of point A in the middle.

[0039] Figure 4 This is a schematic diagram of the structure of some components in the overall device of the present invention.

[0040] Figure 5 This is a cross-sectional structural diagram of some components in the overall device of the present invention.

[0041] Figure 6 This is a schematic diagram of the structure of the mechanism to be tested in this invention.

[0042] Figure 7 This is a top view of the structure of the mechanism to be tested in this invention.

[0043] Figure 8 This is a schematic diagram of the structure of the first component of the mechanism to be tested according to the present invention.

[0044] Figure 9 This is a schematic diagram of the structure of the second component of the mechanism to be tested in this invention.

[0045] Figure 10 This is a schematic diagram of the testing mechanism of the present invention.

[0046] Figure 11 This is a cross-sectional structural diagram of the testing mechanism of the present invention.

[0047] Figure 12 This is a schematic diagram of the material discharge mechanism of the present invention.

[0048] Figure 13 This is a bottom view of the material discharge mechanism of the present invention.

[0049] Figure 14 This is a schematic diagram of the test structure of the material discharge mechanism of the present invention.

[0050] Figure 15 This is a cross-sectional view of the material discharge mechanism of the present invention.

[0051] In the diagram: 1. Instrument and equipment; 2. Revolving door; 3. Mechanism to be tested; 4. Testing mechanism; 5. Discharge mechanism; 6. Support; 7. Fixed shaft; 8. Closed door; 9. Tension bar; 10. External shaft; 11. Arc-shaped tooth; 12. Gearbox; 13. Elastic bar; 31. First limiting plate; 32. Arc-shaped sleeve; 33. Magnetic block No. 1; 34. Splitting tube No. 1; 35. Inner tube No. 1; 36. Net; 37. Splitting tube No. 2; 38. Inner tube No. 2; 39. 41. Sheet; 42. Vertical rail; 43. Return spring; 44. Slide plate; 45. Hollow frame; 46. Reagent tube; 47. Sealing sleeve; 48. Slanted nipple; 49. Slanted panel; 40. Drawer frame; 41. Side panel; 401. Spring; 51. Transition hole; 52. No. 2 magnetic block; 53. Second limiting plate; 54. Support ring plate; 55. Friction protrusion; 56. Bottom connecting rod; 57. Bushing plate; 58. Motor; 59. Discharge platform; 50. Insertion plate; 501. Limiting block. Detailed Implementation

[0052] The present invention will now be further described with reference to the accompanying drawings and specific embodiments. It should be noted that, without conflict, the various embodiments or technical features described below can be arbitrarily combined to form new embodiments. It should be understood that the described embodiments are merely some embodiments of the present invention, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are within the scope of protection of the present invention.

[0053] Please see Figures 1 to 15 The present invention provides a technical solution: such as Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, it includes an instrument 1 for chemiluminescence detection of detection reagents and additive reagents, and a rotating door 2 is connected to the outside of the instrument 1 by a hinge.

[0054] The test unit 3 is used to store the test reagents that have been fixed and dried by freeze-drying. The test unit 3 is located inside the instrument 1.

[0055] Test mechanism 4 is used for storing and treating the added reagents after freeze-drying. Test mechanism 4 is located inside instrument 1.

[0056] The discharge mechanism 5 is used to remove the mixed substance after the chemical emission detection is completed. The discharge mechanism 5 is located inside the instrument 1.

[0057] A support 6 is fixedly connected to the outside of the instrument 1, a fixed shaft 7 is rotatably connected inside the support 6, and a closed door 8 is fixedly installed on the outside of the fixed shaft 7.

[0058] A tension strip 9 is fixedly connected to the outer end face of the closed door 8. The end of the tension strip 9 away from the closed door 8 is connected to the testing mechanism 4. The tension strip 9 passes through the outside of the instrument 1 and extends into its interior.

[0059] The closed door 8 and the fixed shaft 7 deflect outward within the support 6, and the force is transmitted through the tension bar 9 so that the testing mechanism 4 will add the reagent into the testing mechanism 3.

[0060] An external shaft 10 is fixedly connected to the outer end face of the fixed shaft 7. The outer side of the external shaft 10 is rotatably connected to the instrument 1. An arc-shaped tooth 11 is fixedly connected to the end of the external shaft 10 away from the fixed shaft 7.

[0061] The gearbox 12 is used to convert the deflection angle of the arc-shaped teeth 11 into multiple circumferential rotations and to mesh with the arc-shaped teeth 11 for transmission.

[0062] The gears inside the gearbox 12 are equipped with gear bushings, and the outer side of the gear bushings is fixedly connected to a spring strip 13. The closing door 8 is fixedly connected to the fixed shaft 7. Therefore, when the operator pulls the closing door 8 outward, it causes the fixed shaft 7 to deflect outward around the support 6. The outer end face of the fixed shaft 7 is fixedly connected to the external shaft 10. Therefore, the arc-shaped teeth 11 connected to the other end of the external shaft 10 will deflect counterclockwise. The arc-shaped teeth 11 are connected to the gearbox 12... The gears in the gearbox 12 mesh with each other and drive the transmission. There are only two gears in the gearbox 12, a large gear and a small gear mesh with each other. The large gear meshes with the arc-shaped teeth 11, and the gear bushing on the small gear is fixedly connected to the elastic strip 13. The outer side of the gear bushing is patterned, which increases the friction between the elastic strip 13 and the gear bushing and prevents the elastic strip 13 from falling off. In addition, the gearbox 12 converts the small angle of deflection of the arc-shaped teeth 11 into multiple circular rotations.

[0063] The closed door 8 and the fixed shaft 7 deflect outward within the support 6, and then through the meshing transmission of the arc-shaped teeth 11, the deflection of the fixed shaft 7 is converted into multiple circumferential rotations of the gears inside the gearbox 12.

[0064] like Figure 6 , Figure 7 , Figure 8 , Figure 9 , Figure 10 and Figure 11 As shown, the device under test 3 includes a first limiting plate 31, which is fixedly connected to the bottom of the inner cavity of the instrument 1. An arc-shaped sleeve 32 is slidably adapted to the outer side of the first limiting plate 31, and a first magnetic block 33 is fixedly connected to the outer side of the arc-shaped sleeve 32.

[0065] A first split tube 34 is inserted into the inside of the arc-shaped sleeve 32, and a first inner tube 35 is fixedly installed inside the first split tube 34.

[0066] The mesh 36 is used to store the freeze-dried reagent and is fixedly connected inside the first inner tube 35. The first split tube 34 is also fixedly connected to the first inner tube 35, and the mesh 36 is fixedly connected inside the first inner tube 35. The mesh 36 stores the freeze-dried reagent, which is separated from the freeze-dried reagent added from the reagent tube 45. The reagent is in the mesh 36, while the freeze-dried reagent is in the first test tube 35. In this state, neither reacts with the added reagent, ensuring the freeze-dried reagent remains in a dry state with extremely low moisture content. This effectively inhibits chemical reactions caused by moisture, such as hydrolysis and oxidation, reducing the degradation of bioactive components like proteins and nucleic acids, and allowing the reagent to maintain stable activity and performance over a longer period.

[0067] Furthermore, the 36-cell resonator separates the lyophilized detection reagent and the lyophilized additive reagent, and then reconstitutes them using a specific solution, along with mixing the initiator. This allows for comparison with the detection results in the second split tube 37, determining which detection method is more effective. It also helps prevent premature reactions between the lyophilized detection reagent and the additive reagent. The specific solution is phosphate buffered saline (PBS): composed of sodium dihydrogen phosphate and disodium hydrogen phosphate, it has good buffering capacity, maintaining the pH of the reconstituted solution within a relatively stable range. Suitable for various biological detection reagents, it ensures the activity and stability of the bioactive components in the reagents and enables the reconstitution of both the lyophilized detection reagent and the lyophilized additive reagent.

[0068] The arc-shaped frame 32 has a second splitting tube 37 inserted inside, and the second splitting tube 37 has a second inner tube 38 fixedly connected inside. The rotation of the gear bushing caused by the small gear causes the elastic strip 13 fixedly connected to the gear bushing to retract and pull the arc-shaped frame 32, thus pulling the arc-shaped frame 32 from the position of the rotating door 2 to the position of the closed door 8. At this time, the operator can insert the first splitting tube 34 and the second splitting tube 37 into the arc-shaped frame 32 respectively, so that when the closed door 8 deflects outward to the first predetermined angle, the test mechanism 3 will automatically move to the position of the closed door 8 and put the test tube into it.

[0069] Some tumor marker detection reagents are also made in lyophilized form, such as alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA). These are detection reagents. By lyophilizing the specific antibodies or antigens targeting these tumor markers, the reagents are reconstituted before use, and an initiator is added to induce an immune reaction with the tumor markers (additional reagents) in the sample. The level of the tumor markers (analytes) is then detected by chemiluminescence signal, which helps in the early detection, diagnosis, and treatment monitoring of tumors.

[0070] The layering sheet 39 is used to separate the reagent solution after the reaction and is fixedly connected inside the second inner tube 38. The second splitting tube 37 is fixedly connected to the second inner tube 38, and the second inner tube 38 is fixedly connected to several layering sheets 39. The layering sheet 39 separates the mixed solution of the detection reagent and added reagent, which has been reconstituted with a specific solution and initiated by an initiator, stored inside the second inner tube 38. This facilitates the reaction of the added reagent with its different layers. After a period of stillness, a chemiluminescence instrument is used to determine which layer reacts more strongly. Simultaneously, the luminescent signal adheres to the layering sheet 39, making it easier to determine the content of the analyte.

[0071] The testing mechanism 4 includes a vertical rail 41, which is fixedly connected to the inside of the instrument 1, and a sliding plate 43 is fitted inside the vertical rail 41.

[0072] The reset spring 42 is used to reset the slide plate 43 and is fixedly connected to the top of the slide plate 43. The end of the reset spring 42 away from the slide plate 43 is fixedly connected to the top of the inner cavity of the vertical rail 41.

[0073] A hollow frame 44 is fixedly connected to the outside of the slide plate 43, a reagent tube 45 is fixedly installed on the top of the hollow frame 44, and a sealing sleeve 46 is inserted into the top of the reagent tube 45.

[0074] Both the bottom of the slide plate 43 and the hollow frame 44 are fitted with inclined plates 47. One end of the inclined plate 47 is fixedly connected to the vertical rail 41, and the end of the inclined plate 47 away from the vertical rail 41 is pressed against the inclined panel 48. When the operator continues to pull the closed door 8 outward, the arc-shaped frame 32 has reached the rightmost end of the inner cavity of the instrument 1, and the elastic strip 13 will stretch and lengthen accordingly. The tension strip 9, which is fixedly connected to the outer end of the closed door 8, will be pulled and tightened. The closed door 8 is opened when... When the deflection begins, the tension bar 9 is still in a relaxed and bent state. The other end of the tension bar 9 is connected to the hollow frame 44, and the hollow frame 44 is slidably fitted inside the vertical rail 41 by the slide plate 43. Therefore, the hollow frame 44, which is pulled by the tension bar 9, will move downward. The top of the hollow frame 44 is fixedly connected to the reagent tube 45, and the reagent tube 45 contains the added reagent. In addition, the sealing sleeve 46 can be pulled out from the top of the reagent tube 45 to replenish the added reagent inside.

[0075] A drawer frame 49 is fixedly connected to the bottom of the slanted panel 48. The drawer frame 49 slides inside the hollow frame 44. A side panel 40 is fixedly connected to the outside of the slanted panel 48. A spring 401 is fixedly connected to the outside of the side panel 40. The end of the spring 401 away from the side panel 40 is fixedly connected to the inside of the hollow frame 44. When the slide plate 43 moves downward with the hollow frame 44, the inclined panel 48 inside the hollow frame 44 is squeezed by the inclined nipple 47, which is fixedly connected to the bottom of the inner cavity of the vertical rail 41. The bottom of the inclined panel 48 is fixedly connected to the drawer frame 49, and the drawer frame 49 slides inside the hollow frame 44. Therefore, the inclined panel 48, squeezed by the inclined nipple 47, will pull the drawer frame 49 out of the hollow frame 44. The bottom of the inner cavity of the drawer frame 49 blocks the discharge port at the bottom of the reagent tube 45. However, as the drawer frame 49 moves outward, the discharge port at the bottom of the reagent tube 45 will open. Finally, the added reagent inside the reagent tube 45 will enter the first splitting tube 34 and the second splitting tube 37 respectively. This achieves the function of the testing mechanism 4 moving downward and automatically adding the added reagent into the test tube for reaction when the closed door 8 deflects outward to the second predetermined angle.

[0076] The reaction between the aforementioned detection reagent and the added reagent is initiated by the addition of an initiator, which causes the reaction system to emit chemiluminescence. The initiator is added along with a specific solution.

[0077] like Figure 12 , Figure 13 , Figure 14 and Figure 15 As shown, the discharge mechanism 5 includes a transition hole 51, which is located at the center of the instrument 1. A second magnetic block 52 is fixedly connected to the end of the inner cavity of the instrument 1 away from the first limiting plate 31. The first magnetic block 33 and the second magnetic block 52 maintain an attraction relationship. When the reagent is added into the two split tubes, the sealing door 8 is closed. At this time, under the action of the reset spring 42 and the spring 401, the hollow frame 44 is reset and moved upward, while the drawer frame 49 is reset and stored in the hollow frame 44, and the discharge port at the bottom of the reagent tube 45 is resealed. At the same time, the clockwise closing of the closed door 8 causes the elastic strip 13 to loosen the gear bushing on the pinion in the opposite direction. A first magnetic block 33 is fixedly connected to the outer side of the arc-shaped frame 32, and a second magnetic block 52 is fixedly connected to the left end of the inner cavity of the instrument 1. Therefore, under the attraction between the two magnetic blocks, and when the closed door 8 is closed, the entire test mechanism 3 will return to the position corresponding to the rotating door 2 for processing, thus achieving the function of automatically resetting both the test mechanism 3 and the testing mechanism 4 when the closed door 8 is closed.

[0078] An output platform 59 is fixedly installed on the outside of the instrument 1. An insertion plate 50 is inserted into the top of the output platform 59. A limit block 501 is fixedly connected to the top of the insertion plate 50.

[0079] When the sealing door 8 is closed, the test device 3 will move directly above the support plate 54. At this time, an appropriate amount of specific solution is added, and the lyophilized reagent can be quickly dissolved and restored to its original solution state. It can react with the test reagent immediately. The operation is simple and fast, which can meet the needs of rapid on-site detection. It also prevents the two from reacting too early, thus missing the best detection time. Finally, the chemiluminescence instrument will detect and process the mixed solution of the two.

[0080] A motor 58 is fixedly installed at the bottom of the instrument 1. The output end of the motor 58 is connected to a bushing plate 57 through a coupling. A bottom connecting rod 56 is fixedly connected to the top of the bushing plate 57. A support ring plate 54 is fixedly connected to the top of the bottom connecting rod 56. The support ring plate 54 is slidably adapted to the bottom of the instrument 1 and the discharge platform 59 respectively.

[0081] The top of the support ring plate 54 is fixedly connected to a friction protrusion 55, and the inside of the instrument 1 is fixedly connected to a second limiting plate 53. After the test is completed, the motor 58 is started, which causes the bushing plate 57 connected to its output end via a coupling to rotate clockwise. This rotation is judged from a top-down perspective. The other end of the bushing plate 57 is connected to the support ring plate 54 via a bottom connecting rod 56. In addition, the top of the support ring plate 54 is fixedly connected to a friction protrusion 55, which increases the friction between the support ring plate 54 and the instrument under test 3. Therefore, the support ring plate 54 will rotate clockwise with the instrument under test 3 until it moves into the discharge platform 59. Then the operator pulls the insert plate 50 out from the top of the discharge platform 59 and then pulls out the instrument under test 3.

[0082] In use, the closed door 8 is fixedly connected to the fixed shaft 7. Therefore, when the operator pulls the closed door 8 outward, it causes the fixed shaft 7 to deflect outward around the support 6. The outer end face of the fixed shaft 7 is fixedly connected to the external shaft 10. Therefore, the arc-shaped tooth 11 connected to the other end of the external shaft 10 will deflect counterclockwise. The arc-shaped tooth 11 meshes with the gears inside the gearbox 12, and the gearbox 12 contains only two gears, one large and one small. The gear and a small gear mesh with each other for transmission, while the large gear meshes with the arc-shaped teeth 11 for transmission. The gear bushing on the small gear is fixedly connected to the elastic strip 13. Therefore, the rotation of the gear bushing caused by the small gear causes the elastic strip 13 fixedly connected to the gear bushing to retract and pull the arc-shaped frame 32, causing the arc-shaped frame 32 to be pulled from the position of the revolving door 2 to the position of the closed door 8. At this time, the operator can insert the first split tube 34 and the second split tube 37 into the arc-shaped frame 32 respectively.

[0083] As the operator continues to pull the closed door 8 outward, the arc-shaped frame 32 has reached the rightmost end of the inner cavity of the instrument 1, and the elastic strip 13 will stretch and lengthen accordingly. The tension strip 9, which is fixedly connected to the outer end of the closed door 8, will be pulled and tightened. When the closed door 8 initially deflects, the tension strip 9 is still in a relaxed and bent state. The other end of the tension strip 9 is connected to the hollow frame 44, and the hollow frame 44 is slidably adapted to the inside of the vertical rail 41 by the slide plate 43. Therefore, the hollow frame 44, pulled by the tension strip 9, will move downward. The top of the hollow frame 44 is fixedly connected to the reagent tube 45, and the reagent tube 45 contains the added reagent. In addition, the closed sleeve 46 can be pulled out from the top of the reagent tube 45 to replenish the added reagent inside. When the slide plate 43 moves downward with the hollow frame 44, the inclined panel 48 inside the hollow frame 44 is squeezed by the inclined nipple 47, which is fixedly connected to the bottom of the inner cavity of the vertical rail 41. The bottom of the inclined panel 48 is fixedly connected to the drawer frame 49, and the drawer frame 49 slides inside the hollow frame 44. Therefore, the inclined panel 48, squeezed by the inclined nipple 47, will pull the drawer frame 49 out of the hollow frame 44. The bottom of the inner cavity of the drawer frame 49 blocks the discharge port at the bottom of the reagent tube 45. However, as the drawer frame 49 moves outward, the discharge port at the bottom of the reagent tube 45 will open, and the reagent added inside the reagent tube 45 will enter the first splitting tube 34 and the second splitting tube 37 respectively.

[0084] When reagents are added into the two split tubes, the sealing door 8 is closed. At this time, under the action of the return spring 42 and the spring 401, the hollow frame 44 is reset and moved upward, while the drawer frame 49 is reset and stored inside the hollow frame 44, and the discharge port at the bottom of the reagent tube 45 is resealed. At the same time, the clockwise closing of the sealing door 8 causes the elastic strip 13 to loosen the gear bushing on the pinion in the opposite direction. The outer side of the arc-shaped sleeve 32 is fixedly connected to a first magnetic block 33, and the left end of the inner cavity of the instrument 1 is fixedly connected to a second magnetic block 52. Therefore, under the attraction between the two magnetic blocks, and when the sealing door 8 is closed, the entire test mechanism 3 will return to the position corresponding to the rotating door 2.

[0085] After the test is completed, the motor 58 is started, which causes the bushing plate 57 connected to its output end via a coupling to rotate clockwise. This rotation is judged from a top-down perspective. The other end of the bushing plate 57 is connected to the support ring plate 54 via the bottom connecting rod 56. In addition, the top of the support ring plate 54 is fixedly connected with a friction protrusion 55, which increases the friction between the support ring plate 54 and the instrument under test 3. Therefore, the support ring plate 54 will rotate clockwise with the instrument under test 3 until it moves into the discharge platform 59. Then the operator pulls the insertion plate 50 out from the top of the discharge platform 59 and then pulls out the instrument under test 3.

[0086] The above embodiments are merely preferred embodiments of the present invention and should not be construed as limiting the scope of protection of the present invention. Any modifications made by those skilled in the art based on the above concepts without creative effort shall fall within the scope of protection of the present invention.

Claims

1. A 6-channel freeze-drying single-dose chemiluminescence instrument, characterized in that, include: An instrument (1) for chemiluminescence detection of detection reagents and additive reagents, wherein a rotating door (2) is connected to the outside of the instrument (1) by a hinge. The test device (3) is used for storing test reagents that have been fixed and dried by freeze drying, and the test device (3) is disposed inside the instrument (1); The testing mechanism (4) is used for storing and treating the added reagents after freeze-drying, and the testing mechanism (4) is located inside the instrument (1); The discharge mechanism (5) is used to remove the mixed substance after chemiluminescence detection is completed. The discharge mechanism (5) is located inside the instrument (1). The instrument (1) is fixedly connected to a support (6) on the outside, and a fixed shaft (7) is rotatably connected inside the support (6). A closed door (8) is fixedly installed on the outside of the fixed shaft (7). A tension strip (9) is fixedly connected to the outer end face of the closed door (8). The end of the tension strip (9) away from the closed door (8) is connected to the testing mechanism (4). The tension strip (9) passes through the outside of the instrument (1) and extends into its interior. The closed door (8) and the fixed shaft (7) deflect outward within the support (6), and the force is transmitted through the tension bar (9) so that the testing mechanism (4) will add the reagent into the testing mechanism (3). An external shaft (10) is fixedly connected to the outer end face of the fixed shaft (7). The outer side of the external shaft (10) is rotatably connected to the instrument (1). An arc-shaped tooth (11) is fixedly connected to the end of the external shaft (10) away from the fixed shaft (7). Gearbox (12) is used to convert the deflection angle of the arc-shaped teeth (11) into multiple circumferential rotations and to mesh with the arc-shaped teeth (11) for transmission. The gear inside the gearbox (12) is equipped with a gear bushing, and an elastic strip (13) is fixedly connected to the outside of the gear bushing. The closed door (8) and the fixed shaft (7) deflect outward within the support (6), and then through the meshing transmission of the arc-shaped teeth (11), the deflection of the fixed shaft (7) is converted into multiple circumferential rotations of the gear inside the gearbox (12).

2. The 6-channel freeze-drying single-person chemiluminescence instrument according to claim 1, characterized in that: The test mechanism (3) includes a first limiting plate (31), which is fixedly connected to the bottom of the inner cavity of the instrument (1). An arc-shaped sleeve (32) is slidably adapted to the outer side of the first limiting plate (31), and a first magnetic block (33) is fixedly connected to the outer side of the arc-shaped sleeve (32).

3. The 6-channel freeze-drying single-person chemiluminescence instrument according to claim 2, characterized in that: A first split tube (34) is inserted into the inside of the arc-shaped sleeve (32), and a first inner tube (35) is fixedly installed inside the first split tube (34). The mesh (36) is used to store the test reagents that have been fixed and dried by the freeze-dried reagents, and is fixedly connected inside the first inner tube (35).

4. A 6-channel freeze-drying single-person chemiluminescence instrument according to claim 2, characterized in that: The arc-shaped sleeve (32) is internally connected to a second split tube (37), and the second split tube (37) is internally fixedly connected to a second inner tube (38). The layering sheet (39) is used to layer the reagent solution after the reaction and is fixedly connected inside the second inner tube (38).

5. A 6-channel freeze-drying single-person chemiluminescence instrument according to claim 1, characterized in that: The testing mechanism (4) includes a vertical rail (41), which is fixedly connected to the inside of the instrument (1), and the inside of the vertical rail (41) is fitted with a sliding plate (43). A reset spring (42) is used to reset the slide plate (43) and is fixedly connected to the top of the slide plate (43). The end of the reset spring (42) away from the slide plate (43) is fixedly connected to the top of the inner cavity of the vertical rail (41). A hollow frame (44) is fixedly connected to the outside of the slide plate (43), and a reagent tube (45) is fixedly installed on the top of the hollow frame (44). A sealing sleeve (46) is inserted into the top of the reagent tube (45).

6. A 6-channel freeze-drying single-person chemiluminescence instrument according to claim 5, characterized in that: The bottom of the slide (43) and the hollow frame (44) are fitted with inclined strips (47), one end of the inclined strips (47) is fixedly connected to the vertical rail (41), and the end of the inclined strips (47) away from the vertical rail (41) is pressed and fitted with an inclined panel (48).

7. A 6-channel freeze-drying single-person chemiluminescence instrument according to claim 6, characterized in that: A drawer frame (49) is fixedly connected to the bottom end of the sloping panel (48). The drawer frame (49) is slidably adapted to the inside of the hollow frame (44). A side plate (40) is fixedly connected to the outside of the sloping panel (48). A spring (401) is fixedly connected to the outside of the side plate (40). One end of the spring (401) away from the side plate (40) is fixedly connected to the inside of the hollow frame (44).

8. A 6-channel freeze-drying single-person chemiluminescence instrument according to claim 1, characterized in that: The discharge mechanism (5) includes a transition hole (51), which is located at the center of the instrument (1). A second magnetic block (52) is fixedly connected to one end of the inner cavity of the instrument (1) away from the first limiting plate (31), wherein the first magnetic block (33) and the second magnetic block (52) maintain an attraction relationship. A discharge platform (59) is fixedly installed on the outside of the instrument (1). A through plate (50) is inserted into the top of the discharge platform (59). A limit block (501) is fixedly connected to the top of the through plate (50).

9. A 6-channel freeze-drying single-person chemiluminescence instrument according to claim 8, characterized in that: A motor (58) is fixedly installed at the bottom of the instrument (1). The output end of the motor (58) is connected to a bushing plate (57) via a coupling. A bottom connecting rod (56) is fixedly connected to the top of the bushing plate (57). A support ring plate (54) is fixedly connected to the top of the bottom connecting rod (56). The support ring plate (54) is slidably adapted to the bottom of the instrument (1) and the discharge platform (59). The top of the ring plate (54) is fixedly connected to a friction protrusion (55), and the inside of the instrument (1) is fixedly connected to a second limiting plate (53).

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