Biosafety experiment cabinet with adjustable airtight degree

By designing adjustable transparent partitions and glove operating windows in the biosafety cabinet, combined with airflow channels and filtration systems, the problem that existing biosafety cabinets cannot take into account different air density is solved, and flexible switching of airtight effects in the cabinet is achieved, improving the flexibility and safety of experimental operations.

CN120550872APending Publication Date: 2025-08-29CHINESE PEOPLES LIBERATION ARMY NAVAL SPECIALTY MEDICAL CENT
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Patent Information

Application Number
CN202510631719.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-05-16
Publication Date
2025-08-29

AI Technical Summary

Technical Problem

The existing biosafety cabinet lacks an experimental operation that can take into account different air density to meet different usage needs.

Method used

A biosafety experimental cabinet with adjustable airtightness is designed. By lifting and lowering transparent partitions and detachable transparent windows or glove operating windows, combined with airflow channels and filtration systems, the airtight effect in the cabinet is switched.

Benefits of technology

It realizes flexible adjustment of the degree of isolation between inside and outside the biosafety cabinet, and switches to meet different airtightness requirements, improving the flexibility and safety of experimental operations.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a biological safety experiment cabinet with an adjustable airtight degree. A biological safety experiment cabinet with the adjustable airtight degree comprises a biological safety cabinet body, the biological safety cabinet body comprises a cabinet body, an operation table and a transparent partition plate arranged on the front portion of the cabinet body in a lifting and sliding mode, two operation openings are formed in the transparent partition plate in a left-right mode, and mounting flange plates are fixed to the outer sides of the operation openings; the mounting flange plate is detachably connected with a transparent window or a glove operation window; the glove operation window comprises a glove and a glove fixing flange plate used for fixing a glove opening of the glove, and the glove fixing flange plate is detachably connected with the mounting flange plate; an upper working position and a lower working position which are arranged up and down are arranged in the lifting process of the transparent partition plate; when the transparent partition plate is located at the upper working position, an operation space for containing hands is formed between the transparent partition plate and the operation table; when the transparent partition plate is located at the lower working position, the transparent partition plate abuts against the limiting groove. According to the invention, switching of experiment conditions of different airtight effects in the cabinet body is realized.
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Description

Technical Field

[0001] The present invention relates to the technical field of experimental equipment, in particular to a biosafety experimental cabinet. Background Art

[0002] A biological safety cabinet is a device often used when preparing chemotherapy drugs or other toxic drugs. It uses ventilation devices to force exhaust to expel harmful substances that are released into the air during preparation.

[0003] Existing biosafety cabinets have a transparent partition installed at the front, allowing the operator to operate through an operating window formed between the transparent partition and the operating table. For example, Publication No. CN101983772A discloses a biosafety cabinet with comfortable operation. Of course, there are also biosafety cabinets with glove ports installed at the front, allowing operators to perform laboratory operations through the glove ports. For example, Publication No. CN101862688A discloses a Class III biosafety cabinet.

[0004] The above two biosafety cabinets achieve two different air densities. Currently, there is a lack of a biosafety cabinet that can take into account the above two different air densities to meet different usage requirements. Summary of the Invention

[0005] In view of the problems and shortcomings of the prior art, the present invention provides a biosafety laboratory cabinet with adjustable airtightness.

[0006] The present invention solves the above technical problems through the following technical solutions:

[0007] The present invention provides a biosafety laboratory cabinet with adjustable airtightness, comprising a biosafety cabinet body, the biosafety cabinet body comprising a cabinet body, an operating table, and a transparent partition at the front of the cabinet body that is arranged to be lifted and slidable. The transparent partition is characterized in that two operating ports arranged on the left and right are formed on the transparent partition, and a mounting flange is fixed to the outer side of the operating port;

[0008] The mounting flange is detachably connected to a transparent window or a glove operation window;

[0009] The glove operation window includes a glove and a glove fixing flange for fixing the glove cuff, and the glove fixing flange is detachably connected to the mounting flange;

[0010] The transparent partition is provided with an upper working position and a lower working position arranged up and down during the lifting process;

[0011] An air flow channel is provided on the transparent partition, the top of the air flow channel is connected to the air outlet of an air inlet fan, a strip opening is provided on the lower side of the transparent partition and is connected to the air flow channel, the strip opening is used to guide the isolation air curtain, a limiting groove is provided on the operating table for embedding the transparent partition, and the bottom of the limiting groove is connected to an exhaust pipe connected to the strip opening;

[0012] When the transparent partition is in the upper working position, there is an operating space for accommodating hands between the transparent partition and the operating table;

[0013] When the transparent partition is in the lower working position, the transparent partition abuts against the limiting groove, the strip opening faces the exhaust pipe, and a gap exists between the strip opening and the exhaust pipe. The isolation air curtain serves as an internal and external isolation barrier at the gap.

[0014] The present invention realizes the switching of experimental conditions with different airtight effects in the cabinet.

[0015] Further preferably, a first air inlet hole group is opened on the front side of the operating table, and a second air inlet hole group is opened on the rear side of the operating table;

[0016] When the transparent partition is lowered to abut against the operating table, the cabinet and the transparent partition form an operating room, and the first air inlet hole group and the second air inlet hole group are located in the operating room;

[0017] An air inlet channel and an air exhaust channel are provided in the cabinet;

[0018] A first HEPA filter module and an exhaust fan are sequentially installed in the exhaust channel;

[0019] The air inlet fan and the second HEPA filter module are installed in the air inlet channel from top to bottom;

[0020] The air inlet channel is located below the second HEPA filter module and has a branch channel, and the branch channel is connected to the air flow channel through a bellows;

[0021] A valve is provided on the branch channel;

[0022] When the transparent partition is in the upper working position, the valve is closed;

[0023] When the transparent partition is in the lower working position, the valve is opened.

[0024] Further preferably, transfer windows are installed on the left and right side walls of the cabinet, and the transfer window includes a transfer room, and switch windows are installed on the left and right sides of the transfer room.

[0025] Further preferably, a storage cabinet for storing the transparent window and the glove operation window is installed at the bottom of the cabinet;

[0026] The storage cabinet is provided with an upper sliding drawer plate and a lower sliding drawer plate arranged up and down;

[0027] The upper sliding drawer is used to place the transparent window;

[0028] The lower sliding drawer plate is used to place the glove fixing flange;

[0029] The upper sliding drawer plate and the lower sliding drawer plate are both provided with a U-shaped notch; and the outer edge of the U-shaped notch is provided with a lap groove for sliding a component in transversely.

[0030] It is convenient to store components. According to different usage requirements, you can switch between installing a transparent window and a glove operation window.

[0031] Further preferably, an ultraviolet germicidal lamp is installed on the top and bottom of the storage cabinet.

[0032] Convenient for UV sterilization.

[0033] Further preferably, a cabinet door is installed on the front side of the storage cabinet, and a control switch for controlling the opening and closing of the ultraviolet germicidal lamp is installed on the cabinet door, and the control switch is located on the connection line between the power supply and the ultraviolet germicidal lamp.

[0034] Further preferably, an air flow channel is provided on the left and right sides of the transparent partition;

[0035] Air intake pipes with upward openings are fixed on the left and right sides of the cabinet body. The air intake pipes are located below the second HEPA filter module. The air intake pipes are connected to the bellows through an extension pipe that is horizontally arranged and extends out of the cabinet body. The bellows is connected to the air flow channel.

[0036] Further preferably, the inner wall of the mounting flange is an outward-expanding hole structure, a blind hole is opened on the mounting flange, and the inner wall of the blind hole is provided with an internal thread.

[0037] Further preferably, the glove fixing flange comprises a first sealing portion, a first radially extending mounting portion and a glove mounting portion sequentially connected along the axial direction;

[0038] The first sealing portion, the first radially extending mounting portion, and the glove mounting portion are all provided with through holes that are interconnected;

[0039] The outer diameter of the first radially extending mounting portion is greater than the outer diameter of the first sealing portion, and a mounting hole is formed on the first radially extending mounting portion;

[0040] The outer diameter of the first sealing portion increases gradually along the axial direction toward the first radially extending mounting portion;

[0041] A first sealing ring is fixed on the outer wall of the first sealing portion, and the first sealing ring is used to be sandwiched between the first sealing portion and the hole expansion structure;

[0042] The cuff of the glove is sleeved on the outside of the glove mounting portion and is fixed by an elastic ring.

[0043] Further preferably, the transparent window comprises a second sealing portion and a second radially extending mounting portion sequentially connected along the axial direction;

[0044] The outer diameter of the second radially extending mounting portion is greater than the outer diameter of the second sealing portion, and a mounting hole is formed on the second radially extending mounting portion;

[0045] The outer diameter of the second sealing portion increases axially toward the second radially extending mounting portion;

[0046] A second sealing ring is fixed on the outer wall of the second sealing portion; the second sealing ring is used to be sandwiched between the second sealing portion and the hole expansion structure.

[0047] On the basis of conforming to the common sense in this field, the above-mentioned preferred conditions can be arbitrarily combined to obtain the preferred embodiments of the present invention.

[0048] The positive progress effect of the present invention is:

[0049] The present invention realizes the switching adjustment of the isolation degree between the inside and outside of the biosafety experiment cabinet, and meets the switching of different air tightness requirements inside the cabinet. BRIEF DESCRIPTION OF THE DRAWINGS

[0050] Figure 1 This is a structural diagram of a glove fixing flange installed in specific embodiment 1 of the present invention;

[0051] Figure 2 This is a schematic diagram of the internal airflow of a specific embodiment 1 of the present invention;

[0052] Figure 3 Schematic diagram of a transparent baffle in specific embodiment 1 of the present invention;

[0053] Figure 4 Schematic diagram of a transparent window according to a first embodiment of the present invention;

[0054] Figure 5 This is a schematic diagram of a glove-operated window assembly according to a specific embodiment 1 of the present invention;

[0055] Figure 6 This is a schematic diagram of a transparent baffle and a transparent window in combination according to a specific embodiment 1 of the present invention;

[0056] Figure 7 This is a schematic diagram of a combination of a transparent baffle and a glove operation window according to a specific embodiment 1 of the present invention;

[0057] Figure 8 A cross-sectional view of a storage cabinet according to a second specific embodiment of the present invention;

[0058] Figure 9 This is a structural schematic diagram of the lower sliding drawer of specific embodiment 2 of the present invention. DETAILED DESCRIPTION

[0059] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts shall fall within the scope of protection of the present invention.

[0060] like Figures 1 to 7 As shown in the specific embodiment 1, a biosafety laboratory cabinet with adjustable airtightness includes a biosafety cabinet body, the biosafety cabinet body includes a cabinet body, an operating table and a transparent partition 1 at the front of the cabinet body that is arranged to slide and lift. The transparent partition 1 is provided with two operating ports arranged on the left and right, and a mounting flange 11 is fixed to the outside of the operating port; the mounting flange 11 is detachably connected to a transparent window 2 or a glove operation window; the glove operation window includes a glove and a glove fixing flange 3 for fixing the opening of the glove 31, and the glove fixing flange 3 is detachably connected to the mounting flange; during the lifting process of the transparent partition 1, an upper working position and a lower working position arranged up and down are provided. The transparent partition 1 is provided with an air flow channel, the top of the air flow channel is connected to the air outlet of an air inlet fan, the lower side of the transparent partition 1 is provided with a strip opening 13 connected to the air flow channel, the strip opening 13 is used to guide the isolation air curtain, and the operating table is provided with a limiting groove for embedding the transparent partition 1, and the bottom of the limiting groove is connected to the exhaust pipe 73 connected to the strip opening 13; when the transparent partition 1 is in the upper working position, there is an operating space for accommodating hands between the transparent partition 1 and the operating table; when the transparent partition 1 is in the lower working position, the transparent partition 1 is against the limiting groove, and the strip opening 13 is opposite to the exhaust pipe 73, and there is a gap between the strip opening 13 and the exhaust pipe 73. The isolation air curtain serves as an internal and external isolation barrier at the gap. The present invention realizes the switching of experimental conditions with different airtight effects in the cabinet.

[0061] The exhaust pipe is an L-shaped exhaust pipe, and the outlet direction of the exhaust pipe 73 faces the exhaust channel.

[0062] The inner wall of the mounting flange is an outward-expanding hole structure. A blind hole is opened on the mounting flange, and an inner wall of the blind hole is provided with an internal thread.

[0063] The glove fixing flange 3 includes a first sealing portion, a first radially extending mounting portion and a glove mounting portion connected in sequence along the axial direction; the first sealing portion, the first radially extending mounting portion and the glove mounting portion are all provided with through holes that are connected to each other; the outer diameter of the first radially extending mounting portion is larger than the outer diameter of the first sealing portion, and a mounting hole is provided on the first radially extending mounting portion; the outer diameter of the first sealing portion increases gradually along the axial direction toward the side of the first radially extending mounting portion; a first sealing ring is fixed on the outer wall of the first sealing portion, and the first sealing ring is used to be clamped between the first sealing portion and the reaming structure; the glove cuff is sleeved on the outside of the glove mounting portion and fixed by an elastic ring.

[0064] The transparent window 2 includes a second sealing portion and a second radially extending mounting portion connected in sequence along the axial direction; the outer diameter of the second radially extending mounting portion is larger than the outer diameter of the second sealing portion, and a mounting hole is provided on the second radially extending mounting portion; the outer diameter of the second sealing portion increases gradually along the axial direction toward the side of the second radially extending mounting portion; a second sealing ring is fixed on the outer wall of the second sealing portion; the second sealing ring is used to be clamped between the second sealing portion and the reaming structure.

[0065] A first air inlet group 71 is provided on the front side of the operating table, and a second air inlet group 72 is provided on the back side of the operating table; when the transparent partition 1 is lowered to against the operating table, the cabinet body and the transparent partition 1 form an operating room, and the first air inlet group 71 and the second air inlet group 72 are located in the operating room; an air inlet channel 6 and an exhaust channel 8 are provided in the cabinet body; a first HEPA filter module 81 and an exhaust fan 82 are installed in the exhaust channel 8 in sequence; an air inlet fan 61 and a second HEPA filter module 62 are installed in the air inlet channel 6 from top to bottom; a branch channel is provided in the air inlet channel 6 in the lower area of ​​the second HEPA filter module 62, and the branch channel is connected to the air flow channel through a bellows; a valve is provided on the branch channel; when the transparent partition 1 is in the upper working position, the valve is closed; when the transparent partition 1 is in the lower working position, the valve is open.

[0066] Air flow channels are opened on the left and right sides of the transparent partition 1; air inlet pipes with upward openings are fixed on the left and right sides of the cabinet body, and the air inlet pipes are located below the second HEPA filter module. The air inlet pipes are connected to the bellows through a horizontally arranged extension pipe extending out of the cabinet body, and the bellows are connected to the air flow channels.

[0067] The front notch of the limiting groove is lower than the rear notch of the limiting groove; the rear inner wall of the limiting groove is fixed with staggered baffles to prevent the airflow guided from the transparent partition 1 from flowing into the experimental area.

[0068] Transfer windows 9 are installed on the left and right side walls of the cabinet. The transfer window 9 includes a transfer room. Switch windows are installed on the left and right sides of the transfer room.

[0069] See also Figure 8 as well as Figure 9 Specific embodiment 2, based on specific embodiment 1, has a storage cabinet 10 installed at the bottom of the cabinet body for storing a transparent window 2 and a glove operation window. The storage cabinet 10 is provided with an upper sliding drawer 4 and a lower sliding drawer 5 arranged vertically. The upper sliding drawer 4 is used to place the transparent window 2, while the lower sliding drawer 5 is used to place the glove fixing flange 3. Both the upper sliding drawer 4 and the lower sliding drawer 5 have a U-shaped notch 51. The outer edge of the U-shaped notch 51 has an overlapping groove 52 for sliding components horizontally therein. This facilitates component storage. The transparent window 2 and the glove operation window can be installed alternately according to different usage requirements.

[0070] A UV germicidal lamp is installed at the top and bottom of the storage cabinet to facilitate UV sterilization. A door is installed on the front of the storage cabinet, and a control switch for turning the UV germicidal lamp on and off is installed on the door. The control switch is located on the connection line between the power supply and the UV germicidal lamp.

[0071] Although specific embodiments of the present invention have been described above, those skilled in the art will appreciate that these are merely illustrative and that the scope of the present invention is defined by the appended claims. Those skilled in the art may make various changes or modifications to these embodiments without departing from the principles and essence of the present invention, and such changes and modifications are intended to fall within the scope of the present invention.

Claims

1. A biosafety laboratory cabinet with adjustable airtightness, comprising a biosafety cabinet body, the biosafety cabinet body comprising a cabinet body, an operating table, and a transparent partition at the front of the cabinet body that is arranged to rise and fall and slide, characterized in that: The transparent partition is provided with two operating ports arranged on the left and right, and a mounting flange is fixed on the outer side of the operating port; The mounting flange is detachably connected to a transparent window or a glove operation window; The glove operation window includes a glove and a glove fixing flange for fixing the glove cuff, and the glove fixing flange is detachably connected to the mounting flange; The transparent partition is provided with an upper working position and a lower working position arranged up and down during the lifting process; An air flow channel is provided on the transparent partition, the top of the air flow channel is connected to the air outlet of an air inlet fan, a strip opening is provided on the lower side of the transparent partition and is connected to the air flow channel, the strip opening is used to guide the isolation air curtain, a limiting groove is provided on the operating table for embedding the transparent partition, and the bottom of the limiting groove is connected to an exhaust pipe connected to the strip opening; When the transparent partition is in the upper working position, there is an operating space for accommodating hands between the transparent partition and the operating table; When the transparent partition is in the lower working position, the transparent partition is against the limiting groove, and the strip-shaped opening is facing the exhaust pipe, and there is a gap between the strip-shaped opening and the exhaust pipe.

2. A biosafety laboratory cabinet with adjustable airtightness as claimed in claim 1, characterized in that: A first air inlet group is provided on the front side of the operating table, and a second air inlet group is provided on the rear side of the operating table; When the transparent partition is lowered to abut against the operating table, the cabinet and the transparent partition form an operating room, and the first air inlet hole group and the second air inlet hole group are located in the operating room; An air inlet channel and an air exhaust channel are provided in the cabinet; A first HEPA filter module and an exhaust fan are sequentially installed in the exhaust channel; The air inlet fan and the second HEPA filter module are installed in the air inlet channel from top to bottom; The air inlet channel is located below the second HEPA filter module and has a branch channel, and the branch channel is connected to the air flow channel through a bellows; A valve is provided on the branch channel; When the transparent partition is in the upper working position, the valve is closed; When the transparent partition is in the lower working position, the valve is opened.

3. The biosafety laboratory cabinet with adjustable airtightness according to claim 1, characterized in that: Transfer windows are installed on the left and right side walls of the cabinet, and the transfer window includes a transfer room. Switch windows are installed on the left and right sides of the transfer room.

4. The biosafety laboratory cabinet with adjustable airtightness according to claim 1, characterized in that: A storage cabinet for storing the transparent window and the glove operation window is installed at the bottom of the cabinet; The storage cabinet is provided with an upper sliding drawer plate and a lower sliding drawer plate arranged up and down; The upper sliding drawer is used to place the transparent window; The lower sliding drawer plate is used to place the glove fixing flange; The upper sliding drawer plate and the lower sliding drawer plate are both provided with a U-shaped notch; and the outer edge of the U-shaped notch is provided with a lap groove for sliding a component in transversely.

5. The biosafety laboratory cabinet with adjustable airtightness according to claim 4, characterized in that: An ultraviolet germicidal lamp is installed on the top and bottom of the storage cabinet.

6. A biosafety laboratory cabinet with adjustable airtightness as claimed in claim 5, characterized in that: A cabinet door is installed on the front side of the storage cabinet. A control switch for controlling the opening and closing of the ultraviolet germicidal lamp is installed on the cabinet door. The control switch is located on the connection line between the power supply and the ultraviolet germicidal lamp.

7. A biosafety laboratory cabinet with adjustable airtightness as claimed in claim 2, characterized in that: The air flow channels are provided on the left and right sides of the transparent partition; Air intake pipes with upward openings are fixed on the left and right sides of the cabinet body. The air intake pipes are located below the second HEPA filter module. The air intake pipes are connected to the bellows through an extension pipe that is horizontally arranged and extends out of the cabinet body. The bellows is connected to the air flow channel.

8. The biosafety laboratory cabinet with adjustable airtightness according to claim 1, characterized in that: The inner wall of the mounting flange is an outward-expanding hole structure, a blind hole is opened on the mounting flange, and the inner wall of the blind hole is provided with an internal thread.

9. The biosafety laboratory cabinet with adjustable airtightness according to claim 8, characterized in that: The glove fixing flange comprises a first sealing portion, a first radially extending mounting portion and a glove mounting portion sequentially connected along the axial direction; The first sealing portion, the first radially extending mounting portion, and the glove mounting portion are all provided with through holes that are interconnected; The outer diameter of the first radially extending mounting portion is greater than the outer diameter of the first sealing portion, and a mounting hole is formed on the first radially extending mounting portion; The outer diameter of the first sealing portion increases gradually along the axial direction toward the first radially extending mounting portion; A first sealing ring is fixed on the outer wall of the first sealing portion, and the first sealing ring is used to be sandwiched between the first sealing portion and the hole expansion structure; The cuff of the glove is sleeved on the outside of the glove mounting portion and is fixed by an elastic ring.

10. The biosafety laboratory cabinet with adjustable airtightness according to claim 8, characterized in that: The transparent window comprises a second sealing portion and a second radially extending mounting portion sequentially connected along the axial direction; The outer diameter of the second radially extending mounting portion is greater than the outer diameter of the second sealing portion, and a mounting hole is formed on the second radially extending mounting portion; The outer diameter of the second sealing portion increases axially toward the second radially extending mounting portion; A second sealing ring is fixed on the outer wall of the second sealing portion; the second sealing ring is used to be sandwiched between the second sealing portion and the hole expansion structure.

Citation Information

Patent Citations

  • Three-grade biological safety cabinet

    CN101862688A

  • Comfortable-operation biological safety cabinet

    CN101983772A