Targeted prebiotic plant extraction dietary powder for conditioning hyperglycemia and preparation method thereof
Through the preparation method of targeted prebiotic plant extract dietary powder, the problems of probiotic survival rate and stability of hypoglycemic substances are solved, and efficient blood sugar management effect is achieved, which meets personalized needs and provides reliable guarantee for long-term conditioning.
Patent Information
- Application Number
- CN202510970485.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-15
- Publication Date
- 2025-09-05
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing high-glycemic dietary supplements make it difficult to ensure the survival rate of probiotics in the gastric acid environment during the preparation process. Plant extracts are easily degraded due to high temperature or high humidity treatment, the biological activity of key hypoglycemic substances is attenuated, and the mixing process lacks precise homogeneity control, affecting the stability of efficacy.
The preparation method of targeted prebiotic plant extract dietary powder includes sugar absorption blocking mixed components, cell metabolism activation formula, intestinal source regulation matrix and targeted probiotic complex. Through low-temperature dehydration, microencapsulation technology and triple mixing process, the stability and uniform distribution of active ingredients are ensured. Combined with nitrogen filling encapsulation and water activity control, the shelf life is extended.
The colonization rate of probiotics in the intestine and the biological activity of hypoglycemic substances are maintained, ensuring the accurate dosage of each bag to meet the needs of personalized blood sugar management. The effectiveness of the product in the real digestive environment is verified through full-process quality control, providing reliable guarantee for long-term conditioning.
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Figure CN120585082A_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of health foods, and specifically relates to a targeted prebiotic plant extract dietary powder for regulating hyperglycemia and a preparation method thereof. Background Art
[0002] Plant-derived dietary powder is a nutritional supplement made from natural plants using modern technology to extract their active ingredients. It utilizes a variety of medicinal and edible plants, such as goji berries, chrysanthemums, and red dates, and utilizes advanced processing to extract their essence, preserving the plant's vitamins, minerals, polyphenols, and other beneficial substances to the greatest extent possible. This dietary powder contains no or minimal additives, making it healthy and safe. It is convenient to consume, requiring only warm water. It replenishes nutrients that may be missing from the daily diet, boosts immunity, and improves bodily functions. For those who pursue a healthy lifestyle and prioritize well-being, plant-derived dietary powder is an ideal nutritional supplement, helping them draw vitality from natural plants and maintain a healthy balance.
[0003] However, in the existing technology, traditional high-glycemic dietary supplements generally have the following core defects: their preparation process makes it difficult to ensure the survival rate of probiotics in the gastric acid environment, resulting in the inability of active ingredients to effectively colonize the intestines; plant extracts are easily degraded due to high temperature or high humidity treatment, and the biological activity of key hypoglycemic substances is greatly attenuated; the mixing process lacks precise homogeneous control, resulting in uneven dosage distribution, affecting the stability of efficacy. Summary of the Invention
[0004] The purpose of the present invention is to provide a targeted prebiotic plant extract dietary powder for regulating hyperglycemia and a preparation method thereof in order to solve the above-mentioned problems.
[0005] The technical solution adopted by the present invention is as follows: a targeted prebiotic plant extract dietary powder for regulating hyperglycemia, the dietary powder comprising:
[0006] Sugar Absorption Blocking Mix Ingredients:
[0007] White kidney bean extract: 15-20 parts by weight;
[0008] L-arabinose: 5-10 parts by weight;
[0009] Mulberry leaf DNJ extract: 8-12 parts by weight.
[0010] Cell metabolism activation formula:
[0011] Momordica charantia extract: 10-15 parts by weight;
[0012] Cinnamon extract: 5-8 parts by weight;
[0013] Chromium picolinate: 0.1-0.3 parts by weight.
[0014] Intestinal source regulatory matrix:
[0015] Resistant dextrin: 25-30 parts by weight;
[0016] Fructooligosaccharides: 10-15 parts by weight.
[0017] Targeted Probiotic Complex:
[0018] Lactobacillus plantarum CCFM8610: 8-10 parts by weight;
[0019] Lactobacillus acidophilus NCFM: 5-8 parts by weight;
[0020] Bifidobacterium bifidum TMC3115: 3-5 parts by weight.
[0021] Auxiliary ingredients:
[0022] Natural lemon powder: 2-3 parts by weight.
[0023] In a preferred embodiment, a method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia comprises the following steps:
[0024] S1: Pre-treated plant extracts
[0025] The white kidney bean extract, mulberry leaf DNJ extract, momordica charantia extract and cinnamon extract were respectively passed through an 80-mesh sieve, placed in a constant temperature drying oven, controlled at 40 degrees Celsius, and dehydrated to a water content of no more than 5%.
[0026] S2: Dry Mix Sugar Blocking and Metabolic Formula
[0027] The pretreated white kidney bean extract, mulberry leaf DNJ extract, L-arabinose, momordica charantia extract, cinnamon extract and chromium picolinate were put into a three-dimensional motion mixer and mixed at a speed of 25 revolutions per minute for 30 minutes until completely uniform.
[0028] S3: Prebiotic Matrix Preparation
[0029] Resistant dextrin and oligofructose were added to a wet granulator and sprayed with purified water in an amount of 10% by weight of the total material to prepare prebiotic granules with a particle size of 0.3 to 0.5 mm.
[0030] S4: Microencapsulated Probiotics
[0031] Lactobacillus plantarum CCFM8610, Lactobacillus acidophilus NCFM and Bifidobacterium bifidum TMC3115 were mixed with sodium alginate solution, and 2% by mass calcium chloride solution was dropped into the mixture through a sharp hole method to generate microcapsules with a diameter of 0.2 mm, which were freeze-dried and then used for later use.
[0032] S5: Final product mixing
[0033] The dry mix, prebiotic granules, and microencapsulated probiotics were placed in a V-type blender, natural lemon powder was added, and the mixture was mixed at 20 rpm for 45 minutes until completely homogenized.
[0034] S6: Packaging and nitrogen filling
[0035] The mixed powder is filled into aluminum foil bags at a rate of 3 g per bag, nitrogen is injected into the bag so that the residual oxygen content is no more than 0.5%, and the bag is heat-sealed.
[0036] S7: Activity and stability testing
[0037] Random sampling inspection:
[0038] The activity of probiotics is verified according to the national standard GB 4789.35 method, and the number of viable bacteria is not less than 60 billion CFU per bag;
[0039] Gastric acid tolerance: After being treated with simulated gastric fluid at pH 3 for 2 hours, the survival rate is not less than 92%;
[0040] The water activity is tested according to the national standard GB 5009.3 method, and the result is not higher than 0.15.
[0041] S8: Storage Condition Specifications
[0042] The finished product should be stored in a cool and dry environment with a temperature not exceeding 25 degrees Celsius and a relative humidity not exceeding 30%. Avoid exposure to light and the shelf life is 24 months.
[0043] In a preferred embodiment, in step S1, the white kidney bean extract, mulberry leaf DNJ extract, momordica charantia extract, and cinnamon extract are sequentially finely sieved through an 80-mesh standard sieve. After sieving, the materials are transferred to a constant-temperature drying oven. The drying temperature is strictly set at 40°C, and the dehydration process is continued until the moisture content of the materials drops below 5%. This step ensures the stability of the plant active ingredients and prevents microbial growth or agglomeration caused by excessive moisture in subsequent processes.
[0044] In a preferred embodiment, in step S2, the pretreated plant extract, L-arabinose, and chromium picolinate are added to a three-dimensional motion mixer. The mixer is operated at a fixed speed of 25 revolutions per minute for 30 minutes. During the mixing process, the powder state is monitored in real time to ensure that all materials meet the standards of uniform color, fine texture, and no visible lumps or stratification. Mixing uniformity is confirmed by multi-point sampling.
[0045] In a preferred embodiment, in step S3, the resistant dextrin and oligofructose are placed in a wet granulator in a proportional manner, and purified water is sprayed as a binder, with the water spray rate precisely controlled to 10% of the total weight of the materials. The granulator parameters are adjusted to produce spherical granules with a particle size of 0.3 mm to 0.5 mm. After granulation, the granules are immediately transferred to a fluidized bed dryer at 40 degrees Celsius for 30 minutes to ensure that the granules have moderate hardness and good fluidity.
[0046] In a preferred embodiment, in step S4, powders of Lactobacillus plantarum CCFM8610, Lactobacillus acidophilus NCFM, and Bifidobacterium bifidum TMC3115 are mixed with a 5% sodium alginate solution to form a uniform bacterial suspension. The bacterial suspension is then dripped into a 2% calcium chloride solution at a flow rate of 120 drops per minute through an orifice device to produce microcapsules with a diameter of 0.2 mm. The microcapsules are quick-frozen at -40 degrees Celsius for 2 hours and then transferred to a vacuum freeze dryer with a cold trap temperature of -55 degrees Celsius for 24 hours.
[0047] In a preferred embodiment, in step S5, the dry-mixed sugar blocking formula, prebiotic particles, and microencapsulated probiotics are added to a V-type mixer, and natural lemon powder is added simultaneously. The mixer speed is set to 20 revolutions per minute and operated continuously for 45 minutes. The mixing uniformity is tested using a near-infrared spectrometer, with the relative standard deviation of each component being less than 5%. Samples are taken every 15 minutes during the mixing process to ensure no stratification.
[0048] In a preferred embodiment, in step S6, the mixed powder is dispensed into aluminum foil composite film bags using an automatic filling machine at a precision of 3 grams per bag. Immediately after filling, 99.99% high-purity nitrogen is injected into the bags. After nitrogen displacement, the residual oxygen content in the bag headspace does not exceed 0.5%. The heat-sealing temperature is set at 180°C, the heat-sealing pressure is 0.3 MPa, and the heat-sealing time is 1.5 seconds, achieving a triple seal.
[0049] In a preferred embodiment, in step S7, 30 bags of finished product are randomly sampled from each batch and tested for total viable counts according to national standard GB 4789.35, with a requirement of no less than 60 billion CFU per bag. A gastric acid tolerance test is performed using simulated gastric fluid at pH 3.0 for 2 hours, with a strain survival rate of at least 92%. Water activity is tested according to GB 5009.3, with a result not exceeding 0.15. A batch that fails any of these three tests is deemed unqualified.
[0050] In a preferred embodiment, in step S8, the finished product warehouse is equipped with a constant temperature and humidity system, maintaining a temperature between 20 and 25 degrees Celsius and a relative humidity strictly controlled below 30%. The warehouse is designed to be light-proof, and products are stored 30 centimeters above the ground on moisture-proof pallets. Stability checks are conducted quarterly, including retesting of viable cell counts and verification of water activity. The shelf life is confirmed to be 24 months.
[0051] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are:
[0052] 1. In the present invention, multiple beneficial effects are achieved through scientific process design. First, the method adopts step-by-step precise processing technology to ensure the stability and functionality of the core active ingredients. After low-temperature dehydration, the plant extract retains the biological activity of hypoglycemic substances such as mulberry leaf DNJ and momordica charantia; the probiotics form a gastric acid-resistant barrier through microencapsulation technology to ensure the colonization rate of the strain in the intestine; the triple mixing process makes the sugar-blocking components and the metabolic activation components evenly distributed, synergistically exerting the effect of controlling sugar. Nitrogen filling packaging and water activity control during the preparation process effectively extend the shelf life of the product, avoid oxidative inactivation of active ingredients, and provide reliable protection for long-term conditioning.
[0053] 2. In the present invention, the unity of safety and efficacy is achieved through full-process quality control. The compounding process of prebiotic particles and microencapsulated bacterial strains strengthens the ability of intestinal flora to rebuild, promotes the production of short-chain fatty acids to improve insulin sensitivity; the final product mixing and homogenization technology ensures accurate dosage of each bag to meet the personalized needs of blood sugar management. The stability verification link verifies the effectiveness of the product in a real digestive environment through simulated gastric fluid testing and viable bacteria counts. The entire preparation method not only optimizes the limitations of traditional dietary supplements, but also provides a health solution with both scientific basis and practical value for people with high blood sugar through technological innovation. BRIEF DESCRIPTION OF THE DRAWINGS
[0054] Figure 1 It is a schematic diagram of the process principle of the present invention. DETAILED DESCRIPTION
[0055] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.
[0056] Example:
[0057] Reference Figure 1 , a targeted prebiotic plant extract dietary powder for regulating high blood sugar, characterized in that the dietary powder comprises:
[0058] Sugar Absorption Blocking Mix Ingredients:
[0059] White kidney bean extract (containing α-amylase inhibitor): 15-20 parts by weight;
[0060] L-arabinose: 5-10 parts by weight;
[0061] Mulberry leaf DNJ extract (containing 1% DNJ): 8-12 parts by weight.
[0062] Cell metabolism activation formula:
[0063] Momordica charantia extract (containing 10% momordica charantia saponins): 10-15 parts by weight;
[0064] Cinnamon extract (containing 5% cinnamon polyphenols): 5-8 parts by weight;
[0065] Chromium picolinate: 0.1-0.3 parts by weight.
[0066] Intestinal source regulatory matrix:
[0067] Resistant dextrin: 25-30 parts by weight;
[0068] Fructooligosaccharides (FOS): 10-15 parts by weight.
[0069] Targeted Probiotic Complex:
[0070] Lactobacillus plantarum CCFM8610 (lyophilized powder): 8-10 parts by weight;
[0071] Lactobacillus acidophilus NCFM (lyophilized powder): 5-8 parts by weight;
[0072] Bifidobacterium bifidum TMC3115 (lyophilized powder): 3-5 parts by weight.
[0073] Auxiliary ingredients:
[0074] Natural lemon powder: 2-3 parts by weight.
[0075] A method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia comprises the following steps:
[0076] S1: Pre-treated plant extracts
[0077] The white kidney bean extract, mulberry leaf DNJ extract, momordica charantia extract and cinnamon extract were respectively passed through an 80-mesh sieve, placed in a constant temperature drying oven, controlled at 40 degrees Celsius, and dehydrated to a water content of no more than 5%.
[0078] S2: Dry Mix Sugar Blocking and Metabolic Formula
[0079] The pretreated white kidney bean extract, mulberry leaf DNJ extract, L-arabinose, momordica charantia extract, cinnamon extract and chromium picolinate were put into a three-dimensional motion mixer and mixed at a speed of 25 revolutions per minute for 30 minutes until completely uniform.
[0080] S3: Prebiotic Matrix Preparation
[0081] Resistant dextrin and oligofructose were added to a wet granulator and sprayed with purified water in an amount of 10% by weight of the total material to prepare prebiotic granules with a particle size of 0.3 to 0.5 mm.
[0082] S4: Microencapsulated Probiotics
[0083] Lactobacillus plantarum CCFM8610, Lactobacillus acidophilus NCFM and Bifidobacterium bifidum TMC3115 were mixed with sodium alginate solution, and 2% by mass calcium chloride solution was dropped into the mixture through a sharp hole method to generate microcapsules with a diameter of 0.2 mm, which were freeze-dried and then used for later use.
[0084] S5: Final product mixing
[0085] The dry mix, prebiotic granules, and microencapsulated probiotics were placed in a V-type blender, natural lemon powder was added, and the mixture was mixed at 20 rpm for 45 minutes until completely homogenized.
[0086] S6: Packaging and nitrogen filling
[0087] The mixed powder is filled into aluminum foil bags at a rate of 3 g per bag, nitrogen is injected into the bag so that the residual oxygen content is no more than 0.5%, and the bag is heat-sealed.
[0088] S7: Activity and stability testing
[0089] Random sampling inspection:
[0090] The activity of probiotics is verified according to the national standard GB 4789.35 method, and the number of viable bacteria is not less than 60 billion CFU per bag;
[0091] Gastric acid tolerance: After being treated with simulated gastric fluid at pH 3 for 2 hours, the survival rate is not less than 92%;
[0092] The water activity is tested according to the national standard GB 5009.3 method, and the result is not higher than 0.15.
[0093] S8: Storage Condition Specifications
[0094] The finished product should be stored in a cool and dry environment with a temperature not exceeding 25 degrees Celsius and a relative humidity not exceeding 30%. Avoid exposure to light and the shelf life is 24 months.
[0095] In step S1, the white kidney bean extract, mulberry leaf DNJ extract, momordica charantia extract, and cinnamon extract are sequentially finely sieved through an 80-mesh standard sieve. After sieving, the materials are transferred to a constant-temperature drying oven. The drying temperature is strictly set at 40°C, and dehydration is continued until the moisture content drops below 5%. This step ensures the stability of the plant active ingredients and prevents microbial growth or agglomeration caused by excessive moisture in subsequent processes.
[0096] In step S2, the pretreated plant extract, L-arabinose, and chromium picolinate are added to a three-dimensional motion mixer. The mixer is operated at a fixed speed of 25 revolutions per minute for 30 minutes. During the mixing process, the powder state is monitored in real time to ensure that all materials meet the standards of uniform color, fine texture, and no visible lumps or stratification. Mixing uniformity is confirmed by multi-point sampling.
[0097] In step S3, the resistant dextrin and oligofructose are placed in a wet granulator in a proportional amount. Purified water is sprayed in as a binder, with the spray rate precisely controlled to 10% of the total weight of the materials. The granulator parameters are adjusted to produce spherical granules with a particle size of 0.3 mm to 0.5 mm. After granulation, the granules are immediately transferred to a fluidized bed dryer at 40 degrees Celsius for 30 minutes to ensure that the granules have moderate hardness and good fluidity.
[0098] In step S4, powders of Lactobacillus plantarum CCFM8610, Lactobacillus acidophilus NCFM, and Bifidobacterium bifidum TMC3115 are mixed with a 5% sodium alginate solution to form a uniform bacterial suspension. This suspension is then dripped into a 2% calcium chloride solution at a rate of 120 drops per minute through an orifice device to produce microcapsules with a diameter of 0.2 mm. The microcapsules are then quick-frozen at -40°C for 2 hours and then transferred to a vacuum freeze dryer with a cold trap temperature of -55°C for 24 hours.
[0099] In step S5, the dry-mixed sugar blocking formula, prebiotic granules, and microencapsulated probiotics are added to a V-type mixer, and natural lemon powder is added simultaneously. The mixer is set to 20 rpm and operated continuously for 45 minutes. The mixing uniformity is tested using a near-infrared spectrometer, with the relative standard deviation of each component being less than 5%. Samples are taken every 15 minutes during the mixing process to ensure no stratification.
[0100] In step S6, the mixed powder is dispensed into aluminum foil composite film bags using an automatic filling machine at a precision of 3 grams per bag. Immediately after filling, 99.99% high-purity nitrogen is injected into the bags. After nitrogen displacement, the residual oxygen content in the bag's headspace does not exceed 0.5%. The heat-sealing temperature is set at 180°C, the heat-sealing pressure is 0.3 MPa, and the heat-sealing time is 1.5 seconds, completing a triple seal.
[0101] In step S7, 30 bags of finished product are randomly sampled from each batch and tested for total viable counts according to national standard GB 4789.35, with a minimum of 60 billion CFU per bag. A gastric acid tolerance test is performed using simulated gastric fluid at pH 3.0 for two hours, with a strain survival rate of at least 92%. Water activity is tested according to GB 5009.3, with a result not exceeding 0.15. Any failure in any of these three tests results in a batch being deemed unqualified.
[0102] In step S8, the finished product warehouse is equipped with a constant temperature and humidity system, maintaining a temperature between 20 and 25 degrees Celsius and a relative humidity strictly controlled below 30%. The warehouse is designed to shield from light, and products are stored 30 centimeters above the ground on moisture-proof pallets. Stability checks are conducted quarterly, including retesting of viable cell counts and verification of water activity. The shelf life is confirmed to be 24 months.
[0103] From the above we can know:
[0104] In the present invention, multiple beneficial effects are achieved through scientific process design. First, the method adopts step-by-step precision processing technology to ensure the stability and functionality of the core active ingredients. After low-temperature dehydration, the plant extract retains the biological activity of hypoglycemic substances such as mulberry leaf DNJ and momordicin; the probiotics form a gastric acid-resistant barrier through microencapsulation technology to ensure the colonization rate of the strain in the intestine; the triple mixing process makes the sugar blocking ingredients and metabolic activation components evenly distributed, synergistically exerting the effect of controlling sugar. Nitrogen encapsulation and water activity control during the preparation process effectively extend the shelf life of the product, avoid oxidative inactivation of active ingredients, and provide reliable protection for long-term conditioning.
[0105] In this invention, the unity of safety and efficacy is achieved through full-process quality control. The compounding process of prebiotic particles and microencapsulated bacterial strains strengthens the intestinal flora reconstruction capacity and promotes the production of short-chain fatty acids to improve insulin sensitivity; the final product mixing and homogenization technology ensures the precise dosage of each bag to meet the personalized needs of blood sugar management. The stability verification link confirms the effectiveness of the product in a real digestive environment through simulated gastric fluid testing and viable bacteria counting. The entire preparation method not only optimizes the limitations of traditional dietary supplements, but also provides a health solution with both scientific basis and practical value for people with high blood sugar through technological innovation.
[0106] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprises" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device that includes a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further limitations, an element defined by the sentence "comprises a ..." does not exclude the presence of other identical elements in the process, method, article or device that includes the element.
[0107] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the present invention.
Claims
1. A targeted prebiotic plant extract dietary powder for regulating hyperglycemia, characterized by: The dietary powder comprises: Sugar Absorption Blocking Mix Ingredients: White kidney bean extract: 15-20 parts by weight; L-arabinose: 5-10 parts by weight; Mulberry leaf DNJ extract: 8-12 parts by weight; Cell metabolism activation formula: Momordica charantia extract: 10-15 parts by weight; Cinnamon extract: 5-8 parts by weight; Chromium picolinate: 0.1-0.3 parts by weight; Intestinal source regulatory matrix: Resistant dextrin: 25-30 parts by weight; Fructooligosaccharides: 10-15 parts by weight; Targeted Probiotic Complex: Lactobacillus plantarum CCFM8610: 8-10 parts by weight; Lactobacillus acidophilus NCFM: 5-8 parts by weight; Bifidobacterium bifidum TMC3115: 3-5 parts by weight; Auxiliary ingredients: Natural lemon powder: 2-3 parts by weight.
2. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: The method comprises the following steps: S1: Pass the white kidney bean extract, mulberry leaf DNJ extract, momordica charantia extract, and cinnamon extract through an 80-mesh sieve, place them in a constant temperature drying oven at 40 degrees Celsius, and dehydrate them to a moisture content of no more than 5%; S2: The pretreated white kidney bean extract, mulberry leaf DNJ extract, L-arabinose, momordica charantia extract, cinnamon extract, and chromium picolinate were placed in a three-dimensional motion mixer and mixed at 25 revolutions per minute for 30 minutes until completely homogenized; S3: Add resistant dextrin and oligofructose into a wet granulator and spray with purified water in an amount of 10% by weight of the total material to produce prebiotic granules with a particle size of 0.3 to 0.5 mm; S4: Lactobacillus plantarum CCFM8610, Lactobacillus acidophilus NCFM, and Bifidobacterium bifidum TMC3115 were mixed with a sodium alginate solution, and a 2% calcium chloride solution was added dropwise using a sharp hole method to generate microcapsules with a diameter of 0.2 mm, which were freeze-dried and then used for later use; S5: Place the dry mix, prebiotic granules, and microencapsulated probiotics into a V-type mixer, add natural lemon powder, and mix at 20 rpm for 45 minutes until completely homogenized; S6: Fill the mixed powder into aluminum foil bags at a rate of 3 g per bag, fill with nitrogen until the residual oxygen content is no more than 0.5%, and heat-seal the bags; S7: Conduct activity and stability tests, including: Random sampling inspection: The activity of probiotics is verified according to the national standard GB 4789.35 method, and the number of viable bacteria is not less than 60 billion CFU per bag; Gastric acid tolerance: After being treated with simulated gastric fluid at pH 3 for 2 hours, the survival rate is not less than 92%; The water activity is tested according to the national standard GB 5009.3 method, and the result is not higher than 0.15; S8: The finished product should be stored in a cool and dry environment with a temperature not exceeding 25 degrees Celsius and a relative humidity not exceeding 30%. Avoid exposure to light. The shelf life is 24 months.
3. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: In step S1, the white kidney bean extract, mulberry leaf DNJ extract, momordica charantia extract, and cinnamon extract are sequentially finely sieved through an 80-mesh standard sieve. After sieving, the materials are transferred to a constant temperature drying oven; the drying temperature is strictly set to 40 degrees Celsius, and the dehydration process is continued until the moisture content of the materials drops below 5%.
4. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: In step S2, the pretreated plant extract, L-arabinose, and chromium picolinate are added to a three-dimensional motion mixer; the mixer speed is fixed at 25 revolutions per minute and continuously operates for 30 minutes; the powder state is monitored in real time during the mixing process to ensure that all materials meet the standards of uniform color, fine texture, and no visible agglomeration or stratification; and the mixing uniformity is confirmed by multi-point sampling and testing.
5. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: In step S3, resistant dextrin and oligofructose are added to a wet granulator in proportion, and purified water is sprayed as a binder, with the water spraying amount precisely controlled to be 10% of the total weight of the materials; the granulator parameters are adjusted to generate spherical particles with a particle size of 0.3 mm to 0.5 mm; and after granulation is completed, the mixture is immediately transferred to a fluidized bed dryer at 40 degrees Celsius for 30 minutes to ensure that the particles have moderate hardness and good fluidity.
6. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: In step S4, bacterial powders of Lactobacillus plantarum CCFM8610, Lactobacillus acidophilus NCFM and Bifidobacterium bifidum TMC3115 are mixed with a 5% sodium alginate solution to form a uniform bacterial suspension; the bacterial suspension is dripped into a 2% calcium chloride solution at a flow rate of 120 drops per minute through a sharp hole device to generate microcapsules with a diameter of 0.2 mm; the microcapsules are quick-frozen at -40 degrees Celsius for 2 hours and then transferred to a vacuum freeze dryer with a cold trap temperature of -55 degrees Celsius for 24 hours.
7. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: In step S5, the dry-mixed sugar blocking formula, prebiotic particles, and microencapsulated probiotics are added to a V-type mixer, and natural lemon powder is added simultaneously; the mixer speed is set to 20 revolutions per minute and the mixer is operated continuously for 45 minutes; the mixing uniformity is tested by a near-infrared spectrometer, and the relative standard deviation of each component is required to be less than 5%; and samples are taken every 15 minutes during the mixing process to ensure that there is no stratification.
8. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: In step S6, the mixed powder is packaged into aluminum foil composite film bags with a precision of 3 grams per bag by an automatic filling machine; 99.99% high-purity nitrogen is immediately injected into the bag after filling, and the residual oxygen content in the top space of the packaging bag after nitrogen replacement does not exceed 0.5%; the heat sealing temperature is set to 180 degrees Celsius, the heat sealing pressure is 0.3 MPa, and the heat sealing time is 1.5 seconds to complete the triple seal.
9. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: In step S7, 30 bags of finished products are randomly selected from each batch and the total viable count is determined according to the national standard GB 4789.35, which is required to be no less than 60 billion CFU per bag; the gastric acid tolerance test is performed by treating with simulated gastric fluid at a pH of 3.0 for 2 hours, and the strain survival rate must reach more than 92%; the water activity test is performed according to the GB 5009.3 standard, and the result is not more than 0.15; if any of the three tests fails, the batch is judged to be unqualified.
10. The method for preparing a targeted prebiotic plant extract dietary powder for regulating hyperglycemia according to claim 1, characterized in that: In step S8, the finished product warehouse is equipped with a constant temperature and humidity system, the temperature is maintained in the range of 20 to 25 degrees Celsius, and the relative humidity is strictly controlled below 30%; the warehouse adopts a light-proof design, and the products are stored 30 cm above the ground on moisture-proof pallets; stability spot checks are carried out every quarter, including retesting of viable bacteria count and verification of water activity, and the shelf life is confirmed to be 24 months.