One-step taking and placing double-tube sampling system and nuclear magnetic resonance equipment

Abstract

The invention relates to the technical field of nuclear magnetic resonance spectrometers, in particular to a one-step taking and placing double-tube sample injection system and nuclear magnetic resonance equipment, and the one-step taking and placing double-tube sample injection system comprises a double-tube sample transfer piece and a driving assembly. The double-tube sample transfer piece is provided with at least two containing spaces, and each containing space can contain one sample tube. The driving assembly can drive the double-tube sample transfer piece to move back and forth between the sampling position and the sample opening, so that the sample tube at the sampling position can be placed in the empty accommodating space, the sample tube in the other accommodating space can be placed in the sampling position, and the sample tube at the sample opening can be placed in the empty accommodating space; and the sample tube in the other accommodating space can be placed in the sample opening. The nuclear magnetic resonance equipment comprises the double-tube sampling system capable of taking and placing in one step. According to the one-step taking and placing double-pipe sample injection system and the nuclear magnetic resonance equipment, the sample changing efficiency can be improved.

Description

Technical Field

[0001] The present invention relates to the technical field of nuclear magnetic resonance spectrometers, and in particular to a one-step take-and-place double-tube sampling system and a nuclear magnetic resonance device. Background Art

[0002] The sampling system of a nuclear magnetic resonance (NMR) device needs to retrieve sample tubes from a sample carousel and transfer them to the sample port. Patent EP2199816B1, for example, discloses an automatic transport device for NMR measurement samples. This device has a single transport container, TB2. When a sample change is required, TB2 must first be moved to the NMR device's sample port to retrieve the sample tube. After TB2 returns the sample tube to the sample carousel, it can retrieve a new sample tube from the carousel and then transfer the new sample tube to the sample port. This means the sample change process for this automatic transport device for NMR measurement samples is complex and time-consuming. Summary of the Invention

[0003] An object of the present invention is to provide a one-step take-and-place double-tube sampling system, which can improve sample replacement efficiency.

[0004] To achieve this object, the present invention adopts the following technical solutions:

[0005] A one-step access dual-tube injection system is provided, comprising:

[0006] A double-tube sample transfer component, wherein the double-tube sample transfer component has at least two accommodating spaces, each of which can accommodate a sample tube;

[0007] A driving assembly capable of driving the double-tube sample transfer component to and from the sampling position and the sample port, so that the sample tube at the sampling position can be placed in the empty accommodating space, and the sample tube in the other accommodating space can be placed in the sampling position, and the sample tube at the sample port can be placed in the empty accommodating space, and the sample tube in the other accommodating space can be placed in the sample port.

[0008] Optionally, the driving assembly includes a transmission driving member, which is used to drive the double-tube sample transfer member to move, and the moving trajectories of the centers of at least two of the accommodating spaces are located on the same straight line, and the first position above the sample port and the sampling position are both located on the moving trajectory of the center of the accommodating space.

[0009] Optionally, the accommodating space includes a first accommodating space and a second accommodating space. When the double-tube sample transfer component moves toward the first position, the moving direction is the first direction. The first accommodating space and the second accommodating space are arranged in sequence along the first direction. The transmission drive component can drive the double-tube sample transfer component to move so that the first accommodating space is located in the first position.

[0010] Optionally, the driving assembly further includes a first hook driving member and a first hook member, wherein the first hook driving member can drive the first hook member to block the transmission driving member from driving the movement of the double-tube sample transmitting member, so that the second accommodating space is located in the first position.

[0011] Optionally, when the transmission driving member reaches one end of the driving stroke, the first accommodating space is located at the first position;

[0012] And / or, when the first gear hook driving member reaches one end of the driving stroke, the second accommodating space is located at the first position;

[0013] and / or, the other end of the driving stroke of the first gear hook driving member is located at the first position corresponding to the first accommodating space;

[0014] And / or, the distance between the first accommodating space and the second accommodating space is equal to the driving stroke of the first gear hook driving member.

[0015] Optionally, a clamping assembly is further included, wherein the clamping assembly includes a clamping drive and two clamping jaws, and the clamping drive is used to drive the two clamping jaws to move closer to each other to clamp the sample tube, or move away from each other to release the sample tube.

[0016] Optionally, the two clamping jaws have two clamping positions sequentially arranged along the first direction, and each of the clamping positions can accommodate one sample tube.

[0017] Optionally, the clamping assembly further includes a moving drive member, and the moving drive member is used to drive the clamping drive member and the two clamping jaws to move along the first direction.

[0018] Optionally, the distance between the two clamping positions is d, the length of the driving stroke of the movable driving member is s, and the distance between the first accommodating space and the second accommodating space is sd.

[0019] Optionally, the distance d between the two clamping positions and the length s of the driving stroke of the movable driving member satisfy: s=2d.

[0020] Optionally, the driving assembly further includes a second hook driving member and a second hook member, and the second hook driving member can drive the second hook member to block the transmission driving member from driving the movement of the double-tube sample transmitting member, so that any of the clamping positions can correspond to any of the accommodating spaces.

[0021] Optionally, the second gear hook driving member can drive the second gear hook member to move along the first direction, and a driving stroke of the second gear hook driving member is equal to the distance d between the two clamping positions.

[0022] Optionally, each of the accommodating spaces is configured to be through in a vertical direction, and the double-tube sample transfer component includes a limiting component, which can limit the sample tubes from entering and exiting from the upper opening of the accommodating space.

[0023] Optionally, the limiting member has a limiting state and a non-limiting state. In the limiting state, the limiting member limits the sample tube from entering and outputting from the lower opening of the accommodating space. In the non-limiting state, the limiting member cannot limit the sample tube from entering and outputting from the lower opening.

[0024] Optionally, the double-tube sample transmission component also includes a shell and an elastic component, the rotating shaft of the limiting component is connected to the shell, and the limiting component can rotate around the rotating shaft to adjust to the limiting state or the non-limiting state. The elastic component is connected to the shell and the limiting component, and the elastic component is used to make the limiting component have a tendency to be in the limiting state.

[0025] Optionally, a ejector pin is further included, and the ejector pin is arranged at the sample port, and the ejector pin can press the limiting member to adjust the limiting member to the non-limiting state.

[0026] Optionally, a rotating sample disk is further included, which has multiple circles of sample holes, each circle of sample holes includes multiple sample holes arranged at circumferential intervals, the centers of the virtual circles of the multiple circles of sample holes coincide with the rotation center of the rotating sample disk, and the sample tubes are placed in the sample holes.

[0027] Optionally, the moving drive member is used to drive the clamping drive member and the two clamping claws to move along the radial direction of the rotating sample disk, and the two clamping positions are sequentially arranged along the radial direction of the rotating sample disk.

[0028] Optionally, the rotating sample disk has four circles of sample holes, and along the radial direction of the rotating sample disk, the four circles of sample holes are the first circle, the second circle, the third circle and the fourth circle. When the mobile driving member executes to one end of the driving stroke, the two clamping positions respectively correspond to the position on the first circle and the position on the second circle. When the mobile driving member executes to the other end of the driving stroke, the two clamping positions respectively correspond to the position on the third circle and the position on the fourth circle.

[0029] Another object of the present invention is to provide a nuclear magnetic resonance device that can improve sample replacement efficiency.

[0030] To achieve this object, the present invention adopts the following technical solutions:

[0031] Provided is a nuclear magnetic resonance device comprising the above-mentioned one-step pick-and-place double-tube sample injection system.

[0032] Beneficial effects of the present invention:

[0033] The present invention provides a one-step take-and-place double-tube sample feeding system, comprising a double-tube sample transfer unit and a drive assembly. The double-tube sample transfer unit has at least two accommodating spaces, each of which can accommodate a sample tube. The drive assembly can drive the double-tube sample transfer unit to and from the sampling position and the sample port, so that the sample tube at the sampling position can be placed in an empty accommodating space, the sample tube in the other accommodating space can be placed in the sampling position, and the sample tube at the sample port can be placed in an empty accommodating space, and the sample tube in the other accommodating space can be placed in the sample port. By providing a double-tube sample transfer unit with at least two accommodating spaces, when the double-tube sample transfer unit is at the sample port, the empty accommodating space can be used to obtain the sample tube output at the sample port, and then the new sample tube in the other accommodating space can be input into the sample port, so that the sample changing step at the sample port can be completed at one time, greatly improving the sample changing efficiency.

[0034] The present invention provides a nuclear magnetic resonance device comprising the above-mentioned one-step pick-and-place double-tube sample introduction system. The nuclear magnetic resonance device can improve sample exchange efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 It is a partial structural diagram of a nuclear magnetic resonance device provided by an embodiment of the present invention;

[0036] Figure 2 This is a partial structural diagram of a one-step access dual-tube sample injection system provided by an embodiment of the present invention;

[0037] Figure 3 is a structural schematic diagram of a clamping assembly provided by an embodiment of the present invention;

[0038] Figure 4Schematic diagram of the cooperation between the clamping assembly (extended state) and the double-tube sample transfer unit provided in an embodiment of the present invention;

[0039] Figure 5 Schematic diagram of the cooperation between the clamping assembly (retracted state) and the double-tube sample transfer unit provided by an embodiment of the present invention;

[0040] Figure 6 Schematic diagram of the cooperation between the clamping assembly (retracted state) and the double-tube sample transfer unit (leftward movement) provided in an embodiment of the present invention;

[0041] Figure 7 1 is a schematic diagram of the cooperation between the double-tube sample transfer component and the ejector pin provided by an embodiment of the present invention from a first perspective;

[0042] Figure 8 1 is a schematic diagram showing the cooperation between the double-tube sample transfer element and the ejector pin provided by an embodiment of the present invention from a second perspective;

[0043] Figure 9 It is a structural schematic diagram of the rotating sample disk provided by an embodiment of the present invention.

[0044] In the picture:

[0045] 1. Double-tube sample transfer unit; 101. First accommodating space; 102. Second accommodating space; 103. Housing; 104. Positioning member; 1041. Pin; 1042. Rotating rod; 1043. Rotating shaft;

[0046] 2. Transmission drive member; 3. First gear hook drive member; 4. First gear hook member; 5. Clamping drive member;

[0047] 6. Clamping jaws; 61. First clamping position; 62. Second clamping position;

[0048] 7. Mobile driving member; 8. Second gear hook driving member; 9. Second gear hook member; 10. Ejector seat; 11. Ejector;

[0049] 12. Rotating sample plate; 121. First rotation; 1211. Sample hole; 122. Second rotation; 123. Third rotation; 124. Fourth rotation;

[0050] 13. Vertical drive member;

[0051] 100. Sample tube. DETAILED DESCRIPTION

[0052] Before any embodiments of the present application are explained in detail, it is to be understood that the application is not limited in its application to the details of construction and the arrangement of components set forth in the following description or illustrated in the foregoing drawings.

[0053] In this application, the terms "comprises," "includes," "has," or any other variations thereof are intended to encompass non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not preclude the presence of additional identical elements in the process, method, article, or apparatus that includes the element.

[0054] In this application, the term "and / or" describes a relationship between related objects, indicating that three possible relationships exist. For example, "A and / or B" can represent: A exists alone, A and B exist simultaneously, or B exists alone. Additionally, the character " / " in this application generally indicates that the related objects are in an "and / or" relationship.

[0055] In this application, the terms "connect," "combine," "couple," and "install" may refer to direct connection, combination, coupling, or installation, or indirect connection, combination, coupling, or installation. For example, a direct connection refers to two parts or components being connected together without an intermediary, and an indirect connection refers to two parts or components being connected to at least one intermediary, with the two parts or components being connected via the intermediary. Furthermore, "connect" and "couple" are not limited to physical or mechanical connections or couplings and may include electrical connections or couplings.

[0056] In this application, it will be understood by those skilled in the art that relative terms (e.g., "about," "approximately," "substantially," etc.) used in conjunction with quantities or conditions include the values ​​and have the meaning indicated by the context. For example, the relative terms include at least the degree of error associated with the measurement of a specific value, the tolerance caused by manufacturing, assembly, use, etc. associated with a specific value. Such terms should also be considered to disclose a range defined by the absolute values ​​of the two endpoints. Relative terms may refer to plus or minus a certain percentage (e.g., 1%, 5%, 10% or more) of the indicated value. Numerical values ​​that do not use relative terms should also be disclosed as specific values ​​with tolerances. In addition, "substantially" may refer to plus or minus a certain degree (e.g., 1 degree, 5 degrees, 10 degrees or more) on the basis of the indicated angle when expressing a relative angular position relationship (e.g., substantially parallel, substantially perpendicular).

[0057] In this application, it will be understood by those skilled in the art that the function performed by an assembly can be performed by one assembly, multiple assemblies, one part, or multiple parts. Similarly, the function performed by a part can also be performed by one part, one assembly, or a combination of multiple parts.

[0058] In the present application, the terms "upper", "lower", "left", "right", "front", "back" and other directional words are described based on the orientation and positional relationship shown in the accompanying drawings, and should not be understood as limiting the embodiments of the present application. In addition, in the context, it is also necessary to understand that when it is mentioned that an element is connected to another element "upper" or "lower", it can not only be directly connected to the other element "upper" or "lower", but also be indirectly connected to the other element "upper" or "lower" through an intermediate element. It should also be understood that directional words such as upper side, lower side, left side, right side, front side, back side, etc. not only represent the positive orientation, but can also be understood as the lateral orientation. For example, below can include directly below, lower left, lower right, lower front and lower back, etc.

[0059] When the transport device of the sampling system of the nuclear magnetic resonance equipment has only one accommodating space, when the sample needs to be changed, the transport device must first be moved to the sample port of the nuclear magnetic resonance equipment to obtain the sample tube output from the sample port. After the transport device returns the sample tube to the sample turntable, the transport device can obtain a new sample tube in the sample turntable and then send the new sample tube to the sample port. It can be seen that the sample changing process of the transport device is cumbersome and time-consuming.

[0060] In order to solve the above problems, this embodiment provides a one-step-pick-and-place dual-tube sample injection system, which can improve sample exchange efficiency.

[0061] like Figures 1-9 As shown, the one-step access dual-tube sample injection system of this embodiment includes a dual-tube sample transfer unit 1 and a drive assembly. The dual-tube sample transfer unit 1 has at least two accommodating spaces, each of which can accommodate a sample tube 100. The drive assembly can drive the dual-tube sample transfer unit 1 back and forth between the sampling position and the sample port, so that the sample tube 100 at the sampling position can be placed in an empty accommodating space, while the sample tube 100 in the other accommodating space can be placed in the sampling position, and the sample tube 100 at the sample port can be placed in an empty accommodating space, while the sample tube 100 in the other accommodating space can be placed in the sample port.

[0062] By providing a double-tube sample transfer component 1 with at least two accommodating spaces, when the double-tube sample transfer component 1 is at the sample port, the empty accommodating space can be used to obtain the sample tube 100 output from the sample port, and then a new sample tube 100 in the other accommodating space can be input into the sample port, thereby completing the sample replacement steps at the sample port at one time, greatly improving the sample replacement efficiency.

[0063] Optionally, the drive assembly includes a transmission drive 2, which is used to drive the double-tube sample transfer component 1 to move, and the moving trajectories of the centers of at least two accommodating spaces are located on the same straight line, and the first position above the sample port and the sampling position are both located on the moving trajectory of the center of the accommodating space, which can ensure that the sample tube 100 in the accommodating space can fall into the sample port, and the sample tube 100 at the sample port can pop up and enter the accommodating space. Of course, there needs to be a corresponding component in the accommodating space to limit the sample tube 100 entering, and this part of the structure will be introduced later. In this embodiment, the transmission drive 2 extends in the horizontal direction. Optionally, the transmission drive 2 is a horizontal cylinder.

[0064] Optionally, the accommodating space includes a first accommodating space 101 and a second accommodating space 102. When the double-tube sample transmitter 1 moves toward the first position, the movement direction is the first direction. The first accommodating space 101 and the second accommodating space 102 are arranged sequentially along the first direction. The transmission drive 2 can drive the double-tube sample transmitter 1 to move so that the first accommodating space 101 is located in the first position. That is, during the process of the double-tube sample transmitter 1 moving toward the first position, the second accommodating space 102 is closer to the first position than the first accommodating space 101. That is, during the process of the double-tube sample transmitter 1 moving toward the first position, the second accommodating space 102 is located in the first position first, and the first accommodating space 101 is located in the first position later.

[0065] Since multiple storage spaces allow for seamless sample changes and improve sample change efficiency, why do existing technologies all use a single storage space setup? The reason is that the sampling system of a nuclear magnetic resonance device has extremely high precision requirements. The sample detection area is strictly limited to a uniform field with a diameter of millimeters at the center of the magnet, which means that the sampling system needs to achieve millimeter-level positioning accuracy. However, since the horizontal cylinder that drives the movement of the dual-tube sample transfer unit 1 has only two stop points for precise positioning, namely the two ends of the driving stroke, when the dual-tube sample transfer unit 1 moves to the sample port, it is impossible to achieve two precise positioning points for the two storage spaces to be located in the first position.

[0066] There are usually two ways to add a positioning point at one end of the horizontal cylinder drive stroke:

[0067] 1. A detection switch (such as a photoelectric switch, proximity switch, etc.) is set at one end of the horizontal cylinder's driving stroke. The detection switch is used to control the stroke of the horizontal cylinder. This control method is simple, but it cannot guarantee the accuracy of positioning. The horizontal cylinder will only stop near the detection switch, which cannot meet the high-precision requirements of the nuclear magnetic resonance equipment for the injection system.

[0068] 2. The horizontal cylinder is a rodless cylinder, so it must have a driving slide. A secondary cylinder is set on the driving slide of the horizontal cylinder to add a positioning point at one end of the driving stroke of the horizontal cylinder through the secondary cylinder. The main problem of this solution is that the secondary cylinder has a drag line, that is, an air pipe, which will affect the positioning accuracy of the horizontal cylinder.

[0069] Therefore, the above two methods cannot meet the high precision requirements of the nuclear magnetic resonance equipment for the injection system. Figure 2 As shown, in this embodiment, the drive assembly further includes a first stopper driver 3 and a first stopper 4. The first stopper driver 3 is capable of driving the first stopper 4 to block the movement of the transport driver 2 in driving the dual-tube sample transfer member 1, thereby positioning the second accommodating space 102 in the first position. Specifically, to improve the movement accuracy of the dual-tube sample transfer member 1, thereby ensuring the precise positioning of the accommodating space in the first position and the precise positioning of the sample tube 100 entering the sample port, when the transport driver 2 reaches the end of its driving stroke, the first accommodating space 101 of the dual-tube sample transfer member 1 is precisely positioned in the first position. At this point, the first stopper driver 3 drives the first stopper 4 to a position where it does not block the transport driver 2 from driving the dual-tube sample transfer member 1. When the first stopper driver 3 drives the first stopper 4 to a position where it blocks the transport driver 2 from driving the dual-tube sample transfer member 1, the dual-tube sample transfer member 1 moves in a direction opposite to the first direction until the second accommodating space 102 is precisely positioned in the first position.

[0070] To ensure the displacement accuracy of the first hook driver 3 driving the first hook member 4, and because the first hook driver 3 is a hook cylinder, that is, the first hook driver 3 also has only two stop points for precise positioning, namely, the two ends of the driving stroke. Through debugging, the hook cylinder and the transmission driver 2 are given appropriate respective driving forces and driving force differences to ensure positioning accuracy. Therefore, when the first hook driver 3 reaches one end of the driving stroke, the first hook member 4 is located at a position that does not block the transmission driver 2 from driving the double-tube sample transmitter 1. When the first hook driver 3 reaches the other end of the driving stroke, the first hook member 4 is located at a position that blocks the transmission driver 2 from driving the double-tube sample transmitter 1. Accordingly, the first hook member 4 pushes the double-tube sample transmitter 1 to move to the second accommodating space 102 and is located at the first position.

[0071] Optionally, when the driving stroke of the first gear hook driving member 3 ends, it can also correspond to the first accommodating space 101 being at the first position. In this case, the distance between the first accommodating space 101 and the second accommodating space 102 is equal to the driving stroke of the first gear hook driving member 3.

[0072] Alternatively, as Figure 1As shown, the one-step dual-tube sampling system further includes a gripping assembly, which includes a gripping drive 5 and two gripping jaws 6. The gripping drive 5 is used to drive the two gripping jaws 6 toward each other to grip the sample tube 100, or away from each other to release the sample tube 100. The gripping assembly is used to transport the sample tube 100 back and forth between the rotating sample tray 12 and the accommodating space of the dual-tube sample transfer unit 1.

[0073] Optionally, the drive assembly further includes a vertical drive member 13, which is used to drive the clamping assembly to move in the vertical direction. The clamping assembly can then move downward to approach the rotating sample disk 12, and the clamping assembly can then place the sample tube 100 on the rotating sample disk 12, or remove the sample tube 100 from the rotating sample disk 12. The clamping assembly can also move upward to be higher than the double-tube sample transfer member 1. When the double-tube sample transfer member 1 returns to the sampling position close to the clamping assembly, the clamping assembly can then move downward again to approach the double-tube sample transfer member 1, and the clamping assembly can then remove the sample tube 100 from the double-tube sample transfer member 1, or place a new sample tube 100 taken from the rotating sample disk 12 into the accommodating space of the double-tube sample transfer member 1.

[0074] Optionally, the rotating sample disk 12 has multiple circles of sample holes 1211. When the outer diameter of the rotating sample disk 12 is constant, a greater number of sample holes 1211 can accommodate more sample tubes 100, thereby improving work efficiency. Furthermore, when the total number of sample holes 1211 is constant, an appropriate increase in the number of circles can reduce the outer diameter of the rotating sample disk 12. When the rotation angle of the rotating sample disk 12 is constant, a smaller outer diameter results in a smaller arc of rotation, which is more conducive to ensuring rotation accuracy.

[0075] Optionally, each circle of sample holes 1211 includes multiple sample holes 1211 arranged at circumferential intervals, and the centers of the virtual circles of the multiple circles of sample holes 1211 coincide with the rotation center of the rotating sample disk 12, that is, the distance between the sample holes 1211 in the same circle and the rotation center is the same, and the sample tube 100 is placed in the sample hole 1211.

[0076] Optionally, in this embodiment, the rotating sample disk 12 has four circles of sample holes 1211 , which are arranged from inside to outside along the radial direction of the rotating sample disk 12 , namely, a first circle 121 , a second circle 122 , a third circle 123 and a fourth circle 124 .

[0077] In order to accurately pick and place the sample tubes 100 on each circle, optionally, as Figure 3-Figure 6As shown, the two clamping jaws 6 have two clamping positions arranged in sequence along the first direction, each clamping position can accommodate a sample tube 100, and the two clamping positions are the first clamping position 61 and the second clamping position 62 in the figure. The arrangement direction of the two clamping positions is consistent with the arrangement direction of the two accommodating spaces, which can ensure that any clamping position corresponds precisely to any accommodating space. It should be noted that since the two clamping jaws 6 can move in the vertical direction, the direction consistency mentioned here refers to the situation where the clamping position and the accommodating space are exactly at the same height. Of course, in the actual sample changing process, the clamping position is located above the accommodating space.

[0078] Optionally, the direction of the line connecting the first clamping position 61 and the second clamping position 62 coincides with the radial direction of the rotating sample disk 12. It should be noted that, since the two clamping jaws 6 can move in the vertical direction, the direction coincidence mentioned here refers to the situation where the direction of the line connecting the first clamping position 61 and the second clamping position 62 coincides with the radial direction of the rotating sample disk 12 when the clamping position and the sample well 1211 are located at the same height. Of course, during the actual sample exchange process, the clamping position is located above the sample well 1211.

[0079] The two clamping positions can respectively correspond to the positions of two adjacent circles of sample holes 1211. For example, the second clamping position 62 corresponds to the sample holes 1211 of the first circle 121, and the first clamping position 61 corresponds to the sample holes 1211 of the second circle 122. By rotating the rotating sample disk 12, the second clamping position 62 can correspond to any sample hole 1211 of the first circle 121, and the first clamping position 61 can correspond to any sample hole 1211 of the second circle 122.

[0080] Optionally, the clamping assembly further includes a mobile driver 7 for driving the clamping driver 5 and the two clamping jaws 6 to move in the first direction. Optionally, the mobile driver 7 is used to drive the clamping driver 5 and the two clamping jaws 6 to move radially of the rotating sample disk 12, and the two clamping positions are sequentially arranged along the radial direction of the rotating sample disk 12.

[0081] Optionally, the movable drive member 7 is a movable cylinder, which also has only two stop points for precise positioning, namely, the two ends of the drive stroke. Therefore, when the movable drive member 7 reaches one end of the drive stroke, the two clamping positions correspond to the positions on the first circle 121 and the second circle 122, respectively. When the movable drive member 7 reaches the other end of the drive stroke, the two clamping positions correspond to the positions on the third circle 123 and the fourth circle 124, respectively. For example, when the movable drive member 7 reaches one end of the drive stroke, the second clamping position 62 corresponds to the sample wells 1211 of the first circle 121, that is, the second clamping position 62 is located directly above the sample wells 1211 of the first circle 121, and the first clamping position 61 corresponds to the sample wells 1211 of the second circle 122, that is, the first clamping position 61 is located directly above the sample wells 1211 of the second circle 122. When the mobile driving member 7 moves to the other end of the driving stroke, the second clamping position 62 corresponds to the sample hole 1211 of the third circle 123, that is, the second clamping position 62 is located directly above the sample hole 1211 of the third circle 123, and the first clamping position 61 corresponds to the sample hole 1211 of the fourth circle 124, that is, the first clamping position 61 is located directly above the sample hole 1211 of the fourth circle 124.

[0082] Therefore, to ensure the accuracy of the aforementioned position correspondence, the radial distance between the first circle 121 and the second circle 122 must be equal to the distance between the two clamping positions, and the radial distance between the third circle 123 and the fourth circle 124 must also be equal to the distance between the two clamping positions. Furthermore, the driving stroke of the movable driving member 7 must be equal to the radial distance between the first circle 121 and the third circle 123. Correspondingly, the driving stroke of the movable driving member 7 must also be equal to the radial distance between the second circle 122 and the fourth circle 124.

[0083] In order to achieve Figure 4 and Figure 5 As shown, one of the two clamping positions can correspond vertically to one of the two accommodating spaces, and the other of the two clamping positions can correspond vertically to the other of the two accommodating spaces. Specifically, the first clamping position 61 can be precisely located above the first accommodating space 101, and the second clamping position 62 can be precisely located above the second accommodating space 102. That is, when the movable drive member 7 is in the extended state, the first clamping position 61 is precisely located above the first accommodating space 101, and when the movable drive member 7 is in the retracted state, the second clamping position 62 is precisely located above the second accommodating space 102.

[0084] In order to achieve the above-mentioned precise alignment and ensure high-precision position correspondence between the clamping assembly and the double-tube sample transfer component 1 when changing samples, optionally, the distance between the two clamping positions is d, and the length of the driving stroke of the mobile driving component 7 is s, then the distance between the first accommodating space 101 and the second accommodating space 102 needs to be sd.

[0085] The sample tubes 100 that have been tested are placed back to their original positions on the rotating sample disk 12, which facilitates sample traceability and is easy for staff to operate. In order to ensure that the sample tubes 100 that have been tested can be placed back to their original positions on the rotating sample disk 12, the control method of the one-step access and placement dual-tube sampling system needs to meet the principle of alternating sampling of odd and even circles. Odd circles include the first circle 121 and the third circle 123, and even circles include the second circle 122 and the fourth circle 124. Sample tubes 100 with odd circles can only correspond to the second clamping position 62 of the clamping jaw 6, and sample tubes 100 with even circles can only correspond to the first clamping position 61 of the clamping jaw 6.

[0086] The following example illustrates how the aforementioned control method achieves the return of tested sample tubes 100 to their original positions on the rotating sample disk 12. Initially, the gripper 6 simultaneously grips an odd-numbered sample tube 100 and an even-numbered sample tube 100, with the odd-numbered sample tube 100 positioned at the second clamping position 62 and the even-numbered sample tube 100 positioned at the first clamping position 61. The gripper 6 then docks with the dual-tube sample transfer unit 1 in response to the vertical drive 13. The odd-numbered sample tube 100 at the second clamping position 62 is placed in the second accommodating space 102, while the even-numbered sample tube 100 at the first clamping position 61 is placed in the first accommodating space 101. The dual-tube sample transfer unit 1 is then driven by the transfer drive 2 to position the first accommodating space 101 at the first position, and the even-numbered sample tube 100 in the first accommodating space 101 is placed into the sample port. After the even-numbered sample tubes 100 are tested, the even-numbered sample tubes 100 return to the first accommodating space 101. The first hook driver 3 drives the first hook 4 to position the second accommodating space 102 at the first position. The odd-numbered sample tubes 100 in the second accommodating space 102 are placed in the sample port. The double-tube sample transfer unit 1 then moves to a sample exchange position with the clamp 6. The clamp 6 clamps the even-numbered sample tubes 100 in the first accommodating space 101 and places them in the first clamping position 61. The clamp 6 returns to the rotating sample disk 12. The first clamping position 61 corresponds to the even-numbered sample hole 1211. By coordinating the rotation of the rotating sample disk 12, the even-numbered sample tubes 100 can be placed back to their original even-numbered sample holes 1211, i.e., back to their original positions. Then, a new sample tube 100 with an even number of turns is clamped at the first clamping position 61 of the clamping jaw 6 and placed accordingly in the first accommodating space 101 of the double-tube sample transfer unit 1. At this point, the sample tube 100 with an odd number of turns that just entered the sample port has been tested. The second accommodating space 102 of the double-tube sample transfer unit 1 can then retrieve the tested sample tube 100 with an odd number of turns that popped out of the sample port and place the new sample tube 100 with an even number of turns in the first accommodating space 101 into the sample port. Thus, according to the above method, and by alternately sending the sample tubes 100 with odd and even turns 100 for testing, it can be ensured that each tested sample tube 100 returns to its original position.

[0087] When the inspection process does not follow the principle of alternating inspection of odd and even circles or the staff makes a manual operation error, it is necessary to adjust and remedy it. Figure 6As shown, the first clamping position 61 can also correspond to the second accommodating space 102, and the second clamping position 62 can also correspond to the first accommodating space 101. In this way, if there are individual sample tubes 100 that have been tested in the second accommodating space 102 and are sample tubes 100 with an even number of turns, the clamping jaws 6 can clamp the sample tube 100 at the first clamping position 61. Since the first clamping position 61 corresponds to an even number of turns, the sample tube 100 that has been tested with an even number of turns can be returned to its original position.

[0088] How can we ensure that the first clamping position 61 also corresponds to the second accommodating space 102, and vice versa? Certain dimensional requirements must be met, and another set of hook components, namely the second hook driver 8 and the second hook member 9, must be provided. These will be described in detail below.

[0089] Optionally, the distance d between the two clamping positions and the length s of the driving stroke of the movable driving member 7 satisfy: s = 2d, that is, the distance between the first clamping position 61 and the second clamping position 62 is equal to the distance between the first accommodating space 101 and the second accommodating space 102. It should be noted that when the distance between two spaces is referred to, it refers to the distance between the centers of the sample tubes 100 when both spaces accommodate the sample tubes 100.

[0090] Optionally, the driving assembly also includes another set of hook assemblies, namely a second hook driving member 8 and a second hook member 9. The second hook driving member 8 can drive the second hook member 9 to block the transmission driving member 2 from driving the movement of the double-tube sample transmitting member 1, so that any clamping position can correspond to any accommodating space.

[0091] The second stop hook 9 is located at one end of the transmission drive 2 close to the clamp 6. When the clamping assembly and the double-tube sample transfer unit 1 are located at the same position as Figure 5 When the corresponding position is shown, the second hook driving member 8 drives the second hook member 9 to push the double-tube sample transfer member 1 to the left, that is, to move the sample port to a suitable distance, and the sample can be obtained. Figure 6 The corresponding positions shown.

[0092] Optionally, the second hook drive 8 is also a hook cylinder, that is, the second hook drive 8 also has only two stop positions where it can achieve precise positioning, namely, the two ends of the driving stroke. Therefore, when the second hook drive 8 is executed to one end of the driving stroke, the second hook member 9 is just located at a position where it does not block the transmission drive 2 from driving the double-tube sample transfer 1. When the second hook drive 8 is executed to the other end of the driving stroke, the second hook member 9 is just located at a position where it blocks the transmission drive 2 from driving the double-tube sample transfer 1. Accordingly, the second hook member 9 just pushes the double-tube sample transfer 1 to move to the position as shown in FIG. Figure 6As shown, the first accommodating space 101 is located below the second clamping position 62, and since the distance between the first clamping position 61 and the second clamping position 62 is equal to the distance between the first accommodating space 101 and the second accommodating space 102, the second accommodating space 102 is just located below the first clamping position 61.

[0093] Optionally, the second hook driving member 8 can drive the second hook member 9 to move in the first direction. Optionally, the driving stroke of the second hook driving member 8 is equal to the distance d between the two clamping positions, that is, when the second hook driving member 8 reaches one end of the driving stroke, the second hook member 9 is exactly at a position where it does not block the transmission driving member 2 from driving the double-tube sample transmission member 1.

[0094] like Figure 7 and Figure 8 As described above, optionally, each accommodating space is configured to be through in the vertical direction, and the double-tube sample transfer component 1 includes a limiter 104, which can limit the sample tube 100 from entering and outputting from the upper opening of the accommodating space, that is, when the clamping position of the clamp 6 is located vertically above the accommodating space, the clamp 6 releases the sample tube 100, and the sample tube 100 can fall directly into the accommodating space from the upper opening of the accommodating space, and is restricted by the limiter 104 from escaping from the lower opening.

[0095] Optionally, the limiting member 104 has a limiting state and a non-limiting state. In the limiting state, the limiting member 104 prevents the sample tube 100 from entering or exiting the accommodating space through the lower opening. In the non-limiting state, the limiting member 104 does not prevent the sample tube 100 from entering or exiting the accommodating space through the lower opening. When exchanging samples between the dual-tube sample transfer member 1 and the clamping jaws 6, the sample tubes 100 enter and exit the accommodating space through the upper opening and must remain in the limiting state. When exchanging samples between the dual-tube sample transfer member 1 and the sample port, the sample tubes 100 enter and exit the accommodating space through the lower opening and must remain in the non-limiting state.

[0096] Optionally, the double-tube sample transmission component 1 also includes a shell 103 and an elastic component. The rotating shaft 1043 of the limiting component 104 is connected to the shell 103. The limiting component 104 can rotate around the rotating shaft 1043 to adjust to a limiting state or a non-limiting state. The elastic component is connected to both the shell 103 and the limiting component 104. The elastic component is used to make the limiting component 104 tend to be in a limiting state.

[0097] Optionally, the one-step access dual-tube sampling system further includes an ejector pin 11, which is disposed at the sample port and can press against a stopper 104 to adjust the stopper 104 to a non-stop position. Optionally, in this embodiment, the ejector pin 11 is disposed on the housing of the first gear hook driver 3 via an ejector pin 11 holder 10, and both the first gear hook driver 3 and the second gear hook driver 8 are disposed on the transmission driver 2.

[0098] Optionally, the limiting member 104 includes a pin 1041 , a rotating rod 1042 and a rotating shaft 1043 . The rotating shaft 1043 is located in the middle of the rotating rod 1042 . The pin 1041 is provided at one end of the rotating rod 1042 , and the other end corresponds to the ejector pin 11 .

[0099] It should be noted that each of the two accommodating spaces has a limiting member 104. When one accommodating space is located in the first position vertically above the sample port, the limiting member 104 of the accommodating space is just pressed by the ejector pin 11, and the limiting member 104 is adjusted to a non-limiting state. The sample tube 100 can enter and exit from the lower opening of the accommodating space, thereby realizing sample exchange between the accommodating space and the sample port.

[0100] The one-step dual-tube sampling system is provided with a dual-tube sample transfer component 1 having at least two accommodating spaces. When the dual-tube sample transfer component 1 is at the sample port, the empty accommodating space can be used to obtain the sample tube 100 output from the sample port, and then a new sample tube 100 in the other accommodating space can be input into the sample port. The sample replacement step at the sample port can be completed in one step, greatly improving the sample replacement efficiency.

[0101] Furthermore, this one-step dual-tube sample transfer system utilizes a set of retaining hooks at the sample port, namely a first retaining hook driver 3 and a first retaining hook 4, to ensure that both accommodating spaces are precisely positioned at the first position vertically above the sample port, achieving high-precision sample exchange between the dual-tube sample transfer unit 1 and the sample port. This system further enhances rotational accuracy by providing multiple circles of sample wells 1211 on the rotating sample disk 12. The provision of a double-ended clamping jaw 6 and a movable driver 7 enables precise sample exchange between the clamping jaw 6 and each of the four circles of sample wells 1211. Furthermore, by coordinating the dimensions of the rotating sample disk 12, the clamping jaw 6, the movable driver 7, and the dual-tube sample transfer unit 1, precise alignment between the two ends of the clamping jaw 6 and the two accommodating spaces of the dual-tube sample transfer unit 1 is achieved. Furthermore, by controlling the various drivers, the sample tube 100 can be returned to its original position after testing, facilitating traceability in the event of an error. Furthermore, by providing a second set of hook components, namely, a second hook driver 8 and a second hook member 9 disposed near the clamping jaw 6, precise alignment of any clamping position with any accommodating space can be achieved. This allows for adjustments and corrections in the event of an error, while still returning the sample tube 100 to its original position after testing. This one-step access dual-tube sample injection system enables high-precision control of every step in the sample delivery and return process, thus meeting the high-precision requirements of nuclear magnetic resonance equipment for sample injection systems.

[0102] This embodiment also provides a nuclear magnetic resonance (NMR) device, including the aforementioned one-step dual-tube sample introduction system. The NMR device comprises a dual-tube sample transfer unit 1 with at least two accommodating spaces. When the dual-tube sample transfer unit 1 is at the sample port, it can utilize the empty accommodating space to retrieve the sample tube 100 output from the sample port, and then transfer a new sample tube 100 from the other accommodating space into the sample port. This completes the sample exchange step at the sample port in one go, significantly improving sample exchange efficiency. The NMR device's sample introduction system also utilizes a set of retaining hook assemblies, namely a first retaining hook drive 3 and a first retaining hook 4, at the sample port to ensure that both accommodating spaces are precisely positioned at a first position vertically above the sample port, achieving high-precision sample exchange requirements between the dual-tube sample transfer unit 1 and the sample port. The one-step dual-tube sample introduction system further enhances rotational accuracy by providing multiple circles of sample wells 1211 on the rotating sample disk 12. Furthermore, the provision of a double-headed clamp 6 and a movable drive 7 enables precise sample exchange between the clamp 6 and each of the four circles of sample wells 1211. Furthermore, by coordinating the dimensions of the rotating sample disk 12, the clamping jaws 6, the movable drive member 7, and the double-tube sample transfer member 1, precise alignment between the two ends of the clamping jaws 6 and the two accommodating spaces of the double-tube sample transfer member 1 is achieved. Furthermore, by controlling each drive member, the sample tube 100 can be returned to its original position after testing, making full preparations for tracing back to the source when an error occurs. Furthermore, by providing a second set of hook components, namely, a second hook drive member 8 and a second hook member 9 provided near the clamping jaws 6, precise alignment between any clamping position and any accommodating space can be achieved, so that adjustments and remedies can be made when an error occurs, and the sample tube 100 can still be returned to its original position after testing. This one-step pick-and-place double-tube sampling system can achieve high-precision control of each link in the sample delivery and return process, thereby meeting the high-precision requirements of the nuclear magnetic resonance equipment for the sampling system.

[0103] Obviously, the above embodiments of the present invention are merely examples for the purpose of clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Those skilled in the art will appreciate that other variations or modifications can be made based on the above description. It is not necessary and impossible to enumerate all embodiments here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the claims of the present invention.

Claims

1. One-step access dual-tube injection system, characterized by: include: A double-tube sample transfer component (1), the double-tube sample transfer component (1) having at least two accommodating spaces, each of the accommodating spaces being capable of accommodating a sample tube (100); A driving assembly is provided, wherein the driving assembly is capable of driving the double-tube sample transfer component (1) to and from a sampling position and a sample port, so that the sample tube (100) at the sampling position can be placed in the empty accommodating space, and the sample tube (100) in the other accommodating space can be placed in the sampling position, and the sample tube (100) at the sample port can be placed in the empty accommodating space, and the sample tube (100) in the other accommodating space can be placed in the sample port.

2. The one-step pick-and-place double-tube sampling system according to claim 1, characterized in that: The driving assembly includes a transmission driving member (2), and the transmission driving member (2) is used to drive the double-tube sample transmission member (1) to move, and the movement trajectories of the centers of at least two of the accommodating spaces are located on the same straight line, and the first position above the sample port and the sampling position are both located on the movement trajectory of the center of the accommodating space.

3. The one-step take-and-place double-tube sampling system according to claim 2, characterized in that: The accommodating space comprises a first accommodating space (101) and a second accommodating space (102); when the double-tube sample transfer component (1) moves toward the first position, the moving direction is a first direction; the first accommodating space (101) and the second accommodating space (102) are arranged in sequence along the first direction; and the transmission driving component (2) is capable of driving the double-tube sample transfer component (1) to move so that the first accommodating space (101) is located at the first position.

4. The one-step take-and-place double-tube sampling system according to claim 3, characterized in that: The driving assembly further comprises a first hook driving member (3) and a first hook member (4), wherein the first hook driving member (3) is capable of driving the first hook member (4) to block the transmission driving member (2) from driving the movement of the double-tube sample transmitting member (1), so that the second accommodating space (102) is located at the first position.

5. The one-step take-and-place double-tube sampling system according to claim 4, characterized in that: When the transmission driving member (2) reaches one end of the driving stroke, the first accommodating space (101) is located at the first position; And / or, when the first gear hook driving member (3) reaches one end of the driving stroke, the second accommodating space (102) is located at the first position; And / or, the other end of the driving stroke of the first hook driving member (3) is located at the first position corresponding to the first accommodating space (101); And / or, the distance between the first accommodating space (101) and the second accommodating space (102) is equal to the driving stroke of the first gear hook driving member (3).

6. The one-step take-and-place double-tube sampling system according to claim 3, characterized in that: The invention also includes a clamping assembly, which includes a clamping drive (5) and two clamping jaws (6). The clamping drive (5) is used to drive the two clamping jaws (6) to move closer to each other to clamp the sample tube (100), or to move away from each other to release the sample tube (100).

7. The one-step take-and-place double-tube sampling system according to claim 6, characterized in that: The two clamping jaws (6) have two clamping positions sequentially arranged along the first direction, and each of the clamping positions can accommodate one sample tube (100).

8. The one-step take-and-place double-tube sampling system according to claim 7, characterized in that: The clamping assembly further comprises a moving drive member (7), and the moving drive member (7) is used to drive the clamping drive member (5) and the two clamping claws (6) to move along the first direction.

9. The one-step take-and-place double-tube sampling system according to claim 8, characterized in that: The distance between the two clamping positions is d, the length of the driving stroke of the movable driving member (7) is s, and the distance between the first accommodating space (101) and the second accommodating space (102) is sd.

10. The one-step take-and-place double-tube sampling system according to claim 9, characterized in that: The distance d between the two clamping positions and the length s of the driving stroke of the moving driving member (7) satisfy: s=2d.

11. The one-step pick-and-place double-tube sampling system according to claim 10, characterized in that: The driving assembly further comprises a second hook driving member (8) and a second hook member (9), wherein the second hook driving member (8) can drive the second hook member (9) to block the transmission driving member (2) from driving the movement of the double-tube sample transmitting member (1), so that any of the clamping positions can correspond to any of the accommodating spaces.

12. The one-step pick-and-place double-tube sampling system according to claim 11, characterized in that: The second gear hook driving member (8) can drive the second gear hook member (9) to move along the first direction, and the driving stroke of the second gear hook driving member (8) is equal to the distance d between the two clamping positions.

13. The one-step take-and-place double-tube sampling system according to any one of claims 1 to 12, characterized in that: Each of the accommodating spaces is configured to be through in a vertical direction, and the double-tube sample transfer component (1) includes a limiting component (104), and the limiting component (104) can limit the sample tube (100) from entering and exiting from the upper opening of the accommodating space.

14. The one-step pick-and-place double-tube sampling system according to claim 13, characterized in that: The limiting member (104) has a limiting state and a non-limiting state. In the limiting state, the limiting member (104) limits the sample tube (100) from entering and exiting from the lower opening of the accommodating space. In the non-limiting state, the limiting member (104) cannot limit the sample tube (100) from entering and exiting from the lower opening.

15. The one-step pick-and-place double-tube sampling system according to claim 14, characterized in that: The double-tube sample transmission component (1) further includes a housing (103) and an elastic component. The rotation axis (1043) of the limiting component (104) is connected to the housing (103). The limiting component (104) can rotate around the rotation axis (1043) to adjust to the limiting state or the non-limiting state. The elastic component is connected to both the housing (103) and the limiting component (104). The elastic component is used to make the limiting component (104) tend to be in the limiting state.

16. The one-step take-and-place double-tube sampling system according to claim 15, characterized in that: It also includes a thimble (11), which is arranged at the sample port and can press the limiting member (104) to adjust the limiting member (104) to the non-limiting state.

17. The one-step take-and-place double-tube sampling system according to claim 8, characterized in that: The invention also includes a rotating sample disk (12), wherein the rotating sample disk (12) has multiple circles of sample holes (1211), each circle of the sample holes (1211) includes multiple sample holes (1211) arranged at circumferential intervals, and the centers of the virtual circles of the multiple circles of the sample holes (1211) coincide with the rotation center of the rotating sample disk (12), and the sample tube (100) is placed in the sample hole (1211).

18. The one-step take-and-place double-tube sampling system according to claim 17, characterized in that: The moving drive member (7) is used to drive the clamping drive member (5) and the two clamping claws (6) to move along the radial direction of the rotating sample disk (12), and the two clamping positions are sequentially arranged along the radial direction of the rotating sample disk (12).

19. The one-step take-and-place double-tube sampling system according to claim 17, characterized in that: The rotating sample disk (12) has four circles of sample holes (1211). Along the radial direction of the rotating sample disk (12), the four circles of sample holes (1211) are a first circle (121), a second circle (122), a third circle (123) and a fourth circle (124). When the movable driving member (7) is executed to one end of the driving stroke, the two clamping positions respectively correspond to the position on the first circle (121) and the position on the second circle (122). When the movable driving member (7) is executed to the other end of the driving stroke, the two clamping positions respectively correspond to the position on the third circle (123) and the position on the fourth circle (124).

20. Nuclear magnetic resonance equipment, characterized in that The invention comprises a one-step take-and-place double-tube sampling system as described in any one of claims 1 to 19.

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