Automatic radioactive medicine split charging and injecting system and working method

Abstract

The invention discloses an automatic radioactive drug split charging and injection system and a working method. The system comprises a shell, a control structure, a stock solution treatment structure, a fluid control structure, a waste liquid management structure and a moving structure. The control structure is connected with other structures and assembled on the shell, and the shell is assembled on the moving structure. The control structure is used for operating and controlling the stock solution treatment structure, the fluid control structure and the waste liquid management structure and immediately stopping corresponding structure functions in an emergency; the stock solution treatment structure is used for storing and treating starting, closing and needle inserting operations of radiopharmaceutical stock solution; and the fluid control structure is used for accurately controlling the waste liquid management structure in the extraction and injection process of the radiopharmaceutical stock solution, and is used for collecting and storing waste liquid generated in the extraction and injection process. By implementing the system disclosed by the invention, the operation safety and accuracy can be improved, the cost can be reduced, and the medicine utilization rate can be improved.

Description

Technical Field

[0001] The present invention relates to the technical field of automated equipment, and in particular to an automatic radiopharmaceutical subpackaging and injection system and a working method. Background Art

[0002] In the field of nuclear medicine diagnosis, current operating methods primarily rely on traditional manual operations for the packaging and injection of radioactive drugs. This method has significant limitations and risks: First, manual operation leads to a greater risk of radiation exposure, posing a potential threat to the health of operators; second, because manual operation cannot ensure high precision, the packaging dose and injection accuracy have large errors, which not only affects the consistency of treatment effects but also may pose additional risks to patients. In addition, although some hospitals have introduced imported automatic packaging and injection equipment to attempt to address these issues, these devices are expensive, with high operating and maintenance costs. In actual use, there are still problems with high local radiation exposure and waste during the packaging process, which fails to effectively improve drug utilization.

[0003] Another significant drawback of existing technology is inadequate radiation protection. Especially when handling high-dose radioactive raw liquids, traditional equipment requires manual opening of the shielding tank and insertion of the needle. This process offers limited protection and increases the risk of radiation exposure for operators. Furthermore, current equipment often utilizes one-way flow lines, which often necessitates disposing of the dispensed liquid as waste in the event of an abnormality. This further reduces drug utilization and increases medical costs.

[0004] Therefore, it is necessary to design a new system that can not only improve operational safety and accuracy, but also reduce costs and increase drug utilization. Summary of the Invention

[0005] The purpose of the present invention is to overcome the defects of the prior art and provide a radiopharmaceutical automatic subpackaging and injection system and a working method.

[0006] To solve the above technical problems, the present invention is achieved through the following technical solutions: providing an automatic sub-packaging and injection system for radiopharmaceuticals, comprising: a housing, a control structure, a stock solution processing structure, a fluid control structure, a waste liquid management structure, and a mobile structure; the control structure is connected to the stock solution processing structure, the fluid control structure, and the waste liquid management structure, respectively; the control structure, the stock solution processing structure, the fluid control structure, and the waste liquid management structure are respectively assembled on the housing, and the housing is assembled on the mobile structure;

[0007] The control structure is used for controlling the operation of the raw liquid processing structure, the fluid control structure, and the waste liquid management structure, and for immediately stopping the corresponding structural functions in an emergency;

[0008] The stock solution processing structure is used for storing and processing the opening, closing and needle insertion operations of the radiopharmaceutical stock solution;

[0009] The fluid control structure is used to accurately control the extraction and injection process of radiopharmaceutical stock solution.

[0010] The waste liquid management structure is used to collect and store waste liquid generated during the extraction and injection processes.

[0011] Its further technical solution is: the raw liquid processing structure includes a raw liquid shielding tank and a tank inlet assembly; the raw liquid shielding tank is placed in the tank inlet assembly.

[0012] A further technical solution is as follows: the raw liquid processing structure includes a pin assembly and a cover opening assembly, and the pin assembly and the cover opening assembly are assembled in the shell.

[0013] Its further technical solution is: the fluid control structure includes a single three-way valve assembly, a liquid medicine pump, a double three-way valve assembly, an injection pump and a sub-packaging pipeline; the sub-packaging pipeline is respectively installed in the single three-way valve assembly, the liquid medicine pump, the double three-way valve assembly and the injection pump.

[0014] A further technical solution is as follows: the fluid control structure includes a dose calibrator, and the subpackaging pipeline is installed in the dose calibrator.

[0015] Its further technical solution is: the waste liquid management structure includes a waste liquid discharge port and a waste liquid bottle; the waste liquid discharge port is connected to the waste liquid bottle; and the waste liquid discharge port is connected to the subpackaging pipeline.

[0016] A further technical solution is as follows: a waste liquid shielding chamber is provided on the side of the shell, and the waste liquid bottle is placed in the waste liquid shielding chamber.

[0017] A further technical solution is as follows: a sliding door is provided on the shell; the control unit includes an operating screen, the operating screen is placed on the sliding door, and a lead shielding room is provided in the shell.

[0018] A further technical solution is: the movable structure includes a roller, and the roller is assembled below the shell.

[0019] In addition, in order to overcome the defects of the prior art, the present invention further provides a working method of the above-mentioned radiopharmaceutical automatic subpackaging and injection system, which is characterized by comprising:

[0020] The control structure starts and guides the raw liquid processing structure to make the raw liquid shielding tank enter the specified position and complete the pin insertion;

[0021] The fluid control structure extracts saline and radioactive drugs, performs dose calibration and then performs precise injection;

[0022] If waste liquid is generated, it will be automatically collected and stored by the waste liquid management structure;

[0023] After all injections are completed, the lines are cleaned and the remaining drug is returned to the stock solution shielding tank and removed after safe decay.

[0024] The beneficial effects of the present invention compared to the prior art are as follows: the present invention improves the safety and accuracy of operation by integrating the control structure, the stock liquid processing structure, the fluid control structure and the waste liquid management structure into a mobile shell, while reducing costs and increasing drug utilization. Specifically, the control structure centrally controls each functional module and can immediately stop the system in an emergency, ensuring the safety of the operator; the stock liquid processing structure is responsible for key operations such as storage, opening, closing and insertion of radioactive drug stock liquid, reducing the possibility of human error; the fluid control structure ensures precise control of the extraction and injection process of the radioactive drug stock liquid, thereby improving the accuracy of drug use; the waste liquid management structure effectively collects and stores waste liquid to prevent environmental pollution, and also reduces overall costs by recycling reusable components in the waste liquid. These design features work together to not only improve the safety and efficiency of the system, but also optimize the use of resources, making the entire treatment process more environmentally friendly and cost-effective.

[0025] The present invention will be further described below with reference to the accompanying drawings and specific embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0027] Figure 1 A schematic diagram of the three-dimensional structure of an automatic radiopharmaceutical subpackaging and injection system provided by an embodiment of the present invention;

[0028] Figure 2 A schematic diagram of the right side structure of an automatic radiopharmaceutical subpackaging and injection system provided by an embodiment of the present invention;

[0029] Figure 3 A left-side structural schematic diagram of an automatic radiopharmaceutical subpackaging and injection system provided by an embodiment of the present invention;

[0030] Figure 4 A schematic diagram of the main structure of a radiopharmaceutical automatic subpackaging and injection system provided by an embodiment of the present invention;

[0031] Figure 5 A schematic rear structural diagram of an automatic radiopharmaceutical subpackaging and injection system provided by an embodiment of the present invention;

[0032] Figure 6 A schematic top view of a radiopharmaceutical automatic subpackaging and injection system provided by an embodiment of the present invention;

[0033] Description of the symbols in the figure:

[0034] 1. Operation screen; 2. Emergency stop button; 3. Printer; 4. Raw liquid shielding tank; 5. Tank inlet assembly; 6. Single three-way valve assembly; 7. Liquid pump; 8. Double three-way valve assembly; 9. Syringe pump; 10. Dose calibrator; 11. Waste liquid outlet; 12. Waste liquid bottle; 13. Pin assembly; 14. Lid opening assembly; 15. Lead shielding chamber; 16. Shell; 17. Sliding door; 18. Packaging pipeline; 19. Hanger; 20. Roller; 21. Waste liquid shielding chamber 21. DETAILED DESCRIPTION

[0035] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0036] It will be understood that when used in this specification and the appended claims, the terms “comprises” and “comprising” indicate the presence of described features, integers, steps, operations, elements and / or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components and / or groups thereof.

[0037] It should also be understood that the terminology used in this specification is for the purpose of describing particular embodiments only and is not intended to limit the present invention. As used in the specification and appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms unless the context clearly indicates otherwise.

[0038] It should be further understood that the term "and / or" used in the present description and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

[0039] Currently, the field of nuclear medicine diagnosis mainly relies on manual operations for the packaging and injection of radioactive drugs. This method not only exposes operators to a high risk of radiation exposure, but also makes it difficult to ensure the consistency of dosage and injection accuracy, affecting the treatment effect and potentially bringing additional risks to patients. Although some hospitals have introduced expensive imported automatic equipment in an attempt to solve these problems, these devices still have shortcomings in terms of cost, local radiation exposure control, and drug utilization. In addition, when handling high-dose radiation raw liquid, the existing technology lacks effective radiation protection measures and one-way flow pipeline design, which can easily lead to liquid waste in abnormal situations, further increasing medical costs and limiting the improvement of drug utilization.

[0040] To this end, an embodiment of the present invention provides an automatic radiopharmaceutical subpackaging and injection system, which can improve operational safety and accuracy while reducing costs and improving drug utilization.

[0041] Specifically, this automated radiopharmaceutical dispensing and injection system integrates control structures, bulk liquid processing, fluid control, and waste liquid management within a mobile housing 16, enabling automated radiopharmaceutical processing, precise extraction and injection, and safe waste liquid disposal. Its design utilizes shielded tanks and a shielded room to effectively reduce radiation risks. Precisely controlled components ensure accurate drug dosage and minimize human error. A waste liquid management system avoids environmental pollution and improves resource utilization. Furthermore, the system's modular design and lead shielding enhance operational safety and convenience while extending the equipment's lifespan and reducing overall costs. The highly automated process reduces manual intervention, further ensuring operator safety and improving work efficiency while also optimizing drug utilization.

[0042] In order to better understand the above technical solution, the above technical solution will be described in detail below with reference to the accompanying drawings and specific implementation methods.

[0043] See also Figures 1 to 6 A radiopharmaceutical automatic sub-packaging and injection system includes: a housing 16, a control structure, a stock solution processing structure, a fluid control structure, a waste liquid management structure, and a mobile structure; the control structure is connected to the stock solution processing structure, the fluid control structure, and the waste liquid management structure respectively; the control structure, the stock solution processing structure, the fluid control structure, and the waste liquid management structure are respectively assembled on the housing 16, and the housing 16 is assembled on the mobile structure;

[0044] Control structure, used for the operation control of raw liquid processing structure, fluid control structure, waste liquid management structure and immediate stop of corresponding structural functions in emergency;

[0045] The raw liquid processing structure is used to store and handle the opening, closing and needle insertion operations of the radioactive drug raw liquid; the fluid control structure is used to extract the radioactive drug raw liquid and accurately control the injection process; the waste liquid management structure is used to collect and store the waste liquid generated during the extraction and injection process.

[0046] In this embodiment, all components are assembled in the housing 16 to form an integral unit, and the housing 16 itself is assembled on a mobile structure with rollers 20, so that the entire device can be easily moved.

[0047] As the brain of the system, the control structure is not only responsible for the operational control of the raw liquid processing structure, fluid control structure and waste liquid management structure, but can also immediately stop the corresponding functions in an emergency to ensure safety.

[0048] The raw liquid handling structure includes a raw liquid shielding tank 4, a tank inlet assembly 5, a pin insertion assembly 13, and a lid opening assembly 14. It is used to safely store the radiopharmaceutical raw liquid and perform operations such as opening, closing, and pin insertion. The shielding design reduces the risk of radiation exposure to operators.

[0049] The fluid control structure consists of a single three-way valve assembly 6, a liquid medicine pump 7, a double three-way valve assembly 8, an injection pump 9, and a dose calibrator 10. This allows for precise extraction and injection control of the radiopharmaceutical solution. This ensures accurate and efficient drug use while reducing waste.

[0050] The waste liquid management structure includes a waste liquid outlet 11 and a waste liquid bottle 12, which are specially designed to collect and store waste liquid generated during the injection process to prevent environmental pollution and protect the safety of operators.

[0051] First, the system is activated via the control panel 1. The stock solution shielding tank 4 is moved to the designated position and the needle is inserted. Subsequently, the drug pump 7 pumps saline into the dispensing line 18 for line integrity testing. The patient is then connected to the device for precise radiopharmaceutical injection. Any waste liquid is automatically discharged into the waste liquid bottle 12. After the injection is complete, the system automatically cleans the line and returns the remaining drug to the stock solution shielding tank 4 for decay processing.

[0052] This system's design achieves a high degree of automation, reducing manual intervention and effectively lowering the operator's radiation exposure risk. Precision control improves drug utilization, while the high domestic component count effectively controls equipment costs, facilitating widespread adoption. Furthermore, the design of the lead shielding room 15 further ensures a safe operating environment. In summary, this automated radiopharmaceutical dispensing and injection system significantly improves work efficiency and safety, possessing significant practical value.

[0053] In one embodiment, see Figure 1 and Figure 3 The above-mentioned raw liquid processing structure includes a raw liquid shielding tank 4 and a tank inlet assembly 5; the raw liquid shielding tank 4 is placed in the tank inlet assembly 5.

[0054] In one embodiment, see Figure 3 The above-mentioned raw liquid processing structure includes a pin assembly 13 and a cover opening assembly 14 , and the pin assembly 13 and the cover opening assembly 14 are assembled in the shell 16 .

[0055] In a specific embodiment, according to Figure 1 The illustrated automated radiopharmaceutical dispensing and injection system comprises two key components for handling bulk liquid: a bulk liquid shielding tank 4 and an inlet tank assembly 5. The bulk liquid shielding tank 4 is specifically designed to store bulk radiopharmaceutical liquid and is constructed to effectively minimize radiation leakage and ensure operator safety. The shielding tank is carefully positioned within the inlet tank assembly 5, which is responsible for safely and accurately delivering the bulk liquid shielding tank 4 to a designated location in the system for subsequent processing.

[0056] An opening is provided on one side of the shell 16, and the tank inlet assembly 5 is placed at the opening. The tank inlet assembly 5 is provided with a slide rail and a mounting bracket. The mounting bracket is provided with a mounting groove for placing the raw liquid shielding tank 4. The slide rail is provided below the mounting bracket and can slide along the opening to facilitate pushing the raw liquid shielding tank 4 into the shell 16.

[0057] Further references Figure 3 In another embodiment, the raw liquid processing structure further includes a needle assembly 13 and a lid opening assembly 14, both of which are also assembled within the housing 16. The needle assembly 13 is designed to accurately insert a needle into the raw liquid shielding tank 4 when needed to extract the radioactive drug; at the same time, it can also accurately remove the needle according to instructions after completing the task, ensuring safety during operation. The lid opening assembly 14 is responsible for opening and closing the lid of the raw liquid shielding tank 4, ensuring that the radioactive material in the tank is properly sealed when not in use to avoid the risk of leakage.

[0058] The integrated design of these two components (pin assembly 13 and lid opening assembly 14) with the housing 16 not only improves the efficiency of the entire system but also significantly reduces the need for manual intervention through automated operation, further reducing the risk of operator exposure to radiation. Furthermore, the sophisticated design and efficient operation of these components are key factors in achieving the high precision and safety of the automated radiopharmaceutical dispensing and injection system.

[0059] In summary, the above-described embodiments demonstrate that the various components of the bulk liquid processing structure (including bulk liquid shielding tank 4, tank inlet assembly 5, pin assembly 13, and lid opening assembly 14) are meticulously designed and arranged to ensure efficient operation of the entire system and operator safety. The close coordination of these components ensures both precise and safe automated radiopharmaceutical dispensing and injection, demonstrating the key innovations and technical advantages of this invention.

[0060] In one embodiment, see Figure 6 The above-mentioned fluid control structure includes a single three-way valve assembly 6, a liquid medicine pump 7, a double three-way valve assembly 8, an injection pump 9 and a sub-packaging pipeline 18; the sub-packaging pipeline 18 is respectively installed in the single three-way valve assembly 6, the liquid medicine pump 7, the double three-way valve assembly 8, and the injection pump 9.

[0061] In this embodiment, the single three-way valve assembly 6 is a key component for directing liquid flow. It selectively directs the liquid along different paths, ensuring the correct flow direction within the system. Next, the liquid is propelled by the drug pump 7, which primarily provides power to move the drug throughout the system, and can adjust the flow rate as needed.

[0062] Subsequently, the liquid reaches the double three-way valve assembly 8, which is a more complex valve system that can more flexibly control the flow path and direction of the fluid. Compared with the single three-way valve, it can provide more fluid path options, increasing the flexibility and functionality of the system.

[0063] Next, the liquid enters the syringe pump 9, which is designed to precisely control the amount of liquid injected. The syringe pump 9 can very accurately measure and deliver a specific volume of liquid, which is crucial for ensuring the accuracy of the drug dosage.

[0064] Finally, all of these components are connected to the dispensing pipeline 18, which runs through the single three-way valve assembly 6, the drug liquid pump 7, the double three-way valve assembly 8, and the syringe pump 9, fulfilling the function of liquid transportation. The design of the dispensing pipeline 18 must take into account chemical resistance, biocompatibility, and safety to ensure that the drug is not contaminated or lost during transportation.

[0065] In one embodiment, see Figure 6 The above-mentioned fluid control structure includes a dose calibrator 10, and a filling pipeline 18 is installed in the dose calibrator 10.

[0066] Specifically, the dose calibrator 10 also houses a dispensing line 18. The primary function of the dose calibrator 10 is to perform final calibration and verification of the medication dose to be dispensed to the patient, ensuring both accuracy and safety. Using the dose calibrator 10 further improves the accuracy of the entire system's medication dosage control, reduces errors, and ensures the safety and effectiveness of medication for patients.

[0067] In summary, based on Figure 6 The two embodiments of the fluid control structure include the entire process from liquid guidance to precise metering to final dose calibration. Each component plays an indispensable role in the entire fluid control system, and they work together to achieve high precision and high reliability of the radiopharmaceutical automatic filling and injection system.

[0068] In one embodiment, see Figure 2 The waste liquid management structure includes a waste liquid outlet 11 and a waste liquid bottle 12; the waste liquid outlet 11 is connected to the waste liquid bottle 12; and the waste liquid outlet 11 is connected to the sub-filling pipeline 18. The waste liquid outlet 11 is directly connected to the waste liquid bottle 12, and is used to safely transfer the waste liquid generated in the system to the waste liquid bottle 12 for collection and subsequent treatment. In addition, the waste liquid outlet 11 is also connected to the sub-filling pipeline 18, which means that any waste liquid or unwanted liquid generated during the drug distribution process can be guided to the waste liquid outlet 11 through the sub-filling pipeline 18 and finally into the waste liquid bottle 12.

[0069] In one embodiment, see Figure 2 The side of the housing 16 is provided with a waste liquid shielding chamber 21, and the waste liquid bottle 12 is placed in the waste liquid shielding chamber 21. The main purpose of this design is to provide additional safety, which is particularly important when handling waste liquid containing radioactive or other hazardous substances. The waste liquid shielding chamber 21 is typically made of a material that can effectively block radiation, such as lead, lead glass, tungsten alloy, and other high-density materials. This can minimize the impact of harmful substances that may be contained in the waste liquid on the external environment and operators.

[0070] The above design not only achieves effective management and safe storage of waste liquid, but also ensures the environmental protection and safety of the entire system. Specifically:

[0071] Connection between the waste liquid discharge port 11 and the waste liquid bottle 12: This direct connection ensures that the waste liquid can be quickly and completely discharged from the inside of the system into the waste liquid bottle 12, reducing the risk of waste liquid remaining in the system.

[0072] The connection between the waste liquid discharge port 11 and the subpackaging pipeline 18 enables any waste liquid in the subpackaging process to be promptly and effectively processed, thereby avoiding the possibility of cross contamination.

[0073] The design of the waste liquid shielding room 21 provides physical isolation for the waste liquid bottles 12. Especially when handling radioactive waste liquid, this shielding measure greatly protects the safety of operators and prevents radioactive substances from leaking into the environment.

[0074] In one embodiment, see Figure 1 The above-mentioned housing 16 is provided with a push door 17; the control unit includes an operation screen 1 and an emergency stop button 2, the operation screen 1 is placed on the push door 17, and a lead shielding room 15 is provided in the housing 16.

[0075] Housing 16 is equipped with a key operating component—a push-door 17. This push-door 17 not only provides a convenient entrance for users to access the interior of housing 16 for operations such as maintenance, inspection, or replacement of internal components, but also enhances the overall sealing and safety of the device. In particular, the operation screen 1, a key component of the control unit, is mounted on push-door 17. By placing the operation screen 1 on push-door 17, users can conveniently operate and monitor the device's status directly from the outside, obtaining necessary information or executing commands without having to open the device, greatly improving ease of use and efficiency.

[0076] Furthermore, this embodiment mentions a lead shielding chamber 15 within the housing 16. This chamber 15 is designed to provide an additional layer of safety, particularly important when the device handles radioactive materials. Lead, as a highly effective radiation shielding material, effectively blocks harmful radiation such as X-rays and gamma rays, preventing them from leaking into the external environment, thereby protecting the operator and the surrounding environment.

[0077] In addition, the emergency stop button 2 is used to stop the operation of the system in time in an emergency.

[0078] In one embodiment, see Figure 1 The moving structure includes a roller 20 , which is assembled below the housing 16 .

[0079] In this embodiment, this design allows for excellent mobility of the entire device, allowing it to be easily moved from one location to another as needed. This is particularly useful for applications requiring the device to be used in multiple locations, such as field medical services, transfers between laboratories, or rapid deployment in emergency situations. The assembly of the wheels 20 also takes into account the stability and load-bearing capacity of the device, ensuring safe and smooth movement even when loaded with heavy objects or when the device itself is heavy.

[0080] By arranging the operating screen 1 on the sliding door 17, convenient operation and monitoring functions are achieved, while the safety and sealing of the equipment are enhanced.

[0081] In response to possible radiation risks, a lead shielding room 15 is set up inside to provide effective protection measures and ensure safe operation.

[0082] The rollers 20 mounted on the bottom give the device excellent mobility, adapt to the needs of diverse application scenarios, and enhance the flexibility and applicability of the device.

[0083] In one embodiment, see Figure 4 and Figure 5 The housing 16 is provided with a hanger 19 for hanging the liquid bag. This provides a convenient and stable way to store these liquid containers. With this design, users can easily hang the liquid bag in a designated location, which not only facilitates the operation process but also optimizes space utilization.

[0084] The design of the hanger 19 takes into account various practical requirements, such as ensuring that the liquid bag is securely suspended and not prone to slipping or damage, while also facilitating installation and removal. Furthermore, a properly arranged hanger 19 helps maintain a clean and tidy work environment, improves work efficiency, and potentially reduces the risk of contamination or other safety hazards caused by improper storage.

[0085] In summary, the hanger 19 mentioned in this embodiment provides a practical hanging solution for the raw liquid bag, which not only improves the convenience of use, but also enhances the functionality and safety of the overall equipment.

[0086] The system in this embodiment is designed to automate the dispensing and injection of drugs in the field of nuclear medicine diagnostics. This system is designed to replace traditional manual operation and address the current industry needs for improved dispensing accuracy, reduced radiation exposure risks, and increased drug utilization.

[0087] In one embodiment, see Figure 1 The above-mentioned radiopharmaceutical automatic subpackaging and injection system includes a printer 3, which is connected to the control structure and can print out records and reports of each operation, which is crucial for quality control and compliance inspection.

[0088] The operator activates the system through the control panel 1 and the automatic dispensing and injection process. The tank feed assembly 5 accurately delivers the bulk solution shielding tank 4 to the designated position within the radiopharmaceutical automatic dispensing and injection system. Subsequently, the needle assembly 13 raises the tank feed assembly 5 to a predetermined height, allowing the lid opening assembly 14 to smoothly open the lid of the bulk solution shielding tank 4. The needle assembly 13 then further raises to the insertion position, completing the insertion and preparing for the subsequent steps.

[0089] The drug solution pump 7 starts working, extracting physiological saline from the outside and transferring it through the filling line 18. The injection pump 9 is responsible for pumping out the physiological saline through the filling line 18 to detect the integrity of the line. Once it is confirmed that there are no leaks or other problems, the system will connect the filling line 18 to the patient. After that, the drug solution pump 7 extracts the radioactive drug from the raw liquid shielding tank 4 and transports it to the dose calibrator 10 for activity measurement. After the measurement is completed, the injection pump 9 pumps out a precise amount of radioactive drug solution 7 to complete the injection process for the patient. This step can be repeated to support continuous filling and injection operations.

[0090] Any waste generated during treatment is collected and processed. When waste is generated, the outlet of the dispensing line 18 is relocated to the waste outlet 11, which is connected to the waste bottle 12 via a pipeline. The system automatically discharges the waste into the waste bottle 12, ensuring a safe and contaminated environment.

[0091] After all patients have completed their injections, the system enters automatic cleaning mode, flushing the dispensing line 18 with saline and recovering the remaining drug into the bulk solution shielding tank 4. Once the drug has decayed to a safe dosage range, the needle insertion assembly 13 descends, removes the needle, and returns to its initial position. The lid opening assembly 14 re-engages, replacing the lid of the bulk solution shielding tank 4 and sealing it securely. The tank inlet assembly 5 then removes the bulk solution shielding tank 4 from the system, requiring the operator to manually place it in a safe storage location.

[0092] The final step is system reset and maintenance. The operator unlocks the safety lock on the control panel 1, opens the sliding door 17, and manually removes the dispensing line 18, placing it in a designated waste collection location for subsequent cleaning or replacement. This step ensures the safety and sanitation standards of the equipment while also preparing it for the next use.

[0093] A carefully designed packaging method enables precise control of drug flow, reducing drug loss. A protective shielding design ensures safe levels of radiation exposure. Automated processes reduce manual intervention, effectively protecting the health of operators. Furthermore, a high localization rate of 95% for components keeps equipment costs manageable, facilitating widespread adoption. These improvements significantly overcome shortcomings in existing technologies and improve both efficiency and safety.

[0094] In this embodiment, the lid opening and pin insertion processes are achieved through precision mechanical components and automated control. The working principle of the lid opening component 14: the lid opening component 14 uses a ball linear guide as a guide device to ensure the accuracy and stability of the movement. The motor drives the ball screw to rotate, so that the raw liquid shielding tank cover can move linearly in the horizontal direction. When the pin assembly 13 lifts the raw liquid shielding tank to the predetermined lid opening position, the lid opening component 14 moves to the slot position of the raw liquid shielding tank cover. Subsequently, the pin assembly 13 descends to separate the tank cover from the raw liquid shielding tank. Next, the lid opening component 14 moves the raw liquid shielding tank cover horizontally to the avoidance position, completing the entire lid opening process.

[0095] The function and operation process of the pin assembly 13 are as follows: the pipeline needle is fixed at a designated position directly above the raw liquid shielding tank, and the raw liquid shielding tank is accurately delivered to a specific position inside the device by the tank inlet assembly, that is, directly above the support plate inside the pin assembly 13. The pin assembly 13 is also guided by a ball linear guide, and a motor is used to drive the ball screw to achieve linear movement of the raw liquid shielding tank in the vertical direction. In this process, the support plate of the pin assembly 13 is responsible for lifting the raw liquid shielding tank. The process includes two key positions - the first is to reach the cover opening position. After completing the cover opening action, the pin assembly 13 will continue to lift the raw liquid shielding tank to the highest point (i.e., the pin insertion position), thereby completing the pin insertion operation.

[0096] This design not only improves the accuracy and efficiency of operation, but also ensures the stability and reliability of the system. It is suitable for occasions that require high-precision operation.

[0097] The aforementioned automatic radioactive filling and injection system integrates a control structure, a bulk liquid processing structure, a fluid control structure, and a waste liquid management structure within a mobile housing 16, thereby improving operational safety and precision while reducing costs and increasing drug utilization. Specifically, the control structure centrally controls each functional module and can immediately stop the system in an emergency, ensuring operator safety. The bulk liquid processing structure is responsible for key operations such as storage, opening, closing, and needle insertion of the radioactive drug bulk liquid, reducing the possibility of human error. The fluid control structure ensures precise control of the extraction and injection process of the radioactive drug bulk liquid, thereby improving the accuracy of drug use. The waste liquid management structure effectively collects and stores waste liquid to prevent environmental pollution, while also reducing overall costs by recycling reusable components in the waste liquid. These design features work together to not only improve the safety and efficiency of the system, but also optimize resource utilization, making the entire treatment process more environmentally friendly and cost-effective.

[0098] In one embodiment, a method for operating the aforementioned radiopharmaceutical automatic dispensing and injection system is also provided, comprising:

[0099] The control structure starts and guides the raw liquid processing structure to make the raw liquid shielding tank 4 enter the specified position and complete the pin insertion;

[0100] The fluid control structure extracts saline and radioactive drugs, performs dose calibration and then performs precise injection;

[0101] If waste liquid is generated, it will be automatically collected and stored by the waste liquid management structure;

[0102] After all injections are completed, the pipeline is cleaned and the remaining medicine is returned to the original liquid shielding tank 4 and taken out after safe decay.

[0103] Specifically, the operator first activates the system via the control panel 1. Next, the canister inlet assembly 5 delivers the shielded canister containing the radiopharmaceutical concentrate to a designated location within the system. The needle assembly 13 then raises the canister inlet assembly 5 to an appropriate height, and the canister lid is opened by the lid opening assembly 14. The needle assembly 13 then continues to rise to the preset insertion position, completing the insertion process and preparing for subsequent drug extraction.

[0104] The drug solution pump 7 first draws saline solution into the dispensing line 18, while the syringe pump 9 pumps the saline solution out of the line to test its integrity. Once verified, the dispensing line 18 is connected to the patient. The drug solution pump 7 then draws the radiopharmaceutical from the bulk solution shielding tank 4 into the dispensing line 18 and delivers it to the dose calibrator 10 for activity measurement. After dose calibration, the syringe pump 9 administers the precisely measured amount of radiopharmaceutical solution to the patient, ensuring safe and effective treatment.

[0105] Any waste liquid generated during the injection process will be automatically collected. Specifically, when waste liquid is generated, the outlet of the sub-packaging pipeline 18 will be moved to the waste liquid discharge port 11, and the waste liquid will flow into the waste liquid tank through the pipeline to ensure that the waste liquid is properly handled and prevent environmental pollution.

[0106] After completing the injection for all patients, the system automatically cleans the tubing and returns the remaining medication to the stock solution shielding tank 4. Once the medication has decayed to a safe dosage range, the needle insertion assembly 13 descends to remove the needle, and the shielding tank lid is replaced. Finally, the tank inlet assembly 5 removes the stock solution shielding tank 4 from the system and is manually placed in a designated storage location.

[0107] The operator unlocks the safety lock and opens the push door 17 through the operation screen 1, removes the used subpackaging pipeline 18, and places it in a designated waste recycling location for subsequent processing or disposal.

[0108] Through the above steps, the system not only achieves the safe and accurate packaging and injection of radioactive drugs, but also effectively manages and disposes of the generated waste liquid, while ensuring the safety of equipment use and the convenience of maintenance.

[0109] It should be noted that those skilled in the art can clearly understand that the specific implementation process of the working method of the above-mentioned radiopharmaceutical automatic packaging and injection system can refer to the corresponding description in the aforementioned system embodiment. For the convenience and brevity of the description, it will not be repeated here.

[0110] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any person skilled in the art can easily conceive of various equivalent modifications or substitutions within the technical scope disclosed in the present invention, and such modifications or substitutions are intended to be within the scope of protection of the present invention. Therefore, the scope of protection of the present invention shall be subject to the scope of protection of the claims.

Claims

1. A radiopharmaceutical automatic sub-packaging and injection system, characterized in that: include: A housing, a control structure, a raw liquid processing structure, a fluid control structure, a waste liquid management structure, and a mobile structure; the control structure is connected to the raw liquid processing structure, the fluid control structure, and the waste liquid management structure respectively; the control structure, the raw liquid processing structure, the fluid control structure, and the waste liquid management structure are respectively assembled on the housing, and the housing is assembled on the mobile structure; The control structure is used for controlling the operation of the raw liquid processing structure, the fluid control structure, and the waste liquid management structure, and for immediately stopping the corresponding structural functions in an emergency; The stock solution processing structure is used for storing and processing the opening, closing and needle insertion operations of the radiopharmaceutical stock solution; The fluid control structure is used to accurately control the extraction and injection process of radiopharmaceutical stock solution. The waste liquid management structure is used to collect and store waste liquid generated during the extraction and injection processes.

2. The radiopharmaceutical automatic subpackaging and injection system according to claim 1, characterized in that: The raw liquid processing structure includes a raw liquid shielding tank and a tank inlet assembly; the raw liquid shielding tank is placed in the tank inlet assembly.

3. The automatic radiopharmaceutical sub-packaging and injection system according to claim 2, characterized in that: The raw liquid processing structure includes a pin assembly and a cover opening assembly, and the pin assembly and the cover opening assembly are assembled in the shell.

4. The automatic radiopharmaceutical sub-packaging and injection system according to claim 3, characterized in that: The fluid control structure includes a single three-way valve assembly, a liquid medicine pump, a double three-way valve assembly, an injection pump and a sub-packaging pipeline; the sub-packaging pipeline is respectively installed in the single three-way valve assembly, the liquid medicine pump, the double three-way valve assembly and the injection pump.

5. The radiopharmaceutical automatic subpackaging and injection system according to claim 4, characterized in that: The fluid control structure includes a dose calibrator, in which the dispensing pipeline is installed.

6. The radiopharmaceutical automatic subpackaging and injection system according to claim 1, characterized in that: The waste liquid management structure includes a waste liquid discharge port and a waste liquid bottle; the waste liquid discharge port is connected to the waste liquid bottle; and the waste liquid discharge port is connected to the subpackaging pipeline.

7. The automatic radiopharmaceutical sub-packaging and injection system according to claim 6, characterized in that: A waste liquid shielding chamber is provided on the side of the shell, and the waste liquid bottle is placed in the waste liquid shielding chamber.

8. The radiopharmaceutical automatic sub-packaging and injection system according to claim 1, characterized in that: The shell is provided with a sliding door; the control unit includes an operation screen, the operation screen is placed on the sliding door, and a lead shielding room is provided in the shell.

9. The radiopharmaceutical automatic subpackaging and injection system according to claim 1, characterized in that: The moving structure includes a roller, and the roller is assembled below the shell.

10. A method for operating the radiopharmaceutical automatic subpackaging and injection system according to any one of claims 1 to 9, characterized in that: include: The control structure starts and guides the raw liquid processing structure to make the raw liquid shielding tank enter the specified position and complete the pin insertion; The fluid control structure extracts saline and radioactive drugs, performs dose calibration and then performs precise injection; If waste liquid is generated, it will be automatically collected and stored by the waste liquid management structure; After all injections are completed, the lines are cleaned and the remaining drug is returned to the stock solution shielding tank and removed after safe decay.

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