Separation device for collagen peptide production and separation method thereof
By designing a separation device for collagen peptide production, using baffles and elastic supports to avoid repeated cake building, combined with automatic switching of the liquid inlet path, the problems of slow production speed and short filter membrane life in large-scale production are solved, and an efficient and continuous separation process is achieved.
Patent Information
- Application Number
- CN202510778557.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-11
- Publication Date
- 2025-09-12
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
In the existing technology, when producing collagen peptides on a large scale, repeated low-pressure cake building leads to slow production speed, high frequency of equipment start and stop, high energy consumption, and short service life of the filter membrane.
A separation device for collagen peptide production is used, including a separation tank, an extrusion plate, a filter element, a baffle and a monitor. After low-pressure cake formation, direct pressurization separation is performed. The baffle and elastic support design avoid repeated cake formation. The monitor detects flow changes to determine the timing of filter cake replacement, and automatically switches to protect the filter cake structure in combination with the liquid inlet path.
It speeds up the separation, prolongs the service life of the filter membrane, reduces energy consumption and mechanical loss, and improves the process consistency and efficiency of large-scale production.
Smart Images
Figure CN120620722A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the field of collagen peptide separation, and in particular to a separation device for collagen peptide production and a separation method thereof. Background Art
[0002] The production of collagen peptides has multi-dimensional applications in the manufacture of biopharmaceuticals. As bioactive macromolecules, they can be directly used as medicinal ingredients for wound repair, postoperative nutritional supplementation and auxiliary treatment of orthopedic diseases after being prepared by biomanufacturing technologies such as enzymatic hydrolysis and fermentation. Some high-purity peptides can also be used as active raw materials for polypeptide drugs.
[0003] In the production process of collagen peptides, solid-liquid separation is a key link after the enzymatic hydrolysis reaction. Its purpose is to separate the solid residues in the enzymatic hydrolyzate, such as incompletely hydrolyzed connective tissue, bone residue, fat particles, etc., from the liquid peptide solution, and provide a clear filtrate for subsequent purification and concentration. In the existing technical system, when the separation operation is started, first, by controlling the lower operating pressure, the solid particles in the enzymatic hydrolyzate are orderly deposited on the surface of the filter membrane, and gradually form a porous filter cake layer with interception effect. This dynamically constructed physical barrier can effectively change the movement trajectory of particles in the subsequent feed liquid, and significantly reduce the direct impact and wear of hard particles on the filter membrane surface, thereby protecting the integrity of the filter membrane structure while maintaining a stable filtrate flux. When the filter cake layer reaches the ideal density, the process design of gradually increasing the operating pressure not only ensures the filtration efficiency, but also extends the actual service life of the filter membrane through the layered interception principle.
[0004] However, when faced with large-scale production needs, the limitations of the traditional segmented pressure control process gradually become apparent. For enzymatic hydrolysate separation tasks with large daily processing volumes, due to the volume specifications of the separation equipment, the overall separation process often needs to be split into multiple batches for execution. The initial stage of each batch of filtration needs to go through the complete cycle from low-pressure cake building to pressure gradient increase again. This repetitive process not only leads to a significant increase in the time cost of a single filtration, but also causes the start-stop frequency and energy consumption of the filtration equipment to increase simultaneously. Summary of the Invention
[0005] The purpose of the present invention is to solve the shortcomings of the prior art of repeatedly undergoing low-pressure cake building, which affects the production speed, and to propose a separation device and a separation method for collagen peptide production.
[0006] To achieve the above objectives, the present invention adopts the following technical solution: a separation device for collagen peptide production, comprising a separation tank, wherein the separation tank is fixedly composed of a top tank and a bottom tank, the bottom of the bottom tank is fixedly connected to a discharge pipe, and further comprising:
[0007] An extrusion plate is provided inside the top tank, an electric push rod is fixed between the top surface of the extrusion plate and the top tank, and a mounting hole is provided in the middle of the extrusion plate;
[0008] A mounting tube is fixed in the mounting hole, and a liquid inlet assembly is provided inside the mounting tube, and the liquid inlet assembly is used to transport the enzymatic hydrolyzate to the bottom of the extrusion plate;
[0009] A filter element is provided inside the bottom tank, a support mesh plate is provided at the bottom of the filter element, and the support mesh plate is fixed to the inner wall of the bottom tank;
[0010] A shielding plate is provided below the mounting tube, and an elastic support member is provided between the shielding plate and the supporting mesh plate;
[0011] A monitor is installed in the discharge pipe and is used to detect flow changes in the discharge pipe. When the flow in the discharge pipe is less than a set value, it is determined that the filter cake is clogged.
[0012] Specifically, when performing the first batch of separation, the enzymatic hydrolyzate is first transported into the bottom of the extrusion plate by starting the liquid inlet component, and the enzymatic hydrolyzate passes through the filter element for separation. At the same time, by starting the electric push rod, the extrusion plate can be pushed down to perform low-pressure cake building. After the cake building is completed, the driving force is gradually increased to increase the pressure and speed up the separation. Among them, the filter element can be a filter membrane, filter cloth or filter element;
[0013] After the first batch of separation is completed, there is no need to remove the filter cake, and the second batch of enzymatic hydrolysate is directly introduced through the liquid inlet component. At this time, the baffle installed at the bottom of the liquid inlet component plays a diversion role, so that the newly introduced enzymatic hydrolysate, after impacting the baffle, spreads evenly from the center to the surrounding area in an umbrella shape, forming a laminar flow covering the surface of the original filter cake layer. This design avoids the concentrated impact of the traditional direct injection liquid on the filter cake layer, and in the separation process of the second batch of enzymatic hydrolysate, by ensuring the integrity of the filter cake layer, the low-pressure stage of repeated cake building is omitted, which is conducive to accelerating the separation speed;
[0014] It should be noted that after repeated use, the internal pores of the filter cake may be clogged with impurities and become dense, resulting in a reduction in the amount of collagen peptide solution after separation. By setting a monitor in the discharge pipe, the monitor can optionally use a flow sensor to monitor the flow change in the discharge pipe. When the flow in the discharge pipe decreases to the preset value, it indicates that the filter cake is clogged, thereby determining that the filter cake needs to be replaced after the separation of this batch of enzymatic hydrolysate is completed. A warning light or other warning device can be used to warn, avoiding the problem of reduced separation efficiency caused by not replacing the filter cake for a long time, and the top tank is inserted and fixed in the bottom tank. When removing the filter cake, the filter cake inside the top tank can be removed and the filter element replaced;
[0015] The filter cake layer formed in the first batch can be directly used as the pre-filtration medium for subsequent batches, eliminating the low-pressure stage of repeated cake building. The uniform liquid flow distribution significantly reduces the shear force on the filter cake layer, maintains its porous structure integrity, and is conducive to ensuring its filtration performance. In addition, by monitoring the flow rate of the discharged liquid and determining the filter cake replacement time, it is also beneficial to avoid the problem of reduced separation efficiency caused by long-term non-replacement of the filter cake. At the same time, it also reduces the frequency of filter cake replacement, avoids the mechanical wear of the filter membrane caused by frequent removal of the filter cake, effectively extends the service life of the filter membrane, shortens the single batch filtration time, and improves the process continuity during large-scale production.
[0016] Preferably, the elastic support member includes a fixed tube and a movable tube, the fixed tube is fixed on the supporting mesh plate, the bottom of the fixed tube passes through the supporting mesh plate and extends out, the top of the movable tube is fixed to the baffle plate, the movable tube is inserted into the inside of the fixed tube, and a first spring is arranged between the movable tube and the fixed tube.
[0017] Preferably, a guide cavity is provided inside the extrusion plate, and a plurality of inclined guide holes are provided on the bottom surface of the extrusion plate near the edge. A plurality of communicating holes are provided on the side wall of the mounting tube, and the communicating holes are connected with the inside of the guide cavity. The liquid inlet assembly includes two limiting rings, and the two limiting rings are fixed on the inner wall of the mounting tube. A sliding tube is provided between the two limiting rings, and a second spring is fixed between the sliding tube and the upper limiting ring. A liquid inlet valve is fixed inside the sliding tube, and a liquid inlet pipe is fixedly connected to the top of the top tank, and the liquid inlet valve is fixedly connected to the liquid inlet pipe through an elastic tube.
[0018] Specifically, in the initial state of the device, under the elastic force of the second spring, the rubber sliding tube is in close contact with the bottom limiting ring, and a seal is formed on the connecting hole on the mounting tube through the side wall. Since the present invention does not need to remove the filter cake after each filtration, the next batch of liquid can be immediately filled after the separation of the previous batch is completed. Therefore, when the extrusion plate is at the bottom, the liquid inlet valve can be opened, and the liquid is first discharged into the mounting tube. At this time, the bottom of the mounting tube is blocked by the baffle plate, and under the extrusion of the extrusion plate, the elastic support is in a compressed state. The elastic force of the first spring inside it is significantly greater than the second spring, and can overcome the hydraulic effect. Under the action of the hydraulic pressure, the drain valve and the sliding tube are pushed upward to expose the connecting hole. The liquid enters the guide cavity through the connecting hole and flows out from the guide hole obliquely arranged on the edge of the guide cavity. This inclined design allows the liquid to flow downward along the side wall of the top tank, avoiding direct impact on the surface of the filter cake and effectively protecting the filter cake structure.
[0019] However, although the smaller connecting holes can limit the amount of liquid entering and reduce the flow rate to a lower level when reaching the guide holes, further reducing the impact on the filter cake, it will also lead to limited liquid inlet speed and affect the overall separation efficiency. To this end, the present invention solves the above problem by automatically switching the liquid inlet path. The specific working method is as follows: when the solution gradually submerges the filter cake, the filter cake is fully protected by the liquid buffering effect, and there is no need to continue side wall drainage. At this time, as the extrusion plate rises, the elastic support member gradually extends, and the first spring force decreases accordingly, and eventually it cannot resist the hydraulic action. The baffle is pushed away from the bottom of the mounting tube, and the liquid inlet space is opened, and the liquid directly enters the top tank. This design protects the filter cake while automatically increasing the liquid inlet flow rate in the later stage of liquid inlet, taking into account the filter cake protection needs in the early stage of the filtration process and the high-efficiency separation requirements in the later stage.
[0020] Preferably, a water storage ring is fixed inside the diversion cavity, and a gap is provided between the top of the water storage ring and the top surface of the diversion cavity.
[0021] Specifically, when liquid is introduced, the extrusion plate is located at the position closest to the filter cake. At this time, the liquid is discharged directly from the guide hole to the inner wall of the top tank. The flow path flowing down along the inner wall is short, which may cause impact on the filter cake. In order to reduce the impact on the filter cake, the present invention arranges a water storage ring in the guide cavity. In the initial stage of liquid introduction, the liquid will first accumulate inside the water storage ring under the obstruction of the water storage ring, thereby providing time for the extrusion plate to rise, thereby extending the flow path of the liquid inside the top tank and reducing the impact on the edge of the filter cake.
[0022] Preferably, a buoyancy ring is slidably connected to the inner ring surface of the water storage ring, a floating plate is fixed on the top of the buoyancy ring, and a plurality of water-permeable grooves are opened on the top surface of the floating plate.
[0023] Preferably, a groove is provided on the top surface of the shielding plate, the bottom end of the mounting tube is inserted into the inside of the groove, an annular groove is provided on the side wall of the groove, an airbag ring is embedded in the annular groove, a plurality of guide grooves are provided inside the shielding plate, the airbag ring is fixedly connected to the guide groove, the bottom end of the guide groove is connected to the inside of the movable tube, and an air vent hole is provided at the bottom of the fixed tube.
[0024] Preferably, a sliding groove is provided on the inner wall of the fixed cylinder, and a slider is vertically slidably connected to the inside of the sliding groove. The slider is arranged below the movable tube, the first spring is fixed to the bottom of the slider, a third spring is fixed between the slider and the movable tube, and a telescopic tube is fixed between the slider and the movable tube.
[0025] Preferably, a first electromagnet is embedded and fixed inside the slider, a second electromagnet is embedded and fixed on the inner wall of the slide groove, a slot is opened inside the slider, a pulling block is slidably connected in the slot, a pulling rod is fixed on the top of the pulling block, and the top of the pulling rod passes through the pulling block and extends out to be fixed to the bottom of the movable tube.
[0026] Preferably, the annular groove is opened in an inclined state, and the annular groove is adapted to the airbag ring in an inclined manner.
[0027] A separation method for producing collagen peptides, the separation method comprising at least the following steps:
[0028] Step 1: Add the extracted collagenase hydrolysate into a separation tank in batches, and perform low-pressure cake making on the collagenase hydrolysate added in the first batch;
[0029] Step 2: Gradually increase the pressure to accelerate the separation of the collagen peptide solution. The collagen peptide solution passes through the filter inside the separation tank for solid-liquid separation to remove incompletely enzymatically hydrolyzed protein particles and impurities.
[0030] Step 3: After the separation of the previous batch is completed, the next batch of collagenase hydrolysate is introduced into the separation tank and directly pressurized;
[0031] Step 4: Obtain the outflow value of the collagen peptide solution after separation, and compare the outflow value with the preset value. When the outflow value reaches the preset value, the filter cake is replaced after the separation of the batch is completed.
[0032] Compared with the prior art, the present invention has the following beneficial effects:
[0033] 1. The present invention directly uses the filter cake layer formed in the first batch as the pre-filtration medium for subsequent batches, eliminating the low-pressure stage of repeated cake building, which is conducive to speeding up production. The uniform liquid flow distribution significantly reduces the shear force borne by the filter cake layer, maintains its porous structure integrity, and is conducive to ensuring its filtration performance. In addition, by monitoring the flow rate of the discharged liquid, the filter cake replacement time is determined, which is also conducive to avoiding the problem of reduced separation efficiency caused by long-term non-replacement of the filter cake. At the same time, it also reduces the frequency of filter cake replacement, avoids the mechanical wear of the filter membrane caused by frequent removal of the filter cake, effectively extends the service life of the filter membrane, shortens the single batch filtration time, and improves the process continuity during large-scale production.
[0034] 2. The present invention automatically switches the liquid inlet path, and in the early stage, the liquid is drained through the inner wall of the top tank to reduce the impact of the liquid on the filter cake. When the liquid level is higher than the filter cake to form protection, the liquid inlet flow rate is automatically increased in the later stage of liquid inlet, and the liquid inlet speed is improved, taking into account the filter cake protection requirements in the early stage of the filtration process and the high-efficiency separation requirements in the later stage.
[0035] 3. The present invention sets a water storage ring in the guide cavity. At the initial stage of liquid inflow, the liquid will first accumulate inside the water storage ring under the obstruction of the water storage ring, thereby providing time for the extrusion plate to rise, thereby extending the flow path of the liquid inside the top tank and reducing the impact on the edge of the filter cake. BRIEF DESCRIPTION OF THE DRAWINGS
[0036] Figure 1 It is a schematic diagram of the overall structure of the present invention.
[0037] Figure 2 It is a schematic diagram of the overall cross-sectional structure of the present invention.
[0038] Figure 3 For the present invention Figure 2 A in the figure is an enlarged structural diagram.
[0039] Figure 4 For the present invention Figure 2 The enlarged structural diagram at B in FIG.
[0040] Figure 5 For the present invention Figure 2 The enlarged structural diagram at C in FIG.
[0041] Figure 6 It is a schematic diagram of the cross-sectional structure of the shielding plate of the present invention.
[0042] Figure 7 It is a schematic diagram of the cross-sectional structure of the extruded plate of the present invention.
[0043] Figure 8 For the present invention Figure 7 The enlarged structural diagram at D in FIG.
[0044] Figure 9 Flow chart of the method of the present invention.
[0045] Figure: 1, separation tank; 2, top tank; 3, bottom tank; 4, discharge pipe; 5, extrusion plate; 6, electric push rod; 7, mounting hole; 8, mounting pipe; 9, filter element; 10, support mesh; 11, shielding plate; 12, monitor; 13, fixed cylinder; 14, movable pipe; 15, first spring; 16, diversion chamber; 17, diversion hole; 18, connecting hole; 19, limit ring; 20, slide pipe; 21, second spring; 22 , liquid inlet valve; 23, liquid inlet pipe; 24, elastic tube; 25, water storage ring; 26, buoyancy ring; 27, floating plate; 28, water-permeable groove; 29, groove; 30, ring groove; 31, airbag ring; 32, guide groove; 33, air vent; 34, slide; 35, slider; 36, third spring; 37, telescopic tube; 38, first electromagnet; 39, second electromagnet; 40, slot; 41, pull block; 42, pull rod. DETAILED DESCRIPTION
[0046] The following description is intended to disclose the present invention so that those skilled in the art can implement the present invention. The preferred embodiments described below are only examples, and those skilled in the art may conceive of other obvious variations.
[0047] like Figures 1 to 8 The separation device for collagen peptide production shown in the figure includes a separation tank 1, which is composed of a top tank 2 and a bottom tank 3 fixedly connected to the bottom of the bottom tank 3. A discharge pipe 4 is fixedly connected to the bottom of the bottom tank 3, and further includes:
[0048] The extrusion plate 5 is arranged inside the top tank 2. An electric push rod 6 is fixed between the top surface of the extrusion plate 5 and the top tank 2. A mounting hole 7 is opened in the middle of the extrusion plate 5.
[0049] The mounting tube 8 is fixed in the mounting hole 7. A liquid inlet assembly is provided inside the mounting tube 8 for delivering the enzymatic solution to the bottom of the extrusion plate 5.
[0050] The filter element 9 is arranged inside the bottom tank 3. A supporting mesh plate 10 is provided at the bottom of the filter element 9. The supporting mesh plate 10 is fixed to the inner wall of the bottom tank 3.
[0051] The shielding plate 11 is arranged below the mounting tube 8, and an elastic support member is provided between the shielding plate 11 and the supporting mesh plate 10;
[0052] The monitor 12 is installed in the discharge pipe 4 and is used to detect flow changes in the discharge pipe 4. When the flow in the discharge pipe 4 is less than a set value, it is determined that the filter cake is clogged.
[0053] Specifically, when performing the first batch of separation, the enzymatic hydrolyzate is first transported into the lower part of the extrusion plate 5 by starting the liquid inlet component, and the enzymatic hydrolyzate passes through the filter element 9 for separation. At the same time, by starting the electric push rod 6, the extrusion plate 5 can be pushed down to perform low-pressure cake building. After the cake building is completed, the driving force is gradually increased to increase the pressure and speed up the separation. Among them, the filter element 9 can be a filter membrane, filter cloth or filter element, etc.
[0054] After the first batch of separation is completed, there is no need to remove the filter cake, and the second batch of enzymatic hydrolysate is directly introduced through the liquid inlet component. At this time, the baffle 11 installed at the bottom of the liquid inlet component plays a diversion role, so that the newly introduced enzymatic hydrolysate, after impacting the baffle 11, spreads evenly from the center to the surrounding area in an umbrella shape, forming a laminar flow covering the surface of the original filter cake layer. This design avoids the concentrated impact of the traditional direct injection liquid on the filter cake layer, and in the separation process of the second batch of enzymatic hydrolysate, by ensuring the integrity of the filter cake layer, the low-pressure stage of repeated cake building is omitted, which is conducive to speeding up the separation speed;
[0055] It should be noted that after repeated use, the internal pores of the filter cake may be clogged with impurities and become dense, resulting in a decrease in the amount of collagen peptide solution after separation. By arranging a monitor 12 in the discharge pipe 4, the monitor 12 can use a flow sensor to monitor the flow change in the discharge pipe 4. When the flow in the discharge pipe 4 decreases to a preset value, it indicates that the filter cake is clogged, thereby determining that the filter cake needs to be replaced after the separation of this batch of enzymatic hydrolysate is completed. A warning light or other warning device can be used to warn, thereby avoiding the problem of reduced separation efficiency caused by not replacing the filter cake for a long time, and the top tank 2 is inserted and fixed in the bottom tank 3. When removing the filter cake, the filter cake inside the top tank 2 can be removed and the filter element 9 can be replaced;
[0056] In this embodiment, the filter cake layer formed in the first batch can be directly used as the pre-filtration medium for subsequent batches, eliminating the low-pressure stage of repeated cake building. The uniform liquid flow distribution significantly reduces the shear force on the filter cake layer, maintains its porous structure integrity, and is conducive to ensuring its filtration performance. In addition, by monitoring the flow rate of the discharged liquid and determining the filter cake replacement time, it is also beneficial to avoid the problem of reduced separation efficiency caused by long-term non-replacement of the filter cake. At the same time, it also reduces the frequency of filter cake replacement, avoids the mechanical wear of the filter membrane caused by frequent removal of the filter cake, effectively extends the service life of the filter membrane, shortens the single batch filtration time, and improves the process continuity during large-scale production.
[0057] As a further implementation scheme of the present invention, the elastic support member includes a fixed tube 13 and a movable tube 14. The fixed tube 13 is fixed on the supporting mesh plate 10. The bottom of the fixed tube 13 passes through the supporting mesh plate 10 and extends out. The top of the movable tube 14 is fixed to the baffle plate 11. The movable tube 14 is inserted into the inside of the fixed tube 13. A first spring 15 is arranged between the movable tube 14 and the fixed tube 13.
[0058] Specifically, the baffle plate 11 is supported by the movable tube 14, and the first spring 15 provides elastic supporting force, so that the baffle plate 11 can be in close contact with the bottom of the mounting tube 8 to block the bottom of the mounting tube 8. When the liquid inlet component infuses liquid to the bottom of the mounting plate, under the action of hydraulic pressure, it can overcome the elastic force of the first spring 15 and push the baffle plate 11 downward, thereby exposing the liquid inlet space and performing liquid inlet operations.
[0059] As a further implementation scheme of the present invention, a guide cavity 16 is opened inside the extrusion plate 5, and a plurality of inclined guide holes 17 are opened on the bottom surface of the extrusion plate 5 near the edge position. A plurality of connecting holes 18 are opened on the side wall of the mounting tube 8, and the connecting holes 18 are connected with the inside of the guide cavity 16. The liquid inlet component includes two limiting rings 19, and the two limiting rings 19 are fixed on the inner wall of the mounting tube 8. A sliding tube 20 is arranged between the two limiting rings 19, and a second spring 21 is fixed between the sliding tube 20 and the upper limiting ring 19. A liquid inlet valve 22 is fixed inside the sliding tube 20, and a liquid inlet pipe 23 is fixedly connected to the top of the top tank 2. The liquid inlet valve 22 is fixedly connected to the liquid inlet pipe 23 through an elastic tube 24.
[0060] Specifically, during the production of collagen peptides, the filter cake is formed by the loose accumulation of protein particles produced by enzymatic hydrolysis. It has a loose and porous structure and weak impact resistance. Although the baffle 11 can reduce the mainstream liquid flow velocity by diverting the flow and reduce direct impact, the liquid flow may produce some uneven splashing when it is discharged at the edge. These droplets or fluids with a certain amount of kinetic energy may still impact the surface of the filter cake. Due to the limited mechanical strength of the filter cake, such impact can easily cause surface particles to fall off or the structure to be damaged, thereby affecting the clarity of the filtrate and the filtration efficiency.
[0061] The present invention can solve the above problems. The specific working method is as follows: in the initial state of the device, under the elastic force of the second spring 21, the rubber sliding tube 20 is in close contact with the bottom limit ring 19, and the connecting hole 18 on the mounting tube 8 is sealed through the side wall. Since the present invention does not need to remove the filter cake after each filtration, the next batch of liquid can be immediately fed after the separation of the previous batch is completed. Therefore, when the extrusion plate 5 is at the bottom, the liquid inlet valve 22 can be opened, and the liquid is first discharged into the mounting tube 8. At this time, the bottom of the mounting tube 8 is blocked by the shielding plate. 11 is blocked, and under the extrusion of the extrusion plate 5, the elastic support is in a compressed state. The elastic force of the first spring 15 inside it is significantly greater than the second spring 21, and can overcome the hydraulic effect. Under the hydraulic effect, the drain valve and the slide pipe 20 are pushed upward, and the connecting hole 18 is exposed. The liquid enters the diversion cavity 16 through the connecting hole 18 and flows out from the diversion hole 17 inclined at the edge of the diversion cavity 16. This inclined design allows the liquid to flow downward along the side wall of the top tank 2, avoiding direct impact on the filter cake surface and effectively protecting the filter cake structure.
[0062] However, although the smaller connecting hole 18 can limit the amount of liquid entering and reduce the flow rate to a lower level when it reaches the guide hole 17, further reducing the impact on the filter cake, it will also lead to limited liquid inlet speed, affecting the overall separation efficiency. To this end, the present invention solves the above problem by automatically switching the liquid inlet path. The specific working method is as follows: when the solution gradually submerges the filter cake, the filter cake is fully protected by the liquid buffering effect, and there is no need to continue side wall drainage. At this time, as the extrusion plate 5 rises, the elastic support member gradually extends, and the elastic force of the first spring 15 decreases accordingly, and eventually it is unable to resist the hydraulic action. The baffle 11 is pushed away from the bottom of the mounting tube 8, and the liquid inlet space is opened, and the liquid directly enters the top tank 2. This design protects the filter cake while automatically increasing the liquid inlet flow rate in the later stage of liquid inlet, taking into account the filter cake protection needs in the early stage of the filtration process and the high-efficiency separation requirements in the later stage.
[0063] As a further embodiment of the present invention, a water storage ring 25 is fixed inside the diversion cavity 16 , and a gap is provided between the top of the water storage ring 25 and the top surface of the diversion cavity 16 .
[0064] Specifically, when liquid is introduced, the extrusion plate 5 is located closest to the filter cake. At this time, the liquid is discharged directly from the guide hole 17 to the inner wall of the top tank 2. The flow path flowing down along the inner wall is short, which may cause impact on the filter cake. In order to reduce the impact on the filter cake, the present invention provides a water storage ring 25 in the guide cavity 16. In the early stage of liquid introduction, the liquid will first accumulate inside the water storage ring 25 under the obstruction of the water storage ring 25, thereby providing time for the extrusion plate 5 to rise, thereby extending the flow path of the liquid inside the top tank 2 and reducing the impact on the edge of the filter cake.
[0065] When the liquid fills the water storage ring 25, it will overflow from the top of the water storage ring 25. The overflow effect can ensure that the liquid can evenly enter each guide hole 17 and ensure that the solution can evenly flow downward along the inner wall of the top tank 2, which is beneficial to reduce the uneven impact on the edge of the filter cake.
[0066] It should be noted that the extrusion plate 5 can be made by combining two upper and lower plates, so as to facilitate disassembly and cleaning. This is the existing technology and will not be elaborated on here.
[0067] As a further embodiment of the present invention, a buoyancy ring 26 is slidably connected to the inner ring surface of the water storage ring 25 , a floating plate 27 is fixed on the top of the buoyancy ring 26 , and a plurality of water-permeable grooves 28 are opened on the top surface of the floating plate 27 .
[0068] Specifically, if the liquid inlet flow rate fluctuates greatly, when the liquid inlet flow rate is large, it may cause the discharge volume at the guide hole 17 position to be lower than the water inlet volume at the liquid inlet position. The excess water may be accumulated because it cannot flow out, resulting in increased water pressure and faster flow rate during discharge, which in turn damages the fragile filter cake. In order to solve the above problem, the present invention provides a buoyancy ring 26 in the water storage ring 25, and fixes a float plate 27 on the top of the buoyancy ring 26. The liquid can overflow to the guide hole 17 from the water permeable groove 28 on the surface of the float plate 27. As the liquid increases, the float plate 27 uses a lightweight material. Under the action of buoyancy, the float plate 27 will move upward. As the liquid level rises, the liquid can only flow out from the water permeable groove 28. Since the notch of the water permeable groove 28 is small, the problem of excessive hydraulic pressure at the guide hole 17 position is solved, which is beneficial to reduce the fluctuation of the liquid inlet flow rate and the adverse effects on the filter cake, and is beneficial to further protect the filter cake.
[0069] As a further implementation scheme of the present invention, a groove 29 is provided on the top surface of the baffle plate 11, the bottom end of the mounting tube 8 is inserted into the inside of the groove 29, an annular groove 30 is provided on the side wall of the groove 29, an airbag ring 31 is embedded in the annular groove 30, a plurality of guide grooves 32 are provided inside the baffle plate 11, the airbag ring 31 is fixedly connected to the guide groove 32, the bottom end of the guide groove 32 is connected to the inside of the movable tube 14, and an air vent hole 33 is provided at the bottom of the fixed tube 13.
[0070] Specifically, during the downward pressing process of the extrusion plate 5, the shielding plate 11 can block the bottom of the mounting tube 8, reducing the adverse effects of the hydraulic pressure on the liquid inlet valve 22. In order to further reduce the hydraulic pressure, the present invention has made further improvements to the shielding plate 11 by providing a groove 29 on the top surface of the shielding plate 11, so that the mounting tube 8 is inserted into the groove 29, and an airbag ring 31 is provided between the side wall of the groove 29 and the mounting tube 8. When the elastic support member is shortened, the gas in the fixing tube 13 is squeezed into the airbag ring 31, causing the airbag ring 31 to inflate, thereby improving the sealing between the shielding plate 11 and the mounting tube 8, isolating the liquid inlet valve 22 from the pressurized solution, and facilitating further protection of the liquid inlet valve 22.
[0071] It should be noted that the internal space of the fixed cylinder 13 is large, and the amount of gas actually required inside the airbag ring 31 is relatively small. This situation will make it difficult for the gas in the fixed cylinder 13 to completely rush into the internal space of the airbag ring 31, thereby adversely affecting the descending function of the movable tube 14. The present invention provides an air vent 33 at the bottom of the fixed cylinder 13. The air vent 33 is small, so that after the airbag ring 31 is filled, the excess gas in the fixed cylinder 13 can be discharged through the air vent 33, thereby avoiding adverse effects on the descent of the movable tube 14.
[0072] As a further embodiment of the present invention, a sliding groove 34 is opened on the inner wall of the fixed cylinder 13, and a slider 35 is vertically slidably connected inside the sliding groove 34. The slider 35 is arranged below the movable tube 14, and the first spring 15 is fixed to the bottom of the slider 35. A third spring 36 is fixed between the slider 35 and the movable tube 14, and a telescopic tube 37 is fixed between the slider 35 and the movable tube 14.
[0073] Specifically, in the initial stage of liquid inflow, if it is desired to allow liquid to enter from the communicating hole 18 and be discharged from the guide hole 17, a strong seal must be provided between the shielding plate 11 and the mounting tube 8 to maintain the compressed state of the second spring 21. However, as can be seen from the above embodiment, during the liquid inflow process, the extrusion plate 5 tends to rise, and the elastic support member will gradually extend. The extension of the elastic support member will absorb the gas in the airbag ring 31, causing the airbag ring 31 to shrink and reduce the sealing performance. In order to maintain the effective sealing of the airbag ring 31 in both the initial stage of liquid inflow and the pressurization stage, the present invention further improves the interior of the elastic support member. The specific improvement is as follows: by providing a telescopic tube 37 structure at the bottom of the movable tube 14, since the elastic force of the first spring 15 is significantly greater than the elastic force of the third spring 36, when the movable tube 14 begins to descend, the third spring 36 will be compressed first, causing the telescopic tube 37 to shorten. At this time, the gas inside the telescopic tube 37 will be squeezed into the interior of the airbag ring 31, thereby improving the sealing performance between the shielding plate 11 and the mounting tube 8 in the pressurization stage.
[0074] During the subsequent descent of the movable tube 14, the telescopic tube 37 is gradually compressed to its limit volume. When this limit volume is reached, the telescopic tube 37 stops shrinking and transmits the force it receives to the slider 35. This force transfer pushes the slider 35 to compress the first spring 15, thereby achieving the function of continuously descending the movable tube 14. During the entire descent of the slider 35, the gas inside the fixed tube 13 can be smoothly discharged from the bleed hole 33.
[0075] During the upward movement of the movable tube 14, the elastic force of the first spring 15 is greater than the elastic force of the third spring 36, so that the third spring 36 is always in a compressed state, and the airbag ring 31 remains in an expanded state, which is conducive to maintaining the sealing performance between the baffle plate 11 and the mounting tube 8 in the initial stage of liquid inflow;
[0076] When the slider 35 rises to the top position of the chute 34, the slider 35 stops rising under the obstruction of the chute 34. Thereafter, as the extrusion plate 5 continues to rise, the telescopic tube 37 will gradually extend, absorbing the gas inside the airbag ring 31, thereby ensuring that the sealing performance between the baffle plate 11 and the mounting tube 8 can be reduced in the later stage of liquid filling, making it easier to hydraulically open the baffle plate 11, so that the solution can be directly discharged from the bottom of the mounting tube 8 into the interior of the top tank 2, ensuring the liquid filling speed;
[0077] This embodiment uses the setting of the telescopic tube 37 to ensure that the amount of gas squeezed into the airbag ring 31 remains stable during the initial liquid filling stage and the pressurization stage, and always maintains the airbag ring 31 in a stable expansion state, ensuring the continuity and reliability of the sealing effect.
[0078] As a further embodiment of the present invention, a first electromagnet 38 is embedded and fixed inside the slider 35, and a second electromagnet 39 is embedded and fixed on the inner wall of the slide groove 34. A slot 40 is opened inside the slider 35, and a pulling block 41 is slidably connected in the slot 40. A pull rod 42 is fixed to the top of the pulling block 41. The top of the pull rod 42 passes through the pulling block 41 and extends out to be fixed to the bottom of the movable tube 14;
[0079] Specifically, in the above embodiment, the sealing performance between the baffle 11 and the mounting tube 8 can only be reduced when the slider 35 moves to the top of the slide groove 34. In order to further improve the liquid inlet speed, the present invention provides a first electromagnet 38 inside the slider 35 and a second electromagnet 39 inside the slide groove 34. When descending, the first electromagnet 38 and the second electromagnet 39 are in a power-off state, thereby not affecting the descent of the slider 35. During the liquid inlet process, the slider 35 is in an ascending state. At this time, the first electromagnet 38 and the second electromagnet 39 are in a power-on state. When the slider 35 moves to the position of the second electromagnet 39, When the first electromagnet 38 and the second electromagnet 39 are in the position, the slider 35 is restricted from moving upwards under the adsorption effect of the first electromagnet 38 and the second electromagnet 39, so that the movable tube 14 moves upwards alone and pulls the top of the telescopic tube 37, so that the telescopic tube 37 extends and inhales air, causing the airbag ring 31 to contract, reducing the sealing between the baffle 11 and the mounting tube 8, thereby facilitating the hydraulic pressure in the mounting tube 8 to push open the baffle 11, so that the solution can be directly discharged from the bottom of the mounting tube 8 into the interior of the top tank 2, so that after the solution does not form a filter cake protection, the liquid can be immediately introduced from the bottom of the mounting tube 8, further improving the liquid inlet speed, thereby accelerating the separation speed of the collagen peptides;
[0080] Furthermore, during the extension of the telescopic tube 37, under the pull of the pull rod 42, the pulling block 41 slides upward in the slot 40, and a pressure switch is installed at the top of the slot 40. When the pulling block 41 triggers the pressure switch, the adsorption state of the first electromagnet 38 and the second electromagnet 39 can be cancelled, so that the movable tube 14 can continue to rise.
[0081] As a further embodiment of the present invention, the annular groove 30 is opened in an inclined state, and the annular groove 30 is adapted to the airbag ring 31 in an inclined manner.
[0082] Specifically, as the movable tube 14 continues to rise, under the push of the first spring 15, the slider 35 pushes the telescopic tube 37 upward, and under the action of hydraulic pressure, the movable tube 14 is pushed downward from the top, so that the movable tube 14 squeezes the telescopic tube 37 downward, and the telescopic tube 37 continues to shorten, so that the airbag is re-inflated. Under the action of expansion, when the liquid inlet pressure fluctuates greatly, when the liquid inlet pressure becomes smaller, after the mounting tube 8 is inserted into the groove 29, by tilting the airbag ring 31, its structure will always keep the liquid inlet gap exposed, thereby ensuring that the liquid can pass through the gap smoothly into the top tank 2.
[0083] like Figure 9 A separation method for producing collagen peptides is shown, which comprises at least the following steps:
[0084] Step 1: Add the extracted collagenase hydrolysate into the separation tank 1 in batches, and perform low-pressure cake making on the collagenase hydrolysate added in the first batch;
[0085] Step 2: gradually increase the pressure to speed up the separation of the collagen peptide solution. The collagen peptide solution passes through the filter element 9 inside the separation tank 1 for solid-liquid separation to remove incompletely enzymatically hydrolyzed protein particles and impurities.
[0086] Step 3: After the separation of the previous batch is completed, the next batch of collagenase hydrolysate is introduced into the separation tank 1 and directly pressurized;
[0087] Step 4: Obtain the outflow value of the collagen peptide solution after separation, and compare the outflow value with the preset value. When the outflow value reaches the preset value, the filter cake is replaced after the separation of the batch is completed.
[0088] The basic principles, main features, and advantages of the present invention are shown and described above. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions only describe the principles of the present invention. Various changes and improvements are possible without departing from the spirit and scope of the present invention, and such changes and improvements fall within the scope of the invention as claimed.
Claims
1. A separation device for producing collagen peptides, comprising a separation tank (1), wherein the separation tank (1) is fixedly composed of a top tank (2) and a bottom tank (3), and the bottom of the bottom tank (3) is fixedly connected to a discharge pipe (4), characterized in that: Also includes: An extrusion plate (5), the extrusion plate (5) being arranged inside the top tank (2), an electric push rod (6) being fixed between the top surface of the extrusion plate (5) and the top tank (2), and a mounting hole (7) being provided in the middle of the extrusion plate (5); A mounting tube (8), wherein the mounting tube (8) is fixed in the mounting hole (7), and a liquid inlet assembly is provided inside the mounting tube (8), and the liquid inlet assembly is used to transport the enzymatic hydrolyzate to the bottom of the extrusion plate (5); A filter element (9), the filter element (9) being arranged inside the bottom tank (3), a supporting mesh plate (10) being arranged at the bottom of the filter element (9), and the supporting mesh plate (10) being fixed on the inner wall of the bottom tank (3); A shielding plate (11), the shielding plate (11) is arranged below the mounting tube (8), and an elastic support member is provided between the shielding plate (11) and the supporting mesh plate (10); A monitor (12) is installed in the discharge pipe (4) and is used to detect flow changes in the discharge pipe (4). When the flow in the discharge pipe (4) is less than a set value, it is determined that the filter cake is blocked.
2. A separation device for collagen peptide production according to claim 1, characterized in that: The elastic support member comprises a fixed tube (13) and a movable tube (14); the fixed tube (13) is fixed on the supporting mesh plate (10); the bottom of the fixed tube (13) passes through the supporting mesh plate (10) and extends out; the top of the movable tube (14) is fixed to the shielding plate (11); the movable tube (14) is inserted into the interior of the fixed tube (13); and a first spring (15) is provided between the movable tube (14) and the fixed tube (13).
3. The separation device for collagen peptide production according to claim 1, characterized in that: A guide cavity (16) is provided inside the extrusion plate (5), and a plurality of inclined guide holes (17) are provided on the bottom surface of the extrusion plate (5) near the edge. A plurality of communicating holes (18) are provided on the side wall of the mounting tube (8), and the communicating holes (18) are communicated with the inside of the guide cavity (16). The liquid inlet assembly includes two limiting rings (19), and the two limiting rings (19) are fixed on the inner wall of the mounting tube (8). A sliding tube (20) is provided between the two limiting rings (19), and a second spring (21) is fixed between the sliding tube (20) and the upper limiting ring (19). A liquid inlet valve (22) is fixed inside the sliding tube (20), and a liquid inlet pipe (23) is fixedly connected to the top of the top tank (2). The liquid inlet valve (22) is fixedly communicated with the liquid inlet pipe (23) through an elastic tube (24).
4. A separation device for collagen peptide production according to claim 3, characterized in that: A water storage ring (25) is fixed inside the diversion cavity (16), and a gap is provided between the top of the water storage ring (25) and the top surface of the diversion cavity (16).
5. A separation device for collagen peptide production according to claim 4, characterized in that: A buoyancy ring (26) is slidably connected to the inner ring surface of the water storage ring (25), a floating plate (27) is fixed on the top of the buoyancy ring (26), and a plurality of water-permeable grooves (28) are provided on the top surface of the floating plate (27).
6. A separation device for collagen peptide production according to claim 2, characterized in that: A groove (29) is provided on the top surface of the shielding plate (11), the bottom end of the mounting tube (8) is inserted into the groove (29), a ring groove (30) is provided on the side wall of the groove (29), an airbag ring (31) is embedded in the ring groove (30), a plurality of guide grooves (32) are provided inside the shielding plate (11), the airbag ring (31) is fixedly connected to the guide groove (32), the bottom end of the guide groove (32) is connected to the inside of the movable tube (14), and an air leakage hole (33) is provided at the bottom of the fixed tube (13).
7. A separation device for collagen peptide production according to claim 6, characterized in that: A sliding groove (34) is provided on the inner wall of the fixed cylinder (13), and a slider (35) is vertically slidably connected inside the sliding groove (34). The slider (35) is arranged below the movable tube (14), the first spring (15) is fixed to the bottom of the slider (35), a third spring (36) is fixed between the slider (35) and the movable tube (14), and a telescopic tube (37) is fixed between the slider (35) and the movable tube (14).
8. The separation device for collagen peptide production according to claim 7, characterized in that: A first electromagnet (38) is embedded and fixed inside the slider (35), a second electromagnet (39) is embedded and fixed on the inner wall of the slide groove (34), a slot (40) is provided inside the slider (35), a pulling block (41) is slidably connected in the slot (40), a pulling rod (42) is fixed on the top of the pulling block (41), and the top of the pulling rod (42) passes through the pulling block (41) and extends out to be fixed to the bottom of the movable tube (14).
9. The separation device for collagen peptide production according to claim 8, characterized in that: The annular groove (30) is opened in an inclined state, and the annular groove (30) is adapted to be inclined with the airbag ring (31).
10. A separation method for collagen peptide production, applicable to the separation device for collagen peptide production according to any one of claims 1 to 9, characterized in that: The separation method comprises at least the following steps: Step 1: Add the extracted collagenase hydrolysate into a separation tank (1) in batches, and perform low-pressure cake making on the collagenase hydrolysate added in the first batch; Step 2: gradually increase the pressure to accelerate the separation speed of the collagen peptide solution, and the collagen peptide solution passes through the filter element (9) inside the separation tank (1) to perform solid-liquid separation and remove incompletely enzymatically hydrolyzed protein particles and impurities; Step 3: After the separation of the previous batch is completed, the next batch of collagenase hydrolysate is introduced into the separation tank (1) and directly pressurized; Step 4: Obtain the outflow value of the collagen peptide solution after separation, and compare the outflow value with the preset value. When the outflow value reaches the preset value, the filter cake is replaced after the separation of the batch is completed.