Intelligent biological sample measuring and sampling device
Through the design of an intelligent biological sample measurement and sampling device, combined with components such as hydraulic cylinders, robotic arms and three-dimensional scanning cameras, the automated measurement and sampling of biological samples are achieved, solving the problems of cumbersome operation and low efficiency in existing technologies, and improving the convenience and standardization of sampling.
Patent Information
- Application Number
- CN202511074879.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-08-01
- Publication Date
- 2025-09-16
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing biological sample measurement devices are cumbersome to operate, cannot automatically collect and process samples, and require manual collection afterwards, resulting in low efficiency.
An intelligent biological sample measurement and sampling device is designed, which includes a sampling mechanism, an auxiliary mechanism and a cleaning mechanism. It uses components such as a hydraulic cylinder, a robotic arm, and a three-dimensional scanning camera to realize the automated biological sample measurement and sampling process, and is equipped with a cleaning system for self-cleaning.
It realizes the automated measurement and sampling of biological samples, improves the convenience of measurement and the efficiency of sampling, reduces the tediousness and errors of manual operation, and ensures the standardization and safety of sampling.
Smart Images

Figure CN120651562A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of laboratory sampling, and in particular to an intelligent biological sample measurement and sampling device. Background Art
[0002] An animal laboratory, also known as an experimental animal room, is a building suitable for raising and breeding experimental animals. This type of building should have specific environmental requirements and experimental methods to ensure the quality of the animals and the accuracy and reliability of experimental research.
[0003] Biological samples usually refer to body fluids (such as urine, blood, saliva, bile, gastric juice, lymph and other secretions of organisms), hair, muscles and some tissues and organs (such as thymus, pancreas, liver, lungs, brain, stomach, kidneys, etc.) of animals (including humans) and various microorganisms; biological samples need to be stored at low temperatures, and when collecting biological samples, the size of the biological samples needs to be measured and the samples need to be processed.
[0004] The prior art publication number CN219454892U discloses a biological sample collection table, comprising: a collection table, the top of which is respectively provided with an outer box and an inner box, the outer box cover being placed on the outside of the inner box; a measuring part, which is located in the inner box, the measuring part comprising a first scale, a second scale and a third scale, the first scale and the third scale are both parallel to the surface of the collection table and the first scale and the third scale are perpendicular to each other, and the second scale is perpendicular to the surface of the collection table; and a driving part, used to drive the first scale, the second scale and the third scale to move in the inner box respectively.
[0005] When in use, it uses multiple scales to measure biological samples, which is cumbersome to operate. In addition, it can only perform measurements but not sample collection and processing. Manual sample collection and processing is required later. Therefore, it is necessary to design an intelligent biological sample measurement and sampling device to solve the above problems.
[0006] The information disclosed in this background technology section is only intended to enhance understanding of the overall background of the invention and should not be regarded as an admission or any form of suggestion that the information constitutes the prior art already known to a person skilled in the art. Summary of the Invention
[0007] The purpose of the present invention is to provide an intelligent biological sample measurement and sampling device to solve the above problems.
[0008] The above technical objectives of the present invention are achieved through the following technical solutions: An intelligent biological sample measurement and sampling device, comprising: A material collection platform, wherein the material collection platform is provided with a material collection mechanism, an auxiliary mechanism 1, an auxiliary mechanism 2 and a cleaning mechanism; The material collection mechanism includes a frame, a three-dimensional scanning camera, a mechanical arm, a vertical arm, a power motor, a power shaft, a slide plate, a clamping arm, a rope body, a side plate and a material collection head; The frame and the three-dimensional scanning camera are both fixedly mounted on the material collection table, the robotic arm is fixedly mounted on the top inner wall of the frame, the vertical arm is fixedly mounted on the bottom of the robotic arm, the power motor is fixedly mounted on a vertical arm, the output end of the power motor is fixedly connected to the power shaft, a two-way thread is provided on the outer side of the power shaft, the two-way thread is threadedly connected to the slide, the clamping arm is vertically slidably sleeved on the outer side of the slide, a flat plate is fixedly provided on the side of the slide, the rope body is fixedly mounted between the flat plate and the side plate, the side plate is fixedly mounted on the side of the clamping arm, and the material collection head is fixedly mounted on the bottom of the robotic arm.
[0009] The present invention is further configured as follows: the auxiliary mechanism includes a hydraulic cylinder, a rotating shaft, a placing table, blades, a positioning groove, a collection box and an anti-slip pad, the bottom of the hydraulic cylinder is fixedly mounted on the material collection table, the rotating shaft is rotatably mounted on the hydraulic rod of the hydraulic cylinder through a damping washer, the placing table is fixedly mounted on the top of the rotating shaft, the blades are fixedly mounted on the outside of the rotating shaft, the positioning groove is opened at the top of the placing table, the bottom of the collection box is fixedly connected to the anti-slip pad, and the collection box is placed on the top of the collection box through the anti-slip pad.
[0010] The present invention is further configured as follows: the auxiliary mechanism 2 includes a tube body 1, a plate body 1, a plate body 2, an elastic airbag, a cylinder body, an electromagnetic valve 1, a one-way valve 2, a horizontal plate, a rod body, a piston, a tube body 2 and a one-way valve 1, the tube body 1 is fixedly installed on the material collecting head and the robotic arm, the plate body 1 and the plate body 2 are both fixedly installed on the side wall of the frame, the elastic airbag is fixedly installed between the plate body 1 and the plate body 2, the cylinder body and the tube body 1 are both fixedly connected to the elastic airbag, the electromagnetic valve 1 is installed on the tube body 1, the one-way valve 2 is installed on the cylinder body, the horizontal plate is fixedly installed on the side wall of the frame, the rod body is vertically slidably installed on the horizontal plate, the top of the rod body is fixedly connected to the piston, the piston sliding seal is installed inside the cylinder body, the tube body 2 is fixedly installed on the piston, and the one-way valve 1 is fixedly installed on the tube body 2.
[0011] By adopting the above technical solution, it is convenient to remove the sampled tissue block.
[0012] The present invention is further configured as follows: the auxiliary mechanism two also includes a tube body three, a solenoid valve two, a support plate, a branch pipe and a solenoid valve three, the tube body three is fixedly mounted on the tube body one, the solenoid valve two is mounted on the tube body three, the side of the support plate is fixedly connected to a clamping arm, the top of the support plate is in contact with the rod body, the branch pipe is fixedly mounted on the tube body three, the solenoid valve three is mounted on the branch pipe, and a solenoid valve four is installed at the bottom of the tube body three.
[0013] The present invention is further configured as follows: the cleaning mechanism includes a cleaning box, a positioning block, a main pipe, an auxiliary pipe, a connecting pipe 1, a connecting pipe 2, a nozzle 1, a nozzle 2, a cleaning brush 1, a cleaning brush 2, a rotating part, a water storage tank, a pump body, a water outlet pipe and a water filling pipe; the positioning block is fixedly mounted on the bottom of the cleaning box; the main pipe is fixedly mounted on the cleaning box; the auxiliary pipe, connecting pipe 1 and connecting pipe 2 are all fixedly connected to the main pipe; the nozzle 1 and the cleaning brush 1 are both fixedly mounted on the connecting pipe 1; the nozzle 2 and the cleaning brush 2 are both fixedly mounted on the connecting pipe 2; the rotating part is rotatably sleeved on the outside of the material collection head through a damping washer; the water storage tank is opened at the top of the rotating part; the pump body is fixedly mounted on the bottom of the rotating part; the bottom of the pump body is fixedly connected to the water outlet pipe; and the water filling pipe is fixedly mounted on the material collection table.
[0014] By adopting the above technical solution, the sampling head can be easily cleaned and used next time.
[0015] The present invention is further configured as follows: a display screen is installed on the top inner wall of the material collection table, and a cleaning pool is installed on the bottom inner wall of the material collection table.
[0016] By adopting the above technical solution, the setting of the cleaning pool makes it convenient for staff to carry out cleaning work.
[0017] The present invention is further configured as follows: an adapting circular hole is provided at the bottom of the frame.
[0018] The present invention is further configured as follows: a moving block is fixedly provided on the rear side of the skateboard, a moving groove is provided on the inner wall of the rear side of the frame, and the moving block is laterally slidably installed in the moving groove.
[0019] The present invention is further configured such that the auxiliary pipe, the first connecting pipe and the second connecting pipe are all connected to the interior of the main pipe.
[0020] By adopting the above technical solution, the flow of the cleaning liquid is facilitated.
[0021] The present invention is further configured as follows: the first nozzle is connected to the interior of the first connecting pipe, and the second nozzle is connected to the interior of the second connecting pipe.
[0022] The beneficial effects of the present invention are: The present invention places the experimental animal specimen on the top of the placing table through the provision of a sampling mechanism and an auxiliary mechanism. The hydraulic cylinder is activated, so that the placing table drives the experimental animal specimen to move upward. The experimental animal specimen is subjected to three-dimensional scanning and imaging processing by a three-dimensional scanning camera. The hydraulic cylinder is continuously activated until the top of the placing table contacts the clamping arm. The experimental animal specimen is clamped and fixed by the two clamping arms. Then, the hydraulic cylinder is continuously activated, so that the placing table pushes the clamping arm, and the clamping arm drives the experimental animal specimen to move upward until the sampling head samples the experimental animal specimen, thereby facilitating automatic sampling and processing. The present invention provides a material taking mechanism and an auxiliary mechanism 2, and can inflate the elastic airbag during the process of the placement table moving up. During the three-dimensional scanning and imaging process, the electromagnetic valve 2 and the electromagnetic valve 4 are activated, so that the air in the elastic airbag is discharged from the tube body 3. The air discharged from the tube body 3 blows the blades, causing the blades to rotate, and the blades drive the rotating shaft to rotate, and the rotating shaft drives the placement table to rotate, and the placement table drives the experimental animal specimen to rotate. Through the cooperation of the three-dimensional scanning camera, the experimental animal specimen can be well three-dimensionally imaged. After the three-dimensional imaging process, the size of the experimental animal specimen can be automatically determined by comparing with the data in the database, which is convenient for measuring the size of the experimental animal specimen and is relatively convenient. The present invention provides a sampling mechanism and an auxiliary mechanism 2, activates the electromagnetic valve 1, and the air in the elastic airbag enters the sampling head through the tube 1, applying a certain air pressure to the interior of the sampling head, so that the tissue blocks sampled in the sampling head can be discharged from the interior of the sampling head and discharged into the collection box, and immersed in the formaldehyde solution in the collection box, so that the tissue blocks can be collected easily; The present invention starts the hydraulic cylinder by setting auxiliary mechanism 1, auxiliary mechanism 2 and cleaning mechanism, so that the placement table drives the cleaning box to move upward until the auxiliary pipe is inserted into the water outlet pipe. At this time, the branch pipe is aligned with the blade, and the pump body and solenoid valve 3 are opened to rotate the blade, and then the cleaning box can be rotated. After the pump body is turned on, the cleaning liquid can be sprayed out from nozzle 1 and nozzle 2. The connecting pipe 1 drives the nozzle 1 and the cleaning brush 1 to rotate, so that the outside of the material collection head can be cleaned. The connecting pipe 2 drives the nozzle 2 and the cleaning brush 2 to rotate, so that the inside of the material collection head can be cleaned, which makes it convenient to clean the material collection head after the material collection is completed, and facilitates the subsequent material collection processing. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.
[0024] Figure 1 It is a schematic diagram of the three-dimensional structure of an intelligent biological sample measurement and sampling device proposed by the present invention.
[0025] Figure 2 The diagram is a structural diagram of the sampling mechanism of an intelligent biological sample measurement and sampling device proposed by the present invention.
[0026] Figure 3 The diagram is a structural diagram of the sampling mechanism of an intelligent biological sample measurement and sampling device proposed by the present invention.
[0027] Figure 4 yes Figure 3 Schematic diagram of the structure of part A in .
[0028] Figure 5 The figure is a schematic cross-sectional structural diagram of a sampling mechanism in an intelligent biological sample measurement and sampling device proposed by the present invention.
[0029] Figure 6 yes Figure 5 Schematic diagram of the structure of part B.
[0030] Figure 7 yes Figure 5 Schematic diagram of the structure of part C in .
[0031] Figure 8 yes Figure 5 Schematic diagram of the structure of part D in .
[0032] Figure 9 yes Figure 5 Schematic diagram of the structure of part E in .
[0033] Figure 10 It is a structural schematic diagram of a part of the auxiliary mechanism in an intelligent biological sample measurement and sampling device proposed by the present invention.
[0034] Figure 11 yes Figure 10 Schematic diagram of the structure of part F in .
[0035] Figure 12 This is a structural diagram of an auxiliary mechanism in an intelligent biological sample measurement and sampling device proposed by the present invention after a collection box is placed.
[0036] Figure 13 The figure is a structural diagram of two parts of the auxiliary mechanism in an intelligent biological sample measurement and sampling device proposed by the present invention.
[0037] Figure 14 The figure is a schematic structural diagram of the cleaning mechanism in an intelligent biological sample measurement and sampling device proposed by the present invention.
[0038] Figure 15 The figure is a schematic cross-sectional view of the cleaning mechanism of an intelligent biological sample measuring and sampling device proposed by the present invention.
[0039] In the figure, 1, the material collection platform; 2. Material collection mechanism; 201. Frame; 202. 3D scanning camera; 203. Robotic arm; 204. Vertical arm; 205. Power motor; 206. Power shaft; 207. Slide plate; 208. Clamping arm; 209. Rope; 210. Side plate; 211. Material collection head; 3. Auxiliary mechanism 1; 301. Hydraulic cylinder; 302. Rotating shaft; 303. Placement table; 304. Blade; 305. Positioning groove; 306. Collection box; 307. Anti-slip pad; 4. Auxiliary mechanism 2; 401. Tube body 1; 402. Plate body 1; 403. Plate body 2; 404. Elastic airbag; 405. Cylinder; 406. Solenoid valve 1; 407. Check valve 2; 408. Horizontal plate; 409. Rod; 410. Piston; 411. Tube body 2; 412. Check valve 1; 413. Tube body 3; 414. Solenoid valve 2; 415. Support plate; 416. Branch pipe; 417. Solenoid valve 3; 5. Cleaning mechanism; 501. Cleaning box; 502. Positioning block; 503. Main pipe; 504. Auxiliary pipe; 505. Connecting pipe 1; 506. Connecting pipe 2; 507. Nozzle 1; 508. Nozzle 2; 509. Cleaning brush 1; 510. Cleaning brush 2; 511. Rotating member; 512. Water storage tank; 513. Pump body; 514. Water outlet pipe; 515. Water supply pipe; 6. Display screen; 7. Cleaning pool. DETAILED DESCRIPTION
[0040] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be internal communication between two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood based on specific circumstances.
[0041] The technical solutions of the present invention will be described clearly and completely below with reference to specific embodiments. Obviously, the embodiments described are only some of the embodiments of the present invention, not all of them. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without inventive effort are also within the scope of protection of the present invention.
[0042] See also Figures 1-15 The present invention provides an intelligent biological sample measurement and sampling device, comprising: The material collection platform 1 is provided with a material collection mechanism 2, an auxiliary mechanism 1 3, an auxiliary mechanism 2 4 and a cleaning mechanism 5; Reference Figure 5 and Figure 6 The material collection mechanism 2 includes a frame 201, a three-dimensional scanning camera 202, a mechanical arm 203, a vertical arm 204, a power motor 205, a power shaft 206, a slide 207, a clamping arm 208, a rope body 209, a side plate 210 and a material collection head 211; The frame 201 and the 3D scanning camera 202 are both fixedly mounted on the sampling platform 1, the robotic arm 203 is fixedly mounted on the top inner wall of the frame 201, the vertical arm 204 is fixedly mounted on the bottom of the robotic arm 203, the power motor 205 is fixedly mounted on one vertical arm 204, the output end of the power motor 205 is fixedly connected to the power shaft 206, the outer side of the power shaft 206 is provided with a bidirectional thread, the bidirectional thread is threadedly connected to the slide 207, and the clamping arm 208 is vertically slidably sleeved on the outer side of the slide 207. It should be noted that the clamping arm 208 is heavy and will automatically move downward in a natural state, so that the rope body 209 is in a straight state; A flat plate is fixedly provided on the side of the slide plate 207, and the rope body 209 is fixedly installed between the flat plate and the side plate 210. It should be noted that the flat plate is not shown in the figure; The side plate 210 is fixedly mounted on the side of the clamping arm 208 , and the sampling head 211 is fixedly mounted on the bottom of the robotic arm 203 .
[0043] Through the above-mentioned sampling mechanism 2, the power motor 205 is started, and the power motor 205 drives the power shaft 206 to rotate. When the power shaft 206 rotates, it drives the two slides 207 to move toward each other through the bidirectional thread. The slide 207 drives the clamping arms 208 to move, and the two clamping arms 208 clamp and fix the experimental animal specimen.
[0044] Specifically, refer to Figure 5 、 Figure 10 、 Figure 11 and Figure 12 The auxiliary mechanism 3 includes a hydraulic cylinder 301, a rotating shaft 302, a placing table 303, a blade 304, a positioning groove 305, a collection box 306 and an anti-slip pad 307. The bottom of the hydraulic cylinder 301 is fixedly mounted on the material collection table 1, and the rotating shaft 302 is rotatably mounted on the hydraulic rod of the hydraulic cylinder 301 through a damping washer. The placing table 303 is fixedly mounted on the top of the rotating shaft 302, and the blade 304 is fixedly mounted on the outside of the rotating shaft 302. The positioning groove 305 is opened at the top of the placing table 303, and the bottom of the collection box 306 is fixedly connected to the anti-slip pad 307. The collection box 306 is placed on the top of the collection box 306 through the anti-slip pad 307.
[0045] Through the above-mentioned auxiliary mechanism 1-3, the experimental animal specimen is placed on the top of the placement table 303, and the hydraulic cylinder 301 is started, so that the placement table 303 drives the experimental animal specimen to move up. First, the experimental animal specimen is subjected to three-dimensional scanning imaging processing by the three-dimensional scanning camera 202. After the three-dimensional imaging processing, the size of the experimental animal specimen can be automatically determined by comparing with the data in the database, which is convenient for measurement. Then, the hydraulic cylinder 301 is started again, so that the placement table 303 drives the experimental animal specimen to continue to move up until the top of the placement table 303 contacts the clamping arm 208, and the experimental animal specimen is clamped by the two clamping arms 208. Fix it, then continue to start the hydraulic cylinder 301, so that the placement table 303 pushes the clamping arm 208, and then the clamping arm 208 can drive the experimental animal specimen to move upward until the sampling head 211 samples the experimental animal specimen and obtains the tissue block. After the tissue block sampling is completed, start the hydraulic cylinder 301 to move the placement table 303 to the bottom of the frame 201, take out the remaining experimental animal specimens, and place the collection box 306 on the placement table 303. Add formaldehyde solution into the collection box 306, and start the hydraulic cylinder 301 to make the placement table 303 drive the collection box 306 to move upward, so that the collection box 306 is moved to the bottom of the sampling head 211.
[0046] Specifically, refer to Figure 5 、 Figure 7 and Figure 8 The auxiliary mechanism 2 4 includes a tube body 1 401, a plate body 1 402, a plate body 2 403, an elastic airbag 404, a cylinder 405, a solenoid valve 1 406, a one-way valve 2 407, a horizontal plate 408, a rod body 409, a piston 410, a tube body 2 411 and a one-way valve 1 412. The tube body 1 401 is fixedly mounted on the material head 211 and the robot arm 203. The plate body 1 402 and the plate body 2 403 are both fixedly mounted on the side wall of the frame 201. The elastic airbag 404 is fixedly mounted between the plate body 1 402 and the plate body 2 403. The cylinder 405 and the tube body 1 401 are both fixedly connected to the elastic airbag 404, the solenoid valve 1 406 is installed on the tube body 1 401, the one-way valve 2 407 is installed on the cylinder 405, the cross plate 408 is fixedly installed on the side wall of the frame 201, the rod body 409 is vertically slidably installed on the cross plate 408, the top of the rod body 409 is fixedly connected to the piston 410, the piston 410 is slidingly sealed and installed inside the cylinder 405, the tube body 2 411 is fixedly installed on the piston 410, and the one-way valve 1 412 is fixedly installed on the tube body 2 411.
[0047] Through the auxiliary mechanism 24, when the placement table 303 drives the clamping arm 208 to move upward, the clamping arm 208 will drive the support plate 415 to move, the support plate 415 drives the rod 409 to move, and the rod 409 drives the piston 410 to move. The setting of the one-way valve 1 412 can allow air to enter the cylinder 405, and the setting of the one-way valve 2 407 can allow the air in the cylinder 405 to enter the elastic airbag 404. When the piston 410 moves upward, the air in the cylinder 405 will enter the elastic airbag 404, so that When the elastic airbag 404 expands and the collection box 306 moves to the bottom of the sampling head 211, the solenoid valve 406 is started, and the air in the elastic airbag 404 enters the sampling head 211 through the tube 401, applying a certain air pressure to the inside of the sampling head 211, so that the tissue blocks sampled in the sampling head 211 can be discharged from the inside of the sampling head 211 and discharged into the collection box 306, and immersed in the formaldehyde solution in the collection box 306. Then the hydraulic cylinder 301 is started to move the collection box 306 to the bottom of the frame 201, and the collection box 306 is taken out.
[0048] Specifically, refer to Figure 7 、 Figure 9 and Figure 11 , the auxiliary mechanism 2 4 also includes a tube body 3 413, a solenoid valve 2 414, a support plate 415, a branch pipe 416 and a solenoid valve 3 417, the tube body 3 413 is fixedly mounted on the tube body 1 401, the solenoid valve 2 414 is mounted on the tube body 3 413, the side of the support plate 415 is fixedly connected to a clamping arm 208, the top of the support plate 415 is in contact with the rod 409, the branch pipe 416 is fixedly mounted on the tube body 3 413, the solenoid valve 3 417 is mounted on the branch pipe 416, and the solenoid valve 4 is installed at the bottom of the tube body 3 413. It should be noted that, as Figure 5 As shown, the solenoid valve is not marked in the figure and is located at the lower part of the tube body 413.
[0049] Through the above-mentioned auxiliary mechanism 2 4, when performing a three-dimensional scan on the experimental animal specimen, the hydraulic cylinder 301 is started to align the blade 304 with the bottom of the tube body 3 413, and the solenoid valve 2 414 and the solenoid valve 4 are started to discharge the air in the elastic airbag 404 from the tube body 3 413. The air discharged from the tube body 3 413 will blow the blade 304, causing the blade 304 to rotate, and the blade 304 drives the rotating shaft 302 to rotate, and the rotating shaft 302 drives the placement table 303 to rotate, and the placement table 303 drives the experimental animal specimen to rotate. With the cooperation of the three-dimensional scanning camera 202, the experimental animal specimen can be well three-dimensionally imaged. After the three-dimensional imaging processing, the size of the experimental animal specimen can be automatically determined by comparing with the data in the database, and the measurement is relatively convenient.
[0050] Specifically, refer to Figure 6 、 Figure 14 and Figure 15 The cleaning mechanism 5 includes a cleaning box 501, a positioning block 502, a main pipe 503, an auxiliary pipe 504, a connecting pipe 1 505, a connecting pipe 2 506, a nozzle 1 507, a nozzle 2 508, a cleaning brush 1 509, a cleaning brush 2 510, a rotating part 511, a water storage tank 512, a pump body 513, a water outlet pipe 514 and a water supply pipe 515. The positioning block 502 is fixedly mounted on the bottom of the cleaning box 501, the main pipe 503 is fixedly mounted on the cleaning box 501, the auxiliary pipe 504, the connecting pipe 1 505 and the connecting pipe 2 506 are all fixedly connected to the main pipe 503, the nozzle 1 507 and the cleaning brush 1 509 They are all fixedly mounted on the connecting pipe 1 505, the nozzle 2 508 and the cleaning brush 2 510 are all fixedly mounted on the connecting pipe 2 506, the rotating member 511 is rotatably sleeved on the outside of the material taking head 211 through a damping washer, the water storage tank 512 is opened at the top of the rotating member 511, the pump body 513 is fixedly mounted on the bottom of the rotating member 511, and the bottom of the pump body 513 is fixedly connected to the water outlet pipe 514. It should be noted that the pump body 513 is a small pump powered by its own battery. A sealing ring is installed in the water outlet pipe 514. When the auxiliary pipe 504 is inserted into the water outlet pipe 514, the sealing of the connection can be ensured. The water supply pipe 515 is fixedly installed on the material collection platform 1.
[0051] Through the above-mentioned cleaning mechanism 5, the positioning block 502 on the cleaning box 501 is inserted into the positioning groove 305 on the placement table 303, and the hydraulic cylinder 301 is started, so that the placement table 303 drives the cleaning box 501 to move up until the auxiliary pipe 504 is inserted into the outlet pipe 514. At this time, the branch pipe 416 is aligned with the blade 304, and the pump body 513 and the electromagnetic valve 3 417 are opened. When the electromagnetic valve 3 417 is opened, the air in the elastic airbag 404 will be blown out through the branch pipe 416 and blown on the blade 304, causing the blade 304 to rotate, and then the rotating shaft 302 can drive the placement table 303 to rotate, and the placement table 30 3 drives the cleaning box 501 to rotate. After the pump body 513 is turned on, the cleaning liquid can be sprayed from the nozzle 1 507 and the nozzle 2 508. The cleaning box 501 drives the main pipe 503 to rotate. The main pipe 503 drives the connecting pipe 1 505 and the connecting pipe 2 506 to rotate. The connecting pipe 1 505 drives the nozzle 1 507 and the cleaning brush 1 509 to rotate, so that the outside of the sampling head 211 can be cleaned. The connecting pipe 2 506 drives the nozzle 2 508 and the cleaning brush 2 510 to rotate, so that the inside of the sampling head 211 can be cleaned. After cleaning, the cleaning box 501 can be taken out.
[0052] Specifically, a display screen 6 is installed on the top inner wall of the sampling table 1, and a cleaning pool 7 is installed on the bottom inner wall of the sampling table 1. It should be noted that the display screen 6 is used to display the three-dimensional scanning imaging results, and the cleaning pool 7 is provided to facilitate the staff to perform cleaning work.
[0053] Specifically, an adapting circular hole is opened at the bottom of the frame 201, a moving block is fixedly set on the rear side of the skateboard 207, a moving groove is opened on the inner wall of the rear side of the frame 201, and the moving block is installed in the moving groove for horizontal sliding. It should be noted that the setting of the adapting circular hole facilitates the placement of the platform 303 in and out of the frame 201, and the setting of the moving block can enable the skateboard 207 to move stably in the horizontal direction.
[0054] Specifically, the auxiliary pipe 504, the connecting pipe 1 505 and the connecting pipe 2 506 are all connected to the interior of the main pipe 503, the nozzle 1 507 is connected to the interior of the connecting pipe 1 505, and the nozzle 2 508 is connected to the interior of the connecting pipe 2 506. It should be noted that this facilitates the flow of the cleaning liquid.
[0055] Currently, there is a serious shortage of pathologists in China, especially in primary hospitals. Digital pathology and intelligent technologies can effectively alleviate this human resource shortage by improving the coverage and accuracy of pathological diagnosis through technical means. Shifting from individual labor to clustered and collaborative work methods can help optimize pathology workflows and improve work efficiency. Intelligent, automated sampling systems can quickly and continuously process large numbers of samples, significantly increasing the speed of slide production and shortening report issuance time. Manual sampling can lead to errors due to factors such as operator fatigue and technical differences. Automated systems can precisely control the depth and range of sampling, reducing errors caused by subjective judgment by operators. Automated sampling ensures consistency and standardization of each sampling, improving the quality of pathological sections, which is crucial for subsequent diagnosis and analysis. Automated sampling reduces direct contact between operators and hazardous chemicals and biological samples, improving the safety of the working environment.
[0056] Working principle of the present invention: S1: Place the experimental animal specimen on top of the placement table 303, start the hydraulic cylinder 301, so that the placement table 303 drives the experimental animal specimen to move upward, so that the blade 304 is aligned with the bottom of the tube body 3 413, start the electromagnetic valve 2 414 and the electromagnetic valve 4, so that the air in the elastic airbag 404 is discharged from the tube body 3 413, and the air discharged from the tube body 3 413 will blow the blade 304, so that the blade 304 rotates, and the blade 304 drives the rotating shaft 302 to rotate, and the rotating shaft 302 drives the placement table 303 to rotate, and the placement table 303 drives the experimental animal specimen to rotate. With the cooperation of the three-dimensional scanning camera 202, the experimental animal specimen can be well imaged in three dimensions; S2: Then continue to start the hydraulic cylinder 301, so that the placement table 303 drives the experimental animal specimen to continue to move upward until the top of the placement table 303 contacts the clamping arm 208, and the experimental animal specimen is clamped and fixed by the two clamping arms 208, and then continue to start the hydraulic cylinder 301, so that the placement table 303 pushes the clamping arm 208, and then the clamping arm 208 can drive the experimental animal specimen to move upward until the sampling head 211 samples the experimental animal specimen and obtains the tissue block. After the tissue block sampling is completed, the hydraulic cylinder 301 is started to move the placement table 303 to the bottom of the frame 201, and the remaining experimental animal specimens are taken out, and the collection box 306 is placed on the placement table 303, and formaldehyde solution is added to the collection box 306. The hydraulic cylinder 301 is started to make the placement table 303 drive the collection box 306 to move upward, so that the collection box 306 is moved to the bottom of the sampling head 211; S3: As the placement platform 303 drives the clamping arm 208 to move upward, the clamping arm 208 drives the support plate 415 to move, the support plate 415 drives the rod 409 to move, and the rod 409 drives the piston 410 to move. The setting of the one-way valve 1 412 allows air to enter the cylinder 405, and the setting of the one-way valve 2 407 allows the air in the cylinder 405 to enter the elastic airbag 404. As the piston 410 moves upward, the air in the cylinder 405 enters the elastic airbag 404, causing the elastic airbag 404 to expand. S4: When the collection box 306 is moved to the bottom of the sampling head 211, the solenoid valve 406 is activated, and the air in the elastic airbag 404 enters the sampling head 211 through the tube 401, exerting a certain air pressure on the inside of the sampling head 211. This allows the tissue blocks sampled in the sampling head 211 to be discharged from the inside of the sampling head 211 and discharged into the collection box 306, where they are immersed in the formaldehyde solution in the collection box 306. Then, the hydraulic cylinder 301 is activated, and the collection box 306 is moved to the bottom of the frame 201, and the collection box 306 is removed. S5: Insert the positioning block 502 on the cleaning box 501 into the positioning groove 305 on the placement table 303, start the hydraulic cylinder 301, and make the placement table 303 drive the cleaning box 501 to move upward until the auxiliary pipe 504 is inserted into the water outlet pipe 514. At this time, the branch pipe 416 is aligned with the blade 304. Open the pump body 513 and the electromagnetic valve 3 417. When the electromagnetic valve 3 417 is turned on, the air in the elastic airbag 404 will be blown out through the branch pipe 416 and blown onto the blade 304, causing the blade 304 to rotate, thereby causing the rotating shaft 302 to drive the placement table 303 to rotate; S6: The placement table 303 drives the cleaning box 501 to rotate. After the pump body 513 is turned on, the cleaning liquid can be sprayed out from the nozzle 1 507 and the nozzle 2 508. The cleaning box 501 drives the main pipe 503 to rotate. The main pipe 503 drives the connecting pipe 1 505 and the connecting pipe 2 506 to rotate. The connecting pipe 1 505 drives the nozzle 1 507 and the cleaning brush 1 509 to rotate, so that the outside of the sampling head 211 can be cleaned. The connecting pipe 2 506 drives the nozzle 2 508 and the cleaning brush 2 510 to rotate, so that the inside of the sampling head 211 can be cleaned. After cleaning, the hydraulic cylinder 301 is started to move the cleaning box 501 to the bottom of the frame 201. Finally, the cleaning box 501 can be taken out. In this way, the experimental animal specimens can be intelligently processed and the sampling efficiency can be effectively improved.
[0057] The above describes in detail the intelligent biological sample measurement and sampling device provided by the present invention. Specific embodiments are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is intended only to facilitate understanding of the method and core concepts of the present invention. It should be noted that those skilled in the art may make various improvements and modifications to the present invention without departing from the principles of the present invention, and such improvements and modifications fall within the scope of protection of the claims of the present invention.
Claims
1. An intelligent biological sample measurement and sampling device, characterized in that: include: A material collection platform (1), wherein the material collection platform (1) is provided with a material collection mechanism (2), an auxiliary mechanism 1 (3), an auxiliary mechanism 2 (4) and a cleaning mechanism (5); The material collection mechanism (2) includes a frame (201), a three-dimensional scanning camera (202), a mechanical arm (203), a vertical arm (204), a power motor (205), a power shaft (206), a slide (207), a clamping arm (208), a rope body (209), a side plate (210) and a material collection head (211); The frame (201) and the three-dimensional scanning camera (202) are both fixedly mounted on the material collection platform (1), the mechanical arm (203) is fixedly mounted on the top inner wall of the frame (201), the vertical arm (204) is fixedly mounted on the bottom of the mechanical arm (203), the power motor (205) is fixedly mounted on one vertical arm (204), the output end of the power motor (205) is fixedly connected to the power shaft (206), the outer side of the power shaft (206) is provided with a bidirectional thread, and the bidirectional thread is threadedly connected to the slide (207), the clamping arm (208) is vertically slidably sleeved on the outer side of the slide (207), a flat plate is fixedly provided on the side of the slide (207), the rope body (209) is fixedly mounted between the flat plate and the side plate (210), the side plate (210) is fixedly mounted on the side of the clamping arm (208), and the material collection head (211) is fixedly mounted on the bottom of the mechanical arm (203).
2. The intelligent biological sample measurement and sampling device according to claim 1, characterized in that: The auxiliary mechanism (3) comprises a hydraulic cylinder (301), a rotating shaft (302), a placing table (303), a blade (304), a positioning groove (305), a collection box (306) and an anti-skid pad (307). The bottom of the hydraulic cylinder (301) is fixedly mounted on the material collection table (1). The rotating shaft (302) is rotatably mounted on the hydraulic rod of the hydraulic cylinder (301) through a damping washer. The placing table (303) is fixedly mounted on the top of the rotating shaft (302). The blade (304) is fixedly mounted on the outside of the rotating shaft (302). The positioning groove (305) is opened on the top of the placing table (303). The bottom of the collection box (306) is fixedly connected to the anti-skid pad (307). The collection box (306) is placed on the top of the collection box (306) through the anti-skid pad (307).
3. The intelligent biological sample measurement and sampling device according to claim 1, characterized in that: The auxiliary mechanism 2 (4) includes a tube body 1 (401), a plate body 1 (402), a plate body 2 (403), an elastic airbag (404), a cylinder (405), an electromagnetic valve 1 (406), a one-way valve 2 (407), a horizontal plate (408), a rod body (409), a piston (410), a tube body 2 (411) and a one-way valve 1 (412), wherein the tube body 1 (401) is fixedly mounted on the material collecting head (211) and the robot arm (203), the plate body 1 (402) and the plate body 2 (403) are both fixedly mounted on the side wall of the frame (201), the elastic airbag (404) is fixedly mounted between the plate body 1 (402) and the plate body 2 (403), the cylinder The body (405) and the tube body 1 (401) are both fixedly connected to the elastic airbag (404), the solenoid valve 1 (406) is installed on the tube body 1 (401), the one-way valve 2 (407) is installed on the cylinder (405), the cross plate (408) is fixedly installed on the side wall of the frame (201), the rod body (409) is vertically slidably installed on the cross plate (408), the top of the rod body (409) is fixedly connected to the piston (410), and the piston (410) is slidingly sealed and installed inside the cylinder (405), the tube body 2 (411) is fixedly installed on the piston (410), and the one-way valve 1 (412) is fixedly installed on the tube body 2 (411).
4. The intelligent biological sample measurement and sampling device according to claim 3, characterized in that: The auxiliary mechanism 2 (4) also includes a tube body 3 (413), a solenoid valve 2 (414), a support plate (415), a branch pipe (416) and a solenoid valve 3 (417), wherein the tube body 3 (413) is fixedly mounted on the tube body 1 (401), the solenoid valve 2 (414) is mounted on the tube body 3 (413), the side of the support plate (415) is fixedly connected to a clamping arm (208), the top of the support plate (415) is in contact with the rod body (409), the branch pipe (416) is fixedly mounted on the tube body 3 (413), the solenoid valve 3 (417) is mounted on the branch pipe (416), and the solenoid valve 4 is mounted at the bottom of the tube body 3 (413).
5. The intelligent biological sample measurement and sampling device according to claim 1, characterized in that: The cleaning mechanism (5) comprises a cleaning box (501), a positioning block (502), a main pipe (503), an auxiliary pipe (504), a connecting pipe 1 (505), a connecting pipe 2 (506), a nozzle 1 (507), a nozzle 2 (508), a cleaning brush 1 (509), a cleaning brush 2 (510), a rotating member (511), a water storage tank (512), a pump body (513), a water outlet pipe (514) and a water supply pipe (515), wherein the positioning block (502) is fixedly mounted on the bottom of the cleaning box (501), the main pipe (503) is fixedly mounted on the cleaning box (501), the auxiliary pipe (504), the connecting pipe 1 (505) and the connecting pipe 2 ( 506) are fixedly connected to the main pipe (503), the nozzle one (507) and the cleaning brush one (509) are fixedly installed on the connecting pipe one (505), the nozzle two (508) and the cleaning brush two (510) are fixedly installed on the connecting pipe two (506), the rotating member (511) is rotatably sleeved on the outside of the material collection head (211) through a damping washer, the water storage tank (512) is opened at the top of the rotating member (511), the pump body (513) is fixedly installed on the bottom of the rotating member (511), the bottom of the pump body (513) is fixedly connected to the water outlet pipe (514), and the water supply pipe (515) is fixedly installed on the material collection table (1).
6. The intelligent biological sample measurement and sampling device according to claim 1, characterized in that: A display screen (6) is installed on the inner wall of the top of the material collection platform (1), and a cleaning pool (7) is installed on the inner wall of the bottom of the material collection platform (1).
7. The intelligent biological sample measurement and sampling device according to claim 1, characterized in that: The bottom of the frame (201) is provided with an adapting circular hole.
8. The intelligent biological sample measurement and sampling device according to claim 1, characterized in that: A moving block is fixedly provided on the rear side of the slide plate (207), a moving groove is provided on the inner wall of the rear side of the frame (201), and the moving block is installed in the moving groove in a transversely sliding manner.
9. The intelligent biological sample measurement and sampling device according to claim 5, characterized in that: The auxiliary pipe (504), connecting pipe 1 (505) and connecting pipe 2 (506) are all connected to the interior of the main pipe (503).
10. The intelligent biological sample measurement and sampling device according to claim 5, characterized in that: The nozzle 1 (507) is connected to the interior of the connecting pipe 1 (505), and the nozzle 2 (508) is connected to the interior of the connecting pipe 2 (506).
Citation Information
Patent Citations
Biological sample sampling table
CN219454892U