Development and application of hemorrhoid treatment auxiliary shorts capable of supplying medicine to hemorrhoid recovery products and capable of being repeatedly used

Abstract

The invention relates to development and application of hemorrhoid treatment auxiliary shorts capable of supplying medicine to hemorrhoid recovery products and capable of being repeatedly used, and belongs to the technical field of medical care. The main drug product is prepared by compounding nanocarbon, marine active substances (algal polysaccharides and chitin), dragon's blood, borneol, gallnut, coptis chinensis, golden cypress, frankincense, myrrh, calamine, dried alum, aloe and the like, and the targeting property and permeability are enhanced through a nanotechnology; the health-care shorts adopt a detachable medicine bag design, and a slow-release layer and a temperature-sensitive gel layer are arranged in the medicine bag, so that the health-care shorts can adapt to main medicine products (paste, powder and gel) in different dosage forms. The shorts body is made of graphene blended fabric and has the functions of bacteriostasis, self-adaptive pressurization and temperature adjustment. The traditional Chinese medicine is combined with the modern nanotechnology and intelligent wearing, the problems that an existing hemorrhoid treatment medicine is poor in absorption and shorts are single in function are solved, clinical data show that the total effective rate reaches 96.5%, and side effects are avoided.

Description

Technical Field

[0001] The present invention relates to the field of medical care technology, and specifically to a hemorrhoid treatment system that integrates a nano-traditional Chinese medicine formula with smart wearable technology, comprising a special main medicine and matching reusable treatment shorts. Background Art

[0002] Existing hemorrhoid treatments face the following challenges: 1) While traditional ointments (such as CN1810281A) have some efficacy, they suffer from poor drug penetration, making them difficult to target at the lesion; 2) Medicated pants (such as CN1087832A) often utilize fixed medication bags, which are inadequate for adapting to different treatment stages; and 3) Smart hemorrhoid pants (such as the Zhongzhi Zhikui) focus on physical pressure application, and currently available trial samples lack drug-device collaboration. Furthermore, the use of marine active ingredients in existing medications, beyond our proprietary Haina and Baina Zhikang products, has not been reported. However, research has shown that seaweed polysaccharides and chitin have significant anti-inflammatory and tissue repair effects. Summary of the Invention

[0003] The present invention proposes the following innovative solutions: 1. Main ingredients: Nano-carbon carriers are used to enhance drug permeability, and marine active substances are compounded to enhance antibacterial and anti-inflammatory effects. The ingredients are in line with the principles of hemorrhoid treatment recorded in the Compendium of Materia Medica (such as Sanguisorba officinalis for blood circulation and Gallnut for astringency).

[0004] 1. Health Shorts: - Removable medicine chamber design supports switching between multiple dosage forms such as ointments, powders, and gels; - Thermosensitive gel layer enables body temperature-triggered drug release; - Graphene fabric provides antibacterial and dynamic compression functions. DETAILED DESCRIPTION

[0005] Example 1-Preparation of the main drug: Take 6g of nanocarbon, 12g of seaweed polysaccharide, 10g of chitin, 9g of dragon's blood, 7g of borneol, 6g of gallnut, 5g of coptis root, 5g of phellodendron, 6g of frankincense, 6g of myrrh, 4g of calamine, 4g of alum, and 18g of aloe. Grind the nanocarbon with the borneol first, then mix with the other components, add vaseline to 100g, and homogenize to obtain an ointment.

[0006] Example 2 - Shorts Use: The ointment is applied to the sustained-release non-woven fabric of the drug reservoir. After wearing, the pressure mode is set through the APP (such as selecting the strong mode after defecation). The thermosensitive gel layer liquefies at body temperature to promote drug release, and the pH microcapsules rupture in the acidic environment of the anus to achieve precise drug delivery.

[0007] The experiment was carried out in the resource hospital cooperating with Shanxi Tongwen Vocational and Technical College: - Grouping: experimental group (this product) 100 cases, control group (traditional ointment + ordinary shorts) 100 cases; - Results: The pain relief rate in the experimental group was 92% within 7 days (65% in the control group), and the cure rate was 88% within 14 days (52% in the control group). No case of skin allergy occurred. BRIEF DESCRIPTION OF THE DRAWINGS

[0008] Figure 1-3 It is a schematic diagram showing the shorts structure, medicine chamber layering and intelligent control process.

Claims

1. A proprietary formula medicine, characterized by The invention is composed of the following components in percentage by weight: 5-8% nano carbon, 10-15% seaweed polysaccharide, 8-12% chitin, 8-10% dragon's blood, 6-8% borneol, 5-7% gallnut, 4-6% coptis root, 4-6% phellodendron, 5-7% frankincense, 5-7% myrrh, 3-5% calamine, 3-5% alum, 15-20% aloe, and the balance is medical vaseline or gel matrix.

2. The exclusive formula medicine according to claim 1, characterized in that: The marine active substance is sulfated polysaccharide extracted from deep-sea brown algae, and its molecular weight is controlled at 10-50 kDa; the nanocarbon is multi-walled carbon nanotubes modified by carboxylation, and its particle size is 20-50 nm.

3. A replaceable and reusable health-care hemorrhoid-treating shorts implementing the main product of claims 1-2, comprising a shorts body (1), characterized in that: - A detachable medicine compartment (2) is provided on the inner side of the crotch of the shorts body (1), and the medicine compartment (2) is fixed by a Velcro (3) or a magnetic buckle (4); - The drug storage chamber (2) is a three-layer structure, comprising an outer breathable antibacterial mesh (5), a middle thermosensitive gel layer (6), and an inner drug-release non-woven fabric (7); The shorts body (1) is made of a graphene blended fabric, and the fabric contains an embedded micro pressure sensor (8) and a heating unit (9).

4. The health-care hemorrhoid-treating shorts according to claim 3, characterized in that: The thermosensitive gel layer (6) is a composite of poly (N-isopropylacrylamide) (PNIPAM) and chitosan, and its phase transition temperature is 32-36°C.

5. The health-care hemorrhoid-treating shorts according to claim 3, characterized in that: The waist of the shorts body (1) is provided with an intelligent control module (10), which can adjust the pressure intensity and heating temperature via a Bluetooth connection to a mobile terminal, and the control module (10) is powered by a flexible battery (11).

6. The health-care hemorrhoid-treating shorts according to claim 3, characterized in that: The surface of the drug sustained-release nonwoven fabric (7) is coated with pH-responsive microcapsules (12), and the main drug according to claims 1-2 is encapsulated in the microcapsules.

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