Additive for improving quality and yield of cashmere of cashmere goats

Abstract

The invention relates to the technical field of feed additives, in particular to an additive for improving the quality and yield of cashmere of cashmere goats. The feed is prepared from the following raw materials in parts by weight: 20-30 parts of green feed, 12-15 parts of modified zinc-copper composite mineral substances, 12-18 parts of mixed fermentation bacteria liquid, 5-8 parts of organic acid, 3-5 parts of liquorice roots, 3-5 parts of jasmine flower residues, 3-4 parts of gynostemma pentaphyllum polysaccharide, 2-8 parts of vitamins, 3-5 parts of corn straws and 0.5-1.5 parts of melatonin. The mixed zymophyte liquid is a mixed liquid of bacillus subtilis fermentation liquid and saccharomycetes fermentation liquid. The prepared additive gives consideration to the yield, quality and health of the down producing goats through multiple ways such as nutrition regulation and control, hormone balance and hair follicle activation, and has remarkable economic and ecological values.

Description

Technical Field

[0001] The invention relates to the technical field of feed additives, and more particularly to an additive for improving the quality and yield of cashmere goat wool. Background Art

[0002] Cashmere is a thin layer of fine wool that grows on the outer layer of a goat's skin, hidden beneath the coarse hair. It grows in the cold of winter to protect against the chill and sheds in the spring when the weather warms, naturally adapting to the climate. Cashmere is a rare and specialized animal fiber. Its value lies not only in its rarity (accounting for only 0.2% of the world's total animal fiber production), but more importantly, in its exceptional quality and properties. Priced by the gram, it is considered the "fiber gem" and "fiber queen," unmatched by any other textile raw material currently available to humanity, earning it the nickname "soft gold." Approximately 70% of the world's cashmere is produced in China, where its quality is superior to that of other countries.

[0003] Cashmere goats are typically raised in high-altitude, cold regions. They have a thick, long outer coat and a soft, downy undercoat, which sheds naturally between spring and summer. During the shedding season, breeders typically use a metal comb to extract the down. The down undergoes preliminary processing and combing to remove coarse hair, impurities, and dust. The resulting clean, fine down is called "hair-free cashmere." The coarse hair content of the clean cashmere is typically less than 0.5%. Cashmere goats are highly adaptable and have stable genetic traits.

[0004] The long-term use of antibiotics in cashmere goat feed to improve feed utilization, immunity and animal production performance has caused cashmere goats to produce drug-resistant bacteria, affecting the growth and cashmere production of yak cashmere goats, and easily affecting human health. Summary of the Invention

[0005] The present invention provides an additive for improving the quality and yield of cashmere goat wool. The prepared additive takes into account the yield, quality and health of cashmere goats through multiple pathways such as nutritional regulation, hormone balance and hair follicle activation, and has significant economic and ecological value.

[0006] In a first aspect, the present invention provides an additive for improving the quality and yield of cashmere goat wool, which is prepared from the following raw materials in parts by weight: 20-30 parts of green fodder, 12-15 parts of modified zinc-copper composite minerals, 12-18 parts of mixed fermentation bacterial liquid, 5-8 parts of organic acid, 3-5 parts of licorice, 3-5 parts of jasmine residue, 3-4 parts of Gynostemma pentaphyllum polysaccharide, 2-8 parts of vitamins, 3-5 parts of corn straw, and 0.5-1.5 parts of melatonin; the mixed fermentation bacterial liquid is a mixture of Bacillus subtilis fermentation liquid and yeast fermentation liquid.

[0007] Preferably, it is prepared from the following raw materials in parts by weight: 22-30 parts of green fodder, 13-15 parts of modified zinc-copper complex minerals, 13-18 parts of mixed fermentation bacteria liquid, 6-8 parts of organic acid, 3-5 parts of licorice, 3-5 parts of jasmine residue, 3-4 parts of Gynostemma pentaphyllum polysaccharide, 5-8 parts of vitamins, 3-5 parts of corn straw, and 0.5-1.5 parts of melatonin.

[0008] Preferably, it is prepared from the following raw materials in parts by weight: 25-30 parts of green fodder, 12-15 parts of modified zinc-copper complex minerals, 15-18 parts of mixed fermentation bacteria liquid, 6-8 parts of organic acid, 4-5 parts of licorice, 4-5 parts of jasmine residue, 3-4 parts of Gynostemma pentaphyllum polysaccharide, 5-8 parts of vitamins, 4-5 parts of corn straw, and 1.0-1.5 parts of melatonin.

[0009] Preferably, it is prepared from the following raw materials in parts by weight: 28-30 parts of green fodder, 14-15 parts of modified zinc-copper complex minerals, 16-18 parts of mixed fermentation bacteria liquid, 7-8 parts of organic acid, 4-5 parts of licorice, 4-5 parts of jasmine residue, 3-4 parts of Gynostemma pentaphyllum polysaccharide, 2-8 parts of vitamins, 3-5 parts of corn straw, and 0.5-1.5 parts of melatonin.

[0010] Preferably, it is prepared from the following raw materials in parts by weight: 20 parts of green fodder, 12 parts of modified zinc-copper complex minerals, 12 parts of mixed fermentation bacteria liquid, 5 parts of organic acid, 3 parts of licorice, 3 parts of jasmine residue, 3 parts of Gynostemma pentaphyllum polysaccharide, 2 parts of vitamins, 3 parts of corn stalks, and 0.5 parts of melatonin.

[0011] Preferably, it is prepared from the following raw materials in parts by weight: 25 parts of green fodder, 13 parts of modified zinc-copper complex minerals, 15 parts of mixed fermentation bacteria liquid, 7 parts of organic acid, 4 parts of licorice, 4 parts of jasmine residue, 3 parts of Gynostemma pentaphyllum polysaccharide, 7 parts of vitamins, 4 parts of corn straw, and 1.0 part of melatonin.

[0012] Preferably, the mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth is 1-3:1-2.

[0013] Preferably, the mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth is 2-3:1-2.

[0014] Preferably, the mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth is 3:2.

[0015] Preferably, the mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth is 1:2.

[0016] Preferably, the mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth is 3:1.

[0017] Preferably, the effective viable bacteria count of the mixed fermentation broth is 1.5×10 10 -5×10 10 CFU / mL.

[0018] Preferably, the effective viable bacteria count of the mixed fermentation broth is 2.5×10 10 -5×10 10 CFU / mL.

[0019] Preferably, the effective viable bacteria count of the mixed fermentation broth is 3.5×10 10 -5×10 10 CFU / mL.

[0020] Preferably, the effective viable bacteria count of the mixed fermentation broth is 4.5×10 10 -5×10 10 CFU / mL.

[0021] Preferably, the effective viable bacteria count of the mixed fermentation broth is 3.8×10 10 CFU / mL.

[0022] Preferably, the modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles, which are prepared by mixing cystine as a sulfur source and surface modifier with copper sulfate and zinc nitrate in an aqueous solution and then subjecting the mixture to heat treatment. The mass ratio of cystine, copper sulfate and zinc nitrate is 1-3:1-2:3-5.

[0023] Preferably, the modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles, which are prepared by mixing cystine as a sulfur source and surface modifier with copper sulfate and zinc nitrate in an aqueous solution and then subjecting the mixture to heat treatment. The mass ratio of cystine, copper sulfate and zinc nitrate is 2-3:1-2:3-5.

[0024] Preferably, the modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles, which are prepared by mixing cystine as a sulfur source and surface modifier with copper sulfate and zinc nitrate in an aqueous solution and then subjecting the mixture to heat treatment. The mass ratio of cystine, copper sulfate and zinc nitrate is 1:1:3.

[0025] Preferably, the modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles, which are prepared by mixing cystine as a sulfur source and surface modifier with copper sulfate and zinc nitrate in an aqueous solution and then subjecting the mixture to heat treatment. The mass ratio of cystine, copper sulfate and zinc nitrate is 2:1:3.

[0026] Preferably, the modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles, which are prepared by mixing cystine as a sulfur source and surface modifier with copper sulfate and zinc nitrate in an aqueous solution and then subjecting the mixture to heat treatment. The mass ratio of cystine, copper sulfate and zinc nitrate is 3:2:5.

[0027] Preferably, the green fodder is one or more of vegetable leaves, weeds, pasture grass or tree leaves.

[0028] Preferably, the organic acid is one of citric acid, malic acid and fumaric acid.

[0029] Preferably, the vitamin is one or more of vitamin A, vitamin E or vitamin D3.

[0030] In a second aspect, the present invention provides a method for preparing an additive for improving the quality and yield of cashmere goat wool, comprising the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) Add the mixed fermentation liquid to the preform, mix evenly, let it stand for 8-12 hours, and then ventilate and dry at 50-80°C to obtain an additive for improving the quality and yield of cashmere goat wool.

[0031] In a third aspect, the present invention provides a use of an additive for improving the quality and yield of cashmere goat wool in the preparation of cashmere goat breeding feed.

[0032] Preferably, the mixed breeding feed is a feed that improves the quality and yield of cashmere goat wool.

[0033] In summary, the present invention has the following beneficial effects: 1. The green fodder added in the present invention can be one or more of vegetable leaves, weeds, pasture grasses, or tree leaves. The high protein (leguminous pastures contain 18%-24% crude protein per dry matter) and vitamins in the green fodder help maintain goat health, promote hair follicle development, and improve fur quality. When used in conjunction with additives (such as anthelmintic health supplements), it can reduce damage to fur caused by external parasites, further increasing yield.

[0034] 2. The modified zinc-copper composite mineral incorporated into the present invention is cystine-modified copper / zinc sulfide nanoparticles. Cystine-modified copper / zinc sulfide nanoparticles are prepared by mixing copper sulfate and zinc nitrate in an aqueous solution with cystine as a sulfur source and surface modifier, followed by heat treatment. Minerals such as zinc, copper, and sulfur are essential elements for cashmere goat hair growth. Zinc is involved in hair follicle development and fiber growth; zinc deficiency can lead to follicle degeneration and reduced hair yield. Copper affects wool / cashmere pigmentation and fiber strength, while synergistically working with zinc to improve production performance. Sulfur is a core component of keratin synthesis (keratin makes up 90% of cashmere fiber), while cystine and cysteine ​​are sulfur-rich amino acids in keratin. Dietary supplementation with cystine, a sulfur-containing substance, can significantly increase cashmere yield and sulfur content. Cystine modification of copper / zinc sulfide nanoparticles imparts antioxidant properties and enhances their stability. The high specific surface area of ​​the nanoparticles may increase mineral bioavailability and promote hair follicle absorption. Cystine, as a sulfur source, directly provides cysteine, which is required for keratin synthesis. Supplementing sulfur-containing compounds can increase the cysteine ​​and sulfur content in cashmere fibers and promote cashmere growth.

[0035] 3. The present invention incorporates Bacillus subtilis fermentation broth and yeast fermentation broth into the mixed fermentation broth. Bacillus subtilis secretes proteases, amylases, and lipases, breaking down complex carbohydrates, improving feed nutrient utilization, increasing serum superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities, reducing malondialdehyde (MDA) concentrations, and mitigating the negative effects of oxidative stress on villus growth. Saccharomyces cerevisiae stabilizes rumen pH, increases ammonia nitrogen concentration and volatile fatty acid (VFA) production, and improves cellulose digestibility. Under heat stress conditions, the combination of yeast and Bacillus subtilis significantly improves goat digestibility of dry matter, neutral detergent fiber (NDF), and acid detergent fiber (ADF).

[0036] 4. The addition of jasmine flower residue in the present invention significantly improves the apparent digestibility of acid detergent fiber and increases the relative abundance of fiber-degrading bacteria (such as Succinolytica and Prevotella) in the rumen, thereby optimizing goats' digestion and utilization of fiber. Jasmine flower residue provides an optimal physiological environment for villi growth by enhancing immunity, antioxidant capacity, and nutrient absorption efficiency. A healthy body is the foundation for high-quality villi production. The active ingredients in jasmine flower residue (such as flavonoids and polysaccharides) may indirectly influence hair follicle development and the villi growth cycle through epigenetic or signaling pathways (such as Wnt / β-catenin). As a feed additive, jasmine flower residue indirectly improves the health of cashmere goats by reducing breeding costs, enhancing fiber digestion, and boosting antioxidant and immune functions, thereby creating favorable conditions for improving villi quality and yield. Its active ingredients may exert their effects by regulating genes or signaling pathways related to hair follicle development.

[0037] 5. The gynostemma pentaphyllum polysaccharide added in the present application can significantly enhance the immunity of the animal body, strengthen the immune system function by activating NK cells (natural killer cells) and promoting lymphocytes to secrete interleukins, and improve the intestinal morphology (such as increasing the villus height and reducing the crypt depth) and nutrient digestion rate. It is suitable for cashmere goats, reduces the interruption of cashmere growth caused by diseases by enhancing the disease resistance, and indirectly improves the yield and quality of cashmere. The gynostemma pentaphyllum polysaccharide has significant antioxidant activity, can scavenge free radicals and inhibit lipid peroxidation. The addition of plant polysaccharides (such as astragalus polysaccharides) to the daily diet of goats can improve the serum antioxidant indexes (such as increasing the activities of SOD and GSH-Px). For cashmere goats, the enhancement of antioxidant capacity helps to alleviate the damage of environmental or metabolic stress to hair follicle cells, thereby maintaining the normal growth cycle and fiber strength of cashmere. The core advantage of gynostemma pentaphyllum polysaccharide as an additive lies in the indirect improvement of the health level and production performance of cashmere goats through the three mechanisms of immune enhancement, antioxidant protection and nutrition optimization, thereby improving the yield and quality of cashmere.

[0038] 6. The melatonin added in the present application can regulate nitrogen distribution (promote nitrogen transfer to cashmere), activate antioxidant pathways, and optimize hair follicle development mechanisms, thereby improving cashmere yield (especially in non-cashmere growing seasons), improving fiber fineness, length and density, and having significant economic and ecological values.

[0039] It should be understood that the above general description and the following detailed description are only exemplary and explanatory, and cannot limit the protection scope of the present application. DETAILED DESCRIPTION

[0040] The present application will be further described in detail below in combination with examples, and it is particularly stated that: in the following examples, the specific conditions are not specified, and the conventional conditions or the conditions recommended by the manufacturers are used, and the raw materials used in the following examples can be obtained from ordinary market sales unless otherwise specified.

[0041] EXAMPLE Example 1

[0042] An additive for improving the quality and yield of cashmere of cashmere goats is prepared from the following raw materials in parts by weight: 20 parts of green forage, 12 parts of modified zinc-copper composite mineral, 12 parts of mixed fermentation bacteria liquid, 5 parts of organic acid, 3 parts of licorice, 3 parts of jasmine residue, 3 parts of gynostemma pentaphyllum polysaccharide, 2 parts of vitamin, 3 parts of corn straw, and 0.5 parts of melatonin.

[0043] The mass ratio of bacillus subtilis fermentation broth and yeast fermentation broth in the mixed fermentation bacteria liquid is 1:2; the effective viable count of the mixed fermentation bacteria liquid is 1.5 x 10 10 CFU / mL.

[0044] The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution and then prepared by heat treatment. The heat treatment conditions are a reaction temperature of 130°C, a reaction time of 10 hours, and a mass ratio of cystine, copper sulfate and zinc nitrate of 1:1:3.

[0045] Green fodder is vegetable leaves.

[0046] The organic acid is citric acid.

[0047] The vitamin is vitamin A, vitamin E or vitamin D3.

[0048] A method for preparing an additive for improving the quality and yield of cashmere goat wool comprises the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) The mixed fermentation liquid is added to the preform, mixed evenly, and then allowed to stand for 8 hours, and then ventilated and dried at 50°C to obtain an additive for improving the quality and yield of cashmere goat wool. Example 2

[0049] An additive for improving the quality and yield of cashmere goat wool is prepared from the following raw materials in parts by weight: 22 parts of green fodder, 12 parts of modified zinc-copper composite minerals, 13 parts of mixed fermentation bacterial liquid, 5 parts of organic acid, 3 parts of liquorice, 3 parts of jasmine flower residue, 3 parts of gynostemma pentaphyllum polysaccharide, 2 parts of vitamins, 3 parts of corn straw, and 0.5 parts of melatonin.

[0050] The mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth was 2:1; the effective viable cell count of the mixed fermentation broth was 2.5×10 10 CFU / mL.

[0051] The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution and then prepared by heat treatment. The heat treatment conditions are a reaction temperature of 130°C, a reaction time of 10 hours, and a mass ratio of cystine, copper sulfate and zinc nitrate of 1:1:4.

[0052] Green fodder is wild grass.

[0053] The organic acid is citric acid.

[0054] The vitamin is vitamin A, vitamin E or vitamin D3.

[0055] A preparation method of an additive for improving cashmere quality and yield of cashmere goats, comprising the following steps: (1) proportionally weighing and mixing green fodder, modified zinc-copper composite mineral, organic acid, liquorice, jasmine residue, gypenoside, vitamin, corn straw and melatonin to prepare a preform; (2) adding mixed fermentation liquor into the preform, uniformly mixing, standing for 9 hours, and then drying under the condition of 50 DEG C ventilation to prepare the additive for improving cashmere quality and yield of cashmere goats. Example 3

[0056] An additive for improving cashmere quality and yield of cashmere goats is prepared from the following raw materials in parts by weight: 23 parts of green fodder, 13 parts of modified zinc-copper composite mineral, 14 parts of mixed fermentation liquor, 5 parts of organic acid, 3 parts of liquorice, 3 parts of jasmine residue, 3 parts of gypenoside, 2 parts of vitamin, 3 parts of corn straw and 0.5 parts of melatonin.

[0057] The mass ratio of Bacillus subtilis fermentation liquor and yeast fermentation liquor in the mixed fermentation liquor is 1:1; the effective viable count of the mixed fermentation liquor is 3.5x10 10 CFU / mL.

[0058] The modified zinc-copper composite mineral is a cystine modified copper / zinc sulfide nanoparticle, which is prepared by mixing cystine, copper sulfate and zinc nitrate in an aqueous solution and then heat treating under the condition of a reaction temperature of 130 DEG C and a reaction time of 10 hours, with the mass ratio of cystine, copper sulfate and zinc nitrate being 1:1:5.

[0059] The green fodder is pasture.

[0060] The organic acid is malic acid.

[0061] The vitamin is vitamin A and vitamin E.

[0062] A preparation method of an additive for improving cashmere quality and yield of cashmere goats, comprising the following steps: (1) proportionally weighing and mixing green fodder, modified zinc-copper composite mineral, organic acid, liquorice, jasmine residue, gypenoside, vitamin, corn straw and melatonin to prepare a preform; (2) adding mixed fermentation liquor into the preform, uniformly mixing, standing for 10 hours, and then drying under the condition of 50 DEG C ventilation to prepare the additive for improving cashmere quality and yield of cashmere goats. Example 4

[0063] The additive for improving cashmere quality and yield of cashmere goats is prepared from the following raw materials in parts by weight: 22 parts of green fodder, 12 parts of modified zinc-copper composite mineral, 12 parts of mixed fermentation liquid, 5 parts of organic acid, 3 parts of licorice, 3 parts of jasmine residue, 3 parts of gypenoside, 2 parts of vitamin, 3 parts of corn straw, and 0.8 parts of melatonin.

[0064] The mass ratio of the Bacillus subtilis fermentation liquid and the yeast fermentation liquid in the mixed fermentation liquid is 1:2; the effective viable count of the mixed fermentation liquid is 1.5 x 10 10 CFU / mL.

[0065] The modified zinc-copper composite mineral is a cystine-modified copper / zinc sulfide nanoparticle, which is prepared by mixing cystine, copper sulfate and zinc nitrate in an aqueous solution and then performing heat treatment, wherein the reaction temperature is 130 DEG C, the reaction time is 10 h, and the mass ratio of cystine, copper sulfate and zinc nitrate is 1:2:3.

[0066] The green fodder is tree leaves.

[0067] The organic acid is malic acid.

[0068] The vitamin is vitamin A and vitamin E.

[0069] A preparation method of an additive for improving cashmere quality and yield of cashmere goats, comprising the following steps: (1) mixing green fodder, modified zinc-copper composite mineral, organic acid, licorice, jasmine residue, gypenoside, vitamin, corn straw and melatonin in proportion to prepare a preform; (2) adding mixed fermentation liquid to the preform, uniformly mixing, standing for 8 h, and then performing ventilation drying at 50 DEG C to prepare the additive for improving cashmere quality and yield of cashmere goats. Example 5

[0070] An additive for improving cashmere quality and yield of cashmere goats is prepared from the following raw materials in parts by weight: 25 parts of green fodder, 13 parts of modified zinc-copper composite mineral, 15 parts of mixed fermentation liquid, 6 parts of organic acid, 4 parts of licorice, 4 parts of jasmine residue, 3 parts of gypenoside, 3 parts of vitamin, 4 parts of corn straw, and 1.0 parts of melatonin.

[0071] The mass ratio of the Bacillus subtilis fermentation liquid and the yeast fermentation liquid in the mixed fermentation liquid is 1:1; the effective viable count of the mixed fermentation liquid is 2.0 x 10 10 CFU / mL.

[0072] The modified zinc-copper composite mineral is a cystine-modified copper / zinc sulfide nanoparticle, the cystine-modified copper / zinc sulfide nanoparticle is prepared by mixing cystine, copper sulfate and zinc nitrate in an aqueous solution and then performing heat treatment, the heat treatment is performed under the condition that the reaction temperature is 130 DEG C, the reaction time is 10 h, and the mass ratio of cystine, copper sulfate and zinc nitrate is 2:1:3.

[0073] The green forage is a vegetable leaf.

[0074] The organic acid is citric acid.

[0075] The vitamin is vitamin A, vitamin E or vitamin D3.

[0076] A preparation method of an additive for improving the quality and yield of cashmere of a cashmere goat, comprising the following steps: (1) mixing green forage, modified zinc-copper composite mineral, organic acid, licorice, jasmine residue, gypenoside, vitamin, corn straw and melatonin according to proportions to prepare a preform; (2) adding mixed fermentation liquor to the preform, uniformly mixing, standing for 10 h, and then performing ventilation drying at 60 DEG C to prepare the additive for improving the quality and yield of cashmere of a cashmere goat. Example 6

[0077] An additive for improving the quality and yield of cashmere of a cashmere goat is prepared from the following raw materials by weight: 25 parts of green forage, 14 parts of modified zinc-copper composite mineral, 13 parts of mixed fermentation liquor, 6 parts of organic acid, 4 parts of licorice, 4 parts of jasmine residue, 4 parts of gypenoside, 4 parts of vitamin, 3 parts of corn straw, and 0.5 parts of melatonin.

[0078] The mass ratio of Bacillus subtilis fermentation liquor and yeast fermentation liquor in the mixed fermentation liquor is 1:2; the effective viable count of the mixed fermentation liquor is 2.5 x 10 10 CFU / mL.

[0079] The modified zinc-copper composite mineral is a cystine-modified copper / zinc sulfide nanoparticle, the cystine-modified copper / zinc sulfide nanoparticle is prepared by mixing cystine, copper sulfate and zinc nitrate in an aqueous solution and then performing heat treatment, the heat treatment is performed under the condition that the reaction temperature is 130 DEG C, the reaction time is 10 h, and the mass ratio of cystine, copper sulfate and zinc nitrate is 1:1:3.

[0080] The green forage is a wild grass.

[0081] The organic acid is citric acid.

[0082] The vitamin is vitamin A, vitamin E.

[0083] A method for preparing an additive for improving the quality and yield of cashmere goat wool comprises the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) The mixed fermentation liquid is added to the preform, mixed evenly, and then allowed to stand for 10 hours, and then ventilated and dried at 60°C to obtain an additive for improving the quality and yield of cashmere goat wool. Example 7

[0084] An additive for improving the quality and yield of cashmere goat wool is prepared from the following raw materials in parts by weight: 25 parts of green fodder, 13 parts of modified zinc-copper composite minerals, 14 parts of mixed fermentation bacterial liquid, 6 parts of organic acid, 4 parts of liquorice, 5 parts of jasmine flower residue, 3 parts of gynostemma pentaphyllum polysaccharide, 3 parts of vitamins, 4 parts of corn straw, and 1.0 part of melatonin.

[0085] The mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth was 2:1; the effective viable cell count of the mixed fermentation broth was 3.5×10 10 CFU / mL.

[0086] The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution and then prepared by heat treatment. The heat treatment conditions are a reaction temperature of 130°C, a reaction time of 10 hours, and a mass ratio of cystine, copper sulfate and zinc nitrate of 1:1:3.

[0087] Green fodder is pasture grass.

[0088] The organic acid is malic acid.

[0089] Vitamins include vitamin A and vitamin E.

[0090] A method for preparing an additive for improving the quality and yield of cashmere goat wool comprises the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) The mixed fermentation liquid is added to the preform, mixed evenly, and then allowed to stand for 10 hours, and then ventilated and dried at 60°C to obtain an additive for improving the quality and yield of cashmere goat wool. Example 8

[0091] An additive for improving the quality and yield of cashmere goat wool is prepared from the following raw materials in parts by weight: 25 parts of green fodder, 14 parts of modified zinc-copper composite minerals, 13 parts of mixed fermentation bacterial liquid, 6 parts of organic acid, 4 parts of liquorice, 3 parts of jasmine flower residue, 3 parts of gynostemma pentaphyllum polysaccharide, 4 parts of vitamins, 4 parts of corn stalks, and 0.6 parts of melatonin.

[0092] The mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth was 1:2; the effective viable cell count of the mixed fermentation broth was 1.5×10 10 CFU / mL.

[0093] The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution and then prepared by heat treatment. The heat treatment conditions are a reaction temperature of 130°C, a reaction time of 10 hours, and a mass ratio of cystine, copper sulfate and zinc nitrate of 2:1:3.

[0094] Green fodder is vegetable leaves.

[0095] The organic acid is fumaric acid.

[0096] Vitamins include vitamin A and vitamin E.

[0097] A method for preparing an additive for improving the quality and yield of cashmere goat wool comprises the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) The mixed fermentation liquid is added to the preform, mixed evenly, and then allowed to stand for 10 hours, and then ventilated and dried at 60°C to obtain an additive for improving the quality and yield of cashmere goat wool. Example 9

[0098] An additive for improving the quality and yield of cashmere goat wool is prepared from the following raw materials in parts by weight: 28 parts of green fodder, 13 parts of modified zinc-copper composite minerals, 14 parts of mixed fermentation bacterial liquid, 7 parts of organic acid, 4 parts of liquorice, 4 parts of jasmine flower residue, 4 parts of gynostemma pentaphyllum polysaccharide, 3 parts of vitamins, 4 parts of corn stalks, and 1.5 parts of melatonin.

[0099] The mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth was 3:1; the effective viable cell count of the mixed fermentation broth was 5×10 10 CFU / mL.

[0100] The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution and then prepared by heat treatment. The heat treatment conditions are a reaction temperature of 130°C, a reaction time of 10 hours, and a mass ratio of cystine, copper sulfate and zinc nitrate of 2:1:3.

[0101] Green fodder is vegetable leaves.

[0102] The organic acid is citric acid.

[0103] The vitamin is vitamin A, vitamin E or vitamin D3.

[0104] A method for preparing an additive for improving the quality and yield of cashmere goat wool comprises the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) The mixed fermentation liquid is added to the preform, mixed evenly, and then allowed to stand for 12 hours, and then ventilated and dried at 80°C to obtain an additive for improving the quality and yield of cashmere goat wool. Example 10

[0105] An additive for improving the quality and yield of cashmere goat wool is prepared from the following raw materials in parts by weight: 28 parts of green fodder, 14 parts of modified zinc-copper composite minerals, 15 parts of mixed fermentation bacterial liquid, 6 parts of organic acid, 4 parts of liquorice, 5 parts of jasmine flower residue, 4 parts of gynostemma pentaphyllum polysaccharide, 6 parts of vitamins, 4 parts of corn stalks, and 1.5 parts of melatonin.

[0106] The mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth was 1:2; the effective viable cell count of the mixed fermentation broth was 4.5×10 10 CFU / mL.

[0107] The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution and then prepared by heat treatment. The heat treatment conditions are a reaction temperature of 130°C, a reaction time of 10 hours, and a mass ratio of cystine, copper sulfate and zinc nitrate of 2:2:5.

[0108] Green fodder is wild grass.

[0109] The organic acid is citric acid.

[0110] Vitamins include vitamin A and vitamin E.

[0111] A method for preparing an additive for improving the quality and yield of cashmere goat wool comprises the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) The mixed fermentation liquid is added to the preform, mixed evenly, and then allowed to stand for 12 hours, and then ventilated and dried at 80°C to obtain an additive for improving the quality and yield of cashmere goat wool. Example 11

[0112] An additive for improving the quality and yield of cashmere goat wool is prepared from the following raw materials in parts by weight: 30 parts of green fodder, 15 parts of modified zinc-copper composite minerals, 17 parts of mixed fermentation bacterial liquid, 8 parts of organic acid, 4 parts of liquorice, 5 parts of jasmine flower residue, 4 parts of gynostemma pentaphyllum polysaccharide, 8 parts of vitamins, 5 parts of corn stalks, and 1.5 parts of melatonin.

[0113] The mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth was 3:1; the effective viable cell count of the mixed fermentation broth was 5×10 10 CFU / mL.

[0114] The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution and then prepared by heat treatment. The heat treatment conditions are a reaction temperature of 130°C, a reaction time of 10 hours, and a mass ratio of cystine, copper sulfate and zinc nitrate of 3:1:5.

[0115] Green fodder is wild grass.

[0116] The organic acid is fumaric acid.

[0117] The vitamin is vitamin A, vitamin E or vitamin D3.

[0118] A method for preparing an additive for improving the quality and yield of cashmere goat wool comprises the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) The mixed fermentation liquid is added to the preform, mixed evenly, and then allowed to stand for 12 hours, and then ventilated and dried at 80°C to obtain an additive for improving the quality and yield of cashmere goat wool. Example 12

[0119] An additive for improving the quality and yield of cashmere goat wool is prepared from the following raw materials in parts by weight: 30 parts of green fodder, 15 parts of modified zinc-copper composite minerals, 18 parts of mixed fermentation bacterial liquid, 8 parts of organic acid, 5 parts of liquorice, 5 parts of jasmine flower residue, 4 parts of gynostemma pentaphyllum polysaccharide, 8 parts of vitamins, 5 parts of corn stalks, and 1.5 parts of melatonin.

[0120] The mass ratio of Bacillus subtilis fermentation broth to yeast fermentation broth in the mixed fermentation broth was 3:2; the effective viable cell count of the mixed fermentation broth was 5×10 10 CFU / mL.

[0121] The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution and then prepared by heat treatment. The heat treatment conditions are a reaction temperature of 130°C, a reaction time of 10 hours, and a mass ratio of cystine, copper sulfate and zinc nitrate of 3:2:5.

[0122] Green fodder is wild grass.

[0123] The organic acid is citric acid.

[0124] Vitamins include vitamin A and vitamin E.

[0125] A method for preparing an additive for improving the quality and yield of cashmere goat wool comprises the following steps: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) The mixed fermentation liquid is added to the preform, mixed evenly, and then allowed to stand for 12 hours, and then ventilated and dried at 80°C to obtain an additive for improving the quality and yield of cashmere goat wool.

[0126] Comparative Example 1 A cashmere goat feed additive is prepared from the following raw materials in parts by weight: 25 parts of green fodder and 15 parts of mixed fermentation liquid. The mixed fermentation liquid is a Bacillus subtilis fermentation liquid and a yeast fermentation liquid in a volume ratio of 1:2, and the effective viable cell count of the Bacillus subtilis fermentation liquid and the yeast fermentation liquid is 3.2×10 10 CFU / mL.

[0127] The effective viable count of lactic acid bacteria was 1.5×10 10 CFU / mL.

[0128] The preparation method is the same as that of Example 1, and the product is dried under ventilation at 60° C. to a moisture content of 4.5% to obtain a cashmere goat feed additive.

[0129] Comparative Example 2 A cashmere goat feed additive is prepared from the following raw materials in parts by weight: 20 parts of lactic acid fermentation bacterial liquid, 12 parts of modified zinc-copper composite minerals, and 15 parts of mixed fermentation bacterial liquid.

[0130] The mixed fermentation broth was composed of Bacillus subtilis fermentation broth and yeast fermentation broth in a volume ratio of 1:2. The effective viable cell counts of both Bacillus subtilis fermentation broth and yeast fermentation broth were 3.2×10 10 CFU / mL.

[0131] The effective viable bacteria count of lactic acid fermentation solution was 2.5×10 10 CFU / mL.

[0132] The preparation method is the same as that of Example 1, and the product is dried under ventilation at 60° C. to a moisture content of 4.5% to obtain a cashmere goat feed additive.

[0133] Comparative Example 3 A cashmere goat feed additive is prepared from the following raw materials in parts by weight: 20 parts of green fodder, 20 parts of lactic acid fermentation bacteria liquid, and 12 parts of modified zinc-copper composite minerals.

[0134] The effective viable bacteria count of lactic acid fermentation solution was 2.5×10 10 CFU / mL.

[0135] The preparation method is the same as that of Example 1, and the product is dried under ventilation at 60° C. to a moisture content of 4.5% to obtain a cashmere goat feed additive.

[0136] Comparative Example 4 A cashmere goat feed additive is prepared from the following raw materials in parts by weight: 20 parts of green fodder, 20 parts of mixed fermentation bacterial liquid, and 12 parts of zinc-copper composite minerals.

[0137] The zinc-copper composite mineral is copper / zinc nanoparticles. The mixed fermentation broth is a 1:2 volume ratio of Bacillus subtilis fermentation broth and yeast fermentation broth. The effective viable cell count of both Bacillus subtilis fermentation broth and yeast fermentation broth is 3.2×10 10 CFU / mL.

[0138] The preparation method is the same as that of Example 1, and the product is dried under ventilation at 60° C. to a moisture content of 4.5% to obtain a cashmere goat feed additive.

[0139] 80 cashmere goats of the same origin, weighing approximately 16 kg, and 6 months old, were selected and raised under the same feeding conditions and randomly divided into 4 groups, 20 in each group. No significant differences were found between the groups. One experimental group was fed with the feed additive prepared in Examples 1-4 + ordinary feed; three control groups were fed with the feed additive prepared in Comparative Examples 1-4 + ordinary feed, wherein the amount of feed additives in Examples 1-4 and Comparative Examples 1-4 was 5% of the total amount of ordinary feed; the number of daily feedings, feeding amounts, and feeding times were all the same, and the cashmere goats had free access to food and water. The experimental period was 28 days, and the recorded results are shown in Table 1.

[0140] As shown in Table 1, the feed additive prepared in Example 1 increased the average daily feed intake and average daily weight gain of cashmere goats, improving feed conversion rate. This effect was achieved through synergistic effects. The modified zinc-copper composite mineral added was cystine-modified copper / zinc sulfide nanoparticles. Cystine-modified copper / zinc sulfide nanoparticles use cystine as a sulfur source and surface modifier, are mixed with copper sulfate and zinc nitrate in an aqueous solution, and then heat-treated to produce the product. Minerals such as zinc, copper, and sulfur are essential elements for cashmere goat hair growth. Zinc is involved in hair follicle development and fiber growth. Zinc deficiency can lead to hair follicle degeneration and reduced hair production. Copper affects wool / cashmere pigmentation and fiber strength, and synergistically with zinc can improve production performance. Sulfur is a core component of keratin synthesis (keratin accounts for 90% of cashmere fiber), and cystine and cysteine ​​are sulfur-rich amino acids in keratin. Supplementing the diet with the sulfur-containing substance cystine significantly increases cashmere yield and sulfur content. Modifying the copper / zinc sulfide nanoparticles with cystine imparts antioxidant properties and enhances their stability. The high surface area of ​​nanoparticles may increase the bioavailability of minerals and promote absorption by hair follicles. Cystine, as a sulfur source, can directly provide the cysteine ​​required for keratin synthesis. Supplementing with sulfur-containing compounds can increase the cysteine ​​and sulfur content in cashmere fibers, promoting cashmere growth.

[0141] At the same time, Bacillus subtilis fermentation broth and yeast fermentation broth are added to the mixed fermentation broth. Bacillus subtilis can secrete protease, amylase and lipase to decompose complex carbohydrates and improve the utilization rate of feed nutrients. Bacillus and yeast quickly create an anaerobic environment for lactic acid bacteria. At the same time, they have the ability to secrete various digestive enzymes, adjust the pH value of the microecological balance of the rumen fermentation system of cashmere goats, increase propionic acid production, reduce methane production and lactic acid accumulation, increase the number of rumen bacteria and their activity in fiber degradation, and improve feed digestibility. The feed additive prepared in Example 1 effectively increases the length, thickness and length of cashmere goat hair, increases cashmere production and improves hair quality.

[0142] The foregoing description is merely an exemplary embodiment of the present invention, and the scope of protection of the present invention is not limited thereto. Any changes or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be based on the scope of protection of the claims.

Claims

1. An additive for improving the quality and yield of cashmere goat wool, characterized in that: The invention is prepared from the following raw materials in parts by weight: 20-30 parts of green fodder, 12-15 parts of modified zinc-copper composite minerals, 12-18 parts of mixed fermentation bacterial liquid, 5-8 parts of organic acid, 3-5 parts of licorice, 3-5 parts of jasmine flower residue, 3-4 parts of gynostemma pentaphyllum polysaccharide, 2-8 parts of vitamins, 3-5 parts of corn stalks, and 0.5-1.5 parts of melatonin; the mixed fermentation bacterial liquid is a mixture of Bacillus subtilis fermentation liquid and yeast fermentation liquid.

2. The additive for improving the quality and yield of cashmere goat wool according to claim 1, characterized in that: The mass ratio of the Bacillus subtilis fermentation liquid to the yeast fermentation liquid in the mixed fermentation liquid is 1-3:1-2.

3. The additive for improving the quality and yield of cashmere goat wool according to claim 1, characterized in that: The effective viable bacteria count of the mixed fermentation broth was 1.5×10 10 -5×10 10 CFU / mL.

4. The additive for improving the quality and yield of cashmere goat wool according to claim 1, characterized in that: The modified zinc-copper composite mineral is cystine-modified copper / zinc sulfide nanoparticles. The cystine-modified copper / zinc sulfide nanoparticles are prepared by mixing cystine as a sulfur source and surface modifier with copper sulfate and zinc nitrate in an aqueous solution and then subjecting the mixture to heat treatment. The mass ratio of cystine, copper sulfate and zinc nitrate is 1-3:1-2:3-5.

5. The additive for improving the quality and yield of cashmere goat wool according to claim 1, characterized in that: The green fodder is one or more of vegetable leaves, weeds, pasture grass or tree leaves.

6. The additive for improving the quality and yield of cashmere goat wool according to claim 1, characterized in that: The organic acid is one of citric acid, malic acid and fumaric acid.

7. The additive for improving the quality and yield of cashmere goat wool according to claim 1, characterized in that: The vitamin is one or more of vitamin A, vitamin E or vitamin D3.

8. The method for preparing the additive for improving the quality and yield of cashmere goat wool according to any one of claims 1 to 7, characterized in that: The following steps are involved: (1) Green fodder, modified zinc-copper composite minerals, organic acid, licorice, jasmine flower residue, gynostemma pentaphyllum polysaccharide, vitamins, corn straw and melatonin are weighed and mixed in proportion to prepare a preform; (2) Add the mixed fermentation liquid to the preform, mix evenly, let it stand for 8-12 hours, and then ventilate and dry at 50-80°C to obtain an additive for improving the quality and yield of cashmere goat wool.

9. Use of the additive for improving the quality and yield of cashmere goat wool according to claim 1 in preparing cashmere goat breeding feed.

10. Use of the additive for improving the quality and yield of cashmere goat wool according to claim 9 in preparing cashmere goat breeding feed, characterized in that: The mixed breeding feed is a feed for improving the quality and yield of cashmere goat wool.

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