Veterinary traditional Chinese medicine powder for treating trauma
By preparing a veterinary Chinese medicine powder containing calcined gypsum, calcined calamine, rhubarb, dragon's blood, borneol, frankincense and myrrh, the problems of existing veterinary trauma drug preparations such as single efficacy, poor adhesion and high toxicity are solved, and efficient treatment of animal trauma and insect prevention effects are achieved.
Patent Information
- Application Number
- CN202510900932.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-01
- Publication Date
- 2025-10-10
AI Technical Summary
Existing veterinary trauma medicine preparations have a single efficacy, poor adhesion, contain toxic drugs and cannot be used together with iodine preparations. They cannot effectively prevent insects and are especially not suitable for animals with frequent activities.
A veterinary Chinese medicine powder is used, which is composed of calcined gypsum, calcined calamine, rhubarb, dragon's blood, borneol, frankincense and myrrh. After powdering, it is passed through a 120-mesh sieve, mixed and sterilized to make a fine powder. The powder has astringent, anti-infection and anti-insect effects and is suitable for use in combination with iodine preparations.
It has achieved significant therapeutic effects on animal injuries. The powder has strong adhesion, can effectively prevent insects, does not contain toxic drugs, has a fast healing speed, and is suitable for animals with frequent activities.
Smart Images
Figure CN120754185A_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of veterinary Chinese medicine, and specifically relates to a veterinary Chinese medicine powder for treating trauma, which is mainly aimed at animals with large wounds that cannot undergo frequent debridement operations, such as wild animals or stray animals. Background Art
[0002] Animal trauma is common. Scratches, bites, lacerations, and large skin loss are not only common in pet dogs and cats, but are even more common in commercial and wild animals. Trauma in the latter species often presents with large wounds, susceptibility to insect infestation, and inability to frequently cleanse. Therefore, when treating these injuries, it is important to consider not only anti-infective properties but also insect repellent properties and strong adhesion.
[0003] Because of their small particle size, powders have stronger adhesion than ointments. Existing veterinary trauma powders are primarily based on Yunnan Baiyao, a human medicine whose primary efficacy is to promote blood circulation and stop bleeding, resulting in a relatively simple effect. Existing commercial veterinary powders, such as Anti-corrosion and Muscle-Stimulating Powder, use classic pharmacopoeial formulas to promote astringency, promote tissue regeneration, and combat infection. However, they contain highly toxic drugs such as calomel and should not be used with commonly used iodine preparations. They are also expensive, and the powder sieved through a 60-mesh sieve is coarse, leaving a poor skin feel after use, requiring manual secondary sieving through a 120-mesh sieve before use.
[0004] In view of this, the present invention is proposed. Summary of the Invention
[0005] The present invention aims to provide a veterinary traditional Chinese medicine powder for treating trauma, which has multiple functions such as astringency, anti-infection and insect repellency. After being pulverized and sieved through 120 meshes, the powder has fine texture and good skin feel and can be used together with iodine preparations.
[0006] In order to achieve the above object, the technical solution adopted by the present invention is as follows: In a first aspect, the present invention provides a veterinary Chinese medicine composition comprising the following components: 25-50 parts by weight of calcined gypsum, 45-80 parts by weight of calcined calamine, 20-50 parts by weight of rhubarb, 5-20 parts by weight of dragon's blood, 2.5-5 parts by weight of borneol, 6-20 parts by weight of frankincense, and 6-20 parts by weight of myrrh.
[0007] As a specific embodiment of the present invention, the veterinary Chinese medicine composition is composed of the following medicinal ingredients in parts by weight: 25 parts by weight of calcined gypsum, 70 parts by weight of calcined calamine, 20 parts by weight of rhubarb, 5 parts by weight of dragon's blood, 2.5 parts by weight of borneol, 6 parts by weight of frankincense, and 6 parts by weight of myrrh.
[0008] In a second aspect, the present invention provides a method for preparing the veterinary Chinese medicine composition, comprising the following steps: powdering the various medicinal ingredients, mixing, and sterilizing to obtain the composition.
[0009] In a third aspect, the present invention provides a veterinary Chinese medicine preparation, comprising the veterinary Chinese medicine composition.
[0010] The dosage form of the traditional Chinese medicine preparation is powder, paste and spray.
[0011] The particle size of the powder is less than 160 mesh.
[0012] In a fourth aspect, the present invention provides the use of the veterinary Chinese medicine composition and the veterinary Chinese medicine preparation in the preparation of medicines for animal skin ulcers, inflammation and trauma.
[0013] The animal injuries include scratches, bites, lacerations and large-area skin loss.
[0014] The animals are mammals, such as dogs, cats, horses, sheep, monkeys, etc.
[0015] The veterinary Chinese medicine preparation is used in combination with an iodine preparation, and the medicine is changed once every 5-7 days.
[0016] In a fifth aspect, the present invention provides a combined preparation comprising a Chinese medicine powder and an iodine preparation; the Chinese medicine powder and the iodine preparation are packaged separately.
[0017] In the composition provided by the present invention, calcined gypsum has the effects of astringing dampness, stopping bleeding and promoting tissue regeneration, and is often used externally to treat ulcers that do not heal. Calcined calamine, a main component of which is zinc oxide, has the effects of promoting tissue regeneration and healing ulcers, astringing dampness and detoxifying, and can be used together with calcined gypsum to improve its efficacy. External use of rhubarb can purge heat and detoxify, cool blood and reduce swelling, and treat toxic carbuncles, boils, and furuncles. It can also be used externally to treat burns and scalds, either alone or in combination with other drugs. Dragon's blood lees is the resin of the sword-leaved Dracaena tree of the Liliaceae family, and has the effects of promoting blood circulation and dispersing blood stasis, relieving pain and stopping bleeding, and healing ulcers and promoting tissue regeneration. Borneol can invigorate the mind, clear away heat and relieve pain, and can be used externally to prevent corrosion and promote tissue regeneration, and treat ulcers that do not heal. Because its fragrance contains volatile components, it can also mask other odors, thus having a certain insect repellent effect. Frankincense and myrrh have similar functions: they both promote blood circulation, relieve pain, reduce swelling, promote tissue regeneration, and treat persistent sores and ulcers. They are essential remedies for traumatic injuries. However, frankincense is more focused on promoting qi and relieving pain, while myrrh is more focused on dispersing blood and removing stasis. Therefore, while this herb reduces swelling and detoxifies, it also possesses astringent properties, promotes tissue regeneration, and protects against insects.
[0018] The formula of the composition provided by the present invention is as follows: This prescription tends to be astringent as the main ingredient, with anti-infection as the auxiliary ingredient, and also takes into account the effects of tissue regeneration and insect repellence. Therefore, in terms of compatibility, calcined gypsum and calamine are the main ingredients, which are astringent and dampness-reducing, while rhubarb is the auxiliary ingredient, which is antibacterial and anti-infective. A small amount of dragon's blood, frankincense and myrrh are added to promote tissue regeneration, activate blood circulation and remove blood stasis. Finally, a small amount of borneol is added to prevent insects and relieve pain.
[0019] Compared with the prior art, the present invention has the following beneficial effects: The present invention discloses a traditional Chinese medicine powder for treating animal wounds, which has anti-infection, astringency, myogenic, and insect repellent effects. The powder is applied directly to the affected area after debridement. During animal activity, the powder is unlikely to completely fall off, and fine powdery particles form a thin layer on the wound surface, isolating the damaged skin from the outside world while still exerting its medicinal effects. Clinical trials have demonstrated significant therapeutic effects. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 These are comparison photos of the wound surface of the right forelimb wrist joint of an argali sheep (female, 1 year old) before and after treatment.
[0021] Figure 2 These are photos comparing the wound surface on the nasal concha of a 9-year-old male sheep before and after treatment.
[0022] Figure 3 These are photos comparing the bite wounds on the two hind limbs of a zebra (female, 7 years old) before and after treatment.
[0023] Figure 4 Comparison photos of the bite wound of a ring-tailed lemur (male, 7 years old) before and after treatment.
[0024] Figure 5 Comparison photos of the bite wound of a ring-tailed lemur (female, 6 years old) before and after treatment.
[0025] Figure 6 This is a mouse skin damage repair experiment. DETAILED DESCRIPTION
[0026] The present invention will be further described below with reference to specific examples, but the present invention is not limited to the following examples.
[0027] Unless otherwise specified, the experimental methods used in the following examples are conventional methods.
[0028] Unless otherwise specified, the reagents, materials, instruments, etc. used in the following examples can be obtained from commercial sources.
[0029] Example 1, Chinese medicine powder A traditional Chinese medicine powder for treating trauma in animals is prepared from the following raw materials in a weight ratio: 25g of calcined gypsum, 70g of calcined calamine, 20g of rhubarb, 5g of dragon's blood, 2.5g of borneol, 6g of frankincense, and 6g of myrrh (the weight of the above medicinal materials is the weight after they are individually powdered and sieved through a 120-mesh sieve). The powder is mixed, sieved through a 160-mesh sieve, sterilized for 30 minutes, and bottled to obtain a finished product.
[0030] Example 2, Chinese medicine powder A traditional Chinese medicine powder for veterinary wound treatment is prepared from the following ingredients by weight: 50g calcined gypsum, 45g calcined calamine, 50g rhubarb, 20g dragon's blood, 5g borneol, 20g frankincense, and 20g myrrh. (The weight of each of these herbs is calculated after individual powdering and sieving through a 120-mesh sieve). The powder is then mixed, passed through a 160-mesh sieve, sterilized for 30 minutes, and bottled to yield the finished product.
[0031] Application Example 1: Animal Therapy Experiment Experimental method: After the affected area is debrided, the powder prepared in Example 1 is directly sprinkled on the affected area. If there is no obvious exudation from the affected area and the powder adheres well, the dressing can be changed once every 5-7 days.
[0032] Case 1: A female argali sheep, 1 year old, had very poor vision due to an eye disease, which resulted in a bruise on the wrist joint of the right forelimb during activities, resulting in a large area of epidermis loss, bleeding, infection, and obvious swelling of the joint. Figure 1 (a) Anesthesia and debridement. Apply the above prescription to the affected area and bandage it. Debride the wound once every 2 weeks. After two debridements, there is no infection on the wound surface, slight swelling of the joint, no obvious flies and insects around, and the wound is 50% healed. Figure 1 (b) Continue to use the above prescription and apply it to the affected area after the third debridement without bandaging. The affected area is basically healed after 1 month. After the hair grows, there is no obvious abnormality.
[0033] Case 2: A 9-year-old male sheep frequently hit the iron pillars of the animal house due to bad mood, resulting in a large area of skin loss at the nasal concha. The exposed nasal concha was about 5 cm in diameter, and the surrounding residual skin was severely necrotic. Figure 2 (a) Loss of appetite. After anesthesia, the wound was cleaned and the surrounding necrotic skin was repaired. Due to the large amount of skin loss, only part of the suture could be done. Then the above prescription was applied to the affected area without bandaging. Figure 2 (b) Only one debridement was performed. After one month, the wound healed well with only a scar tissue of about 4 cm in length. There was no infection or insect infestation during this period. Figure 2 (c).
[0034] Case 3: Zebra, female, 7 years old, with large-area infection, pus discharge, and lameness due to bite wounds on both hind legs. Figure 3 (a) After anesthesia and debridement, apply the above prescription to the affected area, such as Figure 3 (b) In less than a month, the wounds on the two hind legs were basically healed. Figure 3 (c). After the hind legs were debrided under anesthesia, the zebra began to bite its left forelimb. Figure 3 (d) After debridement without anesthesia, apply the above prescription to the affected area, such as Figure 3 (e) Debride and apply medicine once a week, and check again after 1 month, and the wound is 50% healed. Figure 3(f), and then again self-mutilation bite causes wound expansion, using the same treatment, increase personnel behavior training, review after 2 months, basically healed.
[0035] Case 4: Ring-tailed lemur, male, 7 years old, bitten during estrus, such as Figure 4 (a), loss of appetite, limited activity, debridement after anesthesia, suture after skin trimming, using the above prescription on the affected area, such as Figure 4 (b), 2 days later, the appetite returned, such as Figure 4 (c); such as Figure 4 (d), discharged after half a month and returned to the group feeding.
[0036] Case 5: Ring-tailed lemur, female, 6 years old, bitten during postpartum lactation, such as Figure 5 (a), depression, limited activity, abnormal lactation of the infant, debridement after anesthesia, suture after large wound trimming, open after small wound debridement, using the above prescription on the affected area, such as Figure 5 (b), 3 days later, the appetite returned, normal lactation, clean wound scab, healing trend, such as Figure 5 (c), 9 days later, discharged back to the group, the wound healed, such as Figure 5 (d).
[0037] Application Example 2, mouse skin damage repair experiment Experimental method: small white mice weighing about 35g were randomly divided into 4 groups, labeled A, B, C and D, 5 in each group. Anesthetized with Xylazine and Domitor intramuscularly, Xylazine dose 40 μg / g, Domitor 0.01 μg / g, after anesthesia, the back hair was shaved with pet electric scissors, the back floating hair was wiped off with 75% alcohol, and a circular mark with a diameter of 0.5 cm was drawn on both sides of the back with a medical skin marker, such as Figure 6 (a). After disinfection according to the alcohol-iodine alcohol-iodine removal process, the epidermis was cut out with sterile surgical scissors according to the circular mark outline, such as Figure 6 (b). After the mice completely woke up, they were separated into cages, one in each cage, to prevent biting.
[0038] The drug powder used in this experiment is the traditional Chinese medicine powder prepared in Example 1.
[0039] Group A is the Yunnan White Powder group. After the wound is washed clean with 0.9% Nacl, the surface moisture is absorbed with sterile gauze, Yunnan White Powder is applied to the left wound, and the above-mentioned drug powder is applied to the right wound. Group B is the Antiseptic Shengji Powder group. After the wound is washed clean with 0.9% Nacl, the surface moisture is absorbed with sterile gauze, Antiseptic Shengji Powder is applied to the left wound, and the above-mentioned drug powder is applied to the right wound. Group C received hypochlorous acid skin spray, which had a chlorine concentration of 300 ppm ± 50. The wound surface was rinsed with 0.9% NaCl, and the surface moisture was dried with sterile gauze. Hypochlorous acid was sprayed on the left wound surface, and the above-mentioned powder was applied externally on the right wound surface. Group D served as the blank control group. The wound was rinsed with 0.9% NaCl and the surface moisture was dried with sterile gauze. No drugs were used on the left wound, and the above-mentioned powder was applied to the right wound.
[0040] The above four groups were treated with medication once a week, and the wound healing status was recorded by visual observation, measurement with a ruler, and the average value was taken.
[0041] Table 1 Wound healing measurement data
[0042] The results show that: (1) Compared with Yunnan Baiyao, the above-mentioned powder has similar adhesion, better astringency and faster healing speed. At the same time, according to the records of previous animal trauma treatment, it can be seen that the use of Yunnan Baiyao powder to treat animal trauma is mainly to promote blood circulation and stop bleeding, and the wound healing depends more on the animal's own skin healing ability.
[0043] (2) Compared with the antiseptic and prospering powder, the above-mentioned powder has stronger adhesion, better astringency and faster healing speed. In addition, the antiseptic and prospering powder is highly toxic and cannot be used together with iodine preparations. It is also expensive.
[0044] (3) Compared with hypochlorous acid skin spray, the above-mentioned powder has stronger adhesion, is licked more slowly by the skin itself, and heals faster. Since this experiment was a non-infectious wound, the blank group did not have infection and non-healing, but the healing speed was slower.
[0045] The treatment results of the above cases show that the traditional Chinese medicine powder provided by the present invention has multiple functions such as anti-infection, astringency, tissue regeneration, and insect repellency, and does not contain highly toxic drugs such as calomel, and can be used together with commonly used iodine preparations, thereby solving the problems existing in the use of existing veterinary trauma drug preparations, such as single efficacy, poor adhesion, high toxicity, and inability to be used in combination with iodine preparations.
[0046] Although the present invention has been described in detail above using general descriptions and specific embodiments, it will be apparent to those skilled in the art that modifications and improvements may be made based on the present invention. Therefore, such modifications and improvements, which do not depart from the spirit of the present invention, are intended to be within the scope of protection claimed herein.
Claims
1. A veterinary Chinese medicine composition comprising the following components: 25-50 parts by weight of calcined gypsum, 45-80 parts by weight of calcined calamine, 20-50 parts by weight of rhubarb, 5-20 parts by weight of dragon's blood, 2.5-5 parts by weight of borneol, 6-20 parts by weight of frankincense, and 6-20 parts by weight of myrrh.
2. The veterinary Chinese medicine composition according to claim 1, characterized in that The invention is composed of the following medicinal ingredients in parts by weight: 25 parts by weight of calcined gypsum, 70 parts by weight of calcined calamine, 20 parts by weight of rhubarb, 5 parts by weight of dragon's blood, 2.5 parts by weight of borneol, 6 parts by weight of frankincense and 6 parts by weight of myrrh.
3. The preparation method of the veterinary Chinese medicine composition according to claim 1 or 2, comprising the steps of: powdering the various medicinal ingredients, mixing, and sterilizing to obtain the composition.
4. A veterinary Chinese medicine preparation comprising the veterinary Chinese medicine composition according to claim 1 or 2.
5. The veterinary Chinese medicine preparation according to claim 4, characterized in that: The dosage form of the traditional Chinese medicine preparation is powder, paste and spray.
6. The veterinary Chinese medicine preparation according to claim 4, characterized in that: The particle size of the powder is less than 160 mesh.
7. Use of the veterinary Chinese medicine composition according to claim 1 or 2, or the veterinary Chinese medicine preparation according to claim 4 or 5, in the preparation of medicines for treating animal skin ulcers, inflammation and trauma.
8. The use according to claim 7, characterized in that The animal injuries include scratches, bites, lacerations and large-area skin loss.
9. The use according to claim 7, characterized in that The animal is a mammal.
10. A combined preparation comprising a traditional Chinese medicine powder and an iodine preparation; the traditional Chinese medicine powder and the iodine preparation are packaged separately.