Adjustable double-cavity insulin injection pen

Abstract

The invention discloses an adjustable double-cavity insulin injection pen which comprises an L-shaped plate, an injection cavity, a piston, a speed adjusting motor, a control panel, a battery and a screw. Different drugs such as insulin and GLP1-RA are loaded in the injection cavities symmetrically formed in the L-shaped plate, the rotating speed of the speed adjusting motors on the two sides can be independently adjusted through the control panel, the push injection speed of the piston is controlled through the driving screw, the doses of different drug components can be accurately adjusted, the individual difference requirements of patients are met, and the application range is wide. The problem that the dosage of fixed-proportion mixed injection cannot be flexibly adjusted is solved; a mixing tee joint is arranged, a liquid inlet of the Y-shaped mixing tee joint is correspondingly connected with liquid outlets of the two injection cavities, a micro paddle disc is arranged at the crossed position of the mixing tee joint, rotation resistance is reduced through a micro bearing, and when the injection cavities on the two sides inject medicine into the mixing tee joint, the micro paddle disc is pushed by liquid to rotate; two kinds of liquid medicine entering the mitigation tee joint are stirred, uniform mixing is guaranteed, and the medicine absorption efficiency is improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of diabetes treatment devices, in particular to an adjustable double-cavity insulin injection pen. BACKGROUND

[0002] In the field of treatment of diabetes and related endocrine and metabolic diseases, insulin injection and GLP1-RA injection are common treatment methods. In the actual patient treatment scene, there are a large number of insulin injection and GLP1-RA injection treatment conditions. Moreover, in insulin injection treatment, multiple insulins are injected multiple times in the same patient, and two insulins are also commonly used for combined treatment. For example, long-acting insulin and fast-acting insulin often need to be injected at the same time, and long-acting insulin and GLP1-RA injection also need to be injected at the same time.

[0003] By 2025, some fixed ratio mixed injection liquids for the above-mentioned combined treatment will appear on the market, which can be injected by one insulin pen, such as insulin aspart and insulin lispro injection, and these products can complete the injection treatment of two different components at one time, which provides a certain degree of convenience for patients.

[0004] However, such fixed ratio mixed injection liquids have obvious deficiencies. The contents of the two components are fixed in the same injection, which belongs to a fixed ratio mixture (FRC). Since the conditions, physical conditions and responses to drugs of different patients are different, the fixed ratio of the drug combination cannot meet the demand for precise adjustment of blood glucose treatment, and the amount of each drug component cannot be flexibly adjusted according to individual differences of patients.

[0005] The existing injection equipment cannot solve this problem, so there is an urgent need to design a new type of equipment to meet the demand for flexible adjustment of the dosage of insulin and GLP1-RA and other drugs in clinical treatment, realize more precise blood glucose control, and improve the treatment effect of diabetes and related diseases. SUMMARY

[0006] In order to solve the drawbacks of the prior art, the present application is realized by the following technical scheme; An adjustable double-cavity insulin injection pen, comprising: an L-shaped plate; The L-shaped plate is symmetrically provided with injection cavities at the front part, and limit grooves are symmetrically formed in the middle part of the L-shaped plate; The L-shaped plate is integrally provided with a mounting box at the lower part of the rear end, integrally provided with a battery box at the upper part of the rear end, and integrally provided with a control panel at the upper end of the front part; A piston is movably mounted in the injection cavity, and a mixing tee is sealingly connected to the front end of the injection cavity; The speed regulating motor is symmetrically arranged inside the mounting box; the output shaft of the motor is rotationally connected with the L-shaped plate; the output shaft of the motor is key-connected with the gear disc at the front end; The screw rod is rotationally mounted inside the limiting groove; the screw rod is integrally provided with a gear disc at the rear end, which is meshingly connected with the gear disc; Further, the mixing tee is Y-shaped, two liquid inlet ports of the mixing tee are symmetrically inserted into the outlet ports of the injection cavities; the liquid outlet port of the mixing tee is movably connected with the disposable sterile injection needle; The micro paddle is rotationally mounted inside the intersection position of the mixing tee; Further, the diameter of the micro paddle is matched with the inner diameter of the intersection position of the mixing tee, and the blades of the micro paddle are spirally distributed; the two ends of the micro paddle are symmetrically provided with micro bearings rotationally connected with the inner wall of the mixing tee, so that the friction of the micro paddle is reduced through the micro bearings; Further, the control panel comprises a display screen, control buttons and a microprocessor, the microprocessor is electrically connected with the display screen, control buttons and speed regulating motor respectively; the rotation speed of the speed regulating motor is input through the control panel, so that the rotation speed control of the speed regulating motor is realized; Further, the battery is clampedly mounted in the clamping groove inside the battery box, so that the control panel and the speed regulating motor are provided with power supply guarantee through the battery; Further, a straight rod is integrally arranged on the rear end rod body of the piston, the lower end of the straight rod is slidingly mounted in the limiting groove, and a screw hole is formed in the straight rod and is threadedly connected with the screw rod in the limiting groove; the rotation of the screw rod is driven by the speed regulating motor, the sliding of the straight rod in the limiting groove is controlled, and then the bolus injection of the insulin in the injection cavity is realized.

[0007] The beneficial effects of the present application are: The present application sets up the deficiency of the prior art adjustable double-cavity insulin injection pen, discloses an adjustable double-cavity insulin injection pen, which comprises an L-shaped plate, injection cavities, a piston, a speed regulating motor, a control panel, a battery and a screw rod; the injection cavities symmetrically arranged on the L-shaped plate are respectively filled with different drugs, such as insulin and GLP1-RA, and the rotation speeds of the speed regulating motors on both sides can be independently adjusted through the control panel, the screw rod is driven to control the bolus injection speed of the piston, the dose of different drug components can be accurately adjusted, the individual difference requirements of patients are met, and the problem that the fixed proportion of mixed injection liquid cannot be flexibly adjusted is solved; Further, the mixing tee is Y-shaped, two liquid inlet ports of the mixing tee are symmetrically inserted into the outlet ports of the injection cavities; the liquid outlet port of the mixing tee is movably connected with the disposable sterile injection needle; BRIEF DESCRIPTION OF DRAWINGS

[0008] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required to be used for the description of the embodiments will be briefly introduced.

[0009] Figure 1 It is a schematic diagram of the overall structure of an adjustable double-chamber insulin injection pen. Figure 2 It is a schematic diagram of the sectional structure of an adjustable double-chamber insulin injection pen. Figure 3 It is a schematic diagram of the partial sectional structure of an adjustable double-chamber insulin injection pen. Figure 4 It is a schematic diagram of the connection structure of a screw rod and a piston and a speed regulating motor of an adjustable double-chamber insulin injection pen.

[0010] In the drawings, the component list represented by each reference numeral is as follows: L-shaped plate, 101-limiting groove, 102-mounting box, 103-battery box, 1031-battery, 104-control panel, 2-injection chamber, 201-piston, 211-straight rod, 3-mixing tee, 301-micro paddle, 4-speed regulating motor, 401-tooth disc, 5-screw rod, 5011-tooth disc one. DETAILED DESCRIPTION

[0011] In order to solve the problems existing in the prior art adjustable double-chamber insulin injection pen, the present application discloses an adjustable double-chamber insulin injection pen, comprising: an L-shaped plate; The L-shaped plate 1 is symmetrically provided with an injection chamber 2 at the front part, and a limiting groove 101 is symmetrically provided in the middle part of the L-shaped plate 1; The L-shaped plate 1 is integrally provided with a mounting box 102 at the lower part of the rear end, integrally provided with a battery 1031 box 103 at the upper part of the rear end, and integrally provided with a control panel 104 at the upper end of the front part; The injection chamber 2 is movably mounted with a piston 201 inside, and a mixing tee 3 is sealingly connected to the front end of the injection chamber 2; The mounting box 102 is symmetrically provided with a speed regulating motor 4 inside; the output shaft of the motor is rotatably connected with the L-shaped plate 1; the output shaft of the motor is key-connected with a tooth disc 401 at the front end; The limiting groove 101 is rotatably mounted with a screw rod 5 inside; the screw rod 5 is integrally provided with a tooth disc one 5011 at the rear end, which is meshingly connected with the tooth disc 401 The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application; obviously, the described embodiments are only a part of the embodiments of the present application, not all the embodiments.

[0012] Embodiment 1 In the field of diabetes and related endocrine and metabolic disease treatment, with the change of disease spectrum and the expansion of patient population, the demand for personalized treatment is increasingly prominent. According to the International Diabetes Federation (IDF) 2024 report, the global number of diabetes patients has exceeded 570 million, of which 140 million are in China, and the trend is becoming younger. Clinical research shows that more than 60% of patients with moderate to severe diabetes need to use insulin combined with GLP1-RA intensive treatment regimen, and about 45% of patients need to use long-acting and rapid-acting insulin at the same time to balance the basal blood glucose and postprandial blood glucose. However, the fixed ratio mixed injection liquid on the current market, such as insulin aspart (fixed ratio of 70:30) insulin degludec and liraglutide (ratio of 20:1), although it can simplify the injection process, but due to the difference in individual metabolic rate of patients, it leads to 15%-20% of patients with excessive blood glucose fluctuations or drug waste. In addition, the existing injection equipment lacks the function of independent dose adjustment, which makes doctors need to frequently change different types of injection pens when adjusting the treatment plan, not only increasing the operation burden of patients, but also may cause hypoglycemia and other serious complications due to dose error; Therefore, in the actual treatment process of clinical, medical staff realizes independent and accurate adjustment and dynamic mixing of drug dose through innovative mechanical-electronic linkage system. The core structure includes double-cavity injection system, intelligent driving module and fluid mixing assembly: the double-cavity injection system is composed of two independently sealed injection cavities 2, which can load different types of drugs respectively; the intelligent driving module controls the rotating speed of the speed regulating motor 4 through the microprocessor, and converts the rotary motion of the motor into the linear motion of the piston 201 through the screw rod 5 transmission mechanism, realizing the dose adjustment of 0.1 μl level; the fluid mixing assembly adopts Y-shaped mixing tee 3 combined with propeller type micro paddle 301 design, which drives the paddle to rotate by using the kinetic energy generated by the flow of drug solution, and completes the uniform mixing of two kinds of drug solution within 3-5 seconds, effectively avoiding the problem of decreased absorption efficiency caused by drug stratification. In addition, the equipment integrates touch operation interface, supports functions such as preset dose, injection record query, etc., which significantly improves the convenience and treatment compliance of patients.

[0013] Specifically: An adjustable double-cavity insulin injection pen, comprising: an L-shaped plate; The L-shaped plate 1 is symmetrically provided with an injection cavity 2 at the front, and a limiting groove 101 is symmetrically formed in the middle of the L-shaped plate 1; The L-shaped plate 1 is integrally provided with a mounting box 102 at the lower part of the rear end, and a battery 1031 box 103 is integrally provided at the upper part of the rear end of the L-shaped plate 1, and a control panel 104 is integrally provided at the upper end of the front of the L-shaped plate 1; The injection cavity 2 is movably mounted with a piston 201 inside, and the injection cavity 2 is sealingly connected with a mixing tee 3 at the front end; The installation box 102 is internally symmetrical to the speed regulating motor 4; the output shaft of the motor is rotationally connected with the L-shaped plate 1; the front end of the output shaft of the motor is keyed to the gear disc 401; The screw rod 5 is rotationally installed inside the limiting groove 101; the rear end of the screw rod 5 is integrally provided with a gear disc 5011 which is meshingly connected with the gear disc 401; In the embodiment, the mixing tee 3 is Y-shaped, and the two liquid inlets of the mixing tee 3 are inserted into the symmetrical injection cavities 2; the liquid outlet of the mixing tee 3 is movably connected with the disposable sterile injection needle; the mixing tee 3 receives two kinds of drugs and inputs the two kinds of drugs into the disposable sterile injection needle through the liquid outlet of the mixing tee 3; The micro paddle 301 is rotationally installed inside the intersection of the mixing tee 3; In the embodiment, the diameter of the micro paddle 301 is matched with the inner diameter of the intersection of the mixing tee 3, and the blades of the micro paddle 301 are spirally distributed; the micro paddle 301 is rotationally connected with the inner wall of the mixing tee 3 through the symmetrical micro bearings at both ends, and the micro bearings reduce the friction of the micro paddle 301; under the normal liquid driving, the rotating speed of the micro paddle 301 is between 150-200 rpm; In the embodiment, the control panel 104 includes a display screen, control buttons and a microprocessor, and the microprocessor is electrically connected with the display screen, the control buttons and the speed regulating motor 4; the rotating speed of the speed regulating motor 4 is input through the control panel 104 to realize the rotating speed control of the speed regulating motor 4; In the embodiment, the battery 1031 is installed in the battery box 103 through the clamping slot buckle, and the battery 1031 provides power supply for the control panel 104 and the speed regulating motor 4; the battery 1031 is a common prior art, including but not limited to: dry batteries 1031, lithium batteries 1031, secondary batteries 1031 (nickel-hydrogen batteries 1031, nickel-cadmium batteries 1031, etc.); specifically, if a rechargeable battery 1031 such as a secondary battery 1031 is used, a corresponding charging port can be arranged on the battery box 103 according to the actual situation; however, experience in clinical use shows that the dry battery 1031 has the highest practicability, can maintain long-time power supply and quick battery replacement to ensure the endurance; In the embodiment, the straight rod 211 is integrally arranged on the rear end of the rod body of the piston 201, the lower end of the straight rod 211 is slidingly installed inside the limiting groove 101, and a screw hole is arranged to be threadedly connected with the screw rod 5 in the limiting groove 101; the screw rod 5 is driven to rotate by the speed regulating motor 4, the straight rod 211 is controlled to slide in the limiting groove 101, and the injection of insulin in the injection cavity 2 is realized.

[0014] Specific use method: Drug loading and parameter setting: Load the drug solution into the symmetrically arranged injection cavity 2, such as injecting insulin and GLP1-RA into the corresponding cavity through the liquid injection port at the top of the injection cavity 2, and ensure that the piston 201 is completely reset to exclude air. Set the drug dose of each cavity through the control panel 104, such as 12U of long-acting insulin and 0.6mg of GLP1-RA, input the injection ratio of the two drug solutions through the controller, and the control panel 104 automatically calculates the required injection speed according to the injection ratio and displays it in real time on the display screen. Injection execution process: Start the speed regulation motor 4 through the control panel 104, and the microprocessor sends control signals to the two sides of the speed regulation motor 4 according to the preset parameters. For example, at an injection speed of 1U / 10s, the left motor is driven to rotate at a speed of 20rpm to drive the screw rod 5 to rotate and push the piston 201 forward; the right motor is synchronized to work at a speed of 15rpm to ensure that the two drugs are injected synchronously according to the set ratio into the mixing tee 3. The micro paddle 301 automatically stirs at a speed of 150-200rpm under the impact of the drug solution, realizes the full mixing of the drugs, and then injects through the needle. Personalized adjustment: For patients with large postprandial blood glucose fluctuations, the ratio of rapid-acting insulin to GLP1-RA can be temporarily adjusted, such as increasing the dose of rapid-acting insulin from 8U to 10U, and the system automatically optimizes the speed of the two motors to ensure the accuracy of the mixing ratio. After the injection is completed, the device automatically records the medication data, which is convenient for doctors to remotely monitor the treatment effect.

[0015] Through clinical application, the corresponding product of the application has a more significant effect, as follows: Dose accuracy is improved: Through clinical testing and comparison, the dose error rate of the application is ≤±2% in the dose range of 1-30U, which is significantly better than the traditional fixed ratio injection pen (error rate is about ±8%), which can effectively reduce the risk of hypoglycemia. Mixing efficiency is optimized: During the clinical treatment process, in order to ensure the fullness of drug mixing, high-speed photography technology is used to observe that the micro paddle 301 can make the two drug solutions reach a mixing uniformity of more than 98% within 5 seconds, which is 60% higher than the mixing efficiency without stirring design, and accelerates the drug onset time by about 15-20 minutes. Patient compliance is improved: After 200 patients used the device for 3 months, 92% of the patients thought that the device simplified the injection process, and 87% of the patients expressed that the dose adjustment function made it easier for them to control blood glucose levels, significantly improving treatment confidence and quality of life.

[0016] In summary, the present application sets up the deficiency of the prior art adjustable double-cavity insulin injection pen, discloses an adjustable double-cavity insulin injection pen, which comprises an L-shaped plate 1, injection cavities 2, a piston 201, a speed regulating motor 4, a control panel 104, a battery 1031 and a screw rod 5; the injection cavities 2 symmetrically arranged on the L-shaped plate 1 are respectively loaded with different drugs, such as insulin and GLP1-RA, and the rotational speed of the speed regulating motor 4 on the two sides can be independently adjusted through the control panel 104, the screw rod 5 is driven to control the injection speed of the piston 201, the dose of different drug components can be accurately adjusted, the individual difference requirements of patients are met, and the problem that the dose of the fixed proportion mixed injection liquid cannot be flexibly adjusted is solved. And a mixing tee 3 is arranged, the liquid inlet of the Y-shaped mixing tee 3 is correspondingly connected with the liquid outlets of the two injection cavities 2, and a micro paddle 301 is arranged at the intersection of the mixing tee 3, the rotational resistance is reduced through a micro bearing, when the two injection cavities 2 inject the drugs into the mixing tee 3, the micro paddle 301 is rotated by the liquid to stir the two kinds of liquid in the mixing tee, so that the mixing is uniform, and the drug absorption efficiency is improved.

[0017] The preferred embodiments of the present application disclosed above are only used to help illustrate the present application, the preferred embodiments do not describe all the details, and the present application is not limited to the specific embodiments described.

Claims

1. An adjustable dual-chamber insulin injection pen, characterized in that: include: L-shaped plate; The injection cavity is symmetrically arranged at the front of the L-shaped plate, and the limiting groove is symmetrically arranged in the middle of the L-shaped plate; The lower portion of the rear end of the L-shaped plate is integrally provided with an installation box, the upper portion of the rear end of the L-shaped plate is integrally provided with a battery box, and the upper portion of the front end of the L-shaped plate is integrally provided with a control panel; A piston is movably installed inside the injection chamber, and the front end of the injection chamber is sealed and connected to a mixing tee; The speed regulating motor is symmetrically arranged inside the installation box; the output shaft of the motor is rotatably connected to the L-shaped plate; the front end of the output shaft of the motor is keyed to the gear disk; A screw is rotatably installed inside the limiting groove; a gear disc is integrally provided at the rear end of the screw to engage with the gear disc.

2. The adjustable dual-chamber insulin injection pen according to claim 1, characterized in that: The mixing tee is Y-shaped, and the two liquid inlets of the mixing tee are plugged into the liquid outlets of the injection cavity symmetrically arranged; the liquid outlet of the mixing tee is movably connected to a disposable sterile injection needle; A micro-paddle disc is rotatably installed inside the cross position of the mixing tee.

3. The adjustable dual-chamber insulin injection pen according to claim 1, characterized in that: The diameter of the micro-paddle disc is adapted to the inner diameter of the intersection of the mixing tee, and the blades of the micro-paddle disc are distributed in a spiral shape; micro-bearings are symmetrically arranged at both ends of the micro-paddle disc to rotatably connect to the inner wall of the mixing tee, and the friction force of the rotation of the micro-paddle disc is reduced by the micro-bearings.

4. The adjustable dual-chamber insulin injection pen according to claim 1, characterized in that: The control panel includes a display screen, control buttons and a microprocessor, and the microprocessor is electrically connected to the display screen, control buttons and speed regulating motor respectively; the rotation rate of the speed regulating motor is input through the control panel to realize the speed control of the speed regulating motor.

5. The adjustable dual-chamber insulin injection pen according to claim 1, characterized in that: The battery is installed in a snap-on manner in the internal slot of the battery box, and the battery provides power supply for the control panel and the speed regulating motor.

6. The adjustable dual-chamber insulin injection pen according to claim 1, characterized in that: A straight rod is integrally provided on the rear end rod body of the piston, and the lower end of the straight rod is slidably installed inside the limiting groove, and a screw hole is provided to be threadedly connected to the screw in the limiting groove. The screw is driven to rotate by the speed regulating motor to control the straight rod to slide in the limiting groove, thereby realizing the push injection of insulin inside the injection cavity.

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