Incubator calibration method and system
Flexible calibration of temperature chamber calibration software configuration parameters solves temperature deviation problems caused by temperature chamber sensor aging and environmental fluctuations, achieving experimental consistency and effective equipment maintenance.
Patent Information
- Application Number
- CN202510982013.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-16
- Publication Date
- 2025-10-17
AI Technical Summary
Temperature chamber sensors and control components may deviate from set values due to aging or environmental fluctuations, affecting experimental consistency and equipment life.
The temperature chamber is calibrated using calibration software with flexible configuration parameters, supporting different temperature points and types, identifying and correcting deviations, and generating calibration reports that can be sent to the LIMS system.
Ensure the consistency of the experimental environment, extend the life of the equipment, reduce production accidents, detect potential problems in time, and maintain the equipment in the best condition.
Smart Images
Figure CN120800591A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of temperature chamber equipment, and in particular to a temperature chamber calibration method and system thereof. Background Art
[0002] The sensors and control components of temperature chambers (such as constant temperature chambers and high-low temperature chambers) can age, drift, or lose accuracy over time, causing actual temperatures to deviate from setpoints. For example, reduced cooling system efficiency or heating element wear can cause systemic deviations. External environmental fluctuations (such as voltage instability, sudden changes in temperature and humidity), as well as frequent equipment startups and shutdowns, can accelerate the degradation of internal components and increase the risk of temperature control errors, necessitating regular calibration. Summary of the Invention
[0003] The purpose of the present invention is to solve the above-mentioned technical problems and provide a new type of temperature chamber calibration method and system. By sending the calibration report to the LIMIS system through the calibration software, it is convenient to query the calibration report and trace back the problem later; the calibration configuration parameters are flexible and support different calibration temperature points and different types of temperature chamber calibration; the calibration can identify and correct the temperature chamber deviation, and can detect potential problems such as sensor failure and refrigerant leakage at an early stage, and carry out timely repair and maintenance, thereby extending the service life of the equipment and maintaining the best working condition; the calibration software can ensure the environmental consistency of different batches of experiments; it guarantees the quality stability between product batches and reduces production accidents caused by environmental fluctuations.
[0004] The present invention is achieved through the following technical solutions: A temperature chamber calibration method comprises the following steps: S1: First install the calibration software on the computer, then open the calibration software and edit the calibration configuration parameters. The calibration configuration parameters include the temperature chamber configuration parameters, the thermometer configuration parameters and the upper limit of the calibration temperature difference. The temperature chamber configuration parameters include IP, port number, temperature value ratio, temperature deviation value, temperature control timeout time, temperature chamber register address configuration and A calibration temperature value; Thermometer configuration parameters include IP and port number; S2: After the calibration configuration parameters are edited in step S1, click Start again. The calibration software connects to the incubator according to the incubator configuration parameters, and the calibration software connects to the thermometer according to the thermometer configuration parameters. Calibration temperature value Indicate, use Indicates the index of the calibration temperature value. The initial value of is 1; S3: Judgment Is it greater than If yes, generate a calibration report and execute step S9, if no, execute step S4; S4: use Represents an index The calibration temperature value is Indicates the temperature value ratio. The calibration software sends a command to the temperature chamber. The value is written into the set temperature register; the calibration software sends a command to the temperature box to set the status of the start-stop register to start, and records the start time of temperature control; S5: The calibration software reads the value of the display temperature register from the temperature chamber and divides it by Get the sample value, use Indicates the sample value, using Indicates temperature deviation value; S6: Judgment Whether to satisfy both and If yes, execute step S7; if no, execute temperature control timeout judgment to determine whether the difference between the current time and the temperature control start time is less than the temperature control timeout time. If yes, execute step S5; if no, generate a calibration report and execute step S9; S7: The calibration software reads the temperature value from the thermometer as the standard value and uses express, judge Is it less than the upper limit of the calibration temperature difference? If so, execute step S8; if not, generate a calibration report and execute step S9; S8: The calibration software reads the value of the temperature sensor register from the temperature chamber. Indicates that the calibration software sends instructions to the temperature chamber. Write the setting value register and The value of the reference value register is written into the reference value register; Add 1 and execute step S3; S9: After the calibration is completed, the human-computer interaction interface of the calibration software displays the calibration report information in real time and sends the calibration report to the LIMS system.
[0005] Furthermore, the calibration report includes calibration start time, calibration end time, calibration temperature value, sampling value, standard value, equipment information, calibration result and calibration failure reason, wherein the calibration result includes success and failure.
[0006] As a further feature, the device information includes the model of the thermometer, the asset number of the thermometer, the type of the incubator, and the unique code of the incubator.
[0007] As a further feature, the thermostat register address configuration includes a start / stop register address, a set temperature register address, a display temperature register address, a set value register address, a reference value register address and a temperature sensor register address.
[0008] The application discloses a temperature box calibration system, which comprises a temperature box, a temperature detector, calibration software and a LIMS system, wherein the temperature box comprises a start-stop register, a set temperature register, a display temperature register, a set value register, a reference value register and a temperature sensor register; the calibration software is installed on a computer, the LIMS system is installed on a cloud server, the calibration software installed on the computer is connected with the cloud server through the Internet, and the calibration software installed on the computer and the temperature box and the temperature detector are located in a communicable local area network.
[0009] Further, the start-stop register comprises two states of starting and stopping.
[0010] Further, the calibration software communicates with the temperature box through a Modbus TCP protocol, communicates with the temperature detector through an XCP or FTP protocol, and communicates with the LIMS system through a WebService or WebApi interface.
[0011] Further, the temperature box is a constant-temperature temperature box or a high-low temperature box.
[0012] The application has the following beneficial effects: (1) The calibration software can send a calibration report to the LIMIS system, so that the calibration report and problem backtracking can be conveniently inquired in the later period; (2) The calibration software has flexible configuration parameters and supports calibration of different calibration temperature points and different types of temperature boxes; (3) The calibration software can identify and correct the deviation of the temperature box, can early discover potential problems such as sensor failure and refrigerant leakage, can be timely maintained, can prolong the service life of the equipment and can maintain the best working state; (4) The calibration software can ensure the environmental consistency of different batches of experiments, can guarantee the quality stability between product batches and can reduce production accidents caused by environmental fluctuations. DETAILED DESCRIPTION
[0013] Figure 1 It is a temperature box calibration method flowchart of the application; Figure 2 It is a temperature box calibration system schematic diagram of the application; Figure 3 It is a temperature box calibration system internal schematic diagram of the application. DETAILED DESCRIPTION
[0014] The application will be further described below in combination with the drawings and specific embodiments: Unless otherwise defined, all technical and scientific terms used herein have the same meanings as commonly understood by those skilled in the art to which this application belongs. The terms used in the specification of the application are only for the purpose of describing specific embodiments and are not intended to limit this application. The terms "including" and "having" and any variations thereof in the specification and claims of this application and the above-mentioned drawings are intended to cover non-exclusive inclusions. The terms "first", "second", etc. in the specification and claims of this application or the above-mentioned drawings are used to distinguish different objects, not to describe a specific order.
[0015] References herein to "embodiments" mean that a particular feature, structure, or characteristic described in connection with the embodiments may be included in at least one embodiment of the present application. The appearance of this phrase in various places in the specification does not necessarily refer to the same embodiment, nor does it constitute an independent or alternative embodiment that is mutually exclusive of other embodiments. It is understood, both explicitly and implicitly, by those skilled in the art that the embodiments described herein may be combined with other embodiments.
[0016] Refer to Figure 1 As shown, a temperature chamber calibration method includes the following steps: S1: First install the calibration software on the computer, then open the calibration software and edit the calibration configuration parameters. The calibration configuration parameters include the temperature chamber configuration parameters, the thermometer configuration parameters and the upper limit of the calibration temperature difference. The temperature chamber configuration parameters include IP, port number, temperature value ratio, temperature deviation value, temperature control timeout time, temperature chamber register address configuration and A calibration temperature value; Thermometer configuration parameters include IP and port number; S2: After the calibration configuration parameters are edited in step S1, click Start again. The calibration software connects to the incubator according to the incubator configuration parameters, and the calibration software connects to the thermometer according to the thermometer configuration parameters. Calibration temperature value Indicate, use Indicates the index of the calibration temperature value. The initial value of is 1; S3: Judgment Is it greater than If yes, generate a calibration report and execute step S9, if no, execute step S4; S4: use Represents an index The calibration temperature value is Indicates the temperature value ratio. The calibration software sends a command to the temperature chamber to The value is written into the set temperature register; the calibration software sends a command to the temperature box to set the status of the start-stop register to start, and records the start time of temperature control; S5: The calibration software reads the value of the display temperature register from the temperature chamber and divides it by Get the sample value, use Indicates the sample value, using Indicates temperature deviation value; S6: Judgment Whether to satisfy both and If yes, execute step S7; if no, execute temperature control timeout judgment to determine whether the difference between the current time and the temperature control start time is less than the temperature control timeout time. If yes, execute step S5; if no, generate a calibration report and execute step S9; S7: The calibration software reads the temperature value from the thermometer as the standard value and uses express, judge Is it less than the upper limit of the calibration temperature difference? If so, execute step S8; if not, generate a calibration report and execute step S9; S8: The calibration software reads the value of the temperature sensor register from the temperature chamber. Indicates that the calibration software sends instructions to the temperature chamber. Write the setting value register and The value of the reference value register is written into the reference value register; Add 1 and execute step S3; S9: After the calibration is completed, the human-computer interaction interface of the calibration software displays the calibration report information in real time and sends the calibration report to the LIMS system.
[0017] Preferably, the calibration report includes calibration start time, calibration end time, calibration temperature value, sampling value, standard value, equipment information, calibration result and calibration failure reason, wherein the calibration result includes success and failure.
[0018] Preferably, the device information includes the model of the thermometer, the asset number of the thermometer, the type of the thermostat and the unique code of the thermostat.
[0019] Preferably, the oven register address configuration includes a start / stop register address, a set temperature register address, a display temperature register address, a set value register address, a reference value register address and a temperature sensor register address.
[0020] Refer to Figure 2As shown in the description, a temperature box calibration system comprises a temperature box, a temperature detector, calibration software and a LIMS system, the temperature box comprises a start-stop register, a set temperature register, a display temperature register, a set value register, a reference value register and a temperature sensor register; the calibration software is installed on a computer, the LIMS system is installed on a cloud server, the calibration software installed on the computer is connected with the cloud server through the Internet, and the calibration software installed on the computer and the temperature box and the temperature detector are in the same local area network which can communicate.
[0021] As preferably, the start-stop register comprises two states of starting and stopping.
[0022] Referring to the description as Figure 3 As shown in the description, the calibration software communicates with the temperature box through the Modbus TCP protocol, communicates with the temperature detector through the XCP or FTP protocol, and communicates with the LIMS system through the WebService or WebApi interface.
[0023] As preferably, the temperature box is a constant temperature oven or a high-low temperature oven.
[0024] According to the disclosure and teaching of the above description, those skilled in the art of the present application can also make appropriate changes and modifications to the above embodiments. Therefore, the present application is not limited to the specific embodiments disclosed and described above, and some modifications and changes of the present application should fall within the protection scope of the claims of the present application. In addition, although some specific terms are used in the description, these terms are only for convenience of description and do not constitute any limitation on the present application.
Claims
1. A temperature chamber calibration method, characterized in that: The steps include: S1: First install the calibration software on the computer, then open the calibration software and edit the calibration configuration parameters. The calibration configuration parameters include the temperature chamber configuration parameters, the thermometer configuration parameters and the upper limit of the calibration temperature difference. The temperature chamber configuration parameters include IP, port number, temperature value ratio, temperature deviation value, temperature control timeout time, temperature chamber register address configuration and A calibration temperature value; Thermometer configuration parameters include IP and port number; S2: After the calibration configuration parameters are edited in step S1, click Start again. The calibration software connects to the incubator according to the incubator configuration parameters, and the calibration software connects to the thermometer according to the thermometer configuration parameters. Calibration temperature value Indicate, use Indicates the index of the calibration temperature value. The initial value of is 1; S3: Judgment Is it greater than If yes, generate a calibration report and execute step S9, if no, execute step S4; S4: use Represents an index The calibration temperature value is Indicates the temperature value ratio. The calibration software sends a command to the temperature chamber. The value is written into the set temperature register; the calibration software sends a command to the temperature box to set the status of the start-stop register to start, and records the start time of temperature control; S5: The calibration software reads the value of the display temperature register from the temperature chamber and divides it by Get the sample value, use Indicates the sample value, using Indicates temperature deviation value; S6: Judgment Whether to satisfy both and If yes, execute step S7; if no, execute temperature control timeout judgment to determine whether the difference between the current time and the temperature control start time is less than the temperature control timeout time. If yes, execute step S5; if no, generate a calibration report and execute step S9; S7: The calibration software reads the temperature value from the thermometer as the standard value and uses express, judge Is it less than the upper limit of the calibration temperature difference? If so, execute step S8; if not, generate a calibration report and execute step S9; S8: The calibration software reads the value of the temperature sensor register from the temperature chamber. Indicates that the calibration software sends instructions to the temperature chamber. Write the setting value register and The value of the reference value register is written into the reference value register; Add 1 and execute step S3; S9: After the calibration is completed, the human-computer interaction interface of the calibration software displays the calibration report information in real time and sends the calibration report to the LIMS system.
2. The temperature chamber calibration method according to claim 1, characterized in that: The calibration report includes calibration start time, calibration end time, calibration temperature value, sampling value, standard value, equipment information, calibration result and calibration failure reason, wherein the calibration result includes success and failure.
3. The temperature chamber calibration method according to claim 2, characterized in that: The device information includes the model of the thermometer, the asset number of the thermometer, the type of the incubator, and the unique code of the incubator.
4. The temperature chamber calibration system according to claim 1, wherein: The thermostat register address configuration includes a start / stop register address, a set temperature register address, a display temperature register address, a set value register address, a reference value register address and a temperature sensor register address.
5. A temperature chamber calibration system, characterized in that: The invention comprises a thermostat, a thermometer, calibration software and a LIMS system. The thermostat comprises a start / stop register, a set temperature register, a display temperature register, a set value register, a reference value register and a temperature sensor register. The calibration software is installed on a computer, and the LIMS system is installed on a cloud server. The calibration software installed on the computer is connected to the cloud server via the Internet, and the calibration software installed on the computer is in the same local area network as the thermostat and the thermometer.
6. The temperature chamber calibration system according to claim 5, characterized in that: The start-stop register includes two states: start and stop.
7. The temperature chamber calibration system according to claim 5, characterized in that: The calibration software communicates with the temperature box via the Modbus TCP protocol, the calibration software communicates with the thermometer via the XCP or FTP protocol, and the calibration software communicates with the LIMS system via the WebService or WebApi interface.
8. The temperature chamber calibration system according to claim 5, wherein: The temperature box is a constant temperature box or a high and low temperature box.